Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sean OHara
ID: UNCST-2025-R022486
Budongo Forest Tortoise Project
REFNo: NS1067ES

Main:
To collect baseline data on the forest tortoise in the Budongo Forest Reserve.

Specific:
1. To quantify tortoise density, abundance and occupancy.
2. To begin to quantify tortoise spatial ecology and behaviour.
3. To ascertain public perception of forest tortoises and better understand any anthropogenic threats to their conservation
UK 2026-08-11 20:29:57 2029-08-11 Natural Sciences Non-Clinical Trial Non-degree Award
Allon Bomujuni
ID: UNCST-2026-R025675
Organizational Support and Performance of Youth Beekeepers: A Case of TUNADO, Kamwenge District, Uganda
REFNo: SS5574ES

I. To examine the influence of capacity building support on the performance of youth beekeepers supported by TUNADO in Kamwenge district. II. To assess the influence of input support on the performance of youth beekeepers supported by TUNADO in Kamwenge district. III. To determine the influence of market access support on the performance of youth beekeepers supported by TUNADO in Kamwenge district.
Uganda 2026-08-11 20:28:17 2029-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
LYDIA  MULWANYI MUKOMBE
ID: UNCST-2026-R024050
NAVIGATING THE WATERS: IMPACT OF CLIMATE-INDUCED FLOODING ON MATERNAL AND NEONATAL HEALTH - A MIXED METHODS STUDY OF BWAISE, KAMPALA CITY
REFNo: SS5532ES

General Objective To evaluate the impact of climate-induced flooding on maternal and neonatal health outcomes in Bwaise, Kampala, by integrating satellite-derived spatial climate data and DHIS2 administrative records through a community-anchored, mixed-methods approach. Specific Objectives 1) Qualitative Exploration & Participatory Mapping: To document community-lived experiences, localized environmental vulnerabilities, physical bottlenecks, and local enablers influencing maternal and neonatal healthcare access in Bwaise. 2) Quantitative Epidemiological Modeling: To quantify the direct and structural relationships between satellite-derived flooding events and individual maternal and neonatal health outcomes. 3) Participatory Co-Design & Policy Translation: To collaboratively co-design localized, climate-resilient maternal safety nets with Bwaise residents and identify strategic structural entry points for Kampala Capital City Authority (KCCA) and Ministry of Health (MoH) policy translation.
Uganda 2026-08-11 20:24:50 2029-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Diana Asiimwe Ritah
ID: UNCST-2025-R019047
EVALUATION OF SAFE STRATEGY IMPLEMENTATION IN TRACHOMA-ENDEMIC KARAMOJA REGION: A CASE STUDY OF PROGRESS AND GAPS
REFNo: HS8380ES

General Objective To evaluate the implementation of the SAFE strategy for trachoma elimination in Moroto, Napak and Nabilatuk districts of the Karamoja region, Uganda. Specific Objectives 1. To assess the level of implementation of the SAFE strategy components (Surgery, Antibiotics, Facial cleanliness, and Environmental improvement) in Moroto, Napak and Nabilatuk districts of the Karamoja region. 2. To identify the key barriers and facilitators influencing the implementation of the SAFE strategy for trachoma control in the selected districts.
Uganda 2026-08-11 20:21:31 2029-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Galiwango Dereck
ID: UNCST-2025-R019894
FINANCIAL RESOURCE MOBILISATION PATHWAYS AND FINANCIAL SUSTAINABILITY OF PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS4972ES

1. To examine the relationship between diversified resource mobilization pathways and financial sustainability in Public Universities Uganda.
2. To determine the mediating role of cost management practices on the relationship between diversified resource mobilization pathways and financial sustainability in public universities in Uganda.
3. To examine the mediating role and contribution of Planning and Finance department on the relationship between diversified resource mobilization pathways and financial sustainability in public universities in Uganda.

