Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Stephen Kyakulumbye
ID:
A framework for developing citizen-centric e-government applications in developing contexts: The design-reality gap
REFNo: IS9ES

To document a feasible participatory design methodology for citizen e-government applications.
Uganda 2018-02-13 2021-02-13 Social Science and Humanities Degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
Steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily in the presence of rifampicin and isoniazid (Rifinah or the local generics)
REFNo: HS161ES

Primary Objective: To evaluate the steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic) Secondary Objectives: 1. To assess the safety and tolerability of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic) 2. To investigate the association between genetic polymorphisms in drug disposition genes and drug exposure.
Nigeria 2018-02-06 2021-02-06 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
A PHARMACOKINETIC EVALUATION OF ETONOGESTREL IMPLANT IN HIV-INFECTED WOMEN ON DARUNAVIR VERSUS RIPILVIRINE-BASED ANTIRETROVIRAL THERAPY (DRIVE-I)
REFNo: HS145ES

Primary objective: To compare the PK of ENG (68 mg) contraceptive implant over 6 months in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART versus historical controls Secondary objectives: (1) To predict the disposition of ENG over the subsequent 2.5 years of intended use through PK modeling of ENG concentrations beyond 12 months of use in HIV-infected women using DRV- or RPV-based ART (2) To describe the PK exposure over 12 months of ENG contraceptive implant in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART (3) To describe the pharmacokinetics of DRV 12 hours post-dose (C12) and RPV 24 hours post-dose (C24) prior to and during 12 months of combined use with ENG. (4) To describe the safety and tolerability of combined use of DRV/RTV or RPV and ENG during 12 months of combined use. (5) To describe the relationship between ENG concentrations and participant specific covariates including body weight, albumin, sex-hormone binding globulin and pharmacogenetic factors.
Nigeria 2018-01-29 2021-01-29 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
A PHARMACOKINETIC EVALUATION OF LEVONORGESTREL IMPLANT IN HIV-INFECTED WOMEN ON DARUNAVIR VERSUS RIPILVIRINE-BASED ANTIRETROVIRAL THERAPY (DRIVE-II)
REFNo: HS146ES

Primary objective: To compare the PK of LNG (150 mg) contraceptive implant over 6 months in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART versus historical controls. Secondary objectives: (1) To compare the PK of LNG over 12 months among women receiving DRV-based ART or RPV-based ART versus historical controls (2) To predict the disposition of LNG over the subsequent 4 years of intended use through PK modeling of LNG concentrations beyond 12 months of use in HIV-infected women using DRV- or RPV-based ART (3) To describe the pharmacokinetics of DRV 12 hours post-dose (C12) and RPV 24 hours post-dose (C24) prior to and during 12 months of combined use with LNG. (4) To describe the safety and tolerability of combined use of DRV/r or RPV and LNG during 12 months of combined use. (5) To describe the relationship between LNG concentrations and participant specific covariates including body weight, albumin, sex-hormone binding globulin and pharmacogenetic factors.
Nigeria 2018-01-29 2021-01-29 Medical and Health Sciences Non-degree Award
Charlotte Hawkins
ID:
The Anthropology of Smartphones and Smart Ageing
REFNo: SS141ES

This project will investigate fundamental changes in people’s relationship to age and health associated with the global rise of the smartphone. The aim is to combine an intellectual challenge in understanding the contemporary nature of age and the impact of new media, with an applied challenge to use this knowledge to help make mHealth (mobile health) interventions more effective. mHealth has potential both for helping those with limited access to professional care but also threatens to bypass and undermine professional medical services. Our aim is to complement technology-led mHealth interventions with ethnography-led participatory design, consisting of a three-way collaboration between mHealth professionals, our ethnographically informed team and our informants in the field. We aim to demonstrate how such collaborations can lead to more culturally appropriate mHealth interventions and more effective improvements in people’s lives.
UK 2018-01-29 2021-01-29 Social Science and Humanities Degree Award
Rose Gawaya
ID:
Challenges faced by women’s organisations in the AID space: Case studies in South Africa and Uganda
REFNo: SS90ES

The purpose of the research is to explore how women’s organisations access and utilise development aid. Access and utilisation of development aid impact on how women’s organisations achieve their organisational goals to address problems faced by women. The specific study objectives are to: 1.Determine how women’s organisations define and respond to the development aid space. 2.Identify what functions determine the participation of women in the development aid space. 3.Examine how access and utilisation of development aid contributes to feminist agendas.
Uganda 2018-01-16 2021-01-16 Social Science and Humanities Degree Award
Charles Okuonzi
ID:
Follower Voice Behavior and Leadership Competencies of Owner-managers in SMEs in Uganda
REFNo: SS142ES

The objective of thestudy is to establish the relationship between follower voice behaviour and leadership competencies of Ugandan SME owner-managers. The study is purely academic and shall involve owner-managers from 65 SMEs and 500 of their followers as respondents
Uganda 2018-01-11 2021-01-11 Social Science and Humanities Degree Award
Afra Nuwasiima
ID:
Incentives for Increased Access to Comprehensive Family Planning for Urban Youth Using a Benefits Card: A Pilot Study
REFNo: HS98ES

