Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Victoria Nankabirwa
ID: UNCST-2021-R011871
A Case Control Study to Assess Effectiveness and Safety of the R21/Matrix M Malaria Vaccine.
REFNo: HS5891ES

1) To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against
severe malaria caused by Plasmodium falciparum.

2) To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against
clinical malaria caused by Plasmodium falciparum in high-transmission
perennial areas.

3) To assess if the R21/Matrix-M vaccine recipients are at an increased risk of
death (all-cause).
Uganda 2025-04-25 9:46:49 2028-04-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Semambo Sempebwa
ID: UNCST-2021-R011977
Evaluation of Welcome Sesame: Inclusion and Belonging for Displaced Learners in Uganda
REFNo: SS3837ES

Objectives:

Main Objective
1. The main objective/ purpose of this study is to examine the effectiveness of the Welcome Sesame Program for Inclusion and Belonging for Displaced Learners in Uganda.

Specific Objectives
1. Objective 1: To Enhance the capacity of early learning settings to support inclusion and belonging for all learners in refugee and migrant-hosting communities.
2. Objective 2: To increase learners’ skills and dispositions towards equitable, inclusive, and pro-social behavior using the perspectives of caregivers/ parent educators, and other stakeholders as a reference.
3. Objective 3: To evaluate the process effectiveness from the perspective of different stakeholders, including partners, parents/ guardians and caregivers/ parent educators, about what is and is not working well under the different units of Welcome Sesame and identify what needs to be further refined prior to implementing subsequent interventions.
Uganda 2025-04-24 12:45:39 2028-04-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peterson Kikomeko Kato
ID: UNCST-2019-R000881
Ethnicity and Nutritional Status of Children Aged 0-59 Months in Kiryandongo and Kyangwali Refugee Settlement and Host Community
REFNo: HS5885ES

1.To assess the demographic characteristics of Congolese and South Sudanese refugees in Kyangwali and Kiryandongo refugee settlements and those of their host communities 2.To analyse the nutritional status of Congolese and South Sudanese refugee children 0-59 months in Kiryandongo and Kyangwali refugee settlements and those in their respective host communities 3.To analyse the infant and young child feeding practices of Congolese and South Sudanese refugee children 0-59 months in Kiryandongo and Kyangwali refugee settlements and those in their host communities 4. Investigate the influence of ethnicity on nutritional status (wasting and stunting) of Congolese and South Sudanese refugee children 0-59 months in Kiryandondo and Kyangwali refugee settlements 5.To establish the difference in the age of growth faltering between the children of Congolese and South Sudanese aged 0-12 months in Kiryandongo and Kyangwali refugee settlements 6.To establish the difference in the age of growth faltering between the children of Congolese and South Sudanese refugee children aged 0-12 months in Kiryandondo (mainly South Sudanese) and Kyangwali (mainly Congolese) refugee settlements
Uganda 2025-04-24 12:36:55 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Protazio Sande
ID: UNCST-2024-R002344
EXPLORING THE ROLE OF BOARD GOVERNANCE IN ORGANIZATIONAL PERFORMANCE IN PUBLIC AGENCIES WITHIN UGANDA’S MINISTRY OF FINANCE, PLANNING, AND ECONOMIC DEVELOPMENT
REFNo: SS3855ES

The study aims to explore the role of board governance in enhancing organizational performance in selected public agencies under the Ministry of Finance, Planning and Economic Development in Uganda. It will investigate how board structure, board processes, and board practices influences the efficiency, effectiveness, and relevance of these organizations. The Specific Objectives are: 1. To analyze how different board structures impact the overall performance of public agencies. 2. To investigate the specific practices adopted by boards and their effects on the performance of public agencies. 3. To assess how various board processes contribute to the performance of public agencies. 4. To explore stakeholders’ perceptions about the effect of Board governance on Organizational performance.
Uganda 2025-04-24 12:31:19 2028-04-24 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Seguya Ggunga
ID: UNCST-2025-R018111
Mountain Gorilla Census in the Bwindi and Sarambwe Ecosystem
REFNo: NS955ES

The Mountain Gorilla Census is a survey that has been periodically conducted to determine the
minimum number of individual habituated and non-habituated mountain gorillas in Virunga
Bwindi Landscape. The census of mountain gorillas also helps us to understand the population
dynamics, including changes in gorilla groups composition and sizes as well as solitary males. In
addition, this survey provides the opportunity to determine levels of human disturbance as well as
the status of other large mammals in the landscape. The results from the census enable us to assess
the success of all conservation efforts aimed at protecting mountain gorillas and its habitats, as
well as to ensure that they receive continue attention from the global conservation community.

