Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
George William Barigye
ID: UNCST-2025-R019843
 The Multifaceted Influence of Media on Family Planning Decisions: A Mixed-Methods Study in Kampala, Uganda.
REFNo: HS6961ES

General Objective: • To determine the influence of diverse media channels on family planning decisions among men and women in Kampala. Specific Objectives: 1. To identify the primary media sources (mass media, social media, interpersonal communication, etc.) utilized by men and women in Kampala to obtain information on family planning. 2. To assess the accuracy and trustworthiness of family planning information obtained from these diverse sources, and how these perceptions vary across gender and media type. 3. To determine the association between exposure to different media messages about family planning and the uptake of family planning methods among men and women, considering the influence of different media channels. 4. To explore gender differences in media usage patterns, perceptions of information accuracy, and uptake of family planning methods.
Uganda 2026-02-02 18:42:55 2029-02-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Nicholas Omoding
ID: UNCST-2025-R022323
 Strengthening Agroecology-based School and College Food Procurement Programs in East and Southern Africa
REFNo: A696ES

General Objective The project aims to achieve two overarching goals: first, to improve learners’ access to healthy and nutritious food by strengthening local, agroecological school food procurement practices, ensuring consistent, diverse, and nutrient-rich meals while supporting local farmers and resilient food systems; and second, to drive policy transformation for sustainable and inclusive school feeding by promoting gender equality and social inclusion and integrating agroecological principles, local sourcing, and participatory governance into school food policies. Specific Objectives 1. To improve the understanding of how existing school feeding systems affect income generation, gender equality and inclusion, climate resilience, and local food security, through participatory action research in selected schools. 2. To pilot and refine agroecology-based school feeding models in collaboration with schools, communities, and smallholder farmers to test their effectiveness and feasibility. 3. To increase women’s and youth empowerment through enhanced participation and decision-making in the governance of local school food systems and agroecological food value chains. 4. To generate evidence-based recommendations for policy integration and scaling of successful agroecology-based school feeding models to promote sustainable, inclusive, and agroecologically informed school feeding programmes.
 Uganda 2026-02-02 18:40:40 2029-02-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Mélissa Berthet
ID: UNCST-2025-R022378
 Commitment to joint action in chimpanzees and gorillas
REFNo: NS1125ES

The goal of the project is to investigate how wild chimpanzees and wild mountain gorillas signal and maintain their joint commitment to joint behavioural actions (for example, travelling together or defending territory).
 France 2026-02-02 18:37:54 2029-02-02 Natural Sciences Non-Clinical Trial Non-degree Award
Isaac Ebiju
ID: UNCST-2024-R003903
 ASSESSING THE SELF-REPORTED EFFECT OF HERBAL MEDICATION USE ON ADHERENCE AND SELF-CARE AMONG HYPERTENSIVE PATIENTS AT JINJA REGIONAL REFERRAL HOSPITAL, EASTERN UGANDA: A MIXED-METHODS STUDY
REFNo: HS6932ES

General Objective To assess the self-reported effect of herbal medication use on adherence and self-care among hypertensive patients in Jinja Regional Referral Hospital, Eastern Uganda. Specific Objectives 1. To assess the Patient Adherence and self-care levels among hypertensive patients attending outpatient care in Jinja Regional Referral Hospital, Eastern Uganda. 2. To assess the effects of socio-demographic and individual associated with herbal medication on adherence and self-care among hypertensive patients attending outpatient care in Jinja Regional Referral Hospital, Eastern Uganda. 3. To assess the clinical factors associated with herbal medication on adherence and self-care among hypertensive patients attending outpatient care in Jinja Regional Referral Hospital, Eastern Uganda. 4. To explore the beliefs, perceptions, barriers, and motivations regarding the use of herbal medications and the influence on their adherence to treatment and engagement in self-care practices among hypertensive patients attending outpatient care in Jinja Regional Referral Hospital, Eastern Uganda.
Uganda 2026-02-02 18:37:03 2029-02-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Samantha  Winter C
ID: UNCST-2024-R002966
 Investigating direct and indirect pathways between climate and mental health and wellbeing and development and testing of localized, impact-based early warning systems for climate vulnerable communities in Uganda, Tanzania, and Kenya
REFNo: SS4713ES

Objective 1:
To analyze and compare the prevalence and frequency of extreme weather events (EWEs) in 18 vulnerable communities using triangulated meteorological data from public sources and data collected from local weather stations over a 9-month baseline period.

