Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Peter Olupot-Olupot
ID:
Coronavirus Disease 2019 Open Cohort (COC) Study
REFNo: HS611ES

The specific objectives:
1. Through a cross sectional survey describe risk factors and enlist study participants for the cohort study.
2. To characterize the clinical spectrum of COVID-19.
3. To refine case definitions of COVID-19 using data from different population groups.
4. To explore in detail, the epidemiology of COVID-19.
5. To document outcomes associated with COVID-19 in various age groups, populations and concomitant conditions.
6. To generate data to inform clinical research on COVID-19.
7. To generate population specific data for evidence based public health education as a control measure.
8. Provide a decision tree that has automated feedback that has standard of care including quarantine, call help-line, seek medical attention and avoid spread of the disease.

Uganda 2020-04-03 2023-04-03 Medical and Health Sciences Non-degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
Acceptability, effect and cost of mobile-health on art adherence among youths: a mixed methods sequential study in Kiryandongo
REFNo: HS576ES

General objective: To assess the acceptability, effect and cost of the Call For Life Uganda mHealth tool on ART adherence among youth initiating ART at Kiryandongo Hospital.

Specific objectives:
Objective 1a: To assess barriers, enablers of ART adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 1b: To assess acceptability of mHealth for HIV adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 2: To assess effect of the CFLU mHealth tool on ART adherence among youths initiating ART at 6 and 12 months.
Objective 3: To evaluate the cost of the CFLU mHealth adherence tool in comparison to Standard of Care.

Uganda 2020-03-28 2023-03-28 Medical and Health Sciences Degree Award
Anthony Matovu
ID:
G - Therapy: Classical Mechanical Resonance Tool For HIV Cure
REFNo: SIR26ES

Main Objective
To design and implement an effective, safe, “isolate – and – kill” Classical Mechanical resonance tool for HIV – riddance from HIV – positive patients.

Specific Objectives
a) To outline a velocity, frequency and wavelength generating system based on scalable vibratory/circulatory dynamics pertinent with the vibratory characteristics of the HIV particles (H – 1 atom system is earmarked).
b) To identify the HIV virus by morphology (physical structure) differentiation using light optical nanoscopy – observation procedures (use flue virus for comparison).
c) To characterize the projected mechanical resonance – based fight between HIV and human defense system cells (realizable by articulating and relating factors implicated).
d) To design and implement a counter resonance tool against HIV’s own mechanical resonance combat weapon against human defense cells (achievable through determining rupture-prone resonant frequency-amplitude factors leading to an effective, safe body- penetrative capacity; as well as the functional body/specimen exposure period).

Uganda 2020-03-20 2023-03-20 Engineering and Technology Degree Award
Doreen Nakku
ID:
Assessment of knowledge and attitudes towards hearing loss and community utilisation of hearing screening services at a Health Centre IV in Mbarara District
REFNo: HS549ES

1. To assess knowledge on hearing loss and attitudes towards hearing loss of communities served by Bwizibwera HC IVs in Mbarara District
2. To assess the utilisation of hearing screening services at Bwizibwera HC IVs in Mbarara District.
Uganda 2020-03-20 2023-03-20 Medical and Health Sciences Non-degree Award
KAHUNZIRE EVANGELIST
ID:
Evaluation of parental involvement on primary pupils educational academic performance in public day primary schools of Ndorwa County,Kabale District-Uganda.
REFNo: SS426ES

To establish the relationship between parental involvement on primary pupils educational academic performance in selected public day primary schools of Ndorwa County,Kabale District-Uganda.
To examine the utilization of educational domains on primary pupils'educational academic performance in selected public day primary schools of Ndorwa County ,Kabale District-Uganda.
To formulate a parenting involvement model that enhances primary pupils'educational academic performance in selected public day primary schools of Ndorwa Ounty,Kabale District-Uganda.
Uganda 2020-03-20 2023-03-20 Social Science and Humanities Degree Award
Paddy Tukamuhebwa Mutungi
ID: UNCST-2020-R014201
Barriers and facilitators of investigation coverage among index tuberculosis case contacts in rural Mbarara district, Uganda.
REFNo: HS569ES

1. To identify the barriers of TB contact investigation coverage among contacts of TB index clients in three rural primary health facilities in Mbarara district in Uganda. 2. To identify the facilitators of TB contact investigation coverage among contacts of TB index clients in three rural primary health facilities in Mbarara district, Uganda.
Uganda 2020-03-20 2023-03-20 Medical and Health Sciences Degree Award
Charles Batte
ID: UNCST-2021-R013587
Hypertension and cardiovascular diseases comorbidities among people living with HIV: A health outcomes and cost study.
REFNo: HS581ES

• To determine and compare Health Related Quality of Life (HRQoL) of People living with HIV (PLWH) with or without hypertension and/or CVD comorbidities that have been on ART for more than 10 years in Uganda using both generic and disease specific HRQoL tools.
• To determine and compare health care utilization costs of patients with HIV & HTN/CVD and those with HIV alone.

