Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Victoria Nankabirwa
ID: UNCST-2021-R011871
Relaxation Intervention to Improve Newborn Growth and Maternal Well-being
REFNo: HS6916ES

To examine the effect of the APRB on maternal outcomes such as stress, anxiety and depression.,To evaluate the effect of the adapted APRB on infant outcomes such as growth, feeding and adverse events.,To develop and adapt an audiorecording promoting relaxation during breastfeeding (APRB) for use among postpartum mothers Uganda.,
Uganda 2026-01-19 15:24:38 2029-01-19 Medical and Health Sciences Clinical Trial Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
Assessing the bottlenecks for coverage of Essential Emergency and Critical Care in Uganda, Tanzania, Ethiopia, and South Africa
REFNo: HS6924ES

To determine the underlying causes and suggested solutions of these bottlenecks.,To determine the implementation bottlenecks for the provision of EECC in public hospitals in Uganda, Tanzania, Ethiopia and South Africa ,To investigate the bottlenecks, and their underlying determinants, for the provision of EECC in hospitals in Uganda, Tanzania, Ethiopia and South Africa,
UK 2026-01-19 13:39:06 2029-01-19 Medical and Health Sciences Non-degree Award
Ronald Bisegerwa
ID: UNCST-2022-R011022
CRICKET: Critical events in anaesthetised kids undergoing tracheal intubation – a prospective, multi-centre observational study
REFNo: HS6846ES

To determine the incidence of anaesthesia cases with critical events associated with endotracheal intubation requiring intervention from the start of anaesthesia until the discharge of the patient from the post-anaesthesia care unit or end of anaesthesia ,To assess the incidence of critical events related to tracheal intubation at all international study sites. Furthermore, the study will investigate the used intubation techniques and identify possible improvement measures to increase patient safety.,
Uganda 2026-01-19 13:37:45 2029-01-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charlotte Smith Alice
ID: UNCST-2025-R022981
Understanding Women’s Purchasing Decisions of Internet-Enabled Handsets In Uganda
REFNo: SS4755ES

1. How does women’s understanding and perception of existing internet-enabled handset features / point-of-sale (POS) offerings / marketing / communications compare with that intended by providers?
2. What are the key internet-enabled handset features / POS offerings that would most influence women to purchase one? What are the trade-offs that women would make (between these features/POS offerings) when purchasing an internet-enabled handset?
3. How could handset sellers best communicate and market these key internet-enabled handset features/POS offerings to women?

UK 2026-01-13 16:16:17 2029-01-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
ALEX TWINAMATSIKO
ID: UNCST-2025-R018945
CURRICULUM ADAPTATIONS FOR LEARNERS WITH INTELLECTUAL DISABILITY THAT REQUIRE LIMITED SUPPORT IN INCLUSIVE PRIMARY SCHOOLS IN UGANDA. A CASE OF ISINGIRO TOWN COUNCIL, ISINGIRO DISTRICT
REFNo: SS4608ES

1. To establish the aspects of curriculum adaptation used in teaching learners with intellectual disabilities that require limited support in inclusive primary schools in Isingiro Town Council, Isingiro District
2. To examine how the teachers, adapt curriculum for learners with intellectual disabilities that requires limited support in inclusive primary schools in Isingiro Town Council, Isingiro district
3. To analyse the challenges the teachers, experience in implementing curriculum adaptation practices for learners with intellectual disabilities that require limited support in inclusive primary schools in Isingiro Town Council, Isingiro district.

Uganda 2025-12-23 8:33:34 2028-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Bethan Mason Elaine
ID: UNCST-2024-R016027
Exploring the intestinal landscape of wild great apes
REFNo: NS1057ES

Characterise and compare the bacterial, bacteriophage and symbiotic eukaryote communities of humans, with varying levels of habitat overlap with chimpanzees, by conducting metagenomic sequencing and comparative analysis of identified OTUs, to investigate the extent and impact of so-called “humanisation” of the intestinal landscape amongst wild great apes existing within varying proximity of humans.Analyse the interactions, through OTU co-occurrence networks, between the different members of the intestinal landscape in both humans and non-human primates.Identify the symbiotic eukaryote and protozoan communities of the gastrointestinal tract of domestic animals exhibiting spatial overlap with eastern chimpanzees.Evaluate potential interspecies transmission of intestinal parasites between humans, domestic animals, and wild chimpanzees by comparing parasite diversity and genetic similarity of those occurring in share habitats.
UK 2025-12-22 17:13:19 2028-12-22 Natural Sciences Non-Clinical Trial Non-degree Award
Denis Collon Akwar
ID: UNCST-2025-R019046
Student Success in Online Academic Programs: A Case of Higher Education Institutions in Uganda
REFNo: SS4612ES

The study is intended to explore students’ success in online programs at higher education institutions in Uganda. It will be guided by the following research questions:
1. What factors impact students' success in online academic programs?
2. What is the effect of different pedagogical techniques on student success in online academic programs?
3. What perceptions do students and course instructors have on student success in online academic programs?
Uganda 2025-12-22 15:35:35 2028-12-22 Social Science and Humanities Non-Clinical Trial Degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
IMPACT OF THE TIMED AND TARGETED COUNSELLING (TTC) MODEL ON THE HEALTH AND NUTRITION OUTCOMES OF WOMEN OF REPRODUCTIVE AGE AND CHILDREN IN SELECTED REGIONS OF UGANDA
REFNo: HS6366ES

