Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Richard Selwanga
ID: UNCST-2025-R018576
 THE EVOLUTION OF THE LINGUISTIC LANDSCAPE OF KAMPALA: LANGUAGE POLICY, MULTILINGUALISM, AND PUBLIC PERCEPTIONS
REFNo: SS4333ES

(i) To examine the language of public signs in the LL Kampala District from the colonial to post-colonial period. (ii) To analyse the impact of language policies on language visibility in the LL of Kampala District from the colonial to post-colonial period. (iii) To investigate the role that multilingualism has played in shaping the LL of Kampala District from the colonial to post-colonial period. (iv) To explore the perceptions of the target readership towards language use in the contemporary LL of Kampala District.
 Uganda 2025-10-08 13:06:29 2028-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
Mulebeke Ronald
ID: UNCST-2025-R017304
 IMPLEMENTATION AND ASSESSMENT OF THE THRIVE PROJECT; STRENGTHENING MENTAL HEALTH AND SOCIOECONOMIC RESILIENCE AMONG YOUTH LIVING WITH HIV IN WAKISO DISTRICT, UGANDA
REFNo: HS6493ES

1. To conduct a gap assessment of the current mental health services for youth living with HIV in Wakiso District.

2. To explore the structural, social and policy related barriers to effective integration of mental health services into HIV care for YLWH in Wakiso District.

3. To explore the structural, social and policy related facilitators to effective integration of mental health services into HIV care for YLWH in Wakiso District.
4. To assess the feasibility of integrating Group Support Psychotherapy training in improving mental health outcomes among YLWH at Mildmay Uganda Hospital in Wakiso District.
5. To assess the feasibility of economic empowerment in improving mental health outcomes among YLWH seeking care at Mildmay Uganda Hospital in Wakiso District.
6. To conduct a process evaluation of the THRIVE project among YLWH at Mildmay Uganda Hospital in Wakiso District.

Uganda 2025-10-08 11:21:31 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert MPIIRA
ID: UNCST-2022-R005391
 Community Engagement and Access to Services Related to Gender-Based Violence and Sexual Reproductive Health and Rights in Uganda: A Qualitative Study
REFNo: SS4367ES

● Do male influencers view themselves as agents of change (or potential agents of chance) for AGYW? Can they be adequately motivated to serve as champions or advocates for AGYW rights, and if so, what would incentivize them to play that role most effectively?,● What role do YDCs or other community-based support groups/networks play in supporting AGYW\'s social and economic empowerment, as well as the long-term sustainability of interventions?,● What are the current service gaps in SRHR and GBV within the targeted communities? What institutional or system-strengthening support is needed to address these gaps and improve the effectiveness of referrals?,● What are the main barriers associated with discussing SRHR and GBV topics with family members and men toward shifting social norms and what strategies can help effectively mitigate these barriers?,● What are the key barriers and enablers faced by the AIM 2.0 programme in influencing existing community structures, particularly informal structures, to improve the socio-economic conditions and empowerment for AGYWs?,To ensure the implementers fully understand the contexts where they are working and if necessary adapt the implementation activities through more enhanced community engagement in order to improve access to services for AGYW, particularly SRHR and GBV protection. ,
 Uganda 2025-10-07 10:35:55 2028-10-07 Social Science and Humanities Non-degree Award
Musa Sekikubo
ID: UNCST-2021-R014010
 Congenital and Maternal Point of care Rapid Testing for Syphilis Study, Uganda (COMPARTS)
REFNo: HS6397ES

Main Objective: Conduct a pilot study of the reformulated Dual Path Platform (DPP) Syphilis Test and Treat (TnT) and Congenital Syphilis (CS) test, manufactured by Chembio, for a cohort of mother-baby pairs from Uganda.


