Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Charlotte Komuhangi
ID: UNCST-2025-R018038
A Phenomenological Study of Premarital Counselling Experiences and Challenges among Married Christians in Rubaga Division, Kampala, Uganda.
REFNo: SS4390ES

i. To explore the perceptions about premarital counseling among married Christians in Rubaga division.
ii. To examine the marital experiences of married Christians in Rubaga Division who have gone through premarital counseling.
iii. To analyse the opinion of married Christians in Rubaga Division on what can be done to improve premarital counseling

Uganda 2025-10-16 9:10:29 2028-10-16 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Kambugu
ID: UNCST-2019-R000823
Evaluation of the Impact of the Epidemic Ready Primary Health Care Project on Outbreak Preparedness and Response in Primary Healthcare Facilities in Uganda.
REFNo: HS6147ES

To document challenges, best practices, and lessons learned during project implementation,To assess the rollout and the associated change in knowledge of healthcare workers trained using the clinical IDSR (cIDSR)digital training platform. ,To assess health facilities’ epidemic readiness using simulated patient exercises.,To assess the impact of the ERPHC longitudinal health worker capacity building mentorship on epidemic readiness: Surveillance, Infection Prevention and Control, and Case Management.,To evaluate the impact of the Epidemic Ready Primary Health Care project on outbreak preparedness and response in primary healthcare facilities in Uganda. ,
Uganda 2025-10-16 9:09:31 2028-10-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Erasmus Oreret Tukei
ID: UNCST-2024-R002444
PREVENTING ZOONOTIC DISEASE IN UGANDA’S GREAT APES (GORILLAS AND CHIMPANZEES): EVALUATING THE EFFICACY OF DISEASE PREVENTION TRAINING AND RESPONSIBLE TOURISM BEST PRACTICES
REFNo: NS1000ES

The overall objective is to evaluate the effectiveness of ranger trainings, informational tourist videos, and best practices in promoting responsible tourism and disease prevention at Kibale National Park (KNP; chimpanzees) and Bwindi Impenetrable National Park (BINP; gorillas). The research aims to assess changes in knowledge and behavior among rangers, tourists, and tour operators through surveys and behavioral assessments.,To assess the level of satisfaction among the tourist involved in Gorillas and Chimpanzee trekking in Bwindi Impenetrable National Park and Kibale National Park.,To assess knowledge and attitudes related to zoonotic disease risks and prevention best practices among tourists and rangers before and after the training sessions. ,
Uganda 2025-10-16 9:07:32 2028-10-16 Natural Sciences Non-Clinical Trial Degree Award
Justine Okello
ID: UNCST-2024-R005435
Determinants of Rift Valley Fever (RVF) Disease at The Human-Animal-Environment Interface in Lira and Apac Districts of Northern Uganda
REFNo: HS6654ES

To assess the capacity of the study districts to handle any outbreaks of Viral Heamorragic fevers including Rift Valley fever diseaseTo explore the Rift valley disease management in Lira and Apac Districts of Northern UgandaTo determine the sero-prevalence and associated risk factors of RVF disease among humans and domestic livestock at the human-animal and environment interface in Apac and Lira Districts of Northern Uganda
Uganda 2025-10-16 9:05:52 2028-10-16 Medical and Health Sciences Degree Award
KALINDA  PETER
ID: UNCST-2023-R007263
TIER FOUR MICROFINANCE SERVICES AND HOUSEHOLDS’ SOCIAL-ECONOMIC WELL-BEING OF SMALLHOLDER FARMERS IN SOUTHWESTERN UGANDA
REFNo: SS2332ES

