Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
David Mafigiri Kaawa
ID: UNCST-2019-R001276
Testing on the frontline: empowering health engagement through ‘rational use’ of diagnostics for infectious and non-communicable disease (TIYENI Dx)
REFNo: SS5125ES

1. To define ‘rational use’ from the perspective of users, families, communities and frontline health workers and document social and structural drivers of self-testing for self-care under specific external conditions of stigma, emergency disease outbreaks and lifestyle and risk management for chronic disease across mainstream and marginalised groups.

2. To unpack the dynamic between empowerment through self-testing and engagement with public and private health services including the role of frontline health providers influencing self-testing in different contexts and potential for linkage to health and data systems.

3. To explore discourses of uncertainty, trust and risk influencing individual, family, community and frontline health worker decisions, embedded within complex socio-ecological environments and the impact of these on intended and unintended, beneficial and potentially harmful health and social consequences of self-testing.

4. To co-production of toolkits for ‘rational use’ of frontline diagnostics including community review of the UNICEF ‘Lets Test Toolkit’ and co-adaptation of self-testing generic and self-testing specific implementation guidelines and instructions for use.

5. To promote health equity across mainstream and marginalised groups in access to and ‘rational use’ of self-testing and monitoring that appropriately reflects future direct to consumer markets through a) informing country level strategies on frontline diagnostics as part of national health plans and b) developing a theoretical framework for people-centred ‘rational use’.

Uganda 2026-04-20 16:06:19 2029-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
John Mary Kanyamurwa
ID: UNCST-2025-R019398
Climate Change Threats to Livelihood Resilience and Adaptive Governance in Uganda's Bulambuli District
REFNo: SS5070ES

Major Objective To critically examine the impacts of climate change on livelihood resilience and adaptive governance in Uganda’s Bulambuli District, focusing on identifying targeted strategies to enhance rural communities' adaptive capacity and resilience to climate-induced shocks. Specific Objectives 1. To analyze the impacts of climate change on rural farm livelihoods and socio-economic stability in Bulambuli District. 2. To investigate the mechanisms by which governance system interventions address climate change challenges and enhance livelihood resilience. 3. To evaluate local communities' coping mechanisms in response to climate-induced challenges in Bulambuli District. 4. To identify gaps in governance mechanisms that hinder effective adaptation of rural communities' resilience to climate change impacts in the district.
Uganda 2026-04-20 16:02:15 2029-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
ROGERS NAMWIYIRI
ID: UNCST-2025-R018056
Lived Experiences of Out-of-School Adolescents in Kampala: A Qualitative Exploration of Drivers of Risky Sexual Behaviours, and Mitigation Counselling Strategies
REFNo: SS5119ES

1.To identify the lived experiences of out-of-school adolescents in relation to risky sexual behaviours
2.To describe the underlying drivers of risky sexual behaviours among out-of-school adolescents

3.To identify mitigation strategies for reducing risky sexual behaviours among out-of-school adolescents in Kampala
4.To analyse the effectiveness of counselling strategies tailored to reducing risky sexual behaviours among out-of-school adolescents.

Uganda 2026-04-20 15:57:51 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
Daphine Asiimwe
ID: UNCST-2025-R021246
MANAGEMENT INFORMATION SYSTEMS AND PERFORMANCE OF TOURISM INDUSTRY IN KAMPALA, UGANDA
REFNo: SS5120ES

Purpose
The purpose of this study is to examine the effect of management information systems on performance of the tourism industry in Kampala, Uganda.

Objectives
This study will be based on the following objectives;
1. To examine the effect of information management on performance of the tourism industry in Kampala, Uganda.
2. To examine the effect of customer relationship management on performance of the tourism industry in Kampala, Uganda.
3. To evaluate the effect of destination management on performance of the tourism industry in Kampala, Uganda.
4. To assess the moderating effect of operational efficiency in the relationship between management information systems and performance of the tourism industry in Kampala, Uganda.

Uganda 2026-04-20 15:55:56 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
John Othieno
ID: UNCST-2025-R020125
EXPANDING BRAIN TUMOR SEGMENTATION DATA TO CAPTURE AFRICAN POPULATIONS (BRATS-AFRICA)
REFNo: HS6328ES

1. To avail high-quality real-world imaging and clinical data carefully curated to preserve the heterogeneity in real world acquisition of clinical data and the inherent clinical presentation of brain tumors - a heterogenous disease with pathological features overlapping other noncancerous lesions in the brains.
3. To further expand BraTS-Africa project imaging datasets to include other brain tumor types (other than gliomas only), metastasis, and lesions such as stroke, multiple sclerosis, and epilepsy lesions from Uganda.