Specific Objectives
a) Assess treponemal and non-treponemal antibody levels in perinatal blood from mothers and compare these findings with IgM and IgG results from the DPP Syphilis TnT assay.

b) Assess treponemal and non-treponemal antibody levels in newborn and cord blood from paired babies and compare these findings with IgM and IgA results from the DPP Syphilis CS assay.

c) Determine the performance characteristics of the POC device by calculating the sensitivity, specificity, positive and negative predictive values, and the proportion of tests that return invalid results or errors.
 Uganda 2025-10-07 10:25:59 2028-10-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patience Atukunda
ID: UNCST-2023-R005832
 BUILDING ARTIFICIAL INTELLIGENCE MODELS FOR BREAST CANCER DIAGNOSIS USING CLINICAL, ULTRASOUND AND CYTOLOGY DATA
REFNo: SIR559ES

i To build and evaluate an Artificial Intelligence Model for prediction of breast cancer using clinical features ii To build and evaluate an Artificial Intelligence model for breast cancer diagnosis using ultrasound data iii To build and evaluate an Artificial Intelligence model for breast cancer diagnosis using cytology data iv To build and evaluate an Artificial Intelligence model to integrate clinical, radiology and pathology findings into one report
Uganda 2025-10-01 12:21:26 2028-10-01 Engineering and Technology Non-Clinical Trial Degree Award
Anne Akello Ruth
ID: UNCST-2022-R009131
 ASSESSMENT OF OCCUPATIONAL HAZARDS AND HEALTH EFFECTS AMONG WORKERS OF GRAIN MILLS IN SOROTI CITY, UGANDA
REFNo: HS6278ES

1. To identify occupational hazards in work places within grain mills in Soroti city.
2. To establish knowledge, attitudes and practices (KAP)on occupational hazards among workers of grain mills in Soroti city.
3. To examine the status of implementation of OSH policies by owners and workers of the grain mills in Soroti city.
4. To determine the health effects of exposure to occupational hazards among workers of grain mills in Soroti city
5. To establish the factors that influence occurrence of occupational hazards and health effects among workers of grain mills in Soroti city.

 Uganda 2025-10-01 12:20:18 2028-10-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Marvious Kiwanuka
ID: UNCST-2023-R006348
 Surveillance of human and vector behaviors to understand malaria transmission at sentinel sites in Uganda
REFNo: HS6483ES

To monitor geographic and temporal trends in malaria burden and assess the impact of population level control interventions across a range of epidemiological settings in Uganda in relation to human behaviors and vector bionomics.
 Uganda 2025-09-30 14:43:46 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Judith Nanyondo Semanda
ID: UNCST-2025-R019750
 Design and Evaluation of Human-Centred, Data-Driven Bundles for Improving Hand and Surface Hygiene Practices in Ugandan Health Facilities
REFNo: HS6507ES

1. To explore the barriers and facilitators to hand and surface hygiene compliance among clinical staff and cleaners in the health facilities of Masaka region.
2. To design data-driven hand and surface hygiene care bundles using a human centered design approach.
3. To assess the effectiveness of hand and surface hygiene care bundles in improving compliance with hand and surface hygiene practices among clinical staff and cleaners.

 Uganda 2025-09-30 14:41:24 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JAMES KAWUKI STEPHEN
ID: UNCST-2025-R019616
 ENERGY POVERTY, HOUSEHOLD HEALTH STATUS AND HEALTH EXPENDITURE: A STRATEGIC MANAGEMENT AND POLICY IMPLICATION IN UGANDA’S ENERGY AND HEALTH SECTORS
REFNo: SS4396ES

i. To examine the relationship between energy poverty and Household health expenditure. ii. To evaluate the relationship between energy poverty and Household health status, with specific attention the role of gender and energy usage behaviour. iii. To establish the relationship between Household health expenditure and Household health status. iv. To develop a strategic management model that incorporates affordability sensitivity and gender- responsive interventions to mitigate energy poverty and improve health outcomes.
Uganda 2025-09-30 14:40:12 2028-09-30 Social Science and Humanities Non-Clinical Trial Degree Award
Apolo Balyegisawa P
ID: UNCST-2025-R017645
 Evaluation of the XF 300 Flow Cytometer, CD4 easy count kit, CD4% easy count kit and CD4/CD8 easy count kit in Tests 1112 - Explorative External Method Comparison Study and 1149.2 - Clinical Performance Study
REFNo: HS6435ES

Test 1112 - Compare the results from the XF-300 Flow Cytometer and its reagent kits with the comparator device (FACSLyric) and reagent kits Test 1149.2 - Investigate the clinical performance of the XF-300 Flow Cytometer in combination with the three kits CD4, CD4% and CD4/CD8 easy count kit.
Uganda 2025-09-30 14:39:06 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daisy Aliwaru
ID: UNCST-2025-R018043
 University Management And Pedagogical Innovations In Education: A Comparative Study Of Public And Private Universities In Uganda
REFNo: SS4340ES