4) To examine the mediating effect of financial literacy in the relationship between microfinance services and social-economic wellbeing of smallholder farmers in South Western Uganda.,3) To establish the relationship between financial literacy and social economic wellbeing of smallholder farmers in South Western Uganda.,2) To examine the relationship between microfinance services and financial literacy among smallholder farmers in South Western Uganda.,1) To examine the relationship between microfinance services and social-economic wellbeing of smallholder farmers in South Western Uganda.,The study is set out to examine the mechanism by which microfinance services are related to social-economic wellbeing among smallholder farmers in South Western Uganda. ,
Uganda 2025-10-16 9:02:54 2028-10-16 Social Science and Humanities Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women
REFNo: HS6666ES

To evaluate the efficacy of MK-8527 qm
compared to FTC/TDF qd for the
prevention of HIV-1 infection as assessed
by the incidence rate per year of adjudicated
HIV-1 infections.
Hypothesis: MK-8527 qm is superior to
FTC/TDF qd with respect to the hazard
ratio for HIV-1 infecti
Uganda 2025-10-16 17:51:09 2028-10-16 Medical and Health Sciences Clinical Trial Non-degree Award
Samuel Maling
ID: UNCST-2023-R008367
Oral Health Services’ Integration into Routine HIV Care among older adults in Uganda
REFNo: HS5802ES

1. To identify barriers to and facilitators of integrating oral health services into routine HIV care. 2. To determine oral health disparities and needs affecting oral health care among older adults in southwestern Uganda
Uganda 2025-10-15 17:25:23 2028-10-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SARAH NAKIYINGI
ID: UNCST-2024-R002026
DETERMINANTS OF STUDENTS TRANSFER IN PRIVATE UNIVERSITIES IN KAMPALA - UGANDA
REFNo: SS4111ES

1. To find the relationship between Personal factors and students transfers in private universities in Kampala –Uganda. 2. To examine the relationship between institutional factors and student transfer in private universities in Kampala –Uganda. 3. To assess the relationship of financial and non-financial factors on student transfer 4. To examine the combined effect of personal and institutional factors on student transfer in Kampala – Uganda. 5. To assess the experiences of student transfer in their new academic institutions 6. To find out the strategies of student retention in private universities in Kampala –Uganda.
Uganda 2025-10-15 17:22:54 2028-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Daisy Aliwaru
ID: UNCST-2025-R018043
University Management and Pedagogical Innovations in Education: A Comparative Study of Public and Private Universities in Uganda.
REFNo: SS3974ES

1. To analyze the university management structures and practices that support pedagogical innovations in education at Muni University and Uganda Christian University.
2. To examine the effect of resource allocation for pedagogical innovations in education at Muni University and Uganda Christian University.
3. To determine the effect of incentives on pedagogical innovations in education at Muni University and Uganda Christian University.
4. To examine the effect of academic freedom for pedagogical
innovations in education at Muni University and Uganda Christian University.

Uganda 2025-10-15 16:44:31 2028-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Naomi Matthews Eleanor
ID: UNCST-2019-R000918
Pilot Investigations into giant pangolin, Smutsia gigantic, in the Kibale Conservation Area, Uganda
REFNo: NS50ES

• Learn to recognise indirect signs of giant pangolin and develop survey/monitoring techniques • Identify habitat preferences of giant pangolin • Determine presence/absence throughout the park through reconnaissance surveys and camera trapping methods • Develop preliminary estimates of occupancy, relative abundance and home range size • Gather biometric and behavioural information to guide best practice for future radio/GPS tagging study
UK 2025-10-15 10:31:44 2028-10-15 Natural Sciences Non-degree Award
Kellen Tumutegyereize Busingye
ID: UNCST-2025-R017809
Faculty Pedagogical Practices in Leveraging Digital Technologies to Enhance Inclusive Learning in Public Universities; Uganda.
REFNo: SS4455ES

