Godfrey Siu
ID: UNCST-2021-R005439
|
The impact of COVID-19 on domestic care work in Uganda
REFNo: SS770ES
1. To determine the burden and patterns of domestic care work during the COVID-19 response phase.
2. To determine the barriers and facilitators of domestic work during the lockdown.
3. To examine the effects of COVID-19 on the social, economic and family relations.
|
Uganda |
2021-04-15 |
2024-04-15 |
Social Science and Humanities |
|
Non-degree Award |
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James Katungyi
ID:
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The effect of daytime circadian thermal variability on the well-being of building occupants. A case study of office type building occupants in Kampala.
REFNo: SIR41ES
The research objective is to compare short and long-term impacts, of variable indoor thermal conditions (which mimic the outdoor variability) versus static thermal conditions, on the wellbeing of building occupants.
|
Uganda |
2021-04-13 |
2024-04-13 |
Engineering and Technology |
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Degree Award |
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Susannah Mayhew Harding
ID:
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Rapid Qualitative Research to support integrated environment, livelihoods and health programming in Uganda (“Supporting Integrated Programming”)
REFNo: HS1137ES
The research objectives are to:
1) Determine the environmental, livelihood and health challenges facing communities living in/near Rushebeya wetland;
2) Identify how, and through what structures and processes, people in these communities make decisions about and respond to identified challenges; and identify whether these responses have changed over time;
3) Examine whether there are differences in responses by age, sex or socio-economic background.
4) Identify messages and intervention activities to address the challenges felt by different groups in these communities.
|
UK |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
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Non-degree Award |
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Joseph Nkamwesiga
ID:
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Epidemiology of Peste des Petits Ruminants (PPR) in Uganda
REFNo: A103ES
General Objective:
To determine national PPR risk profiles [low, medium and high], seroprevalence and incidence of different PPRV lineages, factors that influence PPRV transmission and hence develop a dynamic PPRV transmission model and the best control intervention(s) to limit PPRV transmission in selected livestock production systems in Uganda
The specific objectives of this study are to:
i. stratify Uganda districts into different PPR risk profiles [low, medium and high] by undertaking presence only ecological niche (MaxEnt) modeling of the past PPR outbreaks, small ruminant movements and vaccination coverage data sets
ii. estimate seroprevalence of PPRV and epidemiological factors that influence PPRV transmission within and between different PPR risk profiles and small ruminant production systems
iii. estimate PPR incidence and PPRV lineages involved in different PPR outbreaks across different small ruminant production systems [or agro-ecological zones] in Uganda
iv. develop a PPRV transmission dynamic and eradication model for PPR in selected small ruminant production systems [agro-ecological zones] in Uganda using compartmentalized SEIR mathematical modeling approach
|
Uganda |
2021-04-13 |
2024-04-13 |
Agricultural Sciences |
|
Degree Award |
|
Freddy Kitutu Eric
ID: UNCST-2020-R014751
|
Strengthening Antimicrobial Stewardship, Consumption and Use in Uganda (SAMSU)
REFNo: HS1155ES
To conduct Antimicrobial Consumption and Use by ATC/DDD Methodology and the WHO AWaRE classification Antimicrobials intended for use in Humans for the Years 2017, 2018, 2019 and 2020 using Medicine Imports and Local Manufacture Data in Uganda (SCACUS)To examine health facility bottlenecks and determinants of antimicrobial use that affect antibiotic stewardship practices at outpatient departments with the aim of strengthening healthcare professionals’ AMS capability in Eastern Uganda (SAMSEU)
|
Uganda |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
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From Directly-Observed Therapy (DOT) to Video Observed Therapy (VOT): A study on the use of evidence based Digital Adherence Technologies (DAT) for improving TB Treatment outcomes
REFNo: HS1183ES
a. Active Case Finding Strategy: To study the impact of increase in case finding of drugs susceptible case in the selected 2 TB units of Kabarole and Mbarara, where the component will be tested.
b. Active Patient Compliance Toolkits: To test the efficacy of patient led adherence using mobile based Video Observed Therapy approach in improving the TB adherence rate and overall improvement in TB treatment outcomes;
c. Active Community-Led Supervision: To test the improvement in TB treatment outcomes like TB Success Rates, Cure rates and Adherence rates in the community let supervision model;
d. Active Ground Building Activities; To assess the change in knowledge, attitude and practice (KAP) level of TB patients; their family members and the community around TB and related issues.
|
Uganda |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Bruce Kirenga J
ID: UNCST-2019-R001460
|
SITUATIONAL ANALYSIS OF EXISTING CAPACITY AND RESOURCES AT MEAKERERE UNIVERSITY TO SUPPORT A RESEARCH TRAINING PROGRAM FOCUSING ON NON-COMMUNICABLE DIEASES AND AGEING AMONG PEOPLE LIVING WITH HIV/AIDS
REFNo: HS1252ES
General Objective
To describe existing research capacity, training and resources within the MakCHS that can be leveraged to design a successful NCD-HIV-Ageing training program at MakCHS
Specific Objectives
To describe existing NCD, HIV and ageing research at Makerere University and collaborating institutions within MakCHS and Mulago Hospital complex.
