Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Eve  Namisango
ID: UNCST-2021-R014038
 Piloting the use of sub-Saharan Africa spirituality guidelines and standards to support the integration of spirituality care into routine palliative care services at Kitovu Mobile hospice
REFNo: SS5371ES

2) To build a core team of palliative care and community health workers trained in generalist spiritual care ,1) To co-design a strategy for integrating spiritual care into routine palliative care services at Kitovu Mobile,To undertake a demonstration project on how to integrate spiritual care into routine palliative care leveraging evidence-based recommendations and standards alongside appropriate measures for assessment, management/support and measuring outcomes,
 Uganda 2026-06-05 16:41:18 2029-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Development of Host Biomarker-Guided Approaches to Mitigate Endemic and Emerging Biothreats
REFNo: HS7512ES

To conduct comprehensive host transcriptomic and proteomic profiling of biospecimens previously collected under IRB approved protocols meeting clinical definitions of the syndromes Pneumonia, Acute Respiratory Distress Syndrome, Sepsis and Meningoencephalitis
 Uganda 2026-06-05 16:30:22 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Katumba
ID:
Local Validation and Calibration Assessment of the CerviCARE Artificial Intelligence Cervicography Tool Within Routine VIA-Based Cervical Cancer Screening in Uganda: A Mixed-Methods Study with Comparative Patient and Provider Experience Assessment
REFNo: HS7752ES

Primary objective: To compare the diagnostic performance of the CerviCARE AI tool with VIA performed by experienced screening midwives and healthcare workers within routine cervical cancer screening services at the Uganda Cancer Institute and its affiliated satellite site in Mbarara, and to characterise the tool’s agreement, calibration and operational performance within routine service delivery. Secondary objectives 1. To assess the quality-assurance performance of CerviCARE using colposcopy-directed biopsy and histopathological confirmation among a targeted subset of approximately 180 participants with abnormal, suspicious, borderline or discordant screening findings within the 1,500-woman validation cohort. 2. To assess and compare patient and healthcare provider experiences of routine VIA-based cervical cancer screening delivered with and without CerviCARE support, including understanding of results, communication, acceptability, trust, dignity, workflow, provider confidence and perceived usefulness within routine service delivery. 3. To quantify inter-observer variability in VIA interpretation among study providers and to assess how CerviCARE outputs align with consensus VIA and histology in discordant cases.
 Uganda 2026-06-05 16:26:45 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 Efficacy of a High-Calorie High-Protein Supplement on Weight for Age and Mid Upper Arm Circumference of Children with Special Needs in Uganda
REFNo: HS7734ES

Assess caregiver knowledge, attitudes and practices regarding the preparation, use and perceived benefits of the supplement,Assess the effect of the supplement on weight for age and mid upper arm circumference among children with CP,To analyze the nutrient composition of the 1-week pureed food menu provided at the orphanage using the MyDietAnalysis program to determine its adequacy in meeting the nutritional requirements of the children.,Develop an energy-protein dense supplement to improve nutritional status of children with Celebral Palsy and other disabilities.,To test the efficacy of a sustainable high-calorie, high-protein supplement in therapeutic care of malnourished Ugandan children with disabilities. ,
 Uganda 2026-06-05 16:24:12 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Max Bobholz
ID: UNCST-2025-R021763
 Health-related quality of life and environmental distress among climate-displaced communities in Uganda
REFNo: HS7560ES

4.1. General Objective
The general objective of this study is to characterize, summarize, and explore the connection between CRD and the current health-related QoL and environmental distress circumstances of CRMs in Uganda, focusing on both the national level and within a single IDP camp.


4.2. Specific Objectives
We propose two specific objectives that run in parallel to one another.
Objective 1: Characterize key stakeholders’ understanding of the causes and health-related consequences of CRD in Uganda. This objective will investigate stakeholders’ understanding of CRM circumstances in Uganda, particularly the types of climate factors contributing to displacement, the challenges faced by this population, and potential strategies for improving their health, using key informant interviews.
Objective 2: Explore how climate-related displacement experiences, aspects of vulnerability, and resilience contribute to quality of life and environmental distress (e.g., solastalgia and loss of place) throughout migration journeys of climate-related migrants in the Muhokya IDP Camp in Kasese District. Guided by an emerging method that blends geospatial mapping and narrative analysis,20 we will qualitatively explore the displacement, QoL, and distress experiences of CRMs.

