Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Tiffany Basciano Nicole
ID:
No One Left Behind? A Study on the Human Rights of Women Living With HIV/AIDS in Uganda
REFNo: SS140ES

A study on adult women living with HIV/AIDS in Uganda. The study will include an examination of how women’s rights are integrated into HIV/AIDS-related laws, policies, programs, and initiatives in Uganda. We will further examine any challenges that women may face in family life, healthcare settings, or in the workplace because of their status, as well as any distinction in the experiences of women in urban versus rural settings. We hope that this research will help support the achievement of Sustainable Development Goals (SDGs) 3 – good health and well-being and 5 gender equality.
 USA 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Specioza  Twinamasiko
ID:
Oil discovery and compensation over land: Conceptualizing risks and vulnerabilities of women's household livelihoods i Albertine Graben, Uganda
REFNo: SS147ES

i- To discover the nature of oil related land contestations in the Albertine Graben. ii- To explore the risks and vulnerabilities experienced by women after oil discovery. iii- To examine land compensation processes before and after eviction. iv- To Explore the role of women in the land compensation process. v- To examine the strategies women have put in place to improve their livelihood.
Uganda 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Richard Wamimbi Wotti
ID:
Community Systems and Practices to Prevent and Respond to Violence Against Children in Uganda: Children's perceptions and lived experiences.
REFNo: SS158ES

1.Find out the perceptions and lived experiences of children most especially girls in preventing and responding to Violence Against Children in their communities. 2.Establish what the formal (education and social welfare) and non formal (family , faith based, traditional) approaches to child protection are and how they are being applied in creating safer communities in Uganda free from violence. 3.Examine how the formal and non-formal elements of community referral and reporting mechanisms are functioning to prevent and respond to Violence Against Children. 4.Explore how girls are affected by different forms of violence and how they are supported to enable them live in an environment that is free from all forms of violence throughout their life course
Uganda 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Wilfred Kokas Aupal Kokas
ID:
Change Management Practices and Performance of Selected Local Governments in Eastern Uganda
REFNo: SS165ES

1. To establish the relationship between executive support and performance of selected Local Governments in Eastern Uganda. 2. To assess the relationship between effective communication and performance of selected Local Governments in Eastern Uganda. 3. To investigate the relationship between employee involvement and performance of selected Local Governments in Eastern Uganda
Uganda 2018-04-24 2021-04-24 Social Science and Humanities Degree Award
Michael Carter Ross
ID:
Smallholder Farmers’ Returns and Learning from Subsidized Inputs in Uganda
REFNo: SS145ES

The Government of Uganda is launching an agricultural input subsidy program through an electronic voucher and we have the opportunity to study its first implementation phase (5,000 households) and provide lessons for scaling up the full program (450,000 households) by evaluating, inter alia, how different subsidy schemes affect the spread of technology to poor households and their networks and women farmers and their networks.
 USA 2018-04-20 2021-04-20 Social Science and Humanities Non-degree Award
Jacent Kamuntu  Asiimwe Kamuntu
ID:
BASELINE ASSESSMENT OF KNOWLEDGE, ATTITUDES AND PRACTICES ON HEALTH AND NUTRITION AMONG CAREGIVERS AND PREGNANT WOMEN IN LIVING GOODS OPERATIONAL DISTRICTS
REFNo: HS192ES

To assess and document existing knowledge, attitudes and practices of caregivers and pregnant women in Living Goods’ areas of operation on, nutrition and other health seeking behaviour during pregnancy as well as infant and young child feeding – (IYCF) practices.
 Uganda 2018-04-20 2021-04-20 Medical and Health Sciences Non-degree Award
Mael Leroux
ID:
Dual articulation in the communication system of chimpanzees
REFNo: NS47ES

The emergence of combinatoriality (phonology and syntax) in human language represents one of the key evolutionary transitions in life (Maynard Smith & Szathmary 1995). Despite its significance, we know very little regarding how unique this capacity is to humans or the evolutionary progression of this trait. By searching for core features of language, such as its combinatoriality, in the communication systems of closely related species to humans, particularly the primates, it is possible to shed light on whether the components of language are de novo evolved traits in humans or whether they have their origins rooted in the primate lineage. With this project, I aim to shed light on how unique combinatorics is to human language through empirically investigating the presence of linguistic forms of phonology and syntax in our closest living relative, the chimpanzee.
France 2018-04-20 2021-04-20 Natural Sciences Degree Award
JIMMY SSEMALULU
ID:
PRESCRIPTION PRACTICES AND USE OF LABORATORY PARAMETERS TO MONITOR EFFICACY AND TOXICITY OF ANTIRETROVIRAL THERAPY (ART) AMONG HIV PATIENTS (15YEARS AND ABOVE) AT ART CLINIC IN BUTABIKA NATIONAL PSYCHIATRIC REFERRAL HOSPITAL, UGANDA.
REFNo: HS151ES

