Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Abdul Malik Muwanga
ID: UNCST-2026-R024094
Developing Leadership Skills of ECCE Center Management Committees in Palorinya Refugee Hosting ECCE centers - Obongi District
REFNo: SS5010ES

1 Identify gaps in the leadership skills of CMCs in refugee hosting ECCEcenters in Palorinya refugee settlement.
2 Develop a training program to strengtheb the leadership skills of CMCs in enhancing children’s learning outcomes in Palorinya refugee settlement.
3 Implement a training program to develop the leadership skills of CMCs to improve children’s learning outcomes in refugee-hosting ECCE centers in Palorinya.
4 Evaluate the effectiveness of a training program in developing the leadership skills of ECCECenter Management Committees to improve children’s learning outcomes in Palorinya refugee settlement.
5 Generate principles to guide the development and implementation of training programs for developing the leadership skills of CMCs to improve children’s Early Learning Outcomes (ELOs) in ECCEcenters in related poly-crisis contexts.

Uganda 2026-03-24 8:59:47 2029-03-24 Social Science and Humanities Clinical Trial Degree Award
Annet Adong
ID:
Leveraging contract farming and matching refugees to host landlords to improve refugee resilience and livelihoods in Uganda
REFNo: SS4994ES

• To assess the acceptability of the contracts and any modifications required, ,
• To understand potential frictions, failures, and constraints of contract farming
• Understand host landlord beliefs towards efforts to improve refugee livelihoods potential insights into whether shared economic activities can shift host communities from a zero-sum mindset
• Assess intervention delivery costs to inform a larger study.

Uganda 2026-03-24 8:56:09 2029-03-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
SARAH NAKANAABI
ID: UNCST-2026-R023326
MORPHOLOGICAL AND BACTERIOLOGICAL INVESTIGATIONS ON LESIONS AT THE ILEOCECAL JUNCTION AND THE ASSOCIATED LYMPH NODE IN CATTLE SLAUGHTERED AT CITY ABATTOIR, KAMPALA.
REFNo: A738ES

General objective

To characterize the lesions at the ileocecal junction and the associated mesenteric lymph nodes of cattle, determine their prevalence, and identify the bacterial pathogens associated with these lesions.

Specific objectives

To characterize the gross and microscopic lesions at the ileocecal junction and the associated lymph nodes and their prevalence.

To determine the bacterial causes of inflammatory lesions at the ileocecal junction and the associated lymph nodes.

Uganda 2026-03-24 8:54:42 2029-03-24 Agricultural Sciences Non-Clinical Trial Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
Smart discharges to improve post-discharge health outcomes in newborns with suspected sepsis
REFNo: HS7242ES

1. Phase I: To develop clinical risk prediction models for death up to 6-months post-discharge, among newborns 0 to 7 days of age admitted to a neonatal hospital unit with sepsis.
2. Phase II: To identify risk factors for developmental delays at 18 months in newborns 0 to 7 days of age admitted to a neonatal hospital unit with sepsis.
3. Phase III: To characterize the experience of and gaps in discharge and post-discharge care for newborns 0 to 7 days of age admitted to a neonatal hospital unit with sepsis.
4. Phase IV: To analyze host inflammatory response and pathogen biomarkers during illness in a subset of newborns 0 to 7 days old with sepsis, through the collection of blood samples and blood cultures.

Uganda 2026-03-24 8:53:43 2029-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
CD4 Testcard Digital Reader Study for VISITECT® CD4 Advanced Disease Testing in Uganda
REFNo: HS7194ES

