Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 6,074
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Varsha Ashok
ID: UNCST-2026-R025166
Inspiring Careers in the Agrifood Sector through Career Talks and Human-Centered Approaches
REFNo: SS5457ES

This study seeks to generate rigorous evidence to inform the design and potential scale-up of career guidance interventions for O-Level and Agricultural Technical and Vocational Education and Training (ATVET) students in Uganda’s agrifood sector. The broader project involves designing and piloting two modalities of career talks video-based and in-person using a human-centered and iterative approach. Evidence generated through the research phases will guide refinement and assess feasibility for integration into Uganda’s career guidance systems. 3.2 Research Objectives (Evidence-Generating) The research component of the study has five core objectives: To assess baseline perceptions, aspirations, and knowledge gaps among O-Level and TVET students regarding careers in Uganda’s agrifood sector. To identify key design features (content, delivery style, messenger characteristics, and format) that make career talks engaging, culturally relevant, and gender-sensitive for different student segments. To compare the effectiveness of in-person versus video-delivered career talks in influencing students’ career knowledge, perceptions, and intentions toward agrifood careers. To examine factors affecting the acceptability and feasibility of implementing career talks within school and TVET institutional contexts. To generate evidence-based recommendations for scalable career guidance interventions aligned with Uganda’s education and youth employment systems. 3.3 Project (Implementation) Objectives The following objectives relate to intervention development and implementation rather than evidence generation: To co-create career talk content with students, teachers, and agrifood professionals using a human-centered design approach. To recruit and brief role models representing selected personas for prototype development and piloting. To develop and refine prototype career talks through iterative stakeholder testing. To prepare career talk formats for potential integration into national career guidance structures. These project objectives provide the foundation for the research but are not themselves evaluative outcomes. 3.4 Research Questions What are the prevailing perceptions, aspirations, and misconceptions about agrifood careers among O-Level and TVET students in Uganda? What design elements (content, messenger, format, delivery mode) make career talks engaging and credible for students across contexts? How do in-person and video-delivered career talks differ in their influence on students’ knowledge, perceptions, and stated career intentions? What institutional, logistical, and contextual factors influence the acceptability and feasibility of delivering career talks in schools and TVET institutions? What implications do the findings have for scalable, policy-aligned career guidance interventions in Uganda?
India 2026-06-25 22:48:40 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Asiimwe Shane Ian
ID: UNCST-2024-R002876
Postpartum urinary incontinence among mothers in Kampala, Uganda: Prevalence, factors associated, lived experiences and predictors of persistence of incontinence.
REFNo: HS7886ES

4. To explore other pelvic floor dysfunctions among women with postpartum urinary incontinence in Kampala, Uganda (Sub-study IV). ,2. To establish the prevalence and the predictors of persistence of postpartum urinary incontinence among women in Kampala, Uganda (Sub study II).,2. To describe the lived experiences of women with postpartum urinary incontinence in Kampala, Uganda (Sub study II),1. To determine the prevalence and factors associated with postpartum urinary incontinence among women in Kampala, Uganda (Sub study I) ,To determine prevalence and factors associated with postpartum urinary incontinence, describe the lived experiences of affected women and establish predictors of persistence of urinary incontinence among women who have had child birth in Kampala Uganda.,
Uganda 2026-06-25 22:46:06 2029-06-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Pius Mukisa Not applicable
ID:
Lot Quality Assurance Sampling Based Surveillance of Antibiotic Use and Resistance; Stakeholder perspectives, Feasibility and Prediction of Future Resistance Risk.
REFNo: HS7718ES

1. To examine the influence of stakeholder positions, interests, incentives and power on antibiotic use (ABU) surveillance in Uganda using a political economy lens. 2. To examine the influence of stakeholder positions, interests, incentives and power on antibiotic resistance (ABR) surveillance in Uganda using a political economy lens. 3. To evaluate the acceptability, adoption, appropriateness feasibility and sustainability of lot quality assurance sampling (LQAS) based surveillance of antibiotic resistance (ABR) in Uganda 4. To determine the cost of implementing lot quality assurance sampling (LQAS) based surveillance of antibiotic resistance (ABR) at district level in Uganda. 5. To predict the future risk of developing resistance among stored extended spectrum beta lactamase producing Escherichia coli and Klebsiella pneumoniae isolates through exposure to laboratory induced selection pressures.
Uganda 2026-06-25 22:43:19 2029-06-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Cristina Reverzani
ID: UNCST-2023-R008154
Vitamin D supplementation among pregnant women in Uganda for the prevention of adverse obstetric outcomes: a randomized controlled trial
REFNo: HS7794ES