 USA 2026-06-05 16:22:02 2029-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Kembabazi Juliet
ID: UNCST-2025-R017646
 EMPLOYEE PERCEPTIONS OF ATTRACTION AND RETENTION IN PRIVATE UNIVERSITIES IN UGANDA. A CASE OF PRIVATE CHARTERED UNIVERSITIES IN WESTERN UGANDA
REFNo: SS5050ES

THE STUDY AIMS AT EXAMINING HOW EMPLOYEE PERCEPTIONS INFLUENCE ATTRACTION AND RETENTION OF EMPLOYEES IN PRIVATE UNIVERSITIES IN WESTERN UGANDA
Uganda 2026-06-05 16:19:37 2029-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
NSUBUGA GERALD
ID: UNCST-2021-R011633
 Feasibility and Acceptability Using Umbilical Cord Blood for Cancer Treatment through Stem Cell Transplantation: A Multi-Center Study Involving Pregnant Mothers, Health Workers, and Cancer Patients in Collaboration with the Uganda Blood Transfusion Service
REFNo: HS6131ES

General Objective To assess the feasibility and acceptability of collecting and using umbilical cord blood for stem cell transplantation in cancer patients based on the perceptions and readiness of pregnant mothers, health professionals, and cancer patients in selected public health facilities in Uganda. Specific Objectives 1. To determine the level of awareness and knowledge about umbilical cord blood stem cell transplantation among pregnant mothers, health professionals, and cancer patients. 2. To assess the willingness of pregnant mothers to donate umbilical cord blood for therapeutic use. 3. To evaluate the preparedness of health professionals to support UCB collection, processing, and utilization.
Uganda 2026-06-05 15:35:56 2029-06-05 Medical and Health Sciences Clinical Trial Non-degree Award
Begumisa Godfrey Magyezi
ID: UNCST-2024-R002711
 Remediation of Schistosome cercaria and fecal bacteria from contaminated water sources using a constructed wetland and Electrochlorination
REFNo: NS1253ES

3. To determine the enhancement potential of the sequential vertical flow CW and EC in treatment of water contaminated with schistosome cercariae and fecal indicator bacteria,2. To determine the best practices of a vertical flow constructed wetland for schistosome cercariae and fecal contamination indicator bacteria removal,1. To establish the best practices of EC application for schistosome cercaria and fecal indicator bacteria disinfection ,To investigate the best practices for schistosome cercariae and fecal bacteria remediation from polluted water sources of the schistosomiasis hot spot region of Lake Albert, western Uganda,
 Uganda 2026-06-01 18:19:31 2029-06-01 Natural Sciences Degree Award
Drake Musoki
ID: UNCST-2026-R023417
 Assessing Usability and Patient preferences of the Validated Luganda Self-Reporting Questionnaire (SRQ-20) among PLHIV in Uganda.
REFNo: HS7482ES

General Objective To Assess the Usability and Patient Preferences of the Validated Luganda Self-Reporting Questionnaire (SRQ-20) among PLHIV attending Mildmay Hospital, Uganda. Specific Objectives 1. To assess Usability of the Luganda SRQ-20 by evaluating the comprehension, ease of use and completion time among PLHIV. 2. To explore patient preferences by identifying the desired mode of delivery mode (self vs health-worker administered). 3. To determine the perceived barriers and necessary adaptations to make the SRQ-20 accessible to diverse PLHIV populations (i.e. with disabilities, low literacy levels, urban vs rural).
 Uganda 2026-06-01 18:18:14 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Okeny
ID: UNCST-2021-R012931
 The PARSNIP Study PREVALENCE AND FACTORS ASSOCIATED WITH LOW ANTERIOR RESECTION SYNDROME AND QUALITY OF LIFE AMONG PATIENTS UNDERGOING SURGERY FOR RECTAL CANCER IN UGANDA.
REFNo: HS7451ES

