Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JESSE LIMO MWANGA
ID: UNCST-2025-R019331
 Development of a web-based project management application to enhance construction project performance
REFNo: SS4618ES

I. To determine the gaps in existing project management applications based on stakeholder requirements. II. To design a prototype web-based project management application that addresses the gaps in existing applications based on stakeholder requirements. III. To assess the effectiveness of the prototype web-based project management application in addressing the gaps in existing applications and enhancing construction project performance in Uganda.
Uganda 2025-12-05 19:08:11 2028-12-05 Social Science and Humanities Non-Clinical Trial Degree Award
Rebecca Nuwematsiko
ID: UNCST-2022-R010501
 Prescribing and dispensing practices of antimicrobials and drivers for inappropriate use among staff in licensed private retail pharmacies in Kampala and Mbarara cities, Uganda
REFNo: HS6581ES

o explore drivers of inappropriate use of antimicrobials in licensed private retail community pharmacies in Kampala and Mbarara cities,To assess antimicrobial prescribing and dispensing practices among staff in licensed private retail community pharmacies in Kampala and Mbarara cities.,To determine the level of knowledge and perceptions on antimicrobial resistance among staff in licensed private retail community pharmacies in Kampala and Mbarara cities.,To assess antimicrobial prescribing and dispensing practices and drivers of inappropriate use among staff in selected licensed private retail community pharmacies in Kampala and Mbarara cities in Uganda so as to add on the available evidence for fostering antibiotic stewardship in private pharmacies.,
 Uganda 2025-12-05 18:44:34 2028-12-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emma Wamono
ID: UNCST-2025-R017178
 Impact of anthropogenic stressors on ecosystem health and potential in-stream restoration measures of river Manafwa catchment in eastern Uganda
REFNo: NS993ES

I.Examine the influence of anthropogenic stressors on Physico-chemical water quality parameters in river Manafwa catchment in eastern Uganda. II.Analyse the influence of anthropogenic stressors on the macroinvertebrate assemblages in river Manafwa catchment in eastern Uganda. III.Asses the community perception on how their activities affect aquatic ecosystem health in river Manafwa catchment in eastern Uganda. IV.Establish and asses the performance of selected restoration measures in enhancing river ecosystem health in river Manafwa catchment in eastern Uganda.
Uganda 2025-12-05 18:39:17 2028-12-05 Natural Sciences Non-Clinical Trial Degree Award
Emmanuel  Luyirika BK
ID: UNCST-2025-R021521
 Destigmatizing Breast Cancer: Village Health Teams Using a Video Education Tool
REFNo: SS4394ES

1)Improve knowledge about breast cancer among VHTs 2)Evaluate if community members found this video tool to be an acceptable and helpful way to learn more about breast cancer. 3)Evaluate if VHTs found this video tool to be an acceptable and helpful way to share information about breast cancer.
Uganda 2025-12-05 18:37:27 2028-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening (SIMCS)- A Cluster Randomized Trial
REFNo: HS6567ES

(ii) To evaluate the impact of the SCD SIMCS on access to screening and care and outcomes of children with SCD,
 Uganda 2025-12-05 18:30:02 2028-12-05 Medical and Health Sciences Clinical Trial Non-degree Award
Julius Ssendiwala
ID:
EVALUATION OF HIV INTEGRATION INTO ROUTINE CARE AT HEALTH FACILITIES IN UGANDA: LESSONS LEARNT FROM -THE COVID-19 HIV SERVICE DELIVERY ADAPTATIONS AND THE US PRESIDENT EXECUTIVE ORDERS
REFNo: HS6720ES

1. To document the health system adaptations that occurred during the COVID-19 pandemic, and the recent US President Executive Orders and how are they are being utilized for current HIV integration efforts?
2. To document the various models of HIV integration currently being implemented, and the factors that facilitate or hinder their successful implementation
3. To assess the uptake, feasibility, and acceptability of integrating HIV services into routine healthcare services

 Uganda 2025-12-03 18:46:20 2028-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 VALIDATION OF AN OFFLINE DEEP – LEARNING AI MODEL FOR ESTIMATING FVC AND FEV₁ FROM CHEST X‑RAYS IN A RESOURCE‑LIMITED UGANDAN CLINICAL SETTING.
REFNo: HS6703ES

Primary Objective
To evaluate the accuracy of an offline, deep-learning AI model in estimating forced vital capacity (FVC) and forced expiratory volume in one second (FEV₁) by comparing AI-predicted values against spirometry-measured values.

