Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Japheth Noel
ID: UNCST-2021-R013959
 Refugee Students in Uganda’s Higher Education System: A Grounded Theory Study on Conditions for Successful Integration
REFNo: SS5259ES

The main objective of the study is to develop a theoretical model for successful integration of refugee students in the Ugandan higher education system that is based on the attributes, perspectives, experiences and strategies(enablers) and constraints(disablers) for their access, participation and success in Ugandan higher education system.
Uganda 2026-06-11 12:12:13 2029-06-11 Social Science and Humanities Non-Clinical Trial Degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 Formative Usability Study Protocol of the Panbio™ Dengue Duo test with Fingerstick Sample Collection
REFNo: HS7731ES

The primary objectives of this usability study are
• To evaluate Health Care Professional users’ Panbio™ Dengue Duo test labelling comprehension and the usability of the supplied components as describe in the IFU in a Point of Care setting. This will be assessed through the user questionnaire and observation sheets.
• To assess which lancet generates the correct volume of blood to enable to user to collect two samples from the same fingerstick.
• To identify the optimal instruction and technique for using the plastic capillary tube to collect the 30 µL from a fingerstick and to understand the impact of fingerstick on the usability of the sample collection tools.

 Uganda 2026-06-11 12:06:13 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
 Learning together to advance Evidence and Equity in Policymaking to achieve the SDGs in Africa (Africa LEEPS)
REFNo: SS5344ES

The overall objective is to strengthen evidence pathways at regional and national levels to ensure timely access to relevant, contextualized evidence, including gender analysis, for policymaking that enhances population wellbeing.,4. To build a culture of sustained evaluation, knowledge exchange, and learning within the LEEPS partnership and the partners within the EARESI. ,3. To design a platform structures and processes to support timely access and use of evidence response at regional level for gender equity and inclusion in policymaking to enhance population wellbeing.,2. To strengthen the sustained capacity of individuals and organisations in applying evidence and gender equity and inclusion in policymaking to enhance population wellbeing,1. To strengthen evidence pathways at a regional policymaking to strengthen timely access to relevant and contextualised evidence, including gender analysis, for informing decisions to enhance population wellbeing,
 Uganda 2026-06-11 12:04:48 2029-06-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Platform Adaptive Randomised Trial for NEw and Repurposed Filovirus treatmentS
REFNo: HS7849ES

To evaluate the impact of potential treatments on mortality in patients with filovirus disease. ,
 Uganda 2026-06-08 21:31:41 2029-06-08 Medical and Health Sciences Clinical Trial Non-degree Award
Derrick Abila Bary
ID: UNCST-2020-R014563
 Feasibility, acceptability, and preliminary outcomes of childhood cancer survivor-delivered nurse-facilitated peer support model on anxiety and depression among adolescents newly diagnosed with cancer at Uganda Cancer Institute (UCI), Uganda
REFNo: HS7533ES

1) To co-design with stakeholders the TOGETHER implementation strategies for adolescents newly diagnosed with cancer at UCI, Uganda,To evaluate the feasibility, acceptability, appropriateness, and preliminary outcomes of TOGETHER (a peer-support intervention delivered by childhood cancer survivors and nurse facilitators) on anxiety and depression among adolescents newly diagnosed with cancer at the Uganda Cancer Institute (UCI). 2) To pilot test the TOGETHER implementation strategies among adolescents newly diagnosed with cancer at UCI, Uganda, using a hybrid type II effectiveness implementation trial design. 3) To assess the perceived barriers and facilitators of a childhood cancer survivor (CCS) delivered nurse-facilitated peer support model (TOGETHER) for adolescents newly diagnosed with cancer at UCI, Uganda.
 Uganda 2026-06-08 16:16:30 2029-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Derrick Abila Bary
ID: UNCST-2020-R014563
 COMPARATIVE STUDY OF THE CERVICAL CANCER SCREENING FOR PREVENTION AND CONTROL PROGRAM: A CASE OF MBARARA MBARARA/CITY VS GULU DISTRICT/CITY
REFNo: HS7800ES

Main Objective
1. To evaluate the effectiveness of cervical cancer screening interventions at intervention sites compared with control sites in Gulu City and Gulu District during the same period.

