Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nalwanga Lillian Edith
ID: UNCST-2025-R022342
 HYPOXIC ISCHAEMIC ENCEPHALOPATHY CASEFATALITY, AND ITS ASSOCIATED FACTORS AMONG NEONATES AT KAYUNGA REGIONAL REFERRAL HOSPITAL
REFNo: HS7419ES

Main Objective 1. To determine the case fatality rate and its associated factors among neonates diagnosed with hypoxic-ischaemic encephalopathy at Kayunga Regional Referral Hospital. Specific Objectives 1. To determine the case fatality rate among neonates diagnosed with hypoxic-ischaemic encephalopathy at Kayunga Regional Referral Hospital between 1st January 2022 to 31st December 2025. 2. To identify maternal and intrapartum factors associated with hypoxic-ischaemic encephalopathy at Kayunga Regional Referral Hospital. 3. To identify neonatal factors associated with the hypoxic-ischaemic encephalopathy case fatality rate at Kayunga Regional Referral Hospital.
 Uganda 2026-04-27 11:40:12 2029-04-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Andrew Katumba
ID:
Machine Learning-based Algorithm for Automatic Screening of Pulmonary Tuberculosis using Chest X-rays in the Ugandan Population
REFNo: HS7323ES

1.Create an open, labelled, inclusive dataset for CXR images, clinical and lab information collected from the Ugandan population,
2.Develop machine learning models for automatic recognition of TB features in CXR images,
3.Integrate the developed models in a decision support web application,
4.Calibrate and validate the developed platform within Ugandan clinical settings.

 Uganda 2026-04-27 11:37:57 2029-04-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Okech
ID: UNCST-2024-R015996
 African Youth Panel: An investigation into the factors hindering youth from accessing dignified and fulfilling work in some communities in Uganda
REFNo: SS5046ES

Aim: To achieve a demonstrable impact on advancing access to employment and dignified and fulfilling work for young people, with a specific focus on young women, in the selected project countries.
Key Expected Outcomes (Objectives):
Objective Description
Social and Economic Opportunity An increase in social and economic opportunities for young people (the majority are young women).
Platform for Voice A vibrant participatory platform of youth voices shaping policy and practice.
Knowledge Generation Timely availability of relevant data and knowledge to inform policy and practice.
Advocacy Movement A movement of well-equipped young Africans advocating and seizing opportunities for dignified work.

 Uganda 2026-04-27 11:29:19 2029-04-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
GODWIN ATWINE
ID: UNCST-2025-R016926
 EXTENSION SERVICES AND AGRICULTURAL PRODUCTIVITY IN UGANDA: “A STUDY OF SEMBABULE AND KALUNGU DISTRICTS”
REFNo: SS4965ES

1.To understand the level of access to agricultural extension services in Sembabule and Kalungu districts. 2.To explore farmers' perceptions on the agriculture extension services in Sembabule and Kalungu districts. 3.To examine the outcome of agricultural extension services on agricultural productivity in Sembabule and Kalungu districts.
Uganda 2026-04-27 11:18:53 2029-04-27 Social Science and Humanities Non-Clinical Trial Degree Award
Suzan Nakasendwa
ID: UNCST-2025-R021931
 Harnessing AI-driven modeling for stroke types classification and prediction of survival outcomes in Uganda and Cameroon: A retrospective observational study
REFNo: HS7282ES

1. To comprehensively assess the structure, functionality, and maturity of the stroke data ecosystem within health facilities. 2. To examine the burden of stroke in Uganda using real-world evidence data from the national DHIS2 data system 3. To develop an optimal anomaly detection model for quality assurance of routine health facility stroke data. 4. To implement multi-model stroke subtype classifiers by integrating structured data using ensemble and deep learning models. 5. To deploy statistical and machine learning models in the prediction of time to hospital discharge among stroke patients with mortality as a competing risk.
 Uganda 2026-04-27 11:16:44 2029-04-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Siragi Kabale
ID: UNCST-2025-R020841
 PREVALENCE AND FACTORS ASSOCIATED WITH FEMALE SEXUAL DYSFUNCTION AMONG WOMEN WITH PELVIC FLOOR DISORDERS ATTENDING UROGYNECOLOGICAL CAMPS IN UGANDA
REFNo: HS7379ES

1. To determine the Prevalence of Female Sexual dysfunction among women with pelvic floor disorders attending urogynecology camps in Uganda
2. To determine the affected FSF domains among women with pelvic floor disorders attending urogynecology camps in Uganda
3. To determine the factors associated with Female Sexual dysfunction among women with pelvic floor disorders attending urogynecology camp in Uganda

Uganda 2026-04-27 11:14:29 2029-04-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Kabakyenga Asaph
ID: UNCST-2025-R019579
 UNIVERSITY SUPPORT SERVICES AND ACADEMIC PERFORMANCE OF STUDENTS
REFNo: SS4371ES

1. University support services have a positive significant influence on the academic self-efficacy of students in universities.
2. University support services have a positive significant influence on the academic achievement of students in universities.
3. University support services have a positive significant influence on students’ study time in universities.

