Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
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PREVALENCE, CORRELATES AND EXPLANATIONS OF A LONG DURATION OF UNTREATED PSYCHOSIS AMONG ANTIPSYCHOTIC NAÃVE PATIENTS AT BUTABIKA HOSPITAL: A MIXED METHODS STUDY.
REFNo: HS237ES
1. To determine the prevalence and factors associated with a long duration of untreated psychosis among patients with a first episode psychosis at Butabika hospital in Uganda.
2. Achieve a qualitative understanding of influence of prior treatment with alternative and complimentary therapies on duration of untreated psychosis among patients with a first episode of psychosis (FEP) presenting to Butabika hospital in Uganda.
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Uganda |
2019-01-29 |
2022-01-29 |
Medical and Health Sciences |
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Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Epidemiology of Coronary Artery Disease among People with HIV in Rural sub-Saharan Africa
REFNo: HS267ES
Our over-arching goals are to demonstrate the extent to which coronary artery disease (CAD) burden may be greater among PLWH in rural Uganda, to discern which risk factors are responsible for this greater burden, and to propose a risk score and promising intervention targets to improve the health of this population.
Aim 1: Determine whether CAD is more prevalent and severe among PLWH than HIV-uninfected comparators in rural Uganda. We will complete coronary CT angiography in 600 participants and compare the prevalence and severity of CAD between PLWH and HIV uninfected comparators, before and after adjustment for traditional risk factors
Aim 2: Determine the extent to which the association between HIV infection and CAD is modified by sex and region. Within our cohort, we will test for effect modification by sex
Aim 3: Identify regional correlates of CAD, and develop a risk prediction score for the presence of CAD among PLWH in rural sub-Saharan Africa. We will collect data on traditional (e.g. age, smoking, diabetes), HIV-specific (e.g. macrophage activation, CD4 count, ART history), and region-specific factors (e.g. biomass exposure, K:T ratio, tuberculosis infection). In Aim 3a we will include traditional, HIV-specific and regional risk factors in models to identify correlates of CAD. In Aim 3b, we will propose a simplified risk score to identify PLWH with CAD.
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Uganda |
2019-01-29 |
2022-01-29 |
Medical and Health Sciences |
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Non-degree Award |
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Rachael MacLeod
ID:
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A prospective observational study of intraventricular haemorrhage (IVH) in a neonatal cohort in Uganda: The IVHU Study.
REFNo: HS299ES
Overall objective
To study the proportion of low birth weight (LBW) babies affected by IVH and to assess the severity of and risk factors for IVH and outcomes after IVH at Mbale Regional Referral Hospital in eastern Uganda over a 6-month period.
Specific objectives
In LBW neonates in a Ugandan population:
• Describe the proportion of babies affected by IVH.
• Describe the timing and severity of IVH.
• Describe the incidence of complications including ventriculomegaly and cerebellar involvement, as well as other pathologies such as periventricular white matter changes with and without cystic change (PVL).
• Determine the neonatal morbidities and neonatal mortality associated with IVH.
• Describe risk factors associated with IVH.
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UK |
2019-01-22 |
2022-01-22 |
Medical and Health Sciences |
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Non-degree Award |
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Timothy Wakabi Waiswa
ID:
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LINKAGE BETWEEN SCHISTOSOMA MANSONI INFECTION IN BABOONS AND HUMANS WITHIN FISHING VILLAGES OF KASESE AND RUBIRIZI DISTRICTS IN QUEEN ELIZABETH NATIONAL PARK
REFNo: HS293ES
i. establish prevalence of S. mansoni in baboons and humans living in the fishing villages and factors associated with the infection
ii. assess the knowledge and perception of people living in fishing villages in and around QENP on transmission of zoonotic Schistosomiasis
iii. determine the geospatial and genetic relationship between S. mansoni in baboons and humans in fishing villages in and around QENP
iv. assess feasibility of stakeholder-identified interventions for addressing Schistosomiasis within the fishing villages
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Uganda |
2019-01-22 |
2022-01-22 |
Medical and Health Sciences |
|
Degree Award |
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Ivan Kimuli Ronald
ID: UNCST-2019-R000577
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Viral load monitoring among HIV infected patients at Mulago Hospital: Perceived barriers and facilitators
REFNo: HS261ES
1. To describe the viral load cascade at the HIV clinic of Mulago National referral hospital
2. To explore the barriers to and facilitators of viral load monitoring among HIV-infected adults at Mulago Hospital
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Uganda |
2019-01-15 |
2022-01-15 |
Medical and Health Sciences |
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Non-degree Award |
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Florence Brisset-Foucault
ID:
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Registering and Identifying People in Uganda A Historical Approach
REFNo: SS210ES
Today, norms and practices of biometric identification are objects of global fascination, curiosity, anxiety or scrutiny. Yet, in the case of Africa, identification documents have hardly been central to scholarship. In order to fill this important gap, this study proposes to focus on the history of official/administrative documents of identification in Uganda, as objects of governmentality (Foucault, 2004). A great variety of identification documentation will be included, as empirical objects of study: birth certificates, voters’ cards, introduction letters by Local councils, party-membership cards, as well as other forms of nominative documentation such as land certificates and drivers’ licenses. The idea is that the daily uses of these objects and the popular representations attached to them will inform us on the parameters of public action, ordinary social life, the imagination of identities and civic cultures. By better understanding Ugandans' previous experiences of identification, it is expected that this research will inform best practices in terms of the documentation and verification of identities, and of the implication of these processes on the State and on society.
