Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Grace Nalukwago Kakoola
ID: UNCST-2025-R022885
 IMPLEMENTATION OF THE NON-MOTORIZED TRANSPORT PILOT CORRIDOR AND ITS EFFECTS ON ACTIVE MOBILITY IN KAMPALA UGANDA.
REFNo: HS7552ES

I. To explore the acceptability, inclusivity, and perceived barriers influencing the intended use of Kampala’s NMT pilot corridor. II. To examine the effect of the NMT pilot corridor on overall walking and cycling experiences in comparison to a motorized road. III. To compare walking-related physical activity levels between adults working along the NMT pilot corridor and those working along a motorized road in Kampala. IV. To examine the implementation of the NMT pilot corridor by examining the strategies adopted, and their outcomes over time during the post-construction phase (2021-2026).
Uganda 2026-07-16 19:58:26 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
PRISCILLA NASOLO
ID: UNCST-2025-R021017
 MANAGEMENT PRACTICES AND PERFORMANCE IN UGANDA REVENUE AUTHORITY AND UGANDA BROADCASTING CORPORATIONS IN UGANDA
REFNo: SS5228ES

1. To assess the effect of internal audit functions on the performance of URA and UBC in Uganda.
2. To evaluate the influence of corporate governance mechanisms on the performance of URA and UBC in Uganda.
3. To assess the extent to which strategic plan compliance affects the performance of URA and UBC in Uganda.
4. To determine the effect of capacity-building initiatives on the performance of URA and UBC in Uganda.
5. To examine the moderating effect of organizational culture on the relationship between selected management practices and the performance of URA and UBC in Uganda.

 Uganda 2026-07-16 19:56:25 2029-07-16 Social Science and Humanities Non-Clinical Trial Degree Award
Peter Waitt
ID: UNCST-2023-R007926
 Developing Educational Resources Using a Participatory Model for Refugee Mothers Using Maternity Services in West Nile District: CLEAR � Clear Language and Engaging Resources
REFNo: HS8007ES

To support refugee communities in Northern Uganda to develop resources to communicate effectively, in languages which their communities understand to reduce the risk of post operative sepsis. We aim to co-create materials including simple written material, infographics, flip-charts and short videos.
 UK 2026-07-16 19:55:13 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Baker Ssekitto
ID: UNCST-2026-R025418
 REGENERATIVE BUSINESS MODELS AS PREDICTORS OF INCLUSIVE DIGITAL SERVICE DELIVERY OUTCOMES IN RURAL WEST NILE, UGANDA: A MIXED METHODS STUDY
REFNo: SS5272ES

i. To explore the contextual requirements of a Regenerative Business Model in rural West Nile.
ii. To design a Regenerative Business Model artifact that integrates the identified dimensional requirements through stakeholder-validated Design Science Research workshops.
iii. To evaluate the effect of Regenerative Business Model dimensions on inclusive digital service delivery outcomes in rural West Nile, Uganda.
iv. To examine the moderating role of Community Engagement and Ownership on the dimensional relationships between RBM aligned practices and inclusive digital service delivery in rural West Nile, Uganda

 Uganda 2026-07-16 19:54:05 2029-07-16 Social Science and Humanities Non-Clinical Trial Degree Award
ONESMUS BYAMUKAMA
ID: UNCST-2021-R013826
 Association Between Pre-eclampsia/Eclampsia and Chronic Kidney Disease at 6 Months Postpartum Among Women in Southwestern Uganda
REFNo: HS7902ES

General Objective: To determine the incidence and risk factors of chronic kidney disease among women at 6 six months postpartum in southwestern Uganda, and to explore knowledge and perceptions of long-term renal health risks among women and healthcare providers Specific Objectives Primary Objectives 1.To determine the incidence and risk factors of chronic kidney disease among women at six months postpartum in southwestern Uganda. 2.To explore the knowledge and perceptions of postpartum women and healthcare providers regarding long-term renal health risks associated with pre-eclampsia/eclampsia. Secondary Objectives 1.To determine the proportion and factors associated with multi-organ dysfunction among pregnant women in southwestern Uganda. 2.To explore genetic polymorphisms potentially associated with distinct clinical phenotypes of pre-eclampsia among women in southwestern Uganda
Uganda 2026-07-16 19:52:20 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Adapting a Transitional HIV Treatment Support Model for Persons Leaving Incarceration in Uganda
REFNo: SS5343ES

