Catherine Mwesigwa
ID: UNCST-2019-R000988
|
THE DENTAL WORKFORCE IN UGANDA: A SITUATION ANALYSIS
REFNo: HS532ES
1. To take a census of the dental professionals in Uganda
2. To determine the recruitment levels into public/private employment and retention rates of dental surgeons and specialists in Uganda.
3. To determine the factors which influence attraction to, retention within and attrition from the health care system among dental surgeons and specialists
4. To examine the spatial distribution of actively practising dental professionals and public health dental officers relative to urban- rural and public-private characteristics
|
Uganda |
2020-09-23 |
2023-09-23 |
Medical and Health Sciences |
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Non-degree Award |
|
John Tabuti Robert Stephen
ID: UNCST-2024-R002181
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Development of a Safe and Efficacious Anti-malarial drug from Traditional medicine (DESAT)
REFNo: HS685ES
The aim of this study is to develop an effective anti-malarial phytomedicine. The specific objective are 1) to prioritize malaria treating plants, and to determine 2) efficacy of commonly used herbal medicines, 3) safety of commonly used herbal medicines, and 4) the active compounds in the selected phytomedicines.
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Uganda |
2020-09-23 |
2023-09-23 |
Medical and Health Sciences |
|
Non-degree Award |
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Thereza Piloya Were
ID: UNCST-2019-R000491
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Effect of the COVID-19 pandemic on access to community health care services for common childhood illnesses among children under five years in Wakiso District, Uganda
REFNo: HS802ES
Primary Objectives
1. To determine the utilisation of Integrated childhood community Management (ICCM) services for children aged under 5 years seeking care at the VHTs in three sub-counties in Wakiso district between January and June 2020
2. To determine the outcomes of the sick children under 5 years seen by the VHTS in three sub-counties in Wakiso district.
Secondary objective
3. To determine the utilisation of health facility level services for sick children aged under 5 years referred from the VHTS in Wakiso district during the period of January to June 2020
|
Uganda |
2020-09-23 |
2023-09-23 |
Medical and Health Sciences |
|
Non-degree Award |
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Eve Namisango
ID: UNCST-2021-R014038
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Preparedness to face the COVID-19 pandemic in African hospices and palliative care services: A rapid assessment
REFNo: HS806ES
To determine the preparedness and capacity of palliative care service providers in Africa to respond to the COVID-19 pandemic
To explore the potential consequences of the COVID-19 pandemic on palliative care services and service providers in Africa.
|
Uganda |
2020-09-23 |
2023-09-23 |
Medical and Health Sciences |
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Non-degree Award |
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FLORENCE NALIMU
ID: UNCST-2024-R002900
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Toxicological Evaluation of Aloe Vera Linn and Aloe Ferox Miller Aqueous Leaf and Green Grind Extracts in Wistar Rats.
REFNo: NS138ES
1. To determine the phytochemical groups in the aqueous leaf and green grind extracts of Aloe ferox and Aloe vera.
2. To determine acute oral toxicity effects of Aloe ferox and Aloe vera aqueous whole leaf and green grind extracts in Wistar rats.
3. To determine sub-acute toxicity effects of Aloe ferox and Aloe vera aqueous leaf and green grind decoctions in Wistar rats.
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Uganda |
2020-09-23 |
2023-09-23 |
Natural Sciences |
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Degree Award |
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JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
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Pooled screening of SARS-CoV-2 in the surrounding communities of Makerere University as a cost-effective strategy for reopening.
REFNo: HS912ES
General Objective
To assess the prevalence of SARS-CoV-2 and practices towards its prevention in the surrounding communities of Makerere University and the cost-effectiveness of pooled screening testing strategy to inform reopening of Makerere University.
Specific aims
1.To assess Knowledge, attitudes and practices of people living in areas surrounding Makerere University towards SARS CoV-2 prevention
2.Rapid assessment of high-risk populations around Makerere University for SARS CoV 2 by multi sample pool COVID-19 qRT-PCR technique
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Uganda |
2020-09-23 |
2023-09-23 |
Medical and Health Sciences |
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Non-degree Award |
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Nelson Kaulukusi Sewankambo
ID:
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CRITICAL THINKING ABOUT HEALTH CLAIMS AND CHOICES AMONG SECONDARY SCHOOL STUDENTS IN UGANDA
REFNo: HS916ES
SUB-STUDY 1: Systematic Reviews
General objective:
Our first sub-study addressing main research question 1 above will be a review of existing evidence about strategies for enabling non-professional students to learn to think critically.