 Uganda 2026-04-27 11:12:34 2029-04-27 Social Science and Humanities Non-Clinical Trial Degree Award
Sarah Nabukeera
ID: UNCST-2025-R021403
 Effectiveness of Postpartum Family Planning on Family Planning Uptake among Adolescent Girls and Young Women (AGYW) (10-24 years) in Rural Busoga Sub-region.
REFNo: HS7412ES

General Objective To evaluate the effectiveness of PPFP on FP uptake among AGYW (10-24 years) in the Busoga sub-region. This information will assist FP policymakers, programmers, and implementers in Uganda to thoroughly and critically examine the existing PPFP service delivery systems and processes and optimize investments for improved access and use of FP among AGYW. Specific Objectives The specific objectives will be under three sub-studies: Specific Objective I (Sub-study I) i. To synthesize the existing evidence on PPFP among AGYW (10-24 years) in Uganda. To determine the level of PPFP uptake among AGYW aged 10-24 years in Uganda between 2015 and 2025, by conducting a meta-analysis of the available evidence ii. To assess the existence of inequities in the level of PPFP uptake among AGYW 10-24 years in Uganda, using the available evidence. iii. To synthesize the existing evidence on the factors related to PPFP uptake among AGYW aged 10-24 years in Uganda Specific Objective II (Sub-study II) To explore the PPFP literacy needs, preferences, concerns and experiences of AGYW in the Busoga sub-region i. To explore the PPFP literacy needs of AGYW in the Busoga sub-region. ii. To find out preferences and concerns about PPFP literacy among AGYW in the Busoga sub-region. iii. To examine PPFP literacy experiences of AGYW in the Busoga sub-region. Specific Objective III (Sub-study III) To evaluate the effectiveness of the PPFP on FP uptake by AGYW (10-24 years) in the Busoga sub-region. i. To explore perspectives of policymakers, programmers, implementers and AGYW on fidelity, acceptability, adoption, penetration, relevance and equity of the PPFP among AGYW (10-24 years) in the Busoga sub-region. ii. To establish the effectiveness of the PPFP on FP uptake among AGYW (10-24 years) in the Busoga sub-region.
 Uganda 2026-04-27 11:02:36 2029-04-27 Medical and Health Sciences Non-Clinical Trial Degree Award
John Bosco Isunju
ID: UNCST-2019-R001803
 Gender Equality, Equity and Social Inclusion (GEEI) in Climate-Health financing in Uganda: pathways, barriers and opportunities.
REFNo: HS7363ES

To assess the perceptions and understanding of GEEI among stakeholders involved in climate-health projects, policies and programs.,To identify strategies for designing and implementing climate–health projects that deliberately reduce gender inequalities and prioritise the specific needs of women and vulnerable population groups.,To identify the opportunities, barriers and facilitators influencing access to, allocation of, and accountability for equitable climate–health financing in Uganda.,To examine how existing governance, policy, and institutional frameworks enable or constrain equitable financing for climate–health action in Uganda.,To assess the extent to which gender equality, equity and social inclusion considerations are integrated into climate–health policies, programmes, and interventions in Uganda.,To assess the integration and operationalisation of gender equality, equity and social inclusion within Uganda’s climate–health agenda and to identify ways in which climate and health financing can be structured to reduce gender disparities and prioritise the needs of women and other vulnerable population groups.,
 Uganda 2026-04-27 10:36:43 2029-04-27 Medical and Health Sciences Non-degree Award
Joanitah  Nalunjogi
ID: UNCST-2023-R008356
 Uptake of Clean Household Energy Use and its Impact on Respiratory and Cognitive Health Kawempe Division in Uganda
REFNo: HS7378ES

1. To determine the uptake of clean fuels among households in Kawempe division, Kampala City, Uganda. 2. To compare the respiratory health of people (all ages) living in biomass fuel-dependent households with that of clean fuel-dependent households. 3. To compare the cognitive function of people (all ages) living in biomass fuel-dependent households with that of clean fuel-dependent households
Uganda 2026-04-27 10:32:03 2029-04-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
 Feasibility of cervical cancer point-of-care testing
REFNo: HS7499ES

Primary Objective
1. To evaluate the feasibility of performing cervical cancer screening based on self-sampling.

