Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
CHRISTINE JOYCE ANGIMA
ID: UNCST-2025-R022785
EFFICACY AND ACCEPTABILITY OF PSYCHOTHERAPY INTERVENTION AND SELF-ESTEEM AMONG PREGNANT ADOLESCENTS: A CASE OF KATAKWI DISTRICT GENERAL HOSPITAL
REFNo: SS5028ES

General Objective: To assess the efficacy and acceptability of psychotherapy interventions in improving self-esteem among pregnant adolescents attending Katakwi District General Hospital in Uganda. Specific Objectives: 1. To determine the level of self-esteem among pregnant adolescents attending Katakwi District General Hospital. 2. To assess the effectiveness of psychotherapy interventions in improving self-esteem among pregnant adolescents. 3. To examine the acceptability of psychotherapy interventions among pregnant adolescents receiving care at Katakwi District General Hospital.
Uganda 2026-04-02 17:43:08 2029-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Matthias Miti
ID: UNCST-2025-R021994
Gendered Effects of Land Documentation on Agricultural Livelihoods in Busoga Sub-Region
REFNo: SS4812ES

i. To establish the nature of gender disparities in the ownership of documented land in Busoga sub-region ii. To investigate the socio-cultural barriers that limit women’s ownership of documented land for agricultural livelihoods in Busoga sub-region iii. To assess how land documentation influences agricultural livelihoods differently for women and men in Busoga sub-region.
Uganda 2026-04-02 17:41:54 2029-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
Modeling the Economic Benefit of Low-Cost Laparoscopic vs. Open Surgery for Chest and Abdominal Cancers in Uganda
REFNo: HS6245ES

Aim 2: Measure the economic outcomes of laparoscopic surgery using KeyScope versus the standard of care (open surgery or open biopsy), including pre- and post-operative costs, among a simulated cohort of patients with cancer needing biopsy or resection.,Aim 1: Measure the risk of CHE and impoverishment due to medical and non-medical costs among individuals seeking surgical care for cancers in the chest and abdomen at the Uganda Cancer Institute.,
Uganda 2026-04-02 17:39:02 2029-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Thomas Buyinza
ID: UNCST-2025-R016827
MINIMIZING AFLATOXIN CONTAMINATION IN MAIZE ACROSS THE SUPPLY CHAIN THROUGH FARMER–LED PARTICIPATORY TRAINING IN KAMULI, EASTERN UGANDA: A PILOT RANDOMIZED CONTROLLED TRIAL
REFNo: A743ES

General Objective: To evaluate the effectiveness of farmer-led participatory training in improving farmers’ knowledge, attitudes, and practices and reducing aflatoxin contamination in maize across the supply chain in Kamuli District, Eastern Uganda.

Specific Objectives
i. To enhance farmers’ knowledge, attitudes, and practices on Aflatoxin contamination and its health risks in Kamuli District, Uganda.
ii. To minimize Aflatoxin levels in maize to within acceptable limits set by the Uganda National Bureau of Standards in Kamuli District, Uganda.

Uganda 2026-04-02 17:36:12 2029-04-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Doreen Nakagaayi
ID: UNCST-2023-R006587
Assessment of a Novel Dual-Screen Model for Rheumatic Heart Disease Diagnosis: A Diagnostic Accuracy Study
REFNo: HS7123ES

To assess the inter-rater reliability between the two ADUNU-trained non-expert providers within the dual-provider diagnostic model, and to evaluate factors associated with discordant interpretations. ,To optimize the diagnostic performance of the dual-provider diagnostic model by using a receiver operating curve to identify optimal cutoff values for mitral and aortic regurgitation jet lengths that maximize its sensitivity and specificity for RHD diagnosis.,Secondary Aims To compare the diagnostic performance (sensitivity, specificity, and overall accuracy) among three distinct echo models and the current diagnostic gold standard. ,Primary Aim To determine the diagnostic performance (sensitivity, specificity, and overall accuracy) of the dual-provider diagnostic model compared to the current diagnostic gold standard of expert clinician interpretation using a fully functional echocardiography machine and comprehensive diagnostic protocol.,
Uganda 2026-04-02 17:34:59 2029-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Musiime -
ID: UNCST-2021-R013794
Experiences of caregivers and healthcare providers regarding post-discharge mortality and health-seeking behavior in life-threatening scenarios for children living with HIV in Uganda, Africa: a qualitative study
REFNo: HS7286ES

