Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 6,046
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Soofia Mahmood
ID: UNCST-2025-R022700
DATA-DRIVEN TARGETING AND ADAPTATIONS FOR SCALING ULTRA POVERTY GRADUATION (UPG) IN MID WEST AND SOUTH WESTERN UGANDA
REFNo: SS5421ES

1. To assess whether data-informed prioritization of vulnerable households for individual coaching check-ins improves practice adoption and household economic outcomes. 2. To compare group enterprise investment and individual lending models in building sustainable for women-led Village Savings and Loan Associations (VSLAs) and improving economic outcomes for members. 3. To evaluate whether government staff can deliver household coaching with effectiveness compared to RTV staff when using the same tools and implementation approach.
Canada 2026-06-12 3:42:23 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Elisabeth Gerwing-Adima
ID: UNCST-2026-R025356
Determining the Burden and Drivers of Stigma and Mental Health Among Individuals with Lived Experience of Leprosy in Uganda.
REFNo: HS7717ES

General objective
The general objective of this study is to determine the burden and the drivers of mental health burden and stigmatization of those affected by leprosy in Uganda, to inform policy makers and enable effective intervention development. Specific objectives:1. To assess the mental health burden among people affected by leprosy in Uganda, by investigating both the burden of the mental distress (quantitative) and the lived experiences of patients (qualitative).
2. To determine the burden of leprosy-related stigmatization in the Mayuge district, Uganda (quantitative), and explore in-depth how leprosy stigmatization is experienced (qualitative).


Germany 2026-06-12 3:40:43 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Nabayinda
ID: UNCST-2026-R023998
Examining the intersection of climate change and Intimate partner violence among young women living with HIV
REFNo: SS5395ES

General Objective: The overall objective of the study is to examine how climate-induced disasters interact with IPV, poverty and mental health to influence ART adherence among YWLHIV in Eastern Uganda. Specific Objectives: 1) To Quantitatively assess the extent to which poverty and mental health mediate the relationship between climate-induced disasters and IPV among YWLHIV in Eastern Uganda; 2) Qualitatively explore young women’s lived experiences and stake holders perspectives of how climate-induced disruptions (e.g., disasters, resource scarcity) affect access to HIV treatment and adherence.
Uganda 2026-06-12 17:17:32 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sheila Bamweyana
ID: UNCST-2026-R024037
HPTN 104: A multisite, open-label, randomized crossover study comparing adherence to a single daily dual prevention pill (DPP) versus FTC/TDF and Combined Oral Contraception separate pill dosing (2PR), given for pre-exposure prophylaxis and pregnancy prevention in women.
REFNo: HS7679ES

Primary Objective(s):
-Compare PrEP adherence to the DPP versus 2PR during a randomized crossover period.


Secondary Objectives:
-Compare PrEP adherence to the DPP versus 2PR during a Choice period.

-Evaluate acceptability of DPP versus 2PR during crossover and Choice periods.

-Evaluate preferences for the DPP versus 2PR.

-Compare PrEP persistence on the DPP versus 2PR during the Choice period.

-Compare the tolerability, side effects and unintended consequences (e.g., Intimate Partner Violence [IPV], pregnancy, HIV) of DPP versus 2PR: overall, during crossover and Choice periods.


Exploratory Objective:
-Examine facilitators and barriers of DPP adherence, acceptability, and persistence, during the crossover period and during Choice periods.

-Use mathematical modeling to estimate the effectiveness of the DPP and 2PR in reducing HIV incidence within the study cohort during the crossover and Choice periods.


Uganda 2026-06-12 17:15:26 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Musiime -
ID: UNCST-2021-R013794
The AWARE-Kampala Study (Air Pollution and Well-Being: Assessing Risks and Enhancing Education among adolescents in Kampala)
REFNo: SS5260ES

The overarching objective is to understand knowledge, attitudes, and perceptions of air pollution and health among adolescents in Kampala using focus group discussions grounded in the Health Belief Model.
Uganda 2026-06-12 17:08:59 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frances Imokol
ID: UNCST-2026-R024413
Longitudinal Study on Teacher and School Leader Self-Efficacy in support of VVOB Uganda’s Learning Entrepreneurship and Agriculture Practically (LEAP) initiative.
REFNo: A768ES

The Green LEAP longitudinal studies have been designed to generate robust insights into how teachers’ and school leaders’ self-efficacy evolves through both pre-service and in-service training.
Uganda 2026-06-12 17:01:04 2029-06-12 Agricultural Sciences Non-Clinical Trial Non-degree Award
Jolly Magulu
ID: UNCST-2021-R013833
Community Mental Health and the Role of Village Health Teams in Uganda: Challenges, Intervention Acceptability, and Sustainability in Mukono District: A Case Study of Omni Med Uganda
REFNo: HS7449ES

1. To find out the challenges faced by VHTs in delivering community mental health services in Mukono District.
2. To understand community members’ and VHTs’ perceptions regarding the role of VHTs in providing psychosocial support services in Mukono District.
3. To describe community members' and VHTs’ perspectives on the acceptability, feasibility, and relevance of the SEEK-GSP intervention in Mukono District.
4. To understand the perceived implications of USAID’s withdrawal of funding on the sustainability and continuity of community mental health interventions in Uganda.

