Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Tom Okade
ID: UNCST-2024-R004140
Water, Sanitation and Hygiene (WASH) factors and their association with nutritional status of under-five children: A case study of Informal settlements (Slums) in Kampala, Uganda
REFNo: HS7697ES

1. To establish the household Water, Sanitation and Hygiene practices in informal settlements in Kampala, Uganda 2. To determine the prevalence of stunting, underweight and wasting among under-five children in informal settlements in Kampala, Uganda 3. To determine the association between household Water, Sanitation and Hygiene practices and nutritional status (Stunting, Underweight and Wasting) of under-five children in informal settlements in Kampala, Uganda
Uganda 2026-06-11 13:11:06 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PATRICK KAKANDE
ID: UNCST-2025-R020509
HUMAN PAPILLOMA VIRUS VACCINATION: UPTAKE, ASSOCIATED FACTORS, BARRIERS AND FACILITATORS AMONG FEMALE ADOLESCENTS LIVING WITH HIV AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS7400ES

To determine the uptake of HPV vaccination, associated factors, barriers and facilitators among female adolescents living with HIV at Mbarara regional referral hospital.
Uganda 2026-06-11 12:58:14 2029-06-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Leonie Gussone
ID: UNCST-2026-R024667
Mapping the invisible: Primate movement ecology as a window into internal states and external pressures
REFNo: NS1284ES

To test how variation in movement patterns of red-tailed monkeys reflect internal states (measured through a panel of non-invasive biomarkers) and external pressures (food availability and competition)
Germany 2026-06-11 12:50:42 2029-06-11 Natural Sciences Non-Clinical Trial Degree Award
Daisy Kamusiime
ID: UNCST-2025-R020451
Sign Language Enabled Technology (SLET4TB) for Accessible TB Care in Uganda
REFNo: HS7856ES

i. To assess changes in healthcare providers’ confidence in communicating with Deaf TB patients before and after SLET implementation. ii. To evaluate the impact of SLET on consultation efficiency (duration and activities) for Deaf TB patients in the selected districts of Kampala, Wakiso and Mukono. iii. To determine the usability of SLET among healthcare providers using the System Usability Scale (SUS). iv. To explore acceptability, barriers, and facilitators among Deaf users, providers and stakeholders.
Uganda 2026-06-11 12:43:33 2029-06-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Joseph Ochom
ID: UNCST-2025-R022492
REVENUE DIVERSIFICATION, FINANCIAL PLANNING AND FINANCIAL SUSTAINABILITY OF PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS5076ES

The study will be guided by the following objectives. I. To examine the extent to which grants and donations contribute to revenue diversification and financial sustainability of Uganda’s public universities. II. To assess how tuition and functional fees, as components of revenue diversification, influence the financial sustainability of Uganda’s public universities. III. To analyze the role of research and consultancy services in enhancing revenue diversification and financial sustainability of Uganda’s public universities. IV. To evaluate the contribution of commercial activities and enterprise ventures to revenue diversification and financial sustainability of Uganda’s public universities. V. To examine the mediating role of financial planning in the relationship between revenue diversification and financial sustainability of Uganda’s public universities
Uganda 2026-06-11 12:41:36 2029-06-11 Social Science and Humanities Non-Clinical Trial Degree Award
Racheal Angom
ID: UNCST-2023-R007485
Enhancing Pediatric Cancer Care in Uganda with the Uganda Cancer Institute Pediatric Cancer Registry and the Uganda Cancer Institute Pediatric Cancer Dashboard
REFNo: HS7853ES

To Assess the feasibility, acceptability, and preliminary impact of UCI-Ped-Reg and UCI-Ped-DASH.,To assess the barriers and facilitators to implementation and adoption of UCI-Ped-Reg and UCI-Ped-DASH.,To develop and implement an online interactive dashboard (UCI-Ped-DASH) for real-time data visualization from UCI-Ped-Reg.,To implement an adapted hospital-based pediatric cancer registry (UCI-Ped-Reg) at the Uganda Cancer Institute, Kampala, Uganda.,To enhance pediatric cancer care in Uganda by developing and implementing a hospital-based pediatric cancer registry (UCI-Ped-Reg) and an interactive data visualization dashboard (UCI-Ped-DASH) at the Uganda Cancer Institute (UCI).,
Uganda 2026-06-11 12:37:21 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
Understanding and Strengthening Systems of Evidence to Improve Health Policy in Africa: A Comparative Multi-Country Study
REFNo: HS7883ES

