Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Edward Bbaale
ID: UNCST-2025-R017376
Improving Bill Payment for Water and Sanitation Services in Uganda
REFNo: SS3693ES

Understand the magnitude and scope of arrears among NWSC customers (secondary billing records) Design and test an intervention to improve customer bill payment among NWSC residential customers (randomized controltrial of staff incentives)
Assess customer perceptions of a fair price for water service (household survey with randomized information treatment) To investigate the role of information provision in improving the payments for water and sanitation services
Uganda 2025-04-11 16:52:44 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Begumana Daniel
ID: UNCST-2024-R003195
INCIDENCE OF AND RISK FACTORS OF COMPLICATIONS OF TREATMENT FOR PREMALIGNANT CERVICAL LESIONS AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5782ES

To determine the incidence of and describe the nature of early complications of treatment for premalignant cervical lesions at Mbarara Regional Referral Hospital.

To determine the risk factors associated with early complications of treatment for premalignant cervical lesions at Mbarara Regional Referral Hospital.


Uganda 2025-04-11 16:50:45 2028-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
John Okeya Bonaventure
ID: UNCST-2024-R016505
Enhanced Shared Leadership in promoting Instructor Effectiveness in Technical Institutes in Uganda: Case of Eastern Uganda
REFNo: SS3708ES

1. To establish how shared leadership is promoted in Technical Institutes in Uganda. ,3. To explore Enhanced shared leadership practices that promote instructor effectiveness in Technical Institutes in Uganda.,2. To explore Instructors’ experience of shared leadership in Technical Institutes in Uganda.,1. To establish the promotion of shared leadership in Technical Institutes in Uganda. ,
Uganda 2025-04-11 16:49:15 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS)
REFNo: HS5498ES

•Aim 1: Refine SkinScan3D Technology and Usage Protocols for Routine KS Imaging:
•Aim 2: Compare Reproducibility and Accuracy of KS Lesion Size Measurements Between SkinScan3D and Current Standard of Care Measurement.
•Aim 3: Validate and Optimize SkinScan3D Clinical Workflow in Real-World Settings.

Uganda 2025-04-11 16:47:49 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phiona Bukirwa
ID: UNCST-2022-R009880
Cancer Registration in Kyadondo County, Uganda
REFNo: HS5693ES

1. To describe the cancer incidence trends in Kyadondo County from the year 2017 (last year of complete registration) to date. 2. To determine the age-specific incidence rates and crude incidence rates per 100,000 of the population for the different cancers found amongst the population of Kyadondo County. 3. To determine the proportion of cancer patients who get treatment for their cancer. 4. To determine cancer survival for the registered cases.
Uganda 2025-04-11 16:44:55 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Henry Ddungu
ID: UNCST-2019-R000966
Evaluating the Effectiveness of a Video-Based Educational Initiative for Cancer Patients and Caregivers in Uganda
REFNo: HS5791ES

Our study aims to test the acceptability and efficacy of a video education tool for improving patient and caregiver knowledge and understanding regarding cancer diagnosis and treatment. ,
Uganda 2025-04-11 16:44:08 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HARRIET KUSIIMA
ID: UNCST-2023-R006553
Barriers and facilitators to optimal treatment coverage of mass drug administration for schistosomiasis among adults in Mayuge District, Uganda
REFNo: HS5732ES

(i) To assess the perceptions of programme implementers regarding the implementation of MDA for schistosomiasis among adults in Mayuge district, Uganda.

(ii) To explore the barriers to optimal treatment coverage of MDA for schistosomiasis among adults in Mayuge district, Uganda.

(iii) To explore the facilitators to optimal treatment coverage of MDA for schistosomiasis among adults in Mayuge district, Uganda.