Objective 2:
To conduct monthly household-level surveys with 103 women from each of the 18 communities to document their experiences of EWEs, thereby developing localized impact-based thresholds that reflect the specific impacts of these events on community members.

Objective 3:
To examine the relationships between climate conditions, as indicated by the impact-based thresholds from Objective 2, and measures of mental health, well-being, and interpersonal violence using modified vector autoregressive (VAR) analysis on data collected from monthly surveys.

Objective 4:
To implement a step-wedge cluster randomized control trial assessing the effects of a localized early warning system (EWS) on women's mental health, well-being, and interpersonal violence in the 18 vulnerable communities, with half receiving the EWS for the first 9 months and all receiving it for the subsequent 9 months.
 USA 2026-02-02 18:35:30 2029-02-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Kamiza Patrick
ID: UNCST-2025-R020340
 Organizational Justice, compassionate Leadership, Career Motivation and Compensation satisfaction among Academic Staff in Public Universities in Uganda.
REFNo: SS4555ES

i) examine the relationship between organizational justice and compensation satisfaction amongst staff in public universities in Uganda:
ii) assess the relationship between compassionate leadership and compensation satisfaction amongst academic staff in public universities in Uganda;
iii) examine the relationship between career motivation and compensation satisfaction amongst academic staff in public Universities in Uganda;
iv) determine the relationship between organizational justice and career motivation amongst academic staff in public universities in Uganda;
v) examine the relationship between compassionate leadership and career motivation amongst academic staff in public universities in Uganda;
vi) examine the mediating role of career motivation on the relationship between organisational justice and compensation satisfaction;
vii) examine the mediating effect of career motivation in the association between compassionate leadership and compensation satisfaction.

 Uganda 2026-02-02 18:33:41 2029-02-02 Social Science and Humanities Degree Award
Vidhya Sivanantham
ID: UNCST-2026-R023441
 Unpacking the Work of Healthcare Providers in Short-Term Medical Missions: An Institutional Ethnography Study in Uganda
REFNo: HS7011ES

The overall aim of the study is to examine how healthcare provider work is socially and institutionally organized during short-term medical and dental outreach in Kalangala District, Uganda.

The specific objectives are to:
1. Map existing evidence on how short-term medical and dental missions organize provider roles and workflows through a scoping review.
2. Explore how institutional texts (e.g., protocols, referral tools, policies) and local practices shape day-to-day decision-making among local and visiting providers. 3. Analyze how decision-making hierarchies and communication structures influence care delivery and interprofessional collaboration across local and international teams.
 Canada 2026-02-02 12:10:35 2029-02-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Julius Lutwama Julian
ID: UNCST-2021-R011979
 PBMC Collection from Rift Valley Fever Survivors in support of LARISSA II-Uganda
REFNo: HS6772ES

The Primary Objective of this study is to assess the T cell responses in RVF survivors and correlate it with disease severity and humoral immunity.
Specific Objectives
1. The Secondary Objective includes the generation of supportive information for interpreting immunogenicity results coming from RVF vaccine clinical trials.
2. Potential future exploratory objectives include B and T-cell sequencing to identify patterns of RVFV-specific immune responses and isolation of therapeutic antibody candidates

 Uganda 2026-01-30 9:58:04 2029-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Bosco Ddamulira Mayanja
ID: UNCST-2022-R010819
 Analysis of the current state of HIV-related stigma and discrimination in Uganda: A cross-sectional survey of the magnitude, drivers and facilitators, and effect on HIV prevention and care services.
REFNo: HS6886ES

1. To determine the magnitude of HIV-related stigma and discrimination manifestations among people living with HIV.
2. To identify the drivers and facilitators of HIV-related stigma and discrimination at family, community and health facilities.
3. To assess the association between HIV-related stigma and discrimination and HIV prevention and care services including disclosure, engagement in care, adherence to treatment, and viral suppression.
4. To document PLHIV’s lived experiences of HIV-related stigma and discrimination.

