Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Elly Atuhumuza
ID: UNCST-2024-R002706
 Evaluating the Effects of StrongMinds Commu-nity-Based Group Interpersonal Therapy on De-pression and Secondary Outcomes in Uganda: A Randomized Controlled Trial
REFNo: SS3945ES

This study aims to evaluate the impact of the StrongMinds IPT-G model in reducing depressive symptoms and improving secondary outcomes related to quality of life and labour supply. The study also seeks to assess the feasibility of delivering a compressed six-week IPT-G intervention in a programmatic setting. Additionally, as this is a pilot RCT, this study will inform the proto-cols, outcome metrics and optimal design of an eventual larger-scale efficacy study.
Uganda 2025-07-10 13:30:00 2028-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Arinaitwe lucian
ID: UNCST-2025-R018143
 THE CONTRIBUTION OF OBUNTU TOWARDS PEACE-BUILDING IN KIGEZI-UGANDA
REFNo: SS4019ES

1. To investigate Obuntu philosophies in terms of ethical values espousing contribution towards peace-building efforts, in Kigezi region 2. To assess the Obuntu-peace implementations, in terms of what is done, up to the grassroots levels 3. To determine the leading factors responsible in unraveling conflicts thereof
 Uganda 2025-07-10 13:28:08 2028-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Stephen Oupal
ID: UNCST-2024-R003568
 Baseline for Uganda Refugees Resilience Initiative Project
REFNo: A609ES

I. To establish the baseline values of the log frame indicators on outcome and output level in accordance with the two consortia (DRC and SCI) project Log frames.
II. To provide context information about the project’s relevant thematic areas through qualitative interviews.

 Uganda 2025-07-10 13:25:48 2028-07-10 Agricultural Sciences Non-Clinical Trial Non-degree Award
Jane Patricia Bako
ID: UNCST-2025-R017603
 ASSESSMENT OF UGANDA’S LEGAL AND POLICY FRAMEWORK FOR THE MENTAL HEALTH AND WELL-BEING OF LEGAL PROFESSIONALS
REFNo: SS3968ES

1. Examine the mental health and well-being challenges of legal professionals in Uganda
2. Assess how the theoretical frameworks can help to understand these challenges
3. Examine how mental health challenges affect the performance of legal professionals and the justice ecosystem in Uganda
4. Establish how the mental health and well-being of legal professionals in Uganda can be improved.

 Uganda 2025-07-10 13:20:18 2028-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Gloria Kaudha
ID: UNCST-2025-R017148
 Assessing the clinical practices of primary Health Care Workers in evaluating children presenting with acute respiratory symptoms and skin infections at Health Center IVs and IIIs in Kampala, Uganda.
REFNo: HS6119ES

General Objective:
To Assess the clinical practices of primary Health Care Workers evaluating children presenting with acute respiratory symptoms and skin infections in Kampala, Uganda.

Specific Objectives:
1.To assess the clinical practices (history, physical examination, investigations and treatment) of health care workers in evaluating children with acute respiratory symptoms and skin infections in Kampala, Uganda.
2.To describe the facilitators and barriers to the clinical practices including treatment given to children with acute respiratory symptoms and skin infections

 Uganda 2025-07-10 13:17:46 2028-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bongomin Joachim
ID: UNCST-2025-R017414
 GROUNDWATER POTENTIAL MAPPING USING HYDROLOGIC, DROGEOLOGIC AND STRUCTURAL MODELS IN TOCHI WATERSHED (UGANDA)
REFNo: SIR527ES

General objective
To develop methodology for delineation of groundwater recharge zone using hydrologic,
hydrogeologic and structural models.

Specific objectives
1. To develop groundwater flow map within the vadose zone using SWAT model.
2. To develop groundwater table profile for the watershed.
3. To generate litho-stratigraphic pile potential to transmit groundwater.
4. To delineate groundwater potential in Tochi watershed.

Uganda 2025-07-10 13:14:02 2028-07-10 Engineering and Technology Non-Clinical Trial Degree Award
Charlotte Brown Louise
ID: UNCST-2021-R012078
 Plants, Toxicity and Science at African Borderlands: Cassava\'s Ambivalent History in West Nile, Uganda
REFNo: SS3980ES

To support the profile of situated knowledge in discussions of agricultural change,To contribute social science evidence to African Environmental Health,To contribute to debates within Geography concerning agricultural development,To understand the changing relationship of agricultural farmers to cassava in West Nile, Uganda,
 UK 2025-07-10 13:12:43 2028-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Tumwebaze G Godfrey
ID: UNCST-2024-R002158
 AN INTEGRATED MOBILE COMMUNICATION FRAMEWORK FOR ENHANCING LIVESTOCK DISEASES MANAGEMENT AND ADVISORY SERVICES
REFNo: SIR490ES