1. To analyse the university management structures and practices that support pedagogical innovations in education at Muni University and Uganda Christian University. 2. To examine the effect of resource allocation for pedagogical innovations in education at Muni University and Uganda Christian University. 3. To determine the effect of incentives on pedagogical innovations in education at Muni University and Uganda Christian University. 4. To examine the effect of academic freedom for pedagogical innovations in education at Muni University and Uganda Christian University.
Uganda 2025-09-30 14:36:34 2028-09-30 Social Science and Humanities Non-Clinical Trial Degree Award
Emmanuel  Arinaitwe
ID: UNCST-2021-R011754
 THE SPREAD OF ARTEMISININ RESISTANCE IN AFRICA(SPARTAN 3); A longitudinal study to determine the fitness of artemisinin resistant parasites among asymptomatic infections
REFNo: HS6215ES

To detect a difference in the duration of ΔPfK13 versus wildtype infections. In addition to infection duration and parasite half-life as main outcomes of interest, we will compare ΔPfK13 and wildtype infections in terms of: - gametocyte commitment and gametocyte production - gametocyte half-life,
 Uganda 2025-09-30 14:35:17 2028-09-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Helen Byakwaga
ID: UNCST-2019-R001168
 A Phase III/IV factorial randomised double-blind trial to compare the addition of dapagliflozin versus placebo, and rosuvastatin/ezetimibe versus pitavastatin, in patients with HIV on integrase strand transfer inhibitor-based antiretroviral therapy with elevated metabolic risk (Optimising metabolic management on integrase-based antiretroviral therapy – the OPTIMAR Study)
REFNo: HS5819ES

To assess the impact of pitavastatin vs. rosuvastatin/ezetimibe from baseline to 48 weeks on: fasting lipids, cardiovascular disease risk assessment measures; inflammatory biomarkers; and safety and tolerability,To assess the impact of dapagliflozin vs. placebo from baseline to 48 weeks on: intermediate markers of cardiovascular disease risk; cardiovascular disease risk assessment measures; clinical consequences of increased body weight; and safety and tolerability of dapagliflozin,To assess the impact of pitavastatin vs. rosuvastatin/ezetimibe on LDL concentration change from baseline to week 24,To assess the impact of dapagliflozin vs. placebo on absolute weight change from baseline to week 24,The overall objective of the study is to examine the impact of dapagliflozin vs. placebo on metabolic parameters in PWH with high metabolic risk who are on INSTI-based ART.,
 Uganda 2025-09-30 14:11:23 2028-09-30 Medical and Health Sciences Clinical Trial Non-degree Award
Melody Niwamanya
ID: UNCST-2019-R000928
 Gender Equality and Empowerment of Women and Girls (GEEWG) Measurement Toolkit Pilot in Uganda
REFNo: SS4458ES

5. Produce a refined set of tools and practical implementation guidance to inform subsequent pilots and eventual scale-up.,4. Verify that safeguarding, consent/assent, referral pathways, and data protection procedures function effectively and safely in this setting.,3. Assess data quality and preliminary measurement performance of the toolkit to identify items and scales that need refinement for clarity and consistency.,2. Establish cultural and linguistic appropriateness of items across respondent groups and identify questions that require revision based on respondent understanding and contextual fit.,1. Determine feasibility and acceptability of administering the GEEWG toolkit to learners, caregivers, teachers, school committee members, and community leaders in Kyangwali (including length, language, flow, and field logistics).,To pilot and validate a flexible, context-sensitive Gender Equality and Empowerment of Women and Girls (GEEWG) Measurement Toolkit within Kyangwali Refugee Settlement to assess its relevance, accuracy, and usability for capturing gender-transformative outcomes in MYRP-supported education interventions.,
 2025-09-29 16:30:10 2028-09-29 Social Science and Humanities Non-degree Award
Prudence Beinamaryo
ID: UNCST-2023-R007239
 The feasibility, acceptability and health impact assessment of the co-administration of ivermectin and albendazole vs albendazole alone, in the frame of mass drug administration to school-aged children in Uganda: A large-scale distribution
REFNo: HS6511ES

