Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fred  Okuku Machyo
ID:
EVALUATING THE INTEGRATION OF PEGFILGRASTIM FOR THE MANAGEMENT OF CHEMOTHERAPY-INDUCED FEBRILE NEUTROPENIA AT THE UGANDA CANCER INSTITUTE
REFNo: HS8034ES

1. To assess the feasibility and uptake of pegfilgrastim prophylaxis among eligible adult chemotherapy patients at UCI, including reach, fidelity, and vial utilization patterns.
2. To compare clinical outcomes, specifically FN incidence, infection-related hospitalizations, and chemotherapy dose delays or reductions, between pegfilgrastim recipients and historical cohorts managed without routine G-CSF prophylaxis.
3. To document baseline filgrastim prescribing patterns, dosing practices, and associated clinical outcomes prior to pegfilgrastim integration.
4. To evaluate healthcare workers’ knowledge, attitudes, and perceptions regarding FN prevention and the comparative use of pegfilgrastim versus filgrastim.
5. To identify system-level, provider-level, and process-level barriers and facilitators influencing pegfilgrastim implementation and long-term sustainability within UCI.

 Uganda 2026-07-09 19:40:59 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joan Busingye
ID: UNCST-2026-R026289
 COGNITIVE BEHAVIORAL INTERVENTIONS AND PATIENT RECOVERY AMONG INDIVIDUALS WITH MENTAL ILLNESS. A CASE OF SELECTED HOSPITALS IN CENTRAL UGANDA
REFNo: SS5507ES

1. To determine the influence of cognitive interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
2. To assess the effect of emotional interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
3. To examine the influence of behavioral interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
4. To evaluate the moderating effect of patient-related factors (age, gender, diagnosis, duration of illness, treatment adherence, and cultural beliefs) on the relationship between cognitive behavioral interventions and patient recovery in selected hospitals in Central Uganda.

 Uganda 2026-07-09 19:38:45 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Development of a Rapid Fieldable Nanopore Sequencing-based Prognostic and Diagnostic Assay to Advance Clinical Management Decision-Making
REFNo: HS7987ES

- Verify harmonized sample preparation workflow from archived biospecimens for the integrated pathogen diagnostic and host-response assay that is run on the INSPIRE device - Verify functionality of integrated software and hardware required for the INSPIRE device on archived biospecimens
Uganda 2026-07-09 19:37:11 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick ALUKU
ID: UNCST-2026-R025007
 DETERMINANTS OF MARKET ACCESS FOR SMALLHOLDER HORTICULTURE FARMERS IN MBALE DISTRICT: A CASE STUDY OF ONION AND CARROT PRODUCERS IN WANALE SUB-COUNTY...
REFNo: A803ES

This study aims to examine the determinants of market access for smallholder horticulture farmers in Mbale district: a case study of onion and carrot producers in Wanale Sub-County. Specific objectives: The study aims to achieve the following objectives: 1. To assess the effect of market infrastructure on market access for smallholder horticulture farmers in Wanale Sub-county. 2. To examine the effect of institutional support on market access for smallholder horticulture farmers in Wanale Sub-county. 3. To determine the effect of transaction costs on market access for smallholder horticulture farmers in Wanale Sub-county. 4. To find out the other factors affecting market access for smallholder horticulture farmers in Wanale Sub-county.
 Uganda 2026-07-09 19:36:00 2029-07-09 Agricultural Sciences Non-Clinical Trial Degree Award
Adalbert Aineomucunguzi
ID:
Conservation Research to Monitor Grey Crowned Cranes in Uganda through Colour Band Ringing and Aerial Surveys
REFNo: NS1291ES

1. To establish a standardized crane ringing program by fitting ELSA colour rings on 20 Grey Crowned Crane chicks annually over a five-year period.
2. To track and document movement patterns and habitat use of colour-marked cranes across breeding, foraging, and dispersal landscapes.
3. To estimate survival rates and recruitment of juvenile cranes through periodic resighting of marked individuals.
4. To generate baseline biological and ecological data (including morphometrics) to address key knowledge gaps in the species’ life cycle.
5. To strengthen evidence-based conservation planning and adaptive management for Grey Crowned Crane populations in Uganda.
6. Provide data on Grey Crowned Crane populations and their distribution in Uganda
7. Advance our understanding of landscape use (particularly agriculture) and its influence on size and distribution of crane populations
8. Identify areas where the potential exists for crane conservation interventions