To determine the cost of implementing timed and targeted counselling (ttC) behaviour change mode.,To identify the key lessons learned so far to inform future programming initiatives. ,To establish the gender dynamics that influence health and nutrition outcomes in women and children.,To assess the extent to which communities accept improved health and nutrition practices among women and children.,To establish whether the model contributes to strengthened local and community health systems. ,To assess the extent to which the model interventions are influencing how women and their supporters are adopting household practices and behaviours that promote good health and nutrition outcomes.,To examine the Impact of the Timed and Targeted Counseling (ttC) Model on the health and nutrition outcomes in women of reproductive age and children 2 years old and above in Uganda.,
Uganda 2025-12-22 15:17:24 2028-12-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ATUHAIRE JUSTUS
ID: UNCST-2024-R004914
Exploring the Adoption and Utilization of Digital Health Technologies in Urban and Rural Healthcare Settings in Uganda: A Comparative Study
REFNo: HS6824ES

1.3 General Objective To assess the adoption and utilization of digital health technologies among healthcare providers in Uganda and identify the associated barriers and facilitators for digital health integration in Uganda. 1.3.1 Specific Objectives 1. To evaluate the extent to which healthcare providers in Uganda use digital health tools such as electronic health records (EHRs), telemedicine, clinical decision-support systems, and digital communication platforms in patient care. 2. To identify the barriers and facilitators for the adoption and utilization of digital health technologies in Uganda.
Uganda 2025-12-22 14:10:13 2028-12-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
Evidence-based Acceleration of Wasting Treatment Reform in Uganda for Revised IMAM Guideline Implementation Research - IMAM IR
REFNo: HS6917ES

1. To document the guideline review process, operational plan development and capacity building for implementation of the revised national wasting/IMAM guideline interventions 2. To establish the burden of child wasting and contextual factors of the intervention settings that may influence implementation of the wasting/IMAM interventions in Uganda 3. To determine the uptake and sustainability of implementing the revised IMAM interventions in the country healthcare system at facility and community levels 4. To establish stakeholders, data driven beneficiary and stakeholders’ mapping and in implementation of IMAM interventions 5. To establish the effectiveness of implementing the revised wasting/IMAM guideline interventions on program service outcome indicators at the district, regional and national levels
Uganda 2025-12-22 13:56:30 2028-12-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ROBERT SSEBUNYA
ID: UNCST-2021-R011585
Assessing the effectiveness of international human rights organizations in the promotion of political rights in Uganda. A case of Amnesty International
REFNo: SS4661ES

a) To analyse the obligation of Amnesty International in the promotion of political rights in Uganda
b) To assess the effectiveness of its advocacy strategies in the promotion of political rights in Uganda
c) To assess the role of amnesty international transformative education model in the promotion of political rights in Uganda

Uganda 2025-12-18 20:18:56 2028-12-18 Social Science and Humanities Non-Clinical Trial Degree Award
Anne Fitzpatrick Elizabeth
ID: UNCST-2024-R015774
Testing Community-led Outreach Clinics to Improve Health in Rural Areas
REFNo: SS3630ES

How do community-based outreaches affect ongoing health facility service delivery, and how can lessons from implementation science be used to improve health services in this population?,What impacts do community-based outreaches have on the labor force participation of adults aged 18 and older? ,How do community-based outreaches influence schooling outcomes for children aged 5-17? ,What is the effect of community-based outreaches on healthcare utilization and self-reported health outcomes? ,The objective of this study is to evaluate the effectiveness and cost-effectiveness of community-based outreaches on the health, educational, and labor market outcomes of households located more than 5km away from public health facilities. ,
USA 2025-12-18 20:14:54 2028-12-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
MURISHIDI KAMYA
ID: UNCST-2025-R016909
Relationship marketing and student satisfaction in private chartered universities kampala uganda
REFNo: SS4193ES

(i)To examine the effect of trust building on student satisfaction in private chartered universities in Kampala Uganda
(ii)To determine the effect of commitment on student satisfaction in private chartered universities in Kampala Uganda
(iii)To establish the effect of communication on student satisfaction in private chartered universities in Kampala Uganda
(iv)To examine the effect of loyalty programs on student satisfaction in private chartered universities in Kampala Uganda
(v)To assess the moderating effect of electronic marketing in the relationship between relationship marketing and student satisfaction in private chartered universities in Kampala Uganda.

