Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Lawrence Opio
ID: UNCST-2026-R025589
COUNSELLING INTERVENTIONS AND PASTORAL SUPPORT ON LEARNERS� BEHAVIOUR MODIFICATION IN CATHOLIC-FOUNDED PUBLIC SECONDARY SCHOOLS OF LANGO SUB-REGION, NORTHERN UGANDA
REFNo: SS5651ES

i. To assess the influence of Cognitive Behaviour Therapy (CBT) on Learners’ Behaviour Modification in Catholic-founded public secondary schools of Lango sub-region. ii. To assess the influence of Social Skills Training (SST) on Learners’ Behaviour Modification in Catholic-founded public secondary schools in Lango sub-region. iii. To examine the influence of Motivational Interviewing (MI) on Learners’ Behaviour Modification in Catholic-founded public secondary schools of Lango sub-region. iv. To assess the influence of Restorative Practices (RP) on Learners’ Behaviour Modification in Catholic-founded public secondary schools of Lango sub-region. v. To examine the influence of Pastoral Support (PS) on Learners’ Behaviour Modification in Catholic-founded public secondary schools of Lango sub-region.
Uganda 2026-09-04 14:31:52 2029-09-04 Social Science and Humanities Non-Clinical Trial Degree Award
Ganafa Sumani
ID: UNCST-2026-R023930
Risk Perception, Construction and Management among Commercial (Boda-Boda) riders in Greater Kampala Metropolitan Area (GKMA).
REFNo: SS5911ES

General objective The general objective is to examine risk perception, construction, and management among boda-boda riders in GKMA. Specific objectives 1. To explore how boda-boda riders in GKMA perceive risks in their work setting. 2. To analyze how risks are socially constructed among boda-boda riders in GKMA. 3. To examine boda-boda riders’ risk management strategies in GKMA. 4. To examine the dynamics of occupational risk among commercial boda-boda riders in Greater Kampala Metropolitan Area.
Uganda 2026-09-01 14:03:26 2029-09-01 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Clinical Performance Evaluation of the Urine HIV-1/2 Diagnostic Kit for Detection of HIV-1/2 Antibodies in Urine in Uganda.
REFNo: HS8557ES

To assess operational characteristics and ease of use, especially in resource-limited settings.,To compare the sensitivity and specificity of urine RDTs to blood-based tests, ensuring they meet WHO prequalification criteria.,
Uganda 2026-09-01 13:49:35 2029-09-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
George Ndagga
ID:
Assessment of the Laboratory Capacity to Handle Infectious Disease Outbreaks in Selected Border Districts of Uganda
REFNo: HS8550ES

To explore the facilitators that have enhanced the border districts laboratory\'s ability to effectively detect, confirm, and respond to infectious disease outbreaks,To explore the major challenges that limit the border districts laboratory\'s ability to effectively detect, confirm, and respond to infectious disease outbreaks. ,To assess the capacity of laboratories in the border districts of Kasese and Kyotera to effectively detect, confirm, and respond to infectious disease outbreaks.,To assess the capacity of border district laboratories to handle future infectious disease outbreaks.,
Uganda 2026-09-01 13:14:45 2029-09-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Nabuufu N/A
ID: UNCST-2026-R024133
MOTHER CENTRED ANTENATAL HEALTH EDUCATION INTERVENTION FOR RURAL PREGNANT MOTHERS IN BUIKWE DISTRICT.
REFNo: SS5909ES

Main objective To develop and test the effectiveness of a mother-centred antenatal education module for pregnant mothers in a rural community in improving maternal and child health care practices. Research objectives 1) To explore the learning needs of pregnant mothers attending antenatal health education in rural community hospitals based on their experiences and perceptions. 2) To co-develop a mother-centred antenatal health education module tailored to learning needs and contexts of rural mothers. 3) To implement a mother-centred antenatal education module as an intervention tailored to learning needs and the local context of mothers in a rural community. 4) Assess the effectiveness of a mother-centred antenatal health education intervention module in improving maternal and child health practices of mothers in a rural community
2026-09-01 13:07:59 2029-09-01 Social Science and Humanities Non-Clinical Trial Degree Award
Barbra Babweteera
ID: UNCST-2026-R026121
Connecting Indigenous Stewardship Across Continents: Identifying Pathways for Equitable Fisheries Governance in Canada and Uganda
REFNo: SS5727ES

