Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
 SEARCH: SMS Electronic Adolescent Reminders for Completion of HPV vaccination in Uganda
REFNo: SS822ES

This protocol is solely for text and voice phone message and intervention development for a subsequent feasibility trial to improve adherence to HPV vaccination schedules in Kampala City., 2: Develop and pre-test HPV vaccine reminders with the target population, 1: Identify desired HPV vaccine text message reminder content (and parallel automated phone reminders) using key informant interviews ,
 Uganda 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
WINTERS MUTTAMBA
ID:
A HEALTH SYSTEMS ANALYSIS AND MODELLING OF METHODS TO MAXIMIZE UPTAKE AND UTILIZATION OF ADVANCED DIAGNOSTICS IN LOW- AND MIDDLE-INCOME COUNTRIES – THE CASE OF COVID-19
REFNo: HS1337ES

1.To quantify the degree of uptake & utilization of COVID-19 diagnostic tests in Uganda, Rwanda, Kenya and UK
2.Map the pathways of uptake and ramping up COVID-19 testing in the study countries.
3.To characterise micro level and macro level factors affecting uptake and utilisation of COVID-19 diagnostic tests in Uganda, Kenya, Rwanda and UK
4.Modelling data obtained in 1) and 2) to identify best models for maximizing uptake of advanced diagnostic tests in health emergencies.
Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-degree Award
Ivaibi Charles
ID:
SELECTED CORRELATES OF WORK ENVIRONMENT AND HEALTH SERVICES DELIVERY IN HEALTH CENTRES IN BUSOGA REGION,EASTERN UGANDA
REFNo: SS798ES

(a) To establish the relationship between Support Supervision and Health Services Delivery at Health Centers in Busoga region.
(b) To study the relationship between Physical Work Environment and Health Services Delivery at Health Centers in Busoga region.
(c) To get in-depth information about the relationship between Information Management and Health Services Delivery at Health Centers in Busoga region.
(d) To design a model that will guide effective Health Services Delivery at Health Centers in Busoga region.
 Uganda 2021-06-04 2024-06-04 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Namuga
ID:
INVESTIGATING THE POTENTIAL OF BIOACTIVE GAUZE DRESSING IMPREGNATED WITH HERB-LOADED NANOPARTICLES IN FACILITATING WOUND HEALING
REFNo: HS1393ES

The main aim of this work is to functionalise the gauze dressing using herb loaded nanoparticles to enable faster wound healing in excision wound models established in rats.

Specific objectives
1) To determine the antibacterial activity of Bidens pilosa L., Hoslundia opposita Vahl and Ageratum conyzoides L., plant extracts.
2) To determine the effect of the most efficacious antibacterial herbal extract on wound healing rate using excision wound models in rats.
3) To determine the effect of nano encapsulation of the herbal extract using biopolymers, on its antibacterial activity and wound healing rate.
4) To evaluate the effect of incorporating herb loaded nanoparticles into the gauze dressing on its antibacterial activity and wound healing rate.
5) To assess the effect of the herb loaded nanoparticles on the performance characteristic of the gauze dressing.

Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Patrick  Ogwok
ID:
Validation of the food literacy questionnaire among the adult population (18 to 69 years) living in urban Uganda
REFNo: HS1415ES

To evaluate the concurrent validity, assessing capacity of the food literacy questionnaire to distinguish between subgroups with a higher or lower food literacy.,To evaluate criterion validity by exploring associations of the food literacy questionnaire with fruit and vegetable consumption and healthy eating self-efficacy,To evaluate the reliability of a food literacy questionnaire within the adult population (18 to 69 years) living in urban Uganda,To evaluate the construct validity of a food literacy questionnaire against Prime Diet Quality Score within the adult population (18 to 69 years) living in urban Uganda.,To evaluate the face validity of a food literacy questionnaire within the adult population (18 to 69 years) living in urban Uganda ,To evaluate the content validity of a food literacy questionnaire (18 to 69 years) living in urban Uganda,To validate the food literacy questionnaire with respect to healthy eating within the adult population (18 to 69 years) living in urban Uganda. ,
 Uganda 2021-06-04 2024-06-04 Medical and Health Sciences Non-Clinical Trial Degree Award
OTIM   ANYONI GODFREY
ID:
EFFECT OF TILLAGE AND SOIL COVER ON WEEDS IN SMALL HOLDER CONSERVATION AGRICULTURAL SYSTEMS
REFNo: A128ES

1- To compare three seed bank estimation techniques for determining weed seed density and species composition under different tillage practices and soil cover
2- To determine the effect of tillage practice on weed density, diversity and crop performance under CA systems
3- To assess the influence of crop residue and cover crop on weed density, diversity and crop performance under CA systems
4- To determine the effect of the intercrops on overall crop performance under CA systems


 Uganda 2021-06-01 2024-06-01 Agricultural Sciences Non-Clinical Trial Degree Award
Pauline Harding
ID:
Ritual, Identity and Ideology: Constructing the Past in Sub-Saharan Africa
REFNo: SS258ES

