Innocent Besigye Kabahena
ID: UNCST-2019-R001025
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Identifying gaps in screening, diagnosis, clinical practice guidelines and improving hypertension management in primary care facilities in Tororo District
REFNo: HS176ES
1. To identify the gaps in the health facility minimum requirements for successful screening, diagnosis and management of hypertension in Tororo district primary care facilities.
2. To establish the gap between hypertension management guidelines and clinical practice in Tororo district primary care facilities
3. To describe what needs to change for improved care of hypertension in primary care facilities in Tororo District.
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Uganda |
2018-03-14 |
2021-03-14 |
Medical and Health Sciences |
|
Non-degree Award |
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Julie Nabweteme
ID:
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A Post Mortem review of hospital-based suspected Hepatocellular cancer deaths in Uganda to examine the relationship with Schistosomiasis
REFNo: HS116ES
Primary:
• To investigate the prevalence of schistosomiasis based on histopathology findings among suspected hepatocellular carcinoma cases.
Secondary:
• To validate the diagnosis of hepatocellular carcinoma (HCC) among cases of the larger study, which is defined by clinician’s suspicion of HCC and/or presence of liver masses on ultra sound scan with liver mass histopathology obtained at the time of autopsy.
• To pathologically correlate the level of liver fibrosis due to schistosomiasis among the HCC deaths adjusting for geographical location and HIV co-infection.
|
Uganda |
2018-03-12 |
2021-03-12 |
Medical and Health Sciences |
|
Non-degree Award |
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Chienwen Kao Jennifer
ID:
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Mapping Social Networks of Child Caregiving in Uganda: A Formative Mixed Methods Study
REFNo: SS137ES
1. Use qualitative interviews to better understand the caregiving networks of female Ugandan child caregivers
2. Pilot and receive feedback on a novel social network measure designed to measure caregiving networks quantitatively
3. A preliminary exploration of how the captured social network relates to the caregiver’s depression
|
Taiwan |
2018-03-12 |
2021-03-12 |
Social Science and Humanities |
|
Degree Award |
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Charles Namisi Patrick
ID: UNCST-2019-R001073
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DEVELOPMENT OF A MEASURE TO EMPOWER ADULT PEOPLE WITH HIV IN STIGMA MANAGEMENT, UGANDA
REFNo: SS146ES
This study is conceptualised within empowerment framework, with the purpose to develop and evaluate a measure for empowering adult people in stigma management in Uganda.
Specifically, the study will address the three related objectives below;
Objective 1, to determine the prevalence and associated factors for Internalized HIV-related stigma among adult PLHIV (Sub study 1).
Objective 2, to develop a measure for empowering people living with HIV in stigma management among adults with HIV (sub study 2).
Objective 3 a) to evaluate psychometric properties of the Empowerment Questionnaire for HIV-related Stigma Management (EQ-HSM) (Sub study 3).
|
Uganda |
2018-03-09 |
2021-03-09 |
Social Science and Humanities |
|
Degree Award |
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Philipp Trotter
ID:
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Optimal energy planning in Uganda
REFNo: SIR7ES
There are three major aims of the study:
1. Understand the electricity consumption patterns and current energy situation for Ugandan households in different regions in Uganda
2. Understand the requirements and desires of Ugandan households with regards to Uganda’s energy future
3. Construct an optimization model of the Ugandan electricity infrastructure which analyses different energy future pathways
|
UK |
2018-03-06 |
2021-03-06 |
Engineering and Technology |
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Degree Award |
|
Patricia NAHIRYA Ntege Nahirya
ID: UNCST-2019-R001117
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HPTN 084 - A Phase 3 Double Blind Safety and Efficacy Study of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women
REFNo: HS147ES
Primary Objectives
• Efficacy: To evaluate the relative efficacy of oral CAB/CAB LA (oral run-in and injections, Steps 1 and 2) vs. daily oral TDF/FTC for HIV prevention (Steps 1 and 2).
• Safety: To evaluate the relative safety of oral CAB/CAB LA (oral run-in and injections, Steps 1 and 2) vs. daily oral TDF/FTC for HIV prevention (Steps 1 and 2).
