Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,902
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isaac Ssewanyana
ID: UNCST-2020-R014336
STANDARDTM M10 HR-HPV: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS6022ES

Demonstration of usability of the STANDARDTM M10 Hr-HPV assay. ,Demonstration of sample type equivalence for the STANDARDTM M10 Hr-HPV assay: ThinPrep® PreservCyt® Solution (Hologic) vs. BD SurePathTM Collection Vial (Becton, Dickinson and Company),Determination of the relative diagnostic sensitivity and specificity i.e. compared with the Roche Cobas HPV assay (used according to the current standard of care at the study site).,Determination of clinical accuracy i.e. absolute diagnostic sensitivity for CIN2+ and CIN3+ and absolute diagnostic specificity for ≤ CIN1.,To demonstrate the clinical performance of the STANDARDTM M10 Hr-HPV assay when used by healthcare professionals in a laboratory setting or health institution (i.e. intended use setting), the following objectives have been defined.,
Uganda 2025-05-29 17:19:03 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anatoli Mawanda
ID: UNCST-2024-R015927
GENETIC AND MOLECULAR DETERMINANTS OF BREAST CANCER DISPARITY AMONG AFRICAN, AFRICAN AMERICAN AND WHITE POPULATIONS
REFNo: HS6015ES

To study the genetic, molecular, and biological regulators of breast cancer in Ugandan
women and compare them with African American and white women.
Uganda 2025-05-29 17:17:31 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christabel Gero Anyango
ID: UNCST-2025-R017108
Perspectives of Child Domestic Workers and Their Employers: A Qualitative Study in Kampala, Uganda
REFNo: SS3860ES

• To establish patterns of entry into, exit out of and conditions of child domestic work in the Ugandan setting, including patterns that constitute human trafficking. Entry patterns will include decision making and influences to enter domestic work, while exit will encompass strategies used to transition to other work roles and the types of work roles entered following domestic work. • To understand employers’ perceptions of and views on child domestic workers, including reasons for recruiting younger workers, strategies to recruit CDWs, views on the benefits, drawbacks and development needs of younger workers, treatment and remuneration of CDWs, and awareness of laws and policies related to young workers, among others.
Kenya 2025-05-29 17:15:05 2028-05-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jeya Sushimitha Jawahar Kanth
ID: UNCST-2024-R016269
Evaluating the Impact of Social Media Influencers on Tobacco Use Among Urban Youth in Africa: A Comparative Mixed Methods Study Across Kampala, Nairobi, and Lagos
REFNo: SS3850ES

Main Objective
1. To explore and compare the role of social media influencers in shaping tobacco use behaviors among urban youth (ages 18-29) residing in Kampala, Nairobi, and Lagos by examining tobacco use prevalence, influencer messaging, and youth perspectives.
Specific Objectives
1. To determine the prevalence of tobacco use among urban youth (18-29 years) in Nairobi, Lagos, and Kampala.
2. To assess the relationship between exposure to influencer content and tobacco use behaviors among urban youth.
3. To analyze the content and reach of pro-tobacco messages shared by social media influencers among the target youth population.
4. To investigate urban youth perceptions of how influencers impact their decisions and attitudes toward tobacco use.
India 2025-05-29 17:14:22 2028-05-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Denis Nansera
ID: UNCST-2024-R004002
Improving HIV testing among Children under five in Rural Uganda
REFNo: HS5829ES

The main objective of this study is to develop a traditional healer facilitated paediatric HIV testing program to improve access to paediatric HIV testing. To do this, we will first use qualitative study methods to determine factors that influence HIV testing among paediatric clients of TH and guide adaptation of the TH-facilitated HIV testing program for children. We will then implement a pilot study to evaluate offering paediatric HIV testing at traditional healer locations in southwestern Uganda.
Uganda 2025-05-29 17:12:49 2028-05-29 Medical and Health Sciences Clinical Trial Non-degree Award
Nanyonga Elizabeth Monica
ID: UNCST-2025-R018232
srd
REFNo: SIR516ES

GGGGGGGGGGGGGGGGGGGGGGGGGGGG
Uganda 2025-05-27 9:30:38 2028-05-27 Engineering and Technology Clinical Trial Non-degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
“Exploring Acceptability: Expanding Family Planning Services in Pharmacies and drug shops in Uganda.”
REFNo: HS5733ES

a. To assess the acceptability of family planning including implant provision through pharmacies and drug shops among key stakeholders in Uganda.
b. To examine the role of non-monetary incentives (e.g., training, certification, recognition) in motivating pharmacy and drug shop operators to provide FP services.
c. To explore the willingness and capacity of pharmacy and drug shop providers to comply with government reporting requirements for FP service provision.
d. To identify perceived potential facilitators and challenges to the successful implementation of implant provision in pharmacies and drug shops in Uganda.

