Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
MARY MUGABEKAZI
ID: UNCST-2024-R002638
Prevalence and Risk Factors Associated with Recent and Long-Term HIV Infections Among Newly Identified HIV Positive Clients in Kyenjojo District, Western-Uganda
REFNo: HS6381ES

To find out the prevalence and risk factors associated with recent & long-term HIV infections among newly identified HIV positive clients in Kyenjojo District, Western-Uganda.,
Uganda 2025-09-09 13:48:40 2028-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Atuhaire Rosemary
ID: UNCST-2024-R003132
Parenting Styles, Students’ Connectedness and Academic Adjustment among Pre- Service Teachers in Universities of South Western Uganda
REFNo: SS3370ES

7. To evaluate the mediating role of student connectedness in the associations between parenting styles and academic adjustment among pre-service teachers in universities in south western Uganda.,6. To investigate the relationship between student connectedness and academic adjustment among pre-service teachers in universities in south western Uganda.,5. To explore the correlation between parenting styles and student connectedness among pre-service teachers in universities in south western Uganda.,4. To examine the relationship between parenting styles and academic adjustment among pre-service teachers in universities in south western Uganda.,3. To assess the levels of academic adjustment among pre-service teachers in universities in south western Uganda.,2. To identify prevalent parenting styles among pre-service teachers in universities in south western Uganda.,1. To investigate how academic adjustment varies across demographic variables among pre-service teachers in universities in south western Uganda.,To investigate the associations between parenting styles, students\' connectedness, and academic adjustment among pre-service teachers in the universities of south western Uganda.,
Uganda 2025-09-09 13:44:49 2028-09-09 Social Science and Humanities Non-Clinical Trial Degree Award
GRACE ANKUNDA
ID: UNCST-2025-R017443
TEACHER COMPETENCE, MOTIVATION AND ACTIVE LEARNING OF PRE-PRIMARY SCHOOL CHILDREN IN UGANDA: A CASE OF KABALE DISTRICT
REFNo: SS3854ES

1) To examine the influence of teacher competence on active learning among pre-primary school children in Kabale district. 2) To analyse the effects of teacher motivation on active learning among pre-primary school children in Kabale district. 3) To assess the influence of teacher competence on teacher motivation in pre-primary schools in Kabale District. 4) To investigate the mediating role of teacher motivation in the relationship between teacher competence and active learning among pre-primary school children in Kabale district.
Uganda 2025-09-09 13:42:02 2028-09-09 Social Science and Humanities Non-Clinical Trial Degree Award
MARGARET AANYU
ID: UNCST-2023-R003677
Adopting multidisciplinary approaches in genetic improvements, nutritional enhancements and climate change adaptation for improved production of Nile tilapia in Uganda
REFNo: A637ES

The main objective of the project is to breed Nile tilapia for improved growth and temperature resilience, and formulation of commercially competitive and environmentally safe fish feeds for sustainable production of Nile tilapia in Uganda. The specific objectives include to: 1. Study effects of elevated water temperature on the growth, survival and physiology of Nile tilapia strains from Ugandan lakes Victoria, Kyoga, Albert, and Edward 2. Select and breed Nile tilapia strains from Ugandan lakes Victoria, Albert, Edward for both improved growth and tolerance to elevated temperature. 3. Develop cost-effective and environmentally safe feeds for fast growing temperature-resilient Nile tilapia strains. 4. Popularising the fast growing Nile tilapia strain resilient to elevated water temperature and the allied feeding regimes.
Uganda 2025-09-09 13:39:52 2028-09-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
STRIVE 002: An International Observational Study of Adults with Acute Infection
REFNo: HS6420ES

The general aim of this observational study is to is to understand more about what happens when adults are hospitalised with acute infectious diseases.
• Characterise and compare the clinical course and natural history of acute infections of interest
• Determine the percentage who die or develop other adverse outcomes during or following hospitalisation
• Identify host and pathogen risk factors for poor outcomes.
Uganda 2025-09-09 13:38:25 2028-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AYESIGYE JUSTUS
ID: UNCST-2025-R020078
SUSTAINABILITY DISCLOSURE INTEGRITY: A PROPOSED GUIDANCE FRAMEWORK FOR THE MANUFACTURING SECTOR IN UGANDA
REFNo: SS4214ES