Uganda 2026-08-11 20:19:24 2029-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
Noel  Namuhani
ID:
A REALIST EVALUATION OF HOW AND UNDER WHAT CONDITIONS SOCIAL HEALTH PROTECTION CAN BE EXTENDED TO WORKERS IN THE INFORMAL ECONOMY IN UGANDA
REFNo: HS8331ES

4. To empirically examine the contextual conditions and mechanisms through which strategies used by the selected social health protection initiatives influence (not) coverage among informal workers in Uganda in order to refine the initial program theory.,3. To explore the hypothesized contextual conditions and mechanisms through which strategies used by the identified social health protection initiatives are expected to influence (not) coverage among informal workers in Uganda in order to develop an initial program theory. ,2. To explore strategies being implemented by the different social health protection initiatives and how they influence coverage among informal workers in the informal economy in Uganda. ,1. To identify and categorize the documented strategies for extending social health protection initiatives to workers in the informal economy in Sub-Saharan Africa. ,To explain how and in what conditions social health protection can be extended to workers in the informal economy in Uganda. ,
Uganda 2026-08-11 19:21:05 2029-08-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Ouma Simple
ID: UNCST-2021-R012820
Evaluation of electronic Community Health Information System (eCHIS) in Uganda
REFNo: HS8223ES

To evaluate the performance of eCHIS as an integrated digital health information system in Uganda.,4. To evaluate the implementation processes, adoption, fidelity, and sustainability of eCHIS implementation in Uganda.,To assess the budget impact and financial sustainability of scaling up eCHIS implementation to districts not currently implementing the system in Uganda.,To estimate the financial and economic costs of implementing and maintaining eCHIS and assess its cost implications for improving community health services in Uganda.,To determine the effect of eCHIS implementation on the uptake of childhood vaccination and other community health services in intervention districts compared with matched comparator districts in Uganda.,To evaluate the effectiveness, implementation determinants and outcomes, health information system performance, costs, and scalability of the eCHIS and its contribution to improving vaccination uptake and delivery of community health services in Uganda.,
Uganda 2026-08-11 19:12:24 2029-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Atwine Emmanuel Mignot
ID: UNCST-2026-R025405
EFFECT OF AGRICULTURAL COOPERATIVE INPUT SUPPLY AND EXTENSION SERVICES ON SMALLHOLDER COFFEE YIELDS IN NTUNGAMO DISTRICT, UGANDA
REFNo: SS5679ES

1. To examine smallholder coffee farmers’ perceptions regarding the contribution of agricultural cooperative-provided inputs and extension services to coffee productivity in Ntungamo District. 2. To evaluate the effect of cooperative-provided inputs and extension services on farmers’ adoption of improved and climate-smart farming practices. 3. To determine the relationship between the adoption of improved and climate-smart farming practices promoted through agricultural cooperatives and farmers’ perceived changes in coffee yields and income, while controlling for farm size, access to credit, and weather conditions.
Uganda 2026-08-11 17:24:22 2029-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
Namazzi Beepath Christine
ID: UNCST-2022-R011212
Utilizing Counselling services and the Bio-Psychosocial wellness of students in secondary schools. A case of Kampala and Wakiso districts of Uganda
REFNo: SS5716ES

1. To establish the relationship between bio-physical counselling and biopsychosocial wellness of students in selected secondary schools in Kampala and Wakiso Districts of Uganda. 2. To identify the influence of psycho-emotional counselling on biopsychosocial wellness of students in selected secondary schools in Kampala and Wakiso Districts of Uganda. 3. To investigate the role of social counselling on the biopsychosocial wellness of students in selected secondary schools in Kampala and Wakiso Districts of Uganda. 4. To determine the influence of vocational counselling on the biopsychosocial wellness of students in selected secondary schools in Kampala and Wakiso Districts of Uganda.
Uganda 2026-08-07 19:02:08 2029-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Doreen Nakagaayi
ID: UNCST-2023-R006587
Artificial Intelligence to Scale Early Rheumatic Heart Disease Detection
REFNo: HS8271ES

Aim 3: Compare service and implementation measures between standard non-AI echocardiography compared to the RADAR for RHD screening. ,Aim 2: Compare the screening accuracy of providers (nurses and nurse-midwives) using standard non-AI echocardiography interpretation compared to those using RADAR for RHD screening,Aim 1: Refine and optimize RADAR deployment, workflows, and training protocols,The overall objective of this project is to evaluate whether RADAR can overcome key barriers to scaling RHD screening�specifically, whether it maintains or improves screening accuracy compared to current approaches and how it can be successfully implemented in diverse low-resource settings�thereby establishing a model for global uptake. In Uganda, we will evaluate effectiveness and implementation of RADAR through a hybrid cluster randomized trial.,
Uganda 2026-08-07 19:00:15 2029-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Semitala Fred
ID: UNCST-2020-R014202
RAPID RESEARCH IN DIAGNOSTICS DEVELOPMENT FOR HIV+ (R2D2 HIVPLUS) STUDY
REFNo: HS8361ES

