Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ARINAITWE ENID
ID: UNCST-2024-R002911
 SPILLOVER, BOUNDARY MANAGEMENT, SOCIAL NORMS AND EMPLOYEES’ WORK-LIFE BALANCE IN NATIONAL REFERRAL HOSPITALS IN KAMPALA – UGANDA
REFNo: SS3333ES

To analyse the combined effect of positive spillover, boundary management and social norms on employees’ work-life balance in national referral hospitals in Kampala.,To explore the effect of social norms on the work-life balance of employees in national referral hospitals in Kampala.,To evaluate the influence of boundary management practices on the work-life balance of employees in national referral hospitals in Kampala.,To assess the impact of spillover on the work-life balance of employees in national referral hospitals in Kampala.,The primary goal of this study is to investigate how spillover, boundary management, and social norms impact the work-life balance of employees at national referral hospitals in Kampala.,
 Uganda 2024-10-31 17:33:43 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Mary Bekoreire Baremirwe
ID: UNCST-2024-R003317
 Civil Society Organizations and Anti-Corruption Efforts in Uganda: Examining their Impact and Challenges
REFNo: SS3307ES

To examine the impact of CSOs in the fight against corruption in Uganda and their limitations in the pursuit of their goals,3. To recommend practical strategies can be adopted to enhance a conducive environment for CSOs operation in the fight against corruption in Uganda.,2. To examine the structural and process barriers that have affected the effectiveness of CSOs in the fight against corruption in Uganda.,
 Uganda 2024-10-31 17:32:27 2027-10-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
RICHARD ANGUALIA LAUS
ID: UNCST-2024-R002829
 Organisational Politics and quality of road infrastructure Services in Kampala Capital City Authority in Uganda
REFNo: SS3375ES

3. Examine the influence of ethical management practices on sustainability of road infrastructure services in KCCA,2. Assess the contribution of institutional structures to resilience of roads infrastructure services delivery in KCCA,1. Analyze the influence of power dynamics on safety of road infrastructure service delivery in KCCA.,The main objective of the study is to examine the contribution of organizational politics to quality of roads infrastructure services deliverer in Kampala Capital City Authority (KCCA),
 Uganda 2024-10-31 17:29:41 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
John Bosco Ddamulira Mayanja
ID: UNCST-2022-R010819
 Evaluation of the Integrated Community-Based HIV Service Delivery Model (ICSDM) in Uganda: Analysis of Outcomes, experiences, and Cost.
REFNo: HS4916ES

The overall objective of the evaluation is to assess the implementation of ICSDM in Uganda to generate evidence on how well the model is working, and whether the desired health outcomes are being achieved.
1) To assess to what extent the implementation process for the delivery of ICSDM services is in accordance with the implementation guidelines and plan.
2) To assess the outputs as well as the primary (viral load re-suppression) and secondary outcomes of the implementation of ICSDM.
3) To explore the experiences, facilitators, challenges and lessons learned implementing ICSDM—the implementer and beneficiary perspective.
4) To determine annual and unit costs of the ICSDM program

 Uganda 2024-10-31 17:27:42 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olivia Nakisita
ID: UNCST-2020-R014431
 A community Intervention to Improve the Sexual and Reproductive Health of Adolescents and Young People in Wakiso District, Uganda
REFNo: HS4875ES

To asses the impact of the multi strategy intervention to improve the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,To implement a multi component intervention to improve the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,To assess the baseline situation of the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,To improve the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,
 Uganda 2024-10-31 17:24:11 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 Secondary distribution of HIV self-testing by Female Sex Workers, pre-exposure prophylaxis (PrEP) starter packs and brief counseling to promote PrEP initiation and persistence among high-risk men in Uganda
REFNo: HS4891ES

Determine acceptability, feasibility, and safety of the intervention, and preliminary estimates of the potential for the intervention, compared to the control, to promote PrEP initiation, adherence, and persistence among male clients,Conduct an initial (stage 1a) small pilot of the intervention and refine it in preparation for the stage 1b pilot trial,Create the proposed Kayungirizi intervention to promote PrEP initiation and persistence among male clients of FSW through qualitative research informing adaptation and integration of components of local models and aspects of evidence-based interventions,Our overall hypothesis is that secondary distribution of HIVST by FSW to their male clients as an entry point to generate demand for PrEP, followed by an FSW-led intervention to address ongoing structural, interpersonal, and individual-level barriers (convenience, confidentiality/stigma, flexibility) will promote PrEP initiation, adherence, and persistence among male clients. ,
 Uganda 2024-10-31 17:21:44 2027-10-31 Medical and Health Sciences Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 AIR QUALITY AND FOOD PREPARATION IN LOW -INCOME COMMUNITY IN KAMPALA-UGANDA: ACOMPARATIVE STUDY OF TWO COOKING STOVES
REFNo: HS5085ES