To identify key features of an evidence-based transitional HIV treatment support model requiring adaptation for implementation success in rural Uganda.
 Uganda 2026-07-16 19:50:10 2029-07-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Felix Okello
ID: UNCST-2025-R021079
 COMMUNITY-LED WATER, SANITATION, AND HYGIENE INTERVENTIONS TO PREVENT SCHISTOSOMIASIS: AN ANTHROPOLOGICAL PERSPECTIVE OF LAKE COMMUNITIES IN WESTERN UGANDA
REFNo: SS5342ES

The study aims to apply an anthropological lens to analyze how community-led water, sanitation, and hygiene (WASH) interventions are conceived, negotiated, implemented, and experienced in schistosomiasis-endemic lake communities in western Uganda, and how these processes shape water-contact behaviours, WASH practices, and patterns of vulnerability to schistosomiasis.

The specific objectives
The following objectives shall guide the study:
1. To analyze how socio-cultural beliefs, local knowledge systems, and structural inequalities in lake communities of Kagadi District, western Uganda, shape everyday water contact behaviors, sanitation practices, and participation in community-led WASH interventions for schistosomiasis prevention.
2. To critically examine the processes, power dynamics, and outcomes of engaging citizen scientists and local communities in co-designing WASH interventions, and how these co-created interventions reflect and negotiate local values, norms, and lived realities.
3. To interrogate the cultural logics, symbolic meanings, and gendered social relations that influence the acceptance, rejection, and everyday use of endod-based soap as a community-led strategy for schistosomiasis prevention.
4. To conduct a qualitative evaluation of how community-led WASH approaches reconfigure local power relations, social organization, and collective action, and how these transformations affect WASH coverage, utilization, and sustainability in schistosomiasis-endemic lake communities, Kagadi District, western Uganda.

 Uganda 2026-07-16 19:47:07 2029-07-16 Social Science and Humanities Non-Clinical Trial Degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
 Comparison of bacteria isolated from the blood and gastrointestinal tract of patients with cancer and from their immediate hospital environment at the Uganda Cancer Institute (CompBac Study)
REFNo: HS7834ES

1. To determine the microbiological characteristics of the bacteria causing bacteremia, and colonizing the gastrointestinal tract of patients with at the Uganda Cancer Institute (UCI). 2. To determine the microbiological characteristics of the bacteria isolated from the immediate hospital environment of patients with cancer at the UCI. 3. To determine the phylogenetic characteristics of the bacteria causing bacteremia, colonizing the gastrointestinal tract and the immediate hospital environment of cancer patients at the UCI. 4. To determine the similarities or differences between the bacteria isolated above to previously isolated bacteria from cancer patients with bacteremia and from their immediate hospital environment at the UCI.
 Uganda 2026-07-16 19:43:56 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nakayiki Lilian Nyanzi
ID: UNCST-2025-R019152
 Validation of a region-specific Food Frequency Questionnaire for assessing habitual Dietary Intake and Indigenous Fruit and Vegetable consumption among Ugandan adults
REFNo: HS7771ES

To validate a region-specific Indigenous Fruit and Vegetable-Food Frequency Questionnaire (IFV-FFQ) as a tool for assessing habitual dietary intake, with a focus on Indigenous Fruits and Vegetables consumption, among Ugandan adults (>18 years).

 Uganda 2026-07-16 19:41:34 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Ivan Segawa
ID: UNCST-2021-R012795
 InstaGirls: On-Demand HIV Self?Testing, PrEP, and PEP Delivery for Online Sex Workers in Uganda
REFNo: HS7891ES

1. Assess the feasibility and acceptability of the InstaGirls on-demand, mobile-enabled courier delivery model for HIV prevention among online sex workers in Uganda. 2. Explore online sex workers’ perceptions, experiences, and perceived barriers and facilitators to using the InstaGirls model. 3. Estimate the cost of implementing the InstaGirls delivery model for HIV prevention in Uganda.
Uganda 2026-07-16 19:39:16 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Nabacwa Ssonko
ID: UNCST-2023-R007407
 ASSESMENT OF MINISTRIES, DEPARTMENTS, AND AGENCIES (MDAs) PERFORMANCE ON CARE-RELATED ACTIONS IN UGANDA USING THE NATIONAL CARE POLICY SCORE CARD
REFNo: SS5483ES