Secondary Objectives
• To compare HIV incidence among participants receiving oral CAB/CAB LA vs. daily oral TDF/FTC (Steps 1, 2 and 3).
• To evaluate relative efficacy of oral CAB/CAB LA vs. oral TDF/FTC in subgroups defined by the baseline factors of: age, herpes simplex virus-2 (HSV-2) serostatus, contraceptive method, and body mass index (BMI).
• To describe and model the relationship between HIV incidence and drug concentration, within each arm.
• To describe the distribution and correlates of drug concentration, within each arm.
• To compare the acceptability of and preferences for CAB LA vs. oral TDF/FTC.
Tertiary Objectives
• To estimate and compare sexual risk behaviors, as measured by self-report and rates of incident sexually transmitted infections (STIs), between study arms.
• To compare Grade >2 AE rates in women with baseline BMI
|
Uganda |
2018-03-06 |
2021-03-06 |
Medical and Health Sciences |
|
Non-degree Award |
|
Simon Sensalire
ID:
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Assessment of Effectiveness and Cost-effectiveness of the Quality Improvement Guide on Maternal and Newborn Care in Uganda
REFNo: HS162ES
1 Evaluate the change in QI-related actions (defined as; establishing improvement team, identifying gaps in quality of care and particular barriers causing the gap, deciding what to improve, plan, test and implement interventions to address identified gap, routinely monitor the progress of improvement and institutionalize improvement and successful changes in the facility) and knowledge among health care providers and managers from targeted health facilities using different implementation strategies vs business as usual (control group).
2 Determine the change in quality of maternal and newborn care processes (defined as every patient receiving the recommended services every time it is appropriate) and outcomes from pre-intervention to post-intervention in health facilities which have been exposed to the three different implementation strategies.
3 Determine the incremental cost-effectiveness ratio of the different implementation strategies in terms of expenditure per unit of patient care improvement achieved by the implementation strategy to each other and the control group with no incremental costs related to particular control group strategy.
4 Explore key informants perceptions of and experiences with the different intervention strategies.
|
Uganda |
2018-03-06 |
2021-03-06 |
Medical and Health Sciences |
|
Non-degree Award |
|
Susan Whyte Reynolds
ID:
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Aging as a Human Condition: Radical Uncertainty and the Search for the Good (Old) Life
REFNo: SS150ES
Through a comparative ethnographic research design, we explore the universal and the culturally specific in experiences of aging, with an eye to how local cultural resources and social structures can both afford and constrain people’s search for the good life in later years.
The specific objectives are to explore experiences of four main themes: the mindful body, intimate others, time lived, and home space
|
USA |
2018-03-06 |
2021-03-06 |
Social Science and Humanities |
|
Non-degree Award |
|
Aya Tsubota
ID:
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Work empowerment of Health Care Workers in the Republic of Uganda
REFNo: HS172ES
This research aims to identify effective factors of work empowerment for health care workers in the Republic of Uganda using the Focus Group Interview method.
|
Japan |
2018-03-06 |
2021-03-06 |
Medical and Health Sciences |
|
Degree Award |
|
KYALIMPA Paul
ID:
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LEADERSHIP COMPETENCIES AND SUSTAINABLE FUNDING OF NON-GOVERNMENTAL ORGANISATIONS IN UGANDA
REFNo: SS156ES
1.To determine the competences of Nocal NGO (LNGO) leaders in Uganda;
2.To establish the level of LNGO financial sustainability in Uganda; and
3.To establish the influence of competences of LNGO leaders on sustainable funding of LNGOs in Uganda.
|
Uganda |
2018-03-06 |
2021-03-06 |
Social Science and Humanities |
|
Degree Award |
|
John Sentongo Luyimbazi
ID:
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Increasing Efficiency and Improving Quality of Secondary Education in Sub Saharan Africa: A Case Study of Uganda
REFNo: SS163ES
Review and document evidence, background literature and policies on school efficiency in
the secondary education context,
2. Develop a theoretical framework to structure evidence and approaches to improving school
level efficiency,
3. Assess how secondary schools are governed, managed, resourced, monitored and how
resources are allocated and utilized against a benchmark or a framework,
4. Identify opportunities to increase the efficiency and effectiveness of secondary schools
through implementation of local solutions and actionable interventions, and
5. Recommend contextually relevant and innovative school efficiency measures to empower
schools to sustainably finance, effectively govern, and improve the quality of secondary
education.
|
Uganda |
2018-03-06 |
2021-03-06 |
Social Science and Humanities |
|
Non-degree Award |
|
Vitaliano Cama
ID:
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Evaluation of the Diagnostic Tests in Areas Hypoendemic for Onchocerciasis –Uganda
REFNo: HS90ES
) Evaluate the distribution of anti-OV-16 antibody and other markers of O. volvulus infection in multiple age groups.