Specific Objectives
1. To determine the number and proportion of precancerous lesions detected among women screened for cervical cancer in the intervention sites and compare these with the control sites.
2. To compare screen-positive treatment rates in the intervention and control sites before and after the intervention.
3. To assess the investments (costs) made to facilitate cervical cancer screening in the intervention sites compared with the control sites.
4. To compare the level of cervical cancer knowledge, awareness, and practices between the women in the communities in the intervention and control sites.
5. To explore stakeholder perspectives on the implementation, acceptability, barriers, facilitators, and sustainability of cervical cancer screening service delivery in the intervention and control sites.
 Uganda 2026-06-08 16:04:57 2029-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Piloting the use of sub-Saharan Africa spirituality guidelines and standards to support the integration of spirituality care into routine palliative care services at Kitovu Mobile hospice
REFNo: SS5371ES

2) To build a core team of palliative care and community health workers trained in generalist spiritual care ,1) To co-design a strategy for integrating spiritual care into routine palliative care services at Kitovu Mobile,To undertake a demonstration project on how to integrate spiritual care into routine palliative care leveraging evidence-based recommendations and standards alongside appropriate measures for assessment, management/support and measuring outcomes,
 Uganda 2026-06-05 16:41:18 2029-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Development of Host Biomarker-Guided Approaches to Mitigate Endemic and Emerging Biothreats
REFNo: HS7512ES

To conduct comprehensive host transcriptomic and proteomic profiling of biospecimens previously collected under IRB approved protocols meeting clinical definitions of the syndromes Pneumonia, Acute Respiratory Distress Syndrome, Sepsis and Meningoencephalitis
 Uganda 2026-06-05 16:30:22 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Katumba
ID:
Local Validation and Calibration Assessment of the CerviCARE Artificial Intelligence Cervicography Tool Within Routine VIA-Based Cervical Cancer Screening in Uganda: A Mixed-Methods Study with Comparative Patient and Provider Experience Assessment
REFNo: HS7752ES

Primary objective: To compare the diagnostic performance of the CerviCARE AI tool with VIA performed by experienced screening midwives and healthcare workers within routine cervical cancer screening services at the Uganda Cancer Institute and its affiliated satellite site in Mbarara, and to characterise the tool’s agreement, calibration and operational performance within routine service delivery. Secondary objectives 1. To assess the quality-assurance performance of CerviCARE using colposcopy-directed biopsy and histopathological confirmation among a targeted subset of approximately 180 participants with abnormal, suspicious, borderline or discordant screening findings within the 1,500-woman validation cohort. 2. To assess and compare patient and healthcare provider experiences of routine VIA-based cervical cancer screening delivered with and without CerviCARE support, including understanding of results, communication, acceptability, trust, dignity, workflow, provider confidence and perceived usefulness within routine service delivery. 3. To quantify inter-observer variability in VIA interpretation among study providers and to assess how CerviCARE outputs align with consensus VIA and histology in discordant cases.
 Uganda 2026-06-05 16:26:45 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 Efficacy of a High-Calorie High-Protein Supplement on Weight for Age and Mid Upper Arm Circumference of Children with Special Needs in Uganda
REFNo: HS7734ES

Assess caregiver knowledge, attitudes and practices regarding the preparation, use and perceived benefits of the supplement,Assess the effect of the supplement on weight for age and mid upper arm circumference among children with CP,To analyze the nutrient composition of the 1-week pureed food menu provided at the orphanage using the MyDietAnalysis program to determine its adequacy in meeting the nutritional requirements of the children.,Develop an energy-protein dense supplement to improve nutritional status of children with Celebral Palsy and other disabilities.,To test the efficacy of a sustainable high-calorie, high-protein supplement in therapeutic care of malnourished Ugandan children with disabilities. ,
 Uganda 2026-06-05 16:24:12 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Max Bobholz
ID: UNCST-2025-R021763
 Health-related quality of life and environmental distress among climate-displaced communities in Uganda
REFNo: HS7560ES

4.1. General Objective
The general objective of this study is to characterize, summarize, and explore the connection between CRD and the current health-related QoL and environmental distress circumstances of CRMs in Uganda, focusing on both the national level and within a single IDP camp.


4.2. Specific Objectives
We propose two specific objectives that run in parallel to one another.
Objective 1: Characterize key stakeholders’ understanding of the causes and health-related consequences of CRD in Uganda. This objective will investigate stakeholders’ understanding of CRM circumstances in Uganda, particularly the types of climate factors contributing to displacement, the challenges faced by this population, and potential strategies for improving their health, using key informant interviews.
Objective 2: Explore how climate-related displacement experiences, aspects of vulnerability, and resilience contribute to quality of life and environmental distress (e.g., solastalgia and loss of place) throughout migration journeys of climate-related migrants in the Muhokya IDP Camp in Kasese District. Guided by an emerging method that blends geospatial mapping and narrative analysis,20 we will qualitatively explore the displacement, QoL, and distress experiences of CRMs.

