Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Juliet Sekandi Nabbuye
ID: UNCST-2026-R024828
Assessing The Impact of Post-Tuberculosis on Reproductive Health in Kampala, Uganda
REFNo: HS7745ES

Aim 1 — To assess the impact of a tuberculosis diagnosis on fertility by quantifying and comparing pregnancy incidence rates in women of reproductive age during the pre- and post-TB diagnosis periods.
Hypothesis 1.1: Compared with the pre-TB diagnosis period, the pregnancy incidence rate in the post-TB diagnosis period will be lower (incidence rate ratio [IRR] < 1.0).
Hypothesis 1.2: The pregnancy incidence rate in the immediate post-treatment period will be lower than the pregnancy incidence rate in the later post-treatment period.

Aim 2 — To estimate the prevalence of reproductive morbidity and the proportion of pregnancies resulting in adverse pregnancy outcomes among women of reproductive age following a tuberculosis diagnosis.

Aim 3 — To explore women’s knowledge, perceptions, and lived experiences regarding the influence of post-TB sequelae on reproductive health.


Uganda 2026-06-19 10:57:18 2029-06-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Filimin Niyongabo
ID: UNCST-2026-R023390
From Classrooms To Communities: Educating For Resilience Against Floods And Landslides In Mbale District, Uganda
REFNo: HS7625ES

1. To determine the levels of knowledge among teachers about climate change, floods, and landslides. 2. To explore teachers’ perceptions of the risks and impacts of floods and landslides in their communities. 3. To assess the practices employed by teachers in promoting resilience and preparedness against floods and landslides within their communities. 4. To design and develop educational materials to equip teachers and students with knowledge on floods and landslides resilience.
Uganda 2026-06-19 10:50:12 2029-06-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nimanya Stella Alice
ID: UNCST-2022-R009589
INTUSSUSCEPTION MONITORING IN UGANDA AFTER INTRODUCTION OF ROTASIIL VACCINE: SELF CONTROLLED CASE SERIES
REFNo: HS7519ES

1.To assess for the safety of Rotasiil vaccine under routine public health use among infants in Uganda
2.To assess for any potential association between the oral rotavirus vaccine (Rotasiil) and the development of intussusception in infants at Mulago National Referral Hospital during the study period.
Uganda 2026-06-19 10:45:07 2029-06-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Evaluation of the Clinical and Analytical Performance and Usability of the KHB HIV/Syphilis Combo Rapid Test in the Hands of the Intended User
REFNo: HS7852ES

Establish the performance of the KHB HIV/Syphilis Combo Rapid Test in accordance with WHO TSS-27 (draft). This study will not cover all the parts of the TSS-27 (draft) but will focus on: - Part 1 Analytical Performance and Other Evidence o Aspect 3.05.02 ‘Validation of specimens’ o Aspect 3.05.06a ‘Potentially Interfering Substances’, Endogenous o Aspect 3.05.06b ‘Cross-reactivity’ o Aspect 3.06.04b ‘Usability: Label comprehension study (including instructions for use (IFU))’ o Aspect 3.06.04c ‘Usability: Results interpretation study’ - Part 2 Clinical Evidence o Aspect 4.02.03 Device specific clinical studies,Establish the performance of the KHB HIV/Syphilis Combo Rapid Test in accordance with WHO TSS-1. This study will not cover all the parts of the TSS-1 but will focus on: - Part 1 Establishing Analytical Performance Characteristics o Aspect 1.1 ‘Specimen Type’ (1.1.1 and 1.1.2) o Aspect 1.7.1 ‘Potentially Interfering Substances’, Endogenous o Aspect 1.7.2 ‘Cross-reactivity’ - Part 2 Establishing Clinical Performance Characteristics o Aspect 2.1 ‘Diagnostic sensitivity and specificity’ (2.1.1, 2.1.2 and 2.1.3)his study will not cover all the parts of the TSS-1 but will focus on:,
Uganda 2026-06-12 3:54:05 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Peppe James
ID: UNCST-2026-R024831
Evaluating forest structure and climate in Arican tropical forests: A pilot study from Kibale National Park, Uganda
REFNo: NS1281ES

The overall goal of this project is to document forest structure, plant functional traits, and microclimate conditions in African tropical forests to improve understanding of ecosystem dynamics and climate interactions.
The specific objectives are:
(1) to quantify tree density and forest structure in two 1-hectare plots (old-growth and regenerating forest);
(2) to measure stem taper for characterization of tree form;
(3) to collect leaf trait data using standardized imaging methods; and
(4) to monitor microclimate conditions, including temperature and soil moisture, within each plot.
USA 2026-06-12 3:52:15 2029-06-12 Natural Sciences Non-Clinical Trial Non-degree Award
Sandra Nanyunja Nakityo
ID: UNCST-2026-R024003
Digital Literacy and Displacement: Shaping Inclusive Futures with Refugee Women in Uganda
REFNo: SS5352ES