To assess the scope, quality, comparability, and regulatory alignment of sustainability disclosure practices among sampled Ugandan manufacturing firms in order to identify strengths, gaps, and priority improvement areas To explore the existing sustainability disclosure frameworks in the context of manufacturing sector in Uganda To examine the association between disclosure regime (mandatory vs. voluntary elements) and stakeholder-perceived trustworthiness of sustainability informationTo assess and evaluate existing research methodologies and propose the adoption of an appropriate methodology that addresses the research problem To ascertain the perceptions of sustainability disclosure integrity from professionals and regulators in the context of manufacturing organisations–fieldwork To recommend a proposed guidance framework for enhancing sustainability disclosure integrity in the Ugandan manufacturing sector To conclude the study by offering recommendations and identifying areas for future research
Uganda 2025-09-04 13:17:34 2028-09-04 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel  Obakiro Baker
ID: UNCST-2019-R000065
ASSESSMENT OF THE PHARMACEUTICAL SYSTEM CAPABILITIES AND CAPACITY TO MANUFACTURE, PROCURE AND DISTRIBUTE ESSENTIAL MEDICINES IN UGANDA (MaPDeM)
REFNo: HS5670ES

To explore the experiences and perceptions of communities on the utilization of pharmaceutical information systems regarding essential medicines,To evaluate the distribution networks and mechanisms for effective delivery of essential medicines to health facilities in Uganda. ,To assess the enablers and barriers for local pharmaceutical manufacturing of essential medicines in Uganda. ,To assess the pharmaceutical system capabilities and capacity to manufacture, procure and distribute essential medicines in Uganda. ,
Uganda 2025-09-04 12:54:38 2028-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tayebwa Bamwenda James
ID: UNCST-2021-R012825
SOCIAL SAFEGUARDS IMPLEMENTATION EFFECTIVENESS FOR HYDRO-POWER PROJECTS IN THE NILE BASIN: A CASE OF UGANDA.
REFNo: SS4172ES

1. To analyze the performance indicators of social safeguards for international frameworks on hydro-power projects, identifying implementation gaps at the national level.
2. To assess the implementation process of social safeguards of hydro-power projects in protecting communities, focusing on livelihood restoration, land use, and displacement.
3. To analyze the enabling and hindering factors affecting the implementation of social safeguards in hydro-power projects across the Nile Basin
4. To assess the community coping mechanisms with social safeguards and hydro-power projects in the Nile Basin

Uganda 2025-09-04 12:05:39 2028-09-04 Social Science and Humanities Non-Clinical Trial Degree Award
Ben Broomfield Stuart
ID: UNCST-2025-R017589
Understanding the evolutionary divergence and adaptation of Afrotropic Aedes (Stegomyia) zoonotic disease vectors using de-novo genome assemblies and comparative genomics
REFNo: NS1002ES

Objective 1- Generate de novo genomes for target Aedes (Stegomyia) species using freshly collected material

Objective 2- Reconstruct demographic history of Aedes mosquitos in African forests

Objective 3- Identify genomic introgression, if any, between closely related Aedes species

Objective 4- Identify genomic regions involved in adaptive divergence between closely related Aedes species

UK 2025-09-04 12:03:37 2028-09-04 Natural Sciences Non-Clinical Trial Degree Award
Emmanuel Kyasanku
ID: UNCST-2022-R009112
Seroepidemiology of dengue and other arboviruses and socio-demographic factors associated with seropositvity in Wakiso and Hoima Districts, Uganda.
REFNo: HS6326ES

1. To establish dengue and other arbovirus sero prevalence rates, by antibody detection assays and virus neutralization testing among residents of rural and urban communities, in a retrospective, longitudinal cohort study in Wakiso and Hoima Districts, Uganda, from 2018 through 2024. 2. To establish socio-demographic factors associated with seropositivity, among residents of rural and urban communities in Wakiso and Hoima Districts from 2018 through 2024. 3. To estimate anti-dengue and anti-arbovirus antibodies seroconversion rates among residents of rural and urban communities in Wakiso and Hoima Districts from 2018 through 2024.
Uganda 2025-09-04 11:45:58 2028-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joanitah  Nalunjogi
ID: UNCST-2023-R008356
Epidemiology of Household Energy use Burns in Selected Health Facilities in Uganda
REFNo: HS5879ES

1. To estimate the prevalence of household energy use burns in Jinja district, Uganda and factors associated.
2. To determine the relationship between the severity of burns and household energy sources used among patients managed at selected health facilities in Uganda.
3. To determine the factors associated with the eight-month physical, functional and mental outcomes of patients managed for household energy use burns in selected health facilities in Uganda.
4. To explore the experiences and perceptions of patients or caregivers on the causes, prevention and management of household energy use burns in Uganda

Uganda 2025-09-03 5:14:06 2028-09-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Chris  Opesen C
ID: UNCST-2023-R006913
Experiences of National Social Scientists in Outbreak Preparedness and Response in Uganda: Challenges and Opportunities for Participation"
REFNo: SS4003ES