Uganda 2025-04-24 12:26:12 2028-04-24 Natural Sciences Non-Clinical Trial Non-degree Award
Robert Mugabe
ID: UNCST-2024-R004064
DESIGN OF A FUZZY LOGIC FAULT DETECTION ALGORITHM AND AUTOMATIC PHASE SWITCHING IN ELECTRIC POWER TRANSMISSION
REFNo: NS954ES

1. To develop a model, using ABCD parameters, of a long transmisision line.
2. To obtain Surge impedance loading (SIL) curves for transmission line monitoring and
fault prediction.
3. To develop a fuzzy logic fault detection algorithm.
4. To simulate the developed model and the fuzzy logic algorithm using SIMULINK
Uganda 2025-04-24 12:24:25 2028-04-24 Natural Sciences Non-Clinical Trial Degree Award
BRENDA GATI MIREMBE
ID: UNCST-2021-R013390
Improving Choice and Use of Biomedical HIV Prevention for Women in Uganda: A Couples-Based Approach (CUPID)
REFNo: HS5827ES

Aim 3: To assess CUPID implementation outcomes, and barriers and strategies to address them, to inform the adoption and integration of CUPID to support women’s PrEP uptake and use.,Aim 2: Assess the effectiveness of the CUPID intervention on PrEP uptake, persistence, and use among Ugandan women, compared to PrEP choice delivered to women only.,Aim 1: To refine CUPID intervention content and implementation to support women’s PrEP choice and use in public health settings.,
Uganda 2025-04-24 12:23:21 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamela Apio Okwir
ID: UNCST-2022-R010419
Acceptability of SMART pill bottle use among children with Rheumatic Heart Disease on oral penicillin prophylaxis in Lango Subregion, Uganda.
REFNo: HS5816ES

1. To assess the acceptability of children with RHD undergoing oral penicillin prophylaxis on use of SMART pill bottles in Lango subregion, Uganda. 2. To explore the perceptions of children with RHD undergoing oral penicillin prophylaxis on the use of SMART pill bottles in Lango subregion. 3. To determine the factors associated with acceptability of SPBs among children with RHD on oral penicillin prophylaxis
Uganda 2025-04-24 12:16:45 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dathan Byonanebye Mirembe
ID: UNCST-2024-R005315
EVALUATING ANTIRETROVIRAL THERAPY TOXICITIES AND SURVEILLANCE PRACTICES IN UGANDA (ART-TOX STUDY)
REFNo: HS5752ES

1. To describe the ART adverse events experienced by people living with HIV in Uganda
2. To determine the incidence and predictors of treatment-limiting toxicity among people living with HIV.
3. To evaluate the perceptions, barriers and facilitators of ART adverse event screening, monitoring, and
reporting in Uganda.
Uganda 2025-04-24 12:12:26 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Timothy Kintu Mwanje
ID: UNCST-2021-R013684
FORMATIVE DEVELOPMENT OF AN AI-DRIVEN CHATBOT FOR PEER SUPPORT AMONG ADOLESCENTS AND YOUNG PEOPLE LIVING WITH HIV IN UGANDA
REFNo: HS5751ES

1) To explore facilitators and barriers across
multiple stakeholder levels for implementation of generative AI chatbots
into HIV peer support initiatives. 2) To generate a contextually relevant
peer support dialogue dataset to guide development of a virtual peer
support chatbot. 3) To create and refine a prototype chatbot for AYPLHIV
peer support informed by stakeholder feedback.
Uganda 2025-04-24 12:06:29 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kara  Faktor
ID: UNCST-2024-R003145
Feasibility of expansion of an operative trauma course to Mbarara Regional Referral Hospital and impact on surgical practices among residents
REFNo: HS5724ES

Aim 1: Assess the feasibility of implementing the operative trauma course at Mbarara Regional Referral Hospital, including evaluation of knowledge acquisition (Kirkpatrick level 2). Aim 2: Evaluate changes in operative management of trauma patients by second-year surgical residents (Kirkpatrick Level 3) at Mbarara Regional Referral Hospital following the operative trauma course. Aim 3: Explore the facilitators and barriers to implementation of operative techniques by the surgical residents.
USA 2025-04-24 11:19:50 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pius Nyikirize
ID: UNCST-2024-R016279
Assessing the Data and Information Management Capacity of the Uganda Nurses and Midwives Council.
REFNo: HS5690ES

To examine the relationship between system quality, information quality, and service quality and their impact on perceived usefulness and perceived ease of use of the Uganda Nurses and Midwives Council’s data management system.

To identify the strengths and weaknesses in the data management system and processes at the Uganda Nurses and Midwives Council and make recommendations for improvement.

