Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Immaculate  Atukunda
ID: UNCST-2021-R013573
 WULIRA APP – OCCUPATIONAL HEARING LOSS AMONG INDUSTRIAL WORKERS IN KAMPALA, UGANDA.
REFNo: HS1237ES

1. To determine the prevalence of occupational hearing loss among workers in a steel and iron manufacturing industry in Kampala.
2. To assess the acceptability of using the Wulira App for hearing loss screening among workers in a steel and iron manufacturing industry.

 Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 BASELINE ASSESSMENT FOR NUTRITION INTERVENTIONS IN PALORINYA REFUGEE SETTLEMENT, OBONGI DISTRICT
REFNo: HS1241ES

The overall aim of this baseline study will be to assess the current status of nutrition outcomes, infant and young child feeding (IYCF) and livelihoods indicators among children and WRA, household food security and selected livelihood indicators among refugee households in Palorinya Refugee Settlement.

Uganda 2021-02-22 2024-02-22 Medical and Health Sciences Non-degree Award
Tim Colbourn
ID:
How does a multi-country, multilateral network focused on specific health care improvements evolve and what shapes its ability to achieve its goals?
REFNo: SS659ES

1. To characterise how the QCN initiative was conceptualized and brought together, explore its aims and ethos and understand the global context in which QED arose

2. To explore how the QCN is enacted as a strategy for linking global and national actors

3. To explore case study countries’ contexts and capacities, their interactions with the global QCN and the effects this has on the emergence of the national QCN programme

4. To characterise strategies adopted in countries, their scale, scope and focus, mechanisms of action, the evolution of programmes and what influences them

5. To map the activities of the national programmes at district level and examine the approach to intervention

6. To examine which key data are collected to evaluate the effect of the QCN and assess any effects of network activities


 UK 2021-02-18 2024-02-18 Social Science and Humanities Non-degree Award
Charles Drago Kato Drago
ID: UNCST-2021-R012897
 Establishment of a Biomarker research facility to first track the development of COVID19 novel diagnostics and treatment alternatives in Uganda
REFNo: HS1096ES

1. To establish a biomarker research facility at Makerere University. (Here we shall add more equipment capacity to the existing BSL3 lab at COVAB to execute COVID19 research).
2. To identify and evaluate key SARS-CoV-2 biomarkers in saliva, urine and blood with diagnostic/prognostic or therapeutic potential.
3. To develop biomarker panels (single or multiple analytes) with diagnostic/prognostic or therapeutic potential.

Uganda 2021-02-18 2024-02-18 Medical and Health Sciences Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Mobile Phone enabled Diagnostics for Infectious Disease Diagnosis: Low Cost Tools for Digital Health in Uganda
REFNo: SIR50ES

I. Understanding Digital Health for Infectious Disease in Low Resource Settings
II. Understanding Data Integrity and Security in Digital Health in Africa;
III. Exploring the Relationship between Data and Healthcare Policy;
IV. ICT Devices for Data Acquisition and Communication in East Africa with a focus on Uganda;
V. Capacity Strengthening - Educational Training underpinning Mobile Health.

 Uganda 2021-02-18 2024-02-18 Engineering and Technology Non-degree Award
Christine Aanyu
ID:
Alarm and response systems for addressing maternal and perinatal deaths in Eastern Uganda. A case of re-activation of MPDSR
REFNo: HS635ES

1) To explore the factors that facilitate or constrain the implementation of the MPDSR protocols
2) To develop a collaborative innovation to address the constraints of implementing MPDSR protocols
3) To enhance system wide learning through documenting and sharing of best practices for implementing MPDSR protocols

 Uganda 2021-02-17 2024-02-17 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot
ID:
Paracetamol for Acute Renal Injury in Severe Malaria Trial (PARIST)
REFNo: HS965ES

1. To conduct pharmacokinetic studies of paracetamol in patients with acute kidney injury in severe malaria.
2. To assess the feasibility of conducting AKI in severe malaria in Eastern Uganda.
3. To conduct safety and preliminary effectiveness study for use of paracetamol in ameliorating AKI in severe malaria.

 Uganda 2021-02-17 2024-02-17 Medical and Health Sciences Non-degree Award
Elizabeth Ekong Namukombe
ID:
Work-Based Learning for Baccalaureate Nurses in Uganda: Perception and Current Practice
REFNo: HS810ES

1. Explore the perception of baccalaureate nurses in Uganda on the ease of engaging in Work-based learning. 2. Explore the perception of baccalaureate nurses in Uganda on the usefulness of work-based learning. 3. Describe the current practice of Work-Based Learning among baccalaureate nurses in Uganda. 4. Determine any existing relationship between perceived usefulness and current practice of work-based learning among baccalaureate nurses in Uganda.
Uganda 2021-02-15 2024-02-15 Medical and Health Sciences Degree Award
Jane Namagga Kasozi
ID:
HIV-Associated Neurocognitive Burden: Feasibility of Implementing International HIV Dementia Scale into a Nurse-led HIV Model at TASO centres in southwestern Uganda
REFNo: HS814ES

1.To determine the prevalence of HIV- associated neurocognitive disorders using IHDS among PLWH attending TASO centres in rural Southwestern Uganda.