1. To explore experiences of caregivers and healthcare providers regarding PDM among children living with HIV after discharge from hospital. 2. To describe the role of social, cultural, economic and environmental context in health-seeking behavior after discharge for children living with HIV. 3. To explore perceived risk factors for post-discharge mortality among children living with HIV from the perspective of caregivers and health workers. 4. To describe strategies to prevent PDM among children living with HIV from the perspective of caregivers and health workers.
Uganda 2026-04-02 12:46:45 2029-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
An effectiveness-implementation trial of a peer mentorship intervention to help women navigate barriers to contraceptive use in rural Uganda
REFNo: HS7355ES

Main objective
: Our main aim is to increase women’s ability to overcome barriers to contraceptive use and to support adoption of self-injectable contraception. After promising findings in our pilot study, we propose to build on our strong, ongoing partnership between Makerere University in Uganda and the University of California, San Francisco to test “I-CAN” intervention on a larger scale.
Objectives
1. To test the effectiveness of a peer mentorship intervention on contraceptive use and contraceptive self-injection (Aim 1).
2. To examine the process of implementing I-CAN intervention; the ICAN’s reach to mentees, differential effectiveness, adoption and maintenance by mentors, implementation fidelity and innovations, and contextual factors (Aim 2)
3. To examine the cost-effectiveness of the peer mentorship intervention versus standard of care (counselling by health facility or community health workers) in supporting contraceptive use and contraceptive self-injection (Aim 3).

Uganda 2026-04-02 12:45:33 2029-04-02 Medical and Health Sciences Clinical Trial Non-degree Award
Godwin Godwin Tumuhairwe
ID: UNCST-2025-R021782
PRIVATE FINANCING, FINANCIAL MANAGEMENT SKILLS AND PERFORMANCE OF VOCATIONAL INSTITUTIONS IN BUSHENYI DISTRICT IN WESTERN UGANDA
REFNo: SS4955ES

i. To assess how source of financing affects the enrollment and performance of vocational institutions in Bushenyi District, Uganda
ii. To examine the relationship between private financing and resource utilization to vocational institutions training in Bushenyi District
iii. To examine the relationship between financial management skills and the performance of vocational institutions in Bushenyi District

Uganda 2026-04-02 12:35:27 2029-04-02 Social Science and Humanities Non-Clinical Trial Degree Award
Bendicto Kabiito
ID: UNCST-2019-R000846
‘Peace by Peaceful Means’: Repurposing ‘Akiriket’ for Peacebuilding in Pastoral Karamoja of Uganda
REFNo: SS5040ES

1. To investigate the nature of peace and pro-peace tendencies tenable through Akiriket. 2. To determine how Akiriket can be repurposed for effective and sustainable peacebuilding in a post-gun violence Karamoja, through a participatory approach. 3. To discern peace-building roles women and the youths can and should play in the customary governance-justice context of Akiriket.
Uganda 2026-04-02 12:31:22 2029-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniel Omollo Onyango
ID: UNCST-2026-R023329
Accelerating Women’s Collective Enterprises in Markets (AWCEM) in Uganda. Evaluation design to study the impact of Care’s AWCEM program in Uganda
REFNo: SS4935ES

CARE Uganda, with support from the Gates Foundation, is implementing market linkage supports to enhance sustainable market access for women collectives in Uganda. The study aims to understand how these strategies influence women’s participation and growth in enterprises and markets, and how they advance women’s economic achievement.
The primary objectives of the evaluation are to determine the program’s effects on women’s economic achievement, agency, social and political empowerment, and gender norms, as well as to evaluate the cost and return on investment (ROI) of the intervention. Secondary analyses will explore the added value of specific program components (e.g., product certification, marketing support) and the role of credit access.

