Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Peter Olds
ID: UNCST-2023-R006240
Developing Better Control Together, a multi-faceted patient-support group for patients with hypertension in Uganda
REFNo: HS5309ES

We propose to develop a multi-faceted patient-support group for patients living with HTN in rural Uganda using an iterative approach that is tailored to the local context. We will adapt several evidence-based interventions for patient-support groups from the HIV experience to develop a comprehensive intervention for patients with HTN by including aspects of disease education, social support, financial activities, and bulk purchasing of HTN medications.
USA 2025-01-22 16:51:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Rwankangi
ID: UNCST-2024-R016056
Solar-Powered Irrigation Schemes for Smallholder Farmers in Uganda: Assessing Impact and Sustainability
REFNo: SIR452ES

1. To examine the impact of adopting solar-powered irrigation systems on crop
yields in horticulture among smallholder farmers in eastern Uganda.

2. To examine how farmers’ knowledge and skills in operating and maintaining
solar irrigation systems influence the adoption of solar-powered irrigation
technology among smallholder farmers.

3. To analyze the effect of stakeholder engagement on the adoption of solar-
powered irrigation technologies among smallholder farmers.

4.To assess how the Ugandan Government’s policy frameworks influence, the
adoption of solar-powered irrigation technology among smallholder farmers.

Uganda 2025-01-22 16:49:32 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
Functional Role, Temporal Dynamics, and Protective Impact of IgA on Clinical Outcomes in Uncomplicated Plasmodium falciparum Malaria
REFNo: HS5353ES

General Objective
To investigate the functional role, temporal dynamics, and protective impact of IgA on clinical outcomes in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda.
Specific Objectives
1. To quantify the functional activity of serum IgA antibodies in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda, by measuring the percentage reduction in hepatocyte infection, the inhibition of merozoite invasion of erythrocytes, and the level of neutrophil activation through oxidative burst and cytokine release.
2. To characterize the temporal dynamics and persistence of IgA responses in adult patients with uncomplicated malaria in the greater Kampala region over a 42-day follow-up period, by measuring peak IgA levels (C_max), time to peak level (T_max), rate of decline (IgA half-life), and area under the curve (AUC).
3. To evaluate the association between serum IgA levels and clinical outcomes in adult patients with uncomplicated malaria in the greater Kampala region, by assessing symptom resolution time and parasite clearance time.
4. To determine the correlation between IgA levels and complement activation, as well as their association with pro-inflammatory or regulatory cytokines during and after Plasmodium falciparum infection in adult patients with uncomplicated malaria in the greater Kampala region, Uganda.

Uganda 2025-01-22 16:47:42 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dina Nabasumba
ID: UNCST-2023-R006504
Crop production dynamics and vulnerability to food insecurity in the face of climate variability: A case of smallholder farmers in south-western Uganda
REFNo: A524ES

4. To classify the extent and factors controlling the influence of climate variability on vulnerability to food insecurity among smallholder farmers in south-western Uganda,3. To determine the influence of spatial-temporal rainfall variability on adoption patterns of land-based climate smart agricultural practices in seasonal cropping systems of smallholder farmers in south-western Uganda ,2. To establish the relationship between smallholder farmers’ knowledge, attitudes and adoption of climate smart agricultural practices in south-western Uganda,1. To assess smallholder farmers’ perceptions of climate variability and the extent to which it has altered crop selection and cultivation patterns in south-western Uganda,To establish the influence of climate variability on the crop production systems and vulnerability to food insecurity among smallholder farmers in south-western Uganda,
Uganda 2025-01-22 16:46:28 2028-01-22 Agricultural Sciences Non-Clinical Trial Degree Award
Chikadibia Uche Kalu Awa
ID: UNCST-2024-R003818
OPTIMIZATION OF MIX DESIGN FOR STRUCTURAL LIGHTWEIGHT CONCRETE (SLWC) WITH ARTIFICIAL AGGREGATES USING RESPONSE SURFACE METHODOLOGY
REFNo: SIR344ES

1. To produce and characterize artificial aggregates from polyethylene terephthalate plastic waste.
2. To design experimental mixture proportions for S.L.W.C. using mathematically independent variable (factorial) approach.
3. To evaluate the performance of S.L.W.C. regarding density, splitting tensile strength, compressive strength, workability, and durability.
4. To apply response surface methodology for the analysis of the obtained results to derive model equations for each performance criteria.
5. To optimize (S.L.W.C.) using desirability function.
6. To carry out microstructural analysis of the specimens.