Secondary Objective
To determine the agreement between AI-derived and spirometry-derived FEV₁/FVC ratios, and assess its utility for identifying airflow obstruction (i.e., FEV₁/FVC < 0.70).
 Uganda 2025-12-01 22:01:17 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
 Exploring Factors Influencing COVID-19 Vaccination Uptake: A Qualitative Study in Uganda
REFNo: SS4582ES

To explore the factors and contextual differences that influenced COVID-19 vaccination uptake in Uganda, to compare these with experiences in Burundi and Rwanda, and to identify key predictors and opportunities for regional learning
 Kenya 2025-12-01 21:44:17 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
STELLA NABIRYE
ID: UNCST-2024-R003637
 Evaluation of outcomes of anticoagulation and factors associated with Time in Therapeutic Range among Rheumatic heart disease patients on vitamin K antagonists attending care at the Uganda Heart institute
REFNo: HS6728ES

General objective
To evaluate the outcomes of anticoagulation and factors associated with time in therapeutic range among Rheumatic heart disease patients on vitamin K antagonist attending care at Uganda Heart Institute

specific objectives
1.To determine the clinical outcomes of anticoagulation among Rheumatic heart disease patients on vitamin K antagonists attending care at Uganda Heart Institute

2.To determine the factors associated with time in therapeutic range among Rheumatic disease patients on vitamin K antagonists attending care at Uganda Heart Institute

3.To explore patients’ attitudes and knowledge on the use of vitamin K antagonists among Rheumatic heart disease patients attending care at Uganda Heart Institute

4.To explore clinicians’ perception of the use of vitamin K antagonists in managing patients with Rheumatic heart disease attending care at Uganda Heart Institute
 Uganda 2025-12-01 21:35:22 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
ATUHAIRE JUSTUS
ID: UNCST-2024-R004914
 Improving the quality of face sheet completion at Mulago National Referral Hospital
REFNo: HS6627ES

1. To determine the proportion of face sheet that are not complete at Mulago National Referral Hospital. 2. To identify the factors that contribute to failure of doctors to complete face sheet at Mulago National Referral Hospital. 3. To identify the measures that can be put forward towards completion of face sheet at Mulago National Referral Hospital.
Uganda 2025-12-01 21:28:40 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mirembe SarahAngella
ID: UNCST-2025-R021000
 Influence of Women's Participation In The Rice Value Chain on Household Dietary Diversity in Eastern Uganda
REFNo: SS4586ES

1. To examine the extent of women’s participation in the rice production, processing, and marketing activities within selected rice-oriented households in Namasagali sub-county, Eastern Uganda. 2. To identify the institutional factors that influence women’s participation as rice value chain actors at the household level. 3. To assess the dietary diversity of rice-oriented households in Namasagali sub-county, Eastern Uganda. 4. To establish a relationship between women’s participation and household dietary diversity.
 Uganda 2025-12-01 21:16:33 2028-12-01 Social Science and Humanities Degree Award
Nambusi Kyegombe Davina Ndibalekera
ID: UNCST-2022-R009559
 Ethics in Action in Low and Middle-Income Settings (EALMIC) Study: Challenges faced by researchers in applying ethical principles in Uganda
REFNo: SS4624ES

This aim of this study is to explore the emotional and psychological challenges faced by health researchers in Uganda working with vulnerable populations and on sensitive topics, in order to inform ethical guidelines and support strategies for enhancing researchers' well-being.
The study will be guided by five main objectives:
1. To explore researchers’ experiences of conducting research with vulnerable populations and on sensitive topics.
2. To explore how researchers’ experiences affect their wellbeing.
3. To identify coping and support mechanisms used by researchers to respond to their experiences.
4. To assess the ethical challenges faced when working with vulnerable populations.
5. To explore researchers’ perceptions of the role of cultural factors, including ubuntu principles, patriarchal gender norms, respect for elders and social hierarchies, on researchers’ experiences.