The objective of this trial is to investigate if vitamin D supplementation among pregnant women in Uganda prevents adverse maternal and foetal outcomes, with special emphasis on preeclampsia.
Italy 2026-06-25 22:39:41 2029-06-25 Medical and Health Sciences Clinical Trial Non-degree Award
Naomi Nabami
ID: UNCST-2025-R018998
Women vendors: A history of female commercial activities across the Uganda-Congo border during the 20th century.
REFNo: SS4964ES

The first objective of this project is to contribute to women’s empowerment in the subregion by looking at their historical trajectory. It will also allow for historicizing ICBT between the DRC and Uganda, recentering female agency, and bringing in the Congolese perspective. The project fills in an important blank spot in our historical understanding of the Uganda-Congo border’s economic development by connecting the precolonial, colonial, and postcolonial contexts in which this trade took place. By recentering the overlooked role of women as commercial actors throughout the history of ICBT, the project investigates how trade connections evolved in times of war and forced displacement, but also in pre-conflict decades. This will result in a dissertation that focuses on the 20th century to the present.
Here are the specific objectives of the research:
RO1 – Historicizing ICBT between the DRC and Uganda: According to Titeca (2009), informal trade activities between DRC and Uganda must be understood through the lens of a complex history that includes ethnic interconnections and refugee fluxes. Yet they also build on historical relations and exchanges that predate the context of conflict or the Structural Adjustment Programs. The project fills in an important blank spot in our historical understanding of this border’s economic development by connecting the precolonial, colonial and postcolonial contexts in which this trade took place. By recentering the overlooked role of women as commercial actors throughout the history of ICBT, the project investigates how trade connections evolved in times of war and forced displacement, but also in pre-conflict decades. This will result in a dissertation that focuses on the period 1850 to present.
RO2 – Recentering female agency: Public discourse about the border area under study, particularly the Congolese side, often portrays women as mere victims of a conflict-prone context. While sexual violence is indeed used as a weapon of war in this region, with cases dating back to colonial abuses (see Mertens 2023), it is crucial to also pay attention to the ways in which these women have shaped their livelihoods, generated forms of economic autonomy, and evaded male control (see for example Obbo 1980, MacGaffey 1988). Because of its informal character, ICBT generates specific regulatory dynamics, which not only require negotiation with state officials, but also with the broader population (see Titeca 2012). However, we know very little about the ways in which women have navigated this commercial ecosystem. Therefore, their agency is the starting point of this research project (see Thomas 2016). By applying an interdisciplinary approach and using a variety of sources, the project tackles the methodological challenges that have hitherto played a role in the overlooking of Central African female histories.
RO3 – Bringing in the Congolese perspective :Informal export from Uganda to the DRC continues to grow rapidly, with the DRC making up 49,4% of Uganda’s total informal exports in 2018, in comparison to 27,1% in 2010 (Titeca 2020: 3). While this project does not have the ambition to add quantitative data from the Congolese side to the debate, it is innovative in its historical attention to the activities, experiences and livelihoods of Congolese female experiences in this border area. The informality of their activities and the lack of control over mobility was a general source of distress for the colonial government, especially in border areas (see for example Mathys forthcoming). Recent doctoral research by Aurélie Bouvart (2024) even suggests that Congolese women who were brought to court in the Belgian Congo were mostly convicted for “crimes” related to unauthorized mobility. This project, therefore, contributes a critical new perspective by foregrounding the agency of Congolese women and by highlighting the historical continuities in their strategies for navigating both economic and social landscapes across the Congolese-Ugandan border.
Democratic Republic of Congo 2026-06-25 22:37:37 2029-06-25 Social Science and Humanities Non-Clinical Trial Degree Award
EMMANUEL OLUKA 0
ID: UNCST-2025-R022876
UNVEILING PATTERNS AND PREDICTORS OF PRE-EXPOSURE PROPHYLAXIS(PrEP) OUTCOMES AMONG PEOPLE AT HIGH RISK OF HIV IN TESO-SUBREGION, UGANDA: LATENT CLASS ANALYSIS
REFNo: HS7804ES