Uganda 2026-04-20 11:07:38 2029-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shango Patience  Jakheng Emmanuel
ID: UNCST-2025-R020526
WHOLE-GENOME CHARACTERIZATION AND PHYLOGENETIC ANALYSIS OF HUMAN PAPILLOMAVIRUS AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE AT ISHAKA ADVENTIST HOSPITAL, WESTERN UGANDA.
REFNo: HS7175ES

1. To determine the prevalence of HPV infection among pregnant women attending antenatal care at Ishaka Adventist Hospital. 2. To characterize the genotype distribution and genomic diversity of HPV strains circulating among pregnant women in this population. 3. To identify risk factors associated with HPV infection among pregnant women attending antenatal care at Ishaka Adventist Hospital. 4. To characterize HPV genomic integration patterns using whole-genome sequencing, stratified by HIV status and HPV phylogenetic clade. 5. To quantify E6/E7 oncogene expression using transcriptomic analysis and assess its relationship with HPV genomic status (integrated versus episomal). 6. To determine the phylogenetic relationships of HPV strains detected among pregnant women attending antenatal care at Ishaka Adventist Hospital.
Nigeria 2026-04-20 11:04:16 2029-04-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Gladys Angee
ID: UNCST-2025-R021927
Cost Management Practices, Operational Efficiency and Financial Performance of Agro-processing Firms in Acholi Sub-region
REFNo: SS5093ES

i. To establish the relationship between cost management practices and financial performance of agro-processing firms in Acholi sub-region. ii. To determine the correlation between cost management practices and operational efficiency of agro-processing firms in Acholi sub-region. iii. To establish the association between operational efficiency and financial performance of agro-processing firms in Acholi sub-region. iv. To find out the mediating role of operational efficiency on the influence of cost management practices on financial performance of agro-processing firms in Acholi sub-region v. To document the moderating role of firm characteristics on the relationship between cost management practices and financial performance of agro-processing firms in Acholi sub-region
Uganda 2026-04-20 11:00:51 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
Rupankar Dey
ID: UNCST-2026-R023803
People with Disabilities & Sexual Reproductive Health Citizenship in the Kalangala Islands of Lake Victoria, Uganda
REFNo: SS5105ES

This study aims to understand how the spatial context of the island shapes sexual reproductive citizenship surrounding sexuality norms, disability stigma, and social and environmental conditions in the Sese Islands of the Kalangala archipelago. Specific Objectives: This overarching aim is not explored through a single method. Instead, it is addressed through a set of interrelated objectives, each exploring a specific aspect of sexual and reproductive citizenship within island settings. The objectives focus on different groups and processes, allowing methods to be carefully matched to the sensitivities and experiences aimed to be explored. Objective 1 How does islandness shape experiences of gender-based violence (GBV) among people with diverse disabilities on the Kalangala Islands? Objective 2 How does islandness shape fishermen’s perspectives on gender-based violence (GBV)? Objective 3 What shapes access to SRH services for women with diverse disabilities? Objective 4 How does islandness shape the sexual reproductive citizenship of men with diverse disabilities?
India 2026-04-20 10:56:06 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
Fred Kigozi
ID: UNCST-2025-R021423
Postprandial effect of isocaloric challenge meals enriched with indigenous fruits and vegetables on glucose metabolism in individuals with type 2 diabetes in Wakiso District, Uganda.
REFNo: HS7347ES

General Objective To evaluate the postprandial effect of isocaloric challenge meals enriched with indigenous fruits and vegetables on glucose metabolism among people living with type 2 diabetes in Wakiso district, Uganda. Specific Objectives 1.To assess the acute postprandial effects of isocaloric challenge meals enriched with indigenous fruits and vegetables on incremental area under the curve (iAUC) blood glucose levels. 2.To assess the acute postprandial effects of isocaloric challenge meals enriched with indigenous fruits and vegetables on iAUC blood triglyceride levels.
Uganda 2026-04-20 10:47:24 2029-04-20 Medical and Health Sciences Clinical Trial Degree Award
Milton Ayoki
ID: UNCST-2026-R024563
From job displacement to economic resilience: Mapping the net impact of AI on formal and informal employment across three African economies
REFNo: SS5147ES

