Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ivan Segawa
ID: UNCST-2021-R012795
Optimizing Community-Pharmacy PrEP Delivery for Cisgender Female Sex Workers in Uganda
REFNo: HS6178ES

Aim 1: Compare the potential reach and accessibility of PrEP services through community retail pharmacies and PrEP facilities in Kampala. Aim 2: Evaluate pharmacy capacity and staff perspectives on delivering PrEP through community retail pharmacies in Kampala.
Uganda 2025-07-08 11:22:09 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Assessment of Pharmacovigilance Systems, Knowledge and Reporting in public health facilities. A Cross-sectional Assessment
REFNo: HS6195ES

i) To evaluate functionality of PV systems in public health facilities in Uganda. ii) To evaluate current PV knowledge at public health facilities in Uganda. iii) To establish evaluate the current pharmacovigilance reporting rates in public health facilities in Uganda. iv) To establish the factors influencing pharmacovigilance knowledge among health facilities practitioners in public health facilities in Uganda. v) To establish the factors influencing the reporting rates of ADRs/AEFI in public health facilities in Uganda.
Uganda 2025-07-08 11:17:16 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Antimicrobial Use Surveillance in Public Hospitals in Uganda: A Retrospective Cross-sectional Assessment
REFNo: HS6197ES

a) To assess the compliance to treatment guidelines in antimicrobial use in outpatient departments in public hospitals in Uganda b) To assess the compliance to treatment guidelines in antimicrobial use in inpatient departments in public hospitals in Uganda c) To assess the current performance of antimicrobial prescribing indicators in outpatient departments in public hospitals in Uganda d) To assess the current performance of antimicrobial prescribing indicators in inpatient departments in public hospitals in Uganda.
Uganda 2025-07-08 11:15:06 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Pebalo Pebolo
ID: UNCST-2022-R010630
Towards understanding maternal health for youth with Disabilities in Uganda
REFNo: HS6070ES

To explore experiences and perceptions of healthcare providers regarding the provision of maternal healthcare services to Female Youth with Disabilities in Uganda.,To document the perspectives of Female Youth with Disabilities regarding their experiences of accessing maternal healthcare services in Uganda.,To explore the lived experiences of pregnancy and childbirth among Female Youth with Disabilities in Uganda.,To synthesize evidence on access to maternal healthcare services for Female Youth with Disabilities in Sub-Saharan Africa.,This study seeks to understand the maternal health for FYWD based on their own experiences and perceptions and those of the maternal healthcare providers in Uganda. The knowledge and insight generated will contribute to improving the maternal health and healthcare services for WWD particularly FYWD in Uganda and other low- and middle-income countries,
Uganda 2025-07-08 11:12:51 2028-07-08 Medical and Health Sciences Non-Clinical Trial Degree Award
EGIRU EREGU EMMA ISAIAH
ID: UNCST-2021-R012653
PREVALENCE, RISK FACTORS AND OUTCOMES OF LOW BIRTH WEIGHTS AMONG NEONATES; A RETROSPECTIVE STUDY AT KAYUNGA REGIONAL REFERRAL HOSPITAL
REFNo: HS6137ES

Prevalence of low birth weight among the admissions in the neonatal unit What are the risk factors for low birth weight in kayunga What are the outcomes of admitted low birth weight
Uganda 2025-07-08 11:10:17 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ian Munabi
ID: UNCST-2023-R007147
EVALUATION OF THE MASTER OF SCIENCE IN BIOETHICS PROGRAM IMPLEMENTATION FROM 2015 -2024
REFNo: HS6089ES

ii. To review and document the outputs and implementation of the Master of Science in Bioethics curriculum at MakCHS over the last ten years. ,i. To examine stakeholder perspectives on the Master of Health Science in Bioethics program’s implementation. ,
Uganda 2025-07-08 11:05:32 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Baptist Asiimwe
ID: UNCST-2021-R013716
Factors influencing the quality of nursing care (QNC) among nurses and their patients’ perspectives in tertiary hospitals in Uganda: A mixed method study.
REFNo: HS6072ES

1) Determine the nurses' perceived level of QNC in tertiary hospitals in Uganda.
2) Establish the factors associated with nurse-perceived levels of QNC in tertiary hospitals in Uganda.
3) Determine the patients’ level of satisfaction with QNC and associated factors in tertiary in Uganda.
4) To explore the patient’s and nurses’ perceptions of nursing care received from tertiary hospitals in Uganda.

Uganda 2025-07-08 11:00:32 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hosea Kiprotich
ID: UNCST-2024-R002048
DEVELOPMENT OF AN IN-HOUSE PROTOCOL FOR MEASUREMENT OF HEMOGLOBIN FROM DRIED BLOOD SPOTS
REFNo: NS944ES


GENERAL OBJECTIVE

To establish a method for the measurement of haemoglobin from DBS.