Objective 1: To determine the patterns of PrEP use among People at high risk of HIV in Teso sub-region using Latent class analysis Objective 2: To describe the characteristics of latent classes among different sub-groups of People at high risk to HIV Objective 3: To evaluate the class-specific PrEP outcomes among People at high risk of HIV
Uganda 2026-06-25 22:36:09 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fatumo  Segun Adeyemi
ID:
Uncovering Molecular Determinants of Complex Diseases in Africa
REFNo: HS7783ES

Aim 1: To generate broad-capture proteomic and metabolomic measurements from diverse populations in Africa. Aim 2: To utilise the genetic architecture of diverse African populations to facilitate new insights into disease pathways. Objective 2.1: Construct comprehensive molQTL maps that capture the unique genetic architecture of African populations, between African and other ancestries, and within African regions. Objective 2.2: Finemap molQTLs using high-resolution genetic data from African populations to identify causal variants Aim 3: To assess the aetiological significance of identified molecular quantitative trait loci (molQTLs) by colocalising them with complex disease-associated genetic signals. Objective 3.1: To identify shared genetic loci and perform colocalisation analysis between molQTLs and GWAS signals for complex diseases. Objective 3.2: Integrate functional annotation with pathway analysis to understand the biological mechanisms underlying colocalised loci. Objective 3.3: Identify potential drug targets and therapeutic pathways associated with prioritised colocalised loci.
UK 2026-06-25 22:34:39 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ISABIRYE PAUL
ID: UNCST-2024-R016192
An Evaluation and Adaptation of Maternal, Perinatal Death Surveillance and Response (MPDSR) in-service training and monitoring to optimise implementation in 3 rural districts of Western Uganda.
REFNo: HS7780ES

1. To conduct a scoping review of existing global literature, training evaluations, and programmatic grey materials to understand the breadth of research and identify gaps in the training of healthcare providers in MPDSR. 2. To explore and document the perspectives and experiences of health care providers, district health teams, and national -level stakeholders regarding the use of existing MPDSR training materials, training models, and monitoring tools, using a behaviour change lens, and assess the need for additional training and adaptations. 3. To adapt and optimize the MPDSR training materials based on findings from the scoping review and the qualitative assessment of stakeholder experiences, using a person -based approach. 4. To adapt and optimize the MPDSR progress-monitoring tool based on findings from the qualitative assessment of stakeholder experiences, using Think Aloud Interviews. 5. To evaluate the shifts in experiences, perceptions and practices of health workers, before and after exposure to the adapted training materials and monitoring tools and document the perceived changes and contextual influences on MPDSR implementation.
Uganda 2026-06-25 22:32:54 2029-06-25 Medical and Health Sciences Non-Clinical Trial Degree Award
JULIET BABIRYE ALLEN
ID: UNCST-2023-R005641
PROPORTION OF AND ASSOCIATED FACTORS OF OVERWEIGHT AND OBESITY AMONG ADOLESCENTS AND YOUNG PEOPLE LIVING WITH HIV IN RURAL UGANDA
REFNo: HS7728ES

We propose 1) To determine the proportion of overweight and obesity among AYLHIV in rural Uganda.2) To determine the factors associated with overweight and obesity among AYLHIV in rural Uganda. 3) To assess the facilitators and barriers of screening for overweight and obesity at the ART clinic and community distribution points in rural Uganda, and 4) To develop and internally validate a machine learning model that predicts the risk of overweight and obesity among AYLHIV in rural Uganda.
Uganda 2026-06-25 22:31:24 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MARGARET OYELA ONEGI
ID:
One-Year Post-Treatment Follow-up, Outcomes, and Determinants of Return Among Women Living with HIV Treated for Cervical Precancer in North Central Uganda
REFNo: HS7754ES

