Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Moses  Mulumba
ID: UNCST-2021-R013832
National Study on the impact of contentious issues and masculinities on the realization of Sexual and Reproductive Health and Rights in Uganda
REFNo: SS537ES

General Objective: To generate evidence for SRHR advocacy and programming in Uganda
Specific objectives are;
1. To document the journey of the Sexual and Reproductive Health and Rights movements in Uganda
2. To explore the relationship between masculinities and sexual reproductive health and rights
3. To examine the influence of contentious issues like abortion, and LGBTQI on the realization of SRHR

Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
Evaluation of the Clinical Performance of a Plastic Capillary Tube with the Determine HIV-1/2, Determine HIV Early Detect and Determine HBsAg 2 Rapid Tests
REFNo: HS895ES

The primary objective of this study is to evaluate the performance of a new plastic capillary tube for the transfer of a capillary finger-stick blood sample to 3 rapid test platforms; the Determine HIV-1/2 test platform, the Determine HIV Early Detect test platform and the Determine HBsAg 2 platform. The HIV and HBsAg results obtained using the new plastic capillary tubes to transfer capillary whole blood to the test devices will be evaluated against the HIV and HBsAg results obtained using a micropipette to transfer a whole blood venous sample from the EDTA Vacutainer tube to the same testing platforms, with discrepant result resolution where required. The new plastic capillary tubes have been verified in an internal performance study at the Abbott laboratories.
UK 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Edward  Bitarakwate
ID:
Evaluation of Patient and Program Outcomes Achieved through EGPAF-supported Integrated HIV and TB Prevention, Care, and Treatment Programs in Uganda
REFNo: HS930ES

Primary Objectives:
1.To determine patient and program outcomes for children, adolescents and adults receiving HIV and TB services in EGPAF supported facilities and through EGPAF supported programs.

Secondary Objectives:
1. To determine outcomes of HIV testing strategies targeted at identifying HIV positive children, adolescents, and adults in facilities and the community including the number and proportion identified as HIV-positive, linked to HIV services, and initiated on ART in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome along the testing to treatment cascade.

2. To determine clinical and laboratory outcomes among HIV-positive children, adolescents and adults enrolled in HIV services such as morbidity (including coinfections), mortality, ART regimen, ART adherence, retention in care, viral suppression, and disease progression in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome, including baseline clinical characteristics before initiating ART.

3. To determine the outcomes of HIV prevention activities (including PMTCT) among pregnant women, discordant couples, adolescents and other key and priority populations in facilities and the community including the number accessing prevention services by risk category, retention in services, and seroconversion rates.
a. To determine individual, population, and program characteristics/factors associated with the HIV prevention outcomes.

4. To determine clinical and laboratory outcomes among children, adolescents and adults accessing TB screening/diagnosis, prevention, and treatment services such as HIV/TB coinfection rates, initiation and adherence to IPT, initiation and adherence to TB treatment, retention in care, treatment outcomes for drug resistant TB, mortality.
a. To determine individual, population, and program characteristics/factors associated with each outcome.

Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
“Assessment of circulating proteins in Ugandan tuberculosis household contacts for latent TB infection biomarker development: Version 1.0 dated 14 Sept 2020”
REFNo: HS958ES

Refine our protein signature to function in HIV-positive persons, incorporating cytokine and chemokine markers as needed.
2. Refine our protein signature to identify Mtb infection that has developed within a 6-month timeframe.

Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Esther Nanfuka Kalule
ID:
Livelihood Resilience During the COVID-19 Lockdown: Practices of Informal Sector Populations in the Urban and Peri-urban Settings of Kampala and Wakiso Districts
REFNo: SS619ES

The study will specifically:
• Examine the current livelihood practices and resources among urban informal sector workers in the context of restricted mobility and social distancing
• Examine the opportunities and challenges for vulnerable urban informal sector workers to negotiate and reconfigure livelihood sources including social networks and social capital for support in a lockdown situation
• Assess the most valued livelihood sources (assets, capabilities, activities) under the lockdown and preferred areas of allocating available resources among different categories of the informal urban population
• Examine the potential and perceived risks (including public health) of the livelihood activities undertaken during the COVID-19 lockdown

Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
ARTHUR  SEKIZIYIVU BRIAN
ID:
END-LINE EVALUATION OF AN HIV PREVENTION PROJECT IMPLEMENTED BY UGANDA PEOPLE’S DEFENSE FORCES AND PACE
REFNo: HS989ES

I. Measure changes in the knowledge, attitudes and practices among the military and AGYW to adopt and sustain positive behavior change.
II. Identify challenges, innovations, lessons, and success stories across the interventions
III. Identify the opportunities to integrate prevention interventions within (into) an HIV care program

Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Hannington Odongo Jawoko
ID: UNCST-2024-R002457
The Relationship between Social Governance and Smallholder Farmer Socio-Economic Resilience: Moderating Effects of Pluralistic Agriculture Extension Service Provision in Northern Uganda
REFNo: A78ES

To investigate the moderating effects of perceptions of the quality of pluralistic agricultural extension services provision on social governance exhibited in participatory local government planning and budgeting process.