1.To explore faculty perceptions towards leveraging digital technologies in fostering inclusive learning environments. 2.To analyse how faculty use digital technologies to prepare for delivery of instruction that presents content in multiple formats. 3.To examine how faculty utilize digital technologies to facilitate multiple means of student engagement during the teaching-learning process. 4.To assess how faculty use digital technologies to provide students with multiple options for demonstrating their learning progress.
Uganda 2025-10-14 10:20:25 2028-10-14 Social Science and Humanities Non-Clinical Trial Degree Award
Grace Ndeezi
ID: UNCST-2019-R001802
Understanding and managing fevers from infections spread by animals Multi-centre study Protocol version 2.0, 17 July 2025
REFNo: HS6492ES

Our overarching goal is to improve the diagnosis and management of zoonotic causes of acute febrile illness (ZAFI) in paediatric populations in sub-Saharan Africa.
The specific aims and objectives are to:
1. Determine the common causes of ZAFI and associated factors in paediatric patients living in urban and rural areas of Uganda, Kenya and Ethiopia
1.1. Quantify the burden of non-malarial fever and identify the major zoonotic aetiologies
1.2. Identify risk factors for and clinical indicators of infection with specific zoonotic pathogens
2. Develop and test novel technologies and approaches for diagnosing ZAFI that are suitable for use in LMIC and field settings
2.1. Evaluate point-of-care (PoC) tests and pilot prototype molecular diagnostic platforms for key zoonotic pathogens
2.2. Determine the best sequence of tests to optimise diagnosis of fever
3. Involve communities and the health sector in Uganda, Kenya and Ethiopia in defining improved approaches to diagnosis and management of ZAFI
3.1. Identify community perceptions on the causes of AFI and care seeking behaviours for fever
3.2. Develop and validate a decision support tool for diagnosis and management of ZAFI in clinical settings
4. Strengthen capacity and capability for research on diagnosis and management of zoonotic diseases in Uganda, Kenya and Ethiopia
4.1. Develop and implement evidence-based capacity strengthening plans to ensure that all partner affiliated laboratories have the capability to perform quality-assured molecular diagnostics research for zoonotic infections
4.2. Develop a cohort of clinical and laboratory scientists with expertise in ZAFI

Uganda 2025-10-10 13:30:11 2028-10-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DORCAS LAMUNUOWOT
ID: UNCST-2025-R018451
Effectiveness of health education intervention on malaria control during pregnancy in rural communities: A case of Lamwo district in Northern Uganda.
REFNo: HS6569ES

1. Assess the current knowledge and awareness, attitude, and practices regarding malaria control among pregnant women in Lamwo District, Northern Uganda.
2. To adapt and implement the culturally tailored health education intervention targeting malaria control and prevention among pregnant women in Lamwo district, Northern Uganda
3. Assess the effectiveness of health education intervention on improving knowledge, attitudes, and practices regarding malaria control among pregnant women in Lamwo district, Uganda.
4. To explore the perceptions and experiences of midwives and pregnant women regarding the implementation and impact of the health education intervention for malaria control and prevention in pregnancy in Lamwo district, Northern Uganda.

Uganda 2025-10-08 9:57:08 2028-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Sarah Kristiansen
ID: UNCST-2023-R007322
Supporting Ugandan Caregivers in Teaching Menstrual Care Skills to Individuals with Developmental Disabilities
REFNo: SS4157ES

To understand the effects of a program designed to teach parents and educators of individuals with developmental disabilities instructional procedures for teaching menstrual care skills to the young women they care for. Additionally, to understand the effects of a training program to teach an educator from the sponsor organization, Home of Hope, to continue with training procedures to promote sustainability.
USA 2025-10-08 8:29:05 2028-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
Ahna Ballonoff Suleiman
ID: UNCST-2025-R019613
Thrive Together: Strengthening Contraception through Lived Experience of Flourishing
REFNo: SS4403ES