I am investigating how the past is manipulated to support present-day ideological agendas in sub-Saharan Africa, in order to understand the ways in which new histories are constructed to reinforce and legitimate group identities and ideologies. I will assess where such constructions ¬– for example at museums, educational institutions and heritage sites, and through intangible heritage displays and local neo-traditional (ritual) activities – reveal disparities between academic renderings of the past and histories that are generated by, and for the use of, the public. I will also assess the active role of heritage sites and intangible heritage practices – and therefore the social responsibilities of archaeologists and heritage workers – in shaping societies in sub-Saharan Africa today; and help archaeologists to recognise and appreciate that the past is evolving in the present, independent of their own work and an aging base of historical knowledge. Uganda is a particularly interesting example of this because, while recent historical work there has been limited, an explosion of newly constructed local histories serves increasingly to distort the historical record. The research will generate important information which will be useful to sites including the Uganda Museum as a source of data and debate as they plan their future development.
 UK 2021-05-28 2024-05-28 Social Science and Humanities Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 Describing the effect of the covid-19 pandemic on tuberculosis care in Uganda
REFNo: SS820ES

To determine the association between access to TB inpatient care services, respiratory symptoms and QoL of patients diagnosed with TB during different phases of the COVID19pandemic,To assess barriers and enablers to accessing TB diagnostic and treatment services during the different phases of the pandemic.,To assess sociodemographic differences between patients accessing TB care services during different phases of the COVID 19 pandemic ,To describe characteristics of patients accessing TB care during different phases theCOVID19 pandemic and to identify enablers and barriers to care seeking during the different phases of the pandemic.,
 Uganda 2021-05-28 2024-05-28 Social Science and Humanities Non-degree Award
Hamson Kanyesigye
ID:
ASSESSMENT OF INTRAPARTUM REFERRALS AND USE OF MOBILE PHONE TECHNOLOGY TO IMPROVE MATERNAL-FETAL OUTCOMES IN SOUTH WESTERN UGANDA
REFNo: HS543ES

General Objective
To assess Maternal Referral processes between Health centre IVs and Mbarara Regional Referral Hospital, and effect of mobile phone technology on maternal and fetal outcomes among referred patients.
Specific objectives
1. To describe patient referral processes between Health centre IV in Isingiro district and Mbarara Regional Referral Hospital.
2. To establish acceptability of phone based intervention among health workers at lower level health units

3. To establish the effect of a phone based intervention on maternal and perinatal deaths among Intrapartum referrals

4. To compare the rates of maternal near-miss conditions and other poor fetal outcomes besides death across study arms

5. To identify the causes of delay following a phone based intervention

 Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Degree Award
EDWINAH ATUSINGWIZE
ID: UNCST-2023-R007893
 Alcohol and Social Media use among university students: Perceptions, patterns and experiences, and the feasibility of social media based interventions for alcohol prevention
REFNo: HS849ES

1. To assess prevalence, patterns and associations of alcohol and social media use among university students
2. To explore university students’ perceptions about alcohol and social media use
3. To explore experiences of university students regarding alcohol and social media use
4. To explore student perspectives on possibilities and opportunities of using social media based interventions for alcohol prevention among university students

Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Non-degree Award
Agapitus Kato Babumba
ID: UNCST-2021-R013866
 Evaluation of the feasibility of SumiShield™ 50WG Insecticide use in the control of malaria vectors in COVID-19 patients’ isolation centres in Uganda
REFNo: HS1256ES

1. To determine the efficacy and residual activity of SumiShield™ 50WG insecticide against malaria mosquitoes on plastered and painted wall surfaces in COVID-19 isolation centres in Uganda.

2. To determine the susceptibility of wild Anopheles gambiae mosquitoes to SumiShield™ 50WG and other commonly used mosquito insecticides in the study area.
 Uganda 2021-05-27 2024-05-27 Medical and Health Sciences Non-degree Award
Irene Kahimakazi
ID:
Prevalence and factors associated with gestational diabetes mellitus among women attending antenatal care at Mbarara Regional Referral Hospital
REFNo: SS854ES

1. To determine the prevalence of gestational
diabetes mellitus among women attending antenatal
care clinic at Mbarara Regional Referral
Hospital South Western Uganda
2. To establish the factors associated with
gestational diabetes mellitus among women
attending antenatal care clinic at
Mbarara Regional Referral Hospital, south
western Uganda

 Uganda 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Phocas Nyandwi -
ID:
Effect of Firm Financial Strength Factors on Income Retention of General Insurers in East Africa
REFNo: SS829ES

To determine the moderating effect of firm size on the relationship between firm financial distress factors and income retention of General insurers in East Africa,To establish the effect of earnings volatility on income retention of General insurers in East Africa,To assess how liquidity affects income retention of General insurers in East Africa,To investigate the effect of leverage on income retention of General insurers in East Africa,To determine the effect of capital adequacy on income retention of General insurers in East Africa,The general objective of the study is to investigate the effect of firm financial strength factors on income retention of General insurers in East Africa.,
 Burundi 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Arunga
ID:
Management of microbial keratitis by private pharmacies in Uganda: a study of knowledge, attitude and practice
REFNo: HS1082ES

1. To determine the Knowledge of private pharmacy workers in Uganda in the management of Microbial Keratitis.
2. To describe the current practice for the management of Microbial Keratitis among private pharmacies in Uganda .
3. To explore ways to engage local pharmacy attendants to improve referral of patients with suspected Microbial Keratitis.