Aim 1
To determine the prevalence and factors associated with low anterior resection syndrome (LARS) among patients undergoing low anterior resection for rectal cancer in Uganda.
Specific Objectives
1. To determine the prevalence of Low Anterior Resection Syndrome among patients who have had low anterior resection for rectal cancer in Mulago Hospital.
2. To describe factors associated with Low Anterior Resection Syndrome among patients who have had low anterior resection for rectal cancer in Mulago Hospital.
Aim 2
To evaluate the health-related quality of life and factors associated with a poor quality of life among patients who have had surgical resection for rectal cancer in Uganda.
Specific objectives
1. To determine the quality of life of patients who have had surgical resection for rectal cancer in Mulago Hospital.
2. To assess the factors associated with a poor quality of life following surgical resection for rectal cancer in Mulago Hospital.

 Uganda 2026-06-01 18:15:40 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Mugonya
ID: UNCST-2025-R018082
 DETERMINANTS OF PARTICIPATION OF SMALLHOLDER COFFEE FARMERS IN THE AGROFORESTRY CARBON REMOVAL BUSINESS
REFNo: A753ES

- To examine the factors that influence the participation of smallholder coffee agroforestry farmers in the Voluntary Carbon Market (VCM) -To characterise business models for agroforestry carbon projects across a context and mechanisms continuum - To assess the perceptions of smallholder coffee-agroforestry farmers of benefits and constraints associated with participating in carbon projects - To examine the implementation mechanisms of carbon projects within smallholder coffee agroforestry sector in Uganda - To establish a multi-stakeholder co-design process for prototyping inclusive business models for agroforestry ecosystem services among smallholder coffee farmers in Uganda
 Uganda 2026-06-01 18:13:55 2029-06-01 Agricultural Sciences Non-Clinical Trial Degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Mobile Phone Surveys for NCD Risk Factor Estimation in Uganda
REFNo: HS7319ES

Objective 1: Compare IVR and computer assisted telephone interviews (CATI) performances.
Objective 2: Optimize urban/rural questions to better triangulate residences in urban and rural areas.
Objective 3: Better understand interactive voice response (IVR) disposition codes generated by IVR platforms and services to improve response rate.
 Uganda 2026-06-01 18:12:47 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FELIX YETUNGYE KAMUHANDA
ID: UNCST-2026-R023493
 Enhancing childhood cancer outcomes in southwestern Uganda: Addressing diagnostic and treatment delays, and describing a patient cohort at the Mbarara Regional Referral Hospital
REFNo: HS7579ES

The overarching objective is to improve timely diagnosis and treatment, and outcomes for childhood cancer patients in southwestern Uganda by characterizing childhood cancer patients seen at the Paediatric Cancer unit (PCU) in MRRH, assessing the diagnostic pathways and delays, capturing experiences of caretakers and key stakeholders, and developing a context-specific referral algorithm supported by quality paediatric cancer data. The specific objectives include: 1. To characterize the cohort of childhood cancer patients presenting to the PCU (including sociodemographic, symptom progression, clinical presentation at PCU, cancer types, diagnostics, treatments, and outcomes) using a validated database. 2. To describe the patient journey and delays at each stage of the three delays model (detailed in the figure 1) with a focus on: a. Quantifying the average time intervals (delays) from symptom onset to confirmed diagnosis and treatment initiation of common childhood cancers, and to describe the implications of these delays on the outcomes of the patient cohort. b. Describing the healthcare pathways and determining factors associated with duration of delays for common childhood cancers. c. Exploring the lived experiences of caretakers of children diagnosed with cancer, from initial symptom recognition to diagnosis and treatment initiation. d. Exploring the perceptions of key stakeholders (including healthcare providers at all levels of the healthcare system and key community informants) on childhood cancer and on its diagnosis and treatment initiation delays. 3. To collaboratively develop and refine context-specific referral decision algorithms for childhood cancers to improve early identification and referral efficiency.
Uganda 2026-06-01 18:09:54 2029-06-01 Medical and Health Sciences Non-degree Award
Simon  ACHUU Peter
ID: UNCST-2025-R017228
 Impact of Climate Variability on Rangelands Ecosystems Productivity and Mitigation Measures in Awoja Catchment Area, Eastern Uganda
REFNo: NS1255ES

1. To analyze the relationship between climate variability and rangeland ecosystem productivity patterns in the Awoja catchment area between 1984 and 2024.
2. To examine community perceptions on the impacts of climate variability on rangelands ecosystem productivity in the Awoja catchment area.
3. To examine the effectiveness of existing community based copying strategies to mitigate negative impacts of climate variability on rangeland ecosystem productivity in Awoja catchment area.
4. To design and test selected ecosystem based adaptation-EbA techniques in maintaining rangeland ecosystem productivity under climate variability scenario in Awoja catchment area.