To examine the influence of social governance exhibited in participatory local government planning and budgeting process on the values and needs of smallholder farmers in northern Uganda.

To assess the impacts of perceptions of the quality of pluralistic agricultural extension services provision on socio-economic resilience of smallholder farmers in northern Uganda.

To examine the impacts of social governance exhibited in participatory local government planning and budgeting process on smallholder farmer’s socio-economic resilience in northern Uganda.

Uganda 2020-11-09 2023-11-09 Agricultural Sciences Degree Award
Anthony Mugeere Buyinza
ID:
THE IMPRINT OF EDUCATION: A LONGITUDINAL COHORT STUDY OF AFRICAN ALUMNI OF THE MASTERCARD FOUNDATION SCHOLARS PROGRAM
REFNo: SS543ES

(i) To provide evidence at multiple levels on the individual, structural, contextual and programmatic factors that mediate Scholars’ outcomes especially with regards to “return”, “giving back”, “transformative and ethical leadership”

(ii) To assess the imprint of education on the lives of individuals, communities and societies in contexts such as those on the African continent in which Mastercard Foundation (MF) provides scholarships.

(iii) To examine the links between socio-economic inclusion, education and development.

(iv) To understand what works and why, as well as what might be done to improve the MSP and maximise the impact of Scholars as agents in the social and economic transformation of the African continent (by considering their social networks, support and training received, the way in which institutions contributed to their success, and their employment and employment creation trajectories).
Uganda 2020-11-09 2023-11-09 Social Science and Humanities Non-degree Award
Augustine Ssevviri Kaddu Musisi
ID:
Using the Health Belief model to increase the level of knowledge, attitudes and practices of COVID-19 prevention measures in Wakiso district, Uganda
REFNo: HS883ES

1.0 Main Objective
To understand the level of adherence towards the COVID-19 guidelines and assess the knowledge and attitudes regarding COVID 19 in order design a behavioral change intervention that enhances knowledge and promotes compliance to the prescribed COVID-19 practices at the grassroots level in Wakiso district, Uganda
1.1 Specific Objectives
• To determine the level of knowledge about the prevention of COVID-19 among the people in Wakiso district
• To understand community attitudes towards the prevention of COVID-19 in Wakiso district
• To determine the level of adherence to COVID-19 prevention guidelines among community members in Wakiso District
• To design a behavioral change communication intervention for improving people’s knowledge, attitudes and level of adherence towards COVID-19 guidelines

Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
willy waninga
ID:
The use of ICT in the teaching of integrated science in Primary Teachers' Colleges in Uganda: A case of Four Primary Teachers' Colleges
REFNo: SS594ES

1. To find out ICT tools used by science tutors in teaching integrated science education
2. To find out how science tutors use technological content knowledge in planing integrated science education lessons.
3. To find out how integrated science education tutors integrate technological content knowledge in the pedagogy of science education.
Uganda 2020-11-09 2023-11-09 Social Science and Humanities Degree Award
Herbert Kayiga Kayiga
ID:
IMPACT OF COVID-19 PANDEMIC ON MATERNAL AND NEWBORN HEALTHCARE SERVICE DELIVERY IN PRIVATE AND PUBLIC FACILITIES IN UGANDA
REFNo: HS924ES

STUDY OBJECTIVE:
To determine the impact of COVID-9 pandemic on the provision of maternal and newborn services in Kampala, Uganda

SPECIFIC OBJECTIVES:
1. To determine the quality of maternal and newborn service provision in Kampala, Uganda before the COVID-19 pandemic.
2. To determine the quality of maternal and newborn service provision in Kampala, Uganda during the COVID-19 pandemic.
3. To seek understanding of the experiences of the health workers as they provide maternal and newborn services in Kampala, Uganda.
4. To seek understanding of the pregnant and breastfeeding mothers’ experience as they seek maternal and newborn services in Kampala, Uganda.

Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Matthew  Cotten Louis
ID:
Local sequencing of SARS-CoV-2 from Uganda COVID-19 cases
REFNo: HS936ES

To document the transmission dynamics of COVID-19 in Uganda using full viral genome sequencing
USA 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
Title: Analysis of A Tool To Assess Psycho Social Spiritual Healing: Cognitive Interviewing
REFNo: HS957ES

1. To determine the face and content validity of the NIH-HEALS

2. To determine the comprehensiveness, comprehensibility and acceptability of the NIH HEALS in Uganda
Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Jane  Kabami
ID: UNCST-2021-R012588
Leveraging the HIV platform for hypertension control in Uganda (INTEGRATED HIV/HTN)
REFNo: HS979ES

1 To determine the effectiveness of an integrated HIV/HTN care model on HTN and dual
HIV/HTN control among adult patients in HIV clinics.
2 To assess the barriers and facilitators of the integrated HIV/HTN care model for HIV
patients at different levels.
3 To determine the cost, cost-effectiveness and incremental gain costs of the integrated
HIV/Hypertension care model approach
Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Grace Edwards
ID:
An exploration of the need for Nursing and Midwifery Leadership Capacity Building in Uganda
REFNo: HS562ES

The study is aimed at exploring the leadership training needs for nurses and midwives in Uganda, in order to develop recommendations for developing nursing and midwifery leaders in Uganda and draft a leadership training programme.
UK 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Moses Adroma
ID: UNCST-2019-R000360
INCIDENCE & PREDICTORS OF ABNORMAL RENAL FUNCTION THREE MONTHS AFTER DELIVERY AMONG PREECLAMPSIA SURVIVORS AT MULAGO HOSPITAL
REFNo: HS341ES

To determine the incidence and predictors of abnormal renal function three months after delivery among preeclampsia survivors at Mulago Hospital.
Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Kintu  Mugagga
ID:
Comparative Assessment of Anatomical and Neuro-Cognitive Characteristics Between Vaginally And Caesarean Section Delivered Children of 1-2 years Age At Mbarara Regional Referral Hospital, South-Western Uganda
REFNo: HS397ES

i) To describe the differences in the head-size and body height between VD and CSD children at 1-2 years of age born at Mbarara Regional Referral Hospital.


ii)To describe the differences in neurocognitive characteristics between VD and CSD children at 1-2 years of age born atMbarara Regional Referral Hospital.


iii)To describe the perinatal and socio-demographic characteristics of the mothers to the VD and CSD childrenof 1-2 years of age delivered at Mbarara Regional Referral Hospital.

Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
Owning our future through community engagement: enhancing uptake of COVID-19 prevention and mitigation measures”
REFNo: HS858ES

Specific Objectives
1. Ascertain the:
a) Prevailing attitudes and perceptions towards COVID-19 mitigation measures and community response and adaptation (behaviours, practices) to the “new social norms” imposed by the emergency response;
b) Short-term socioeconomic impact and community coping mechanisms
2. Develop and implement a community engagement intervention for enhancing uptake of the recommended COVID-19 public health and social mitigation measures.
3. Evaluate the effects of the intervention developed in 2 above on acceptance and uptake of the COVID-19 prevention and mitigation measures.

Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Martha Nabadda
ID:
A qualitative case study exploring health workers’ perspectives on facilitators and barriers to comprehensive management of sickle cell disease in young adults aged 18 – 25 years accessing primary care in Uganda.
REFNo: HS616ES

i. To investigate the facilitators and barriers to comprehensive management of sickle cell disease, using a focused group discussion and ten semi-structured, in-depth interviews with healthcare workers at three sickle cell clinics in Uganda.

ii. To explore the care and support needs specific to young adults with sickle cell disease accessing the health system at the point of primary care.

iii. To make care and policy recommendations for the Ministry of Health to improve guidelines for the provision of sickle cell disease care in public health facilities in Uganda.
Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Abner Tagoola
ID: UNCST-2021-R013446
Enhancing maternal participation in neonatal hospital care using an adapted Family Integrated Care (FICare) program
REFNo: HS632ES

The purpose of this study is to adapt and test a model of enhanced maternal participation (FICare) in a neonatal hospital unit in Uganda. This is with the goal of increasing the level of patient monitoring and ultimately improving the quality of care that sick and small newborns receive in the hospital. Specifically, the study is
1. To determine the acceptability of implementing an adapted FICare model, specifically maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase I)
2. To test the feasibility of implementing maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase II)

Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
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