 Uganda 2021-05-25 2024-05-25 Medical and Health Sciences Non-degree Award
Dao Ho
ID:
Palliative Care Needs Assessment in the Emergency Department in Kiruddu Hospital
REFNo: SS796ES

Objective 1: Describe the prevalence of palliative care needs among emergency care patients. In order to assess this objective, we will conduct a palliative care needs survey with patients and health care workers in the Kiruddu Hospital Emergency Department. Objective 2: Explore and illustrate identifiable strengths as well as barriers to delivery of palliative care in the emergency department. In order to assess this objective, we will conduct one-on-one interviews with health care workers in the Emergency Department to further explore this topic.
 USA 2021-05-24 2024-05-24 Social Science and Humanities Non-Clinical Trial Degree Award
Gilbert Sendugwa Sendugwa
ID:
Towards Gender Balance: Understanding the Barriers and Solutions to Include Women-Led Businesses in East Africa
REFNo: SS712ES

This research will document policies and practices that exclude and include women-led businesses in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda. Specifically, it aims to: - Understand the participation of and challenges facing women-led businesses and sole proprietorships in the five countries and regionally. - Identify measures being implemented or tested to improve fairness and inclusion of women in public procurement in the selected countries. - Assess the effectiveness of the measures put in place by specific governments to improve fairness and inclusion. - Recommend actionable changes to improve the current situation, based on the findings of the research and international best practice.
 Uganda 2021-05-21 2024-05-21 Social Science and Humanities Non-degree Award
Joannah Nalwoga
ID: UNCST-2024-R002651
 GROUP B STREPTOCOCCUS GENITAL COLONIZATION PATTERNS AMONG NON- PREGNANT WOMEN OF REPRODUCTIVE AGE AT KAWEMPE NATIONAL REFERRAL HOSPITAL
REFNo: HS728ES

General objective
To determine how colonization with GBS changes over time among non-pregnant women of reproductive age and how the changes correlate with the host immunity
Specific objectives
1. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were uncolonized at baseline
2. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were colonized at baseline

3. To determine whether the concentration of GBS IgG in serum correlates with the concentration of GBS IgG at the vaginal mucosa
4. To determine whether we can predict colonization from GBS IgG concentration in blood
5. To determine whether we can predict colonization from GBS IgG concentration in the vaginal mucosa

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Hellen Kinyi Wambui
ID:
“Effect of varying ratios of dietary macronutrients on immune system function of Swiss albino mice”
REFNo: NS159ES

i. To assess the effects of varying macronutrient ratios on the nutrition status of Swiss albino mice
ii. To evaluate the effects of varying macronutrients ratios on leucocyte count, neutrophil adhesion and cytokine production of Swiss albino mice
iii. To determine the effects varying ratios of macronutrients on the production of pro-inflammatory (TNF-α, IFN-γ, IL-6) and anti-inflammatory (IL-10) cytokines in Swiss Albino mice challenged with lipopolysaccharide
iv. To evaluate the effects of varying macronutrients ratios on delayed -type hypersensitivity and antibody titers of Swiss albino mice challenged with cow red blood cells (CRBC)

 Kenya 2021-05-20 2024-05-20 Natural Sciences Degree Award
Enock Matovu
ID:
Development and Evaluation of Recombinant SARS-CoV-2 Spike and Membrane Protein-Based Sub-Unit Vaccines
REFNo: NS146ES

(i) To express recombinant subunits of the RBD region of the spike protein and the M protein
(ii) To characterize the humoral and cell mediated immune response generated by the RBD region and the M protein in mouse models
(iii) To determine the safety of the vaccine candidates in mouse models
(iv) To determine the efficacy of the potential candidate vaccine in mice

 Uganda 2021-05-20 2024-05-20 Natural Sciences Non-degree Award
Lena Mpalampa
ID:
FACTORS ASSOCIATED WITH PROVISION OF PHYSICAL ACTIVITY IN PRIMARY SCHOOLS IN MAKINDYE DIVISION IN KAMPALA
REFNo: SS768ES

5. To establish the school related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,4. To establish the class related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,3. To ascertain the teacher related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,2. To describe the various types of physical activity offered in primary schools in Kampala during the school term,1. To determine the proportion of schools offering sufficient time for PA among primary schools in Kampala during the school term,To analyse the factors associated with insufficient physical activity offered in primary schools in Makindye Division in Kampala during the school term.,
 Uganda 2021-05-20 2024-05-20 Social Science and Humanities Degree Award
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