2.To identify the risk factors associated with HIV- associated neurocognitive disorders among PLWH attending TASO centres in rural Southwestern Uganda.

3.To assess the impact of an education intervention on nurses’ knowledge and skills regarding the use of IHDS in screening and managing HIV- associated neurocognitive disorders

4.To explore nurses' perceptions towards screening and managing HIV- associated neurocognitive disorders using IHDS among HIV positive clients attending TASO centres in rural Southwestern Uganda.

5.To determine the feasibility of implementing IHDS into a nurse-led model of HIV care.

Uganda 2021-02-15 2024-02-15 Medical and Health Sciences Degree Award
Andrew Ssemata
ID:
Exploring and understanding the life skills, sexual, reproductive and mental health needs among adolescents and young people with Spina bifida and Hydrocephalus disability in Sub Saharan Africa; a mixed methods study. (REMHAND)
REFNo: SS703ES

To explore and understand the life skills, sexual, reproductive and mental health needs among adolescents and young people with Spina bifida and Hydrocephalus disability and their significant others (siblings and parents) in Uganda.

Specific objectives
1. Explore and understand the life skills, sexual, reproductive and mental health needs among children and adolescents with disability.
2. Explore the SRH vulnerabilities, and experience (barriers and facilitators) to accessing SRH and mental health services.
3. Explore caregiver (parents and siblings) experiences and perspectives of the health implications of long‐term informal caregiving for children with SBH and disability.
4. Investigate the health, wellbeing and factors affecting the mental health of parents and siblings caring for children with disabilities.

 Uganda 2021-02-15 2024-02-15 Social Science and Humanities Non-degree Award
Bas van Boekholt
ID:
Turn-taking interactions in chimpanzees (Pan troglodytes schweinfurthii) in the wild
REFNo: NS153ES

To shed light on the evolution of language by providing the first systematic insights into the development of turn-taking in chimpanzees
 Netherlands 2021-02-15 2024-02-15 Natural Sciences Non-degree Award
Geoffrey Babughirana Babughirana
ID:
Effect of implementing the timed and targeted counselling (ttC) model on pregnancy outcome and Newborn survival in rural Uganda. A Quaisi experimental study in Hoima and Mansidi district
REFNo: HS574ES

To determine the effect of ttC on pregnancy outcomes and Newborn survival in Rural Uganda

1. To ascertain the extent to which ttC improves uptake of timely Goal Oriented ANC with a focus on the recommended 4 visits
2. To determine whether ttC contributes to the recommended hygienic birthing practices
3. To establish the extent to which ttC improves essential new-born care practices (ENC) during the new born period
4. To ascertain the extent to which ttC fosters positive male involvement in Pregnancy and New Born care
5. To ascertain the relationship between ttC implementation and appropriate pregnancy weight gain by end of Pregnancy.
6. To ascertain the relationship between ttC implementation and appropriate birth weight

Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 A5379: B-ENHANCEMENT OF HBV VACCINATION IN PERSONS LIVING WITH HIV (BEe-HIVe): Evaluation of HEPLISAV-B
REFNo: HS622ES

• To compare the week 12 seroprotection response (SPR) of a two-dose regimen of HEPLISAV-B (Group A, Arm 1) versus the week 28 SPR of a standard three-dose regimen of ENGERIX-B (Group A, Arm 3) in Hepatitis B virus (HBV) vaccine-experienced participants living with HIV (Group A).

• To compare the week 28 SPR of a three-dose regimen of HEPLISAV-B (Group A, Arm 2) versus a standard three-dose regimen of ENGERIX-B (Group A, Arm 3) in HBV vaccine-experienced participants living with HIV (Group A).

• To determine the week 28 SPR of a three-dose regimen of HEPLISAV-B in HBV vaccine-naïve participants living with HIV (Group B).

• To describe adverse events (AEs) reported in each study arm (Groups A and B, separately) over the duration of the study.


Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Clare Cheromoi -
ID:
Interrogating Political Corruption in Post-Independent Uganda: A Historical Perspective, 1962-2017.
REFNo: SS488ES

(1) To describe the transhistorical patterns and evolution of political corruption in Uganda between 1962 and 2017.
(2) To examine the political actors involved in the political corruption scandals experienced in post-independent Uganda.
(3) To explore the proximate and underlying causes of political corruption that are transhistorical in post-independent Uganda.
(4) To assess the transhistorical interrelationships between political corruption and anticorruption responses in post-independent Uganda.

Uganda 2021-02-12 2024-02-12 Social Science and Humanities Degree Award
Leonard Omadang
ID:
PREVALENCE, RISK FACTORS AND ECONOMIC IMPACT OF CYSTIC ECHINOCOCCOSIS IN LIVESTOCK HERDS AMONG THE PASTORAL AND AGRO-PASTORAL COMMUNITIES IN UGANDA
REFNo: A87ES

i. To determine the prevalence of Echinococcosis in livestock slaughtered in selected abattoirs in Uganda.

ii. To determine risk factors associated with cystic echinococcosis in livestock in selected pastoral and agro-pastoral communities in Uganda.

iii. To determine the economic losses of CE in livestock kept by the pastoral and agro-pastoral communities in Uganda.