To determine the diagnostic performance of design-locked and prototype novel HIV VL and/or CD4 tests (“novel HIV tests”) compared to WHO-endorsed reference test.
Uganda 2026-08-07 18:58:15 2029-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
FACILITY ASSESSMENT OF SERVICE DELIVERY POINTS FOR REPRODUCTIVE HEALTH COMMODITIES IN UGANDA:
REFNo: HS8233ES

7. To appraise clients\' perception of family planning service provision and the cost of accessing these services.,6. To assess methods of waste disposal and the administration of user fees in SDPs.,5. To generate information on the use of Information Communication Technology (ICT) for commodity management.,4. To assess the availability and usability of national guidelines, protocols, and job aids at service delivery points.,3. To establish the status of staff training and supervision regarding family planning and RH service delivery.,2. To assess the supply chain processes, including cold chain capacity and logistics management information systems (LMIS).,1. To generate findings on the availability and stock-out status of RH commodities, including generic contraceptives and maternal/RH medicines.,To document progress in attaining reproductive health commodity security and in delivering quality services in Uganda, including in humanitarian settings.,
Uganda 2026-08-07 18:53:58 2029-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
Point prevalence survey of Hospital-Acquired Infections in Selected Facilities in Uganda.
REFNo: HS8360ES

Major Objective: To provide the first standardized estimate of the burden and characteristics of Hospital-AcquiredInfections (HAIs) in participating healthcare facilities and to establish a baseline for Uganda’s National HAI Surveillance Program.

Primary Objective:
• To determine the point prevalence of active Hospital-Acquired Infections (HAIs) among inpatients in participating healthcare facilities in Uganda.
Secondary Objectives:
1. To describe the distribution and types of major HAIs and to identify the highest-risk patient populations and hospital units.
2. To describe the etiology of HAIs by identifying the most common causative pathogens and their antimicrobial resistance patterns where microbiological data is available.
3. To assess key structural and process indicators for Infection Prevention and Control (IPC) at the facility and ward levels
4. To build national capacity for HAI surveillance by training a cohort of healthcare workers in standardized surveillance methodologies, case definitions, and data collection protocols.

Uganda 2026-08-07 18:38:26 2029-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Conrad Muhumuza
ID: UNCST-2025-R020343
ASSESSING THE IMPACT OF PHARMACIST-LED INTERVENTIONS IN IMPROVING MEDICATION ADHERENCE AMONG CHRONIC DISEASE PATIENTS; A PROSPECTIVE LONGITUDINAL STUDY AT KAYUNGA REGIONAL REFERRAL HOSPITAL.
REFNo: HS8142ES

1. To assess baseline medication adherence levels among patients attending the chronic care clinic at Kanyunga RRH.2. To implement pharmacist-led interventions (counseling, SMS reminders, refill synchronization) for chronic care patients at Kayunga RRH.
Uganda 2026-08-07 18:35:50 2029-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Boaz Mwesigye
ID:
Perceived Tax Enforcement Practices, Taxpayer Awareness, Motivational Postures and Tax Compliance among Small Taxpayers in Uganda
REFNo: SS5678ES

i. To examine the influence of perceived tax enforcement practices on taxpayer awareness, motivational postures and tax compliance among small taxpayers in Uganda. ii. To examine the influence of taxpayer awareness on tax compliance among small taxpayers in Uganda. iii. To examine the influence of motivational postures on tax compliance among small taxpayers in Uganda. iv. To assess the mediating role of taxpayer awareness in the relationship between perceived tax enforcement practices and tax compliance among small taxpayers in Uganda. v. To assess the mediating role of motivational postures in the relationship between perceived tax enforcement practices and tax compliance among small taxpayers in Uganda.
Uganda 2026-08-07 18:31:12 2029-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Okello Gilbert
ID: UNCST-2023-R008024
Indigenization of Information Services in Bukedi Subregion, Uganda
REFNo: SS4815ES