Uganda 2025-12-18 20:06:37 2028-12-18 Social Science and Humanities Non-Clinical Trial Degree Award
Fredrick Masiga
ID: UNCST-2024-R004721
EFFECTIVENESS OF THE HEALTHCARE SYSTEM IN MANAGEMENT OF UNCOMPLICATED MALARIA AMONG CHILDREN IN MAYUGE DISTRICT, UGANDA
REFNo: HS6514ES

1.To determine treatment failure rates among children with uncomplicated malaria managed routinely at Kigandalo HC IV, Mayuge district.
2.To determine the factors associated with treatment failure among children managed for uncomplicated malaria at Kigandalo Health Centre IV, Mayuge district.
To explore the views and perspectives of health workers and patient caretakers on uncomplicated malaria treatment failures at Kigandalo Health Centre IV, Mayuge district.
Uganda 2025-12-18 20:02:57 2028-12-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Emmanuel Kiiza Mwesiga Kiiza
ID: UNCST-2019-R001588
A link between diet and cognitive function in Ugandan first-episode schizophrenia patients and healthy controls using nutrimetabolomics
REFNo: HS6783ES

3.To determine the effect of FES-specific DIBs generated from nine specific food groups on cognitive function.,2.To examine the modifying effect of non-genetic regulatory factors on dietary intake biomarkers generated in FES patients and healthy controls.,1.To compare dietary intake biomarkers generated from nine food groups in FES patients and healthy controls.,To utilize nutrimetabolomics to examine the link between diet and cognitive function in Ugandan first-episode schizophrenia patients and healthy controls.,
Uganda 2025-12-18 19:57:34 2028-12-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
Respiratory Morbidity of Schistosoma mansoni: Lung Function Abnormalities, Immunological Biomarkers, Radiological features, Respiratory Quality of Life, and Clinical Phenotypes
REFNo: HS6665ES

Main Objective
The overall objective is to determine and compare the nature and prevalence of
spirometric lung function abnormalities, respiratory symptoms, radiological features, and immunological biomarkers, and respiratory quality of life scores among people with and without Sm and derive clinical phenotypes of respiratory morbidity among people with Sm.

Specific Objectives
1. To determine and compare the nature and prevalence of spirometric lung function
abnormalities among people with and without Sm in Uganda

2. To determine and compare the respiratory symptoms, X-ray findings and immunological
biomarkers that are associated with lung function abnormalities among people with and
without Sm in Uganda.

3. To determine and compare the St. George Respiratory Questionnaire respiratory quality
of life scores and socio-demographic, clinical and immunological correlates among
people with and without Sm in Uganda.

4. To derive and validate clinical phenotypes of respiratory morbidity by cluster analysis of patients with Sm in Uganda.
Uganda 2025-12-18 19:08:42 2028-12-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Brenda Amaido Judith
ID: UNCST-2025-R022252
Peace in Pieces: Histories of Conflict, Peacebuilding and Women's Agency in Teso Sub Region
REFNo: SS4556ES

To investigate the conceptual contours of “peacebuilding” and how it resonates with women’s agency in Teso.

To examine how histories of conflict in Teso sub region interact to affect women’s inclusion in peacebuilding.

To interrogate women agency in conflict deflation and peacebuilding initiatives in pre-colonial Iteso community.

To analyse the evolving roles of women in peacebuilding initiatives in Teso.

Uganda 2025-12-18 19:02:28 2028-12-18 Social Science and Humanities Non-Clinical Trial Degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Evaluating the Feasibility of an AI-Powered Mobile Application for Mental Health Screening and Care in Uganda: A Digital Health Approach
REFNo: HS6700ES

1) To assess the perceptions of healthcare workers and the general public about the use of mobile applications for screening, self-help, referral and early detection of anxiety and depression in Uganda.
2) To develop an AI based mobile application for screening, self-help, referral and early detection of anxiety and depression in Uganda.
3) To assess the feasibility and acceptability of an AI based mobile application for screening, self-help, referral and early detection of anxiety and depression in Uganda.

Uganda 2025-12-18 18:57:13 2028-12-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eva Mirembe
ID: UNCST-2025-R021893
Enhancing Educator Support in eLearning in Higher Education Institutions through Learning Analytics
REFNo: SIR587ES

i. To elicit requirements for integrating the insights from LA into Educator support in eLearning ii. To design a LA based tool that can be used to enhance Educator support in eLearning iii. To evaluate the extent to which LA can enhance Educator support in eLearning
Uganda 2025-12-18 18:51:24 2028-12-18 Engineering and Technology Non-Clinical Trial Degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop
REFNo: HS6744ES

To explore if risk of progression differs between children who initially received 2 years of oral SAP as compared to 2 years of intramuscular SAP during the GOALIE trial. ,To determine in children with previously diagnosed mild RHD and echocardiographic stabilization after receiving SAP for at least 2 years, if stopping secondary antibiotic prophylaxis (SAP) is non-inferior to continuing SAP in preventing progression over the next 2 years. ,To determine in children with previously diagnosed mild RHD and echocardiographic normalization after receiving SAP for at least 2 years, if stopping SAP is non-inferior to continuing SAP for preventing progression over the next 2 years. ,To determine in children with previously diagnosed mild RHD and echocardiographic normalization or echocardiographic stability after receiving SAP for at least 2 years, if stopping SAP is non-inferior to continuing SAP for preventing progression by 4 years (2 years after SAP discontinuation). ,
Uganda 2025-12-18 18:47:07 2028-12-18 Medical and Health Sciences Clinical Trial Non-degree Award
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