STUDY OBJECTIVES General objective To assess prescription practices and use of laboratory parameters to monitor efficacy and toxicity of ART among HIV patients (15 years and above) at ART clinic in Butabika hospital. 1.5.2 Specific objectives 1. To describe pharmaceuticals prescribed for HIV patients (15 years and above) at ART clinic in Butabika hospital. 2. To determine drug drug interactions between ARVs and other medicines prescribed to HIV patients (15 years and above) at ART clinic in Butabika hospital. 3. To identify laboratory parameters used to monitor treatment response and toxicity of ARVs among HIV patients (15 years and above) on ART in Butabika hospital.
Uganda 2018-04-11 2021-04-11 Medical and Health Sciences Degree Award
Laura Bogart
ID:
GAME CHANGERS: A PILOT INTERVENTION TO EMPOWER HIV CLIENTS AS PREVENTION ADVOCATES IN UGANDA (PHASE 2)
REFNo: SS166ES

Primary objectives include: Assessing preliminary intervention effects on: a) protective behavior of the HIV-positive clients (condom use, partner concurrency/number of partners, engagement in HIV care, ART adherence) b) diffusion of prevention messages across the network, as assessed by the content and extent of communication with network members about protective behaviors (condom use, partner concurrency/number of partners, HIV testing, engagement in HIV care, circumcision), HIV disclosure, and HIV stigma
USA 2018-04-11 2021-04-11 Social Science and Humanities Non-degree Award
CHARLES LUGERO
ID:
A global registry to study the demographics, socioeconomic and clinical factors, etiologies, pathophysiology, management, barriers to care, and outcomes of heart failure patients
REFNo: HS144ES

Study 1. Estimate the incident rate of outcomes in HF patients in world Objectives regions and overall, and assess social and lifestyle factors (demographics, socioeconomic variables, clinical risk factors, diet, medication use, and health‐related quality of life), etiologies and variations in treatment patterns that might influence mortality and morbidity. 2. Describe determinants of different HF phenotypes (HFpEF, HFrEF, HF due to valvular disease, ALVD) in these world regions, and their management and outcomes. G‐CHF Protocol Page 3 2016‐09‐26 Version 1.2 3. Describe the potential role of biomarkers (BNP/NT‐proBNP and troponin, as available), related genetic determinants, and their relation to clinical factors, treatments, and type of HF 4. Assess non‐cardiac co‐morbidities at enrolment, their incidence during the study and how they influence outcomes from both cardiovascular and non‐cardiovascular mortality and morbidity. 5. In a sub‐study of approximately 4000‐5000 patients, perform measures of frailty, cognitive and lung function, mental health, adherence to medication, and dietary assessment, with collection of blood and urine samples for central analysis, to further understand the pathophysiologic changes in HF and their relation to outcomes. 6. Describe patient and system barriers to HF care in a global HF population.
Uganda 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
Clémence Bonneaud
ID:
Pant-hoot call in immature chimpanzees
REFNo: NS40ES

We will describe the age at which pant-hoot production starts. We will examine the order in which the four phases of the pant-hoot call develop. For example: is development sequential with the order of the final pant-hoot call, or do later phases (the climax) develop before early ones. We will investigate at what point multiple elements are produced within a call, and whether the sex differences seen in the pant-hoot calls of adults are also seen during development.
France 2018-04-04 2021-04-04 Natural Sciences Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Clinical and genetic factors influencing variability in warfarin dose requirements in Sub-Saharan African patients: An observational study
REFNo: HS164ES

1. To determine demographic and clinical factors that determine individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care 2. To identify ethnic-specific genetic factors influencing individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care
UK 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
Agnes Kiragga
ID:
Locating disengaged HIV positive women on Option B+ and ascertainment of outcomes among their infants
REFNo: HS175ES

1. To describe the pregnancy outcomes and HIV care status among women (and their exposed infants) who initiate Option B+ 2. To correct 6 week and 18 month estimates of MTCT through tracing of a random sample of HIV positive women who initiated Option B+ during pregnancy and disengaged from care. 3. To identify factors associated with HIV sero-positivity among infants born to women initiated on Option B+. 4. To establish the frequency of Multiclass Resistance among HIV positive infants born to women initiated on Option B+ 5. To estimate the proportion of disengaged women with viral failure and correct estimates of viral suppression (3 rd UN 90 goal) in the facilities.
 Uganda 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
ANNET MAGOLO KISAKA
ID:
INFLUENCE OF ORGANISATIONAL CULTURE ON EMPLOYEE PERFORMANCE IN PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS155ES

