Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Onesmus Kamacooko
ID: UNCST-2023-R005897
Caregiver Mental Health, Family Structure, and Positive Parenting:Evidence from the Uganda Parenting for Respectability Program
REFNo: HS6902ES

i. To synthesize evidence on the effectiveness of parenting interventions in enhancing positive parenting practices among multiple caregivers of children aged 0–17 years in Sub-Saharan Africa through a systematic review. ii. To determine the factors associated with depression and anxiety among parents and caregivers of children aged 0-17 years in Uganda. iii. To investigate the longitudinal relationship between caregiver mental health and positive parenting practices over a 12-month follow-up period. iv. To examine the moderating role of family structure in the mediation relationship between intervention effects, caregiver mental health, and positive parenting practices.
Uganda 2026-04-10 17:39:00 2029-04-10 Medical and Health Sciences Non-Clinical Trial Degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
REDUCING TB MORTALITY DURING AND AFTER TREATMENT THROUGH SCREENING FOR KIDNEY DYSFUNCTION AND IMPLEMENTATION OF A MORTALITY RISK PREDICTION SCORE IN UGANDA
REFNo: HS7321ES

TO REDUCE TB MORTALITY DURING AND AFTER TREATMENT THROUGH SCREENING FOR KIDNEY DYSFUNCTION AND IMPLEMENTATION OF A MORTALITY RISK PREDICTION SCORE IN UGANDA,2. To explore patients’ views on the provision of nutritional support (meals) during TB care and its influence on adherence and recovery.(secondary),1. To explore healthcare workers’ perspectives on the ease of use and acceptability of point-of-care (POC) creatinine testing in TB care (Secondary),4. To determine one-year outcomes among patients admitted with TB and kidney disease. ,3. To introduce bedside point-of-care (POC) creatinine testing and assess the agreement between POC and laboratory-based creatinine tests in evaluating kidney function among adults admitted with TB,2. To revise the PROS score to include the optimal serum creatinine cut-off as a component and determine the accuracy of the revised score to predict TB mortality. ,To determine the optimal serum creatinine cut-off that predicts mortality among patients admitted with TB in Uganda. ,
Uganda 2026-04-10 17:37:08 2029-04-10 Medical and Health Sciences Non-degree Award
KIZZA GERALD
ID: UNCST-2021-R012792
An mHealth-Enabled Social Support Framework to Improve Anti-Diabetes Medication Adherence among Type 2 Diabetes Patients with HIV in Uganda
REFNo: SIR624ES

1. To develop an initial context specific implementation framework for utilizing a mobile phone–enabled social support intervention to enhance anti-diabetes medication adherence among type 2 diabetes patients living with HIV/AIDS in Uganda.

2. To co-design and co-develop an mHealth-enabled social support intervention for medication adherence among Type 2 diabetes patients living with HIV, drawing from the developed implementation framework.

3. To implement the developed intervention and assess its implementation outcomes guided by Proctor framework.

4. To explore the preliminary impact of the intervention on anti-diabetes medication adherence and glycaemic control among participants.

5. To develop an evidence based implementation framework (based on above findings) for utilizing a mobile phone–enabled social support intervention to enhance anti-diabetes medication adherence.

Uganda 2026-04-10 17:29:34 2029-04-10 Engineering and Technology Non-Clinical Trial Degree Award
ANDREW ACOBI
ID:
KNOWLEDGE, SKILLS, SELF-EFFICACY ON ADOPTION OF RESEARCH EVIDENCE IN PRACTICE AMONG NURSES AT LIRA REGIONAL REFERRAL HOSPITAL, LIRA, UGANDA.
REFNo: HS6844ES

Main Objective
To explore knowledge, skills, and self-efficacy on adopting research evidence in practice among nurses at Lira Regional Referral Hospital (LRRH), Lira City, Northern Uganda.
Specific Objectives or Core Objectives
1. To evaluate level of knowledge on the adoption of research evidence in practice among nurses at LRRH, Lira, Uganda.
2. To assess level of skills on the adoption of research evidence in practice among nurses at LRRH, Lira, Uganda.
3. To evaluate self-efficacy-related adoption of research evidence in practice among nurses at LRRH, Lira, Uganda.

