Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
FRANCIS  AMAYOA ANYAKA
ID: UNCST-2024-R003877
INTEGRATING ENVIRONMENTAL SUSTAINABILITY INTO RESEARCH ETHICS REVIEW IN UGANDA: PERSPECTIVES OF RESEARCH ETHICS COMMITTEE MEMBERS.
REFNo: HS7784ES

General Objective To assess the awareness, attitudes, and practices of RECs regarding environmental sustainability, and to identify practical strategies for enhancing its integration into research ethics review. Specific Objectives 1. To assess awareness among REC members regarding environmental sustainability in research. 2. To examine the attitudes and perceptions of REC members toward incorporating environmental sustainability into ethics review processes. 3. To assess current practices for integration of environmental considerations into REC ethics review processes. 4. To identify the barriers and facilitators that influence the integration of environmental sustainability into research ethics review by RECs. 5. To propose strategies for strengthening ethical oversight systems to effectively incorporate environmental sustainability into research governance.
Uganda 2026-05-28 15:58:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alex Saturday
ID: UNCST-2023-R007459
Effect of Land Use on Water Quality and Biotic Assemblages of Lake Nyabihoko, Western Uganda
REFNo: NS1120ES

i) To assess LULC change patterns from 1992 to 2022 (i.e., 1992, 2002, 2012, and 2022) in the Lake Nyabihoko sub-catchment.
ii) To investigate the spatial and seasonal variability in the physicochemical (i.e., turbidity, temp, DO, EC, pH, TDS, TP, TN, NH4-N, and NO3-N) parameters of water in Lake Nyabihoko.
iii) To investigate spatial and seasonal variability in macroinvertebrate composition, abundance, and diversity in the study area
iv) To investigate phytoplankton composition, abundance, diversity and biomass between wet and dry seasons and among the study stations.

Uganda 2026-05-28 15:48:35 2029-05-28 Natural Sciences Non-Clinical Trial Degree Award
Dan Ngabirano
ID: UNCST-2025-R021195
Beyond Legal and other Formal Approaches to the Grand Corruption Problem in Uganda: The Role of Indigenous African Customary Laws, Norms and Institutions
REFNo: SS4691ES

a) To study and document the strength and limitations of relying on legal and other formal approaches to grand corruption in Uganda. b) To interrogate the efficacy of customary laws, norms and institutions in the fight against grand corruption while relying on case studies from Buganda, Bunyoro, Bugisu, Acholi, Kigezi Tswana and Asante societies c)To inquire into the practicability of relying on customary laws, norms and institutions in the fight against corruption in Uganda and whether these should exist as alternatives or rather compliment current legal and formal approaches.
Uganda 2026-05-28 15:46:29 2029-05-28 Social Science and Humanities Non-Clinical Trial Degree Award
Opar BernardToliva
ID: UNCST-2026-R023349
ASSESSING THE BURDEN AND RESEARCH CAPACITY ON SNAKEBITE ENVENOMING IN NORTHERN UGANDA
REFNo: HS7038ES

To assess the hospital incidence, clinical management practices, and research capacity for snakebite envenoming in Uganda, with the aim of identifying potential clinical trial sites for an upcoming antivenom clinical trial.
Uganda 2026-05-28 15:42:48 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOSHUA KIPTOO
ID: UNCST-2025-R021984
Use of Physiologically Based Pharmacokinetic (PBPK) Modelling Approach to Predict Infant Exposure to Bedaquiline, Lamivudine, and Lumefantrine Via Breastmilk
REFNo: HS7748ES

General Objective: To determine infant plasma exposure to Lamivudine, Lumefantrine, and Bedaquiline via breast milk change over the first year of life (0-12 months) Specific objectives 1. To develop a PBPK model for the prediction of infant plasma exposure to Bedaquiline, Lamivudine, and Lumefantrine via breast milk 2. To determine the variability in infant plasma exposure to Bedaquiline, Lamivudine, and Lumefantrine via breast milk during the first year of life (0-12 months)
Uganda 2026-05-28 15:39:46 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
Field Performance Verification of the XL1000e Automated Blood Coagulation Analyzer at Health facilities in Uganda: A Method Verification and Comparative Evaluation Study
REFNo: HS7524ES

To determine the operational characteristics and user satisfaction associated with the XL1000e. To conduct a method comparison between the XL1000e and the Sysmex CA-660/CS510 analyzer as a reference using patient samples. To evaluate the analytical performance (precision, accuracy, carryover, linearity) of the XL1000e in measuring Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Thrombin Time (TT), Fibrinogen (FIB), and D-dimer.
Uganda 2026-05-28 15:38:43 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Otim
ID: UNCST-2024-R016522
Item Bank Development for Paediatric Malignancies: A Tool for Quality-of-Life Evaluation and Prognostic Prediction in Northern Ugandan Children.
REFNo: HS7281ES