To define the existing NCD, HIV and ageing training activities at Makerere University and collaborating institutions within MakCHS and Mulago Hospital complex.
To outline the existing resources to support research and training on NCDs, HIV and ageing at Makerere University and other collaborating institutions within MakCHS and Mulago Hospital complex.
To define a pool of potential trainees that could be recruited for research training on NCDs, HIV and ageing at Makerere University and collaborating institutions within MakCHS and Mulago Hospital complex
|
Uganda |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
|
Non-degree Award |
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Barbara Balikuddembe Ndagire Balikuddembe
ID:
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Dental Practitioners’ Knowledge, Attitudes, and Practices Regarding Caries Risk Assessment in the Management of Dental Caries in Uganda: A Cross Sectional Study
REFNo: HS1275ES
i. To determine the knowledge of dental practitioners regarding caries risk assessment in the management of dental caries in Kampala metropolitan.
ii. To determine the attitudes of dental practitioners regarding caries risk assessment in the management of dental caries in Kampala metropolitan.
iii. To determine the practices of dental practitioners regarding caries risk assessment in the management of dental caries in Kampala metropolitan.
iv. To explore the training needs of CRA among trainers of dental practitioners in Kampala metropolitan.
|
Uganda |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
|
Degree Award |
|
Victor Musiime -
ID: UNCST-2021-R013794
|
A randomized Trial to investigate strategies to reduce mortality among HIV-infected and HIV-exposed children admitted with severe acute malnutrition in Mulago Hospital, Kampala, Uganda
REFNo: HS1277ES
Primary objective
1. To investigate whether empirical use of an antibiotic with greater antimicrobial sensitivity (ceftriaxone) than standard of care (ampicillin plus gentamicin) will reduce mortality among 300 HIV-infected and HEU children admitted with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago Hospital in a randomised controlled trial.
Secondary objectives
2. To compare the length of hospitalization, weight-for-height, weight-for-age and height-for-age z-scores between ceftriaxone versus standard of care (ampicillin and gentamicin) treatment arms.
3. To ascertain the frequency of different bloodstream bacterial pathogens and their antimicrobial sensitivities among HIV-infected and HEU children admitted with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago Hospital participating in the randomised trial.
4. To ascertain the prevalence of, and factors associated with, HIV-infection among children admitted with severe acute malnutrition at Mwanamugimu Nutrition Unit, Mulago Hospital in light of improved PMTCT approaches in a cross-sectional evaluation at admission, among 280 children.
5. To evaluate the pharmacokinetic (PK) parameters of LPV/r among severely malnourished HIV infected children using sparse PK samples. The PK parameter values obtained will then be used in pharmacokinetic-pharmacodynamic (PK-PD) models to determine a possible optimal dose of LPV/r among severely malnourished children, which could then subsequently be evaluated in a clinical trial.
|
Uganda |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
|
Non-degree Award |
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Freddy Kitutu Eric
ID: UNCST-2020-R014751
|
Exploring access to health care and medicines during COVID-19 in Mukono and Luwero districts: critical challenges and feasible policy options for the medicines retail sector
REFNo: HS1302ES
To describe the practical, policy and political barriers to including pharmacies, drug shops and private clinics in the response to COVID-19 and the means to overcome them.,. To describe how national actors and district officials would like to involve the medicines retail sector in their pandemic planning and action for COVID-19. ,To explore how the medicines retail sector in Uganda could be involved in response to COVID-19 and future outbreaks,To document the impact of the COVID-19 pandemic and public health response on the ability of women and the parents of young children in Uganda to access medicines,To document the effect of the government response to COVID-19 on supply of healthcare services/ care provision by drug shops, pharmacies and private clinics in Uganda,To describe how policy can be adapted to ensure continuity of access to essential medicines and support the involvement of the retail sector in COVID-19 activities during this and future outbreaks,To understand how the public health response to COVID-19 is shaping the supply of and access to treatment in the medicines retail sector in Uganda;,
|
Uganda |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
|
Non-degree Award |
|
Irene Mutuku M.
ID:
|
KNOWLEDGE, ATTITUDES AND PRACTICES TOWARDS COVID-19
PREVENTION MEASURES AMONG COMMUNITIES AT
SELECTED GAZETTED INTERNATIONAL
ENTRY-POINTS OF KIGEZI
SUB-REGION,
UGANDA
REFNo: SS660ES
General objective
To assess the knowledge, attitudes and practices towards COVID-19 prevention measures in communities living at gazetted international entry points of the Kigezi sub-region in Uganda.