Uganda 2025-05-27 11:03:29 2028-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martina Ferracane Francesca
ID: UNCST-2025-R016796
Assessing the digital trade rules in Rwanda and Uganda
REFNo: SS3942ES

Main Objective 1. Address the knowledge gap between Uganda’s current legal framework and its potential enabling or restrictive impact on digital trade development, ensuring that policy initiatives and policy framework align with the needs of businesses engaging in digital trade. Specific Objectives 1. Identify the challenges faced by private sector entities, including SMEs and start-ups, in digital trade. 2. Provide actionable policy recommendations to improve Uganda’s digital trade framework. 3. Assess the existing digital trade policies in Uganda and identify areas for improvement.
Italy 2025-05-23 8:20:18 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Lwasa
ID: UNCST-2025-R018323
Value Chain Study and Market Assessment Farmer Managed Natural Regeneration (FMNR) Catalyst Project
REFNo: A607ES

The main objective of the value chain and market analysis was to identify complementary livelihood options or enterprises in FMNR project implementation areas that can be established in the demonstration and learning sites.
Uganda 2025-05-23 14:12:56 2028-05-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
DARIUS OWACHI
ID: UNCST-2022-R009373
Impact of Antimicrobial Stewardship Interventions on Healthcare Workers’ Antibiotic Prescription Patterns and Compliance with Standard Treatment Guidelines at Kiruddu Hospital; A Quality Improvement Study.
REFNo: HS5989ES

To assess the impact of antimicrobial stewardship interventions on the knowledge levels, antibiotic prescription patterns and compliance to standard treatment guidelines, by healthcare workers at Kiruddu National Referral hospital through quality improvement methods. ,
Uganda 2025-05-23 14:10:37 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet  Gwokyalya
ID: UNCST-2022-R010490
Drivers of under-prescription of cervical cancer screening: evidence from Uganda
REFNo: HS5957ES

Main Objective
1. To quantify the drivers of under-prescription of cervical cancer screening among providers of routine care in Uganda
________________________________________
Specific Objectives
1. To evaluate whether providers lack knowledge of recommended cervical cancer screening practices
2. To identify patient characteristics that predict screening recommendation for cervical cancer.
3. To evaluate whether providers with appropriate knowledge of cervical cancer screening recommend screening to their clients (i.e., whether a know-do gap exists).

Uganda 2025-05-23 14:05:07 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
Analysing HIV-1 Reservoir Kinetics, and Host Immune Interactions among non-B subtypes.
REFNo: HS5936ES

General Objective

To understand the dynamics of HIV-1 reservoirs and host immune interactions among non-B subtypes infected participants in Uganda.

Specific objectives:
1. To compare the dimensions of the HIV-1 reservoir among Ugandans, including individuals with high viral loads at the start of ART, and those who have been on ART for varying durations.
2. To detect HIV-1 viral properties associated with latent reservoirs across HIV-subtypes, examining how these patterns may differ and contribute to disparities in reactivation tendencies in Uganda.
3. To detect immune correlates in relation to host characteristics, including HIV-1 specific, B-cells, innate immune cells, CD4 and CD8 cell lineage activation, and exhaustion markers.
4. To develop a supervised machine learning algorithm to predict the HIV-1 latent reservoir behaviours in Uganda.

Uganda 2025-05-23 14:00:42 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Nalikka
ID: UNCST-2024-R016316
Ecological and epidemiological dynamics of viruses in Ugandan bat populations.
REFNo: NS969ES

1. To determine the prevalence, diversity and genetic variation of viruses in different bat species, considering both time and space.
2. To use host density, distribution, and pathogen prevalence to develop models that can be used to forecast spillover risks from bats to other animals, including humans.
3. To investigate the duration of immunity to viruses in bats by sampling individuals across different age groups over time.