The overarching aim of this study is to explore how actors, networks, and institutional imaginaries of digital literacy and technology in displacement contexts shape, enable, or constrain refugee women’s aspirations and everyday practices, and how this interplay can inform the pursuit of sustainable digital inclusion in Uganda. The specific objectives are: 1. To examine which actors and networks shape the digital literacy landscape for refugee women in Uganda, and how they influence this landscape. 2. To analyse in what ways policy and institutional documents present digital literacy for refugee women in Uganda. 3. To understand the main perceptions and aspirations of refugee women in Uganda about digital literacy. 4. To investigate how refugee women in Uganda conceptualize and use digital technology in their everyday life (including work). 5. To explore how the interplay between refugee women's aspirations and institutional imaginaries can inform sustainable digital inclusion.
Uganda 2026-06-12 3:51:19 2029-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
JaiBum Koo
ID: UNCST-2026-R023919
Teacher upskilling through Uganda’s National Teacher Policy: A vertical case study of policy implementation, systemic change, and classroom practice
REFNo: SS5307ES

The purpose of this study is to examine teacher upskilling under Uganda’s National Teacher Policy (NTP) using a vertically integrated, three-level design. The study seeks to understand how the upskilling policy is developed and implemented across national, institutional, and teacher levels.
South Korea 2026-06-12 3:48:26 2029-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Apurva Bhatnagar
ID: UNCST-2026-R024225
Evaluating the Effects of StrongMinds Community-Based Group Interpersonal Therapy on Depression and Secondary Outcomes in Uganda: A Cluster Randomized Controlled Trial
REFNo: SS5286ES

This study aims to evaluate the impact of the StrongMinds IPT-G model on depressive symptoms (primary outcome) and measures related to quality of life, social, economic, and educational outcomes (secondary outcomes).
India 2026-06-12 3:47:18 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
Clinical Performance Evaluation of Novel Rapid Molecular Point-of-Care (POC) Diagnostics for Mpox Virus
REFNo: HS7690ES

To compare performance of the index test results by identified virus clade(s) circulating in-country. To determine the association of the index tests sensitivity results with Ct values (as a proxy for viral load). To determine the diagnostic performance of mpox POC tests (index tests) vs. gold-standard PCR (reference test) on archived lesion specimens Mpox-positive and negative.
Uganda 2026-06-12 3:45:18 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Perrine Theroude Margaux Colombe
ID: UNCST-2026-R025247
Face Value: Behavioural and Bio-Psychological Monitoring of Great Ape Wellbeing
REFNo: NS1267ES

Primate health: Innovating via state-of-the-art technology to obtain non-invasive and unobtrusive real-time biological measures markers of stress.
This project aims to investigate the relationship between stress-related
behaviours, and changes in facial temperature in captive and wild chimpanzees using infrared thermography.
France 2026-06-12 3:43:28 2029-06-12 Natural Sciences Non-Clinical Trial Degree Award
Soofia Mahmood
ID: UNCST-2025-R022700
DATA-DRIVEN TARGETING AND ADAPTATIONS FOR SCALING ULTRA POVERTY GRADUATION (UPG) IN MID WEST AND SOUTH WESTERN UGANDA
REFNo: SS5421ES

1. To assess whether data-informed prioritization of vulnerable households for individual coaching check-ins improves practice adoption and household economic outcomes. 2. To compare group enterprise investment and individual lending models in building sustainable for women-led Village Savings and Loan Associations (VSLAs) and improving economic outcomes for members. 3. To evaluate whether government staff can deliver household coaching with effectiveness compared to RTV staff when using the same tools and implementation approach.
Canada 2026-06-12 3:42:23 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Elisabeth Gerwing-Adima
ID: UNCST-2026-R025356
Determining the Burden and Drivers of Stigma and Mental Health Among Individuals with Lived Experience of Leprosy in Uganda.
REFNo: HS7717ES

General objective
The general objective of this study is to determine the burden and the drivers of mental health burden and stigmatization of those affected by leprosy in Uganda, to inform policy makers and enable effective intervention development. Specific objectives:1. To assess the mental health burden among people affected by leprosy in Uganda, by investigating both the burden of the mental distress (quantitative) and the lived experiences of patients (qualitative).
2. To determine the burden of leprosy-related stigmatization in the Mayuge district, Uganda (quantitative), and explore in-depth how leprosy stigmatization is experienced (qualitative).


Germany 2026-06-12 3:40:43 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Nabayinda
ID: UNCST-2026-R023998
Examining the intersection of climate change and Intimate partner violence among young women living with HIV
REFNo: SS5395ES

General Objective: The overall objective of the study is to examine how climate-induced disasters interact with IPV, poverty and mental health to influence ART adherence among YWLHIV in Eastern Uganda. Specific Objectives: 1) To Quantitatively assess the extent to which poverty and mental health mediate the relationship between climate-induced disasters and IPV among YWLHIV in Eastern Uganda; 2) Qualitatively explore young women’s lived experiences and stake holders perspectives of how climate-induced disruptions (e.g., disasters, resource scarcity) affect access to HIV treatment and adherence.
Uganda 2026-06-12 17:17:32 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sheila Bamweyana
ID: UNCST-2026-R024037
HPTN 104: A multisite, open-label, randomized crossover study comparing adherence to a single daily dual prevention pill (DPP) versus FTC/TDF and Combined Oral Contraception separate pill dosing (2PR), given for pre-exposure prophylaxis and pregnancy prevention in women.
REFNo: HS7679ES

Primary Objective(s):
-Compare PrEP adherence to the DPP versus 2PR during a randomized crossover period.