The overall objective of this study is to generate rigorous, gender-disaggregated, intersectional evidence on the net socio-economic impacts of AI on formal and informal employment in Uganda, Kenya, and South Africa, and translate this evidence into rights-based, African-led policy frameworks that ensure AI transitions are inclusive, safe, and aligned with sustainable development. Specific objectives (i) To measure the causal effect of firm-level AI adoption on net employment task recomposition, earnings volatility, and household poverty risk, disaggregated by gender, age, disability, geography, and formality status. Using a sequentially integrated design—linking 1,200 firms’ AI Intensity Index to 4,500 workers’ diary panel and administrative tax records—we will identify which demographic groups face displacement versus augmentation, and trace micro-to-macro transmission channels affecting social-protection demand. (ii) To identify, test, and refine policy levers—portable social protection benefits, mandatory algorithmic fairness audits, and gender-responsive re-skilling subsidies—that enhance economic resilience for vulnerable workers, particularly women, youth, and persons with disabilities. Through a participatory GEDI Lab (co-chaired with trade unions, women’s networks, and PWD advocates) with veto power over sampling, instruments, and recommendations, we will validate rights-based policy scenarios via a regulatory sandbox covering 20 digital-labour platforms. This ensures policies are not technocratic but reflect lived realities and African priorities, directly minimizing AI’s potential to exacerbate gender inequalities and human rights violations. (iii) To strengthen Africa’s AI-labour research ecosystem by mentoring eight African PhD students (≥60% women, ≥20% PWDs) through a triadic supervision model, and creating an open-source Continental Methodology Toolkit (AI Intensity Index calculator, AfroXLMR models, intersectional DiD estimators) for continent-wide replication. Outputs will be embedded in national AI strategies, ESG disclosure rules, and a COMESA Model Law on Algorithmic Labour Practices, ensuring sustainability beyond the project’s 36-month timeline and transforming global AI-labour debates from models that ignore Africa into African-led evidence that guides the continent’s digital future.
Uganda 2026-04-20 10:43:58 2029-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Emmanuel Wegoye
ID: UNCST-2024-R003214
Neurocognitive Outcomes and Changes in Brain and Cerebral Spinal Fluid (CSF) Volume after Treatment of Post-Infectious Hydrocephalus (PIH) in Ugandan Infants by Shunting versus Endoscopic Third Ventriculostomy/Choroid Plexus Cauterization (ETV/CPC)
REFNo: HS7254ES

We propose to: 1) Develop and empower CURE Children’s Hospital of Uganda as a unique hydrocephalus research center in the developing world 2) Test the hypothesis that ETV/CPC is superior to shunt-dependence in regard to treatment failure at 10 years; 3) Determine whether our initial finding of neurodevelopmental non-inferiority for ETV/CPC at 12 months is durable to the critical time of 10-years follow up; 4) Determine whether our initial finding of non-inferiority in brain growth for ETV/CPC at 12 months holds true at 10-years of follow up
Uganda 2026-04-15 22:23:51 2029-04-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Innocent Mwaka
ID: UNCST-2026-R023653
Action Research for the Gender for Development Uganda (G4DU) Programme
REFNo: SS4991ES

3. STUDY CONTEXT AND OBJECTIVES
Given the critical role of UNICEF in addressing gender imbalances in education, this multiyear action research aims at generating actionable evidence and fostering continuous learning for the enhancement of the G4DU Program’s financial support models and AEP. This iterative research will serve as a critical feedback loop, informing UNICEF's adaptive programming and policy advocacy efforts. The research will target students, headteachers, parents and district education departments. The study will be conducted over a period of 2-3 months annually , to allow for implementation of the intervention and observation of its effects. Being ongoing research, it will focus on the implementation phase of the programme from 2025-2028. The research will be conducted in four of the seven districts, namely: Yumbe, Adjumani, Lamwo, and Kitgum, focusing on selected schools and households .
Objectives of the action research:
1. To explore the effectiveness of newly developed and tested models of:
 Performance-based school grants for girls’ retention and completion of primary education.
 Cash transfer to households aiming at adolescent transitioning to and retention in secondary education.