Evaluate improvements in kit traceability, including visibility of lot numbers, expiry dates, and test-kit linkage to results.,Assess improvements in test-level traceability, including visibility of test counts, site locations, and test operators, comparing pre- and post-CD4R implementation.,Evaluate changes in user competency requirements and training processes, based on process mapping before and after implementation of the CD4R.,Assess whether the implementation of the CD4R improves standardization of test results by reducing error in test administration and interpretation. ,Assess staff-reported usability and workflow burden associated with the CD4 test, comparing pre- and post-CD4R implementation.,To assess the impact of digitalization on the result interpretation of the VISITECT® CD4 Advanced Disease test using the TestCard CD4 Digital Reader in Uganda,
Uganda 2026-03-24 8:50:52 2029-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Racheal Angom
ID: UNCST-2023-R007485
Appropriateness, Acceptability, Feasibility, and Usability of an Electronic Medical Records System for Improving Diagnostic Processes and Multidisciplinary Care for Children and Adolescents with Cancer in Uganda: An Implementation Science Approach.
REFNo: HS7249ES

1.Identify barriers and facilitators to EAFYA implementation.
2.Co-design, test, refine, and implement EAFYA-supported diagnostic and MDT pathways.
3.Evaluate implementation success by assessing usability, appropriateness, acceptability, and feasibility.

Uganda 2026-03-19 16:19:07 2029-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Evaluation of The Safety, Efficacy and Stability of SangaDelta® Emulsifiable Concentrate [E.C]: A Randomised Single-Blinded Positive Controlled Multi-Site Acaricide Field Trial
REFNo: NS1194ES

General objectives
To determine the efficacy, safety, and stability of SangaDelta® (Sanga Vet. Chem. Ltd, Kampala Industrial Park, Namanve ) when applied onto cattle by hand spraying and plunge dipping for tick control.

Specific objectives
The specific objectives of this acaricide field trial will to determine:
i.Efficacy of SangaDelta® when applied onto cattle by hand spraying and plunge dipping for tick control.
ii.Safety of SangaDelta® when applied onto cattle by hand spraying and plunge dipping for tick control.
iii.Stability of SangaDelta® when applied onto cattle by plunge dipping for tick control.

Uganda 2026-03-19 16:13:37 2029-03-19 Natural Sciences Clinical Trial Non-degree Award
Jane Frances ABODO
ID: UNCST-2026-R023717
The 48-Hour Rule on Arraignment of Suspects in Uganda: An Analysis Under International Human Rights Law
REFNo: SS5047ES

(i) To analyze the key differences and similarities between arrest in the laws of Uganda and International Human rights law. (ii) To analyze key differences and similarities between legal representation in the laws of Uganda and international human rights law. (ii) To analyze the key differences between the nature of crime in the laws of Uganda and international human rights law. (iv) To analyze the factors that affect the alignment of the 48-hour rule in the laws of Uganda to international human rights law.
Uganda 2026-03-19 16:09:10 2029-03-19 Social Science and Humanities Non-Clinical Trial Degree Award
Daniel Mwandah Chans
ID: UNCST-2022-R008880
DEVELOPMENT AND OPTIMIZATION OF ANTIBIOTIC TREATMENT ALGORTHM FOR THE ICU AMID ANTIBIOTIC RESISTANCE: INSIGHTS FROM MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS7191ES

4. To develop and validate an antimicrobial optimization tool using biomarkers and antimicrobial Susceptibility data,3. To determine key resistance genes in MDROs from isolates collected among ICU patients in South Western Uganda using PCR.,2. To determine the prevalence, associated factors and patient outcomes among ICU patients with MDROs at ICU of MRRH,1. To conduct a systematic literature review on prevalence, factors associated with, mortality rate, patient outcomes and mechanisms of resistance of MDROs in ICUs in Sub Saharan Africa,The main aim of this proposal is to study MDROs in the ICU of MRRH and optimizing antimicrobial therapy to improve patient outcomes by determining utilization of biomarkers (PCT and CRP) and antibiotic susceptibility tests (ASTs).,
Uganda 2026-03-19 16:07:23 2029-03-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Adoke Yeka
ID: UNCST-2021-R004300
A Phase 2A study to evaluate the safety, tolerability and pharmacokinetics of a novel antimalarial pyrrolidinamide at different doses and dose durations, in adult patients with uncomplicated P. falciparum malaria
REFNo: HS7237ES

Primary objective:
To investigate the safety and tolerability of GSK3772701 after single and repeat oral doses in adult patients with uncomplicated P. falciparum malaria.
Secondary objectives
To evaluate the PK profile of single and repeat oral doses of GSK3772701 in adult patients with
uncomplicated P. falciparum malaria.