Kenya 2026-04-01 14:30:42 2029-04-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Amy Suzanne Vatne Bintliff
ID: UNCST-2024-R016090
The impact of a curriculum to facilitate economic empowerment and wellbeing among Ugandan adolescents
REFNo: SS4743ES

To develop, implement, and assess an intervention to promote adolescent financial literacy and career readiness
USA 2026-03-30 13:03:10 2029-03-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Victoria Ndyanabangi
ID: UNCST-2021-R012645
IMPAACT 2024- Protocol Titled: Dose Finding, Safety and Tolerability Study of Daily Rifapentine Combined with Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age with and without HIV. DAIDS Study ID #38747,IND #171439
REFNo: HS6638ES

To determine weight-band dosing of a once-daily, 28-day regimen of isoniazid (INH) and rifapentine (RPT) (1HP) for the prevention of tuberculosis (TB) in children living with and without HIV.

Primary Objectives
Cohort 1 and Cohort 2
To determine the weight-band dosing of RPT taken as part of the 1HP regimen by evaluating:
⎯ PK RPT exposures among children with and without HIV
⎯ Safety and tolerability of the 1HP regimen among children with HIV while receiving twice-daily
DTG and children without HIV through 28 days of dosing

Cohort 2
• To evaluate the effect of RPT taken as part of the 1HP regimen on the PK of DTG
Secondary Objectives
Cohort 1 and Cohort 2
To evaluate the effect of covariates including age, weight, sex, ethnicity, nutritional status, and HIV-1 status on the PK of RPT taken as part of the 1HP regimen
• To evaluate the safety of the 1HP regimen through 24 weeks of follow-up
• To evaluate the palatability and acceptability of the 1HP regimen
• To evaluate adherence to the 1HP regimen

Cohort 2
• To evaluate the safety and tolerability of twice-daily DTG through 42 days among children with HIV who are receiving 1HP
• To evaluate virologic control (less than 200 copies/mL) at Day 42 among children taking a DTG-Based ARV treatment regimen co-administered with 1HP

Uganda 2026-03-30 12:54:54 2029-03-30 Medical and Health Sciences Clinical Trial Non-degree Award
MAURICE ALEX MUHWEZI MURARI
ID: UNCST-2026-R023968
Parenting Styles and Psychological Well-Being among Adolescents in Secondary Schools in Uganda: A Case of Kabale District in Western Uganda
REFNo: SS4926ES

1. To examine the relationship between parenting styles and adolescents’ psychological well-being in secondary schools in Kabale district.
2. To determine the most prevalent parenting styles among parents of adolescents in Kabale District.
3. To assess the relationship between parenting styles and adolescents’ self-esteem, and the mediating role of self-esteem in their psychological well-being.
4. To explore contextual and gender factors within Kabale District that influence the relationship between parenting styles, self-esteem, and psychological well-being of adolescents.

Uganda 2026-03-30 11:02:21 2029-03-30 Social Science and Humanities Non-Clinical Trial Degree Award
ELETH NYIRANKUSI
ID: UNCST-2025-R021587
PATIENTS’ WAITING TIME AND ASSOCIATED FACTORS AT UGANDA HEART INSTITUTE - A PHARMACIST’S PERSPECTIVE
REFNo: HS7234ES

General Objective
To examine patients’ waiting time and the associated factors influencing it from a pharmacist’s perspective at the Uganda Heart Institute.

Specific Objectives

1.To determine the average waiting time experienced by patients at the pharmacy unit of the Uganda Heart Institute.

2.To determine the institutional and operational factors contributing to prolonged pharmacy waiting times at the Uganda Heart Institute.

3.To explore pharmacists’ perspectives on the challenges and potential strategies for reducing patient waiting times.