Main Objective 1. The overall goal is to enhance the monitoring, controlling and management of livestock diseases using a comprehensive mobile-based communication framework. Specific Objectives 1. Evaluate the challenges and barriers livestock (cattle) farmers face in managing diseases and accessing advisory services through mobile communication technologies. 2. Develop of an integrated mobile communication framework for enhancing livestock disease management and advisory services. 3. Evaluate the usability, acceptability and effectiveness of the developed framework through the use of a mobile application
 Uganda 2025-07-10 13:06:07 2028-07-10 Engineering and Technology Non-Clinical Trial Degree Award
Cynthia Agema Lysanne
ID: UNCST-2025-R018967
 Exploring the balance between social disappointment and inequity aversion in chimpanzees.
REFNo: NS979ES

The objective of this study is to gain deeper insight into the behavioural responses of chimpanzees to unequal reward distributions, and to examine whether these responses are primarily driven by social disappointment or by inequity aversion. We aim to better understand the cognitive and emotional processes underlying social evaluation in great apes. The study contributes to the scientific understanding of the evolutionary roots of fairness and social expectations, and offers practical value for improving animal welfare, especially in captive or sanctuary settings, by adapting care practices based on species-specific social sensitivity.
 Netherlands 2025-07-10 12:51:39 2028-07-10 Natural Sciences Non-Clinical Trial Degree Award
Martin Kaddumukasa.
ID: UNCST-2024-R003870
 Prospective Global Platform to Evaluate and Enhance Cognitive and Functional Trajectories after Stroke (PROSPECT)
REFNo: HS5743ES

We will identify the natural history and population attributable
risk of key factors for post-stroke cognitive and functional
impairment, including baseline characteristics, details of the index
stroke and post-stroke complications
 Uganda 2025-07-10 12:50:40 2028-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Atwine
ID: UNCST-2019-R012948
 SAFETY AND EFFICACY OF THE PHOTO-KABADA DEVICE AS COMPARED TO DEVICES IN ROUTINE USE IN ADMINISTERING PHOTOTHERAPY FOR BABIES WITH NEONATAL JAUNDICE: AN OPEN-LABEL, RANDOMIZED CONTROLLED CLINICAL TRIAL (MUST-2024-1404).
REFNo: HS5411ES

5) Secondary: To describe the experiences of health workers using the test (Photo-Kabada) and control PT devices and caretakers of children treated with these devices.,4) Secondary: To compare the other safety and efficacy outcomes when babies are treated with Photo-Kabada compared to available phototherapy devices on the neonatal unit of MRRH. ,3) Secondary: To compare the reduction in bilirubin levels per unit time when babies are treated with Photo-Kabada compared to available phototherapy devices on the neonatal unit of MRRH. ,2) Primary: To compare the efficacy of Photo-Kabada phototherapy machine with existing phototherapy machine at selected hospitals in treating neonates with jaundice.,1) Primary: To compare the safety of Photo-Kabada phototherapy machine with existing phototherapy machine at selected hospitals in treating neonates with jaundice.,
 Uganda 2025-07-10 11:09:52 2028-07-10 Medical and Health Sciences Clinical Trial Non-degree Award
SAMANTHA KESHARA
ID: UNCST-2024-R016384
 NEONATAL JAUNDICE MANAGEMENT:ASSESSING THE KNOWLEDGE, ATTITUDES, and PRACTICES(KAP) OF MOTHERS AT KAWEMPE SPECIALISED NATIONAL REFERRAL HOSPITAL (KNRH).
REFNo: HS6108ES

To assess the knowledge, attitudes, and practices (KAP) of mothers regarding neonatal jaundice at Kawempe Specialized National Referral Hospital.

Specific Study Objectives

To evaluate the level of maternal knowledge on neonatal jaundice symptoms, causes, complications, and treatment options.

To assess maternal attitudes and perceptions toward neonatal jaundice and its severity.To examine maternal attitudes and perceptions toward neonatal jaundice and its severity.

To determine the healthcare-seeking practices of mothers when managing neonatal jaundice.To analyze the healthcare-seeking practices of mothers when managing neonatal jaundice.

 Uganda 2025-07-10 11:05:34 2028-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Tumwine Kashugyera
ID: UNCST-2025-R017959
 Understanding and managing fevers from infections spread by animals
REFNo: HS6008ES

1.Determine the common causes of ZAFI and associated factors in paediatric patients living in urban and rural areas of Kabale, Uganda 2.Develop and test novel technologies and approaches for diagnosing ZAFI that are suitable for use in LMIC and field settings 2.1. Evaluate point-of-care (PoC) tests and pilot prototype molecular diagnostic platforms for key zoonotic pathogens 3.Involve communities and the health sector in Kabale, Uganda,in defining improved approaches to diagnosis and management of ZAFI 4.Strengthen capacity and capability for research on diagnosis and management of zoonotic diseases in Kabale, Uganda
 Uganda 2025-07-09 17:55:28 2028-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Constance Buzaare
ID: UNCST-2024-R005359
 Project-Based Learning, Conventional Teaching Approaches and Developing English Language Proficiency among Refugee Learners: A case of Bidi-Bidi refugee settlement
REFNo: SS3988ES