 Uganda 2021-02-12 2024-02-12 Agricultural Sciences Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Implementation of a Quality Improvement Intervention to Improve Discharge Practices for Children recovering from Severe Infection Using a District model in Gulu and Rukungiri Districts
REFNo: HS926ES

The main objective in implementing this program is to improve patient outcomes for children recovering from Severe Infection though implementation of a multi-faceted quality improvement intervention targeting health workers, care givers and the community health workers.
Specifically we intend to :
1. Evaluate how a targeted behavior change intervention can affect health worker behaviors and facility readiness to assess and manage children during the discharge process.
2. To evaluate the effectiveness of a facility-based linkage to a community based follow-up system to improve post-discharge care for children recovering from severe infections

 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Fred  Bulamba
ID: UNCST-2020-R014888
 The three delays model and Postpartum haemorrhage: a mixed-methods study at a teaching hospital in eastern Uganda
REFNo: HS932ES

Overall aim
The overall aims of this study are to understand how delays impact development of primary PPH (using the three-delays model) and how available preventive and therapeutic interventions are administered.

 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Janet Lewis I
ID:
Reducing Prejudice Against Refugees Pilot
REFNo: SS662ES

The vast majority (85%) of the world’s political refugees live in developing countries, according to UNHCR. As of early 2019, Uganda was home to over one million refugees from South Sudan, and had the largest refugee/asylum-seeker population in Africa (ACCORD 2019). Uganda has a strong national commitment to hosting refugees that is reflected in its immigration policies, leading some to call it a “melting pot” of regional nationalities. Still, its population faces challenges absorbing these refugees that are common to host countries. Relations are often strained between the refugee population and Ugandans, some of who perceive refugees as unwelcome competition for local resources and services (World Vision 2018; UNHCR 2018; ACCORD 2019).
This study will allow us to better understand the perceptions of Ugandans towards South Sudanese refugees, and measure both the extent of anti-refugee prejudice there and whether a perspective-taking intervention is effective at reducing prejudice. This knowledge will be crucial for understanding how best to design a later, larger study, which could substantially advance knowledge about prejudice reduction towards refugees in Uganda.
Furthermore, this study will provide a useful indication about whether our full version of this study will be able to measure spillover of the treatment through social networks; we will ask respondents in our endline survey about whether and with whom respondents discussed the intervention. Prejudicial attitudes are socially reinforced; changing one person’s mind may be difficult if that person’s peers still hold prejudicial beliefs. Likewise, if many of one’s peers have begun to reconsider their own prejudices, one may be encouraged to do so as well. Our prior work leads us to expect the information to spread widely, and some change in attitudes and behavior, but only for those connected to a treatment recipient via certain kinds of social ties (Larson and Lewis 2017, 2018). Practitioners often assume that interventions spread from a subset of individuals to their broader community through felicitous spillovers. If this pilot is successful, our full study will be among the first to measure whether and how this occurs for prejudice reduction through networks. This knowledge could, among other things, lead to more efficient designs of community prejudice-reduction projects. Moreover, even if spillover effects are not present, the full study will be able to detect how news of the intervention spreads through local networks. Doing so will provide rare, direct evidence of information dissemination through word-of-mouth networks, which is useful for the design of programs aimed at seeding any type of public service message – from news intended to diffuse conflicts, to information about a new technology that promises to better hold politicians accountable or improve public health.

Our pilot study therefore addresses four questions:
(1) What is the extent of anti-refugee prejudice among Ugandans living in villages in West Nile?
(2) Do positions towards refugees correlate with their positions in village social networks?
(3) Can a brief conversation oriented towards taking the perspective of South Sudanese refugees reduce Ugandans’ prejudice toward them? If so, does the effect persist after 2-3 weeks?
(4) To what extent does news spread about this perspective-taking exercise, and through which types of contacts?
 USA 2021-02-12 2024-02-12 Social Science and Humanities Non-degree Award
AGGREY DHABANGI
ID:
Hemolytic Disease of the Newborn in Uganda: Burden and Clinical Characteristics (Short title: HDN in Uganda)
REFNo: HS1089ES

To determine the prevalence of HDN due to RhD among newborn infants with jaundice admitted to Kawempe National Referral hospital in Uganda.
 Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 PREVALENCE AND RISKS ASSOCIATED WITH METABOLIC SYNDROME IN CHILDREN AND ADOLESCENTS LIVING WITH HIV IN UGANDA. A PILOT STUDY
REFNo: HS1128ES

i To determine the prevalence of MetS among children and adolescents living with HIV in Uganda.
ii To identify risks factors for the development of MetS in children and adolescents living with HIV.

Uganda 2021-02-12 2024-02-12 Medical and Health Sciences Non-degree Award
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