Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Akankwatsa Dickson
ID: UNCST-2025-R020428
 ASSESSING CAPACITIES OF BORDER PROXIMAL HEALTH FACILITIES TO TACKLE EPIDEMIC PRONE DISEASES: A CASE STUDY OF THE WEST NILE REGION OF UGANDA
REFNo: HS6771ES

1. To assess the preparedness and response capacities of border proximal health facilities to manage ill travellers suspected of epidemic prone diseases along the West Nile region, Uganda. 2. To establish the challenges faced by boarder health facilities along the West Nile region of Uganda, in detection and management of ill travellers suspected of epidemic prone diseases
Uganda 2025-12-10 20:11:42 2028-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ASINGWIRE JENINAH FLAVIA
ID: UNCST-2024-R003589
 Perceived Psychosocial Classroom Learning Environment, Academic Interest and Academic Achievement in Mathematics among students in Secondary Schools in Greater Mbarara Region
REFNo: SS4695ES

1. To evaluate the influence of changes in the perceived classroom learning environment on academic achievement in mathematics among secondary school students in Greater Mbarara.
2. To examine the relationship between changes in the perceived classroom learning environment and changes in academic interest in mathematics among secondary school students in Greater Mbarara.
3. To assess whether change in academic interest mediates the relationship between changes in the perceived classroom environment and change in academic achievement in mathematics among secondary school student in greater Mbarara.
4. To compare changes in academic interest and changes in academic achievement in mathematics between groups of students categorized by their perceived classroom learning environment quality

Uganda 2025-12-10 20:07:48 2028-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
INNOCENT BWENGYE
ID: UNCST-2025-R019226
 OPTIMIZATION OF FEW-SHOT LEARNING MODELS FOR CLASSIFICATION AND RANKING OF BIOMATERIALS FOR BONE TISSUE ENGINEERING
REFNo: SIR592ES

The general objective of this study is to improve the process of selecting biomaterials for bone tissue engineering by developing a few-shot learning model that leverages Bayesian optimization to identify optimal hyperparameters, addressing data scarcity challenges and enhancing model accuracy, generalizability, and computational efficiency.

SPECIFIC OBJECTIVES
I. To critically evaluate existing few-shot learning techniques, analyzing their architectures, strengths, and limitations, with a specific focus on their applicability to biomaterial classification and ranking in bone tissue engineering.
ii.To design and implement a Bayesian-optimized few-shot learning model that effectively learns from limited data and provides robust uncertainty quantification in predictions for BTE applications.
iii.To integrate transfer learning techniques into the Bayesian-optimized few-shot learning framework to enhance its performance and adaptability to biomaterial datasets with diverse mechanical properties.
iv.To evaluate the performance of the proposed model on classification and ranking tasks specific to bone tissue engineering

 Uganda 2025-12-10 19:58:41 2028-12-10 Engineering and Technology Non-Clinical Trial Degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 Empowering Women for Better Reproductive Health Outcomes (EMPOWER): Monitoring, Evaluation, Research and Learning
REFNo: SS4684ES

4. To generate rapid operational research and learning agenda.,3. To assess the quality and completeness of programme data by conducting periodic data quality assessments (DQA) and verifying the accuracy and attribution of results reported,2. To determine baseline values for key RMNCAH service coverage, quality-of-care, and health system indicators across participating facilities, providers, and client populations.,1. To validate EMPOWER’s Theory of Change, Results Framework and Logframe to ensure that indicators, assumptions, and data sources are appropriate, measurable, and aligned with national RMNCAH priorities.,The purpose of this study is to monitor, evaluate, and generate evidence on the design, implementation, and outcomes of the EMPOWER programme in order to strengthen accountability and inform adaptive management to improve RMNCAH outcomes in Uganda.,
 Uganda 2025-12-08 12:54:10 2028-12-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Milton Musaba Wamboko
ID: UNCST-2019-R000825
 High-Performance, Multivariate, Accessible Tools for Early HMB Identification and Iron Deficiency Risk Prediction (VITAL-HMB)
REFNo: HS6715ES

1. to develop and validate biomarkers and risk factors that accurately identify women at risk of heavy HMB and iron deficiency complications, thereby enabling earlier diagnosis, targeted intervention and improved health outcomes for HMB affected women across diverse healthcare settings.
 Uganda 2025-12-08 12:43:39 2028-12-08 Medical and Health Sciences Non-degree Award
STEVEN SEBBALE
ID: UNCST-2023-R006063
 Investment in Research and National Development in Uganda: A Case of projects in the Science Granting Councils Initiative
REFNo: SS4681ES

1. To Classify Uganda's research by field and type and examine the contribution of research indicators such as employment, innovation and knowledge development
2. To Estimate Return on Investment of Research by type in scientific field as well as national level
3. Predict Return on Investment for a given range of investment amounts over 5, 10 and 15 year periods
 Uganda 2025-12-05 19:24:37 2028-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Barriers to effective utilization of vaccines and immunization services In Uganda- A qualitative Assessment
REFNo: HS6784ES

a) To explore socio-demographic characteristics affecting access to immunization services in Uganda.
b) To explore health facility characteristics affecting access to immunization services in Uganda.
c) To explore geographical and community level characteristics affecting access to immunization services in Uganda.
d) To explore and identify policy gaps affecting access to immunization services in Uganda.