Exploratory objectives.
1. To evaluate the efficacy of single and repeat oral doses of GSK3772701 in adult patients with uncomplicated P. falciparum malaria.
2. To characterize the PK/PD relationship.
3. To evaluate P. falciparum genetic polymorphisms and potency of GSK3772701.
4. To assess the safety of GSK3772701 for individual parameters after single and repeat oral doses in adult patients with uncomplicated P. falciparum malaria

Uganda 2026-03-19 16:01:49 2029-03-19 Medical and Health Sciences Clinical Trial Non-degree Award
Abubakar Muhammad Ndagi
ID: UNCST-2025-R023003
RELIGIOUS COMMITMENT, SOCIAL SUPPORT, RESILIENCE, AND PSYCHOLOGICAL WELL-BEING AMONG UNIVERSITY STUDENTS IN EASTERN UGANDA
REFNo: SS4943ES

1. To assess different levels of university student' religious commitment 2. To explore the characteristics of social support of university students 3. To assess the psychological well-being of university students 4. To analyze the relationship between religious commitment and psychological well-being 5. To analyze the relationship between social support and psychological well-being 6. To develop an integrated model of the relationships between religious commitment, social support, resilience, psychological well-being
Nigeria 2026-03-19 15:45:01 2029-03-19 Social Science and Humanities Non-Clinical Trial Degree Award
Emmanuel Wegoye
ID: UNCST-2024-R003214
Epilepsy Surgery in Uganda: Developing a Model for Accelerating Multi-disciplinary Epilepsy Care.
REFNo: HS7202ES

To assess our hybrid multidisciplinary, multi-institutional and transcontinental epilepsy program model in relation to improvement in DRE patient outcomes and local skills transfer (January 2021- June 2025) 1.2.2 Specific Objectives 1. To describe the clinical characteristics of patients with DRE and those who had epilepsy surgery at CCHU from January 2021 to June 2025 2.To describe the clinical outcomes of patients with DRE who had epilepsy surgery at CCHU from January 2021 to June 2025 3. To describe the capacity building and skills transfer at CCHU following the hybrid programme implementation in 2021.
Uganda 2026-03-19 15:10:33 2029-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Balinda RolandMujungu
ID: UNCST-2026-R023785
Development of an electricity sharing system for smart energy meters in Uganda.
REFNo: SIR621ES

1. To develop, within 6 months, a functional hardware prototype of a smart electricity metering system capable of supporting secure energy unit sharing and transfer between consumers.

2. To develop and integrate, within 9 months, a USSD-based module that enables remote, real-time energy unit sharing and balance transfer between smart meters, accessible to both smartphone and feature phone users.

3. To develop and integrate, within 9 months, a web-based application platform that provides advanced features for energy sharing, detailed transaction history, meter management, and secure unit transfer for customers using blockchain.

Uganda 2026-03-19 15:09:35 2029-03-19 Engineering and Technology Non-Clinical Trial Non-degree Award
Rogers Kasirye
ID: UNCST-2026-R023964
Understanding Youth Experiences and Preventing Sexual Exploitation in Uganda
REFNo: SS4969ES

1 To understand the experience of youth sexual exploitation through critical ethnographic conversations with survivors 2 To explore the perceived causes and possibilities for prevention of youth sexual exploitation through key informant interviews and fuzzy cognitive mapping with survivors and other stakeholders in communities. 3 To pilot a questionnaire survey to collect quantitative data about perceptions, prevalence and factors associated with youth sexual exploitation in Uganda.
Uganda 2026-03-19 15:04:21 2029-03-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Timothy Kintu Mwanje
ID: UNCST-2021-R013684
Development of a bi-lingual English-Luganda health dataset to enhance development of Natural Language Processing based applications for low resource language settings.
REFNo: HS6383ES