4. To analyze the relationship between knowledge and adoption of research evidence in practice among nurses at LRRH, Lira, Uganda


Uganda 2026-04-10 17:28:22 2029-04-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Richard Katuramu
ID: UNCST-2022-R011266
Investigating the Consequences of USAID's suspension of HIV/AIDS Assistance in Tanzania and Uganda: A Multi-Stakeholder Qualitative Study in Uganda and Tanzania
REFNo: HS6630ES

1. To identify list of organizations/institutions previously funded by the USAID to implement different HIV/AIDS services
2. To explore the perception of the different stakeholders on the suspension of USAID funds for HIV/AIDS activities
3. To examine the short term strategies employed by the stakeholders to mitigate the impact of the suspension of USAID funds for HIV/AIDS activities
4. To explore the projected long-term consequences of this funding loss on the HIV/AIDS workforce, program delivery, research and sustainability
5. To assess the different reprioritization strategies and resource allocation in response to the reduced external assistance
6. To explore the different lessons from past funding disruptions and how they can be applied to improve future health system resilience
7. To examine the different roles, if any, do the stakeholders expect from alternative external donors like China

Uganda 2026-04-10 17:03:11 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CAROLINE KYOSIIMA MWEBESA
ID: UNCST-2026-R023538
Baseline and Endline Evaluation of Women's Economic Empowerment and Female Financial Health in Eastern Uganda (Kaliro and Namutumba Districts)
REFNo: SS5052ES

Objective 1 – Baseline documentation: To establish comprehensive baseline conditions (pre-intervention) regarding women's demographic characteristics, livelihood structures, economic activities and income sources, financial service access and financial behaviors, financial knowledge and digital literacy, household economic decision-making participation, gender relations and intra-household dynamics, and experiences of economic empowerment and disempowerment across both intervention and comparison groups in Kaliro and Namutumba districts. Objective 2 – Impact quantification: To measure the impact of WomenSave programming on women's financial inclusion outcomes (financial service access and productive usage), savings behaviors, economic income and diversification, and household economic decision-making participation over six-month and twelve-month periods when compared to similarly-situated a non-beneficiary comparison group. Objective 3: Mechanism exploration: To qualitatively examine the mechanisms through which WomenSave programming generates economic empowerment outcomes, including individual-level pathways, household-level pathways, and community-level pathways. Objective 4: Implementation and context factors: To document implementation realities, institutional coordination mechanisms, contextual enablers and barriers, and sustainability factors associated with WomenSave programming integration within PDM structures for program improvement, replication, and scaling.
Uganda 2026-04-10 16:52:20 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sandra Asizu
ID: UNCST-2026-R024434
BASELINE SURVEY FOR THE COLLECTIVE ACTION FOR DISABILITY RIGHTS PROGRAMME
REFNo: SS5049ES

I.Provide quantitative and qualitative baseline values for the programme’s outcome and impact indicators.
II.Assess the inclusivity and accessibility of education, health, economic, and social systems for persons with disabilities (PWDs).
III.Evaluate the institutional capacity and operational effectiveness of Organizations of Persons with Disabilities (OPDs).
IV.Inform programme implementation strategies, adaptive management, and subsequent endline evaluations.
Uganda 2026-04-10 16:26:42 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lydia Nakiyingi
ID: UNCST-2022-R010102
Investigating the Mycobacterium tuberculosis-respiratory viruses pathogenesis markers that can be explored for prognosis, diagnosis and disease progression during coinfections.
REFNo: HS7209ES

Primary Objective

-To investigate the pathogenesis markers associated with MTB-respiratory virus co-infection and explore their applications in prognostics, diagnostics, and disease management.

Secondary objectives:

-To identify respiratory viruses that are associated with TB-infected individuals in Makerere University clinical facility.

-To identify and characterize molecular and immunological markers associated with the interaction between MTB and respiratory viruses through immunological assays.

-To elucidate the mechanistic insights underlying the dysregulation of host immune responses in MTB-respiratory virus co-infection through transcriptomics tools.

-To design a statistical algorithm that can be a predictive model of TB-respiratory virus coinfections using immunological and transcriptomics data.

Uganda 2026-04-10 15:53:46 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Agaba Winston David
ID: UNCST-2026-R023332
TRANSFORMATION LEADERSHIP, ORGANIZATIONAL CULTURE AND ORGANIZATIONAL PERFORMANCE IN UGANDA’S PUBLIC AND COMMERCIAL BROADCASTING SECTOR
REFNo: SS4916ES

Aligned with the main objective, this study seeks to achieve the following: i. To examine the association between Idealized Influence and Organizational Performance in Uganda’s public and commercial broadcasting sectors. ii. To assess the relationship between Inspirational Motivation and Organizational Performance in Uganda’s public and commercial broadcasting sectors. iii. To analyze the influence of Intellectual Stimulation on Organizational Performance in Uganda’s public and commercial broadcasting sectors. iv. To evaluate the effect of Individualized Consideration on Organizational Performance in Uganda’s public and commercial broadcasting sectors. v. To investigate the moderating role of Organizational Culture on the relationship between Transformational Leadership and Organizational Performance in Uganda’s public and commercial broadcasting sectors. vi. To empirically develop and validate a conceptual model that integrates transformational leadership practices with supportive organizational culture to enhance organizational performance in Uganda’s public and commercial broadcasting sectors.
Uganda 2026-04-10 15:46:36 2029-04-10 Social Science and Humanities Non-Clinical Trial Degree Award
HARRIET NAMBUYA NIL
ID: UNCST-2021-R013414
Implementation of WHO minimum Maternal and Newborn Health data set in standardized Intrapartum care register and case notes at Jinja Regional Referral and Kamuli General Hospitals in Uganda
REFNo: HS7185ES