4) Development and monitoring of action plans for national stakeholders working to improve evidence systems for health,3) Comparative analysis of the operation of these systems in relation to two contrasting health policy challenges (Universal Health Care and COVID-19),2) Conceptual development of a framework on which to evaluate the structure and function of these systems, co-produced with key stakeholders,1) Mapping national evidence advisory systems, institutional arrangements, and cultures of evidence at national and local government levels,to examine and inform evidence advisory systems that inform health policymaking through a comparative analysis of how these systems function and can be improved in four African countries - Kenya, Malawi, Rwanda, and Uganda,
Uganda 2026-06-11 12:34:51 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AbdulAziizi Sekitooleko
ID: UNCST-2025-R019865
E-Governance and Tax Administration in Local Governments in Uganda: A Study of Bushenyi District
REFNo: SS5201ES

1.3.1 Purpose of the study To examine the effects of e-governance on tax administration in Bushenyi District local government Uganda. Specific objective i. To establish the effects of online tax registration on tax administration in Bushenyi district local government ii. To examine the effects of Automated revenue collection systems on tax administration in Bushenyi district local government iii. To identify the effects of Integrated Financial Management Information system (IFMS) on tax administration in Bushenyi district local government. iv. To assess the moderating effect of Government Policy on the relationship between; online tax registration, Automated revenue collection systems, Integrated Financial Management Information system (IFMS), and tax administration in Bushenyi District Local Government.
Uganda 2026-06-11 12:29:30 2029-06-11 Social Science and Humanities Non-Clinical Trial Degree Award
Lydia Nakiyingi
ID: UNCST-2022-R010102
Metformin as the Silver Lining for Diabetics Co-infected with Drug Sensitive Tuberculosis: Understanding the Clinical Aspects of Metformin’s Modification of Tuberculosis
REFNo: HS7668ES

To assess the anti-tuberculous activity of metformin among diabetes
mellitus patients with tuberculosis Kiruddu Hospital and Kisenyi HC IV , through comparing
clinical presentation, rate of symptom resolution, rate of smear conversion and frequency of
successful outcomes among drug susceptible tuberculosis patients receiving metformin for
diabetes mellitus when compared to those not on metformin.
Specific objectives:
1. To describe the clinical and radiological presentation of tuberculosis disease among
drug susceptible tuberculosis patients receiving metformin for diabetes mellitus
treatment and those not receiving metformin at Kiruddu Hospital and Kisenyi HC IV.
2. To evaluate clinical progression (resolution of symptoms and conversion to sputum
smear negativity) among drug susceptible tuberculosis patients receiving metformin
for diabetes mellitus treatment and those not receiving metformin at Kiruddu Hospital
and Kisenyi HC IV.
3. To compare successful tuberculosis treatment outcomes among drug susceptible
tuberculosis patients receiving metformin for diabetes mellitus treatment and those
not receiving metformin at Kiruddu Hospital and Kisenyi HC IV.
Uganda 2026-06-11 12:13:55 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Japheth Noel
ID: UNCST-2021-R013959
Refugee Students in Uganda’s Higher Education System: A Grounded Theory Study on Conditions for Successful Integration
REFNo: SS5259ES

The main objective of the study is to develop a theoretical model for successful integration of refugee students in the Ugandan higher education system that is based on the attributes, perspectives, experiences and strategies(enablers) and constraints(disablers) for their access, participation and success in Ugandan higher education system.
Uganda 2026-06-11 12:12:13 2029-06-11 Social Science and Humanities Non-Clinical Trial Degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
Formative Usability Study Protocol of the Panbio™ Dengue Duo test with Fingerstick Sample Collection
REFNo: HS7731ES

The primary objectives of this usability study are
• To evaluate Health Care Professional users’ Panbio™ Dengue Duo test labelling comprehension and the usability of the supplied components as describe in the IFU in a Point of Care setting. This will be assessed through the user questionnaire and observation sheets.
• To assess which lancet generates the correct volume of blood to enable to user to collect two samples from the same fingerstick.
• To identify the optimal instruction and technique for using the plastic capillary tube to collect the 30 µL from a fingerstick and to understand the impact of fingerstick on the usability of the sample collection tools.