To coalesce and harmonize existing English and Luganda health-education documents into a unified parallel corpus for downstream NLP model development.,To explore and characterize the health-specific Luganda lexicon used by healthcare providers and community health workers ,To collect naturalistic Luganda-language speech from routine health-education sessions in central Uganda. ,To develop a bilingual English–Luganda health-related corpus for biomedical NLP applications.,
Uganda 2026-03-19 15:00:04 2029-03-19 Medical and Health Sciences Non-degree Award
Medard Twinamatsiko
ID: UNCST-2024-R003519
Improved Conservation Practices for the Environment and Natural Resources in South Western Uganda
REFNo: SS4413ES


1. To integrate equitable governance principles into natural resource and environmental conservation.
2. To determine the socio-ecological drivers and extent of degradation of river systems to inform their restoration.
3. To enhance the integration of Indigenous People in the management and conservation of natural resources.

Uganda 2026-03-19 14:54:42 2029-03-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan Nakubulwa Kiwanuka
ID: UNCST-2021-R013399
Barriers and facilitators of access to Hepatitis B immunization and treatment services among women of reproductive age in Bidibidi refugee settlement in Northern Uganda
REFNo: HS6695ES

i) To investigate barriers to and facilitators of access to Hepatitis B immunization and treatment services by women of reproductive age in Bidibidi settlement ii) To recommend areas for intervention to improve service delivery for Hepatitis B immunization and treatment in this population.
Uganda 2026-03-19 14:40:52 2029-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Halima Osman Ahmed
ID: UNCST-2025-R017652
BACTERIAL VAGINOSIS: PREVALENCE, ANTIBACTERIAL SENSITIVITY PATTERN AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS7127ES

1. To determine the prevalence of bacterial vaginosis among pregnant women attending antenatal care at Mbarara Regional Referral Hospital.
2. To determine the factors associated with bacterial vaginosis among pregnant women attending antenatal care at Mbarara Regional Referral Hospital.
3. To describe the antibacterial sensitivity patterns of bacterial with bacterial vaginosis among pregnant women at Mbarara Regional Referral Hospital.

Somalia 2026-03-19 14:34:19 2029-03-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
Evaluating the test-taking experience, feasibility, and acceptability of the FLI-11 in preparation for Uganda’s first nationwide mental health survey
REFNo: HS7016ES

3. To identify barriers and facilitators to the successful implementation of the FLII-11 as a nationwide population-based survey for mental disorders in the Ugandan health and research settings.,2. To gain insights and perspectives from healthcare workers, mental health experts, policymakers and lived experts on implementing a nationwide population-based survey for mental disorders in Uganda using the FLI-11 tool,1. To evaluate the administration experience, feasibility and acceptability (cultural appropriateness, comfort, content, language, length, relevance and willingness to use) of administering the FLII-11 tool in routine diagnostic assessments among patients, their caregivers and healthcare workers in Uganda.,To evaluate the test-taking, administration experience, feasibility and acceptability of the FLII-11 for diagnostic assessments in Uganda.,
Uganda 2026-03-19 14:32:27 2029-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Flavia Namiiro
ID: UNCST-2024-R005009
Developing an information package to improve knowledge sharing on preterm birth among pregnant women attending the antenatal clinic at Mulago Specialized Women’s & Neonatal Hospital Kampala Uganda.
REFNo: HS7041ES

1. To assess the level of knowledge and associated factors among health providers and pregnant women at Mulago Specialized Women’s & Neonatal Hospital (MSWNH).
2. To explore the “preference and perception of knowledge sharing” about preterm birth during pregnancy as perceived by mothers with surviving preterm infants at MSWNH
3. To iteratively co-design an information package to improve knowledge sharing on preterm birth during the antenatal period.
4. To pilot an information package designed to improve knowledge on preterm birth during the antenatal period at MSWNH.

Uganda 2026-03-19 14:25:42 2029-03-19 Medical and Health Sciences Non-Clinical Trial Degree Award
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