Uganda 2026-07-09 19:34:31 2029-07-09 Natural Sciences Non-Clinical Trial Non-degree Award
muyunga ashiraf
ID: UNCST-2025-R021888
 CUSTOMARY LAND DISPUTES ADJUDICATION AND TENURE SECURITY IN UGANDA: A CASE STUDY OF ACHOLI SUB REGION
REFNo: SS5467ES

a)To examine the legal and institutional framework governing customary land tenure adjudication in Uganda and its applicability to the Acholi context. b) To examine the jurisprudential approaches and evidentiary standards adopted by superior courts in the adjudication of customary land disputes in the Acholi sub-region. c) To assess the impact of formal judicial outcomes on tenure security within the plural adjudicatory context of the Acholi sub-region d) To propose legal and institutional reforms for strengthening the adjudication of customary land disputes and tenure security based on findings from the Acholi subregion.
 Uganda 2026-07-09 19:33:37 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Bashemera Birungi Brenda
ID: UNCST-2025-R021775
 A Deep Learning Framework for Stroke Biomarker Detection and Prediction of Post Stroke Epilepsy in Brain CT Scans
REFNo: SIR712ES

1.Collect and curate brain CT scan image datasets. 2. Develop a deep learning segmentation model to detect stroke biomark- ers. 3. Develop a deep learning prediction model to predict the likelihood of Post Stroke Epilepsy (PSE) to a high degree of accuracy. 4. Develop Large Language Models (LLM) to provide clinical reports from the deep learning models for stroke segmentation and post-stroke epilepsy prediction.
 Uganda 2026-07-09 19:30:44 2029-07-09 Engineering and Technology Non-Clinical Trial Degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
 POPULATION-BASED EVALUATION OF THE EPIDEMIOLOGY OF NON-COMMUNICABLE DISEASES AND SOCIOCULTURAL CONTEXT AMONG ADULTS OF TWO RURAL POPULATIONS IN UGANDA.
REFNo: HS7934ES

To build a cohort platform of adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda, with linkage to routinely collected clinical and/or medico-administrative data at the health centre to answer pertinent research questions about NCDs. ,To determine the trends in prevalence and incidence of Diabetes Mellitus and Hypertension among the cohort participants in among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,To document the sociocultural determinants of health to inform the development of community-led strategies for health promotion and improved quality of life among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda. ,To determine the burden of known risk factors such as obesity, lifestyle, smoking and diet, associated with Diabetes Mellitus and Hypertension among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,.To determine the prevalence of Diabetes Mellitus and Hypertension and examine associated sociocultural factors among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,
 Uganda 2026-07-09 19:26:55 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Raymond Alinetu
ID: UNCST-2025-R022600
 PREVALENCE AND PREDICTORS OF TIME-TO-DISPOSITION AMONG ROAD TRAFFIC ACCIDENT PATIENTS AT THE EMERGENCY DEPARTMENT OF MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS7584ES

To determine the mean time-to-disposition, identify its predictors, and assess its association with early clinical outcomes among adult road traffic accident patients at the Emergency Department of Mbarara Regional Referral Hospital 1) To determine the mean time-to-disposition and the prevalence of prolonged time-to-disposition (exceeding 4 hours) among adult road traffic accident patients at the Emergency Department of Mbarara Regional Referral Hospital. 2) To identify the patient-related factors (e.g., age, injury severity, impairment), attendant-related factors (e.g., presence, relationship, decision-making capacity), and system-level factors (e.g., staffing, diagnostic service availability, time of arrival) that predict prolonged time-to-disposition among adult road traffic accident patients at the Emergency Department of Mbarara Regional Referral Hospital. 3) To determine the association between time-to-disposition and early clinical outcomes (recovery status and survival at ED disposition) among adult road traffic accident patients at Mbarara Regional Referral Hospital
Uganda 2026-07-09 19:24:38 2029-07-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
 Longitudinal Study of Oculomics in the General Population Cohort, Uganda Africa Oculomics Research Programme
REFNo: HS7940ES