Uganda 2026-03-30 10:59:36 2029-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PIUS NANYANGA
ID: UNCST-2026-R024505
THE EVOLUTION AND IMPACT OF DIGITAL HEALTH INTERVENTIONS ON CLINICAL WORKFLOWS, AND DECISION-MAKING AT UGANDA CANCER INSITUTE
REFNo: HS7331ES

1.Assess the impact of digital health interventions on the efficiency of
clinical workflows at the UCI.
2. Examine how digital tools influence patient-provider interactions and
contribute to streamlined clinical processes at the UCI.
3.Examine the impact of electronic medical records and clinical decision
support systems on diagnostic accuracy and treatment planning among healthcare
providers at the UCI.
4.
Explore how access to digital health intervention tools and real-time
patient data supports evidence-based clinical decision-making among healthcare
professionals at the UCI
Uganda 2026-03-27 18:07:27 2029-03-27 Medical and Health Sciences Non-Clinical Trial Degree Award
John Baguma
ID: UNCST-2025-R017835
Optimising protocols for domestic rearing of the palm weevil, Rhynchophorus phoenicis, in Uganda for value added food products and biofertilizer
REFNo: A684ES

To evaluate locally available organic waste materials as ingredients for optimizing rearing of R. phoenicis. 2. To assess the effect of artificial rearing on the nutritional value and organoleptic quality of R. phoenicis larvae. 3. To investigate the effects of incorporating palm weevil larvae into bread at different inclusion rates on microbial safety, nutritional qualities and sensory properties among palm weevil traditional consumers and non-consumers. 4. To investigate the use of R. phoenicis frass at different application rates as an organic biofertilizer in tomato production.
Uganda 2026-03-26 13:12:33 2029-03-26 Agricultural Sciences Non-Clinical Trial Degree Award
Agnes Namaganda
ID: UNCST-2021-R013797
Use of novel biomarkers for early detection and prediction of kidney disease in subclinical rheumatic heart disease
REFNo: HS7068ES

1. To determine the prevalence and factors associated with kidney dysfunction among children and youths previously diagnosed with subclinical RHD. 2. To determine the levels of kidney injury markers (Osteopontin, Cystatin C, NGAL) among children and youths previously diagnosed with subclinical RHD. 3. To assess the proportion of children and youths with elevated kidney injury markers that have CKD. 4. To develop and validate a prediction risk score for kidney dysfunction among children and youth previously diagnosed with subclinical RHD.
Uganda 2026-03-26 13:10:26 2029-03-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Sempebwa Brian
ID: UNCST-2025-R018098
Corporate Governance Practices and Financial Sustainability of SACCOS in Uganda acase of Greater Bushenyi
REFNo: SS4884ES

i. To examine the effect of board composition on financial sustainability of SACCOs
ii. To evaluate the effect of transparency on financial sustainability of SACCOs.
iii. To examine the effect of risk management on financial sustainability of SACCOs
iv. To assess the effect of regulatory compliance on the financial sustainability of SACCOs.
v. To evaluate the moderating effect of technology implementation on corporate governance practices and financial sustainability of SACCOs

Uganda 2026-03-26 13:08:27 2029-03-26 Social Science and Humanities Non-Clinical Trial Degree Award
Vesall Nourani
ID: UNCST-2022-R009221
Towards a Culture of Learning at Scale through Teacher Professional Development
REFNo: SS5074ES

To find out how the program addresses gender biases of teachers and foster inclusive learning environments, and what is its impact on girls’ educational outcomes?,To understand how this approach can be effectively integrated into existing teacher training institutions, and what factors enable its adaptation and scalability across diverse contexts?,To understand the downstream effect on student outcomes, including critical thinking, creativity, and the ability to address real-world challenges?,To understand the mechanisms through which collective learning in CoPs drives cultural transformation in schools?,To understand how action-research training impacts teacher beliefs, practices, and collaboration within and across schools?,To evaluate how teacher training affects student learning and how teachers develop knowledge and skills in their schools and how to properly scale good practices among new teachers.,
USA 2026-03-26 13:06:59 2029-03-26 Social Science and Humanities Non-degree Award
Christine Acio
ID: UNCST-2025-R017545
Risk Communication and Community Engagement in Arua City: Acase of Rabies
REFNo: SS5000ES

Specific Objectives 1. To explore community perspectives on knowledge, attitudes, and practices (KAP) regarding rabies prevention and control in Arua City. 2. To design a risk communication and community engagement (RCCE) model for rabies prevention and control in Arua City. 3. To test the effectiveness of the RCCE model as proof of concept in Arua City. 4. To assess acceptability of the RCCE model
Uganda 2026-03-26 12:53:46 2029-03-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
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