i. To assess the English language proficiency of refugee learners before implementing project-based learning and traditional learning approaches in the Bidi Bidi refugee settlement. ii. To examine the level of English language proficiency of refugee learners after the interventions of project-based learning and traditional learning approaches in Bidi Bidi settlement. iii. To determine the difference in English language proficiency among refugee learners before and after implementing project-based learning, compared to traditional teaching approaches in Bidi Bidi settlement. iv. To assess learners' perceptions of project-based and traditional learning approaches in enhancing English language proficiency among refugee learners in Bid Bidi Settlement.
Uganda 2025-07-09 17:06:10 2028-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Edwin Kigozi
ID: UNCST-2021-R013215
 Exploring the Potential of Graduate Nurses in Uganda to Advance Planetary Health and Foster Climate-Resilient Healthcare Systems.
REFNo: HS6116ES

Main aim.
This study aims to explore the barriers and facilitators for graduate nurses in promoting climate-resilient healthcare systems.

Specific Objectives:
1. To examine how graduate nurses in Uganda are involved in promoting climate-resilient healthcare systems within Uganda’s health sector.
2. To explore how education, training, current roles and work conditions influence the capacity of graduate nurses to engage in climate-resilient healthcare advocacy within and beyond traditional clinical settings.
3. To explore additional needs to support graduate nurses in Uganda to contribute to climate-resilient healthcare systems.

 Uganda 2025-07-09 16:21:41 2028-07-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Esther Cathlyn  Atukunda
ID: UNCST-2022-R009265
 Evaluating Healthy Families PrEP: an intervention to promote PrEP use during periconception, pregnancy and postpartum periods for women in rural Uganda
REFNo: HS6117ES

1. Adapt Healthy Families-PrEP (HF-PrEP) to community clinics in Mbarara and Sheema Districts, Uganda to include postpartum women guided by our conceptual framework and the Consolidated Framework for Implementation Research (CFIR

2. Test Healthy Families-PrEP intervention effectiveness in a cluster-randomized control trial in Ugandan community health centers (HCs)

3. Determine incremental cost-per-person participating in Healthy Families-PrEP and estimate cost-effectiveness per incident HIV infection averted among women and their infants.
 Uganda 2025-07-09 16:14:46 2028-07-09 Medical and Health Sciences Clinical Trial Non-degree Award
LOIS BAYIGGA
ID: UNCST-2024-R004310
 IN VIVO GENE THERAPY: AN HIV CURE IN A SYRINGE
REFNo: HS6079ES

To evaluate the efficacy of the CRISPR/Cas dual guide RNA in curing HIV infection in a humanized immune system,To engineer lipid nanoparticles with receptors for targeting specific cells and tissues,To test the efficacy of CRISPR/Cas in reducing the HIV reservoir in infected cells and tissues from both adult and pediatric populations infected with different HIV subtypes,To evaluate the effectiveness of CRISPR/Cas dual guide RNA in reducing the HIV reservoir and curing HIV infection,
 Uganda 2025-07-08 13:58:37 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ssemanda Ronald
ID: UNCST-2025-R019141
 Tax Type Dynamics, Filler's Perceptions, and Filing Compliance: An Empirical Study of Uganda's Public Sector
REFNo: SS4032ES

To thoroughly examine tax filing compliance in Uganda's public sector, this study will aim to achieve the following Specific Objectives:
1. To examine the effect of Income Tax on filing compliance within Uganda’s public sector.
2. To assess the effect of Value Added Tax (VAT) on filing compliance within Uganda’s public sector.
3. To analyze the effect of Pay-As-You-Earn (PAYE) on filing compliance within Uganda’s public sector.
4. To evaluate the effect of Withholding Tax (WHT) on filing compliance within Uganda’s public sector.
5. To develop a model to enhance tax compliance in public organizations by addressing tax filers' perceptions across various tax types.
 Uganda 2025-07-08 11:24:40 2028-07-08 Social Science and Humanities Non-Clinical Trial Degree Award
Ivan Segawa
ID: UNCST-2021-R012795
 Optimizing Community-Pharmacy PrEP Delivery for Cisgender Female Sex Workers in Uganda
REFNo: HS6178ES

Aim 1: Compare the potential reach and accessibility of PrEP services through community retail pharmacies and PrEP facilities in Kampala. Aim 2: Evaluate pharmacy capacity and staff perspectives on delivering PrEP through community retail pharmacies in Kampala.
Uganda 2025-07-08 11:22:09 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Assessment of Pharmacovigilance Systems, Knowledge and Reporting in public health facilities. A Cross-sectional Assessment
REFNo: HS6195ES

i) To evaluate functionality of PV systems in public health facilities in Uganda. ii) To evaluate current PV knowledge at public health facilities in Uganda. iii) To establish evaluate the current pharmacovigilance reporting rates in public health facilities in Uganda. iv) To establish the factors influencing pharmacovigilance knowledge among health facilities practitioners in public health facilities in Uganda. v) To establish the factors influencing the reporting rates of ADRs/AEFI in public health facilities in Uganda.
Uganda 2025-07-08 11:17:16 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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