Primary Objective: Our vision is to unlock the potential of Oculomics to better understand, diagnose and predict non-communicable disease (NCDs), to improve health outcomes and equity for African populations. Secondary Objectives: 1. Establish prospective ocular imaging and NCD phenotyping studies, nested within the existing General Population Cohort in Uganda. 2. Optimise artificial intelligence (AI) foundation models for ocular image analysis for this African population, and to fine-tune these models to detect several different systemic conditions. 3. Investigate cross-sectional and longitudinal associations between ocular biomarkers and major NCDs, to determine the diagnostic, prognostic and predictive potential of oculomics for these conditions. 4. Assess the prevalence, incidence, progression and risk factors for common ophthalmic conditions. 5. Report the long-term incidence, progression and risk factors for major NCDs (including CVD, Renal disease, liver disease, mental health, neurological conditions and musculoskeletal impairment).
Malawi 2026-07-09 19:22:22 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Yunia Musasizi Alele
ID: UNCST-2026-R024432
 Strategic Communication in Universities in Uganda
REFNo: SS5401ES

i. How is strategic communication practised in universities in Uganda? ii. How does stakeholder engagement shape strategic communication in universities? iii. How does an integrated communication function shape university strategic communication? iv. How does top management perception shape the strategic communication role in universities? v. How does meaning construction shape strategic communication in universities?
Uganda 2026-07-09 19:20:38 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Adalbert Aineomucunguzi
ID:
Understanding movements, behaviour, and habitat utilization of the Grey Crowned Crane in Uganda through Satellite Tracking
REFNo: NS1287ES

i. Identify core areas within the landscape utilized by cranes, determine their characteristics, explain why cranes prefer them, and assess their conservation status.
ii. Determine the timing of seasonal movements and the factors that influence them.
iii. Understand cross-border movements and their extent.
iv. Understand the home ranges of cranes during and after the breeding seasons.
v. Understand the annual survival rates of cranes and gain a better understanding of the causes of mortality.

 Uganda 2026-07-09 19:18:30 2029-07-09 Natural Sciences Non-Clinical Trial Non-degree Award
Kirsten VanHouten
ID: UNCST-2026-R024100
 Finding Their Place: The Contributions of Women with Disabilities to Peacebuilding
REFNo: SS5277ES

1. Understand the evolution of the participation of women with disabilities in peacebuilding in relation to the emerging international inclusivity norm.
2. Document the ways that women with disabilities have exercised agency in relation to peacebuilding in hybrid settings.
3. Contribute to and extend the research of EDID-GHDI through a case study on the agency of women and girls with disabilities in peacebuilding in East Africa and thematically in relation to peacebuilding.

 Canada 2026-07-09 19:17:37 2029-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joanina Ayebare
ID: UNCST-2026-R024607
 A digital technology framework for mitigating corruption in public agencies of Uganda
REFNo: SIR678ES

1. To determine the requirements for a digital technology framework for mitigating corruption in public agencies. 2. To develop a digital technology framework for mitigating corruption in public agencies. 3. To evaluate the digital technology framework for mitigating corruption in public agencies.
Uganda 2026-07-09 19:15:07 2029-07-09 Engineering and Technology Non-Clinical Trial Degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 Halla Health Uganda – User Discovery, Co-creation and Acceptability Study
REFNo: HS7843ES

Assess the alignment of the Halla Health Alpha platform with Uganda's national health policies and digital health frameworks as evaluated by health system stakeholders. Assess the usability and trust-levels of the application among up to 60 target users and health system stakeholders. Identify contextualized iterations of the Halla Health platform for Uganda through rapid discovery and co-creation sprints. Identify the unique ECD, nutrition, and climate-sensitive health needs of young Ugandan parents.
 Uganda 2026-07-09 19:13:14 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 CONNECTING YOUTH TO GAINFUL ENTREPRENEURSHIP (Y-CONNECT) PROJECT IN NAKIVALE REFUGEE SETTLEMENT AND HOST COMMUNITIES IN ISINGIRO DISTRICT, UGANDA
REFNo: SS5438ES

Research questions

1. What is the added value of combining skilling, mentorship, and start-up capital for youth employment and income outcomes compared to capital alone?