To document and analyze Indigenous governance approaches, cultural connections to fish and water, and fishing practices in Ugandan and Canadian inland fisheries, while building cross-regional a liances that facilitate mutual learning and generate comparative insights grounded in IK and community priorities. 2. To co-create shared visions of equitable fisheries governance that center IK, emphasizing themes of climate resilient food systems, youth engagement, and inclusive representation in National and Global fisheries policies. 3. To develop a community-driven research agenda that identifies knowledge gaps and provides a set of actionable recommendations for researchers, policymakers, and communities to strengthen equity and resilience in fisheries governance and to contribute to law reform.
Uganda 2026-09-01 12:55:54 2029-09-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Albert Nuwagira
ID: UNCST-2025-R022942
Bridging food and gut microbiome: Exploring the role of food microbes in the modulation of the gut microbiome and in the improvement of human health
REFNo: A791ES

Overall objective: To investigate the influence of traditional fermented foods on the gut microbiome of rural Ugandan populations using shotgun metagenomic sequencing. Specific objectives: 1. To characterise the microbial communities present in traditional fermented food samples through shotgun metagenomic sequencing; 2. To analyse gut microbiome composition and functional potential in faecal samples from individuals in rural Uganda; and 3. To investigate the relationship between traditional fermented food consumption and the gut microbiome amongst low and high consumers
Uganda 2026-09-01 12:51:05 2029-09-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
Ellon Kebirungi
ID:
Church and Holistic Development of Children. A case of West Ankole Diocese
REFNo: SS2165ES

3) To establish a strategy for the holistic development of children in West Ankole Diocese.,2) To examine the challenges, the church has in the holistic development of children,1) To assess the existing Church programmes for the holistic development of children,
Uganda 2026-09-01 12:43:23 2029-09-01 Social Science and Humanities Non-Clinical Trial Degree Award
Edith Wakida K
ID: UNCST-2019-R001225
Building Implementation Science Research Capacity in Uganda: A Qualitative Evaluation of the BImS-NCDs Training Program
REFNo: HS7657ES

1. Examine participant experiences and perceptions of the major components of the BImS-NCDs program, including the implementation science training program, research capacity short courses, mentored research activities, and the Alcohol-AD/ADRD administrative supplement.
2. Identify contextual factors influencing program implementation, including institutional and environmental conditions that facilitated or constrained participation and research activities.
3. Explore perceived training outcomes resulting from participation in the program, such as changes in research knowledge, skills, confidence, research engagement, and professional development, encompassing both primary individual-level outcomes and secondary institutional and mentorship outcomes.
4. Assess perceived contributions of the program to strengthening institutional research capacity, including mentorship networks, research collaborations, research productivity related to non-communicable diseases, and sustainability of research training initiatives.
Uganda 2026-09-01 12:20:48 2029-09-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizabeth Kemigisha Kemigisha
ID:
Addressing the Nexus: Sexual and Reproductive Health and Mental Health of Young Refugee and Migrant Women in Ecuador and Uganda
REFNo: HS8292ES

- To explore health-seeking behaviors and identify key sexual and reproductive health (SRH) and mental health (MH) challenges among YWRMs. - To map and document existing local programs, services, and initiatives addressing SRH and MH for YWRM, including gaps, coverage, and opportunities for integration or strengthening services - To co-create an evidence-based and context-adapted intervention with key stakeholders to address the nexus between SRH and MH challenges among YWRM in Nakivale Refugee settlement and Ecuador.
Uganda 2026-08-28 9:43:45 2029-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Denis Kayiwa
ID: UNCST-2026-R024516
UTILISATION OF DIFFERENTIATED SICKLE CELL DISEASE SERVICES AND HEALTH RELATED QUALITY OF LIFE AMONG ADOLESCENTS ATTENDING MULAGO HOSPITAL SICKLE CELL CLINIC: RANDOMISED CONTROLLED TRIAL
REFNo: HS8528ES

1. To examine the effect of uptake of differentiated sickle cell disease care service (DSCDS) on HRQoL among adolescents attending Mulago National Referral Hospital sickle cell clinic in Uganda.