Uganda 2026-01-30 9:54:54 2029-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lucrezia Rovati
ID: UNCST-2025-R021085
 Evaluation of a Clinical Decision-Support App for Emergency Care in a Rural Ugandan Hospital: A Pilot Randomized Crossover Simulation Trial
REFNo: HS6836ES

The primary objective is to determine whether the newly developed OASES clinical decision-support App improves frontline clinicians’ adherence to evidence-based World Health Organization (WHO) and Uganda Clinical Guidelines during the management of simulated emergency cases of diarrhea, dyspnea, and seizures in a rural outpatient department. The secondary objectives are to assess whether the OASES App improves triage accuracy using the Interagency Integrated Triage Tool, diagnostic accuracy at both the initial and post-investigation stages, and the appropriateness of disposition decisions; to determine whether App use enhances clinicians’ process quality by increasing adherence to guideline-recommended history taking and physical examination; to compare time required to complete simulated emergency cases under App-assisted versus standard practice conditions; to evaluate usability, perceived usefulness, trust, satisfaction, and feasibility of the App through structured questionnaires and qualitative interviews.
 Italy 2026-01-30 9:27:17 2029-01-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Nicholas Mutegyeki
ID: UNCST-2025-R021685
 EXAMINATION OF CORPORATE GOVERNANCE IN MILITARY ENTERPRISES IN UGANDA
REFNo: SS4701ES

General objective
The general objective is to examine corporate governance in military enterprises in Uganda.
1.4.2 Specific objectives
The specific objectives of this study are:
v) To examine the legal framework governing military enterprises in Uganda.
vi) To analyse the applicability of corporate governance principles in military enterprises in Uganda.
vii) To assess the legal and institutional inhibitions to the implementation of effective corporate governance in military enterprises in Uganda.
viii) To compare the legal framework on corporate governance in military enterprises in Uganda to other jurisdictions.

 Uganda 2026-01-30 9:07:16 2029-01-30 Social Science and Humanities Non-Clinical Trial Degree Award
victoria nakibuuka
ID: UNCST-2020-R014741
 African Neonatal Network: a Collaborative Quality Improvement and Leadership Development Community working to improve neonatal outcomes.
REFNo: HS2963ES

Aim: Improvement in neonatal mortality among patients admitted to participating ANN inpatient neonatal units.

Objectives:
• Engage ANA leaders, QI organizations and others in the development of a sustainable ANN Learning Community
• Co-develop standardized data tools, database and dashboards of key quality metrics for inpatient level 2 Small or Sick Newborn (SSN) care with CPAP
• Utilize a linked data system to drive a mentored QI collaborative focused on reduction of neonatal mortality among patients admitted to participating ANN inpatient neonatal units


Uganda 2026-01-30 9:04:39 2029-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bonny Kagaba
ID: UNCST-2025-R022730
 Transforming Futures: Women’s Social Entrepreneurship in Uganda in a Digital Age.
REFNo: SS4761ES

Specific Objectives 1. Explore digital tools  To examine how women social entrepreneurs use mobile money, social media, and e-commerce platforms to manage finances, reach customers, and scale their ventures. 2. Identify barriers to digital inclusion  To investigate challenges such as limited internet penetration, high electricity costs, low digital literacy, and persistent gendered norms that constrain women’s participation in digital entrepreneurship. 3. Assess policy and institutional implications  To evaluate the effectiveness of initiatives such as UWEP, GROW, and Standard Chartered’s Women in Tech program in supporting women’s digital entrepreneurship, and identify gaps in policy frameworks. 4. Contribute to theory and practice  To apply Dees’ (1998, 2001) principles of social entrepreneurship and digital inclusion indicators to analyse women’s entrepreneurial strategies, generating insights for academic scholarship, policy design, and practical interventions.
Uganda 2026-01-30 19:44:01 2029-01-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joshua Ainomugisha
ID: UNCST-2025-R019411
 Female Gender Stereotypes, Parental Influence and Female Students’ Engagement in Vocational Training in Nakivale Vocational Training Centre, Isingiro District, Uganda.
REFNo: SS4759ES

To examine the extent to which female gender stereotypes influence female students' engagement in vocational training in Nakivale Vocational Training Centre.
2. To assess the relationship between parental influence and female students' engagement in vocational training in Nakivale Vocational Training Centre
3. To assess the combined predictive power of female gender stereotypes and parental influence on female students' engagement in vocational training in Nakivale Vocational Training Centre.
4. To find out the mediating effect of parental influence on the relationship between female gender stereotypes and female students' engagement in vocational training in Nakivale Vocational Training Centre.
5. To establish the challenges faced by female students in engaging in vocational training in Nakivale Vocational Training Centre as a result of female gender stereo types and parental influence