Interrogate drivers of change or stagnation,Identify care policy influencing opportunities,Analyse Ministries, Departments and Agencies performance using the national care policy scorecard,Assess the performance of Ministries, Departments, and Agencies (MDAs) in Uganda in implementing care-related policies, investments, and interventions using the National Care Policy Scorecard,
 Uganda 2026-07-16 19:36:40 2029-07-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Milly Kwagala
ID: UNCST-2025-R020368
 INNOVATIVE FINANCING MODELS AND BUSINESS FINANCIAL SUSTAINABILITY PRACTICES AMONG WOMEN-LED ENTERPRISES: A CASE STUDY OF MUKONO DISTRICT
REFNo: SS5426ES

4.3. General Objective To examine how innovative financing models and related support mechanisms influence the business financial sustainability of women-led enterprises in Mukono District, and to generate evidence-based recommendations for enhancing their long-term growth and resilience. 4.4 Specific Objectives 1) To determine how access to different financing models (traditional microfinance, blended finance, digital savings platforms, and Personality?Based Credit Screening) is associated with key indicators of business financial sustainability (profit retention, employment creation, and asset accumulation) of women-led enterprises in Mukono District. 2) To assess the extent to which participation in training and capacity-building programmes, levels of financial and digital literacy, and involvement in SACCOs/community savings groups predict business financial sustainability among women-led enterprises in Mukono District. 3) To evaluate how engagement with policy support systems (government, NGO, and donor programmes) and the roles of key stakeholders (microfinance institutions, community organizations, and business associations) contribute to business financial sustainability among women-led enterprises in Mukono District.
Uganda 2026-07-16 19:34:53 2029-07-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssinabulya
ID: UNCST-2021-R004352
 An mHealth implementation strategy to address the syndemic of mental illness, hypertension, and HIV in Uganda. Clinical Trial: Syndemic Adapted Medly Uganda (SAMU)
REFNo: HS7936ES

To evaluate the factors impacting sustained engagement in the adapted Medly Uganda,To assess the effectiveness of the Syndemic-Adapted Medly Uganda (SAMU) to improve mental health care cascade metrics. ,
 Uganda 2026-07-16 19:31:27 2029-07-16 Medical and Health Sciences Clinical Trial Non-degree Award
LYDIA NAKIGANDA
ID: UNCST-2025-R016917
 FEASIBILITY AND ACCEPTABILITY OF A PEER-DELIVERED HOME-BASED PrEP MODEL (HB-PREP) FOR FEMALE SEX WORKERS IN RURAL UGANDA
REFNo: HS7906ES

1. To adapt and co-develop a peer-delivered, home-based PrEP care model for female sex workers in rural Uganda 2. Conduct a pilot RCT to evaluate the acceptability and feasibility of the HB-PrEP care model for FSW in Uganda. 3. Qualitatively examine participants’ and interventionists’ experiences with the care model and identify facilitators and barriers to its implementation
 Uganda 2026-07-16 19:28:09 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Musa Sekikubo
ID: UNCST-2021-R014010
 A phase 3, randomized, placebo-controlled, double-blinded trial to evaluate the safety, tolerability, and immunogenicity of a multivalent Group B Streptococcus vaccine in healthy pregnant women and their infants.
REFNo: HS8122ES

To evaluate the aggregate predicted VE combining all 6 serotypes in GBS6 to provide protection from invasive GBS EOD based on serotype-specific anti-CPS IgG concentrations measured in infants at birth,To evaluate the aggregate predicted VE combining all 6 serotypes in GBS6 to provide protection from invasive GBS LOD based on serotype-specific anti-CPS IgG concentrations measured in infants at birth.,To assess the ability of GBS6 to induce anti-CPS IgG antibody levels predicted to provide protection from invasive GBS early-onset disease (EOD) caused by the 6 individual vaccine serotypes (Ia, Ib, II III, IV, and V) in infants when GBS6 is administered to healthy pregnant women.,To assess the ability of GBS6 to induce anti-CPS IgG antibody levels predicted to provide protection from invasive GBS late-onset disease (LOD) caused by the 6 individual vaccine serotypes (Ia, Ib, II III, IV, and V) in infants when GBS6 is administered to healthy pregnant women.,To assess the safety of maternal immunization in infant participants born to pregnant women who were vaccinated with GBS6 during pregnancy.,To describe the safety and tolerability of GBS6 in maternal participants,
 Uganda 2026-07-16 19:21:43 2029-07-16 Medical and Health Sciences Clinical Trial Non-degree Award
Semanda Davis
ID: UNCST-2026-R024893
 Management practices and infrastructure development of secondary schools in Uganda. A case of selected Adventist secondary schools in central region .
REFNo: SS5448ES