 Uganda 2025-12-05 19:19:05 2028-12-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Developing and refining REConneCteD: a digitally integrated post-discharge care intervention for children in East Africa
REFNo: HS6806ES

Iteratively test and refine the integrated post-discharge care intervention and associated implementation resources through usability assessments and pilot testing,Build the necessary technical components and implementation resources (such as training materials and counseling guides) to enable functionally effective integration of the intervention within both facility and community settings,Develop the community-based post-discharge bundle of interventions, including workflows, care delivery materials, and associated training material, Develop the facility-based post-discharge bundle of interventions, including workflows, care delivery materials, and associated training material,The main objective of this formative research phase is to develop and refine a comprehensive, integrated post-discharge bundle of interventions for high-risk children that spans both facility and community settings,
 Uganda 2025-12-05 19:15:17 2028-12-05 Medical and Health Sciences Non-degree Award
AMPAIRE WYCLIFFE
ID: UNCST-2025-R017187
 SOURCE APPORTIONMENT AND BIODEGRADATION OF PAHs AND PFAS FROM WATER AND SEDIMENTS ALONG L. ALBERT
REFNo: NS1070ES

i. To determine the concentrations of 25 selected PAHs and 18 PFAS in water and sediment samples from Lake Albert using GC-MS/MS and LC-MS/MS, respectively.
ii. To identify the potential sources and spatial distribution patterns of PAHs and PFAS in Lake Albert using principal component analysis (PCA), HCA multivariate statistical techniques, and a fugacity-based model.
iii. To evaluate the human and ecological health risks posed by combined PAH and PFAS contamination in Lake Albert, using the US EPA Exposure Factors Handbook for risk characterization.
iv. To come up with potential biodegradation pathways for one selected PAH and one selected PFAS compound identified in water and sediment samples.

 Uganda 2025-12-05 19:12:24 2028-12-05 Natural Sciences Non-Clinical Trial Degree Award
JESSE LIMO MWANGA
ID: UNCST-2025-R019331
 Development of a web-based project management application to enhance construction project performance
REFNo: SS4618ES

I. To determine the gaps in existing project management applications based on stakeholder requirements. II. To design a prototype web-based project management application that addresses the gaps in existing applications based on stakeholder requirements. III. To assess the effectiveness of the prototype web-based project management application in addressing the gaps in existing applications and enhancing construction project performance in Uganda.
Uganda 2025-12-05 19:08:11 2028-12-05 Social Science and Humanities Non-Clinical Trial Degree Award
Rebecca Nuwematsiko
ID: UNCST-2022-R010501
 Prescribing and dispensing practices of antimicrobials and drivers for inappropriate use among staff in licensed private retail pharmacies in Kampala and Mbarara cities, Uganda
REFNo: HS6581ES

o explore drivers of inappropriate use of antimicrobials in licensed private retail community pharmacies in Kampala and Mbarara cities,To assess antimicrobial prescribing and dispensing practices among staff in licensed private retail community pharmacies in Kampala and Mbarara cities.,To determine the level of knowledge and perceptions on antimicrobial resistance among staff in licensed private retail community pharmacies in Kampala and Mbarara cities.,To assess antimicrobial prescribing and dispensing practices and drivers of inappropriate use among staff in selected licensed private retail community pharmacies in Kampala and Mbarara cities in Uganda so as to add on the available evidence for fostering antibiotic stewardship in private pharmacies.,
 Uganda 2025-12-05 18:44:34 2028-12-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emma Wamono
ID: UNCST-2025-R017178
 Impact of anthropogenic stressors on ecosystem health and potential in-stream restoration measures of river Manafwa catchment in eastern Uganda
REFNo: NS993ES

I.Examine the influence of anthropogenic stressors on Physico-chemical water quality parameters in river Manafwa catchment in eastern Uganda. II.Analyse the influence of anthropogenic stressors on the macroinvertebrate assemblages in river Manafwa catchment in eastern Uganda. III.Asses the community perception on how their activities affect aquatic ecosystem health in river Manafwa catchment in eastern Uganda. IV.Establish and asses the performance of selected restoration measures in enhancing river ecosystem health in river Manafwa catchment in eastern Uganda.
Uganda 2025-12-05 18:39:17 2028-12-05 Natural Sciences Non-Clinical Trial Degree Award
Emmanuel  Luyirika BK
ID: UNCST-2025-R021521
 Destigmatizing Breast Cancer: Village Health Teams Using a Video Education Tool
REFNo: SS4394ES