Uganda 2025-04-24 10:46:02 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Namaganda Rehema Rehema
ID: UNCST-2024-R005390
Understanding Older Persons' experiences with the Senior Citizen Grant (SCG) and Its implications on Care and Social Protection in Uganda
REFNo: SS3579ES

1. To analyse how the utilisation of the senior citizen grant (SCG) influences the overall care for the elderly, including their access to healthcare services.
2. Assess the impact of senior citizen grant on existing care relationships and dynamics between the state, family, community and older persons benefiting from the grant.
3. To explore how experiences of older persons receiving the senior citizen grant can inform and shape social protection policies in Uganda

Uganda 2025-04-24 10:33:06 2028-04-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vicent Mabirizi
ID: UNCST-2023-R006965
A Convolutional Neural Network Model for Processing DICOM Files
REFNo: SIR495ES

To test and validate the accuracy of the developed model for processing DICOM files for image classification.,To develop a convolutional neural network model for processing DICOM files for image classification,To explore how deep learning techniques have been applied to process DICOM files for image classification,To improve the detection and classification of DICOM images,
Uganda 2025-04-24 10:22:37 2028-04-24 Engineering and Technology Non-Clinical Trial Degree Award
Eve  Namisango
ID: UNCST-2021-R014038
A RANDOMISED CONTROLLED TRIAL TO EVALUATE THE EFFECTIVENESS OF A NURSE-LED PALLIATIVE CARE INTERVENTION FOR PEOPLE WITH HEART FAILURE IN UGANDA IN TERMS OF PATIET-REPORTED OUTCOMES
REFNo: SS3641ES

To determine patients and healthcare professional views regarding the processes, mechanisms and outcomes of the intervention.,To test the effectiveness of the nurse-led palliative care intervention among heart failure patients compared to existing care in an RCT design in terms of patient-reported outcomes.,To use findings from scoping review to generate a nurse-led palliative care intervention underpinned by the theory of person-centredness care. ,To evaluate the effectiveness of a nurse-led palliative care intervention for adult heart failure patients in Uganda on patient-reported outcomes, compared to usual care. ,
Uganda 2025-04-24 10:20:58 2028-04-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Neil Scolding
ID: UNCST-2021-R012864
Acute Flaccid Myelitis in Uganda
REFNo: HS5294ES

1. To conduct a nationwide pilot study of Acute Flaccid Myelitis to gain insights into its frequency, clinical and radiological features and virological background in a Uganda setting.
2. To develop a nationwide clinical research network allowing collaborative medical research across Uganda and boosting research activity.

UK 2025-04-11 17:38:16 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Bisegerwa
ID: UNCST-2022-R011022
Global characterization of skin color to improve the accuracy of pulse oximeters.
REFNo: HS4069ES

To determine the optimal method of skin color determination,To determine the range of skin color among the heterogeneous population in Uganda. ,To characterize the wide range of skin colors that exist globally by taking a sample of skin color measurements from people in a diverse country such as Uganda,
Uganda 2025-04-11 17:37:01 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Andima
ID: UNCST-2023-R008107
Laboratory scale production of beta propiolactone (BPL) from cassava for application in the pharmaceutical industrial value chains
REFNo: NS827ES

The main objective of the project is to assess the chemical conversion of ethanol from cassava to produce a more valuable product, beta propiolactone (BPL) and determine if this conversion is viable on an industrial scale

4. VENTURE OBJECTIVES
Specifically, we aim at;
1. Optimizing production process for beta propiolactone
2. Synthesizing the intermediate chemicals (ethanol, ethylene and ethylene oxide) required for BPL production
3. Producing beta propiolactone at laboratory scale for inactivation of viruses during vaccine development.
4. Establishing the quality profile of the synthesized BPL
Uganda 2025-04-11 17:34:53 2028-04-11 Natural Sciences Non-Clinical Trial Non-degree Award
Birungi Edwin Mutahunga Rwamatware
ID: UNCST-2021-R004880
Bwindi mHealth: Improving data capture at the point of zoonotic disease spillover.
REFNo: HS5805ES

To expand surveillance in the region, incorporating an integrated mHealth One Health approach for early recognition of zoonotic spillover, Create an integrated One Health AFI outbreak alert system; a dashboard identifying clusters of human AFI cases and wildlife events surrounding the Bwindi Impenetrable Forest,To expand surveillance in the region, incorporating an integrated mHealth One Health approach for early recognition of spillover.,Develop passive geolocation system, which will improve accuracy of geolocation data of reports of potential outbreaks. ,Optimize a mobile phone APP capable of assisting health professionals and VHT members in triage, diagnosis, and treatment of common zoonotic diseases.,Develop a Village Health Team (VHT) network data collection system for acute febrile illness (AFI), which builds upon the existing mobile community health information system (mCHIS), run and responded to by healthcare workers at Bwindi Community Hospital. ,
Uganda 2025-04-11 17:32:29 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Loy Muhwezi Abaine
ID: UNCST-2024-R003586
ASSESSING THE IMPACT OF QUALITY ASSURANCE PRACTICES ON THE QUALITY OF PUBLIC TECHNICAL AND VOCATIONAL EDUCATION AND TRAINING COLLEGES IN UGANDA
REFNo: SIR479ES

To determine the industry employer involvement in QA practices in public TVET colleges in Uganda,To determine strategies used by trainers to improve their QA practices in public TVET colleges in Uganda,To establish the trainees’ perspective on QA practices in public TVET colleges in Uganda.,To explore the role of management in QA practices in public TVET colleges in Uganda.,The main objective of this study is to assess the existing QA practices in public TVET colleges in Uganda.,
Uganda 2025-04-11 17:31:19 2028-04-11 Engineering and Technology Non-Clinical Trial Degree Award
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