Uganda 2025-04-11 16:41:06 2028-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
Proof-of- concept: Understanding Non-Tuberculous Mycobacteria Diversity, Evolution, Epidemiology and Pathogenicity in Tuberculosis-High Burden African Contexts (DEEP-NTM): Uganda
REFNo: HS5734ES

Objective 1 (O1) To describe the species and intra-species level diversity of NTM within each geographical area through phylogenomic studies.
Objective 2 (O2) To understand the phylogeography of non-tuberculous mycobacteria in sUganda.
Objective 3 (O3) To assess the significance of NTM isolates and their relation to NTM-PD in different populations.
Objective 4 (O4) To use results as a proof-of-concept to design a prospective multi-centre study to:
i) investigate sub-regional geographical variations
ii) to distinguish variants associated with colonisation and NTM-PD
iii) to identify risk factors, potential routes of acquisition and transmission and clinical outcomes of NTM-PD.
Uganda 2025-04-11 16:38:31 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANNAH ATUHAIRE
ID: UNCST-2021-R011702
MEDIATING EFFECT OF INCLUSIVE STRATEGIES ON THE RELATIONSHIP BETWEEN STAKEHOLDER COLLABORATION AND EDUCATIONAL INCLUSION OF CHILDREN IN STREET SITUATIONS IN UGANDA
REFNo: SS3751ES

i. To examine the effect of stakeholder collaboration on educational inclusion of children in street situations under the condition of controlling for covariates in Kampala district, Uganda.
ii. To assess the effect of stakeholder collaboration on inclusive strategies for education of children in street situations in Kampala district, central Uganda.
iii. To assess the effect of inclusive strategies on educational inclusion of children in street situations in Kampala district, Uganda.
iv. To examine the mediating effect of inclusive strategies on the relationship between stakeholder collaboration and educational inclusion of children in street situations in Kampala district, Uganda.
v. To explore the perceptions of stakeholders towards inclusive strategies for enhancing stakeholder collaboration for educational inclusion of children in street situations in Kampala district, Uganda

Uganda 2025-04-11 16:37:44 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
Keya Khandaker
ID: UNCST-2024-R016173
State of the Worlds Girls 2025 - Child, Early and Forced Marriages and Unions
REFNo: SS3753ES

Justification:
Despite large-scale policy action and legislative reform towards addressing child marriage, the practice remains highly prevalent. There is a growing urgency in the need to spotlight efforts to end CEFMU - while the global prevalence is decreasing, it is doing so far too slowly. ICRW and Plan International research suggests child marriage persists due to the interplay of gender norms, poverty, as well as wider scale issues around weak enforcement of legislation, poor economic prospects for girls, and natural and humanitarian disasters. The persistence of child marriage is an outcome of global level crises - referred to by UNICEF as a ‘polycrisis’ – that are indicative of the global rollback on girls’ rights. There is a clear need for further evidence on the lives and contexts of the girls who are often ‘hard-to-reach’: by engaging with already married girls / girls in unions, this research can establish how we can effectively support these girls who have been missed by current child marriage interventions. Key to the research is the ability to adapt the findings to make clear, evidence driven recommendations for action that will be relevant for Plan offices focused on addressing CEFMU at the community through to the global and regional level.
Objectives:
1. 1. What are married girls’ / girls in unions’ everyday experiences across livelihoods and income, health, education, household decision-making, and agency?
2. 2. In what ways does existing legislation, service provision and policy on CEFMU support married girls? And how are these measures implemented to be inclusive of marginalized married girls?
3. 3. What support do girls in marriages / unions need to promote and safeguard their rights?
UK 2025-04-11 16:35:51 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
brian nyasulu
ID: UNCST-2024-R002157
MALE INVOLVEMENT IN CONTRACEPTIVE DECISION MAKING AND SUPPORT FOR LONG-ACTING REVERSIBLE METHODS AMONG COUPLES IN KAMPALA, UGANDA
REFNo: HS5778ES

1.To assess the extent of male involvement in decision-making about long-acting reversible contraceptives (LARC) among couples in Kampala Uganda. 2.To identify key factors influencing male involvement in long-acting reversible contraceptives (LARC) use and decision-making in Kampala Uganda. 3.To determine barriers affecting male involvement in long-acting reversible contraceptives (LARC) use decision-making in Kampala Uganda. 4.To evaluate the role of healthcare providers in promoting male involvement in long-acting reversible contraceptives (LARC) use methods in Kampala Uganda.
Malawi 2025-04-11 16:30:28 2028-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Khamisi Musanje
ID: UNCST-2021-R012863
Behavioural Problems Associated with Internet Usage Among Ugandan Children
REFNo: SS3757ES