Secondary objectives
1. To assess the feasibility of implementing information sessions to motivate cervical cancer screening with VIA.
2. To assess the feasibility of implementing information sessions to encourage self-sampling for HPV DNA testing.
3. To assess the feasibility outcomes as described by Gadke et al. of each of the three components (see Table 3).
4. To understand the potential role of Community Health Workers (CHWs) in the uptake of Cervical Cancer screening services based on the perspectives of healthcare providers, women, policy makers, and community stakeholders in Uganda.

Uganda 2026-04-24 15:18:34 2029-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Annet Sumba
ID: UNCST-2026-R023884
 A City as a Peace Project
REFNo: SS5095ES

1. To examine how cityness is lived and expressed by different actors in a post-conflict city context; 2.To investigate how informal and marginal actors contribute to the remaking of urban space and social relations; and 3. To analyse how public spaces and infrastructures function as affective and symbolic sites of peace-building.
 Uganda 2026-04-24 14:34:33 2029-04-24 Social Science and Humanities Non-Clinical Trial Degree Award
Allen Kabagenyi
ID: UNCST-2019-R000665
 A Gendered Analysis of Preparedness and Response to Natural Disasters in Kasese District
REFNo: SS4854ES

To examine household-level flood and landslide response strategies in Kasese District, with a focus on the extent of response mechanisms, the socio-economic and cultural factors influencing their effectiveness, and gender-based differences in disaster response approaches.
Uganda 2026-04-24 14:28:53 2029-04-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 A5424 Menopausal Hormone Therapy for Women Living with HIV (HoT)
REFNo: HS7391ES


1.2 Primary Objective

1.2.1 Determine the effects of HT on VMS in WLWH in the late menopausal transition or early postmenopause.

1.3 Secondary Objectives

1.3.1 Evaluate the safety and tolerability of HT as compared to placebo.

1.3.2 Determine the effect of HT on neurocognition.

1.3.3 Determine the effect of HT on mood.

1.3.4 Determine the effect of HT on sleep.

1.3.5 Determine the effect of HT on quality of life.

1.3.6 Determine the effect of HT on sexual function.

1.3.7 Determine the effect of HT on weight, waist circumference, and waist-to-hip ratio.

1.4 Exploratory Objectives

1.4.1 Determine the effect of HT on markers of bone turnover.

1.4.2 Determine the effect of HT on markers of cardiometabolic health.

1.4.3 Determine the effect of HT on systemic markers of inflammation and immune activation.

1.4.4 Determine the effect of HT on HIV reservoir size, clonality, and activity.

1.4.5 Determine the effect of HT on measures of physical function.

1.4.6 Determine the effect of HT on the rectal and vaginal microbiome.

1.4.7 Explore the effect of HT on all primary and secondary outcomes by antiretroviral regimen.

1.4.8 Explore exposure-response relationships between estradiol pharmacokinetics (PK) and study outcomes in those treated with estradiol.

1.4.9 Evaluate acceptability and feasibility of ambulatory monitors for VMS and sleep on a subset of participants.

1.4.10 Explore agreement between subjective VMS frequency with objective VMS frequency in a subset of participants.


 Uganda 2026-04-24 13:20:15 2029-04-24 Medical and Health Sciences Clinical Trial Non-degree Award
Peter Olupot Simon
ID: UNCST-2025-R022744
 Implementation of Sustainable Public Procurement in the Procurement of Works in Uganda’s Central Government Entities
REFNo: SS5085ES

i. To examine the relationship between external pressures and implementation of SPP.
ii. To examine the relationship between resource heterogeneity and implementation of SPP.
iii. To examine the relationship between stakeholder engagement and implementation of SPP.
iv. To examine the mediating role of resource heterogeneity in the relationship between external pressures and implementation of SPP.
v. To examine the mediating role of resource heterogeneity in the relationship between stakeholder engagement and implementation of SPP.
vi. To examine the moderating effect of procurement officers’ attitude in the relationship between resource heterogeneity and implementation of SPP.
vii. To examine how procurement officers’ attitude will moderate the relationship between external pressures and implementation of SPP through resource heterogeneity.
viii. To examine how procurement officers’ attitude moderates the relationship between stakeholder engagement and implementation of SPP through resource heterogeneity.