The overall purpose of the study is to determine if the novel samuchit steam cookers use a different amount of fuel, generate lower levels of PM, and have reduced cooking times compared to the traditional sigiri charcoal stoves,
 Uganda 2024-10-31 17:14:55 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAOME KAKUNDWA
ID: UNCST-2023-R007057
 Corporate governance practices and financial performance of Saving and Credit Cooperatives (SACCOs) in Bushenyi Uganda
REFNo: SS3030ES

To examine the influence of member participation on the financial performance of SACCOs in Western Uganda,To establish the effect of Transparency & accountability on the financial performance of SACCOs in Western Uganda,To examine the influence of Audit committee practices on the financial performance of SACCOs in Western Uganda,To assess the effect of Board practices on the financial performance of SACCOs in Western Uganda,
 Uganda 2024-10-31 16:50:17 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Brown Alice
ID: UNCST-2023-R006208
 A Longitudinal Study of the Development of Multimodal Combinational Communication in Chimpanzees
REFNo: NS834ES

To understand and explore the ontogeny of combinational communication in chimpanzees (Pan Troglodytes) to provide insights to the evolution of human language. To understand how non-adult chimpanzees develop the multimodal combinatorial communication that has been seen in adult chimpanzees. To assess the role social learning may play in the acquisition of multimodal combinatorial communication, by (i) comparing non-adult repertoires to those of their mother (social learning model) and father (not a social learning model) and (ii) by examining cross -community differences in adult repertoires.
UK 2024-10-31 16:48:44 2027-10-31 Natural Sciences Non-Clinical Trial Degree Award
ROVINE NALUYIMBAZI
ID: UNCST-2024-R005302
 Expanding laparoscopic simulation in Uganda
REFNo: HS4783ES

Aim 3: Create, conduct, and review a hybrid laparoscopic surgery training course for practicing Ugandan surgeons.,Aim 2: Create a low-cost, high-fidelity laparoscopy training model. We will utilize the Duke-Muk educational partnership that forms the foundation for the Shipping Container MakerSpaces to develop and build a laparoscopic training model, demonstrating the effectiveness of the previously developed infrastructure for biomedical engineering.,Aim 1: Assess level of baseline laparoscopic training and experience for Ugandan surgeons. We will survey the members of the Ugandan Surgical Society regarding their needs, expectations, and willingness to participate in a laparoscopic training course,We will assess the needs of local surgeons and trainees about their needs and experiences in laparoscopy to develop a low-cost box-trainer that is manufactured locally. This box will enable LMIC surgeons to develop the fundamental skills necessary to perform laparoscopy and improve surgical patient outcomes. The developed box trainer will form the foundation of a hybrid laparoscopy training course to be facilitated by local surgical and medical educators.,
 Uganda 2024-10-31 16:41:56 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
 LIVED EXPERIENCES OF SURVIVORS OF VACCINE PREVENTABLE DISEASES IN UGANDA
REFNo: HS4189ES

3. To analyze the views of the caregivers to and survivors of vaccine preventable diseases in Uganda concerning the role of vaccines and vaccination in disease prevention?,2. To determine and document the lived experiences of caregivers to people suffered from or died from vaccine preventable diseases in Uganda?,1. To determine and document the lived experiences of survivors of vaccine preventable diseases in Uganda?,
 Kenya 2024-10-31 16:35:06 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Validation of the liquid biopsy to diagnose endemic Burkitt lymphoma in children in Uganda.
REFNo: HS4525ES

To compare the performance of the liquid biopsy test with conventional pathology in diagnosing endemic Burkitt lymphoma in Uganda. ,To evaluate the turnaround times for liquid biopsy and conventional pathology for diagnosing EBVL in real life settings in Uganda,To compare the sensitivity and specificity of liquid biopsies versus locally enhanced available pathology in Uganda.,To validate the liquid biopsy to diagnose endemic Burkitt lymphoma in children and young adults in Uganda.,
 Uganda 2024-10-31 16:17:43 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PIUS MATOVU DDUMBA
ID: UNCST-2024-R004025
 Family Environment and Depressive Symptom among older adults in Central Uganda: The Mediating Role of Patient Factors
REFNo: SS2854ES

