Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Gertrude Nakigozi
ID: UNCST-2025-R022719
 The Many faces of Trauma and Recovery around the World: Mapping Experiences in Cultural Context (Matrix) Pilot Study
REFNo: HS7621ES

1. Assess the cultural relevance, feasibility and acceptability of the study design and instruments (survey and in-depth interview questionnaire) to inform implementation feasibility in Phase II of the project. 2. Preliminarily explore cross-cultural experiences of traumatic events, including individual psychological and somatic responses to PTEs, their perceived causes, approaches to coping and healing, subjective wellbeing and functioning, and the role of culture, context and identity. 3. Identify cross-cultural conceptualizations and expressions of trauma, including convergences and divergences in traumatic experiences, trauma sequelae, idioms of distress, and cultural scripts, their subjective interpretation and the meaning attributed to these. 4. Investigate culturally-specific healing and coping strategies, including individualistic vs collective approaches.
Uganda 2026-05-28 16:43:56 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
 UCatchUp cost-effectiveness evaluation
REFNo: SS5226ES

Understand the potential to scale up the UCatchUp program,
 Uganda 2026-05-28 16:42:20 2029-05-28 Social Science and Humanities Non-degree Award
Florence Kyoheirwe Muhanguzi
ID: UNCST-2021-R002777
 Climate Resilience Solutions in the West Nile Region of Uganda (CARIS)
REFNo: SS5142ES

The primary objective of CARIS is to investigate the complex interplay of hydrological, ecological, and socioeconomic factors in the West Nile region of Uganda, focusing on the Enyau River catchment within the context of climate change.
Uganda 2026-05-28 16:39:51 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Namulema Edith
ID:
Exploring the feasibility and safety of using the ‘LeVe Neonatal CPAP System’ to assist neonates with signs of respiratory distress at Mengo Hospital
REFNo: HS7747ES

1) Feasibility Objective - To determine the proportion of neonates in whom the LeVe CPAP device can be successfully initiated and maintained for the entire study duration.
2) Safety Objective - To determine the incidence of CPAP-related adverse events occurring within the first 7 days of CPAP therapy.
3) Respiratory Effectiveness Objective - To assess the early respiratory response to CPAP within 2 hours of initiation and for the entire study duration using SpO?, FiO? measures and the Silverman-Andersen respiratory distress score.
4) Prematurity-Related Outcome Objective - To determine the incidence of survival to discharge, bronchopulmonary dysplasia, and retinopathy of prematurity.
5) To explore healthcare workers' perceptions and experiences regarding CPAP training adequacy, their confidence in using neonatal CPAP, and their views on how CPAP implementation influences neonatal respiratory outcomes within their clinical setting

 Uganda 2026-05-28 16:35:26 2029-05-28 Medical and Health Sciences Clinical Trial Non-degree Award
Martin Bakunda
ID: UNCST-2025-R022360
 FINANCIAL LITERACY AND FINANCIAL WELLBEING A MODERATED MEDIATED RELATIONSHIP OF SOCIAL CAPITAL AND FINANCIAL STRESS AMONG MICRO AND SMALL BUSINESS OWNERS IN KAMPALA, UGANDA
REFNo: SS5363ES

I. To examine the effect of Financial Literacy on Financial Wellbeing II. To determine the effect of Financial Stress on Financial Wellbeing III. To assess the effect of Social Capital on Financial Wellbeing IV. To examine the effect of Financial Literacy on Financial Stress V. To examine the mediation effect of Financial Stress on the relationship between Financial Literacy and Financial wellbeing VI. To examine the moderating effect of social capital on the relationship between financial literacy and financial stress VII. To assess the moderating effect of social capital on relationship between financial literacy and financial wellbeing VIII. To examine the moderating effect of social capital on the relationship between financial stress and financial wellbeing IX. To analyze the moderation effect of social capital on the indirect relationship between financial literacy and financial wellbeing through financial stress
Uganda 2026-05-28 16:33:41 2029-05-28 Social Science and Humanities Degree Award
Elly Atuhumuza
ID: UNCST-2024-R002706
 Evaluating the Active Ingredients and Dose Response Effects of Group Interpersonal Psycho-therapy Components on Depression
REFNo: HS7468ES

1. To determine the comparative effectiveness of each core IPT-G component (psychoeducation, peer support, and problem-solving skills) in reducing depression symptoms (as measured by the PHQ-9) from baseline to post treatment, when delivered as a single session. 2. To determine feasibility and acceptability of each individual arm. 3. To assess the effect of session intensity (duration) on the efficacy of each core component by comparing outcomes across low, medium, and high intensity doses for a single session. 4. To evaluate the effect of treatment frequency (number of sessions) on the efficacy of each core component by comparing outcomes from a single session, 2, 4, and 6 sessions with enhanced treatment as usual. duration. 5. To identify interaction effects between the type of active ingredient, session intensity, and treatment frequency to determine if certain components benefit more from increased duration, increased number of sessions, or a specific combination of both. 6. To develop an optimized therapy model by synthesizing the findings to propose a stream- lined protocol that specifies the most potent components and their minimal effective dosage for reducing depression symptoms in low resource settings.
Uganda 2026-05-28 16:30:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Henry Cust
ID: UNCST-2025-R021803
 Empirical Insights into the Real Cost of PEPFAR and USAID HIV Funding Cuts in sub-Saharan Africa
REFNo: SS4802ES