Uganda 2026-06-11 12:06:13 2029-06-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
Learning together to advance Evidence and Equity in Policymaking to achieve the SDGs in Africa (Africa LEEPS)
REFNo: SS5344ES

The overall objective is to strengthen evidence pathways at regional and national levels to ensure timely access to relevant, contextualized evidence, including gender analysis, for policymaking that enhances population wellbeing.,4. To build a culture of sustained evaluation, knowledge exchange, and learning within the LEEPS partnership and the partners within the EARESI. ,3. To design a platform structures and processes to support timely access and use of evidence response at regional level for gender equity and inclusion in policymaking to enhance population wellbeing.,2. To strengthen the sustained capacity of individuals and organisations in applying evidence and gender equity and inclusion in policymaking to enhance population wellbeing,1. To strengthen evidence pathways at a regional policymaking to strengthen timely access to relevant and contextualised evidence, including gender analysis, for informing decisions to enhance population wellbeing,
Uganda 2026-06-11 12:04:48 2029-06-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
Platform Adaptive Randomised Trial for NEw and Repurposed Filovirus treatmentS
REFNo: HS7849ES

To evaluate the impact of potential treatments on mortality in patients with filovirus disease. ,
Uganda 2026-06-08 21:31:41 2029-06-08 Medical and Health Sciences Clinical Trial Non-degree Award
Derrick Abila Bary
ID: UNCST-2020-R014563
Feasibility, acceptability, and preliminary outcomes of childhood cancer survivor-delivered nurse-facilitated peer support model on anxiety and depression among adolescents newly diagnosed with cancer at Uganda Cancer Institute (UCI), Uganda
REFNo: HS7533ES

1) To co-design with stakeholders the TOGETHER implementation strategies for adolescents newly diagnosed with cancer at UCI, Uganda,To evaluate the feasibility, acceptability, appropriateness, and preliminary outcomes of TOGETHER (a peer-support intervention delivered by childhood cancer survivors and nurse facilitators) on anxiety and depression among adolescents newly diagnosed with cancer at the Uganda Cancer Institute (UCI). 2) To pilot test the TOGETHER implementation strategies among adolescents newly diagnosed with cancer at UCI, Uganda, using a hybrid type II effectiveness implementation trial design. 3) To assess the perceived barriers and facilitators of a childhood cancer survivor (CCS) delivered nurse-facilitated peer support model (TOGETHER) for adolescents newly diagnosed with cancer at UCI, Uganda.
Uganda 2026-06-08 16:16:30 2029-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Derrick Abila Bary
ID: UNCST-2020-R014563
COMPARATIVE STUDY OF THE CERVICAL CANCER SCREENING FOR PREVENTION AND CONTROL PROGRAM: A CASE OF MBARARA MBARARA/CITY VS GULU DISTRICT/CITY
REFNo: HS7800ES

Main Objective
1. To evaluate the effectiveness of cervical cancer screening interventions at intervention sites compared with control sites in Gulu City and Gulu District during the same period.

Specific Objectives
1. To determine the number and proportion of precancerous lesions detected among women screened for cervical cancer in the intervention sites and compare these with the control sites.
2. To compare screen-positive treatment rates in the intervention and control sites before and after the intervention.
3. To assess the investments (costs) made to facilitate cervical cancer screening in the intervention sites compared with the control sites.
4. To compare the level of cervical cancer knowledge, awareness, and practices between the women in the communities in the intervention and control sites.
5. To explore stakeholder perspectives on the implementation, acceptability, barriers, facilitators, and sustainability of cervical cancer screening service delivery in the intervention and control sites.
Uganda 2026-06-08 16:04:57 2029-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
Piloting the use of sub-Saharan Africa spirituality guidelines and standards to support the integration of spirituality care into routine palliative care services at Kitovu Mobile hospice
REFNo: SS5371ES