The overarching goal of this protocol is to evaluate one-year post-treatment follow-up rates, characterize clinical outcomes, and identify determinants of return among WLHIV treated for cervical precancer in North Central Uganda and the Primary Objectives are as follows:
a) To determine the proportion of WLHIV who return for the recommended one-year post-treatment rescreening after cervical precancer treatment.
b) To assess the clinical outcomes, such as persistent disease, among WLHIV who return for the one-year post-treatment rescreening.
c) To identify individual, clinical, and health system factors associated with returning for the one year post treatment rescreening among WLHIV

Uganda 2026-06-25 22:27:43 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
OCEN WALTER
ID: UNCST-2026-R024230
PERCEPTION OF COFFEE FARMERS ON THE DISTRIBUTION, MANAGEMENT AND EFFECTS OF DODDER WEED (CUSCUTA REFLEXA) ON COFFEE PRODUCTION IN LIRA DISTRICT, UGANDA.
REFNo: A777ES

1. To determine the farmers perception on the distribution and abundance of C. reflexa on coffee plantations. 2. To determine coffee farmers perception on management practices of C. reflexa 3. To determine coffee farmers risks that arise from C. reflexa infestation.
Uganda 2026-06-25 22:23:57 2029-06-25 Agricultural Sciences Non-Clinical Trial Degree Award
Dorothy Akongo
ID: UNCST-2023-R007564
Evaluating Essential Services provided by the Local Governments Using Citizen Report Card Endline Survey in Jinja, Uganda
REFNo: SS5329ES

1. To assess the citizens' knowledge and participation in the services provided by their local
government besides health.
2. To assess the community understanding and awareness of child focused health care and the right
of the child within the health care system
3. To explore health care providers’, children and community members understanding of child rights,
experiences and participation in health care received at health facilities and local government
Uganda 2026-06-25 22:22:13 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Walakira
ID: UNCST-2025-R022446
Combating Antimalarial Resistance: An AI-Driven Approach to Identify andPrioritize Key Parasite Mutations
REFNo: HS7367ES

1. To use AI-driven variant prediction, structural modeling, and clinical-epidemiological data integration to identify and prioritize Plasmodium falciparum mutations associated with drug and vaccine resistance.

2. To predict the pathogenicity of mutations across the P. falciparum genome.

3. To identify mutations located in active or functionally critical regions of prioritized P. falciparum genes by applying variant effect prediction and protein structure modeling tools.

4. To link predicted pathogenic mutations with available epidemiological and clinical metadata to identify variants of public health importance, including those associated with treatment failure, disease severity, or vaccine response.
Uganda 2026-06-25 22:18:53 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
Evaluation of the Uzazi Salama Project on Healthy Pregnancies and Climate Resilience among Adolescent Girls and Young Women (AGYW) in Kasese district.
REFNo: SS5254ES

Primary objective:
To generate evidence on the maternal health journey of pregnant AGYW and assess health system readiness to provide quality maternal care and access health system readiness to provide quality maternal care for AGYWs in climate affected settings.
1. To assess health system readiness to provide quality youth friendly maternal health services for adolescence girls and young women in climate affected settings
2. To explore social cultural, economic and gender-related barriers influencing AGYWs access to sexual and reproductive health and maternal health services.
3. To document AGYW experiences using a journey mapping approach.
4. To assess the impact of climate related shocks (floods, landslides, droughts etc.) on access and utilization of maternal health services.
5. To identify health system challenges affecting quality of care and influence access to and utilization of maternal health care services among adolescent girls and young women (AGYWs).
6. To generate evidence to inform co design of climate resilient interventions

Uganda 2026-06-25 22:17:28 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Julius Monday Rude
ID: UNCST-2025-R019646
Transmission Dynamics, Risk Factors, and Clinical Outcomes of Monkeypox Virus in Uganda from 2024 to 2025
REFNo: HS7965ES

1. To identify the risk factors of MPXV infection in Central and Western Uganda between 2024 and 2025. 2. To assess the routes of transmission of MPXV infection among adults in Central and Western Uganda between 2024 and 2025. 3. To assess the clinical presentation of MPXV infection among hospitalized adults in Central and Western Uganda between 2024 and 2025. 4. To assess the clinical outcomes of MPXV infection among hospitalized adults in Central and Western Uganda between 2024 and 2025. 5. To explore the three-month post-recovery effects of MPXV infection based on experiences of adult survivors of Mpox in communities of Central and Western Uganda between 2024 and 2025.
Uganda 2026-06-25 22:15:25 2029-06-25 Medical and Health Sciences Non-Clinical Trial Degree Award
John Okumu Bismarck
ID: UNCST-2025-R021281
An Exploration of the Effect of the Lower Secondary Competency-Based Curriculum on Lifelong Learning in Acholi subregion, Northern Uganda
REFNo: SS5199ES