|
France |
2019-01-15 |
2022-01-15 |
Social Science and Humanities |
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Non-degree Award |
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Alex Maxwell
ID:
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'Post-conflict recovery in Gulu (North Ugandan Acholiland): Examining the impact of a decade of ex-combatant re-integration interventions on the coping strategies of communities, their social capital and the state of civil society.'
REFNo: SS243ES
This research aims to explore how viable ways of life are constituted by local communities in the North Ugandan post-conflict scenario. The post-Lord’s Resistance Army (LRA) peacebuilding project by the international community in Northern Uganda has resulted in no repeat of violence since the end of the conflict. However, there has been little effort to learn from the Ugandan experience concerning the critical conditions, which enables social repair to become possible following displacement by armed conflict. This research seeks to understand how displacement and return have affected social repair through the perceptions and understandings of the local people concerned. This contrasts with the focus from the perspective of ‘ex-combatants’ in the peacebuilding literature which analyses reintegration interventions. This research focuses on an under researched area: the role of the community in the post-conflict reintegration process. The research uses a case study approach (detailed by Yin, 1989) with a focus on life histories, to examine how local communities in Gulu, often referred to as the ‘recipients’ of international projects, have negotiated reintegration and social repair through their interactions with ex-combatants. Further, the research examines how external intervention has affected the Gulu communities’ own understandings of life after conflict within a ten year period (2008-present).
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UK |
2019-01-15 |
2022-01-15 |
Social Science and Humanities |
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Degree Award |
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BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
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PERFORMANCE EVALUATION OF POTENTIAL POINT-OF CARE RDTs FOR THE DIAGNOSIS OF PLASMODIUM FALCIPARUM WITH PFHRP-2 GENE DELETION AT VARYING MALARIA TRANSMISSION SETTINGS IN UGANDA
REFNo: HS282ES
1. To determine the sensitivity of a range of malaria rapid diagnostic tests using microscopy as gold standard under the varying malaria epidemiological settings in Uganda
2. To determine the specificity of a range of malaria rapid diagnostic tests using microscopy as gold standard under the varying malaria epidemiological settings in Uganda
3. To establish the positive and negative predictive value of a range of malaria rapid diagnostic tests under the varying malaria epidemiological settings in Uganda
4. To determine the prevalence and geographical location of P.falciparum parasites with pfhrp2 gene deletion
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Uganda |
2019-01-15 |
2022-01-15 |
Medical and Health Sciences |
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Non-degree Award |
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Gloria Odei Adobea
ID:
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Utility of mid-upper arm circumference in case detection, admission, monitoring treatment and referral of children 6-59 months with severe acute malnutrition in Karamoja: a retrospective analysis
REFNo: HS304ES
To assess the utility of MUAC as an indicator for case detection, admission, monitoring treatment and referral of children 6-59 months with SAM in Karamoja.
|
Ghana |
2019-01-15 |
2022-01-15 |
Medical and Health Sciences |
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Degree Award |
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Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
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COGNITIVE IMPAIRMENT AMONG PATIENTS WITH A FIRST EPISODE OF PSYCHOSIS IN UGANDA: ASSESSMENT, RISK PROFILE AND IMPACT ON QUALITY OF LIFE.
REFNo: HS142ES
1. To review the evidence on the assessment of cognitive function using brief neuropsychological tests in patients with FEP in sub Saharan Africa.