Primary Objective: Develop an item bank for pain, nausea, loss of appetite, physical functioning, cognitive impairment, sleep quality and fatigue among children with cancer.
Secondary Objectives: (i)Correlate tumour size, serum LDH levels and patient quality of life among children with cancer.
(ii) Explore using self-reported measures to predict prognosis in children with cancer during chemotherapy.
Uganda 2026-05-28 15:35:44 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Haliima Nalugo
ID: UNCST-2025-R020120
Seroprevalence and Molecular Detection of Brucella Species in Archived Wildlife Samples at Queen Elizabeth National Park (QENP), Uganda
REFNo: HS7529ES

To estimate the seroprevalence and detect Brucella species among selected wildlife species in Queen Elizabeth National Park
Uganda 2026-05-28 15:32:04 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Oscass Jimmy  Ruva
ID:
Moral Beliefs, Clinical Discretion, and Behaviour Change Interventions: Understanding Provider-Driven Rationing of Post-Abortion Care in Uganda’s Restrictive and Fragile Health System.
REFNo: HS7425ES


To describe providers’ Moral Beliefs and Clinical Discretion shape the rationing of post-abortion care in Uganda’s Restrictive and Fragile Health System, and how trainings and behaviour change interventions influence these practices
Uganda 2026-05-28 15:30:30 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Eve  Namisango
ID: UNCST-2021-R014038
Palliative care needs of children and young people living with serious illnesses and their families in Uganda
REFNo: SS5166ES

How do the palliative care needs of children and young people living with serious illnesses change over time? ,What are the palliative care needs of children and young people living with serious illnesses in Uganda? ,
Uganda 2026-05-28 15:29:15 2029-05-28 Social Science and Humanities Non-degree Award
Lorna Atikoro
ID: UNCST-2024-R002527
REDUCING THE BURDEN OF METHICILLIN RESISTANT Staphylococcus aureus (MRSA) INFECTIONS IN UGANDAN PATIENTS RECEIVING HAEMODIALYSIS
REFNo: HS7485ES

1. To estimate the prevalence of MRSA carriage among patients receiving chronic haemodialysis at Kiruddu National Referral Hospital.
2. To determine the factors associated with MRSA carriage among patients receiving chronic haemodialysis at Kiruddu National Referral Hospital.
3. To determine the success rate of mupirocin ointment in eradicating nasal carriage of MRSA among patients receiving chronic haemodialysis at Kiruddu National Referral Hospital

Uganda 2026-05-28 15:23:03 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank Kaharuza Mugisha
ID: UNCST-2025-R022389
ASSESSING THE CONTRIBUTION OF THE SAFE BIRTH AFRICA (SBA) PROJECT IN UGANDA: AN IMPLEMENTATION RESEARCH STUDY ON HEAT-STABLE CARBETOCIN AND TRANEXAMIC ACID FOR POSTPARTUM HAEMORRHAGE PREVENTION AND TREATMENT
REFNo: HS7496ES

The General objective is to generate evidence on the implementation effectiveness and contribution of the Safe Birth Africa project in improving equitable access to and utilization of HSC and TXA for postpartum haemorrhage prevention and treatment in Busoga region and Kampala, Uganda. The specific objectives are 1. To assess the implementation fidelity of SBA interventions (HSC and TXA) across different health facility levels in Busoga region and Kampala. 2. To explore the facilitators and barriers to implementation of the SBA interventions across the pilot sites and regions. 3. To understand health worker experience in the use of HSC for prevention and TXA for treatment of PPH.
Uganda 2026-05-28 15:11:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Russell Morton
ID: UNCST-2026-R024044
Born Safe or Made Safe? The Role of Market Organization in Uganda's Informal Transit Sector
REFNo: SS5155ES

Main Objective 1. To examines how market organization affects safety provision in Uganda\'s informal motorcycle taxi (boda boda) sector. 2. To evaluate the feasibility of experimental design and data collection procedures. 3. To measure stage selection of drivers by analyzing how stage managers\' rankings of potential entrants correlate with driver safety characteristics 4. To Estimate driver self-selection into organized boda stages by measuring the relationship between baseline driving behavior and drivers\' willingness to join stages 5. To Estimate the causal treatment effect of stage membership on driving behavior using randomized subsidies for stage entry fees Specific Objectives 1. Our specific objectives of this program include learning about the safety of boda drivers, how stages affect boda driver behaviors, how boda drivers of different safety sort into joining stages or working as lubyanza drivers, and how passengers think about boda safety and associated implications for incentives for drivers to behave safely. We also analyze how stage organization and behaviors are related to safety at the stage
United States of America 2026-05-28 15:05:57 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Evaluation of the Building Tomorrow NRD Program in Uganda
REFNo: SS5321ES