Nigeria 2025-01-22 16:45:23 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
SIMON MUCHURO
ID: UNCST-2024-R003624
Estimation of TB notification rates among healthcare workers in 2023 and assessment of associated healthcare worker and health facility characteristics
REFNo: HS5200ES

Primary objective:
1. To establish the TB notification rates among healthcare workers
2. To establish the risk factors associated with TB disease
Secondary objectives:
3. To determine TB treatment outcomes among healthcare workers started on drug sensitive TB treatment from 1st January to 31st December 20
Uganda 2025-01-22 16:44:20 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Muwonge Ssajjabbi
ID: UNCST-2023-R007179
AN INVESTIGATION INTO THE IMPACT OF TELEMEDICINE ON PATIENT OUTCOMES IN KAMPALA DISTRICT. A CASE OF RUBAGA DIVISION
REFNo: HS4901ES

iii. To investigate the extent to which telemedicine improves patient satisfaction for patients in Lubaga division. ,ii. To assess the impact of telemedicine on accessibility of health care services for patients in Lubaga division. ,i. To identify the barriers and facilitators of telemedicine adoption and how they impact patient outcomes in Lubaga division. ,To investigate the impact of telemedicine on patient outcomes in Kampala district, with emphasis on Lubaga division so as to improve the quality of health-care service delivery.,
Uganda 2025-01-22 16:38:30 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
ROSE AKULLO
ID: UNCST-2024-R005155
LEADERSHIP BEHAVIOR IN MANAGEMENT OF CURRICULUM CHANGES IN THE LOWER SECONDARY SCHOOLS IN KARAMOJA REGION, NORTH EASTERN UGANDA.
REFNo: SS3120ES

5. Determine the mediating effect of organizational climate on the relationship between leadership behaviours and curriculum change management in the lower secondary curriculum,4. To assess the impact of leadership behaviour on the level of teacher support for curriculum change management in lower secondary schools in the Karamoja Region, Uganda.,3. Establish the effect of change-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja ,2. Assess the effect of task-oriented leadership behaviours on management of curriculum changes in lower secondary schools in the Karamoja Region, Uganda.,1.Examine the effect of relation-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja,To investigate the effect of leadership behaviors on management of curriculum changes in secondary schools in Karamoja region, North Eastern Uganda.,
Uganda 2025-01-22 16:33:52 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
BONIFACE OJOK
ID: UNCST-2023-R006075
Lok Ber Bedo Study: Storytelling with young people affected by conflict in Acholi sub-region, northern Uganda
REFNo: SS3437ES

1. General objective: The proposed project seeks to engage groups of young people affected by conflict in Acholi sub-region to explore the extent to which storytelling can be harnessed to promote shared understanding of the wholesome character of ber bedo (Acholi meaning 'wellbeing) and collective action to advance ber bedo.

2. Specific objectives
(1) To explore conflict affected young people’s understanding of ber bedo and practice of storytelling in Acholi sub-region.
(2) To identify challenges to ber bedo among young people affected by conflict in Acholi sub-region and to explore existing and potential strategies to address these.
(3) To assess to what extent the 'lok ber bedo' (Acholi meaning 'let's talk well-being') storytelling approach can be transformational, in its various dimensions, for young people affected by conflict in Acholi sub-region.
Uganda 2025-01-22 16:24:55 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nabusige Gesa Jean Brenda
ID: UNCST-2024-R005397
Acaricide exposure and associated genotoxicity in farmers of the cattle corridor: a case study of Kiruhura district
REFNo: HS5250ES

To determine oxidative stress, inflammatory and genotoxicity outcomes among pesticide exposed farmers and establish their relationship with pesticide exposure.,To quantify residues of selected pesticides in raw cows milk and open well water, as well as human and animal serum and determine factors associated with these residue levels. ,To assess Knowledge, Attitudes, and Practices towards pesticide use and factors associated with variations therewith among farmers.,To investigate farmers Knowledge, Attitudes and Practices towards pesticide use, farm ecosystem exposure, associated outcomes to human health and genotoxicity among pesticide exposed farmers.,
Uganda 2025-01-22 15:51:36 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Elly Atuhumuza
ID: UNCST-2024-R002706
Assessing Effectiveness of Interpersonal Group Therapy for Depression on Academic Performance in Ugandan Schools
REFNo: SS3249ES

To describe the feasibility and acceptability of implementing IPT-G within the school setting,To determine the effects of IPT-G on the academic performance of students by measuring improvements in grades, attendance, and overall academic engagement.,To determine the effects of Interpersonal Group Therapy (IPT-G) on reducing depressive symptoms among school-aged adolescents in Uganda. ,The general objective is to evaluate the effectiveness of Interpersonal Group Therapy (IPT-G) in improving the mental health and academic performance of students in Ugandan schools.,
Uganda 2025-01-22 15:47:24 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richardson Mafigiri
ID: UNCST-2024-R003907
HEALTH WORKERS PRACTICES AND PERFORMANCE OF HEALTHCARE PROJECTS IN KAYUNGA DISTRICT, UGANDA
REFNo: SS3194ES

iv. To examine the relationship between policy support and performance of health projects in Kayunga district,iii. To establish practical strategies to improve Performance of health projects in Kayunga District ,ii. To examine the effect of vaccine management by health workers on Performance of health projects in Kayunga District.,i. To determine the effect of surveillance practices by health workers on Performance of health projects in Kayunga District.,The purpose of the study will be to assess the effect of health workers’ practices on performance of health projects in Uganda,
Uganda 2025-01-22 15:42:36 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Juma Said Tusubila
ID: UNCST-2024-R005319
Using Photovoice to examine the burden and experiences of refugee caretakers of children with special health care needs in Rhino Camp refugee settlement in West Nile, Uganda
REFNo: HS5441ES

