Catherine Nabbumba
ID: UNCST-2024-R002912
|
Genome wide association studies and polygenic prediction of major depressive disorder in samples of African ancestry from Uganda
REFNo: HS5159ES
1) investigate the prevalence and sociodemographic and clinical correlates of MDD among general outpatients attending care at 5 hospitals in Uganda
2) undertake a systematic review on common genetic variants associated with MDD among respondents of non-European ancestry using different datasets from PGC
3) explore common genetic variants associated with MDD in 2 African samples (ED6 study (n=150 cases, 150 controls) (A) and NeuroGAP study (n=324 cases, 876 controls) (B))
4) optimise a PRS for MDD initially developed from MDD-PGC datasets for use in the African setting of Uganda
|
Uganda |
2024-11-18 13:36:01 |
2027-11-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
THOMSON LAKWO LURONI
ID: UNCST-2023-R007843
|
Evaluating the specificity and cross-reactivity of Mansonella perstans sera against biomarkers for Onchocerca volvulus and Wuchereria bancrofti
REFNo: HS4889ES
To evaluate the specificity and cross-reactivity of M. perstans sera against biomarkers of O. volvulus and W. bancrofti.
|
Uganda |
2024-11-18 13:34:32 |
2027-11-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Rogers Kalyetsi
ID: UNCST-2024-R004177
|
GENETIC DIVERSITY OF PLASMODIUM FALCIPARUM AND VECTOR SPOROZOITE INFECTIVITY RATES IN SELECTED FLOOD PRONE VILLAGES IN KASESE DISTRICT, WESTERN UGANDA
REFNo: HS4978ES
d. Generate maps for the spatial distribution of infected Anopheles mosquitoes and identify the hot spots in the flood-prone selected villages in Kasese district.,C. To determine vector species composition and sporozoite effectivity rates in selected flood-prone villages in Kasese district,b. Describe the genetic diversity of P. falciparum species responsible for malaria epidemics in selected flood-prone villages in Kasese district.,a. To establish the positivity rates of P. falciparum among children ≤ 12 years in selected flood-prone villages in Kasese district ,To determine the genetic diversity of Human Plasmodium falciparum species and vector sporozoite effectivity in selected flood-prone villages in Kasese district, western Uganda,
|
Uganda |
2024-11-18 13:24:42 |
2027-11-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Noah Nyende Robert
ID: UNCST-2024-R003575
|
Health-Seeking Behaviour and Utilization of Sexual and Reproductive Health Services by Adolescents in Uganda: An Analysis of Attitudes, Perceptions and Preferences in The Busoga Region.
REFNo: SS3374ES
4. To assess how personal factors moderate the effect of health-seeking behaviours and the utilization of SRH services by adolescents in the Busoga region of Uganda,3. To examine the relationship between health-seeking preferences and the utilization of sexual and reproductive health (SRH) services by adolescents in the Busoga region of Uganda.,2. To explore the influence of health-seeking perceptions on the utilization of sexual and reproductive health (SRH) services by adolescents in the Busoga region of Uganda.,1. To investigate the effect of health-seeking attitudes on the utilization of sexual and reproductive health (SRH) services by adolescents in the Busoga region of Uganda.,This study aims to investigate the influence of health-seeking behaviours on the utilization of sexual and reproductive health (SRH) services by adolescents in the Busoga region of Uganda. The ultimate objective is to contribute to the creation of an evidence-based model that improves the delivery and acceptance of SRH services among adolescents in Uganda.,
|
Uganda |
2024-11-18 13:22:16 |
2027-11-18 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
LADY MARY KABAPAGASA
ID: UNCST-2024-R002479
|
DIGITAL LITERACY COMPETENCIES AND SKILLS AMONG INFORMAL SMALL-SCALE WOMEN TRADERS IN THE RWENZORI REGION, UGANDA
REFNo: SS3371ES
5. To develop a policy brief to empower informal women traders with digital literacy skills and competencies in the country.,4. To examine the support systems available to informal small-scale women traders to optimally use digital devices and platforms to enhance their businesses in Rwenzori region,3. To examine the factors that influence the use of digital devices and platforms by informal small-scale women traders to boost trade in Rwenzori region,2. To establish digital literacy competencies and skills among informal small-scale women traders that enhance their use of digital devices and platforms for trade in Rwenzori region,1. To establish the types and application of digital devices and platforms that informal small-scale women traders use to enhance performance of their trade in Rwenzori region.,To examine the digital literacy competencies and skills among informal small-scale women traders in Rwenzori region, Uganda aiming to develop a national policy brief for empowering them with relevant digital literacy competencies and skills.,
|
Uganda |
2024-11-14 9:11:43 |
2027-11-14 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Deo Wabwire Ogema
ID: UNCST-2021-R013932
|
A Phase 2 Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB) Version 2.0, Dated 21 Mar 2024
REFNo: HS5088ES
Primary objectives
(i)To compare Mycobacterial Growth in Tube (MGIT) liquid culture Time to Positivity (TTP) slope over the first 6 weeks of treatment for each experimental treatment arm to the standard of care (SOC) arm.