2) To build a core team of palliative care and community health workers trained in generalist spiritual care ,1) To co-design a strategy for integrating spiritual care into routine palliative care services at Kitovu Mobile,To undertake a demonstration project on how to integrate spiritual care into routine palliative care leveraging evidence-based recommendations and standards alongside appropriate measures for assessment, management/support and measuring outcomes,
Uganda 2026-06-05 16:41:18 2029-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
Development of Host Biomarker-Guided Approaches to Mitigate Endemic and Emerging Biothreats
REFNo: HS7512ES

To conduct comprehensive host transcriptomic and proteomic profiling of biospecimens previously collected under IRB approved protocols meeting clinical definitions of the syndromes Pneumonia, Acute Respiratory Distress Syndrome, Sepsis and Meningoencephalitis
Uganda 2026-06-05 16:30:22 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Katumba
ID:
Local Validation and Calibration Assessment of the CerviCARE Artificial Intelligence Cervicography Tool Within Routine VIA-Based Cervical Cancer Screening in Uganda: A Mixed-Methods Study with Comparative Patient and Provider Experience Assessment
REFNo: HS7752ES

Primary objective: To compare the diagnostic performance of the CerviCARE AI tool with VIA performed by experienced screening midwives and healthcare workers within routine cervical cancer screening services at the Uganda Cancer Institute and its affiliated satellite site in Mbarara, and to characterise the tool’s agreement, calibration and operational performance within routine service delivery. Secondary objectives 1. To assess the quality-assurance performance of CerviCARE using colposcopy-directed biopsy and histopathological confirmation among a targeted subset of approximately 180 participants with abnormal, suspicious, borderline or discordant screening findings within the 1,500-woman validation cohort. 2. To assess and compare patient and healthcare provider experiences of routine VIA-based cervical cancer screening delivered with and without CerviCARE support, including understanding of results, communication, acceptability, trust, dignity, workflow, provider confidence and perceived usefulness within routine service delivery. 3. To quantify inter-observer variability in VIA interpretation among study providers and to assess how CerviCARE outputs align with consensus VIA and histology in discordant cases.
Uganda 2026-06-05 16:26:45 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
Efficacy of a High-Calorie High-Protein Supplement on Weight for Age and Mid Upper Arm Circumference of Children with Special Needs in Uganda
REFNo: HS7734ES

Assess caregiver knowledge, attitudes and practices regarding the preparation, use and perceived benefits of the supplement,Assess the effect of the supplement on weight for age and mid upper arm circumference among children with CP,To analyze the nutrient composition of the 1-week pureed food menu provided at the orphanage using the MyDietAnalysis program to determine its adequacy in meeting the nutritional requirements of the children.,Develop an energy-protein dense supplement to improve nutritional status of children with Celebral Palsy and other disabilities.,To test the efficacy of a sustainable high-calorie, high-protein supplement in therapeutic care of malnourished Ugandan children with disabilities. ,
Uganda 2026-06-05 16:24:12 2029-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Max Bobholz
ID: UNCST-2025-R021763
Health-related quality of life and environmental distress among climate-displaced communities in Uganda
REFNo: HS7560ES

4.1. General Objective
The general objective of this study is to characterize, summarize, and explore the connection between CRD and the current health-related QoL and environmental distress circumstances of CRMs in Uganda, focusing on both the national level and within a single IDP camp.


4.2. Specific Objectives
We propose two specific objectives that run in parallel to one another.
Objective 1: Characterize key stakeholders’ understanding of the causes and health-related consequences of CRD in Uganda. This objective will investigate stakeholders’ understanding of CRM circumstances in Uganda, particularly the types of climate factors contributing to displacement, the challenges faced by this population, and potential strategies for improving their health, using key informant interviews.
Objective 2: Explore how climate-related displacement experiences, aspects of vulnerability, and resilience contribute to quality of life and environmental distress (e.g., solastalgia and loss of place) throughout migration journeys of climate-related migrants in the Muhokya IDP Camp in Kasese District. Guided by an emerging method that blends geospatial mapping and narrative analysis,20 we will qualitatively explore the displacement, QoL, and distress experiences of CRMs.

USA 2026-06-05 16:22:02 2029-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
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