General Objective To examine the relationship between Management practices and infrastructure development in Adventist Secondary Schools in the Central Region of Uganda. Specific Objective i) To determine the relationship between Planning and infrastructure Development of SDA Secondary Schools in the central region of Uganda. ii) To assess the relationship between Coordination and infrastructure Development of secondary schools in the Central Region of Uganda. iii) To explore the relationship between monitoring and evaluation on the infrastructure Development of SDA Secondary Schools in Central Region of Uganda. iv) To Analyze the Moderating effect of SDA Church Policy on the infrastructure Development of SDA Secondary Schools in Central Region of Uganda.
Uganda 2026-07-16 19:14:14 2029-07-16 Social Science and Humanities Non-Clinical Trial Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 Evaluation of MiniDock MTB for Decentralized Molecular Testing During Community-Based Active TB Case-Finding in Uganda
REFNo: HS8104ES

To estimate the incremental cost per TB case successfully initiated on treatment and the incremental cost-effectiveness of integrating MiniDock MTB� into community-based TB screening, compared with the standard of care, from a health system perspective.,To assess the feasibility, acceptability, and adoption of integrating MiniDock MTB� into community-based active TB case-finding from the perspectives of (a) participants undergoing testing and (b) healthcare providers implementing the intervention.,To determine whether integrating MiniDock MTB� near point-of-care molecular testing into community-based TB screening reduces the time from initial screening contact to TB treatment initiation, compared with the standard of care (centralized GeneXpert testing).,
 Uganda 2026-07-16 17:26:06 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JIMMY ADOKO
ID: UNCST-2025-R022752
 RETENTION IN CARE AND ASSOCIATED FACTORS AMONG ADOLESCENTS RECEIVING ANTE-RETROVIRAL THERAPY (ART) IN SELECTED HEALTH FACILITIES IN ADJUMANI DISTRICT, UGANDA
REFNo: HS7420ES

1. To Identify socio-demographic factors associated with retention in care among adolescents on ART.
2. To Identify adolescent factors associated with retention in ART.
3. To Identify the community factors associated with adolescent retention on ART.
4. To Identify the health systems factors associated with retention in HIV care for adolescents on ART.
 Uganda 2026-07-16 15:36:28 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Makanika Vincent B
ID:
QUALITY OF SEXUAL HEALTHCARE AMONG PATIENTS WITH CHRONIC NON-COMMUNICABLE DISEASES IN RURAL WESTERN UGANDA: The Role of Sexual Emotional Competence in Patient Expectations, Satisfaction, and utilization of Sexual Healthcare.
REFNo: HS7903ES

General Objective
To assess how sexual emotional competence influences patient expectations, satisfaction, and utilization of sexual healthcare services.

Specific Objectives
1. To assess the levels and patterns of sexual emotional competence among patients with chronic non-communicable diseases in rural western Uganda.
2. To examine patients’ expectations regarding sexual healthcare services in rural western Uganda.
3. To determine patients’ levels of satisfaction with sexual healthcare services and perceived quality of sexual healthcare.
4. To examine the relationship between sexual emotional competence and patient expectations, satisfaction, and utilization of sexual healthcare services.
5. To assess whether patient expectations and satisfaction mediate the relationship between sexual emotional competence and utilization of sexual healthcare services.
6. To examine the influence of personal, clinical, and care-related characteristics on the relationships between sexual emotional competence, patient satisfaction, and utilization of sexual healthcare services.

 Uganda 2026-07-16 15:05:17 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Dumba Simon
ID: UNCST-2025-R019366
 DIGITAL PLATFORMS’ INFLUENCE ON ENGLISH LANGUAGE TEACHER TRAINEES’ BIOGRAPHIES AND LINGUISTIC REPERTOIRES AT KYAMBOGO UNIVERSITY, UGANDA
REFNo: SS5256ES

Investigate how English language teacher trainees interact with their peers and mentors on digital platforms, focusing on the forms, frequency, and purpose of these interactions. 2. Identify specific ways in which digital platforms contribute to the development of English teacher trainees’ language biographies and linguistic repertoires through their academic and social engagements. 3. Assess the patterns of participation and types of engagement English language teacher trainees exhibit in online communities related to English language teaching. 4.Examine how regular engagement with digital platforms contributes to changes in teacher trainees’ linguistic identities and informs their evolving pedagogical approaches.
 Uganda 2026-07-14 9:58:47 2029-07-14 Social Science and Humanities Non-Clinical Trial Degree Award
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