Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Identifying Barriers to Infection Prevention & Control Guideline Adherence in Western Uganda.
REFNo: HS5360ES

Primary Objectives The primary objective of the proposed project is to demonstrate the effects of limited physical facility infrastructure, diminished supplies, and gaps in IPC knowledge amongst HCP and how they may relate to IPC practice implementation at the health facility level to inform efficient and effective future improvement efforts. Specific Aims AIM 1: Evaluate adherence to national IPC guidelines across a variety of healthcare facility levels in Western Uganda via a standardized observation protocol through facility-level evaluations. 1A. Guided by Uganda’s national IPC best practices for healthcare facilities and a standardized facility-level checklist adopted from the World Health Organization, we will perform observations of the facility’s physical characteristics, healthcare supplies, and healthcare personnel workflow, including observations of hand hygiene adherence with a standardized checklist. AIM 2: Assess IPC knowledge, attitudes, and practices of healthcare personnel at multiple levels of Uganda’s national healthcare system, identifying primary barriers to National IPC Guideline adherence. 2A. Healthcare Personnel Surveys: Surveys will consist of both qualitative and quantitative elements to ascertain information on their awareness of foundational IPC concepts within national guidelines, circumscribe a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes that may prevent rigorous adherence to IPC guidelines. 2B. Healthcare Personnel Focus Group Discussions: Focus group discussions will be oriented in such a manner as to ascertain common themes and information on awareness of foundational IPC concepts, gain a perspective on the experience of IPC practices across a variety of facility levels and HCP roles, and understand what limitations are experienced by HCP during their daily patient care-oriented activities. Through these discussions, we hope to gain a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes, gaps in IPC education and/or training, and HCP workflow concerns that may prevent rigorous adherence to IPC guidelines.
Uganda 2024-12-23 11:57:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 Stakeholder perspectives for the approach to treatment recommendations for kids presenting with advanced or incurable cancer
REFNo: HS5203ES

Using the instrument described in 1.1, identify personal, professional, and contextual factors influencing the perspectives and decision-making approaches of key non-physician stakeholders in Uganda in the upfront care of children diagnosed with advanced or incurable cancer through qualitative data collection and analysis.,To adapt an existing instrument for use in Uganda that helps explore the personal, professional, and contextual factors that influence the perspectives and decision-making approaches of key non-physician stakeholders (patients, families, multidisciplinary clinicians), specifically with respect to recommending upfront curative treatment versus non curative treatment (for example, with palliative-intent) in children diagnosed with advanced or incurable cancer in LMICs.,
 Uganda 2024-12-23 11:55:35 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Duula Waiswa
ID: UNCST-2024-R015879
 BURDEN AND SPATIAL DYNAMICS OF TICK SPECIES AMONG CATTLE GRAZING ALONG THE BUFFER ZONE OF LAKE NAKUWA IN KALIRO DISTRICT
REFNo: A529ES

1. Determine the burden of tick species infesting cattle grazing along the buffer zone of Lake Nakuwa.
2. Determine spatial dynamics of the different tick species infesting cattle grazing along the buffer zone of Lake Nakuwa
3. Identify factors promoting and maintaining high tick infestation burdens along the buffer zone of Lake Nakuwa.

Uganda 2024-12-23 11:54:12 2027-12-23 Agricultural Sciences Non-Clinical Trial Degree Award
Edith Namakula
ID: UNCST-2022-R006923
 Pethidine versus Morphine use for management of postoperative pain in Mulago National Referral Hospital, Uganda
REFNo: HS5240ES

1. To determine the prevalence of pethidine versus morphine prescription for the management of postoperative pain in MNRH, Uganda.
2. To explore the side effects experienced during the use of pethidine versus morphine for the management of postoperative pain in MNRH, Uganda.
3. To determine the factors associated with pethidine prescription for the management of postoperative pain in MNRH, Uganda.
4. To explore barriers and facilitators of pethidine versus morphine prescription in the management of postoperative pain in MNRH, Uganda.

 Uganda 2024-12-23 11:53:21 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Birungi
ID: UNCST-2024-R015642
 Receiving cash amidst competing norms: the case of breastfeeding South Sudanese refugees in bidi-bidi settlement, uganda.
REFNo: SS3525ES

To explore how breastfeeding South Sudanese refugees navigate their cultural norms and cope with cash transfer project norms.

Specific objectives.
1. To establish the cultural norms that guide breastfeeding among South Sudanese refugees in bidi-bidi settlement.
2. To examine how beneficiaries relate with the official norms (project and state norms) in bidi-bidi settlement.
3.To assess the impact of cultural norms on the participation of south sudenese refugees in cash transfer interventions in bidi-bidi settlement.
Uganda 2024-12-23 11:52:27 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
JAMMY OMARA
ID: UNCST-2022-R009800
 ASSESSING DIFFERENTIAL DIAGNOSES, ASSOCIATED FACTORS AND GEOSPATIAL DISTRIBUTION OF CHRONIC LOWER LIMB ULCERS AMONG ADULTS IN ZOMBO DISTRICT, UGANDA
REFNo: HS5272ES