1. To identify the content children aged 11-14 years access on the Internet in Uganda.

2. To determine the frequency and duration of internet use among children aged 11-14 years in Kampala, Uganda.

3. To investigate the behavioural problems linked to internet usage among children aged 11-14 years in Kampala, Uganda.

4. To examine the relationship between internet usage and behavioural problems among children aged 11-14 years in Kampala

5. To investigate the moderating effect of social factors (age of internet initiation, gender, class in school, type of school and
current age) on the relationship between internet usage and behavioural problems.
Uganda 2025-04-11 16:28:27 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
ronald omolo ouma
ID: UNCST-2023-R007754
Dementia Detection from a Generated Runyankole-Rukiga Speech-Data set with Speech Analysis and Machine Learning Techniques
REFNo: HS5749ES

1. To generate a dementia speech dataset for Runyankole-Rukiga in southwestern Uganda
2. To build and pilot test a speech-based machine learning algorithm that distinguishes a person with dementia from one without dementia among Runyankole-Rukiga speakers within Southwestern Uganda
Uganda 2025-04-11 16:25:55 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arinaitwe Juliet
ID: UNCST-2024-R016009
PERCEPTION OF TEACHERS ON ADMINISTRATIVE SKILLS OF HEADTEACHERS AND SCHOOL CLIMATE IN SECONDARY SCHOOLS
REFNo: SS3754ES

To find out the relationship between the administrative skills of headteachers and school climate as perceived by secondary school teachers.

To find out the difference in the perceptions of secondary school teachers on the administrative skills of headteachers and school climate with regard to; Age, Gender, Educational qualifications, Teaching experience, Years spent in the same school, Type of school, and Locality of the school.

To determine which specific administrative skill of the headteacher has a stronger influence on the school climate as perceived by secondary school teachers.

To find out the impact of the administrative skills of headteachers on teachers’ professional development and work environment.

Uganda 2025-04-11 16:24:58 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
ANNA TURUMANYA KALUMUNA
ID: UNCST-2023-R006534
ACCEPTABILITY OF AMBULATORY SURGERY WITH AN INNOVATIVE RECOVERY AT HOME PROGRAM, AND ITS ASSOCIATED FACTORS AMONG SELECTED HEALTH SYSTEM STAKEHOLDERS IN UGANDA
REFNo: HS5528ES

1. To determine the level of acceptability of ambulatory surgery with an innovative at
recovery at home program among selected health system stakeholders in Uganda
2. To analyze the factors associated with the acceptability of ambulatory surgery with an
innovative at recovery at home program, among selected health system stakeholders in
Uganda
3. To establish the intrapersonal factors associated with the acceptability of ambulatory
surgery with an innovative at recovery at home program, among selected health system
stakeholders in Uganda
4. To assess the institutional factors associated with the acceptability of ambulatory surgery
with an innovative at recovery at home program, among selected health system
stakeholders in Uganda
Uganda 2025-04-11 16:23:23 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Mark Kazibwe
ID: UNCST-2024-R002834
PREVALENCE AND FACTORS ASSOCIATED WITH POSTPARTUM USE OF LONG-ACTING REVERSIBLE CONTRACEPTIVES AMONG WOMEN 15- 45 YEARS, IN BUTAMBALA DISTRICT, SOUTH CENTRAL UGANDA
REFNo: HS5563ES

General objectives.
To determine the prevalence and factors associated with post-partum use of long-acting reversible contraception within 12 months after birth, among women aged 15-45 years in Butambala district.
Specific objectives.
1. To ascertain the prevalence of postpartum use of long-acting reversible contraception within the first 12 months after childbirth among women aged 15-45 years in Butambala district.
2. To determine socio-demographic factors associated with postpartum use of long-acting reversible contraception within the first 12 months after childbirth among women aged 15-45 years in Butambala district.
3. To determine obstetric factors associated with postpartum use of long-acting reversible contraception within the first 12 months after childbirth among women aged 15-45 years in Butambala district.