Uganda 2020-03-20 2023-03-20 Medical and Health Sciences Non-degree Award
Peter MUSINGUZI
ID:
Social Enterprises and sustainable rural development: performance and impacts on beneficiaries’ livelihood
REFNo: SS434ES

General objective To guide the design and operation of Social Enterprises in rural development Specific objectives 1.To analyse what CSFs determine the performance of SEs 2.To understand how the presence and influence of CSFs in SEs varies across contexts. 3.To determine and describe how SE management and performance influence impact on stakeholders.
Uganda 2020-03-20 2023-03-20 Social Science and Humanities Degree Award
Obbo Aggrey
ID:
Algorithms for detection and management people crowds using wireless sensor networks
REFNo: SIR31ES

Design develop and analyze algorithms for people crowds detection and management using wireless sensor networks.
Uganda 2020-03-20 2023-03-20 Engineering and Technology Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
Influencing Sepsis policy in Uganda
REFNo: HS517ES

The main objective of this study is to generate evidence on how researchers’ stakeholder engagement influences Uganda’s health policy agenda. The study will be guided by the following specific objectives.
1. Assess changes in Uganda’s health policy agenda around sepsis as a result of ARCS policy stakeholder engagement activities.
2. Reflectively review the process stakeholder engagement strategies (Informing and translating, Linking, Matchmaking, and Capacity strengthening) designed to influence key stakeholders to recognise sepsis as a priority health issue and put it on Uganda’s policy agenda.

Uganda 2020-03-18 2023-03-18 Medical and Health Sciences Non-degree Award
Catherine Carlson
ID: UNCST-2023-R007222
Promoting Resilience for Survivors of Trafficking: Evaluating a Yoga-Based Approach in Kampala, Uganda
REFNo: SS420ES

Healing and Resilience through Yoga (Hart Yoga) is a trauma-informed yoga program to support survivors of human trafficking in Uganda with psycho-social recovery. The
proposed study will evaluate Hart Yoga’s feasibility, acceptability and impact with women and adolescent girls residing in Willow International’s (https://www.willowinternational.org/) shelters for survivors of human trafficking in Kampala, Uganda. This study will advance the limited field of health and mental health research with survivors of human trafficking and provide pilot data for publication and the development of a subsequent effectiveness trial. The methodology will address two primary objectives:

• Objective 1: To determine Hart Yoga’s feasibility and acceptability among participants and successful delivery within a residential shelter setting.
• Objective 2: To assess physical, psychological and social outcomes among program participants using qualitative and quantitative methods.

USA 2020-03-18 2023-03-18 Social Science and Humanities Non-degree Award
Alex  Muganzi Muganga
ID: UNCST-2019-R000710
Project Evaluation Protocol for West-West Nile Region mechanism.
REFNo: HS554ES

Evaluation Objective 1: To evaluate the targeted HTS models to improve earlier identification of HIV positive and negative individuals, and Linkage of PLHIV in community and facility sites in scale up districts and linkage and promotion of HIV prevention among HIV negative individuals.

Evaluation Objective 2: To evaluate innovative approaches that increase adherence, ART retention and viral load suppression among adult and pediatric HIV clients.

Evaluation objective 3: To determine if there is improved identification of TB infected individuals., effective scale up of comprehensive TB/HIV services at individual sites site, and progress towards reduction of TB burden among HIV/TB co-infected clients within the CDC supported regions and districts.

Evaluation objective 4. To evaluate innovative PMTCT & HEI approaches that increase identification of HIV positive and syphilis infected pregnant & breastfeeding women (PBFW), enhance immediate ART uptake, adherence and retention, viral load suppression and syphilis treatment among PBFW, reduce MTCT rates of HIV & Syphilis and ensure documentation of 18 month final outcome status for all HIV Exposed infants.

Evaluation objective 5: To evaluate innovative interventions that are designed to improve data quality and data utilization for program evidence-based decision making at facility and district level.

Evaluation objective 6 : To determine if there was increase access of comprehensive OVC services .

Evaluation objective 7: To determine if the strengthening of the existing laboratory network and its quality management systems increased the ART initiation and ART monitoring at facility and district level.

Evaluation Objective 8: To determine if the relationship between district level performance reviews and HR performance had an effect on district performance including access, coverage, retention and loss to follow up.
Evaluation objective 9: To determine if Kampala region mechanism approaches resulted in increased coverage with voluntary medical male circumcision.