Uganda 2025-05-23 13:58:46 2028-05-23 Natural Sciences Non-Clinical Trial Degree Award
Muge Cevik
ID: UNCST-2022-R011548
Improving surveillance and detection of MPXV in Uganda
REFNo: SS3940ES

• To determine seroprevalence of MPXV among people living with HIV in Uganda • To elucidate the risk factors associated with infection.
UK 2025-05-23 13:57:06 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
ochuga patrick olanya
ID: UNCST-2024-R015276
PREVALENCE, AND FACTORS ASSOCIATED WITH CHORIOAMNIONITIS AMONG WOMEN ADMITTED WITH PPROM AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5949ES

To determine the prevalence and factors associated with chorioamnionitis among women admitted with PROM at MRRH
Uganda 2025-05-23 13:54:31 2028-05-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Nina Rugambwa Olivia
ID: UNCST-2019-R000213
SAFEGUARDING MENTAL HEALTH OF CHILDREN WITH PHYSICAL DISABILITIES IN INCLUSIVE PUBLIC PRIMARY SCHOOLS: A CASE OF KAMULI DISTRICT, UGANDA
REFNo: SS3894ES

To explore the coping strategies of children with physical disabilities and their relationship to mental well-being in schools in Kamuli District.,3. To examine mental health safeguarding measures and their implementation in inclusive government primary schools in Kamuli District ,2. To document cultural beliefs and practices that promote mental health and inclusiveness of children with disability at school and in their communities in Kamuli District,1. To determine the mental health status of children with physical disabilities in government-inclusive primary schools in Kamuli district,This study seeks to create awareness about the mental health of children with disabilities and enhance their safety in inclusive government primary schools in Kamuli district.,
Uganda 2025-05-23 13:43:10 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Phiona Bukirwa
ID: UNCST-2022-R009880
Colorectal Cancer Biology: Clinicopathologic characteristics, Mismatch Repair (MMR) status and prognostic factors of colorectal carcinoma in Sub-Saharan Africa
REFNo: HS5980ES

1. To determine the prevalence of Mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
2. To assess the association between histopathological parameters like tumor grading, tumor type, frequency of tumor infiltrating lymphocytes and tumor budding in microsatellite instability-high (MSI-H) FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
3. To assess the association of clinical finding (age, sex, TNM stage, site of tumour) with mismatch repair status in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
4. To assess the prevalence of BRAF and KRAS mutation in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.

Uganda 2025-05-23 13:40:32 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey Kubiriza Kawooya
ID: UNCST-2024-R003138
Eco-innovative technologies for improved nutrition, sustainable production and marketing of Agro-ecological food products in Africa (INNOECOFOOD)
REFNo: A574ES

Main objective of the baseline study
The main objective of the baseline study is to scope community indigenous knowledge, gaps, attitudes and aquaculture practices in local lakes and rivers (living labs) on production, processing, marketing and consumption of aquaculture value chains (fish and selected Spirulina species) and insect species in Uganda.

Specific Objectives
i.To determine the current community Knowledge on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
ii.To determine the current community Attitude on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iii.To determine the current community Practices on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iv.Assess how socio-demographics factors influence the production, processing and consumption of fish, spirulina and insects as food and feed.

Uganda 2025-05-23 13:39:33 2028-05-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
Genetic Associations of INfertility in Africa (The GAIN Study)
REFNo: HS5967ES

The GAIN study aims to identify genetic variants associated with unexplained primary infertility in African women
Uganda 2025-05-23 13:37:00 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
Uganda Population-based HIV Impact Assessment (UPHIA 2024-2025)
REFNo: HS5817ES

The primary objectives of UPHIA 2024-2025 are to:
1) Estimate the national and regional prevalence of HIV viral load suppression (VLS – defined as HIV RNA <1000 copies/milliliter(mL) in adults ages 15 years or older in the general population.
2) Estimate the prevalence of HIV at the national and regional level
3) Assess progress towards the UNAIDS 95- 95- 95 targets at the national and regional level

The secondary objectives of the survey are to:
1) Estimate the HIV incidence at the national level
2) Estimate the prevalence of HIV-related risk behaviors, knowledge, and attitudes
3) Establish the behavioural and demographic determinants of HIV prevalence and incidence
4) Determine the exposure to, uptake of and barriers to access to HIV-related services
5) Estimate the prevalence of elevated blood pressure, elevated blood glucose and obesity among the general population and people living with HIV
6) Assess the facilitators of and barriers to viral load suppression among people living with HIV on ART in two regions with the lowest VLS, based on the UPHIA 2020-21 survey findings.

Uganda 2025-05-23 13:34:26 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."