Purpose To generate context specific evidence on how the implementation of the Lower Secondary Competency Based Curriculum contributes to the development of Lifelong Learning competencies among learners in the Acholi sub-region, Northern Uganda Specific Objectives The study will be guided by the following objectives: 1. To explore the Competency-Based Curriculum teaching/learning practices that align to lifelong learning in lower secondary schools in Acholi sub-region of Northern Uganda 2. To assess the indicators of lifelong learning on the students engaged in Competency-Based Curriculum in Acholi Sub-region of Northern Uganda 3. To explore experiences of stakeholders (Headteachers, Directors of studies, teachers and students) with CBC policy implementation in lower secondary schools in Acholi sub-region of Northern Uganda. 4. To analyse challenges in the implementation of the Competency-Based Curriculum in lower secondary schools in Acholi sub-region of Northern Uganda.
Uganda 2026-06-25 22:11:20 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Wandera Yusuf
ID: UNCST-2026-R024024
"GOVERNANCE PRACTICES, FINANCIAL LITERACY PROGRAMS, AND EQUITABLE MEMBER DEVELOPMENT IN RURAL UGANDA SACCOS"
REFNo: SS5278ES

1. To assess how the effectiveness of SACCO leadership and board governance influences equitable member development.
2. To evaluate the role of transparency and accountability in promoting trust and fair distribution on equitable member development.
3. To examine the extent to which member involvement in SACCO governance affects equitable member development.
4. To investigate the impact of adherence to SACCO governance internal controls and risk management on equitable member development.
5. To evaluate how financial literacy programs affect equitable member development.
6. To develop evidence-based policy recommendations aimed at strengthening governance practices and financial literacy frameworks to enhance equitable member development in rural Uganda SACCOs.

Uganda 2026-06-25 22:09:43 2029-06-25 Social Science and Humanities Non-Clinical Trial Degree Award
WINNIE ACHOLA STELLA
ID: UNCST-2026-R024263
IMPACT OF STONE QUARRYING ACTIVITIES ON AIR, WATER QUALITY AND ASSOCIATED SELF-REPORTED RESPIRATORY SYMPTOMS: A CASE STUDY OF TE-DAM STONE QUARRY SITE IN GULU CITY
REFNo: NS1272ES

1. To determine the concentrations of particulate matter (PM10 and PM2.5) at varying distances from selected stone quarry sites in Te-dam. 2. To determine the physicochemical parameters (pH, turbidity, total dissolved solids, total suspended solids, nitrates, nitrites, iron, and color) of the surface water near Te-Dam quarry site. 3. To assess the perceived respiratory and water related health effects associated with air and water quality deterioration resulting from stone quarrying activities on individuals around Te Dam.
Uganda 2026-06-25 22:04:22 2029-06-25 Natural Sciences Non-Clinical Trial Degree Award
BOSCO Opio
ID: UNCST-2026-R023988
Modelling Seasonal Variations and the Influence of Personal-Environmental characteristics on Malaria Risk: Evidence from Lira District
REFNo: NS1304ES

Main Objective
To investigate the seasonal variations in malaria incidence and assess the influence of personal and
environmental characteristics on malaria risk in Lira District.
1.3.1 Specific Objectives
1. To Examine the seasonal variations of Malaria incidence in Lira district.
2.To Determine the influence of personal and environmental factors on the risk of malaria among
individuals in Lira District.
3. To Establish a suitable model to predict malaria risk in Lira district.
Uganda 2026-06-25 22:02:25 2029-06-25 Natural Sciences Non-Clinical Trial Degree Award
Futoshi Yamauchi
ID: UNCST-2026-R025076
Impacts of Solar Lanterns on Child Learning and Livelihoods in Refugee Camps and Hosting Communities in Northern Uganda: Incentives, Heterogeneity, and the Intrahousehold Allocation of Time
REFNo: SS5315ES


Japan 2026-06-25 22:00:31 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."