Uganda 2020-03-18 2023-03-18 Medical and Health Sciences Non-degree Award
Noah Sendawula
ID:
Youth Livelihood Programme & Empowerment in Wakiso District
REFNo: SS430ES

Main Objective: To assess the effectiveness of Youth Livelihood Programme on Youth Empowerment in Wakiso District.
Specific:
i-To investigate the extent to which YLP has been able to provide vocational skills for youth self-employment in Wakiso District
ii- To analyse the extent to which YLP financial support has enabled youth establish income generation activities in Wakiso district
iii- To examine the extent to which YLP has been able to increase levels of entrepreneurship among youth in Wakiso District.
iv- To extablish the extent to which knowledge & information has been provided for positive mindset change among youth in Wakiso district
Uganda 2020-03-18 2023-03-18 Social Science and Humanities Degree Award
Peter Byansi Kayiira
ID:
Leadership and Management Practices that Support Accountability for Results in Health Support Organizations in Uganda
REFNo: HS585ES

Inquire into the management and leadership practices that health leaders in Uganda’s public and nonprofit health support organizations use and have found effective in nurturing accountability for the achievement of results that matter most to employees, the organization, customers, and donors, hereinafter referred to as key stakeholders
Uganda 2020-03-18 2023-03-18 Medical and Health Sciences Degree Award
Robert Kairania
ID:
Performance of the Asanteâ„¢ HIV-1 Rapid Recencyâ„¢ Assay in recent HIV infections detection and incidence estimation in a Ugandan setting using the Rakai Community Cohort Study
REFNo: HS534ES

Main aim: To determine the performance of the Asanté™ HIV-1 Rapid Recency™ assay in identification of HIV-1 recent infections and incidence estimation in a Ugandan setting with A and D predominant subtypes.

Specific aims
I. To evaluate the diagnostic performance of the Asanté™ HIV-1 Rapid Recency™ assay in identification of recent infections in a setting with A and D predominant subtypes.
II. To establish the false recency rate (FRR) of the Asanté™ HIV-1 Rapid Recency™ assay.
III. To determine factors associated with being misclassified as recent by the Asanté™ HIV-1 Rapid Recency™ assay.
IV. To compare HIV incidence estimated using the Asanté™ HIV-1 Rapid Recency™ assay from a cross-sectional survey with that observed longitudinally in an observational cohort in Rakai.

Uganda 2020-03-16 2023-03-16 Medical and Health Sciences Non-degree Award
Gerry McGivern
ID:
Strengthening health professional regulation in Kenya and Uganda
REFNo: SS336ES

The research aims to develop evidence about how health professional regulation is enacted and experienced by doctors and nurses in Ugandan and Kenyan and ways it might be improved.
UK 2020-03-12 2023-03-12 Social Science and Humanities Non-degree Award
Aala Abdelgadir
ID:
Mosque Mapping Survey
REFNo: SS385ES

Religious institutions play an important role in the daily lives of Ugandans, as in other African countries. Yet, we understand little about the influence of religious institutions on social and political outcomes. This project focuses on the sway of Muslim religious institutions in shaping the opinions and behaviors of congregants. Specifically, we will study how mosques communicate with congregants, what types of messages they deliver, and how messages shape the attitudes and behaviors of congregants.

The research objectives of this project are to:
• Examine variation in sermons, including topics, religious citations, and tone.
• Assess how mosque and imam characteristics influence the nature of sermons.
• Explore how sermons shape congregant religious, social, and political attitudes and behaviors.

USA 2020-03-12 2023-03-12 Social Science and Humanities Degree Award
Scholastic Ashaba
ID: UNCST-2023-R007613
Transition readiness among adolescents living with HIV in Uganda
REFNo: HS512ES

Aim 1: Use qualitative research to elaborate a conceptual model of transition readiness for perinatally-infected ALHIV in Mbarara, Uganda (n=up to 50 in-depth interviews).
Aim 2:Develop and validate a transition readiness scale for perinatally-infected ALHIV (n=340)
Uganda 2020-03-12 2023-03-12 Medical and Health Sciences Non-degree Award
Catherine Abbo
ID:
The Ugandan Early Childhood Phenoscreening Project
REFNo: HS544ES

1. To evaluate the psychometric properties of selected parent-report questionnaires among a community sample of infants and toddlers in Uganda.
2. To identify homogenous subgroups or behavioural risk profiles in a community sample of infants and toddlers
3. To determine the average age of autism spectrum disorder diagnosis in children attending mental health clinics in Mulago and Butabika hospitals
Uganda 2020-03-12 2023-03-12 Medical and Health Sciences Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
Alcohol use, Intimate Partner Violence (IPV) & HIV Risk among Young People in fishing communities on the shores of Lake Victoria, Uganda
REFNo: SS421ES

Aim of the study
The aim of the study is to determine the factors associated with HIV risk among young people in fishing communities on the shores of Lake Victoria, in eastern Uganda.
Objectives of the study
1. To estimate the association between alcohol use and HIV risk among young people in in the fishing communities on the shores of Lake Victoria, Uganda
2. To determine the association between intimate partner violence (IPV) victimization (females) and perpetration (males) and HIV risk among young people in the fishing communities on the shores of Lake Victoria, Uganda

Uganda 2020-03-12 2023-03-12 Social Science and Humanities Non-degree Award
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