The primary objective of this study is to assess changes in learners’ numeracy scores and determine the extent to which these changes can be attributed to the BT NRD intervention. ,
Uganda 2026-05-28 15:03:18 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Davies Otieno
ID: UNCST-2025-R021802
Development of a maternal sepsis model using a physiologically based pharmacokinetic approach
REFNo: HS7463ES


Kenya 2026-05-28 15:00:25 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
GASTONE HABARUGABA
ID: UNCST-2025-R017858
CLIMATE VARIABILITY AND SMALLHOLDER FARMER LIVELIHOODS IN THE MOUNTAIN AGRO ECOLOGICAL ZONE OF RUBANDA DISTRICT, WESTERN UGANDA.INTEGRATING SOCIO-ECOLOGICAL SYSTEMS APPROACH FOR MITIGATION
REFNo: NS1239ES

To analyse the trend of climate variability in Rubanda from 1993-2024 2-To examine smallholder farmers’ vulnerability to climate variability in Rubanda 3- To analyse the impact of climate variability on food security status of smallholder farmers in Rubanda 4- To assess the impact of climate variability on rural forest livelihoods of smallholder farmers in Rubanda 5- To ascertain sustainable socio-ecological climate variability adaptation approaches for agroecological balance in Rubanda
Uganda 2026-05-22 19:38:44 2029-05-22 Natural Sciences Degree Award
Henry Mugerwa
ID: UNCST-2019-R000420
A Phase I/II clinical study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of ITU512 in healthy participants and patients with sickle cell disease
REFNo: HS6925ES

1.To assess the safety and tolerability
of ITU512 in healthy participants
2.To assess the safety and tolerability
of ITU512 in participants with SCD
3.To assess the effect of ITU512 on
fetal hemoglobin expression

Uganda 2026-05-22 16:52:18 2029-05-22 Medical and Health Sciences Clinical Trial Non-degree Award
Michael King
ID: UNCST-2026-R023619
Gender Focused Multi-Faceted Anti-Poverty Programs: Low-Cost Options for Scale-up
REFNo: SS5152ES

• To estimate the causal impact of adding a community-level gender empowerment intervention to the standard VE graduation programme on women’s agency, intra-household decision-making, and household economic outcomes. • To estimate the additional (marginal) impact of complementing community-level interventions with household-level couples training on the same outcomes. • To identify how gender-transformative interventions affect the process of intra-household decision-making by decomposing decisions into stages (initiation, discussion, agreement, implementation). • To assess whether observed changes in decision-making reflect improvements in women’s empowerment, household cooperation, or both. • To evaluate the effects of the interventions on household risk management, including both ex-ante preparation (e.g. savings, planning) and ex-post coping strategies (e.g. asset sales, borrowing). • To test a trauma-sensitive survey innovation in measuring intimate partner violence (IPV), specifically a “stop rule” approach, and assess its effects on respondent burden, survey fatigue, and data quality. • To assess the cost-effectiveness and scalability of gender-transformative additions to graduation-style programmes for policy and implementation contexts.
Ireland 2026-05-21 9:55:20 2029-05-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vicent Rutagangibwa
ID: UNCST-2022-R010288
Exploring Variation in How Sustainability is Experienced in Ugandan Engineering Education: A Phenomenographic Study
REFNo: SIR636ES

The overall objective of this study is to examine how sustainability is conceived, formally represented, and experienced across institutional, curricular, and pedagogical dimensions within Ugandan engineering education, focusing on the views of both faculty and students. Specifically, the study seeks: (1) to determine the extent and ways sustainability is reflected in the institutional and curricular documents of MUST’s engineering programmes; (2) to explore the varied ways engineering students at MUST conceive and experience sustainability in their education; and (3) to explore the varied ways engineering faculty at MUST conceive sustainability and integrate it into their teaching and learning activities.
Uganda 2026-05-21 9:41:21 2029-05-21 Engineering and Technology Non-Clinical Trial Degree Award
Silver Onyango
ID: UNCST-2022-R009337
A PILOT STUDY ON USING LOW-COST AIR QUALITY SENSORS TO INFLUENCE COOKING BEHAVIOR IN GREATER MASAKA REGION, UGANDA.
REFNo: HS7732ES

Evaluate the operation of air quality warning displays and participant response to their installation. ,Evaluate the performance of heat, motion, and location sensors in recording cooking behaviors in Masaka, Uganda. ,Evaluate the performance of low-cost PM and CO monitors in estimating air quality in kitchens in Masaka, Uganda.,i. Evaluate the performance of low-cost PM and CO monitors in estimating air quality in kitchens in Masaka, Uganda.,Evaluate the performance of low-cost air quality sensors, cooking behavior sensors, and feedback displays in Masaka, Uganda. ,
Uganda 2026-05-21 9:25:38 2029-05-21 Medical and Health Sciences Non-degree Award
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