 Uganda 2026-01-30 19:42:19 2029-01-30 Social Science and Humanities Non-Clinical Trial Degree Award
Elias Kumbakumba
ID: UNCST-2022-R011183
 Childhood Disability: Exploring the burden, community perceptions, caregiver and VHT perspectives, health system and school readiness in Southwestern Uganda
REFNo: HS6976ES

1.To explore community knowledge, beliefs, and stigma related to congenital and acquired childhood disabilities, and to document caregiver experiences, psychosocial burden, and care-seeking behaviors as told by VHTs
2.To catalogue the prevalence, types, and demographic distribution of childhood disabilities in Rubirizi district, South Western Uganda, using both community-level and education system data.
3.To assess the readiness of the health and school systems, and community health workers to support the early identification, referral, and intervention for children with disabilities
4.To develop and share digital stories capturing lived experiences of caregivers of children with disabilities, reflecting key study themes to inform communities, service providers, and policymakers.

 Uganda 2026-01-30 19:40:25 2029-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Barbara Acheng
ID: UNCST-2025-R022067
 INVESTIGATING DATA SHARING ASYMMETRIES AND DEVELOPING A MONITORING FRAMEWORK FOR ANTIMICROBIAL RESISTANCE DATA SHARING IN UGANDA
REFNo: HS6959ES

1. To identify the current AMR sharing practices across the One Health sectors in Uganda.
2. To determine the barriers and enablers to effective inter-sectoral AMR data sharing.
3. To develop a monitoring framework for inter-sectoral AMR data sharing.

 Uganda 2026-01-30 19:39:07 2029-01-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Suzanne  Kiwanuka N
ID: UNCST-2020-R014671
 Strategic Analytics for a Sustainable and Resilient Health Supply Chain in Uganda: An assessment of the financing landscape, fiscal space, interventions, subnational and last mile supply chain system performance
REFNo: HS7026ES

4. To assess the sub-national and last-mile supply chain system in Uganda, with emphasis on stock-outs, wastage, redistribution practices, coping mechanisms, and community health supply chain functionality. ,3. To analyze recent interventions to address key bottlenecks in Uganda’s health supply chain and develop actionable solutions to strengthen supply chain design, functionality and resilience.,2. To conduct a fiscal space analysis to identify feasible and innovative financing mechanisms that can strengthen, sustain, and improve the resilience of Uganda’s health supply chain.,1. To analyze Uganda’s health funding landscape and assess how recent disruptions have affected the supply chain for essential medicines and health supplies (EMHS).,To assess the current funding landscape, effect of funding disruptions, fiscal space, interventions and last mile supply chain system performance to generate strategic evidence that informs systemic reforms and strengthens the performance, sustainability, and resilience of Uganda’s health supply chain.,
 Uganda 2026-01-30 19:37:49 2029-01-30 Medical and Health Sciences Non-degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
 Evaluating the impact on 90-day survival of post-discharge follow-up strategies delivered to adult patients hospitalized with sepsis across a research network in sub-Saharan Africa [Call for Life – Sepsis (C4L-Sepsis)]
REFNo: HS6882ES