1. Bring existing, validated VFP and human flourishing frameworks and evidence into rigorous dialogue; 2. ground understanding of common VFP and human flourishing domains in lived experience expertise of culturally diverse young people, women and couples; 3. Engender first-ever expert consensus on the common domains of human flourishing and VFP; 4. Deliver evidence-based, consolidated guidance to programmers and decision-makers to advance VFP as part of human flourishing, and human flourishing as part of VFP.
USA 2025-10-08 19:23:37 2028-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
Understanding the Effects of Behavioural Risk Factors and Lifestyle Changes Among Non-overweight and Obese Type 2 Diabetes Mellitus Patients in Malawi and Uganda.
REFNo: HS6497ES

Main Objective:
• To determine whether behavioural risk factors (diet and physical activity) contribute to NOW T2DM and to assess whether current national lifestyle change guidelines have similar effects on glucose control and other outcomes among NOW and obese T2DM patients in Malawi and Uganda.

Specific Objectives:

i. To establish a cohort of newly diagnosed NOW and obese T2DM patients and matched non-diabetic controls in Malawi and Uganda.
ii. To compare baseline dietary and physical activity patterns among NOW and obese T2DM participants and their matched controls.
iii. To administer health education based on national guidelines and compare 6-month outcomes (weight loss and glucose control) in NOW versus obese participants.

Malawi 2025-10-08 19:03:35 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANN AKITENG ROSE
ID: UNCST-2025-R019916
Assessing Healthcare Barriers and Identifying Implementation Strategies to Mitigate Cardiovascular Risks Among Market Vendors in Urban Markets in Kampala and Mbarara, Uganda
REFNo: HS6472ES

The aim of this study is to generate formative quantitative data on the health status, cardiovascular disease (CVD) risk factors, daily routines, and healthcare access and barriers of market vendors in Uganda in order to identify opportunities for culturally appropriate and feasible lifestyle modification interventions and potential implementation strategies to reduce CVD risk.
Uganda 2025-10-08 18:59:30 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PATIENCE AYESIGA
ID: UNCST-2023-R003499
The implications of wetland dynamics on water qiuality for conservation of Rwizi macro catchment south western Uganda
REFNo: SS4498ES

To characterize the spatial-temporal dynamics and explore drivers of wetland degradation for middle Rwizi catchment. 2.To assess the implications of wetland degradation on sediment for middle Rwizi catchment. 3.To analyze the influence of nutrients on water quality for middle Rwizi catchment. 4.To evaluate the effectiveness of existing conservation develop suitable restoration and conservation mechanisms for improved catchment health of middle Rwizi system.
Uganda 2025-10-08 18:58:01 2028-10-08 Social Science and Humanities Degree Award
Obondo Sande James
ID: UNCST-2019-R000241
Effect of Mycobacterium tuberculosis and its cell wall glycolipids on the HIV Reservoir in CD4+ T cells
REFNo: HS5439ES

1. To determine if MTB molecules (e.g. PIM6, LAM, MTB lysate) induce HIV expression in memory CD4+ T cells from ART-suppressed HIV infected persons.

2. To determine the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB compared to HIV infected individuals with history of documented treated TB, LTBI, and no LTBI (HIV-monoinfected).

3. To assess longitudinal changes in the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB before initiation of TB treatment and at the end of treatment

Uganda 2025-10-08 18:16:22 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kansiime Cecilia
ID: UNCST-2025-R017890
OPTIMIZATION OF THE REARING SUBSTRATES FOR BLACK SOLDIER FLY LARVAE AND ITS ACCEPTABILITY AS AN ALTERNATIVE PROTEIN SOURCE AMONG POULTRY FARMERS IN THE RWENZORI REGION
REFNo: A647ES

(i) To determine the appropriate growing substrates for black soldier fly larvae as a source of protein for poultry. (ii) To assess farmers perceptions and acceptance of black soldier fly larvae as a source of protein for poultry. (iii) To determine the economic feasibility of using black soldier fly larvae as a source of protein for poultry.
Uganda 2025-10-08 13:11:23 2028-10-08 Agricultural Sciences Non-Clinical Trial Degree Award
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