2. To assess the effectiveness of the AEP model targeting out-of-school adolescents towards improving alternative access, accelerated pathways to primary education and transition into formal schools (primary and secondary schools).
3. To assess the relevance, efficiency, and sustainability of G4DU interventions in reducing barriers to education for vulnerable adolescent girls.
4. Determine the effect of school-level planning, local government capacity strengthening and community engagement, towards improving participation, retention and transition of girls.
5. Identify lessons learned from the implementation of financial support models and complementary activities and provide recommendations for programme adaptation and policy influencing.

The insights gained from these objectives will provide UNICEF and its partners with a robust evidence base to refine existing interventions, scale up successful approaches, and advocate for policies that institutionalise effective strategies for inclusive education in Uganda.

Uganda 2026-04-15 21:38:10 2029-04-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
Michael Timuzigu Kamugisha
ID:
Employability among University Graduates in Uganda
REFNo: SS5079ES

To examine the relationship between entrepreneurial alertness and employability. To establish the relationship between lifelong learning and employability. To investigate the relationship between entrepreneurial alertness and career adaptability. To establish the relationship between lifelong learning and career adaptability. To examine the relationship between career adaptability and employability. To investigate the mediating role of career adaptability in the relationship between entrepreneurial alertness and employability. To examine the mediation role of career adaptability in the relationship between lifelong learning and employability.
Uganda 2026-04-14 16:50:46 2029-04-14 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Kibira
ID: UNCST-2026-R023858
Measuring Prices, Availability & Affordability of Essential Sexual & Reproductive Health Commodities.
REFNo: HS7361ES

Main Objective 1. To generate reliable information on the price, availability and affordability of selected commodities in the SRH supply chain in Uganda, with the ultimate goal of improving access to affordable SRHCs to all. Specific Objectives 1. To assess the availability of Sexual and Reproductive Health Commodities among health facilities in the six major regions of Uganda 2. To determine the prices people pay for Sexual and Reproductive Health Commodities among Private health facilities in the six major regions of Uganda 3. To investigate the affordability of Sexual and Reproductive Health Commodities among Private health facilities in the six major regions of Uganda 4. To explore the main barriers of access to Sexual and Reproductive Health Commodities in the six major regions of Uganda.
Uganda 2026-04-14 16:47:17 2029-04-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Zachary kuloszewski
ID: UNCST-2026-R024610
The Impact of Labour Sharing on Workers’ Welfare and Growth of Small and Medium Enterprises in Urban Settings: Evidence from Uganda
REFNo: SS5081ES

1. Identify the labour market frictions and conditions which incentivize participation in labour sharing agreements/hiring from competitor firms.
a. Analyse the role of firm networks as an alternative screening mechanism for skilled workers and insurance mechanism against demand volatility
b. Investigate the ways in which firms structure these network arrangements to ensure incentive compatibility and reciprocity
2. Examine the relationship between labour sharing, firm productivity and growth and workers’ welfare outcomes
a. Examine the relationship between labour sharing and firm growth outcomes, including revenues, profits, employment levels, and assets
b. Examine the relationship between labour sharing networks and total worker earnings, skill acquisition, reservation wages, and aspirations
3. Make policy recommendations.
a. Compute the return on investment for hypothetical implementation of active labour market policies such as skill certification or subsidized search for firms
b. Give recommendations to inform policy to encourage hiring by SMEs.

USA 2026-04-14 16:45:21 2029-04-14 Social Science and Humanities Non-Clinical Trial Degree Award
AMANDA KISAAMO
ID: UNCST-2025-R022165
PREVALENCE, PATTERNS OF PRESENTATION AND FACTORS ASSOCIATED WITH NEURODEVELOPMENTAL DELAY AMONG CHILDREN AGED 2-59 MONTHS WITH CONGENITAL HEART DISEASE IN SOUTH WESTERN UGANDA.
REFNo: HS7389ES

• To determine the prevalence of neurodevelopmental delay in children aged 2–59 months with CHD in South Western Uganda.
• To describe patterns of presentation of neurodevelopmental delay in children aged 2–59months with CHD in South Western Uganda.
• To identify the factors associated with neurodevelopmental delay among children aged 2–59 months with CHD in South Western Uganda.