1.3.1 General objective
The primary aim of this study is to understand the experiences of national social scientists in SSA and the challenges they have faced with integration during outbreak PPRR activities, with an aim to better integrating their expertise into future PPRR efforts and maximise the use of local human resources.
1.3.2 Specific Objectives
The study’s specific objectives are:
To identify and map the challenges and opportunities for national social scientists’ participation in PPRR, with a particular focus on their experiences in the recent Ebola, COVID-19, Anthrax, Marburg, Cholera, Malaria and Mpox responses.
To collaborate with national social scientists in co-creating evidence, including success stories, that advocates for their increased involvement in outbreak PPRR efforts.
To identify opportunities for providing actionable recommendations that enhance the integration of national social scientists into future outbreak PPRR activities, both within their country’s emergency response framework and internationally within the GOARN.
To contribute to the ongoing decolonisation of global health by amplifying national social scientists’ voices and co-developing strategies that empower social scientists in LMICs.
Uganda 2025-09-03 5:11:57 2028-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
Reducing short and long-term consequences of early stunted growth (MAGNUS-2).
REFNo: HS6274ES

To assess the associations between stunting and gut microbiota and function among 6-10-year-old previously stunted Ugandan children.,To assess the associations between stunting and growth, body composition, child development, haemoglobin, micronutrient status and organ size (liver, kidney, spleen) among 6-10-year-old previously stunted Ugandan children,To assess predictors of cardiometabolic risk markers among 6-10-year-old previously stunted Ugandan children,To assess the long-term effects of 3-months supplementation with large-quantity LNS among 1-5-year-old Ugandan stunted children on gut microbiota and function at age 6-10 years. ,To assess the long-term effects of 3-months supplementation with large-quantity LNS among 1-5-year-old Ugandan stunted children on growth, body composition, child development, haemoglobin, micronutrient status and organ size (liver, kidney, spleen) at age 6-10 years,To assess the association between stunting and cardiometabolic risk among 6-10-year-old Ugandan children,To assess the long term effects of 3-months supplementation with large-quantity LNS among 1-5-year old Ugandan stunted children on cardiometabolic risk markers at age 6-10 years.,To assess long-term effects of supplementation with large quantity LNS on child health,
Uganda 2025-09-03 5:10:27 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
Implementation of the International Guidelines for Skin-to-Skin in the First Hour After Birth: Expansion and Sustainability for a Ugandan Hospital in Masaka
REFNo: HS6282ES

To assess the impact of training and support regarding breastfeeding latch and infant feeding practices at around 6 weeks postpartum.,To assess the impact of a rapid change intervention with the staff on the the perineal tears and episiotomies during vaginal birth,To explore and understand the experience of the mothers who experience skin-to-skin contact after birth and their experience of breastfeeding in the postpartum period,To explore and understand the experience of the staff regarding the barriers and enablers to implementing breastfeeding assessment before discharge,To assess the breastfeeding latch and response to breast milk odour of the newborn before discharge with routine care in the first hour and after implementation of immediate, continuous SSC in the hospital,To explore and understand the experience of the staff regarding the barriers and enablers to implementing and sustaining the international guideline for skin-to-skin care in the first hour after birth, and the new recommendation of 90 minutes, and to identify and implement solutions,To understand the newborn\'s experience after birth, the practice change using video ethnography will be increased to 90 minutes and compared with current care practices following the initial introduction of immediate skin-to-skin contact.,To assess the long-term sustainability of uninterrupted skin-to-skin contact (SSC) in the first hour after birth and within 90 minutes after both vaginal and cesarean section. ,To evaluate the implementation, sustainability, and impact of uninterrupted skin-to-skin contact (SSC) in the first hour after birth and increase it for at least 90 minutes at Masaka Regional Referral Hospital, Uganda, focusing on newborn outcomes, maternal experiences, perineal outcomes, healthcare staff perspectives, and its influence on breastfeeding practices,
Uganda 2025-09-03 5:08:35 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jamon Van Den Hoek
ID: UNCST-2023-R006549
Gauging Agricultural Land-Use Decisions and Boundaries in Refugee Settlements in Uganda
REFNo: SS4159ES

This project seeks to 1) collect information on factors that influence agricultural land use decisions in refugee settlements in Uganda, and 2) estimate the boundary (the outermost extent) of agricultural lands accessed or managed by refugees. The first objective provides information on factors associated with cropland dynamics in refugee settlement. The second objective allows us to associate satellite-mapped cropland dynamics to specific refugee settlements.