 Uganda 2025-12-01 21:13:31 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Atwebembeire John Mushomi
ID: UNCST-2025-R022006
 Evaluation of the ASRH Gatherings for Young Mother Gardeners Program
REFNo: SS4584ES

To assess the short- and medium-term impacts of the ASRH Gatherings and integrated livelihood support on young mothers in Kasese District.1. i. Examine how the program addresses challenges faced by adolescent mothers. 2. ii. Document transformative changes in participants’ lives, including aspirations, health, and livelihoods. 3. iii. Provide evidence-based recommendations for strengthening and scaling the program.
 Uganda 2025-12-01 21:05:46 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Doreen Nakagaayi
ID: UNCST-2023-R006587
 Rheumatic Heart Disease among Pregnant women in Northern Uganda: Prevalence, Impact on Pregnancy Outcomes and Strategy for Early Identification.
REFNo: HS6717ES

General Objectives
To determine the prevalence of RHD in pregnancy in Northern Uganda, the maternal and fetal outcomes and use this data to develop and validate clinical risk scores that predict presence of RHD in pregnancy and those at increased risk for adverse maternal outcomes.
Specific Objectives
Objective 1
A. To determine the prevalence of RHD among pregnant women in a community setting in Northern Uganda.
B. To design a diagnostic risk score that predicts presence of RHD in early pregnancy in Northern Uganda
Objective 2
A. To determine the maternal, and fetal outcomes of pregnant women with RHD in a community setting in Northern Uganda.

Uganda 2025-12-01 20:59:51 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Cromwell Okello
ID: UNCST-2025-R021939
 Rethinking the Potential of Formal Education in Buttressing the Peace–Economic Development Nexus among Karamojong Pastoralists in Moroto District, Uganda.
REFNo: SS4615ES

The study aims to critically examine the interconnections between formal education, peacebuilding, and economic development among the Karamojong pastoralist communities in Moroto District, Northeastern Uganda. Specifically, it seeks to understand how formal education can be strategically leveraged to promote social cohesion, gender equity, and sustainable livelihoods, while interrogating the socio-cultural, political, and economic dynamics that influence its implementation and outcomes.
Anchored in Pierre Bourdieu’s Theory of Practice, the study explores how education operates as both a field of social reproduction and a potential catalyst for transformation within a historically marginalised pastoralist society.
Research Objectives:
To realise the overarching aims of the study, the following research objectives have been framed:
1. To explore how Karamojong pastoralists experience and perceive access to formal education across different levels (primary, secondary, tertiary, and vocational), focusing on the social, cultural, economic, and geographical factors that shape participation and exclusion.
2. To examine the extent to which formal education, in its current form and cultural relevance, contributes to conflict mitigation, peacebuilding, social cohesion, and economic resilience among Karamojong pastoralists.
3. To analyse how the socio-cultural, political, and economic characteristics of the Karamojong people influence the formulation and implementation of educational policies and strategies within their region.
4. To investigate how formal education shapes gender relations, power dynamics, and opportunities for both women and men in the Karamojong community, particularly in relation to peacebuilding and economic development.
5. To co-develop culturally relevant educational strategies and curriculum innovations that integrate indigenous knowledge and support peacebuilding, gender equity, and sustainable development in pastoralist contexts.
6. To formulate evidence-based policy recommendations that align educational policies and practices with the socio-cultural realities, aspirations, and economic needs of the Karamojong pastoralist communities.
 Uganda 2025-12-01 20:53:21 2028-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Assessing Willingness to Pay (WTP) for Family Planning Products in Uganda: Insights into consumer demand and affordability
REFNo: HS6749ES

Study Aim:
The overall aim of this study is to assess and understand the factors influencing willingness to pay for the different FP products in the Ugandan Market and barriers to WTP for the contraceptive’s products from all key stakeholders in the current market. Development of the study aims was guided by a series of consultative meetings with key stakeholders including program implementers and review of the recent literature on WTP studies. The study generates evidence to fill key gaps identified from the previous studies conducted on WTP focusing on the underlying factors to client WTP for FP products and services.
1.4 Specific Objectives:
1. To assess the current willingness to pay for Family Planning products among different population segments in Uganda.
2. To identify socio economic and demographic factors influencing willingness to pay for contraceptives
3. To integrate findings from previous WTP studies to provide a comprehensive -analysis and holistic understanding of pricing dynamics.
4. To identify key factors influencing pricing decisions, including cost-to-delivery and market affordability.