2. To examine the relationship between utilization of differentiated sickle cell disease care services (DSCDS) and HRQoLamong adolescents attending Mulago National Referral Hospital sickle cell clinic in Uganda
3. To examine the effect of psychosocial support on HRQoL among adolescents attending Mulago National Referral Hospital sickle cell clinic in Uganda
4. To evaluate the moderating effect of patient factors on the relationship between utilization of differentiated sickle cell disease care service and HRQoL among adolescents attending Mulago National Referral Hospital sickle cell clinic in Uganda
Uganda 2026-08-28 9:40:45 2029-08-28 Medical and Health Sciences Non-Clinical Trial Degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
SCHEMA-Uganda: Strengthening Community Health and Epidemic Management in Uganda
REFNo: HS8495ES

To explore how stakeholder engagement, supported by participatory modeling, facilitates evidence-informed decision-making and strengthens policy coalitions for community health systems in Uganda,To explore how Uganda�s community health system can be strengthened to optimize resource allocation, improve outbreak preparedness, and enhance delivery of routine and emergency services ,To strengthen the policy coalition and enhance the capacity for planning and implementation of Uganda\'s National Community Health Strategy,
Uganda 2026-08-28 9:30:19 2029-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon  Kasasa
ID: UNCST-2021-R012861
Spatial Clustering and Distribution of Tuberculosis in Uganda: Identifying High-Risk Areas and Environmental Drivers for Targeted Public Health Action
REFNo: HS8538ES

To describe the associations between TB notification rates and selected environmental, socio-demographic, and healthcare-system factors using spatial regression models,To establish temporal trends in TB notification rates over the study period using time-series analysis and SaTScan space-time scan statistics.,To identify statistically significant TB spatial clusters (hotspots and cold spots) and map and characterize the geographic extent and magnitude of high-risk areas,To map and characterize the spatial distribution of TB case notifications across Ugandan districts from 2021 to 2025.,To analyze the spatial clustering and temporal distribution of tuberculosis case notifications across all 146 districts of Uganda from 2021 to 2025, identify high-risk areas, characterize associated environmental and socio-demographic determinants, and generate actionable evidence to guide targeted TB public health interventions.,
Uganda 2026-08-28 9:01:26 2029-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dan Kajungu
ID: UNCST-2019-R000786
Evaluate and explore the burden of sepsis and sepsis sequelae in the community using population-based cohorts in Africa.
REFNo: HS8549ES

General objective:
To evaluate and explore the burden of sepsis and sepsis sequelae in the community setting using a mixed methods approach.4.2. Specific objectives:
a) To develop a checklist to identify potential cases of sepsis and sepsis sequelae at the community level
b) To determine the burden (morbidity and mortality) of sepsis and sepsis sequelae using a community-based approach
c) To describe the social determinants of sepsis and sepsis deaths
d) To explore the barriers and facilitators to seeking healthcare services in patients with suspected sepsis and sepsis sequelae.

Uganda 2026-08-28 8:59:53 2029-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Evelyn Owomugisha
ID: UNCST-2026-R026496
Job-Study Balance and Persistence among In-Service Student Teachers in Public Universities in Uganda: The Intervening roles of Stress and Self-Efficacy
REFNo: SS5845ES

1.To investigate the extent to which perceived job-study balance predicts academic persistence among in service student teachers perusing professional development in Uganda. 2. To examine the mediating effect of stress on the relationship between job - study balance and academic persistence among in-service student teachers pursuing professional development in Uganda. 3. To determine the extent to which self-efficacy moderates the relationship between job-study balance and stress levels among in-service student teachers pursuing professional development in Uganda. 4. To develop a conceptual model illustrating the interplay between job-study balance, stress, self-efficacy, and persistence among in-service student teachers pursuing professional development in Uganda.
Uganda 2026-08-28 8:54:47 2029-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Victor Musiime -
ID: UNCST-2021-R013794
Developing a conceptual framework to guide the CLEAR-COPD-Kampala Study (Community Learning to Eliminate Air Pollution Risk among adolescents and young adults at risk for COPD in Kampala)
REFNo: HS8515ES

Overall objective: To develop a conceptual framework explaining facilitators and barriers to reducing personal air-pollution exposure among adolescents and young adults at risk for COPD in Kampala.