Data from this study may allow to determine the force of infection (rate at which susceptible individuals acquire an infection) using catalytic models
|
USA |
2018-02-21 |
2021-02-21 |
Medical and Health Sciences |
|
Non-degree Award |
|
Payal Chakraborty
ID:
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Characterizing Treatment/Management and Patient Outcomes of Epilepsy in Uganda: A Prospective Cohort Study
REFNo: HS99ES
1. Characterize management of epilepsy in Mulago National Referral Hospital (MNRH), Butabika National Mental Hospital (BNMH), and Mbarara Regional Referral Hospital (MRRH).
1a. To assess treatment options available for epilepsy patients by site (MNRH, BNMH, and MRRH).
1b. To assess knowledge, attitudes, and other factors associated with treatment barriers.
2. Characterize treatment outcomes in hospital-based epilepsy care, specifically at MNRH, BNMH, and MRRH.
2a. To determine etiological risk factors and common seizure patterns associated with epilepsy that present in patients at study sites.
2b. To determine the seizure severity, quality of life, and seizure outcomes among patients with epilepsy.
2c. To determine the adherence levels and factors associated with non-adherence of anti-epileptic drugs.
|
USA |
2018-02-21 |
2021-02-21 |
Medical and Health Sciences |
|
Degree Award |
|
Alicia Rich Michelle
ID:
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Chimpanzee Highways: Gene Flow and Connectivity at Itwara Forest Reserve
REFNo: NS36ES
This study will focus on a chimpanzee metapopulation, which likely spans several protected areas in western Uganda by utilizing Itwara Forest Reserve (hereafter ‘Itwara’) as a connective corridor. Contrasting environments characterize at least two of those areas; closed-forest habitat dominates Itwara Forest Reserve (Howard 1991), while closely neighboring Toro-Semliki is usually described as an “open habitat,†(Hunt and McGrew 2002). Initial observations suggest that chimpanzees utilize a connective corridor of ~4 km between those two reserves, not only for rare dispersal events, but also for regular ranging within a single community’s territory (Rich et al. in prep). Here we are proposing to test whether chimpanzees do use a connective corridor between the two reserves, where the chimpanzee-selected corridor is, and what motivates travel through it (i.e. dispersal, foraging, etc.). We will examine the evolutionary and conservation-based implications of corridor-use by Toro-Semliki/Itwara chimpanzees and lay the groundwork for long term, multi-species connectivity research in and around Itwara Forest Reserve using indirect methods. If chimpanzees are using this corridor, then we will expand our research to examine other potential connective corridors that extend from Itwara Forest Reserve into other protected areas such as Kibale National Park and Muhangi Forest Reserve.
|
USA |
2018-02-21 |
2021-02-21 |
Natural Sciences |
|
Non-degree Award |
|
Mohammed Lamorde
ID: UNCST-2019-R001293
|
Pharmacokinetic and pharmacodynamic evaluation of etonogestrel dose escalation with efavirenz-based antiretroviral therapy in HIV-infected Ugandan women (DoublET)
REFNo: HS163ES
Primary objective:
To compare the rate of ovulation (by weekly endogenous progesterone at months 3, 6, and 12) when women receive two 68 mg ENG implants (dose-escalated) compared to one 68 mg ENG implant (standard dose) in combination with EFV-based ART.
Secondary objectives:
1. To determine cervical mucus quality (by collecting weekly WHO cervical mucus scores at months 3, 6, and 12) when women receive two 68 mg ENG implants (dose-escalated) compared to one 68 mg ENG implant (standard dose) in combination with EFV-based ART.