General objective
To determine differential diagnoses and associated factors for chronic lower limb ulcers among adults in Zombo district.

specific objectives
1. To determine the differential diagnoses for chronic lower limb ulcers among adults in Zombo district
2. To describe the associated factors with chronic lower limb ulcers among adults in Zombo district
3. To describe the geospatial distribution of individuals with chronic lower limb ulcers in Zombo district
 Uganda 2024-12-23 11:51:16 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Filippo Ferraro
ID: UNCST-2024-R016002
 Key Performance Indicator Framework for refugees integration in Uganda
REFNo: SS3441ES

The main objectives of the study are to:
1. ldentify the specifics support needs of refugees in Uganda.
2. Explore the perception and understanding of refugee’s local people and stakeholders
on the concept of integration.
3. Explore the existing welfare and integration programme available in Uganda.
4. Determine the facilitators and the barriers to the integration of refugees in Uganda.
5. Develop a Key Performance Indicator framework for the integration of refugees in
Uganda.

 Italy 2024-12-23 11:50:16 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Chinatsu  Hattori
ID: UNCST-2024-R002354
 Determinants of Family Planning use among women of reproductive age in refugees and host communities in Lamwo District, Uganda: a cross-sectional study
REFNo: HS5291ES

Main Objective To identify the factors influencing the utilization of family planning methods among women of reproductive age in the refugee settlement and host communities in Lamwo District, Uganda. Specific Objectives (i)To estimate the contraceptive prevalence among women of reproductive age in both refugee settlements and host communities. (ii)To analyze contraceptive use in terms of readiness, willingness, abilities, and other associated factors among women of reproductive age in refugee settlements and host communities.
 Japan 2024-12-23 11:49:09 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
 OUTCOMES AND HEALTHCARE NEEDS OF PATIENTS WITH HIV AND KIDNEY DISEASE IN UGANDA.
REFNo: HS5305ES

1. To determine the contribution of CKD to 5-year mortality among PWH in Uganda.
2. To determine barriers and facilitators to nephrology care among PWH and CKD comorbidity in Uganda.

 Uganda 2024-12-23 11:46:08 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAKAYISO  ESEZA
ID: UNCST-2024-R002957
 INFLUENCE OF SAVINGS AND CREDIT COOPERATIVE STRATEGIES ON FINANCIAL EMPOWERMENT OF WOMEN IN MASAKA DISTRICT, UGANDA.
REFNo: SS3454ES

The study aims to: i. Evaluate the impact of financial training and advisory services on women\'s financial literacy and decision-making in Masaka District. ii. Investigate the effectiveness of loan and credit strategies in promoting women\'s financial empowerment. iii. Assess the role of savings strategies in fostering women\'s financial empowerment. iv. Evaluate the influence of government policies on women\'s access to financial services and economic opportunities. v. Examine how cultural factors moderate the relationship between SACCO strategies and women\'s financial empowerment.
 Uganda 2024-12-23 11:44:21 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Stephen Tukwasibwe
ID: UNCST-2022-R011535
 Surveillance of malaria drug and diagnostic resistance in newly arrived refugees in Uganda
REFNo: HS5317ES

1. To characterize drug resistance profiles of P. falciparum parasites collected from newly arrived refugees in Uganda
2. To evaluate the prevalence of P. falciparum HRP-2 gene deletions that mediate diagnostic resistance in newly arrived refugees in Uganda

 Uganda 2024-12-23 11:42:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 An Evaluation of Perceptions and Effectiveness of the Ethical Review Process at Makerere University: A pilot Evaluation at the School of Health Sciences Research and Ethics Committee
REFNo: HS5322ES

1. Assess the perceptions of researchers (from the departments of pharmacy, nursing, dentistry, staff at Makerere University and researchers outside the institution) regarding MaKSHSREC’s ethical review process.
2. To assess the level of satisfaction among researchers on the existing MaKSHSREC ethical review processes.
3. Assess the efficiency and effectiveness of MaKSHSREC ethical review processes.
4. Explore the challenges and areas for improvement in the current MaKSHSREC ethical review processes.

Uganda 2024-12-23 11:38:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PAULA KWOREKWA
ID: UNCST-2024-R005035
 Assessing the Impact of COVID-19 on the Knowledge, Attitude, and Practice of Medical Waste Management among Waste Handlers at Luweero General Hospital
REFNo: HS5350ES

Main Objective:
To investigate the impact of COVID-19 on the Knowledge, attitude, and practice of medical waste management among waste handlers at Luweero General Hospital.
Specific Objectives:
1. To determine the knowledge of medical waste handlers in recommended waste management practices following the COVID-19 pandemic.
2. To investigate the attitude of medical waste handlers towards practicing the recommendations for proper Medical Waste Management in the post COVID-19 pandemic era.
3. To compare the practices for medical waste management before and after the COVID-19 pandemic.


Uganda 2024-12-23 11:37:27 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Aziku
ID: UNCST-2023-R007595
 Baseline Study for Safe and Inclusive Cities Project -Uganda.
REFNo: SS3476ES

To evaluate the achievement of the programme’s intended outcomes, integrating qualitative insights and quantitative data on change in outcome indicators over time (from endline to end-line).