 USA 2026-06-05 16:22:02 2029-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Kembabazi Juliet
ID: UNCST-2025-R017646
 EMPLOYEE PERCEPTIONS OF ATTRACTION AND RETENTION IN PRIVATE UNIVERSITIES IN UGANDA. A CASE OF PRIVATE CHARTERED UNIVERSITIES IN WESTERN UGANDA
REFNo: SS5050ES

THE STUDY AIMS AT EXAMINING HOW EMPLOYEE PERCEPTIONS INFLUENCE ATTRACTION AND RETENTION OF EMPLOYEES IN PRIVATE UNIVERSITIES IN WESTERN UGANDA
Uganda 2026-06-05 16:19:37 2029-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
NSUBUGA GERALD
ID: UNCST-2021-R011633
 Feasibility and Acceptability Using Umbilical Cord Blood for Cancer Treatment through Stem Cell Transplantation: A Multi-Center Study Involving Pregnant Mothers, Health Workers, and Cancer Patients in Collaboration with the Uganda Blood Transfusion Service
REFNo: HS6131ES

General Objective To assess the feasibility and acceptability of collecting and using umbilical cord blood for stem cell transplantation in cancer patients based on the perceptions and readiness of pregnant mothers, health professionals, and cancer patients in selected public health facilities in Uganda. Specific Objectives 1. To determine the level of awareness and knowledge about umbilical cord blood stem cell transplantation among pregnant mothers, health professionals, and cancer patients. 2. To assess the willingness of pregnant mothers to donate umbilical cord blood for therapeutic use. 3. To evaluate the preparedness of health professionals to support UCB collection, processing, and utilization.
Uganda 2026-06-05 15:35:56 2029-06-05 Medical and Health Sciences Clinical Trial Non-degree Award
Begumisa Godfrey Magyezi
ID: UNCST-2024-R002711
 Remediation of Schistosome cercaria and fecal bacteria from contaminated water sources using a constructed wetland and Electrochlorination
REFNo: NS1253ES

3. To determine the enhancement potential of the sequential vertical flow CW and EC in treatment of water contaminated with schistosome cercariae and fecal indicator bacteria,2. To determine the best practices of a vertical flow constructed wetland for schistosome cercariae and fecal contamination indicator bacteria removal,1. To establish the best practices of EC application for schistosome cercaria and fecal indicator bacteria disinfection ,To investigate the best practices for schistosome cercariae and fecal bacteria remediation from polluted water sources of the schistosomiasis hot spot region of Lake Albert, western Uganda,
 Uganda 2026-06-01 18:19:31 2029-06-01 Natural Sciences Degree Award
Drake Musoki
ID: UNCST-2026-R023417
 Assessing Usability and Patient preferences of the Validated Luganda Self-Reporting Questionnaire (SRQ-20) among PLHIV in Uganda.
REFNo: HS7482ES

General Objective To Assess the Usability and Patient Preferences of the Validated Luganda Self-Reporting Questionnaire (SRQ-20) among PLHIV attending Mildmay Hospital, Uganda. Specific Objectives 1. To assess Usability of the Luganda SRQ-20 by evaluating the comprehension, ease of use and completion time among PLHIV. 2. To explore patient preferences by identifying the desired mode of delivery mode (self vs health-worker administered). 3. To determine the perceived barriers and necessary adaptations to make the SRQ-20 accessible to diverse PLHIV populations (i.e. with disabilities, low literacy levels, urban vs rural).
 Uganda 2026-06-01 18:18:14 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Okeny
ID: UNCST-2021-R012931
 The PARSNIP Study PREVALENCE AND FACTORS ASSOCIATED WITH LOW ANTERIOR RESECTION SYNDROME AND QUALITY OF LIFE AMONG PATIENTS UNDERGOING SURGERY FOR RECTAL CANCER IN UGANDA.
REFNo: HS7451ES

Aim 1
To determine the prevalence and factors associated with low anterior resection syndrome (LARS) among patients undergoing low anterior resection for rectal cancer in Uganda.
Specific Objectives
1. To determine the prevalence of Low Anterior Resection Syndrome among patients who have had low anterior resection for rectal cancer in Mulago Hospital.
2. To describe factors associated with Low Anterior Resection Syndrome among patients who have had low anterior resection for rectal cancer in Mulago Hospital.
Aim 2
To evaluate the health-related quality of life and factors associated with a poor quality of life among patients who have had surgical resection for rectal cancer in Uganda.
Specific objectives
1. To determine the quality of life of patients who have had surgical resection for rectal cancer in Mulago Hospital.
2. To assess the factors associated with a poor quality of life following surgical resection for rectal cancer in Mulago Hospital.