Specific objectives
i. To establish the knowledge of the community members in selected gazette international entry points in the Kigezi region regarding measures instituted to stop the spread of COVID-19 in Uganda.
ii. To assess the attitudes of the community members in selected gazetted international entry points in the Kigezi region towards measures instituted to stop the spread of COVID- 19 in Uganda.
iii. To investigate the practices of community members in selected gazetted international entry points in the Kigezi region on measures instituted to stop the spread of COVID- 19 in Uganda.
|
Kenya |
2021-04-09 |
2024-04-09 |
Social Science and Humanities |
|
Non-degree Award |
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NEEMA NAKYANJO -
ID:
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Fishing and inland communities – understanding transmission linkages and networks
REFNo: SS698ES
a) To understand the socio-structural context of migration of high risk persons/key populations to and from high HIV prevalence Lake Victoria fishing communities and other geographic areas with high HIV-prevalence
b) To use molecular, social and epidemiological data to identify and elucidate the factors/associations of transmission linkages/networks within key and general population cohorts/groups.
c) To increase our understanding of HIV prevention and care utilization of high risk persons/key populations moving to and from places with high rates of HIV infection
|
Uganda |
2021-04-09 |
2024-04-09 |
Social Science and Humanities |
|
Non-degree Award |
|
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
|
Impact of malnutrition on pharmacokinetic of rifampicin, isoniazid, pyrazinamide and ethambutol in TB-HIV co-infected children
REFNo: HS1217ES
Primary Objective
To assess the effect of Severe Acute Malnutrition (SAM) on plasma concentration of rifampicin, isoniazid, pyrazinamide, and ethambutol in children with TB.
Secondary Objectives
1. To assess the effect of HIV-infection and antiretroviral treatment on plasma concentration of rifampicin, isoniazid, pyrazinamide, and ethambutol in children with TB and Severe Acute Malnutrition (SAM)
2. To assess whether new WHO-based dosages will achieve rifampicin, isoniazid, pyrazinamide, and ethambutol drug concentrations above the target therapeutic concentrations in HIV-TB co-infected children with and without SAM
3. To assess the effect of nutritional parameters, HIV-infection, antiretroviral treatment, and other factors (age, liver enzymes, NAT2 status) on PK parameters of rifampicin, isoniazid, pyrazinamide, and ethambutol in HIV-infected children with TB
4. To build a PK/PD relationship between drug concentrations and TB treatment outcomes
5. To assess rifampicin protein binding in relation with malnutrition and albuminemia
6. To derive an optimal dosing algorithm for rifampicin, isoniazid, pyrazinamide, and ethambutol that will adequately provide optimal exposures to malnourished and HIV infected children
|
Uganda |
2021-04-09 |
2024-04-09 |
Medical and Health Sciences |
|
Non-degree Award |
|
Eva Laker Odongpiny Agnes
ID: UNCST-2024-R004807
|
A Toll-Free Call Intervention to Improve Adverse Events Reporting in Patients On Dolutegravir in Three Health Centers in Kampala, Uganda and a Prospective Cohort Study to Describe Adverse Events to Dolutegravir at the Infectious Diseases Institute (DOLUPHARM)
REFNo: HS1263ES
A) Primary objective (Objective 1)
To determine whether a toll-free phone system for reporting of adverse events by clinicians and patients improves adverse event reporting compared to standard reporting methods using paper based or online forms by clinicians in three health centers initiating/switching patients to DTG between November 2020 and October 2021.
B) Secondary objective (Objective 2)
To determine level of uptake and the experiences of clinicians and patients with using a toll-free phone system for reporting adverse events compared to standard reporting methods using paper based or online forms in three health centers initiating/switching patients to DTG between November 2020 and October 2021
Prospective Cohort Study
A) Primary objective (Objective 3)
To describe the incidence and factors associated with occurrence of different adverse events among patients being switched/initiated on a DTG-based regimen at the IDI.
B) Secondary objective (Objective 4)
To determine whether occurrence of adverse events affects adherence to medications among patients being switched/initiated on a DTG-based regimen at the
|
Uganda |
2021-04-09 |
2024-04-09 |
Medical and Health Sciences |
|
Non-degree Award |
|
Miriam Nakalembe
ID: UNCST-2021-R014040
|
NEW APPROACHES FOR THE EARLY DETECTION OF CERVICAL NEOPLASIA
REFNo: HS1161ES
1. Determine acceptability and accuracy of a low-cost smartphone confocal micro-endoscope imaging technique for the diagnosis of CIN 2+. Confocal images will be compared against gold-standard histopathology to obtain preliminary diagnostic performance characteristics.