(ii)To compare new Grade 3 or higher adverse events (AEs) (safety) over the first 8weeks of treatment for each experimental treatment arm to the SOC arm.
Secondary Objectives
i)To compare time to stable culture conversion by MGIT liquid culture by week 8
for each experimental treatment arm to the SOC arm.
ii)To compare MGIT liquid culture TTP slope over the first 8 weeks of treatment for
each experimental treatment arm to the SOC arm.
iii) To compare new Grade 3 or higher AEs (safety) over 26 weeks of treatment for
each experimental treatment arm to the SOC arm.
iv) To compare discontinuations of anti-TB drugs for any reason prior to 8 and 26
weeks of treatment for each experimental treatment arm to the SOC arm.
v) To determine the dose- and exposure-response relationships between experimental drug estimated pharmacokinetic (PK) parameters with safety and efficacy.
vi) To compare a composite of efficacy and safety outcomes using a risk-benefit
approach for each experimental treatment arm to the SOC arm.
vii) To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for Arms 3A-3B and Arms 4A-4B compared to Arm 2.
viii) To compare durable cure by 52 weeks after treatment initiation in each
experimental treatment arm to the SOC arm.
|
Uganda |
2024-11-13 18:02:04 |
2027-11-13 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
|
Heat-stable carbetocin for the treatment of postpartum haemorrhage: a phase III, randomized, double-blind, active controlled, multicountry, multicentre, non-inferiority trial
REFNo: HS5151ES
To evaluate the cost-effectiveness of the PPH treatment with HSC compared to PPH treatment with oxytocin, if HSC is proven non-inferior. ,To evaluate the comparative effects of HSC versus oxytocin on haemodynamic outcomes when used for PPH treatment in women receiving HSC for prophylaxis; ,The primary objective of this trial is to evaluate whether HSC is non-inferior to oxytocin for treatment of PPH in women who receive HSC for PPH prophylaxis, in the prevention of additional blood loss of 500 ml or more at 90 min following randomization. ,
|
Uganda |
2024-11-13 17:36:53 |
2027-11-13 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Gertrude Namazzi
ID: UNCST-2024-R002568
|
Mapping the Bottlenecks and Challenges of the At-Risk Surveillance System for Child Developmental Disabilities in Uganda
REFNo: HS5106ES
To map the bottlenecks and challenges of the At Risk Surveillance system for child developmental conditions and disabilities in order to inform targeted strategies to improve the overall effectiveness of the ARSS system,
|
Uganda |
2024-11-13 17:34:14 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
ANTHONY NUWA
ID: UNCST-2022-R011102
|
Across Sectional Survey to improve the capacity of the healthcare system to detect, report,
and respond to arboviral threats in Uganda.
REFNo: HS5063ES
1. To ascertain the availability and density of mosquito vector species involved in virus
transmission and their bionomics in Uganda.
2. To describe and document the current practices on diagnosis and management of
arboviral diseases in Uganda and provide recommendations for improvement and
strengthening.
3. To describe the current arboviruses data collection, reporting and data use system for
decision making in Uganda.