Specific objectives:
The primary objective is to provide an overview of what is known from systematic reviews about the effects of strategies to help primary and secondary school students learn to think critically. Secondary objectives are:
i. To map the characteristics of systematic reviews of teaching strategies
ii. To identify needs and priorities for evaluations of teaching strategies based on the findings of the included systematic reviews
iii. To identify needs and priorities for systematic reviews of the effects of teaching strategies for which we are unable to find reliable, up-to-date systematic reviews
iv. To inform the development of a framework for types of teaching strategies
SUB-STUDY 2: Context Analysis
General objective:
The second sub-study will be a context analysis whose main aim will be to establish existing organizational and individual conditions for teaching critical thinking to lower secondary school students in Uganda.
Specific objectives:
i. To explore what demand there is for learning resources for teaching critical thinking about health in secondary schools in Uganda.
ii. To map where teaching critical thinking about health best fits in the national curriculum
iii. To identify and examine relevant resources already in use
iv. To explore conditions for introducing new learning resources
v. To describe what ICT facilities are likely to be accessible in Ugandan secondary schools for teaching and learning purposes, and what, if any, national plans there are for improvements
vi. To identify opportunities and challenges for developing and using digital learning resources to promote critical thinking about treatments
SUB-STUDY 3: Prioritising and sequencing of Informed Health Choices (IHC) Key concepts
The third sub-study will focus on identifying the ideals or key concepts that will be prioritised and ordered for students in lower secondary schools of Uganda for which then learning resources will be developed.
General objective:
To prioritize and sequence the key concepts relevant to recognizing treatment claims and making informed health choices.
Specific objectives:
i. To establish the number of IHC key concepts from a list of 49 to include in learning resources that will be developed for lower secondary school in Uganda.
ii. To determine the order in which the concepts should be learned, and the competencies and dispositions needed to use those key concepts
SUB-STUDY 4: Design and Development of learning resources
General objective:
The fourth sub-study will aim to design learning-resources for teachers and students that they experience positively, that are feasible to use in Uganda, and that lend themselves to translation and adaptation to other contexts.
Specific objectives:
i. To develop learning resources that are relevant, understandable, credible, desirable, well suited in classroom settings and compatible with existing digital resources for improving critical thinking about treatments.
SUB-STUDY 5: Develop, Test and validate of the outcome evaluation tools
General objective:
To develop and test a flexible bank with multiple-choice questions for use as the claim evaluation tools as well as assess the test-taker’s ability to identify claims.
Specific objectives:
i. To develop and test a flexible bank of multiple-choice questions (MCQs) that will constitute the claim evaluation tools.
ii. To assess the validity, reliability and responsiveness of several items addressing prioritised key concepts using Rasch analysis.
SUB-STUDY 6: Evaluation of the learning materials
General objective:
We will seek to evaluate the short-term effects of the learning-resources on lower secondary students’ and teachers’ ability to make individual and policy health choices.
Specific objectives:
i. To evaluate learning-resources designed to teach lower secondary school students and teachers to assess claims about effects of treatments and their ability to make individual and policy health choices.
SUB-STUDY 7: Process Evaluation during the trials
General objective:
To assess the factors that influence the impact of the developed learning resources and how the use of the learning-resources if found to be effective can be scaled up, adapted and translated for use in other contexts.
Specific objectives:
i. To determine the extent to which the intervention was delivered as intended
ii. To document the barriers and facilitators that might influence the implementation and impact of the intervention
iii. To establish factors that might influence its scaling up
iv. To document any additional adverse or beneficial effects as observed.
v. To establish how the use of the learning-resources if found to be effective can be scaled up, adapted and translated for use in other contexts
SUB-STUDY 8: One-year follow -up
General objective:
The seventh sub-study question will seek to evaluate the long-term effects of the learning-resources on lower secondary students’ and teachers’ ability to make individual and policy health choices.