SPECIFIC OBJECTIVES

1. To develop and optimize a protocol for measurement of Hb from dried blood spots.
2. To evaluate assay performance for hemoglobin measured in DBS eluate: inter and intra- assay variation, linearity, lower limit of detection and accuracy.
3. To determine the effect of storage temperature, time, and humidity on the performance characteristics of Hb measurement using DBS

Uganda 2025-07-08 10:47:58 2028-07-08 Natural Sciences Non-Clinical Trial Degree Award
Paul Edabu
ID: UNCST-2025-R016842
Socio-ecological factors and mental health of refugee children aged 10 to 17 years in Imvepi settlement-Terego District, West Nile region
REFNo: SS3792ES

1. To examine the prevalence of mental health issues among refugee children in West Nile region.
2. To explore the socio-ecological risk factors contributing to mental health issues in refugee children in West Nile region.
3. To investigate the protective factors and coping mechanisms that support the mental health of refugee children in West Nile region.
4. To establish the effectiveness of current community and systemic interventions to support the mental health of refugee children in West Nile region

Uganda 2025-07-08 10:36:02 2028-07-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Use of Remnant Clinical Samples from Health Facilities for Micronutrient Surveillance in Uganda
REFNo: HS6218ES

3.Determine the prevalence micronutrient deficiency using remnant clinical samples ,2. Analyze remnant clinical samples for micronutrient and inflammatory biomarkers using a multiplex assay,1.Establish a mechanism for acquisition, storage and transportation of remnant clinical samples from health facilities ,
Uganda 2025-07-07 13:37:02 2028-07-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Lubanga
ID: UNCST-2025-R018596
Displacement, Mental Health, and Access to Care: Understanding Women Refugee’s Well-being in Urban Uganda
REFNo: SS3943ES


Investigate the primary mental health and psychosocial support challenges faced by refugee women in Kampala.

Examine the structural barriers (e.g., documentation requirements, bureaucratic delays, geographic access) that hinder mental health care access.

Identify facilitators and resilience factors that support mental well-being and access to mental health and psychosocial support services.
Uganda 2025-07-04 15:20:27 2028-07-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aidah Nanvuma
ID: UNCST-2024-R015734
Assessing Health Care Providers Knowledge, Attitudes, and Practices on Sexually Transmitted Infections Post Exposure Prophylaxis in Urban Clinics in Kampala, Uganda.
REFNo: HS6083ES

1. Assess knowledge of STI PEP among HCPs in urban health facilities in Uganda. 2. Evaluate attitudes towards STI PEP among HCP in urban health facilities in Uganda. 3. Characterise current practices related to STI PEP among HCP in urban health facilities in Uganda.
Uganda 2025-07-04 14:27:02 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Kizito
ID: UNCST-2025-R017731
From shadows to spotlight: Behavioral observation of East African pottos (Perodicticus ibeanus) in Kibale National Park, community knowledge and awareness about pottos.
REFNo: NS950ES

To investigate the behavioral repertoire, and substrate use, of pottos in Kibale National Park and adjacent villages, assess community knowledge and awareness of people living near the park about pottos, and conduct conservation education
Uganda 2025-07-04 14:18:55 2028-07-04 Natural Sciences Non-Clinical Trial Non-degree Award
Salim Kombo
ID: UNCST-2023-R005870
OPTIMIZING STRATEGIES FOR PROSOCIAL BEHAVIOR IN UGANDA - A SOCIAL NETWORK STUDY
REFNo: SS4005ES

Descriptive Social Network Study: Assess the relationship between network structure and pro-social engagement, focusing on network density, centrality, homophily, and bridging ties. Qualitative Study: Investigate the dissemination of pro-social engagement information, identifying effective channels, key information injectors, motivators, barriers, and incentives for increasing engagement.,Descriptive Social Network Study: Network Structure and Engagement Correlation: Assess the density and structure of social networks and correlate them with pro-social engagement levels. Centrality and Motivational Influences: Identify the centrality of highly engaged and committed individuals and key motivators within the networks. Homophily and Bridging Ties: Analyze the extent of homophily in pro-social engagement profiles and identify key individuals who bridge different engagement levels. Qualitative Study: Information Dissemination and Effective Channels: Investigate how community monitors disseminate pro-social engagement information and identify the most effective forums and platforms. Optimal Information Injectors and Motivators: Determine the best individuals for injecting and motivating pro-social engagement and their effective qualities. Barriers and Incentives for Engagement: Explore barriers to engagement and identify incentives or changes to increase engagement among less-engaged individuals.,Descriptive Social Network Study: Assess the relationship between network structure and pro-social engagement, focusing on network density, centrality, homophily, and bridging ties. Qualitative Study: Investigate the dissemination of pro-social engagement information, identifying effective channels, key information injectors, motivators, barriers, and incentives for increasing engagement.,
Kenya 2025-07-04 14:15:43 2028-07-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Laura Nsangi Joan
ID: UNCST-2025-R016715
ValgaNciclovIR for CMV Viraemia in AdvaNced HIV diseAse
REFNo: HS6040ES

The primary objective is to determine if valganciclovir is safe and efficacious in reducing CMV viraemia amongst hospitalised adults with advanced HIV disease and CMV viraemia.
Secondary objectives are to determine the effect of valganciclovir on mortality, to study its pharmacokinetics and explore the immunological response of patients with CMV viraemia before and after treatment with valganciclovir.