4. To evaluate current arboviral outbreak detection and response mechanisms in Uganda
To evaluate outbreak hotspots and human/animal cluster susceptibilities to identify
appropriate target sentinel sites.
6. To determine the Yellow Fever, Chikungunya, O’nyong nyong epidemic potential based
on findings from the entomological and historical data collected during the study.
7. To assess knowledge, attitudes and practice among target communities regarding
arbovirus awareness and risk behavior.
|
Uganda |
2024-11-13 17:30:13 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
|
Clinical Performance Evaluation of POC BVBLUE Test for Diagnosis of Bacterial Vaginosis in Uganda
REFNo: HS5231ES
To evaluate the performance of the BVBlue test, a point-of-care test, compared to Amsel, Nugent and Allplex Bacterial Vaginosis plus Assay. ,
|
Uganda |
2024-11-13 17:27:22 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
RUKUNDO LYDIA LYDIA
ID: UNCST-2023-R005547
|
PSYCHOSOCIAL CHALLENGES AND COPING STRATEGIES OF CARE - GIVERS OF CHILDREN WITH SICKLE CELL DISEASE AGED 0-9, ATTENDING MULAGO SICKLE CELL CLINIC
REFNo: HS4975ES
To document the coping strategies adopted by care-givers of children with sickle cell disease, attending MSCC. ,To explore the psychosocial challenges experienced by care-givers of children with sickle cell disease, attending MSCC. ,To explore the psychosocial challenges and coping strategies of care-givers of children with sickle cell disease, attending MSCC. ,
|
Uganda |
2024-11-13 17:19:00 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
|
Rapid AI-assisted Echocardiography Detection and Analysis of Rheumatic Heart Disease
(RADAR) Tool – Evaluation of Acceptability and Feasibility for Field Deployment
REFNo: HS4948ES
Specific Objective 1: To assess the acceptability of this AI tool by the team members (echo nurses) in the echo screening environment.
Specific Objective 2: To evaluate the feasibility of this tool in the echo screening setting. These measures include evaluating time from screening to results, reliability of real-time image transfer from
the echo device to the RADAR tool, and functionality of the device in this environment (i.e. battery life, heat tolerance).
|
Uganda |
2024-11-13 17:17:03 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
STELLA KIZANYE
ID: UNCST-2024-R003321
|
Design and Fabrication of a Plastic Processing Machine for Recycling High-Density Polyethylene and Polypropylene Plastic Waste- A Means of Environment Reclamation.
REFNo: SIR399ES
1. To collect data about plastic waste collected daily by Kampala waste management centres so as to inform the extent of plastic waste accumulation and show the need for collection of this problem.
2. To determine the design parameters of the components of the plastic processing/recycling machine in relation to the industry standards and need requirements.
3. To fabricate the plastic processing machine so that the recycling process can be initiated.
4. To test the machine by processing a sample of HDPE and PP plastic waste into plastic products.
|
Uganda |
2024-11-13 17:08:35 |
2027-11-13 |
Engineering and Technology |
Non-Clinical Trial |
Non-degree Award |
|
Priscilla Namaganda
ID: UNCST-2019-R001653
|
Oncogenic viral proteins associated with lymphomas at the Uganda Cancer Institute, Uganda, a comparison between HIV-associated and non-HIV-associated lymphomas.