1) To assess the impact of the US budget cuts on HIV service provision and health outcomes in sub-Saharan Africa. 2) To assess the reallocation of resources through the change in relative service provision priorities following the US budget cuts.
 UK 2026-05-28 16:09:44 2029-05-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ronald Mbago
ID: UNCST-2025-R018089
 MANAGEMENT COMPETENCIES, WORK ENGAGEMENT AND SERVICE DELIVERY IN PRIVATE UNIVERSITIES OFFERING OPEN AND DISTANCE LEARNING IN KAMPALA METROPOLITAN AREA, UGANDA
REFNo: SS4373ES

a) To examine the effect of strategic thinking on service delivery in private universities offering ODL in the Kampala Metropolitan Area, Uganda.
b) To evaluate the effect of flexibility on service delivery in private universities offering ODL in the Kampala Metropolitan Area, Uganda.
c) To examine the effect of collaboration on service delivery in private universities offering ODL in the Kampala Metropolitan Area, Uganda.
d) To evaluate the effect of vigor on service delivery in private universities offering ODL in the Kampala Metropolitan Area, Uganda.
e) To examine the effect of dedication on service delivery in private universities offering ODL in the Kampala Metropolitan Area, Uganda.
f) To assess the effect of absorption on service delivery in private universities offering ODL in the Kampala Metropolitan Area, Uganda.
g) To examine overall the effect of management competencies, work engagement on service delivery in open and distance learning in private universities in Kampala Metropolitan Area, Uganda.


 Uganda 2026-05-28 16:02:29 2029-05-28 Social Science and Humanities Non-Clinical Trial Degree Award
FRANCIS  AMAYOA ANYAKA
ID: UNCST-2024-R003877
 INTEGRATING ENVIRONMENTAL SUSTAINABILITY INTO RESEARCH ETHICS REVIEW IN UGANDA: PERSPECTIVES OF RESEARCH ETHICS COMMITTEE MEMBERS.
REFNo: HS7784ES

General Objective To assess the awareness, attitudes, and practices of RECs regarding environmental sustainability, and to identify practical strategies for enhancing its integration into research ethics review. Specific Objectives 1. To assess awareness among REC members regarding environmental sustainability in research. 2. To examine the attitudes and perceptions of REC members toward incorporating environmental sustainability into ethics review processes. 3. To assess current practices for integration of environmental considerations into REC ethics review processes. 4. To identify the barriers and facilitators that influence the integration of environmental sustainability into research ethics review by RECs. 5. To propose strategies for strengthening ethical oversight systems to effectively incorporate environmental sustainability into research governance.
Uganda 2026-05-28 15:58:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alex Saturday
ID: UNCST-2023-R007459
 Effect of Land Use on Water Quality and Biotic Assemblages of Lake Nyabihoko, Western Uganda
REFNo: NS1120ES

i) To assess LULC change patterns from 1992 to 2022 (i.e., 1992, 2002, 2012, and 2022) in the Lake Nyabihoko sub-catchment.
ii) To investigate the spatial and seasonal variability in the physicochemical (i.e., turbidity, temp, DO, EC, pH, TDS, TP, TN, NH4-N, and NO3-N) parameters of water in Lake Nyabihoko.
iii) To investigate spatial and seasonal variability in macroinvertebrate composition, abundance, and diversity in the study area
iv) To investigate phytoplankton composition, abundance, diversity and biomass between wet and dry seasons and among the study stations.

 Uganda 2026-05-28 15:48:35 2029-05-28 Natural Sciences Non-Clinical Trial Degree Award
Dan Ngabirano
ID: UNCST-2025-R021195
 Beyond Legal and other Formal Approaches to the Grand Corruption Problem in Uganda: The Role of Indigenous African Customary Laws, Norms and Institutions
REFNo: SS4691ES

a) To study and document the strength and limitations of relying on legal and other formal approaches to grand corruption in Uganda. b) To interrogate the efficacy of customary laws, norms and institutions in the fight against grand corruption while relying on case studies from Buganda, Bunyoro, Bugisu, Acholi, Kigezi Tswana and Asante societies c)To inquire into the practicability of relying on customary laws, norms and institutions in the fight against corruption in Uganda and whether these should exist as alternatives or rather compliment current legal and formal approaches.
Uganda 2026-05-28 15:46:29 2029-05-28 Social Science and Humanities Non-Clinical Trial Degree Award
Opar BernardToliva
ID: UNCST-2026-R023349
 ASSESSING THE BURDEN AND RESEARCH CAPACITY ON SNAKEBITE ENVENOMING IN NORTHERN UGANDA
REFNo: HS7038ES