2. To determine the validity of cognitive assessments delivered using a smart phone application in patients with FEP in Uganda.
3. To determine mean duration and factors associated with resolution of psychotic symptoms among patients with FEP in Uganda.
4. To determine the association between genetic and environmental factors (childhood trauma and DUP), and the development of CI in patients with FEP in Uganda.
5. To determine the association between impairment in specific cognitive domains and quality of life in patients with FEP in Uganda.
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Uganda |
2019-01-08 |
2022-01-08 |
Medical and Health Sciences |
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Degree Award |
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Patrick Ogwok
ID:
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Mediators of dietary and physical activity behaviors among women of reproductive age in urban Uganda-Kampala.
REFNo: HS290ES
To understand factors explaining dietary behaviors among women of reproductive age (18 to 45 years) living in Kampala
To understand factors explaining physical activity behaviors among women of reproductive age (18 to 45 years) living in Kampala
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Uganda |
2019-01-08 |
2022-01-08 |
Medical and Health Sciences |
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Degree Award |
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Thereza Piloya Were
ID: UNCST-2019-R000491
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VITAMIN D STATUS; ASSOCIATED CLINICAL AND BIOCHEMICAL FACTORS AMONG CHILDREN INFECTED WITH HIV AT BAYLOR PAEDIATRIC CLINIC, KAMPALA UGANDA
REFNo: HS294ES
1. To determine the prevalence of vitamin D deficiency among HIV infected children and adolescents aged 6 months-12 years at Baylor Paediatric HIV Clinic, Kampala.
2. To determine the clinical and biochemical factors associated with vitamin D among HIV- infected children and adolescents.
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Uganda |
2019-01-08 |
2022-01-08 |
Medical and Health Sciences |
|
Non-degree Award |
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Simon Peter Kayondo
ID:
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PREVALENCE AND FACTORS ASSOCIATED WITH HEPATITIS B VIRUS INFECTION AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE CLINIC IN MULAGO HOSPITAL
REFNo: HS257ES
General objective
To determine the prevalence and factors associated with Hepatitis B Virus infection among pregnant women attending antenatal care clinic in Mulago Hospital.
Specific objective
1. To determine the prevalence of HBV infection among pregnant women, attending ANC clinic in Mulago Hospital.
2. To establish the factors associated with HBV infection, among pregnant women attending ANC clinic, in Mulago Hospital.
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Uganda |
2018-12-20 |
2021-12-20 |
Medical and Health Sciences |
|
Degree Award |
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Ben Jones
ID:
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Educating institutions: A study of the influence of educated young women and men on local politics in Uganda
REFNo: SS232ES
In the Teso region of eastern Uganda there is a generation of young men and women in their twenties and thirties who are the first in their family to go to school. I want to investigate the effect this generation is having on local institutions – school committees, church groups, village courts, burial societies. What are the political entailments of education? Does education open up new paths to becoming influential? Does it help to reconfigure gender relations? Do educated youth approach politics in new ways? Available research on education in the developing world focuses on its economic impact, or on the spread of modern attitudes, particularly among male urban youth. Less is understood about the political consequences of education, or about the transformations taking place with the arrival of educated young men and, more especially, women, in the countryside.
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UK |
2018-12-20 |
2021-12-20 |
Social Science and Humanities |
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Non-degree Award |
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Ellison McNutt
ID:
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Quantifying Foot Position During Quadrupedal Walking in Semi-Wild Chimpanzees
REFNo: NS65ES
The goal of this project is to be among the first studies to collect biomechanical walking data on a large number of individuals from semi-wild primates, including plantigrade and semi-digitigrade species to connect behavior to skeletal anatomy. Specifically in Uganda, to quantify/characterize the foot strike patterns in semi-wild chimpanzees throughout their gait cycle to assess its impact on their skeletal anatomy with implications for understand fossil primate locomotions.
|
USA |
2018-12-20 |
2021-12-20 |
Natural Sciences |
|
Degree Award |
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David Wells Arthur
ID:
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How the relatedness information encoded in scent changes with age in wild banded mongooses
REFNo: NS69ES
Determine how relatedness information is communicated and understand why synchronised births are sufficient to prevent infanticide.
Determine if juveniles encode the same relatedness information in scent that adults do.
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UK |
2018-12-20 |
2021-12-20 |
Natural Sciences |
|
Degree Award |
|
Joseph Akuze
ID:
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An Algorithm to Predict Newborn Complications in the First 28 days of Life at Iganga General and Jinja Regional Referral Hospital (N-COP Study)
REFNo: HS256ES
General Objective
The purpose of this study is to develop – an algorithm to predict newborn complications in order to improve management and care among newborns.