 Uganda 2026-06-01 18:15:40 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Mugonya
ID: UNCST-2025-R018082
 DETERMINANTS OF PARTICIPATION OF SMALLHOLDER COFFEE FARMERS IN THE AGROFORESTRY CARBON REMOVAL BUSINESS
REFNo: A753ES

- To examine the factors that influence the participation of smallholder coffee agroforestry farmers in the Voluntary Carbon Market (VCM) -To characterise business models for agroforestry carbon projects across a context and mechanisms continuum - To assess the perceptions of smallholder coffee-agroforestry farmers of benefits and constraints associated with participating in carbon projects - To examine the implementation mechanisms of carbon projects within smallholder coffee agroforestry sector in Uganda - To establish a multi-stakeholder co-design process for prototyping inclusive business models for agroforestry ecosystem services among smallholder coffee farmers in Uganda
 Uganda 2026-06-01 18:13:55 2029-06-01 Agricultural Sciences Non-Clinical Trial Degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Mobile Phone Surveys for NCD Risk Factor Estimation in Uganda
REFNo: HS7319ES

Objective 1: Compare IVR and computer assisted telephone interviews (CATI) performances.
Objective 2: Optimize urban/rural questions to better triangulate residences in urban and rural areas.
Objective 3: Better understand interactive voice response (IVR) disposition codes generated by IVR platforms and services to improve response rate.
 Uganda 2026-06-01 18:12:47 2029-06-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FELIX YETUNGYE KAMUHANDA
ID: UNCST-2026-R023493
 Enhancing childhood cancer outcomes in southwestern Uganda: Addressing diagnostic and treatment delays, and describing a patient cohort at the Mbarara Regional Referral Hospital
REFNo: HS7579ES

The overarching objective is to improve timely diagnosis and treatment, and outcomes for childhood cancer patients in southwestern Uganda by characterizing childhood cancer patients seen at the Paediatric Cancer unit (PCU) in MRRH, assessing the diagnostic pathways and delays, capturing experiences of caretakers and key stakeholders, and developing a context-specific referral algorithm supported by quality paediatric cancer data. The specific objectives include: 1. To characterize the cohort of childhood cancer patients presenting to the PCU (including sociodemographic, symptom progression, clinical presentation at PCU, cancer types, diagnostics, treatments, and outcomes) using a validated database. 2. To describe the patient journey and delays at each stage of the three delays model (detailed in the figure 1) with a focus on: a. Quantifying the average time intervals (delays) from symptom onset to confirmed diagnosis and treatment initiation of common childhood cancers, and to describe the implications of these delays on the outcomes of the patient cohort. b. Describing the healthcare pathways and determining factors associated with duration of delays for common childhood cancers. c. Exploring the lived experiences of caretakers of children diagnosed with cancer, from initial symptom recognition to diagnosis and treatment initiation. d. Exploring the perceptions of key stakeholders (including healthcare providers at all levels of the healthcare system and key community informants) on childhood cancer and on its diagnosis and treatment initiation delays. 3. To collaboratively develop and refine context-specific referral decision algorithms for childhood cancers to improve early identification and referral efficiency.
Uganda 2026-06-01 18:09:54 2029-06-01 Medical and Health Sciences Non-degree Award
Simon  ACHUU Peter
ID: UNCST-2025-R017228
 Impact of Climate Variability on Rangelands Ecosystems Productivity and Mitigation Measures in Awoja Catchment Area, Eastern Uganda
REFNo: NS1255ES

1. To analyze the relationship between climate variability and rangeland ecosystem productivity patterns in the Awoja catchment area between 1984 and 2024.
2. To examine community perceptions on the impacts of climate variability on rangelands ecosystem productivity in the Awoja catchment area.
3. To examine the effectiveness of existing community based copying strategies to mitigate negative impacts of climate variability on rangeland ecosystem productivity in Awoja catchment area.
4. To design and test selected ecosystem based adaptation-EbA techniques in maintaining rangeland ecosystem productivity under climate variability scenario in Awoja catchment area.

 Uganda 2026-06-01 18:08:07 2029-06-01 Natural Sciences Non-Clinical Trial Degree Award
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