6. To test the causal model indicating whether patient factors have a mediating effect on family environment and depressive symptoms among older adults in Central Uganda using SEM modeling.,5. To assess the influence of patient factors on depressive symptoms among older adults in Central Uganda.,4. To examine the relationship between patient factors and family environment among older adults in Central Uganda.,3. To examine the influence of system maintenance on depressive symptoms among older adults in Central Uganda.,2. To assess the effect of personal growth on depressive symptoms among older adults in Central Uganda.,1. To analyze the influence of interpersonal relations on depressive symptoms among older adults in Central Uganda.,The purpose of this study is to analyze the effect of family environment on depressive symptoms among older adults in Central Uganda.,
 Uganda 2024-10-31 16:12:27 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
ANDREA KADDU KAGGWA
ID: UNCST-2024-R004958
 FREQUENCY, COURSE, OUTCOMES AND FACTORS ASSOCIATED WITH DELIRIUM AMONG ADULT PATIENTS ADMITTED TO THE UGANDA CANCER INSTITUTE RefNo: Mak-SOMREC-2024-900
REFNo: HS4862ES

1. To determine the frequency of delirium among adult patients admitted to the UCI. a). to determine the prevalence of delirium among adult patients on admission to the UCI. b). to determine the incidence of delirium among adult patients admitted to the UCI during a 1-week period of follow up 2. To determine the course and outcome of delirium during a 1-week period after diagnosis among adult patients admitted to the UCI. 3. To determine the factors associated with delirium among adult patients admitted to the UCI.
Uganda 2024-10-31 16:10:08 2027-10-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Annet Nanvubya
ID: UNCST-2025-R015525
 Tuberculosis case finding at the completion of the Ubuntu clinical trial: a substudy to CoVPN 3008 (Ubuntu).
REFNo: HS4715ES

Primary Objective 1: Identify participants with previously undiagnosed tuberculosis (TB) disease, including subclinical TB.
Primary Objective 2: Identify demographic and other participant characteristics that are associated with the diagnosis of TB, including subclinical TB.
Primary Objective 3: Investigate peripheral blood biomarkers associated with diagnosis of TB, including subclinical TB.
Primary Objective 4: Follow participants with confirmed TB for six months and identify those that remain microbiologically positive for TB.

 Uganda 2024-10-31 16:05:35 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Verdolin
ID:
Establishing a Long-Term Behavioral and Ecological Monitoring Research Program in Queen Elizabeth Conservation Area
REFNo: NS841ES

This research aims to explore several critical issues affecting savannah ecosystems:
1. Impact of Macro and Microplastics on Wildlife: Plastic pollution is an emerging threat to wildlife health in savannah ecosystems. Both macroplastics and microplastics can cause physical harm, ingestion issues, and toxicological effects in wildlife, disrupting health, reproduction, and survival rates.
2. Sources of Plastic Pollution: Identifying and understanding the critical sources of plastic pollution within and between communities is essential. This includes examining local waste management practices, the role of tourism, and community awareness and behaviors regarding plastic use and disposal.
3. Animal Movement Patterns and Ecological Impact: Changes in animal movement patterns, driven by factors such as habitat fragmentation, climate change, and human disturbances, can significantly affect feeding ecology and population dynamics of predators, prey, and other fauna. Understanding these changes is vital for predicting ecological outcomes and managing wildlife populations.
4. Bush Encroachment Patterns and Drivers: Bush encroachment, the process where woody plants invade grassland areas, alters the structure and function of savannah ecosystems. This study will characterize the patterns of bush encroachment and investigate the factors driving these changes in different zones of the park, such as fire regimes, grazing pressure, and climatic variables.
5. Disease Outbreaks and Pathogen Evolution: Disease outbreaks, including anthrax, pose a significant threat to wildlife populations. This research will focus on understanding the patterns of these outbreaks, how pathogens are evolving, and predicting future impacts on wildlife health and ecosystem stability.
 USA 2024-10-31 15:52:31 2027-10-31 Natural Sciences Non-Clinical Trial Non-degree Award
Valence Mfitumukiza
ID: UNCST-2024-R004532
 Enteric pathogens and intestinal injury in Ugandan children with malaria RefNO: KABREC-2024-155
REFNo: HS4732ES