1) To evaluate the effectiveness of the FPBC program in increasing uptake of comprehensive family planning services among urban youth aged 18 to 30 years. 2) To evaluate the acceptability and usability of the FPBC program among the urban youth aged 18 to 30 years 3) To estimate the cost-effectiveness and potential budget impact of the FPBC program on the taxpayer. 4) To pilot test a corporate social responsibility financing model that will pay for and potentially sustain the FPBC program.
Uganda 2018-01-08 2021-01-08 Medical and Health Sciences Non-degree Award
Jeroen  Lorist
ID:
(Re-)ordering Meaning and Masculinities in Holland and Uganda: the Gender Transformative Approach
REFNo: SS127ES

For many years research and development interventions towards gender equality have focused on women and their empowerment. Recently discourse seems to have shifted to include the engagement of men and boys towards gender equality. Through multi-sited ethnography this project examines how the idea of the Gender Transformative Approach travels and is (re-)ordered between different nodes of a distributed knowledge network. Rutgers, a Dutch NGO, acts as a major node in this global knowledge network and is the main ethnographic site (i.e. organizational ethnography of the NGO in Holland). Other research sites are Uganda and Malawi, where Rutgers' development partners operationalise GTA through various development interventions. Objective of the study is to find out, through multi-sited ethnography, what the Gender Transformative Approach really does. Is the engagement of men for gender equality really changing gender relations to be more equal, as it claims it is, or is it old wine in new bottles as some within the women’s movement claim (i.e. is it doing more than women’s empowerment?). The study will also hold a critical development perspective and will critically look at any unintended effects of the interventions.
Netherlands 2018-01-08 2021-01-08 Social Science and Humanities Degree Award
Jennifer Driscoll Jane
ID:
Child Protection arrangements in sub-Saharan African states: a preliminary investigation into the interaction between informal child protection arrangements and formal intervention services and the effect of formal systems and agency interventions on indi
REFNo: SS94ES

a) preliminary investigations to gather the views of community leaders, local government officials, representatives of (I)NGOs, and (if possible) policy-makers from national government as to i) the key issues in relation to the protection of children at community level in Uganda; ii) particular challenges identified in relation to the interaction of formal child protection systems, community arrangements and (I)NGO interventions in the communities participating in the study; iii) examples of best practice and innovative work which has proven successful in promoting effective joint local arrangements in those communities; and b) to seek participants’ specific advice as to the focus and methods that should be employed in development of a larger bid and the geographical area of study (within sub-Saharan Africa).
UK 2017-12-20 2020-12-20 Social Science and Humanities Non-degree Award
Phoebe Donnelly
ID:
Gendered Decisions and Dynamics in Eastern Africa
REFNo: SS109ES

This research is for my PhD dissertation and potentially a book or articles. My central research question asks how the attitudes and behavior of non-state armed organizations (NSAOs) towards women and girls relate to the NSAO’s broad strategy. My framework will examine four aspects of gendered strategy: 1) the role women and girls fill within NSAOs; 2) whether NSAOs use forced marriage or other regulations of relationships as a strategy; 3) how the treatment of civilian women and girls, specifically the use of gender-based violence (GBV), relates to the objectives of the NSAO; and 4) how these organizations discuss gender in their external communications. My two case studies are al-Shabaab formed in Somalia and the Lord's Resistance Army in Uganda.
USA 2017-12-20 2020-12-20 Social Science and Humanities Degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
Dolutegravir in Pregnant HIV Mothers and their Neonates DolPHIN-2
REFNo: HS106ES

To evaluate dolutegravir (DTG) efficacy in late-presenting pregnant HIV-infected women
Nigeria 2017-12-20 2020-12-20 Medical and Health Sciences Non-degree Award
Jane Katusiime
ID:
A usable security model for mobile health systems in developing countries
REFNo: IS8ES

i. To investigate design and social technical challenges of mHealth systems in developing countries and determine requirements of a system that is usable by illiterate and semi-illiterate people. ii. To review and analyze the current security models and their suitability for usage in mobile health systems in developing countries iii. To design a hybrid security model that is usable in mobile health care systems in developing countries iv. To design and develop a tool that supports maternal health care and is also usable by illiterate and semi-illiterate people based on the hybrid model developed in (v). v. To evaluate the usability of the model based on the test utilization of the tool developed in vi by key stakeholders in maternal health.
Uganda 2017-12-20 2020-12-20 Social Science and Humanities Degree Award
Helen Byakwaga
ID: UNCST-2019-R001168
Understanding the HIV Care Provider Workforce in Africa
REFNo: HS138ES