2. To compare the PK parameters of two ENG implants (136 mg total) with combined EFV use versus the standard dose 68 mg ENG implant with no ART (historical controls in the same population using the same laboratory1) over 6 months of combined use.
3. To evaluate the safety and tolerability of two ENG implants with combined EFV-based ART use.
4. To describe the relationship between ENG concentrations and participant specific variables, specifically body weight, albumin, sex hormone binding globulin, pharmacogenetic polymorphisms, and ART concentrations.
5. To describe the long term feasibility and tolerability of increased dose ENG (136mg) subdermal implant use in HIV-infected women receiving EFV-based ART after weeks 96 and 144 of combined use.
|
Nigeria |
2018-02-21 |
2021-02-21 |
Medical and Health Sciences |
|
Non-degree Award |
|
Emmanuel Isingoma
ID: UNCST-2019-R001057
|
Prevalence of Brucella antibodies in livestock in Karamoja, northeastern Uganda
REFNo: A28ES
1. To determine by district the prevalence of Brucella antibodies in cattle, goats and sheep in Karamoja sub-region
2. To determine the distribution of Brucella antibodies by sex of the different species of livestock
3. To determine the distribution of Brucella antibodies by age of the different species of livestock
|
Uganda |
2018-02-21 |
2021-02-21 |
Agricultural Sciences |
|
Degree Award |
|
Karolina Werner
ID:
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From Statebuilding to Localized Governance: Exploring African governance structures
REFNo: SS56ES
The project focuses on understanding the legal integration of informal/traditional authorities into the governance of states in sub-Saharan Africa. The objective is to better understand the unique systems of governance present on the continent, providing a comparative study of four countries (Uganda, Zambia, Mozambique, Botswana) with varying degrees of integration.
|
Canada |
2018-02-13 |
2021-02-13 |
Social Science and Humanities |
|
Degree Award |
|
Godfrey Zari Rukundo Zari
ID: UNCST-2019-R001500
|
Implementation and Adaptation of a Web-Based Clinical Education Program for Mental Health Providers in Uganda
REFNo: HS59ES
The objective of the study is to assess the acceptability and utility a of western-developed online CBT course in advancing knowledge of cognitive-behavioral interventions among staff and graduate students in the department of psychiatry at Mbarara University/Mbarara Hospital in southwestern Uganda. Because this is the first time the course is being offered in this manner in Uganda, it is necessary to first pilot and adapt the training modules to our local setting.
|
Uganda |
2018-02-13 |
2021-02-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Anna Stadelman Michelle
ID:
|
Assessing Lung Function and Quality of Life in Ugandans after Completion of Multi-Drug Resistant Tuberculosis Treatment (ALFU-MDR TB)
REFNo: HS122ES
To evaluate the impact of MDR TB and its treatment on pulmonary
function in survivors of MDR TB.
To establish the impact of MDR TB and its treatment on the quality of life
of MDR TB survivors.
To assess the effect of HIV and MDR TB co-infection on pulmonary
function in MDR TB survivors.
|
USA |
2018-02-13 |
2021-02-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Yahaya Gavamukulya
ID: UNCST-2019-R001017
|
Green Synthesis and Biochemical Evaluation of Anticancer Activities of Silver Nanoparticles Conjugated Ethanolic Extracts of Leaves of Annona muricata (Graviola)
REFNo: NS43ES
General Objective
To undertake green synthesis and biochemical evaluation of anticancer activities of AgNPs-conjugated ethanolic extracts of leaves of Annona muricata (Graviola).
Specific Objectives
1. To conduct LCMS analysis of the ethanolic extracts of leaves of Annona muricata and undertake green synthesis and characterization of the extracts’ mediated AgNPs.
2. To investigate the effects of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata on the biological properties (morphology, migration, growth, and death) of selected cancer cell lines using selected assays.
3. To evaluate the effects of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata on the transcriptome for expression of cancer associated genes in selected cancer cell lines using RNA-Seq analysis.
4. Evaluation of the in vivo anticancer activities of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata against chemically induced tumours in mice models.
|
Uganda |
2018-02-13 |
2021-02-13 |
Natural Sciences |
|
Degree Award |
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