Secondary Objectives:
-Compare PrEP adherence to the DPP versus 2PR during a Choice period.

-Evaluate acceptability of DPP versus 2PR during crossover and Choice periods.

-Evaluate preferences for the DPP versus 2PR.

-Compare PrEP persistence on the DPP versus 2PR during the Choice period.

-Compare the tolerability, side effects and unintended consequences (e.g., Intimate Partner Violence [IPV], pregnancy, HIV) of DPP versus 2PR: overall, during crossover and Choice periods.


Exploratory Objective:
-Examine facilitators and barriers of DPP adherence, acceptability, and persistence, during the crossover period and during Choice periods.

-Use mathematical modeling to estimate the effectiveness of the DPP and 2PR in reducing HIV incidence within the study cohort during the crossover and Choice periods.


Uganda 2026-06-12 17:15:26 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Musiime -
ID: UNCST-2021-R013794
The AWARE-Kampala Study (Air Pollution and Well-Being: Assessing Risks and Enhancing Education among adolescents in Kampala)
REFNo: SS5260ES

The overarching objective is to understand knowledge, attitudes, and perceptions of air pollution and health among adolescents in Kampala using focus group discussions grounded in the Health Belief Model.
Uganda 2026-06-12 17:08:59 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frances Imokol
ID: UNCST-2026-R024413
Longitudinal Study on Teacher and School Leader Self-Efficacy in support of VVOB Uganda’s Learning Entrepreneurship and Agriculture Practically (LEAP) initiative.
REFNo: A768ES

The Green LEAP longitudinal studies have been designed to generate robust insights into how teachers’ and school leaders’ self-efficacy evolves through both pre-service and in-service training.
Uganda 2026-06-12 17:01:04 2029-06-12 Agricultural Sciences Non-Clinical Trial Non-degree Award
Jolly Magulu
ID: UNCST-2021-R013833
Community Mental Health and the Role of Village Health Teams in Uganda: Challenges, Intervention Acceptability, and Sustainability in Mukono District: A Case Study of Omni Med Uganda
REFNo: HS7449ES

1. To find out the challenges faced by VHTs in delivering community mental health services in Mukono District.
2. To understand community members’ and VHTs’ perceptions regarding the role of VHTs in providing psychosocial support services in Mukono District.
3. To describe community members' and VHTs’ perspectives on the acceptability, feasibility, and relevance of the SEEK-GSP intervention in Mukono District.
4. To understand the perceived implications of USAID’s withdrawal of funding on the sustainability and continuity of community mental health interventions in Uganda.

Uganda 2026-06-12 16:59:26 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maren Mickeler Alana
ID: UNCST-2024-R003691
Generative AI in Knowledge Work: Experimental Evidence from Uganda
REFNo: SS5275ES

1. Causally identify how GenAI adoption changes knowledge work, focusing on workplace interactions and productivity, 1.1. Estimate the effect of GenAI on individual task performance (e.g., speed, quality, accuracy), 1.2. Estimate the effect of GenAI on interactions with colleagues and supervisors when executing knowledge-intensive tasks (volume, information exchange, quality of interactions), 1.3. Assess broader organizational implications, including firm-level productivity and supervisory load.
Germany 2026-06-12 16:57:06 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine Katusiime
ID: UNCST-2026-R024829
Knowledge, Attitudes and Prevention Practices Among Parents of Children with Rheumatic Heart Disease at Uganda Heart Institute.
REFNo: HS7675ES

1.To assess the level of knowledge of parents of children with Rheumatic Heart Disease at Uganda Heart Institute.
2.To assess the attitudes of parents of children with Rheumatic Heart Disease at Uganda Heart Institute.
3.To determine the preventive practices undertaken by parents of children with Rheumatic Heart Disease at Uganda Heart Institute.
4.To determine the relationship between knowledge, attitudes, and preventive practices of parents of children with Rheumatic Heart Disease at Uganda Heart Institute.

Uganda 2026-06-12 16:55:39 2029-06-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Richard Ssewakiryanga
ID: UNCST-2026-R023427
PSP ACTION-RESEARCH ON ‘REPRESENTATION, NEGOTIATION AND SOCIAL DIALOGUE IN THE INFORMAL ECONOMY’
REFNo: SS5206ES

a) To document the formal or informal practices related to representation in social dialogue and other forms of structured negotiations are currently present in the hospitality sector in Uganda.
b) To understand in what ways workers in informal employment engage in other/alternative forms of organising and negotiations to improve their working conditions.
c) To document the role of development partners in organizing and enhancing unions’ capacities to integrate and address informal workers’ issues.
d) To analyse the extent to which studies and other forms of evidence impact social dialogues and actors in the tourism and hospitality sectors.

Uganda 2026-06-12 16:49:53 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
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