Specific aim: To conduct focus group discussions among adolescents and young adults, stratified by sex and socioeconomic status, to understand their knowledge, attitudes, perceptions, barriers, competing priorities, and facilitators related to reducing personal exposure to air pollution.
Uganda 2026-08-28 8:51:20 2029-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ssenoga Badru
ID: UNCST-2026-R026364
Development of Gritap AI, an Explainable Machine Learning Clinical Decision Support Tool for Predicting Viral Rebound and Virologic Failure in HIV-Positive Patients on Antiretroviral Therapy in Uganda: A Two-Phase Mixed-Methods Translational Health Informatics Study.
REFNo: SIR771ES

(1) To build, train, test and validate the ML model, using collected de-identified patient data. (2) To assess the explainability of the best-performing ML model, translating model internal feature attributions into clinician-readable explanations, using explainable AI techniques. (3) To assess the ML model`s usability, acceptability, and clinical-workflow fit of the tool among ART clinicians at a pilot site, using a usability and feedback questionnaire.
Uganda 2026-08-27 19:47:43 2029-08-27 Engineering and Technology Non-Clinical Trial Non-degree Award
Molly Nantongo
ID: UNCST-2026-R025337
Exploring the Role of Intimate Partner Violence (IPV) Shelters in Supporting Women’s Mental Health in Uganda. Phenomenological Qualitative.
REFNo: SS5804ES

To explore how women survivors of intimate partner violence living in IPV shelters in Uganda interpret and describe their experiences of the shelter environment and how these experiences influence their mental health and emotional well-being. To examine women survivors’ perceptions of the factors within the shelter environment that facilitate or hinder their mental health and emotional well-being. To explore key informants’ perceptions of the effectiveness of shelter-based services in supporting the mental health and emotional well-being of women survivors of IPV, and the factors that facilitate or hinder service provision.
Uganda 2026-08-27 19:43:42 2029-08-27 Social Science and Humanities Non-Clinical Trial Degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
Unpacking Constraints and Enablers of Disability Inclusion in Universal Parenting Interventions to Address Violence Against Children in Uganda (DIUPI)
REFNo: HS7344ES

Objectives
Overall goal
The research aims to generate an empirically grounded framework for mainstreaming disability inclusion in universal parenting programmes and produce actionable recommendations for implementation actors, by addressing the research question: What systemic factors hinder or enable disability inclusion within Uganda’s universal parenting programmes?
Objectives
1- In planning phase, how are disability-inclusive adaptations planned, and what shapes these decisions?
2- In implementation phase, how are inclusive practices operationalised during delivery?
3- What barriers and enablers influence participation and outcomes?
4- What are the barriers and enablers that affect equitable reach and safe participation of caregivers of children with disabilities across difficulties in parenting programmes?

Uganda 2026-08-27 19:41:24 2029-08-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
Usability Study for the Label Comprehension and Results Interpretation Study of Bioline™ Malaria Ag P.f/P.v Antigen Rapid Test & Results Interpretation Study of NxTek™ Malaria Pf Antigen Rapid Test
REFNo: HS8392ES

Primary Objectives
To assess whether intended users can locate, understand, and correctly apply critical
IFU and labelling information
• To assess whether intended users can accurately interpret test results (positive,
negative, invalid, faint/weak positive

Secondary Objective
• To evaluate effectiveness of IFU and labelling as risk control measures for identified
critical tasks
Uganda 2026-08-27 19:38:11 2029-08-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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