To assess the health impact of both treatment schemes and compare prevalence reduction of soil-transmitted helminth infections at school level by treatment arm ,To document safety of routine ivermectin-albendazole administration,To document the performance (i.e., coverage and reach) of the two treatment arms,To collect data on implementation-related costs and assess the additional resource needs and costs for the co-administration of ivermectin and albendazole compared to albendazole alone ,To evaluate the acceptability of sensitization and distribution strategies informed by the pilot study of co-administered ivermectin and albendazole among receiving communities,To assess the feasibility (including aspects of training, materials and processes) of the co-administration of ivermectin and albendazole compared to albendazole alone at large-scale in the frame of school-based MDA in Uganda,To assess the feasibility and acceptability of the co-administration of ivermectin and albendazole compared to albendazole alone during school-based MDA in Uganda.,
 Uganda 2025-09-29 16:25:20 2028-09-29 Medical and Health Sciences Non-degree Award
MARIA NAMULWANA LOUISE
ID: UNCST-2025-R019516
 Evaluating the durability of the immune response to fractional and full dose Yellow Fever vaccination (YEFE/NIFTY Extension Study )
REFNo: HS6461ES

• To describe the current age-stratified seropositivity rates in YEFE and NIFTY participants at 2-8 years after initial vaccination by vaccine dose received, and to compare seropositivity rates across trials and groups including shared data from the MRCG trial.
Uganda 2025-09-26 18:39:14 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Orodriyo
ID: UNCST-2024-R002224
 PROCUREMENT MONITROING PRACTICES AND ROAD TRANSPORT SERVICE DELIVERY IN LOCAL GOVERNMENTS IN UGANDA: A CASE STUDY OF ROAD CONSTRUCTION IN ARUA CITY.
REFNo: SS4296ES

1. To assess the impact of performance score cards on road transport service delivery in Arua city.
2. To evaluate the contribution of supervision reports towards road transport service delivery in Arua city.
3. To assess the effectiveness of capacity building on road transport service delivery in Arua city.
4. To examine the moderating effect of procurement monitoring practices on road transport service delivery in Arua city.
 Uganda 2025-09-26 18:35:57 2028-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Tadeo   Nsubuga
ID: UNCST-2023-R007982
 Factors associated with non-uptake and perceptions about TB preventive therapy among household contacts of TB patients in Moroto district, Uganda.
REFNo: SS4269ES

2. To understand individual and community perceptions about TPT among household contacts of bacteriologically confirmed TB patients ,1. To determine the factors associated with non-uptake of TB preventive therapy among household contacts of bacteriologically confirmed TB patients ,The overall objective is to determine the factors associated with non-uptake and perceptions about TPT among household contacts of bacteriologically confirmed TB patients in Moroto district, Karamoja sub-region, Uganda. ,
 Uganda 2025-09-26 18:34:54 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eleanor Matthews
ID: UNCST-2024-R003472
 Assessing development of reciprocity among juvenile chimpanzees (Pan troglodytes schweinfurthii)
REFNo: NS1024ES

This project assesses the extent to which juvenile chimpanzees use strategies of imitation and observation to learn to reciprocate cooperative behaviors common among adults i.e. grooming and coalitionary action. This project also aims to assess the extent to which cooperative tendency is observable during the juvenile life history phase, and to what extent juvenile cooperative behaviors may predict adult behavioral phenotypes.
USA 2025-09-26 18:30:33 2028-09-26 Natural Sciences Non-Clinical Trial Degree Award
ATWIINE CHRISS
ID: UNCST-2025-R018550
 ASSESSMENT OF RISK FOR INDUSTRIAL SORTING MACHINE FAILURES CAUSED BY VOLTAGE FLUCTUATIONS AND STRATEGIES TO IMPROVE POWER QUALITY MANAGEMENT
REFNo: SIR551ES

iTo identify the primary causes of voltage fluctuations affecting industrial sorting machines at ACPCU Ltd in Sheema District by analyzing power supply logs and equipment response data collected over a three-month period August–October 2025. ii. To assess the impact of voltage fluctuations on the operational performance of industrial sorting machines by conducting real-time performance monitoring and error tracking from August to October 2025. iii. To evaluate the risk levels associated with voltage fluctuations using Probabilistic Risk Assessment (PRA), and to simulate potential failure outcomes using MATLAB and Monte Carlo analysis, in order to recommend mitigation strategies by November 2025.
 Uganda 2025-09-26 18:29:20 2028-09-26 Engineering and Technology Non-Clinical Trial Degree Award
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