Uganda 2025-04-11 16:22:09 2028-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
An Open-label, Single-arm Study to Provide Continued Access to Study Drug to Participants Who Have Completed Pediatric Clinical Studies Involving Gilead HIV Treatments.
REFNo: HS5804ES

The primary objective of this trial is to provide continued access to the study medication received in the parent protocol or switch to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF; coformulated; Biktarvy®) for participants who completed a Gilead parent study evaluating medications for HIV treatment.
Uganda 2025-04-11 16:20:58 2028-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
STEPHEN DUSENGIMANA
ID: UNCST-2025-R017043
COST MANAGEMENT PRACTICES AND FINANCIAL PERFORMANCE OF PRIVATE SECONDARY SCHOOLS IN UGANDA: ACASE STUDY OF KAGADI DISTRICT, WESTERN REGION
REFNo: SS3722ES

1. To assess the contribution of budgeting in terms of Timeliness, Variance Analysis, transparency on financial performance of Private Secondary Schools in Kagadi District, western region, Uganda
2. To examine the effect of Financial reporting in terms of completeness, compliance and consistency on financial performance of Private Secondary Schools in Kagadi District, western region, Uganda
3. To analyze the level of cost control in terms of cost reduction and cost variance on financial performance of Private secondary schools Kagadi District, western region, Uganda
4. To investigate the moderating effect on the relationship between cost management practices and financial performance of private secondary schools in Kagadi, western region, Uganda

Uganda 2025-04-11 16:07:56 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
TESTING MULTI-LEVEL SCALE-UP STRATEGIES TO IMPLEMENT A SCHOOL-BASED POPULATION APPROACH OF MENTAL HEALTH PREVENTIVE INTERVENTION: UGANDA
REFNo: HS5647ES

General Objective
The overall goal of this study is to address vertical and horizontal scale-up implementation framework gaps in Uganda. This study will test new recommended vertical scale-up and sustainability implementation strategies and study impact and underlying mechanisms when the new scale-up model is applied.
This research will guide the development of evidence-informed theoretical frameworks and processes to effectively institutionalize EBIs in LMICs such as Uganda. To achieve this goal, we will carry out 4 sequential steps (4 aims).
Specific Objectives
1.
To establish a cross-level partnership and strengthen stakeholders/leaders’ advocacy capacity to make evidence-based informed children’s mental health policy and practice decisions and to facilitate the EBI institutionalization through the educations system illustrated in figure 1.
2.
To develop implementation Protocols in collaboration with cross level partners (established in Aim 1) based on a new multilevel train-the-trainer scale-up framework to support the EBI/PD scale-up.
10
3.
Implement the new Protocols for scale-up and test the relative value of additional implementation supports intended to sustain teacher EBI practices through a Hybrid III cRCT.
4.
To explore underlying scale-up and sustainability implementation mechanisms.
Uganda 2025-04-11 16:03:54 2028-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
Jacklyn Arinaitwe Makaaru
ID: UNCST-2024-R015354
Impact Evaluation of Childcare Services for Kampala Market Women Study
REFNo: SS3696ES

Primary objectives:
a. To assess the labour market effects (labour force participation and productivity) of gaining access to childcare services by women working in markets in Kampala.
b. To assess the effects of gaining access to childcare services on the well-being of women working in markets in Kampala.
c. To assess the effects of gaining access to childcare services on the well-being of children of women working in markets in Kampala.

Secondary objective:
d. To assess important dimensions of heterogeneity, related to accessibility, wealth levels, women’s agency, and child’s age.
e. To explore secondary outcomes of access to childcare services by women working in markets in Kampala including spillover effects on other household members, and changes in mobility.


Uganda 2025-04-11 16:00:39 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
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