To assess the hospital incidence, clinical management practices, and research capacity for snakebite envenoming in Uganda, with the aim of identifying potential clinical trial sites for an upcoming antivenom clinical trial.
 Uganda 2026-05-28 15:42:48 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOSHUA KIPTOO
ID: UNCST-2025-R021984
 Use of Physiologically Based Pharmacokinetic (PBPK) Modelling Approach to Predict Infant Exposure to Bedaquiline, Lamivudine, and Lumefantrine Via Breastmilk
REFNo: HS7748ES

General Objective: To determine infant plasma exposure to Lamivudine, Lumefantrine, and Bedaquiline via breast milk change over the first year of life (0-12 months) Specific objectives 1. To develop a PBPK model for the prediction of infant plasma exposure to Bedaquiline, Lamivudine, and Lumefantrine via breast milk 2. To determine the variability in infant plasma exposure to Bedaquiline, Lamivudine, and Lumefantrine via breast milk during the first year of life (0-12 months)
Uganda 2026-05-28 15:39:46 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
 Field Performance Verification of the XL1000e Automated Blood Coagulation Analyzer at Health facilities in Uganda: A Method Verification and Comparative Evaluation Study
REFNo: HS7524ES

To determine the operational characteristics and user satisfaction associated with the XL1000e. To conduct a method comparison between the XL1000e and the Sysmex CA-660/CS510 analyzer as a reference using patient samples. To evaluate the analytical performance (precision, accuracy, carryover, linearity) of the XL1000e in measuring Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Thrombin Time (TT), Fibrinogen (FIB), and D-dimer.
 Uganda 2026-05-28 15:38:43 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Otim
ID: UNCST-2024-R016522
 Item Bank Development for Paediatric Malignancies: A Tool for Quality-of-Life Evaluation and Prognostic Prediction in Northern Ugandan Children.
REFNo: HS7281ES

Primary Objective: Develop an item bank for pain, nausea, loss of appetite, physical functioning, cognitive impairment, sleep quality and fatigue among children with cancer.
Secondary Objectives: (i)Correlate tumour size, serum LDH levels and patient quality of life among children with cancer.
(ii) Explore using self-reported measures to predict prognosis in children with cancer during chemotherapy.
Uganda 2026-05-28 15:35:44 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Haliima Nalugo
ID: UNCST-2025-R020120
 Seroprevalence and Molecular Detection of Brucella Species in Archived Wildlife Samples at Queen Elizabeth National Park (QENP), Uganda
REFNo: HS7529ES

To estimate the seroprevalence and detect Brucella species among selected wildlife species in Queen Elizabeth National Park
 Uganda 2026-05-28 15:32:04 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Oscass Jimmy  Ruva
ID:
Moral Beliefs, Clinical Discretion, and Behaviour Change Interventions: Understanding Provider-Driven Rationing of Post-Abortion Care in Uganda’s Restrictive and Fragile Health System.
REFNo: HS7425ES


To describe providers’ Moral Beliefs and Clinical Discretion shape the rationing of post-abortion care in Uganda’s Restrictive and Fragile Health System, and how trainings and behaviour change interventions influence these practices
 Uganda 2026-05-28 15:30:30 2029-05-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Palliative care needs of children and young people living with serious illnesses and their families in Uganda
REFNo: SS5166ES

How do the palliative care needs of children and young people living with serious illnesses change over time? ,What are the palliative care needs of children and young people living with serious illnesses in Uganda? ,
 Uganda 2026-05-28 15:29:15 2029-05-28 Social Science and Humanities Non-degree Award
Lorna Atikoro
ID: UNCST-2024-R002527
 REDUCING THE BURDEN OF METHICILLIN RESISTANT Staphylococcus aureus (MRSA) INFECTIONS IN UGANDAN PATIENTS RECEIVING HAEMODIALYSIS
REFNo: HS7485ES

1. To estimate the prevalence of MRSA carriage among patients receiving chronic haemodialysis at Kiruddu National Referral Hospital.
2. To determine the factors associated with MRSA carriage among patients receiving chronic haemodialysis at Kiruddu National Referral Hospital.
3. To determine the success rate of mupirocin ointment in eradicating nasal carriage of MRSA among patients receiving chronic haemodialysis at Kiruddu National Referral Hospital

 Uganda 2026-05-28 15:23:03 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank Kaharuza Mugisha
ID: UNCST-2025-R022389
 ASSESSING THE CONTRIBUTION OF THE SAFE BIRTH AFRICA (SBA) PROJECT IN UGANDA: AN IMPLEMENTATION RESEARCH STUDY ON HEAT-STABLE CARBETOCIN AND TRANEXAMIC ACID FOR POSTPARTUM HAEMORRHAGE PREVENTION AND TREATMENT
REFNo: HS7496ES

The General objective is to generate evidence on the implementation effectiveness and contribution of the Safe Birth Africa project in improving equitable access to and utilization of HSC and TXA for postpartum haemorrhage prevention and treatment in Busoga region and Kampala, Uganda. The specific objectives are 1. To assess the implementation fidelity of SBA interventions (HSC and TXA) across different health facility levels in Busoga region and Kampala. 2. To explore the facilitators and barriers to implementation of the SBA interventions across the pilot sites and regions. 3. To understand health worker experience in the use of HSC for prevention and TXA for treatment of PPH.
Uganda 2026-05-28 15:11:40 2029-05-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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