● To explore the physical, emotional, and financial challenges (burden) faced by refugee caretakers of CSHCN in Rhino Camp Refugee Settlement, West Nile ● To understand the coping mechanisms and resilience of refugee caretakers in of CSHCN in a refugee settlement in Rhino Camp refugee settlement, West Nile. ● To generate insights on the support systems, barriers, and facilitators to improve the well-being of caretakers of CSHCN in a refugee settlement in Rhino Camp refugee settlement, West Nile.
Uganda 2025-01-22 15:08:17 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
‘5 Rs to Rescue’ A quality improvement initiative with a cluster trial evaluation and embedded process evaluation
REFNo: HS5020ES

To evaluate the effect of the QI intervention on: 1. 30 day in-hospital mortality. 2. Duration of hospital stay.,To evaluate whether implementation of the ‘5 Rs to Rescue’ quality improvement intervention increases surveillance for patients at risk of ‘failure to rescue’ after surgery in hospitals in Africa.,
UK 2025-01-22 12:30:25 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Immaculate  Nankya Lillian
ID: UNCST-2020-R014784
Interplay between Estrogen, immune activation and HIV persistence during pregnancy
REFNo: SS3319ES

To characterize the clonal dynamics and diversity within the circulating latent reservoir in pregnant women on ART who are experiencing low-level viremia, viral blips, and persistently non-suppressed virus. ,To measure fluctuations in inflammation and immune activation markers, estrogen, and reservoir dynamics in women during pregnancy. , The main goal of this protocol is to understand the interplay between estrogen, markers of immune activation and the reservoir dynamics among pregnant women.,
Uganda 2025-01-22 11:58:29 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
Comparing in-person versus virtual postoperative review appointments for children following guided growth surgery at CORSU Hospital, Uganda
REFNo: HS5268ES

Study Objectives
Primary objectives
To compare the show-rates of in-person versus virtual/telehealth post-operative review appointments for children following guided growth surgery at CoRSU Hospital

Secondary objectives.
1.To compare parental satisfaction of in-person versus virtual appointments
2.To determine the factors that facilitate in-person and virtual appointments following guided growth surgery.
3.To compare the rate of post-operative complications following in-person follow-up versus virtual follow-up
Uganda 2025-01-22 10:12:27 2028-01-22 Medical and Health Sciences Clinical Trial Non-degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
GENERATING LOCAL DATA ON HPV VACCINATION IMPACT AND TRAINING NEEDS AT THE LEVEL OF VACCINE IMPLEMENTERS – A FEASIBILITY STUDY
REFNo: HS5219ES

1) generate local data on HPV vaccine induced immune response and HPV infection prevalence using first-void urine (FVU) in Uganda and assess feasibility of conducting such studies, 2) assess knowledge and training gaps among HCWs in Uganda and standardize HPV vaccine training barometer survey,
Uganda 2025-01-22 10:09:20 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MUSANA SAMSON ISRAEL
ID: UNCST-2024-R016481
RELIGIOUS MISSION FIELD RIVALRIES AND ITS IMPACT ON CHRISTIAN-MUSLIM PEACEFUL COEXISTENCE IN MBALE CITY, UGANDA
REFNo: SS3541ES

1) to investigate the root causes of religious mission field rivalries affecting Christian-Muslim peaceful coexistence. 2) to establish Christian and Muslim missionary methods being utilised in the
mission field; and 3) to ascertain the impact of Christian and Muslim missionary outreach
practices.
Uganda 2025-01-10 12:29:51 2028-01-10 Social Science and Humanities Non-Clinical Trial Degree Award
Venantius Bbaale Kirwana Bbaale
ID: UNCST-2024-R002370
Behind the Scenes: Young women and gender-based inequities in Africa’s Creative Sector -Uganda research project
REFNo: SS3483ES

iii. Provide evidence-based recommendations and best practices for key stakeholders that can support gender equity in Uganda\'s creative industries and workplaces.,ii. Map the Creative Sector in Uganda to understand its organization in terms of stakeholders, policies, potential, remuneration systems, accessibility to different categories of youth, challenges, conduct codes, job creation opportunities, funding, education, training, products, and services.,i. To generate and disseminate evidence on the nature, dynamics, and implications of gender-based inequities faced by young female creatives in Uganda and other countries in the project.,
Uganda 2025-01-10 12:12:15 2028-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Justine Namuli Diana
ID: UNCST-2021-R011844
ENHANCING COMPREHENSION OF INFORMED CONSENT IN RESEARCH INVOLVING PATIENTS WITH PSYCHOTIC DISORDERS USING AUDIO-VISUAL AIDS
REFNo: HS5358ES

To evaluate the comprehension of informed consent, identify key factors that are associated with comprehension of consent, determine the feasibility, acceptability, and preliminary effectiveness of audio-visual aids on enhancing the comprehension of consent information during the consenting process in research involving individuals with psychotic disorders
Uganda 2025-01-10 12:00:57 2028-01-10 Medical and Health Sciences Clinical Trial Degree Award
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