2. Compare various cervico-vaginal fluid (CVF) biomarkers to gold-standard histopathology for the diagnosis of CIN 2+. Qualitative and quantitative levels of biomarkers will be compared against gold-standard histopathology to obtain diagnostic performance characteristics.
|
Uganda |
2021-04-08 |
2024-04-08 |
Medical and Health Sciences |
|
Non-degree Award |
|
Susan Tino
ID:
|
Scale-Up and Capacity Building in Behavioral Science to Improve the Uptake of Family Planning and Reproductive Health Services (SupCap)
REFNo: HS1196ES
1. To test if the BSci Package can lead to an increased uptake of modern contraceptive methods improvements in gender norms, an increase in knowledge of contraceptive methods, birth spacing, and childrearing among postpartum women.
2. To find out how we effectively and efficiently replicate and scale up the BSci Package across Eastern Uganda and elsewhere.
|
Uganda |
2021-04-08 |
2024-04-08 |
Medical and Health Sciences |
|
Non-degree Award |
|
Kamya Moses
ID: UNCST-2020-R014203
|
A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa (SAPPHIRE)
REFNo: HS1239ES
Overall Objective: Our overall objective is to determine to reduce HIV incidence and to improve community health with multi-sector, scalable interventions.
Primary Objective: Reduce HIV incidence using innovative strategies for HIV prevention and treatment to simultaneously reach “persistent driver” populations.
Secondary Objectives:
1. Evaluate and optimize individual intervention component effects, alone (Phase A) and in combination (Phase B), versus control conditions on prevention coverage and HIV viral suppression
2. Assess the effect of the intervention package on other health outcomes (all-cause mortality, tuberculosis, hypertension linkage and control, heavy alcohol use and mother-to-child HIV transmission) in Phase B
3. Evaluate behavioral and other mechanistic pathways for intervention effects on proximal mediators of HIV incidence in Phase B
4. Assess the reach, effectiveness, patient and provider adoption, and fidelity and the maintenance of intervention components in Phase B
5. Use final study data to inform a strategic and sustainable investment model that maximally reduces HIV incidence and improves community health for the combination interventions tested in Phase B
|
Uganda |
2021-04-08 |
2024-04-08 |
Medical and Health Sciences |
|
Non-degree Award |
|
CARL CHRISTIAN STECKER CHRISTIAN
ID:
|
Caregiver-Assisted Oral Fluid-based HIV Screening in Children: Estimation of Acceptability, Feasibility and Effectiveness Linked to Index Testing Services in Uganda.
REFNo: HS1258ES
The purpose of this study is to evaluate the acceptability, feasibility and effectiveness of a caregiver-assisted oral fluid based HIV test to screen children for HIV. The results of this study are intended to support expanded access to HIV testing and treatment services for children, and to ensure that all newly diagnosed children are linked to clinical care.
The primary objectives of this study are to:
1. Estimate the acceptability of implementing caregiver-assisted oral fluid-based HIV screening for children as part of index testing services for HIV-positive adults.
2. Estimate the feasibility of implementing caregiver-assisted oral fluid-based HIV screening for children as part of index testing services for HIV-positive adults.
3. Estimate the effectiveness of caregiver-assisted oral fluid-based HIV screening on testing yield, return to clinic, and linkage to ART for newly identified CLHIV.
The secondary objective of the study is to:
Estimate the cost of caregiver-assisted oral fluid-based HIV screening compared to the standard costs of the existing referral to testing program, from the perspective of the health care provider.
|
USA |
2021-04-08 |
2024-04-08 |
Medical and Health Sciences |
|
Non-degree Award |
|
Leah Pauline
ID:
|
The Paradox of Being an Adolescent Girl in Uganda During a Global
Pandemic
REFNo: SS765ES
My research aims to answer the following
research question and sub-questions:
How do adolescent girls in Uganda navigate the liminal period of COVID-19 when their
educational aspirations of empowerment are put on hold and they face exacerbating
pressures to abide by gender roles/expectations?
Sub-questions:
1- How do high school drop-outs in Uganda differ before and after the onset of the COVID-19 pandemic?
2- What factors influence adolescent girls’ reproductive health and
whether or not they return to school?
3- How do adolescent girls’ future aspirations play a role in their
continuation of schooling?
4- How do adolescent girls interpret peer drop-outs as they navigate their
own decision to continue their education or drop-out?
|
USA |
2021-04-08 |
2024-04-08 |
Social Science and Humanities |
|
Degree Award |
|
Matthew Cooper
ID: UNCST-2021-R013904
|
Legacy effects of land-use on tropical soils as constraints on the restoration success and service provision of tropical forests in Uganda
REFNo: NS157ES
The research subject of this project will be the evaluation of soil fertility, soil degradation, C sequestration in both soils and plants, and biodiversity along
tropical secondary forest successions in Western Uganda in three work
packages.
|
UK |
2021-04-06 |
2024-04-06 |
Natural Sciences |
|
Degree Award |
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