Uganda 2026-06-12 16:59:26 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maren Mickeler Alana
ID: UNCST-2024-R003691
Generative AI in Knowledge Work: Experimental Evidence from Uganda
REFNo: SS5275ES

1. Causally identify how GenAI adoption changes knowledge work, focusing on workplace interactions and productivity, 1.1. Estimate the effect of GenAI on individual task performance (e.g., speed, quality, accuracy), 1.2. Estimate the effect of GenAI on interactions with colleagues and supervisors when executing knowledge-intensive tasks (volume, information exchange, quality of interactions), 1.3. Assess broader organizational implications, including firm-level productivity and supervisory load.
Germany 2026-06-12 16:57:06 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine Katusiime
ID: UNCST-2026-R024829
Knowledge, Attitudes and Prevention Practices Among Parents of Children with Rheumatic Heart Disease at Uganda Heart Institute.
REFNo: HS7675ES

1.To assess the level of knowledge of parents of children with Rheumatic Heart Disease at Uganda Heart Institute.
2.To assess the attitudes of parents of children with Rheumatic Heart Disease at Uganda Heart Institute.
3.To determine the preventive practices undertaken by parents of children with Rheumatic Heart Disease at Uganda Heart Institute.
4.To determine the relationship between knowledge, attitudes, and preventive practices of parents of children with Rheumatic Heart Disease at Uganda Heart Institute.

Uganda 2026-06-12 16:55:39 2029-06-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Richard Ssewakiryanga
ID: UNCST-2026-R023427
PSP ACTION-RESEARCH ON ‘REPRESENTATION, NEGOTIATION AND SOCIAL DIALOGUE IN THE INFORMAL ECONOMY’
REFNo: SS5206ES

a) To document the formal or informal practices related to representation in social dialogue and other forms of structured negotiations are currently present in the hospitality sector in Uganda.
b) To understand in what ways workers in informal employment engage in other/alternative forms of organising and negotiations to improve their working conditions.
c) To document the role of development partners in organizing and enhancing unions’ capacities to integrate and address informal workers’ issues.
d) To analyse the extent to which studies and other forms of evidence impact social dialogues and actors in the tourism and hospitality sectors.

Uganda 2026-06-12 16:49:53 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Edna Tindimwebwa Brenda
ID:
PREVALENCE AND RISK FACTORS OF HYPERTENSION AMONG HEALTH CARE WORKERS IN SHEEMA DISTRICT, UGANDA
REFNo: HS7685ES

General Objective
To determine the prevalence and risk factors of hypertension among health care workers in Sheema district, Uganda.

Specific Objectives
1. To establish the prevalence of hypertension among health care workers in Sheema district.
2. To determine the factors associated with hypertension among health care workers in Sheema District.
Uganda 2026-06-12 16:39:33 2029-06-12 Medical and Health Sciences Non-Clinical Trial Degree Award
JESCA AKELLO OTAI
ID: UNCST-2025-R018523
ENTREPRENEURIAL INCOME ON THE GROWTH OF SMALL AND MEDIUM ENTERPRISES IN SOROTI DISTRICT, EASTERN UGANDA
REFNo: SS4774ES

Specific Objectives

1.To assess the effect of earned income on the growth of SMEs in Soroti District, Eastern Uganda.
2.To determine the influence of passive income on the growth of SMEs in Soroti District, Eastern Uganda.
3.To assess the influence of portfolio income on SMEs’ growth in Soroti District, Eastern Uganda.
4.To examine the moderating effect of the taxation system on the relationship between entrepreneurial income and the growth of SMEs in Soroti District.

Uganda 2026-06-12 16:37:52 2029-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Julian Bagyendera Kobutungi
ID:
Sustainable Development Goals Partnership: Endline Evaluation
REFNo: SS5435ES

3. Results, conclusions, and recommendations from the evaluation will be utilised at the programme and project level, as well as to inform future programming and policymaking.,2. Regarding accountability, RVO wishes to assess whether the SDGP has been a relevant, effective and (cost-)efficient instrument in contributing to sustainable impact on the relevant Sustainable Development Goals (SDGs).,1. To provide insights and evidence of the approaches and strategies applied by the SDGP. ,
Uganda 2026-06-12 16:34:16 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Felix Nabusamu
ID: UNCST-2025-R021280
Influence of Postharvest Handling Innovations on Losses in Maize among Smallholder Farmers in Eastern Uganda, the case of Bulambuli and Kween Districts
REFNo: A692ES

1. To analyze the PHH innovations by smallholder maize farmers in Bulambuli and Kween Districts. 2. To examine the influence of PHH innovations on the quality of maize among smallholder farmers in Bulambuli and Kween Districts. 3. To assess the factors driving the PHH innovations among smallholder maize farmers in Bulambuli and Kween Districts.
Uganda 2026-06-12 16:28:49 2029-06-12 Agricultural Sciences Non-Clinical Trial Degree Award
Wietse Tol
ID: UNCST-2021-R013085
Examining how brief psychosocial programs can be integrated with livelihoods programs
REFNo: HS7548ES

To examine how brief psychosocial programs can be integrated with livelihoods programs, and to explore strategies and recommendations for how this could be achieved
Netherlands 2026-06-12 16:15:48 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
Rethinking the Use of Race, Ethnicity, and Ancestry in Genomics: Including Global Voices
REFNo: HS7222ES

1.To explore the perspectives of genome scientists and study participants from within the African continent on: (i) the use of population descriptors in genomics; and (ii) the risks and potential benefits of genomic research.