Identify and validate good practices, learnings, and examples of innovation on gender transformative programming.

To generate practical recommendations related to the programme outcomes and the approaches to inform future programming.
 Uganda 2024-12-23 11:36:17 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca Nansubuga Kaaya
ID: UNCST-2024-R002104
 Piloting a frugally innovated surgical fracture table in Uganda: Assessing its functionality, usability, and acceptability.
REFNo: SIR454ES

To pilot a frugally innovated surgical fracture table in Uganda and assess its functionality, usability, and acceptability in resource-limited healthcare settings through:
1. To evaluate the functionality of the frugally innovated surgical fracture table selected healthcare professionals by assessing its ability to: securely position patients, allow for stable positioning and smooth adjustment of the tentative limb position.
2. To assess the usability of the surgical fracture table selected healthcare professionals by measuring: the time required for set-up, the perceived ease of use of the table, the perceived comfort levels during manipulation.
3. To determine the acceptability of the surgical fracture table among selected healthcare professionals by assessing: their overall satisfaction with the table's design, functionality, and usability, willingness to recommend or use the table in their clinical practice and their perceptions of the table's potential impact on patient outcomes and safety

 Uganda 2024-12-23 11:35:30 2027-12-23 Engineering and Technology Non-Clinical Trial Non-degree Award
Afiz Kibuuka Kibuuka
ID: UNCST-2021-R012755
 A phase III, Multicenter, Randomized, Placebo Controlled, Double blind Study to Assess Efficacy and Safety of Crizanlizumab (5 mg/kg) versus placebo, with or without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients with Frequent Vaso-Occlusive Crises
REFNo: HS5365ES

To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of VOCs* that are healthcare professional (HCP)-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) over the planned 52-week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in 12 months prior to the screening visit).
To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of all VOCs including VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) and VOCs that are self-managed without recommendations from HCP during the event over the planned 52 week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in the 12 months prior to the Screeening visit
To evaluate the annualized rate of VOCs by type of management between treatment arms over the planned 52-week treatment period: • VOCs that are HCP-managed at a health care facility • VOCs that are HCP-managed via remote consultation • VOCs that are self-managed without recommendations from HCP during the event • VOCs that are HCP-managed via remote consultation or self-managed without recommendations from HCP during the event
To evaluate the time to first VOC that is HCP managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.
To evaluate the proportion of participants free from VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.
 Uganda 2024-12-23 11:34:49 2027-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
Wakib Bunnya
ID: UNCST-2024-R016233
 An analysis of youth participation in elections
REFNo: SS3488ES

Three key objectives guide the research: first, to examine the role of voter education in shaping youth participation; second, to analyze the inclusion of young women and youth with disabilities in elections; and third, to explore the role of youth in peacebuilding and election-related violence.
Uganda 2024-12-23 11:32:13 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Spencer  Birungi
ID: UNCST-2024-R003017
 TRANSBOUNDARY MIGRATION SURVEILLANCE CONTROLS AND THE INFECTIOUS DISEASES MONITORING MECHANISMS: THE CASE OF WEST NILE UGANDA-DEMOCRATIC REPUBLIC OF THE CONGO
REFNo: SS3504ES

1. To describe the transboundary migration patterns along the West Nile Uganda – DRC borderline
2. To explore the transboundary migration infectious disease monitoring in practice along the West Nile Uganda –DRC borderline
3. To establish the association between the transboundary migration surveillance controls and the practices in monitoring of infectious diseases at border points; of entry
4. To describe the adherence to protocols for infectious disease monitoring before, during and after the outbreaks at border points of entry


 Uganda 2024-12-23 11:29:01 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
MARGARET NAKATO
ID: UNCST-2024-R002167
 LIBRARY SERVICE QUALITY AND USER SATISFACTION AMONG GRADUATE STUDENTS IN THE FACULTIES OF SCIENCE AND ENGINEERING AT KYAMBOGO UNIVERSITY, UGANDA
REFNo: SS3545ES

The objectives of the study are to:
1. Establish the effect of tangibility on graduate students' satisfaction with library services at Kyambogo University.
2. Determine the effect of reliability on graduate students' satisfaction with library services at Kyambogo University.
3. Examine the effect of empathy on graduate students' user satisfaction with library services at Kyambogo University.
4. Establish the effect of responsiveness on graduate students' user satisfaction with library services at Kyambogo University.
5. Determine the effect of assurance on graduate students' user satisfaction with library services at Kyambogo University.
6. Develop a framework for measuring library service quality at Kyambogo university
 Uganda 2024-12-23 11:27:18 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Lily Bastian R
ID: UNCST-2024-R002139
 A Mixed Methods Study on Psychosocial and Health Practices Among Young People Living with HIV (YPLHIV) in Kampala, Uganda
REFNo: HS5354ES

The objective of this study is to assess the impact of resilience on sexual practices, behaviors, and health-related outcomes among young people living with HIV (YPLHIV) in Kampala, Uganda.
 USA 2024-12-23 11:24:59 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
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