Uganda 2025-07-04 14:08:02 2028-07-04 Medical and Health Sciences Clinical Trial Non-degree Award
Luiza CardosodeAndrade
ID: UNCST-2025-R018410
Measuring chlorination in areas with active Evidence Action chlorine delivery interventions
REFNo: SS3948ES

This study aims to assess the take-up of drinking water chlorination under DSW and ILC in Uganda and to compare different measurement methodologies to help improve monitoring protocols. The primary outcome of interest is the total number of people who use water pointers with DSW or ILC for which we can detect chlorine residual in the drinking water. Secondary outcomes explore differences in the methods used to estimate chlorination. In particular, we are interested in comparing chlorination rates measured using two different sampling frames (self-reported water point users and water point users listed) and two different chlorine residual measurement instruments (color discs and colorimeters). The tertiary outcome is the functionality of chlorination devices, which may be connected to low adoption. Finally, additional data will be collected to perform an exploratory analysis on other factors that may influence the adoption of chlorine for water treatment, such as the distance to the nearest water point where chlorine is available and the occurrence of symptoms related to the consumption of contaminated water.
Brazil 2025-07-04 14:02:44 2028-07-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
Maternal Ultrasound Prospective Observational Study for Machine Leaning Model Training
REFNo: HS6020ES

1. Collect ultrasound data from pregnant and non-pregnant individuals presenting at Kawempe national referral hospital. 2. Use the collected data and ultrasound images to train and validate MOBUS algorithms.,
Uganda 2025-07-04 14:00:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID: UNCST-2021-R011663
SEROPREVALENCE OF MARBURG VIRUS INFECTION AND OTHER WHO-PRIORITY PATHOGEN IN THREE (3) COUNTRIES IN AFRICA
REFNo: HS6241ES

Primary objectives 1.To assess previous exposure to Marburg Virus (MARV) Infection in the general population in three (3) African countries, determined by measuring circulating IgG antibodies.
2.To estimate MARV force of infection (FOI) in the three (3) African countries. 3.To develop a platform for the implementation of seroprevalence of WHO priority pathogens in Africa Secondary objectives 1.
To characterize age-specific and gender-specific seroprevalence trends. 2.To determine risk factors associated with prior infection with MARV in the three (3) African countries. 3. To assess host genetic factors including single nucleotide polymorphism (SNP) of candidate genes that could be associated with susceptibility/protection from infection with MARV and other outbreak-worthy pathogens. 4.To estimate the seroprevalence of other WHO priority filovirus pathogens, including EBOV, SUDV, BDBV, TAFV, RAVN, etc. Exploratory objectives 1.To evaluate potential cross-reactivity of MARV IgG with other filoviruses. 2.To investigate neutralizing capacity of human monoclonal antibodies against MARV
Uganda 2025-07-04 13:58:59 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
Paediatric Post-TB home-based Pulmonary Rehabilitation Feasibility Study
REFNo: HS6222ES

Primary objective:
• To explore the feasibility of implementing a 6-week at home pulmonary rehabilitation program in children with diagnosed with PTLD, including measures of participant retention and adherence.

Secondary objectives:
• To evaluate the change in health-related quality of life following the pulmonary rehabilitation intervention.
• To assess the change in exercise capacity following the 6-week pulmonary rehabilitation intervention.
• To explore the experiences and perceptions of children, caregivers, and healthcare providers related to the acceptability and feasibility of the pulmonary rehabilitation program

Uganda 2025-07-04 13:57:06 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tarekegn Abeku Abose
ID: UNCST-2023-R005864
improving early warning and control of mosquito-borne disease outbreaks caused by extreme weather in Uganda
REFNo: HS5162ES

Main Objective
1. The project’s main objective is to strengthen the health system capacity in Uganda for improved early warning and rapid control of mosquito-borne disease outbreaks caused by extreme weather events, focussing on malaria RVF and YF.
Specific Objectives
1. 1. To document past mosquito-borne disease outbreaks in Uganda and analyse their association with extreme weather
2. 2. To develop and validate a risk index and early warning models to forecast the outbreaks
3. 3. To develop a platform that maps risks and generates predictions continuously, where real-time surveillance data feed into, for routine use by disease control programmes
4. 4. To develop an outbreak preparedness and response plan for various risk scenarios
5. 5. To facilitate adoption and use of the system
6. 6. To engage communities in the research activities
UK 2025-07-04 13:55:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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