2. Which business development support (BDS) delivery models are most effective for refugee and host youth microenterprises?

3. How does youth engagement in Village Savings and Loan Associations (VSLAs) affect resilience, social cohesion, and access to capital?

4. What role does mind-set and soft skills development play in improving entrepreneurship outcomes?

5. What characteristics define successful youth entrepreneurs in the context of Y-Connect?

 Uganda 2026-07-09 19:10:53 2029-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
 Spleen carriage of the malaria parasite, immune responses and host-parasite interactions.
REFNo: HS7898ES

The overall aims of this project are to: 1) Comprehensively map and characterize the immune landscape during malaria in spleens from currently infected and exposed individuals. 2) Identify key processes driving malaria immune development and, identify and test novel therapeutic targets and vaccine platforms that can boost immune development during infection or vaccination 3) Identify the burden of Plasmodium falciparum hidden in the spleen and conduct parasite drug sensitivity testing, phenotyping, genotyping and transcriptomic analyses to compare parasites in the spleen versus those in peripheral blood
Uganda 2026-07-09 18:53:58 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ISMAH SERUNJOJI
ID: UNCST-2026-R023494
 ENTREPRENEURIAL ORIENTATION AND INNOVATION ECOSYSTEMS IN THE INDUSTRIAL SECTOR OF KAMPALA, UGANDA
REFNo: SS5386ES

1.To examine the effect of autonomy on the innovation ecosystems of the industrial sector of Kampala, Uganda. 2.To assess the effect of innovativeness on the innovation ecosystems of the industrial sector of Kampala, Uganda. 3.To investigate the effect of risk-taking on the innovation ecosystems of the industrial sector of Kampala, Uganda. 4.To evaluate the effect of proactiveness on the innovation ecosystems of the industrial sector of Kampala, Uganda. 5.To analyse the effect of competitive aggressiveness on the innovation ecosystems of the industrial sector of Kampala, Uganda. 6.To investigate the effect of the moderating variables (Government, finance and infrastructure) on the innovation ecosystems of the industrial sector of Kampala, Uganda.
Ugandan 2026-07-09 18:50:21 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Kateregga Michael
ID: UNCST-2024-R016456
 Effects of Extreme Heat and Ambient Air Pollution on Morbidity and Mortality in Northern Uganda: A Time-Series Analysis
REFNo: HS7825ES

To assess the delayed effects of ambient temperature and PM2.5 exposure on morbidity and mortality within 0–6 days following exposure among populations in Moyo and Gulu districts, Northern Uganda, from 2015 to 2024.,To assess whether PM2.5 modifies the association between ambient temperature and morbidity and mortality among populations in Moyo and Gulu districts, Northern Uganda, from 2015 to 2024.,To assess the association between ambient PM2.5 concentrations and cardio-pulmonary morbidity and mortality among populations in Moyo and Gulu districts, Northern Uganda, from 2015 to 2024.,To determine the association between ambient temperature and all-cause morbidity and mortality among populations in Moyo and Gulu districts, Northern Uganda, from 2015 to 2024.,To assess the effects of extreme ambient temperature and ambient air pollution (PM2.5) on all-cause and cardio-pulmonary morbidity and mortality among populations in Moyo and Gulu districts, Northern Uganda, from 2015 to 2024.,
 Uganda 2026-07-09 18:49:10 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sandra Nabulega
ID: UNCST-2026-R024175
 Digital Literacy in Uganda�s Education System: Conceptualization, Enactment, and Realization Under Global Influence and Structural Inequality
REFNo: SS5413ES

To examine how digital literacy is conceptualized, enacted, and realized within Uganda�s education system under conditions of global influence and structural inequality? To analyse how digital skills are conceptualised and shaped through policy frameworks, pedagogical approaches, and learners� lived experiences in Uganda. To examine the pedagogical approaches that shape digital literacy education in Ugandan secondary schools. To examine the extent to which completion of the digital literacy course in secondary school is associated with students� perceived digital preparedness for higher education or employment.
 Uganda 2026-07-09 18:48:10 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
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