REFNo: HS4342ES
To describe the oncogenic viral protein patterns among lymphomas at the Uganda Cancer Institute (UCI), comparing HIV-associated and non-HIV-associated lymphomas.,To determine the effect of oncogenic viral proteins on treatment outcomes of lymphoma among patients, HIV infected and uninfected at the UCI. ,
|
Uganda |
2024-11-13 17:04:50 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Rosalind Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
|
CROWDSOURCING A TRAINING DATASET OF QUESTION-AND-ANSWER PAIRS FOR ARTIFICIAL INTELLIGENCE-ENABLED HEALTH INFORMATION TOOLS ON SEXUALLY TRANSMITTED INFECTIONS
REFNo: HS5173ES
To provide to the public, an open-access, contextualized training dataset of question-and-answer pairs (Q&A pairs) on sexual health and Sexually Transmitted Infections (STIs) in English. ,To process and curate and the question-and-answer pairs into a training dataset for AI-enabled sexual health information tools.,To provide accurate, evidence-based answers, based on the World Health Organization Guidelines, to questions collected on sexual health and Sexually Transmitted Infections (STIs) from the general public in English in Sub-Saharan Africa.,To collect contextualized English questions on sexual health and Sexually Transmitted Infections (STIs) from the general public using the internet and public events in Sub-Saharan Africa over a period of six months.,The study’s main objective is to engage communities so as to develop an open-access, contextualized question-and-answer-pair training dataset on sexual health in English for AI-enabled health information tools.,
|
UK |
2024-11-13 16:57:49 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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David Onyango
ID: UNCST-2024-R004067
|
Stress Coping Mechanism and Trauma of Poverty among Adolescent in Information Settlements Tororo Municipality Tororo District Uganda
REFNo: SS2799ES
To investigate stress coping mechanisms and trauma of poverty among adolescents living in informal settlements in Tororo Municipality, Tororo District, Ugandan,
|
Uganda |
2024-11-13 16:54:19 |
2027-11-13 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Patrick Kyamanywa Edrin
ID: UNCST-2024-R004239
|
Burden, access to care and health seeking behaviour for surgical diseases among refugees in Uganda
REFNo: HS4764ES
iii. To explore the health seeking behavior among refugee populations in Nakivale refugee settlement in Uganda ,ii. To assess the drivers and barriers of access and utilization of surgical care among refugee populations in Nakivale refugee settlement in Uganda ,i. To estimate the burden (prevalence, nature, mortality) due to of surgical conditions among refugee populations in Nakivale refugee settlement in Uganda ,To describe the surgical disease burden, assess access to surgical care and explore the health seeking behavior for surgical care and the social determinants of health influencing access to surgical care among refugees in Nakivale Refugee Settlement in Uganda. ,
|
Uganda |
2024-11-13 16:50:43 |
2027-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Robert Bagumisiriza
ID: UNCST-2024-R003812
|
Evaluating the effectiveness of collaborations between TVET institutions and industry in the enhancement of employability in Uganda
REFNo: SIR447ES
To evaluate the effectiveness of collaborations between TVET institutions and industry on the enhancement of employability skills of TVET graduates.,To determine the impact of collaboration on the training opportunities for TVET trainers.,To determine the influence of collaboration in promoting sharing of training resources between industry and TVET training institutions.,To assess the impact of collaboration on enhancement of participation of industries in practical training in TVET training institutions.,To evaluate the extent of collaboration in curriculum development between TVET training institutions and industry on the enhancement of the employability skills of TVET graduates.,
|
Uganda |
2024-11-13 16:43:59 |
2027-11-13 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
|
Ezekiel Mupere
ID: UNCST-2024-R003962
|
A Randomized Clinical trial: Supplemental choline to prevent and treat learning and memory deficits of early iron deficiency. The SupCHO study
REFNo: HS4915ES
Conduct a randomized, placebo-controlled clinical trial to test whether nine months of daily choline supplementation improves hippocampus-dependent neurobehavioral outcomes in 6-month-old infants with iron deficiency anemia.,
|
Uganda |
2024-11-13 16:35:35 |
2027-11-13 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Birungi Edwin Mutahunga Rwamatware
ID: UNCST-2021-R004880
|
Bantu Social Networks and Health-Seeking Behaviours: Semi-Structured Interviews on Practices and Substantive Beliefs in the Buganda and Kigezi Communities of Uganda
REFNo: SS3337ES
The second objective of the study is to use the scientifically-gathered local information to ensure future clinical tools used in hospitals and by village health workers fit the communities studied in the regions of Buganda and Kigezi; the tool we have in mind is for stroke patients,The purpose our study is to gather first-hand accounts of practices and substantive beliefs that shape what actions people take when they face health challenges so that communities can be healthier.,The first objective is to gather local knowledge with rigor and systematic data-gathering practices so that communities can better understand themselves through their health/life-seeking behaviours and thereby better assist one another when facing health challenges.,
|
Uganda |
2024-11-13 16:32:43 |
2027-11-13 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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