Specific objectives:
i. To evaluate learning-resources one year post the short-term evaluation in the RCT designed to teach lower secondary school students and teachers to assess claims about effects of treatments and their ability to make individual and policy health choices.
|
Uganda |
2020-09-23 |
2023-09-23 |
Medical and Health Sciences |
|
Non-degree Award |
|
Martin Chebet
ID: UNCST-2021-R013909
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A cluster randomised trial to evaluate the effectiveness of
household alcohol-based handrub for the prevention of sepsis,
diarrhoea and pneumonia in Ugandan infants
REFNo: HS919ES
Primary objectives
The principal objective of this study is to determine whether the provision of
alcohol-based hand rub (ABHR) to pregnant women for postnatal household use
is effective for the prevention of severe illness or death during the first 3 months
of life.
Secondaryobjectives
• To determine the impact of ABHR use by the carer on clinical omphalitis.
• To determine the cost and cost-effectiveness of providing ABHR to pregnant
women in rural Eastern Uganda as a way of preventing early childhood severe
illness and death in the first 3 months of life.
• To assess health inequities in participants by comparing the study outcomes in
each wealth quintile.
• To explore current hand hygiene practices and options of improving practice in
rural Ugandan villages
• To explore the mechanisms of action (mediators and moderators) of
caregiver ABHR training on prevention of severe illness or death during the
first 3 months of life.
• To explore the mechanisms of action (mediators and moderators) of caregiver
ABHR training on depression and ABHR use.
|
Uganda |
2020-09-23 |
2023-09-23 |
Medical and Health Sciences |
|
Non-degree Award |
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Bjorn Van Campenhout -
ID: UNCST-2020-R014080
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Demand and supply factors constraining the emergence and sustainability of an efficient seed system in Uganda.
REFNo: SS603ES
The proposed study aims to provide innovative, evidence-based insights on the:
i. Mechanisms that encourage more efficient marketing and distribution of seed and traits at various levels of commercialization and across heterogeneous populations and agro-ecologies (“improving seed supplyâ€), and;
ii. Mechanisms that nudge farmers—youth, women, and smallholders—into using improved varieties and quality seed, including varieties and seed for climate-smart and nutrient-dense crops and traits (“enhancing seed demandâ€).
|
Belgium |
2020-09-23 |
2023-09-23 |
Social Science and Humanities |
|
Non-degree Award |
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Charles Drago Kato Drago
ID: UNCST-2021-R012897
|
Clinical evaluation of novel plasma biomarkers for stage diagnosis among sleeping sickness patients in Uganda
REFNo: HS520ES
1. To identify plasma biomarkers associated with either early or late stage T. b. gambiense disease using proteomics methods and compare with those previously identified for T. b. rhodesiense.
2. To determine the potential of plasma biomarkers identified using proteomics methods in discriminating between early and late stage patients for both T. b. rhodesiense and T. b. gambiense sleeping sickness.
3. To initiate the setup of a biomarker research team and laboratory at Makerere University.
|
Uganda |
2020-09-18 |
2023-09-18 |
Medical and Health Sciences |
|
Non-degree Award |
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Sarah Nanzigu
ID:
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Effects of Co-administration of HAART and Antiepileptic drugs on pharmacokinetics, seizure control and ART outcomes among Ugandans aged 0-24 years.
Short title: Study of Co-medication with HAART and antiEpileptic Drugs
Acronym: Co-HED
REFNo: HS546ES
General Study Objective: To evaluate the pharmacokinetics and clinical effects of HIV and antiepileptic co-medication among Ugandan patients aged 0-24 years.
SUB-STUDY I
This will be a cross-sectional, evaluating short and long-term effects of HAART-AED co-medication on the pharmacokinetics and treatment outcomes of HAART among Ugandans aged 0-24 years.
Specific objectives for sub-study 1
The specific objectives to be addressed during this sub-study will include the following:
1. To determine the effect of combined treatment with HAART and antiepileptic agents on virological control among HIV infected Ugandans aged 0-24 years, attending Baylor HIV clinic.
2. To determine the effect of combined treatment with HAART and antiepileptic agents on the immunological outcomes of HIV infected Ugandans aged 0-24 years, attending Baylor HIV clinic.