1. To examine the extent to which organizational mission influences employee performance in public Universities in Uganda 2.To assess the extent to which consistency affects employee performance in public Universities in Uganda 3. To establish how employee involvement influences performance in public universities
Uganda 2018-04-04 2021-04-04 Social Science and Humanities Degree Award
Erik Serrao
ID:
A Clinical Study to Validate the Accuracy and Usability of HemoTypeSCTM, Which is a Novel, Low-Cost, Rapid Diagnostic Test for Sickle Cell Disease
REFNo: HS158ES

The objective of this evaluation protocol is to determine the clinical accuracy of HemoTypeSC in diagnosing SCD-relevant Hb phenotypes (A/A, A/S, A/C, S/S, S/C, and C/C) as compared to “gold standard” HPLC/IEF laboratory testing methodology.
 USA 2018-03-27 2021-03-27 Medical and Health Sciences Non-degree Award
Richard Batamwita
ID:
Utilization of obulamu interventions by sex workers and men who have sex with men: a retrospective analysis of services delivery data.
REFNo: HS189ES

To determine changes in the levels of utilization of HIV and STI services by MSM and FSW before and after OBULAMU campaign in Uganda and to compare their utilisation levels with those of the general population (non-MSM and non-FSW population).
Uganda 2018-03-27 2021-03-27 Medical and Health Sciences Non-degree Award
CORDELIA MBOIJANA KATUREEBE
ID:
Developing and Validating a Pediatric and Adolescent HIV Testing Eligibility Screening Tool for Health Care Providers in Uganda
REFNo: HS155ES

General Objective 1) To develop, validate and field test a Pediatric and Adolescent HIV Testing Eligibility Screening Tool (PATEST) for use in outpatient departments within health facilities in Uganda Specific Objectives 1) To develop a Pediatric and Adolescent HIV Testing Eligibility Screening Tool (PATEST) for use in outpatient departments within health facilities in Uganda. 2) To determine the sensitivity, specificity, positive predictive value and negative predictive value of the PATEST among individuals aged 18 months to 19 years in selected study health facilities in Uganda. 3) To assess the perceptions and experiences of use of the PATETST among health care workers, caregivers and adolescents attending outpatient departments within selected study health facilities in Uganda.
Uganda 2018-03-15 2021-03-15 Medical and Health Sciences Non-degree Award
Joanne Corbin Nancy
ID:
Effects of armed conflict and displacement on men's socio-cultural and economic roles in northern Uganda
REFNo: SS119ES

• To examine the impact of armed conflict and internal displacement on men’s socio-cultural and economic roles in Northern Uganda. • To examine this phenomenon from subjective experiences. • To explore the adaptations that men have made to deal with any socio-cultural and economic impacts from armed conflict and internal displacement. • To disseminate the findings from this study in appropriate venues as recommended by Ugandan colleagues and produce an article on the results of this research.
USA 2018-03-14 2021-03-14 Social Science and Humanities Non-degree Award
Innocent Besigye Kabahena
ID: UNCST-2019-R001025
 Identifying gaps in screening, diagnosis, clinical practice guidelines and improving hypertension management in primary care facilities in Tororo District
REFNo: HS176ES

1. To identify the gaps in the health facility minimum requirements for successful screening, diagnosis and management of hypertension in Tororo district primary care facilities. 2. To establish the gap between hypertension management guidelines and clinical practice in Tororo district primary care facilities 3. To describe what needs to change for improved care of hypertension in primary care facilities in Tororo District.
Uganda 2018-03-14 2021-03-14 Medical and Health Sciences Non-degree Award
Julie  Nabweteme
ID:
A Post Mortem review of hospital-based suspected Hepatocellular cancer deaths in Uganda to examine the relationship with Schistosomiasis
REFNo: HS116ES

Primary: • To investigate the prevalence of schistosomiasis based on histopathology findings among suspected hepatocellular carcinoma cases. Secondary: • To validate the diagnosis of hepatocellular carcinoma (HCC) among cases of the larger study, which is defined by clinician’s suspicion of HCC and/or presence of liver masses on ultra sound scan with liver mass histopathology obtained at the time of autopsy. • To pathologically correlate the level of liver fibrosis due to schistosomiasis among the HCC deaths adjusting for geographical location and HIV co-infection.
Uganda 2018-03-12 2021-03-12 Medical and Health Sciences Non-degree Award
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