1.4 General objective
The aim of the study is to test improvement in the quality of routinely collected data elements necessary to monitor intrapartum maternal and immediate newborn health in hospitals from settings with high burden of maternal and newborn mortality and morbidities, upon implementation of a designed IPC register and obstetric CN.
1.5 Specific objectives of the study

1. To Design a globally standardized IPC register and selected obstetric CN for interprofessional teams involved in RHIS data collection and use in healthcare facilities
2. Test the feasibility and acceptability of implementing the designed IPC register and selected designed obstetric CN in selected healthcare facilities
a) Measure the completeness of intrapartum and immediate postnatal care data elements (including mMNHDS), documented before and after implementation of the designed register and CN.
b) Assess user-experience of the designed IPC register and CN.
c) Assess completeness and quality of the data elements required to inform the mMNHDS during intrapartum care depending on the level of care (lower level versus referral hospital).
3. Identify barriers and challenges encountered by health staff in implementing the standardized IPC register and obstetric case notes.

Uganda 2026-04-10 15:40:35 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
PATIENT AND PROVIDER PERCEPTIONS, EXPERIENCES, AND INTERVENTION SUGGESTIONS AFTER HIV/AIDS CARE FUNDING REDUCTIONS
REFNo: HS7138ES

To characterize comprehension of U.S. funding reduction for HIV/AIDS care and the implications on care among persons living with HIV.
2. To determine the initial impact of U.S. funding reductions for HIV/AIDS care by eliciting the experiences of persons living with HIV and their healthcare providers.
3. To understand perceptions regarding proposed or enacted interventions to maintain care after U.S. HIV/AIDS care funding reduction among providers and persons living with HIV.
Uganda 2026-04-10 15:36:15 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sserwadda Godfrey
ID: UNCST-2025-R021680
DIVERSITY OF PLANT-PARASITIC NEMATODES ASSOCIATED WITH TOMATOES AND THEIR CONTROL USING SELECTED PLANTS IN WAKISO DISTRICT
REFNo: NS1144ES

To determine the different agricultural management practices used by tomato farmers in Namayumba Subcounty district To determine diversity of plant parasitic nematodes infesting tomatoes in Namayumba Sub county; Wakiso district To determine efficacy of Tagetes patula L., Parthenium hysterophorus. Ricinus communis L., and Allium sativa ethanol, methanol, acetonitrile, and aqueous extracts against plant parasitic nematodes associated with tomatoes
Uganda 2026-04-10 15:24:25 2029-04-10 Natural Sciences Non-Clinical Trial Degree Award
RaidaAli Mudei Ahmed
ID: UNCST-2025-R020851
ASSOCIATION BETWEEN ABNORMAL CEREBROPLACENTAL RATIO AND ADVERSE NEONATAL OUTCOMES AMONG WOMEN WITH POSTDATE PREGNANCIES DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS7137ES

To determine the association between abnormal cerebroplacental ratio and adverse neonatal outcomes among women with postdate pregnancies delivering at Mbarara Regional Referral Hospital.
Somalia 2026-04-10 15:20:19 2029-04-10 Medical and Health Sciences Non-Clinical Trial Degree Award
HARRIET NANKYA
ID:
Ethical Issues in Adopting Artificial Intelligence for Health Management in a Low Resource Setting: A case of AI-based TB Diagnosis in Uganda
REFNo: HS7022ES

1. To investigate the ethical challenges faced by AI developers at Makerere University in
developing AI-based tools for TB diagnosis.
7
2. To examine the ethical challenges faced by healthcare workers in Kampala in applying AI
based tools for TB diagnosis.
3. To analyze the views of AI developers and health workers on the measures to address the
ethical challenges in adopting AI for TB diagnosis in Uganda.
Uganda 2026-04-10 15:17:34 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
THE EFFECT OF CONSUMING MEALWORM ENRICHED FLOUR ON THE NUTRITIONAL STATUS OF ADOLESCENTS AT BUJUBULI SECONDARY SCHOOL IN KYEGEGWA DISTRICT
REFNo: HS6905ES