1) Describe the sociodemographic and professional characteristics of health care workers providing HIV care as well as their perspectives, beliefs and attitudes towards practice. 2) Describe the kinetics of the HIV-dedicated health care workforce.
Uganda 2017-12-20 2020-12-20 Medical and Health Sciences Non-degree Award
Niina Marja Ahola Marja
ID:
Life After Return – Revisiting the Reintegration of Former Lord’s Resistance Army Abductees in Acholiland Region of Northern Uganda
REFNo: SS130ES

The key objective of this study is to increase knowledge on the reintegration process in post-conflict situations in general and the reintegration of former Lord’s Resistance Army (LRA) abductees in particular. This research gives voice to the former LRA abductees regarding their experiences of reintegration. The objective is to find out which factors have either promoted or prevented their process of integration back to society along the years, as it has been now a decade since the conflict in northern Uganda ended. Therefore, this study seeks to offer information on the challenges and successes that the former abductees have faced along their reintegration process, relying on their own experiences as the main source of data. In addition, one of the objectives of this study is to gather data for the investigator’s Master’s thesis.
Finland 2017-12-20 2020-12-20 Social Science and Humanities Degree Award
Matthew Sebastian Ryan
ID:
Youth, Humanitarianism, Security, and the Future in Northern Uganda
REFNo: SS131ES

The objective of this research is to better understand how the problematic positioning of young people in post-conflict settings affects prospects for peace-building as well as social integration more broadly. In so doing, it seeks to contribute to knowledge about how humanitarianism transforms in the aftermath of war and how young people navigate some of the myriad interventions which follow. In addition, it takes care to consider these concerns from the perspective of young people themselves, paying close attention to their own attempts to generate a livelihood in their contemporary lives.
USA 2017-12-20 2020-12-20 Social Science and Humanities Degree Award
Sara de Simone
ID:
Human security among South Sudanese self-settled refugees in Uganda: strategies of access to basic services
REFNo: SS138ES

The overall objective of the study is to investigate the perception of human security, particularly in its ‘freedom from want’ form, of refugees living in contexts characterised by resource scarcity and fragility through a specific case-study focusing on South Sudanese refugees in Ugandan West Nile province. The study will focus on the access basic services (education, health, water, sanitation) of the refugee population. Attention will be paid not only to the refugee population living in refugee settlements, but also to ‘self-settled’ refugees. The project will aim to assess: - (Self-settled) refugees’ strategies of interaction with the host community and local authorities; - The link between refugees’ perceptions of human security and local governance mechanisms.
Italy 2017-12-13 2020-12-13 Social Science and Humanities Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
Using Information Communication Technology (ICTs) to understand relationships between labour saving agriculture innovations, women’s time use and maternal and child nutrition outcomes in Uganda
REFNo: A24ES

1. To develop an innovative set of tools and metrics for measuring maternal time use and maternal and child dietary practices. 2. To assess the feasibility of using these tools - a computerised inter-active voice response (IVR) diary and a wearable camera - to assess women’s time use and maternal and infant dietary practices 3. To determine the concurrent criterion validity of these innovative methods via 15-hour direct observation; and compare it with traditional recall techniques 4. To describe and compare maternal time-use patterns, maternal and infant dietary practices and anthropometric status among women who are and who are not using labour saving technology for agriculture work 5. To examine associations between women’s time use in agriculture and maternal and infant dietary diversity and infant growth; and factors in the food environment that mediate food choice
Uganda 2017-12-13 2020-12-13 Agricultural Sciences Non-degree Award
Laura Schmucker
ID:
Piloting exercise: Evaluation of the impact of the ‘Solar Suitcase’ installation in healthcare facilities in Uganda on quality of care during labor and delivery and reliability of electricity.
REFNo: HS150ES

By conducting the pilot, we seek to gain a greater understanding of the nature of electricity reliability and deliveries in rural health facilities. The main objectives of the pilot include: 1) Obtain data on volume of deliveries, electricity failures, and baseline measures of quality of maternity care in order to run accurate power calculations for the upcoming research study 2) Test survey tools in the local context and refine the questions to gather data required for the upcoming research study 3) Test and validate light sensor equipment 4) Observe quality of work of field staff of various backgrounds to determine which qualifications and prior experience are best placed to collect data for the upcoming research study
USA 2017-12-13 2020-12-13 Medical and Health Sciences Non-degree Award
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
ESTIMATION AND EXPLANATIONS FOR THE HYPERTENSION SCREENING GAP AMONG HIV-INFECTED PATIENTS IN HIV PRIMARY CARE.
REFNo: HS118ES

1. Estimate the screening gap for hypertension among HIV-infected adults on ART attending Uganda Cares HIV primary care clinics in Masaka, Rakai and the St. Balikudembe Clinic in Kampala, Uganda over 12 months. 2. Document explanations for the screening gap for hypertension from the perspective of health providers at the Uganda Cares HIV primary care clinic in Masaka, Rakai and St. Balikudembe Clinic in Kampala, Uganda.
Uganda 2017-11-28 2020-11-28 Medical and Health Sciences Non-degree Award
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