 Uganda 2026-06-01 18:08:07 2029-06-01 Natural Sciences Non-Clinical Trial Degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 Extended monitoring of HIV status and vaccine-induced seropositivity among PrEPVacc trial participants (PrEPVacc Extension Study).
REFNo: HS7676ES

1. To provide comprehensive HIV testing and counseling services to PrEPVacc trial participants, including virus detection and prevention of the misdiagnosis of HIV infection among individuals with VISP.
2. To facilitate and support participants who wish to take up PrEP to reduce their risk of acquiring HIV.
3. To facilitate linkage to care for participants who acquire HIV and support their timely initiation of antiretroviral therapy.
4. To explore participants’ and trial staff’s reflections on trial participation and outcomes, including their lived experiences of VISP and perceptions of oral PrEP offered within the trial.

Uganda 2026-06-01 18:05:24 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arthur Sekiziyivu
ID: UNCST-2026-R023989
 EVALUATION of HEALTH CARE WORKERS’ ADHERENCE to MALARIA CASE MANAGEMENT GUIDELINES (HAMG) IN MAYUGE DISTRICT.
REFNo: HS7648ES

Aim 1: To assess HCWs’ adherence to the 2023 UCG in the treatment of patients with confirmed uncomplicated malaria at Mayuge HC IV for the three months preceding this study, and the facility-level factors that influence adherence. Aim 2: To explore behavioural determinants of HCWs’ adherence to the 2023 UCG in the treatment of uncomplicated malaria at Mayuge Health Centre IV. Aim 3: To develop an implementation strategy aimed at improving HCWs’ adherence to the 2023 UCG in the treatment of uncomplicated malaria in Mayuge District.
Uganda 2026-05-28 17:53:46 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Ainembabazi Hebert
ID: UNCST-2026-R024520
 Reducing Food Loss and Waste of Fruits and Vegetables in Uganda’s Food Markets
REFNo: A760ES

Reduce post harvest losses of fruits and vegetables among retail traders in Kampala markets through access to cold storage services
 Uganda 2026-05-28 16:53:16 2029-05-28 Agricultural Sciences Non-Clinical Trial Non-degree Award
Gertrude Nakigozi
ID: UNCST-2025-R022719
 The Many faces of Trauma and Recovery around the World: Mapping Experiences in Cultural Context (Matrix) Pilot Study
REFNo: HS7621ES

1. Assess the cultural relevance, feasibility and acceptability of the study design and instruments (survey and in-depth interview questionnaire) to inform implementation feasibility in Phase II of the project. 2. Preliminarily explore cross-cultural experiences of traumatic events, including individual psychological and somatic responses to PTEs, their perceived causes, approaches to coping and healing, subjective wellbeing and functioning, and the role of culture, context and identity. 3. Identify cross-cultural conceptualizations and expressions of trauma, including convergences and divergences in traumatic experiences, trauma sequelae, idioms of distress, and cultural scripts, their subjective interpretation and the meaning attributed to these. 4. Investigate culturally-specific healing and coping strategies, including individualistic vs collective approaches.
Uganda 2026-05-28 16:43:56 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
 UCatchUp cost-effectiveness evaluation
REFNo: SS5226ES

Understand the potential to scale up the UCatchUp program,
 Uganda 2026-05-28 16:42:20 2029-05-28 Social Science and Humanities Non-degree Award
Florence Kyoheirwe Muhanguzi
ID: UNCST-2021-R002777
 Climate Resilience Solutions in the West Nile Region of Uganda (CARIS)
REFNo: SS5142ES

The primary objective of CARIS is to investigate the complex interplay of hydrological, ecological, and socioeconomic factors in the West Nile region of Uganda, focusing on the Enyau River catchment within the context of climate change.
Uganda 2026-05-28 16:39:51 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
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