 Uganda 2026-04-20 9:42:42 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Mboizi Baldwin
ID: UNCST-2020-R014356
 Optimising Eligibility Criteria for Participant Selection in Maternal Vaccine Trials in Low-Resource Settings (ACCESS).
REFNo: HS7404ES

1. To conduct a systematic review and analyse existing eligibility criteria used in maternal vaccine trials globally, with a focus on their applicability and limitations in low-resource settings.

2. Determine the proportion of women ineligible to participate in maternal vaccine clinical trials at Kawempe National Referral Hospital using an eligibility assessment tool.

3. Determine the pregnancy outcomes in women ineligible for maternal vaccine trials at Kawempe National Referral Hospital using an eligibility assessment tool.

4. Identify factors associated with pregnancy outcomes among pregnant women excluded from trial participation.

Uganda 2026-04-20 16:50:32 2029-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Yudaya Nakyeyune
ID: UNCST-2026-R024597
 Using Play in Culturally Responsive Ways to Enhance Children’s Numeracy Skills Achievement in Refugee-Hosting ECD Centers in Kampala
REFNo: SS5116ES

1. To analyze children's voices of learning through play in refugee hosting ECD centers in Kampala.
2. To identify the challenges teachers encounter when using play in the teaching of numeracy in refugee hosting ECD centers in Kampala
3 To establish the impact of engagement in Continuing Professional Development (CPD) on teachers' knowledge regarding the use of play-based methods in culturally responsive ways in refugee hosting ECD centers in Kampala
4. To assess the impact of engagement in culturally responsive learning through play activities on children's numeracy achievement in refugee hosting ECD venters in Kampala
Uganda 2026-04-20 16:47:28 2029-04-20 Social Science and Humanities Clinical Trial Degree Award
PIUS OKELLO ROBERT
ID: UNCST-2026-R024675
 School Management Functions and Academic Performance of Students in Government-Aided Secondary Schools A Case of Dokolo District, Uganda
REFNo: SS5162ES

Purpose of Study
To investigate the contribution of School Management Functions and its relationship with academic Performance of Students in Government-aided Secondary Schools in Dokolo District.


Specific Objectives
1. To evaluate the effect of management planning function on academic performance of students in Government-aided Secondary Schools in Dokolo District.

2. To analyze the effect of management organizing function on academic
performance students in Government-aided Secondary Schools in Dokolo District.

3. To assess the role of management controlling function on academic performance of students in Government-aided Secondary Schools in Dokolo District.

4. To investigate the mediating effects of perceived on relationship between school management functions and academic performance of students in government-aided Secondary Schools in Dokolo District.
 Uganda 2026-04-20 16:25:31 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
Clifton IRAHUKA
ID: UNCST-2025-R018482
 Evaluating the Feasibility and Acceptability of an Offline-First AI Health Companion for Frontline Health Workers in Uganda: A Mixed-Methods Concurrent Triangulation Study
REFNo: HS7408ES

General objective To evaluate the feasibility and acceptability of an offline-first AI Health Companion for clinical decision-making among Frontline Health Workers in health facilities in Luweero District, Uganda. Specific objectives To assess the feasibility of the offline-first AI Health Companion application among FHWs in public health facilities in Luweero district. To evaluate the acceptability of the offline-first AI Health Companion among FHW in public health facilities in Luweero district. To determine the individual, technological and organisational factors that influence the adoption and sustained use of AI clinical decision support tools among FHWs in public health facilities in Luweero district. To explore the facilitators of and barriers to scaling offline AI decision support tools among FHWs in Luweero district
Uganda 2026-04-20 16:19:00 2029-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Madrine Nabukenya Mkisa
ID: UNCST-2026-R024084
 Psychological Resilience among Teachers in Private Secondary Schools in Wakiso District, Uganda.
REFNo: SS5118ES

i) To document factors that influence the psychological resilience of teachers in private secondary schools in Wakiso district ii) To explore the perception of teachers on self-efficacy, affective flexibility, and spiritual well-being in private secondary schools in Wakiso district. iii) To assess the influence of self-efficacy, flexibility, and spiritual well-being on teachers’ ability to adapt to employment terms (remuneration, job security, career growth, workload management, resource management) in a private secondary school in Wakiso district. iv) Examine the relationships that may exist between self-efficacy, flexibility, spiritual well-being, and psychological resilience among teachers in private secondary schools in Wakiso district.
Uganda 2026-04-20 16:16:00 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
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