To compare baseline demographic and clinical characteristics between participants who were randomized and those who did not meet randomization criteria (screen failures),To evaluate participant quality of life at 28- and 90-days post discharge period within two study arms.,To evaluate the proportion of participants within the two study arms who require re-admission to hospital during the post-discharge period of 90 days,To evaluate proportion of participants within the two study arms who return for scheduled post discharge follow-up visits ,To evaluate the efficacy on 28-day mortality among participants hospitalized with sepsis randomized to receive one of two post discharge follow-up strategies – EDI versus EDI plus IVR tool,To evaluate the efficacy on 90-day post-discharge mortality among adult participants hospitalized with sepsis randomized to receive one of two post discharge follow-up strategies – EDI versus EDI plus IVR tool,III. To train clinical officers about vitamin D and its application in managing the co-morbidity illnesses under study. This involves training and mentoring of clinical officers so as to acquire knowledge about vitamin D especially in relation to its clinical effects and treatment of malaria, diabetes, HTN, UTIs, and post covid-19 syndrome. This will enable build enough human capacity and willingness to carry out more research about vitamin D.,To develop prototypes of the efficacy doses of vitamin D for each co- morbidity group. From objective II, the efficacy doses (values) of vitamin D will be recorded. Vitamin D prototypes containing different formulations for each co-morbidity illness will be developed. These will be in form of; solutions, powder and inhalers,To establish the efficacy of vitamin D to the co-morbidity illnesses. This involves giving different doses of vitamin D to study participants in each co- morbidity group in addition to the illness’ conventional drugs while monitoring for change using the monitors of change tests/investigations to ascertain these therapeutic effects of Vitamin D.,To develop prototypes of the efficacy doses of vitamin D for each co-morbidity group. ,To explore vitamin D’s therapeutic efficacy to the co-morbidity diseases (malaria, HTN, diabetes, UTIs and post covid-19 syndrome) under study,III. To train clinical officers about vitamin D and its application in managing the co-morbidity illnesses under study. ,II. To develop prototypes of the efficacy doses of vitamin D for each co-morbidity group,I. To establish the efficacy of vitamin D to the co-morbidity illnesses,To explore vitamin D’s therapeutic efficacy to the co-morbidity diseases (malaria, HTN, diabetes, UTIs and post covid-19 syndrome) under study. ,III. To train clinical officers about vitamin D and its application in managing the co-morbidity illnesses under study. This involves training and mentoring of clinical officers so as to acquire knowledge about vitamin D especially in relation to its clinical effects and treatment of malaria, diabetes, HTN, UTIs, and post covid-19 syndrome. This will enable build enough human capacity and willingness to carry out more research about vitamin D,II. To develop prototypes of the efficacy doses of vitamin D for each co-morbidity group. From objective II, the efficacy doses (values) of vitamin D will be recorded. Vitamin D prototypes containing different formulations for each co-morbidity illness will be developed. These will be in form of; solutions, powder and inhalers ,I. To establish the efficacy of vitamin D to the co-morbidity illnesses. This involves giving different doses of vitamin D to study participants in each co-morbidity group in addition to the illness’ conventional drugs while monitoring for change using the monitors of change tests/investigations to ascertain these therapeutic effects of Vitamin D.,To explore vitamin D’s therapeutic efficacy to the co-morbidity diseases (malaria, HTN, diabetes, UTIs and post covid-19 syndrome) under study. This will be achieved by clinical application of vitamin D, assessing and monitoring its effect in the treatment of the respective comorbidity illness as well as developing of different formulations of vitamin D that had effect in each co-morbidity group. ,
 Uganda 2026-01-30 19:36:32 2029-01-30 Medical and Health Sciences Clinical Trial Non-degree Award
Esther Nanfuka Kalule
ID:
CHALLENGING INTIMATE PARTNER VIOLENCE IN FORMAL AND INFORMAL RELATIONSHIPS THROUGH PROSOCIAL GAMING: REDUCING PREVALENCE AND RISK FACTORS, AND ENHANCING THE EXPERIENCES OF AFFECTED YOUNG PEOPLE IN UGANDA (INIFIRES)
REFNo: SS4748ES

Main objective
To examine the prevalence, risk factors and experiences of IPV among young people age 15-24 in formal and informal relationships to inform the development of a co-created game-based intervention to tackle IPV among young people in Uganda.

Specific objectives
1.To determine the prevalence of IPV among young people age 15-24 years in formal and informal relationships in conflict-affected and peaceful regions.
2.To explore young people’s aspirations and expectations for happy and healthy relationships with their future romantic partners.
3.To explore the anticipated and observed effects of IPV on victims and perpetrators in the different Ugandan contexts.
4.To generate data for co-creation of a prosocial gaming intervention for young people to address and prevent IPV and to encourage help-seeking for those affected.

 Uganda 2026-01-30 19:33:10 2029-01-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Niringiye
ID: UNCST-2025-R017755
 Contested Citizenship: The Case of Kinyarwanda-Speakers Astride the Congo–Uganda Border
REFNo: SS4749ES


I. Examine how colonial border-making disrupted indigenous land and kinship systems, creating fragmented identities and contested sovereignties.

ii. Analyse postcolonial citizenship laws and land policies in Uganda and the DRC that institutionalize exclusion and marginalization.


iii. Investigate informal survival strategies employed by borderland communities to negotiate land access and citizenship amid legal ambiguity and political exclusion.

iv. Interrogate historical narratives and collective memories and how they shape contemporary identity and conflict among Kinyarwanda speakers in the border region?

 Uganda 2026-01-30 19:29:06 2029-01-30 Social Science and Humanities Non-Clinical Trial Degree Award
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