Specific Objectives
1.To develop an algorithm to predict newborn complications in the first 28 days of life stratified by gestation age at birth.
2.To determine the incidence of newborn complications within the first 28 days of life: -stratified by gestational age at birth.
3.To establish the time to newborn complications within the first 28 days stratified by gestational age at birth.
4.To estimate time to newborn complications and mortality within the first 28 days of life.
|
Uganda |
2018-12-20 |
2021-12-20 |
Medical and Health Sciences |
|
Non-degree Award |
|
Julia Downing
ID:
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Impact of the Ugandan Palliative Care Nurse Leadership Project
REFNo: HS274ES
The study is aimed at assessing the impact of the original Ugandan Palliative Care Nurse Leadership Programme
|
UK |
2018-12-20 |
2021-12-20 |
Medical and Health Sciences |
|
Non-degree Award |
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Jane Francis Namukasa Wanyama
ID:
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Antiretroviral therapy outcomes, barriers and facilitators of linkage into care and adherence among individuals initiating treatment under “Test and Start†guidelines in urban HIV clinics in Uganda
REFNo: HS281ES
General Objective: To establish treatment outcomes, barriers and facilitators of adherence and linkage to care among individuals initiating ART under “Test and Start†guidelines in six urban HIV clinics in Uganda.
Specific objectives: The study has three specific objectives:
Specific objective 1: To describe treatment outcomes among HIV positive individuals initiated on ART under “Test and Start†guidelines over a 2-year period.
This will be a retrospective evaluation of prospectively collected data of all HIV positive individuals who were initiated on ART under “Test and Start†guidelines at Kisenyi, Kisugu, Kawaala, Komamboga and Kiswa HC III. Our extracted dataset will include all eligible ART patients who started ART between January 2017 and January 2018. Follow up period for each participant will be two years until January 2020. We shall describe the proportion of participants achieving virological suppression, incidence of OIs, retention rates, mortality rates and adherence patterns for patients retained on ART at 6,12 and 24months.
Specific Objective 2: To explore barriers and facilitators for linkage into care following HIV diagnosis under “Test and Start†guidelines.
This will be a qualitative study in which a purposively selected sample of individuals who tested HIV positive but were not linked into care or those who were linked into care but declined to initiate ART will participate in In-depth interviews (IDIs). We shall also conduct IDIs to explore facilitators and barriers for linkage into care among those who were linked into care at any of the five Health Center(HC) IIIs following HIV diagnosis.
Specific Objective 3: To explore barriers and facilitators for adherence to ART among individuals initiated on ART under the “Test and Start†guidelines.
This will be a qualitative study in which a purposively selected sample of individuals initiated on ART under “Test and Start†guidelines will participate in IDIs. Adherence scores will be extracted from the ART clinic databases as assessed by the health care providers. We shall explore facilitators for ART adherence among adherers (reporting adherence ≥95%) with corresponding viral suppression as a proxy marker for adherence. To explore barriers for adherence, participants with poor adherence will be categorized as irregular (inconsistent) and lost to follow up (LTFU). Both adherers and non-adherers will be stratified by gender, marital status, employment status and age.
Additionally, Key Informant Interviews (KIIs) will be conducted with healthcare providers to assess their experiences regarding barriers and facilitators for ART adherence among patients initiated on ART under “Test and Start†guidelines.
|
Uganda |
2018-12-20 |
2021-12-20 |
Medical and Health Sciences |
|
Non-degree Award |
|
Anthony Fuller
ID:
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A Community-Based Cross-sectional Study of Epilepsy Prevalence and Barriers to Epilepsy Treatment in Uganda
REFNo: HS291ES
Main objective: The first objective of this study is to estimate the countrywide prevalence of epilepsy in Uganda. The second objective is to characterize the community-held beliefs and barriers affecting epilepsy treatment in Uganda.
Specific Objectives:
AIM 1: To estimate the countrywide prevalence of epilepsy in Uganda
1A- To describe geographic variation, if any, of epilepsy prevalence
AIM 2: To characterize the community-held beliefs about epilepsy in Uganda.
2A- To assess knowledge, attitudes, and other factors associated with epilepsy treatment barriers in Uganda.
|
USA |
2018-12-20 |
2021-12-20 |
Medical and Health Sciences |
|
Non-degree Award |
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