3. To determine the effect of combined treatment with HAART and antiepileptic agents on the safety of Ugandans aged 0-24 years, attending Baylor HIV clinic.
The study shall as well address secondary objectives that include the following:
1. To determine the effect of combined treatment with HAART and antiepileptic agents on efavirenz plasma concentrations, among HIV infected Ugandans aged 0-24 years attending Baylor HIV clinic.
2. To determine the effect of combined treatment with HAART and antiepileptic agents on lopinavir plasma concentrations, among Ugandans aged 0-24 years attending Baylor HIV clinic.
SUB-STUDY II
The main objective of this sub-study will be to evaluate the effect of HAART on the pharmacokinetics and clinical outcomes of carbamazepine and sodium valproate among Ugandans aged 0-24 years during 6 months of combined treatments for HIV and epileptic conditions.
Specific Objectives for sub-study II
1. To determine the effect of HAART on the pharmacokinetics of carbamazepine among Ugandans aged 0-24 years, during 6 months of combined treatment for HIV and epilepsy
2. To determine the effect of HAART on the pharmacokinetics of sodium valproate among Ugandans aged 0-24 years, during 6 months of combined treatment for HIV and epilepsy
3. To determine the effect of HAART on seizure control among Ugandans aged 0-24 years, during 6 months of combined treatment for HIV and epilepsy
4. To determine the effect of HAART on the safety of antiepileptic agents among Ugandans aged 0-24 years, during 6 months of co-medication with HAART and either carbamazepine or sodium valproate
Secondarily, we shall determine concentrations of the respective antiretroviral agents (efavirenz or lopinavir). The concentrations of the antiretroviral drugs estimated from study 11, will be compared to those obtained in study 1 in an attempt to establish a direct link of the effect of AEDs on the pharmacokinetics of antiretroviral agents. In addition, we shall attempt to evaluate the likelihood of a concentration-dependent effect of efavirenz on the pharmacokinetics and treatment outcomes of antiretroviral agents.
|
Uganda |
2020-09-18 |
2023-09-18 |
Medical and Health Sciences |
|
Non-degree Award |
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Lucas Ampaire
ID:
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Microbial contamination of locally prepared beverages vended in Kisenyi parish, Kampala: Prevalence, associated factors and utility of rapid diagnostic tests
REFNo: HS586ES
1. To determine the prevalence and factors associated with microbial contamination of locally prepared beverages vended in Kisenyi Parish, Kampala, Uganda.
2. To determine the common contaminating microbial agents in the locally prepared beverages and their antibiotic sensitivity patterns.
3. To assess the performance of MaxSignal® E. coli O157 Strip Test Kit and MaxSignal® Salmonella Strip Test Kit on food-borne pathogens in locally prepared beverages vended in Kisenyi Parish, Kampala , Uganda
4. To develop and evaluate the performance of a local multiplexed strip/cassette for rapid detection of common food contaminants
|
Uganda |
2020-09-18 |
2023-09-18 |
Medical and Health Sciences |
|
Degree Award |
|
Jane Achan Edwin
ID: UNCST-2023-R005498
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Malaria among patients admitted with COVID-19: a case series
REFNo: HS666ES
General Objective: To understand the burden and clinical consequences of malaria among COVID-19 patients
Specific objectives
1. To determine the prevalence of malaria among patients with COVID-19 and to evaluate the risk of malaria following hospital discharge.
2. To determine the magnitude of previous exposure to malaria among patients with COVID-19
3. To document the impact of malaria on clinical outcomes of patients with COVID-19
4. To assess the potential impact of currently used antimalarial drugs (artemether-lumefantrine and dihydroartemisinin-piperaquine) on clinical outcomes among COVID-19 patients prescribed these drugs as per current clinical indications
5. To document the clinical spectrum of malaria among patients with COVID-19
6. To evaluate the potential interactions between COVID-19 and other infectious diseases including HIV/AIDS and TB
7. To describe health worker perspectives on the management of malaria in COVID-19 patients
|
Uganda |
2020-09-16 |
2023-09-16 |
Medical and Health Sciences |
|
Non-degree Award |
|
Nathan Fiala
ID: UNCST-2022-R009060
|
The Long-term Impacts of a cash-based Employment Program in Northern Uganda
REFNo: SS501ES
1.To evaluate the long-term effectiveness of a cash-based youth employment program using a randomized controlled trial.