1. To establish the existing information services in Bukedi Subregion. 2. To examine the information service needs of Bukedi Subregion. 3. To determine the information service gaps in Bukedi Subregion. 4. To develop a framework for indigenization of information services in Bukedi Subregion.
Uganda 2026-08-07 18:17:33 2029-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Mathew Kabalega
ID: UNCST-2026-R027197
Program Outcomes Assessment of Mastercard Foundation Young Africa Works Interventions in Uganda: A Mixed-Methods Study of Youth Employment, Enterprise Development, and Systems-Level Contributions
REFNo: SS5759ES

Program Outcomes Assessment of Mastercard Foundation Young Africa Works Interventions in Uganda: A Mixed-Methods Study of Youth Employment, Enterprise Development, and Systems-Level Contributions
Uganda 2026-08-07 18:08:56 2029-08-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Comfort Vandu Danchal
ID: UNCST-2025-R021884
COMPARATIVE GENOMIC ANALYSIS OF CLINICAL AND HOSPITAL-ENVIRONMENT ISOLATES OF P. aeruginosa IN SELECTED HEALTHCARE FACILITIES IN ISHAKA-BUSHENYI MUNICIPALITY, UGANDA.
REFNo: HS7725ES

General objective: To characterize and compare the genomic features, antimicrobial resistance determinants, andvirulence genes of clinical and hospital environmental Pseudomonas aeruginosa isolates inselected healthcare facilities in Bushenyi Ishaka Municipality. Specific objectives: 1. To determine the prevalence of Pseudomonas aeruginosa among clinical and hospitalenvironmental samples in selected healthcare facilities in Bushenyi Ishaka Municipality. 2. To assess and compare the antimicrobial susceptibility profiles of P. aeruginosa isolatesfrom clinical and hospital environmental sources. 3. To identify and characterize antimicrobial resistance genes, virulence factors, and biofilm-associated genes in P. aeruginosa isolates. 4. To analyze and compare the genomic diversity, sequence types, and phylogeneticrelationships of clinical and hospital environmental P. aeruginosa isolates. 5. To compare the genomic profiles of local isolates with global reference strains to determineevolutionary relationships and potential emergence of high-risk clones.
Nigeria 2026-08-07 17:58:06 2029-08-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Charles GALABUZI
ID: UNCST-2026-R024664
UNLOCKING THE WOOD FUEL VALUE CHAIN’S POTENTIAL: CHARCOAL PRODUCTION IN UGANDA
REFNo: SS5356ES

a) To examine the regulatory and other contextual factors, socio-economic characteristics, and demographics of small-scale charcoal producers.
b) To assess charcoal production dynamics, arrangements, and the factors that influence small-scale charcoal production
c) To examine the gendered roles, places and spaces of small-scale charcoal producers with an intersectionality lens.
Uganda 2026-08-07 17:55:22 2029-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Eleku
ID: UNCST-2025-R021209
SMATCH-Soroti: Strengthening Maternal Antenatal Testing and Community Health for Hepatitis B in Soroti
REFNo: HS7460ES

Main objective: Determine the proportion of HBV-infected pregnant women eligible for TDF treatment under centralized (viral load ?10,000 IU/mL) and decentralized (HBsAg+) model. Specific objectives: 1. Assess HBsAg prevalence among pregnant women in Soroti (overall and by site). 2. Assess risk factors for HBsAg positivity. 3. Assess knowledge, and perceptions related to HBV among pregnant women. 4. Evaluate linkage to care and treatment adherence among HBsAg-positive women initiated on TDF; identify barriers to engagement. 5. Characterize maternal HBV DNA dynamics on TDF: reduction in viral load from baseline to delivery. 6. Compare costs of centralized versus decentralized models. 7. Calculate the incremental cost-effectiveness ratio as cost per modelled MTCT case averted (using literature-based transmission rates or maternal viral load as a proxy). 8. Quantify potential overtreatment in the decentralized model: proportion of women treated who would not meet the centralized viral load threshold (<10,000 IU/mL).
Uganda 2026-08-07 17:53:36 2029-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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