To examine the association of invasive enteric pathogens with stool and circulating host markers of intestinal and systemic inflammation,To define the frequency of common enteric pathogens among children with malaria and diarrhea, comparing to controls without malaria and/or diarrhea.,To characterize enteric pathogens in children with falciparum malaria and diarrhea as potential drivers of intestinal leak and systemic inflammation,
 Uganda 2024-10-31 15:49:23 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Antje  Daniel
ID: UNCST-2024-R003872
 "New kids on the block”? Youth environmental engagement and Fridays for Future. An intersectional and global perspective
REFNo: SS3040ES

This new environmental youth engagement as a young and quickly developing movement has not received in-depth academic attention, neither in the field of youth studies nor in social movement studies, especially not youth engagement in the Global South (see below). The motives of youth and their particular understandings of engagement remain insufficiently investigated. In addition, there is increasing criticism of youth environmental activism, namely that FFF is at least in Europe ‘white’ and supported by a well-educated middle-class elite leading to the accusation that it reproduces hierarchies (see below). However, there are hardly any academic studies that examine privileges, hierarchies and discrimination within FFF from an intersectional perspective. In order to respond to these research gaps an intersectional perspective is used to understand the motives and activism of youth in Austria, Bangladesh and Uganda and thereby their global interrelatedness. This scientifically necessary and timely research is also politically relevant since youth are acting at the forefront of environmental movements. In addition, youth engagement participants have become increasingly integrated into the international politics of the UN and are in dialogue with politicians. It can be argued further that youth engagement is not ‘just’ a certain stage of life but that it lays the foundation for transformation processes (Harré 2016; Riemer et al. 2016). Young advocates are frequently those taking up important political and social leadership in the future due to their interest and experience of advocacy (Giugni 1998; Leistner 2018): They are a “cohort of citizens who will be active participants in democracy” (Fischer 2019, 430).
Because a new youth activism emerged which is unique due to its global scope and the low average age new scientific perspectives are needed to analyse this phenomenon: A synthesis of youth and civil society studies combined with intersectionality and a comparative case study design offer an original analytical framework. This framework will provide in-depth knowledge on context-specific differences of youth engagement in Austria, Bangladesh and Uganda and commonalities of global youth activism and its activism towards ecological transformation. This research is needed scientifically because FFF is one of the major civil society players in global environmental politics and in manifold national contexts.


Germany 2024-10-31 15:48:00 2027-10-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
 Molecular evolution of Mycobacterium avium subspecies paratuberculosis (MAP) in Africa (Phase II)
REFNo: NS860ES

i) To determine the occurrence of Mycobacterium avium subspecies paratuberculosis in water and animal products
ii) To determine the persistence of MAP in the farm environment in Uganda
iii) To determine gut microbiome profile of animals infected with MAP
v) To identify virulence factors of African MAP strains
vi) To investigate the biology of susceptibility and resistance of cattle to MAP
 Uganda 2024-10-30 12:12:45 2027-10-30 Natural Sciences Non-Clinical Trial Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
 Substance and Alcohol Use, Dating Violence, and Sexually Transmitted Infections among Makerere University Students in Kampala Uganda
REFNo: SS3276ES

1.3 Study Aims
Therefore, this study aims to investigate the prevalence and correlates of alcohol use, drug use, dating violence (DV), depression, and sexually transmitted infections risk among University Students in Uganda.
Specific aims of the study include:
Aim 1: To determine the prevalence and correlates of alcohol use, drug use, and dating violence among students at Makerere University, Kampala, Uganda.
Hypothesis 1: Alcohol and DV risk profiles will be significantly different among male and female students and socio-demographics (age and sex, socio-economic status, and environmental factors).
Aim 2: To estimate the association between dating violence and sexually transmitted infections risk among students at Makerere University, Kampala, Uganda.
Hypothesis 2: The prevalence of HIV risk and sexually transmitted infections will be greater among science students compared to those from the arts and humanities.
Analysis: We will determine the risk factors for dating violence, Intimate Partner Violence, HIV risk, STIs
Aim 3: To determine the association between dating violence and depression among students at Makerere University.

Uganda 2024-10-23 18:02:34 2027-10-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
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