2. To understand the effect of COVID-19 and restrictions on youth employment
|
USA |
2020-09-16 |
2023-09-16 |
Social Science and Humanities |
|
Non-degree Award |
|
JANE AMUGE
ID:
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Upholding Cooperative Identity as a crucial determinant of Cooperative Resilience: A case study of cooperatives in Uganda
REFNo: SS544ES
1. To identify how cooperatives have optimised their unique character enshrined in their definition, principles and values to cope, remain stable, adapt to situations, innovate and remain resilient in the face of adversity.
2. To establish how adherence or non-adherence to the definition, principles and values of cooperatives have increased their risks, vulnerabilities and contributed to their instability, limited adaptation and innovation thus their lack of resilience.
3. To find out the influence of other factors apart from cooperative identity, on cooperative resilience or the lack of it.
|
Uganda |
2020-09-16 |
2023-09-16 |
Social Science and Humanities |
|
Non-degree Award |
|
Gladys Nakalema
ID:
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DECISIONAL CAPACITY AND COERCION AMONG PATIENTS ENROLLED IN RESEARCH AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: SS479ES
i. To assess the decisional capacity of research participants at Mbarara Regional Referral Hospital (MRRH)
ii. To assess the level of coercion to consent to study participation among research participants at MRRH
iii. To determine the association between decisional capacity and level of coercion to consent to study participation among research participants at MRRH
|
Uganda |
2020-09-15 |
2023-09-15 |
Social Science and Humanities |
|
Degree Award |
|
Annet Nakaganda
ID:
|
Developing a Standardized tool for cancer risk factors Surveillance: A case study of the prevalence of cancer risk factors in Eastern Uganda (CARIFAS)
REFNo: HS754ES
1. Developing a standardized tool for assessing cancer risk factors in Uganda.
2. Estimating the prevalence of cancer risk factors in Mayuge district (Eastern Uganda
|
Uganda |
2020-09-15 |
2023-09-15 |
Medical and Health Sciences |
|
Non-degree Award |
|
Dennis Muhanguzi
ID: UNCST-2019-R001101
|
EVALUATION OF THE SAFETY AND EFFICACY OF VECTOCLORÃ’-PLUS EMULSIFIABLE CONCENTRATE [E.C.]: A RANDOMISED SINGLE-BLINDED POSITIVE CONTROLLED MULTI-SITE ACARICIDE FIELD TRIAL
REFNo: NS129ES
General objectives
To determine the efficacy and safety of Vectoclor®-Plus E.C. (Ceva Santé Animale, Libourne) hereinafter called Vectoclor®-Plus when used on cattle for tick control.
Specific objectives
-To determine the efficacy of Vectoclor®-Plus when used on cattle for tick control
-To determine the safety of Vectoclor®-Plus when used on cattle for tick control
|
Uganda |
2020-09-15 |
2023-09-15 |
Natural Sciences |
|
Non-degree Award |
|
George Lugalambi William
ID:
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UNICEF Handwashing with Soap
REFNo: SS551ES
What factors constrain and prevent individuals and households from washing their hands with soap?
What knowledge, attitudes and practices are prevalent regarding handwashing with soap?
What needs to be done to scale up handwashing with soap initiatives?
Establish barriers to change and how the strategy can efficiently and effectively address them.
|
Uganda |
2020-09-15 |
2023-09-15 |
Social Science and Humanities |
|
Non-degree Award |
|
Numa Memisevic
ID:
|
Breaking stereotypes and remodeling the concept of sexual violence prevention by building resiliency and defense skills among vulnerable women
REFNo: SS542ES
The aim of the foregoing proposal is to test a novel empowerment-based sexual assault prevention
training initiative targeting women at high risk for sexual violence in Uganda. This intervention
focuses on both non-physical and physical measures.
|
Yugoslavia |
2020-09-10 |
2023-09-10 |
Social Science and Humanities |
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Degree Award |
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