1)Improve knowledge about breast cancer among VHTs 2)Evaluate if community members found this video tool to be an acceptable and helpful way to learn more about breast cancer. 3)Evaluate if VHTs found this video tool to be an acceptable and helpful way to share information about breast cancer.
Uganda 2025-12-05 18:37:27 2028-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening (SIMCS)- A Cluster Randomized Trial
REFNo: HS6567ES

(ii) To evaluate the impact of the SCD SIMCS on access to screening and care and outcomes of children with SCD,
 Uganda 2025-12-05 18:30:02 2028-12-05 Medical and Health Sciences Clinical Trial Non-degree Award
Julius Ssendiwala
ID:
EVALUATION OF HIV INTEGRATION INTO ROUTINE CARE AT HEALTH FACILITIES IN UGANDA: LESSONS LEARNT FROM -THE COVID-19 HIV SERVICE DELIVERY ADAPTATIONS AND THE US PRESIDENT EXECUTIVE ORDERS
REFNo: HS6720ES

1. To document the health system adaptations that occurred during the COVID-19 pandemic, and the recent US President Executive Orders and how are they are being utilized for current HIV integration efforts?
2. To document the various models of HIV integration currently being implemented, and the factors that facilitate or hinder their successful implementation
3. To assess the uptake, feasibility, and acceptability of integrating HIV services into routine healthcare services

 Uganda 2025-12-03 18:46:20 2028-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 VALIDATION OF AN OFFLINE DEEP – LEARNING AI MODEL FOR ESTIMATING FVC AND FEV₁ FROM CHEST X‑RAYS IN A RESOURCE‑LIMITED UGANDAN CLINICAL SETTING.
REFNo: HS6703ES

Primary Objective
To evaluate the accuracy of an offline, deep-learning AI model in estimating forced vital capacity (FVC) and forced expiratory volume in one second (FEV₁) by comparing AI-predicted values against spirometry-measured values.

Secondary Objective
To determine the agreement between AI-derived and spirometry-derived FEV₁/FVC ratios, and assess its utility for identifying airflow obstruction (i.e., FEV₁/FVC < 0.70).
 Uganda 2025-12-01 22:01:17 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
 Exploring Factors Influencing COVID-19 Vaccination Uptake: A Qualitative Study in Uganda
REFNo: SS4582ES

To explore the factors and contextual differences that influenced COVID-19 vaccination uptake in Uganda, to compare these with experiences in Burundi and Rwanda, and to identify key predictors and opportunities for regional learning
 Kenya 2025-12-01 21:44:17 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
STELLA NABIRYE
ID: UNCST-2024-R003637
 Evaluation of outcomes of anticoagulation and factors associated with Time in Therapeutic Range among Rheumatic heart disease patients on vitamin K antagonists attending care at the Uganda Heart institute
REFNo: HS6728ES

General objective
To evaluate the outcomes of anticoagulation and factors associated with time in therapeutic range among Rheumatic heart disease patients on vitamin K antagonist attending care at Uganda Heart Institute

specific objectives
1.To determine the clinical outcomes of anticoagulation among Rheumatic heart disease patients on vitamin K antagonists attending care at Uganda Heart Institute

2.To determine the factors associated with time in therapeutic range among Rheumatic disease patients on vitamin K antagonists attending care at Uganda Heart Institute

3.To explore patients’ attitudes and knowledge on the use of vitamin K antagonists among Rheumatic heart disease patients attending care at Uganda Heart Institute

4.To explore clinicians’ perception of the use of vitamin K antagonists in managing patients with Rheumatic heart disease attending care at Uganda Heart Institute
 Uganda 2025-12-01 21:35:22 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
ATUHAIRE JUSTUS
ID: UNCST-2024-R004914
 Improving the quality of face sheet completion at Mulago National Referral Hospital
REFNo: HS6627ES

1. To determine the proportion of face sheet that are not complete at Mulago National Referral Hospital. 2. To identify the factors that contribute to failure of doctors to complete face sheet at Mulago National Referral Hospital. 3. To identify the measures that can be put forward towards completion of face sheet at Mulago National Referral Hospital.
Uganda 2025-12-01 21:28:40 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mirembe SarahAngella
ID: UNCST-2025-R021000
 Influence of Women's Participation In The Rice Value Chain on Household Dietary Diversity in Eastern Uganda
REFNo: SS4586ES

1. To examine the extent of women’s participation in the rice production, processing, and marketing activities within selected rice-oriented households in Namasagali sub-county, Eastern Uganda. 2. To identify the institutional factors that influence women’s participation as rice value chain actors at the household level. 3. To assess the dietary diversity of rice-oriented households in Namasagali sub-county, Eastern Uganda. 4. To establish a relationship between women’s participation and household dietary diversity.
 Uganda 2025-12-01 21:16:33 2028-12-01 Social Science and Humanities Degree Award
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