To determine the effect of providing mealworm enriched meals on the nutritional status of adolescents in Bujubuli secondary school in Kyegegwa district,To assess the nutritional status of children at Bujubuli Secondary School in Kyegegwa District. ,To develop a nutritious mealworm-enriched flour suitable and acceptable for school adolescents at Bujubuli secondary school in Kyegegwa district ,To assess the effect of consuming mealworm-enriched flour on the nutritional status of adolescents 12-19 at Bujubuli secondary school in Kyegegwa District through a randomized controlled trial.,
Uganda 2026-04-10 15:09:16 2029-04-10 Medical and Health Sciences Non-degree Award
JOEL KASIBANTE ALBERT
ID: UNCST-2025-R022443
MIXED-METHODS IMPACT EVALUATION OF THE DIMITRA CLUBS PROJECT IN UGANDA’S AMOLATAR DISTRICT
REFNo: SS4697ES

Main Objective / Purpose The impact evaluation seeks to understand how participation in Dimitra Clubs influences women’s empowerment and social inclusion. It will assess changes in social cohesion—such as trust, community participation, collective problem-solving, and conflict resolution. The evaluation will further examine how the Clubs strengthen women’s agency, confidence, decision-making power, and access to social and economic resources, while also observing shifts in gender norms among both women and men. Lastly, the study aims to determine whether involvement in the Clubs reduces experiences of intimate partner violence. Specific Objectives (Polished & Summarised) 1. To evaluate how the Dimitra Clubs enhance women’s intrinsic agency, including autonomy over income decisions and overall self-efficacy. 2. To explore changes in intra-household gender dynamics, including men’s engagement in domestic roles and how household resources are controlled or allocated. 3. To determine whether participation in the Clubs is associated with a reduction in intimate partner violence. 4. To assess the influence of the Clubs on participants’ social cohesion, focusing on trust, relationships, community participation, and confidence in local institutions.
Uganda 2026-04-10 14:58:12 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Anguzu John
ID: UNCST-2024-R015949
Development of cassava agro-industrialization in Uganda: An innovation systems perspective.
REFNo: A531ES

1. Establsih the roles and interactions of key actors in the context of cassava agro-industrialization in Uganda.
2. Examine how the systemic bottlenecks in cassava innovation system affect the development of cassava agro-industrialization.
3. Explore the effectiveness of linkages between agro-industries and community- based value addition actors in promoting cassava agro-industrialization.
4. Establish the suitability of existing policy context and incentive systems in promoting the development of cassava agro-industrialization.
Uganda 2026-04-10 14:51:58 2029-04-10 Agricultural Sciences Non-Clinical Trial Degree Award
DOROTHY EGO AKAO
ID: UNCST-2026-R023556
ASSESSMENT OF THE QUALITY OF UNDERGROUND WATER CONSUMED BY GULU UNIVERSITY COMMUNITY USING WATER QUALITY INDEX
REFNo: NS1211ES

1. To identify anthropogenic factors that affect the quality of underground water in Gulu University community. 2. To determine physico-chemical parameters (DO, COD, BOD, pH, temperature, electrical conductivity, nitrates, turbidity, phosphates and hardness) in the underground water consumed by Gulu University community. 3. To determine the microbiological parameters in the underground water consumed by Gulu University community.
Uganda 2026-04-02 18:01:31 2029-04-02 Natural Sciences Non-Clinical Trial Degree Award
Justine Nakintu
ID: UNCST-2019-R001223
Nutrient enrichment of Maize Flour for a Dietary Balanced Breakfast: Fortification with Jackfruit
REFNo: A747ES

i. To determine concentrations of proteins, vitamins, minerals and phytochemicals in the different varieties of jackfruit
ii. To fortify maize flour with different proportions of jackfruit and determine the concentrations of proteins, vitamins, mineral and other phytochemicals in un-fortified maize flour and jackfruit-fortified maize flour
iii. To establish the sensory acceptability of porridge made from jackfruit fortified maize flour

2026-04-02 18:00:32 2029-04-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Lynn Tar Janet Gutu
ID:
An AI system to assist the visually and auditory impaired by generating speech from text queries and vice versa for Uganda’s local languages
REFNo: SIR633ES

To pen source the collected linguistic datasets and baseline models to support future research, foster collaboration, and create a foundation for broader AI innovation in low-resource languages.,To develop and deploy a user-friendly platform that enables easy and inclusive access to the system for impaired and non-impaired users alike.,To build and train multilingual TTS and LLM models for at least five Ugandan languages. ,To develop and deploy a locally managed AI system with multilingual TTS and LLM capabilities that supports Uganda’s most widely spoken indigenous languages, with a particular focus on enhancing accessibility for visually and auditory impaired communities, while promoting inclusivity, education, and digital innovation.,
Uganda 2026-04-02 17:59:20 2029-04-02 Engineering and Technology Non-degree Award
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