 Uganda 2025-12-01 20:44:08 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Akampurira
ID: UNCST-2025-R019367
 Stakeholder Engagement, Entrepreneurship Education, and Entrepreneurial Intention among Business Graduates of Chartered Universities in Southwestern Uganda
REFNo: SS4425ES

1. To determine the relationship between stakeholder engagement and entrepreneurial intention among university business graduates. 2. To assess the relationship between stakeholder engagement and entrepreneurship education among university business graduates. 3. To evaluate the relationship between entrepreneurship education and the entrepreneurial intention of university business graduates. 4. To analyse the mediating role of entrepreneurship education on the relationship between stakeholder engagement and entrepreneurial intention among university business graduates.
Uganda 2025-12-01 20:37:44 2028-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Assessment of Nasal Microbiome, Inflammatory Markers, and Infectious Agents among individuals with Biomass Fuel COPD in Uganda ACRONYM: ASCENT–NASAL Study
REFNo: HS6748ES

Aim 1: Characterize the nasal microbiome composition among individuals with and without COPD who
have different levels of air pollution exposure.

Aim 2: Assess nasal inflammatory marker differences among individuals with and without COPD who
are exposed to different levels of air pollution.

Aim 3: Determine the prevalence of viral and bacterial respiratory pathogens among individuals with
and without COPD and their association with PM2.5 exposure.
 Uganda 2025-12-01 14:33:20 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Safety, preliminary efficacy, and Pharmacokinetics of Herbal/Natural/ Traditional therapeutic products for the management of Diabetes Mellitus in Uganda.
REFNo: HS6530ES

Main Objective
1. To evaluate the safety, effectiveness and pharmacokinetics of 3 selected NDA- notified herbal/natural/traditional therapeutic products in Uganda, designated IMP1, IMP2, and IMP3.
2. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of natural therapeutics in Uganda.

Specific Objectives
1. To determine the efficacy of selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the treatment of diabetes mellitus in adult patients in Uganda
2. 2. To assess the effect of the selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) on specific cardio-metabolic characteristics of adult patients with DM in Uganda.
3. To assess clinical and laboratory adverse events associated with selected NDA- notified herbal/natural/traditional therapeutic products, specifically IMP1, IMP2 and IMP3 in adult patients with DM in Uganda.
4. To investigate the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.
5. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of herbal/natural/traditional therapeutics in Uganda.e the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.

Uganda 2025-12-01 14:19:22 2028-12-01 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Matovu Wasswa
ID: UNCST-2025-R021145
 Understanding Power, Institutions, and Policy Dynamics: A Political Economy Analysis of Youth Employment in Uganda
REFNo: SS4607ES

Research Questions The political economy analysis aims to answer two overarching research questions: I. How can current policies and regulatory frameworks be activated and enhanced to provide dignified and fulfilling work opportunities for youth in Uganda? II. What industrial and trade policies and/or plans will enable Uganda to leverage its demographic transition, the 4th industrial revolution, and the evolving digital economy to create adequate opportunities for dignified and fulfilling work for Ugandan youth? Purpose and Objectives The main purpose of this study is to examine how political, institutional, and economic structures interact to shape youth employment outcomes in Uganda. Specifically, the research seeks to: • Map the formal and informal policy, regulatory, and institutional frameworks governing youth employment. • Analyse the interests, incentives, and power dynamics of key actors who influence or obstruct youth employment reforms. • Understand the lived experiences, perceptions, and aspirations of young people in relation to work, inclusion, and voice. • Identify enablers and constraints to the implementation of effective and inclusive employment strategies. • Generate context-sensitive, actionable recommendations for policy and institutional reform.
Uganda 2025-11-26 14:32:03 2028-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
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