Uganda 2026-04-14 16:42:18 2029-04-14 Medical and Health Sciences Non-Clinical Trial Degree Award
RONALD WALOZI
ID: UNCST-2025-R021569
OPTIMIZATION OF THE CHEMICAL TREATMENT PROCESS FOR RICE HUSK-PINE SAWDUST HETEROGENEOUS BRIQUETTES TO IMPROVE COMBUSTION EFFICIENCY
REFNo: SIR635ES

This study aims to enhance combustion efficiency by optimizing the chemical treatment processes for heterogeneous briquettes using Response Surface Methodology.
The specific objectives of the study are:-
i. To formulate and characterize heterogeneous briquettes in different ratios of pine sawdust and rice husks to determine the one with the best efficiency
ii. To carry out chemical treatment on the identified heterogeneous briquettes using varying acid types and concentrations
iii. To investigate the effect of chemical treatment on the heterogeneous briquettes’ thermal, emission, mechanical, and chemical properties
iv. To optimize the chemical treatment process for the enhancement of combustion efficiency
v. To develop a combustion kinetics analytical model for heterogeneous briquettes
Uganda 2026-04-14 16:38:54 2029-04-14 Engineering and Technology Non-Clinical Trial Degree Award
Mugyenyi Edison
ID: UNCST-2026-R023282
INTEGRATION OF DISABILITY-RELATED COMPETENCES IN BACHELOR OF EDUCATION PROGRAMMES FOR STUDENT TEACHERS’ PROFICIENCY IN SELECTED UNIVERSITIES IN UGANDA
REFNo: SS4915ES

Purpose of the Study
The purpose of this mixed methods study is to assess the integration of disability-related competencies in Bachelor of Education programmes at selected universities in Uganda and to examine how this integration influences student teachers’ proficiency, with particular attention to the mediating roles of infrastructure and resources, as well as curriculum content and design, and the moderating effect of lecturer preparedness.
Objectives of the Study
1. To examine the relationship between the integration of disability-related competences and student teachers’ proficiency.
2. To explore how the availability and adequacy of infrastructure and resources mediate the relationship between the integration of disability-related competencies and student teachers’ proficiency.
3. To examine the extent to which curriculum content and design mediate the relationship between the integration of disability-related competencies and student teachers’ proficiency.
4. To evaluate the moderating effect of lecturer preparedness on the relationship between the integration of disability-related competences and student teachers’ proficiency.
5. To examine the combined influence of infrastructure and resources, as well as curriculum design and content, on student teachers’ proficiency in disability-related competencies.
6. To identify the challenges faced in integrating disability-related competences into Bachelor of Education programs.
7. To explore practical strategies for enhancing the proficiency of student teachers in disability related competencies.

Uganda 2026-04-14 16:35:09 2029-04-14 Social Science and Humanities Non-Clinical Trial Degree Award
Francis Ogwal Sabino Meri
ID: UNCST-2025-R016794
EVALUATION OF BIODIVERSITY OFFSET IMPLEMENTATION AND NET GAIN IN SELECTED LAKE VICTORIA RANGE NATURAL FORESTS IN UGANDA
REFNo: NS1060ES

1. To examine the policy and regulatory framework that underpin biodiversity offset design and implementation.

2. To examine the criteria considered in the design and implementation of biodiversity offset for the power transmission lines in Gangu and Mabira forest reserves

3. To evaluate net gain of the biodiversity offset for the power transmission lines in Gangu and Mabira natural forest reserves

Uganda 2026-04-14 16:33:10 2029-04-14 Natural Sciences Non-Clinical Trial Degree Award
Francis Matovu
ID: UNCST-2026-R023956
Community Participation and Sustainability of Government Program in Uganda. A case of Youth livelihood program in Kiboga District.
REFNo: SS5123ES

To examine how program design can influence sustainability of youth livelihood program in Kiboga District

To examine the relationship between program implementation and sustainability of youth livelihood program in Kiboga District.

To analyze the relationship between program monitoring and evaluation and sustainability of youth livelihood program in Kiboga District.

To evaluate the mediating effect of government policy on the relationship between community participation and sustainability of government programs
Uganda 2026-04-14 15:52:14 2029-04-14 Social Science and Humanities Non-Clinical Trial Degree Award
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