2.To determine and assess participants and researchers’ views on the use of population descriptors in genomics, the risks, and potential benefits of genomic research
Uganda 2026-06-12 16:02:49 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Deogratius Ssemwanga
ID: UNCST-2025-R021563
Mpox Genomic Characterization, Viral Evolution and Host Response in Uganda: A multi-Omics Investigation of Transmission, Immune Evasion and Disease Severity
REFNo: HS7619ES

Main Objective:
To characterize the genomic, transcriptomic, epigenomic and proteomic profiles of MPXV infection in symptomatic cases and their contacts to inform improved diagnostic, control and management strategies.
Specific Objectives:
Objective 1: Viral Evolution and Transmission of the MPXV. This objective seeks to characterize MPXV genomic diversity and identify mutations associated with viral load, transmission clustering and infection duration. This involves identifying genetic variants driving adaptation, transmission and pathogenesis, sequencing viral genome for real-time evolution tracking, defining transmission dynamics among Mpox cases and their contacts, and collecting data on transmission risk factors for improved transmission control.
Objective 2: Host transcriptional Expression. We’ll identify host gene expression signatures associated with Mpox severity, immune evasion, clearance, and progression by comparing cases, contacts, and healthy controls (HCs). HCs will provide baseline host gene expression profiles.
Objective 3: Epigenetic regulation. Assess whether MPXV infection alters chromatin accessibility and interferon-stimulated gene regulation in infected individuals. Host chromatin architecture and epigenetic markers in both asymptomatic and symptomatic Mpox infections will be defined enabling us to dissect and understand chromatin remodeling mechanism driving infection and disease progression.
Objective 4: Comparative Proteomic Analysis. To characterize proteomic signatures in Mpox suspected patients, close contacts, and healthy controls, leading to identification of potential biomarkers for infection detection and an understanding of host response in Mpox.
Objective 5: Integrated Multi-Omics Analysis. Integrate viral genomics, transcriptomics, proteomics and epigenomics to identify mechanisms of immune evasion and predictors of transmission success.
Objective 6: Living with Mpox Experience. To explore healthcare workers' and survivors' perspectives on the impact of Mpox diagnosis and management on physical, emotional, and social well-being in Uganda.

Uganda 2026-06-11 13:36:41 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANGELLINE KISAAKYE
ID: UNCST-2026-R023482
INFLUENCE OF GENDER ROLES ON FOOD AVAILABILITY AND ACCESSIBILITY IN KAABONG DISTRICT, UGANDA.
REFNo: SS5216ES

(i) To establish the gender roles terrain in the context of food security in Kaabong West Sub-county, Kaabong district.
(ii) To investigate the influence of gender roles on food availability in Kaabong West sub-county, Kaabong district.
(iii) To analyse how gender roles shape patterns of food accessibility in Kaabong West sub-county, Kaabong district.
(iv) To examine strategies for mitigating gender-based vulnerabilities to enhance food security in Kaabong West sub-county, Kaabong district.

Uganda 2026-06-11 13:35:07 2029-06-11 Social Science and Humanities Non-Clinical Trial Degree Award
Michael Byamukama
ID:
Modelling HIV/AIDS Transmission in the Era of Biomedical Prevention: A Policy Oriented Mathematical Approach
REFNo: NS1268ES

1. To develop a deterministic compartmental model incorporating HIV progression and biomedical interventions (ART, PrEP, PEP).
2. To compute and analyse the effective reproduction number under various intervention scenarios.
3. To estimate model parameters using national data, conduct sensitivity and uncertainty analyses in order to determine impactful parameters.
4. To simulate realistic intervention scenarios and project long-term outcomes in prevalence and incidence.
Uganda 2026-06-11 13:31:21 2029-06-11 Natural Sciences Non-Clinical Trial Non-degree Award
Joseph Rujumba Rujumba
ID: UNCST-2022-R011160
Post-Discharge Malaria Chemoprevention (PDMC) in Children with Severe Acute Malnutrition (SAM): A Qualitative Study of Acceptability and Use in Malawi and Uganda
REFNo: HS7633ES

1. To explore health workers’ and caregivers’ initial perceptions, knowledge, and attitudes towards PDMC-SAM before full implementation (prospective phase).
2. To examine the experiences of health workers and caregivers during trial implementation, including perceived benefits, burdens, and challenges of PDMC-SAM (retrospective phase).
3. To assess health workers’ and caregivers’ reflections after trial completion regarding the acceptability, feasibility, and sustainability of PDMC-SAM, and to identify anticipated adaptations required for scale-up (retrospective phase)

Uganda 2026-06-11 13:27:59 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."