This project follows the UNCST-approved research project, "Multi-sensor Mapping of Refugee Agricultural Land-Cover/Land-Use Change Hotspots in Uganda" (RefNo: A414ES), which sought to collect information on crop type and condition at refugee settlements for further satellite image analysis.
USA 2025-09-03 5:07:37 2028-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
George Kasule
ID: UNCST-2025-R020040
HOUSEHOLD DEBT MANAGEMENT IN UGANDA
REFNo: SS4141ES

1. To investigate the relationship between number of the loan and household debt management in Uganda.
2. To examine the moderating effect of purpose of the loan in the relationship between number of loans and household debt management in Uganda.
3. To assess the relationship between financial knowledge and household debt management in Uganda.
4. To investigate the relationship between institutional innovative financial technologies and household debt management in Uganda.
5. To assess the relationship between social networks and household debt management in Uganda
6. To examine the relationship between remittances and household debt management in Uganda.

Uganda 2025-09-03 5:06:34 2028-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Betty Mwesigwa
ID: UNCST-2020-R014667
CASCADE C-3001-A: Comparison of Clinic-based versus Clinic- plus Community Outreach-based Strategy to Increase Uptake of Cervical Cancer Screening via HPV Self-Collection among Women Living with HIV: a Cluster Randomized Trial.
REFNo: HS6333ES

To compare cervical cancer monthly screening rates in screen-eligible women living with HIV (WLWH) between the two screening models: standard-of-care for cervical cancer screening through static clinics only (Model 1) versus HPV self-collection through both static clinics and a community-based screening strategy by facility link facilitators (FLFs) (Model 2). Standard-of-care for Model 1 is defined as HPV self-collection when available or Visual Inspection with Acetic Acid (VIA) when HPV-based screening is not available
Uganda 2025-09-03 5:05:44 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel  Emoru Reagan
ID: UNCST-2025-R020048
Safeguarding Public Health in the Face of Climate Change: Evaluating Uganda's National Policies and Catalyzing Stakeholder Action
REFNo: HS6332ES

1. To conduct a comprehensive review and analysis of Uganda’s national climate change policies, with a particular emphasis on understanding what policies are available and identifying and assessing the inclusion of health-related impacts, risks, and adaptation/mitigation measures.
2. To evaluate the mechanisms and efforts undertaken by the government and development partners to disseminate and raise awareness about these national climate change policies among relevant stakeholders.
3. To identify gaps and provide recommendations for strengthening the integration of health considerations in national climate change policies, as well as improving the dissemination and awareness-raising efforts among key stakeholders.

Uganda 2025-09-03 5:03:32 2028-09-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Cardiovascular risk factor profiles and outcomes in rural Uganda: The Bugoye Hypertension Improvement Project (B-HIP)
REFNo: HS6350ES

To evaluate the dietary intake and nutritional habits of adult patients visiting the BHIP clinic. To determine incidence of sustained blood pressure control among persons with hypertension enrolled in BHIP. To assess the costs of hypertension care in a Level III healthcare center in rural Uganda. ,1. To assess the baseline (at time of enrollment to BHIP) prevalence of various cardiovascular risk factors (obesity, dyslipidemia, and diabetes mellitus) in adults visiting the Bugoye Hypertension Improvement Project.,
Uganda 2025-09-03 4:49:54 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Slyvia  Aarakit Manjeri
ID: UNCST-2025-R016896
GREEN ENERGY FOR WOMEN AND YOUTH RESILIENCE IN UGANDA: BRIDGING THE SKILLS GAP THROUGH TECHNICAL AND VOCATIONAL EDUCATION AND TRAINING-TVET
REFNo: SS4196ES

Objectives
Theme 1: Mapping and Readiness
(i) To map Uganda’s clean energy sub-sector to identify knowledge, technical, and business skill gaps among women and youth entrepreneurs.
(ii) To assess the institutional readiness and capacity of TVETs to deliver inclusive, industry-relevant green energy and clean cooking training.
Theme 2: Curriculum and training
(iii) To co-create a green energy and clean cooking training curriculum for TVET institutions, and strengthen their technical capacity to deliver hands-on, industry-relevant training.
(iv) To enhance the technical and entrepreneurial skills of women and youth to produce/innovate and distribute green and clean cooking solutions in their communities.
Theme 3: Scale-up and Policy Influence
(v) To assess the contribution of TVET-based green energy and clean cooking training programs to green skills development, inclusive participation and resilience of women and youth entrepreneurs.
(vi) To promote public awareness and policy advocacy through transdisciplinarity in knowledge co-creation and dissemination among academia, TVET institutions, communities, policymakers, and private sector actors.

Uganda 2025-09-03 4:47:32 2028-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
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