Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Abel Wilson Walekhwa Wilson
ID: UNCST-2021-R011571
 Ecological niche modelling for Rift Valley Fever Disease Transmission in selected districts in Uganda
REFNo: HS2019ES

1.To describe the epidemiological characteristics of RVF outbreaks in Uganda for 2013-2021
2.To Profile the clinical presentation of previous RVF cases at farm level
3.To build the epidemiological Livestock network predictive model for RVF outbreaks
4.To build an ecological niche model for next RVF outbreaks in Uganda
5.To build a model for a one health cost effective intervention suitable for Uganda in mitigating RVF outbreaks.
6.To build a cost benefit Analysis for introduction of RVF vaccination programme in Uganda

 Uganda 2022-02-10 2025-02-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Christopher Udry
ID:
Seeding Innovation through Reality TV
REFNo: A178ES

he project will improve our understanding of farmers’ learning and adoption process by studying the role of information provided to urban and rural network members. Given the low marginal costs of distribution, programs like SSU have a high potential to deliver agricultural advisory services at scale.,to understand if reality TV can help to enhance the knowledge and adoption of recommended agricultural practices among farmers in Uganda.,
 USA 2022-02-10 2025-02-10 Agricultural Sciences Non-Clinical Trial Non-degree Award
ALEX KAYONGO
ID: UNCST-2019-R001641
 Airway Microbiome and Th17-mediated inflammation in COPD among HIV-infected individuals in a rural Ugandan cohort ACRONYM: HIV-LUNG MICROBIOME (HLM) study
REFNo: HS2035ES

Study aim:
To investigate airway microbiome-driven Th17 mediated inflammation in COPD among HIV-infected individuals

Specific objectives
1. To establish a relationship between airway microbiome and Th17/Treg cellular phenotypes among HIV-infected individuals with COPD.

2. To investigate bacterial mediated Th17 up-regulation of pro-inflammatory genes among HIV-infected individuals with COPD.

3. To investigate the role of bacterial outer membrane vesicles (OMVs) in mediating dysbiosis driven Th17 immune responses among HIV individuals.

 Uganda 2022-02-10 2025-02-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SAFINA MUTUMBA NA
ID:
SCHOOL-COMMUNITY PARTNERSHIPS AND IMPLEMENTATION OF INTEGRATED EARLY CHILDHOOD CARE EDUCATION SERVICES IN PRE-PRIMARY SCHOOLS IN KIRA MUNICIPALITY, WAKISO DISTRICT
REFNo: SS1104ES

3. To assess the relationship between School-Service Providers Collaboration and Health Care Practices. ,2. To investigate the contribution of School-Local Leaders Collaboration on the strength of Protection Policies. ,1. To establish the influence of School-Parents Engagement on Stimulation Activities.,
 Uganda 2022-02-08 2025-02-08 Social Science and Humanities Non-Clinical Trial Degree Award
Adam Branch
ID:
Fuelling Violence to Fuelling Peace: Charcoal and Environmental Justice in East Africa
REFNo: SS1157ES

Primary Research Objective: To determine how charcoal can contribute to sustainable peace instead of social and environmental harm. Secondary Research Objectives: Determining the power structures in the charcoal sector. Determining what charcoal extraction practices are used, and what their impact upon ecosystems is. Mapping the relations between communities and charcoal landscapes. Discerning the new pathways to environmental justice that are emerging among communities.
 USA 2022-02-08 2025-02-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gilberto Borri
ID:
Mobility, Migrations and Refugees in East Africa:The Case of Uganda.
REFNo: SS1160ES

The research project aims to analyse the multifaceted dynamics of mobility and migration in East Africa with a focus on Uganda.

Specifically, we propose to concentrate on the following topics:

1 – To analyse mobility and migration patterns in relation to Ugandan contemporary models of hospitality from historical, socio-anthropological and gender responsive perspectives

2 – To explore the socio-economic relations between refugees, migrants and hosting communities

3 – To analyse the environmental impact of refugees and migrants on local contexts

4 – To analyse the co-relation between humanitarian development programs on refugees and host communities

5 – To analyse the importance of religions and the diversity of health care systems among refugee and migrant communities
 Italy 2022-02-08 2025-02-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Capacity building for a Centre of Design, Innovation and Translational Excellence (CITE) for clinical trials of healthcare technologies in SS Africa
REFNo: SS1181ES

To determine the current standards and policies governing the clinical trials and regulation of IMDs in Uganda,To determine the challenges and opportunities in clinical trials of IMDs in Uganda,To determine the requirements and stages for clinical trials of IMDs in Uganda,To map existing knowledge about the systems and processes for clinical evaluation of locally made Investigational medical Devices (IMD) amongst key stakeholders in Uganda,
 Uganda 2022-02-08 2025-02-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Strengthening Interdisciplinary Research in Technology Translational Pathways for Improved Maternal and Child Health in Uganda
REFNo: HS2056ES

The general objective of the study is to strengthen interdisciplinary research in Technology translational pathways for improved maternal and child health in Uganda,To build a network of researchers including social scientists, data scientists, health services researchers, business researchers and implementational scientists in order to improve innovations and use of appropriate medical technologies for maternal and child health for use in Uganda.,To determine the number of med-Tech innovations that have managed to translate into marketable products in Uganda.,To determine the organizations and requirements involved in Medical Technology translation in Uganda. ,To Map current research/researchers, approaches, and bottlenecks in medical devices translation in Uganda and the UK. ,
 Uganda 2022-02-08 2025-02-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nora Slania Esther
ID: UNCST-2021-R012549
 The evolutionary roots of curiosity: Understanding the interplay of chimpanzee (pan troglodytes) exploration tendencies, problem-solving skills, and neophobia
REFNo: NS319ES

We plan to identify conditions and factors that promote or suppress curiosity, as defined by
an interplay of exploration tendencies and neophobia, in chimpanzees in their natural
environment
 Germany 2022-02-04 2025-02-04 Natural Sciences Non-Clinical Trial Degree Award
Mulumba Mathias Bwanika
ID:
Scaling the School readiness Initiative by Strengthening School and Community Capacities for the Adoption of Play-Based Learning in Uganda
REFNo: SS1161ES

To strengthen coordination structures in the Ministry of Education and Sports at national, district and regional levels for effective support of PBL ECDE centers in Uganda,To strengthen the capacity of teacher educators, teachers, parents, education leaders, and the community members in the support of Play-based learning (PBL) approaches for effective school readiness and transition of learners from pre-school to primary schooling.,To build capacity of teachers, teacher educators’ and parents in the development of play-based learning materials for use in ECDE classes in Uganda ,To examine the current play-based learning frameworks in ECDE to generate information to support policy strengthening to integrate play-based learning and scaling up of SRI in Uganda ,To strengthen the capacities of schools and communities for the adoption of play-based learning and curricula to contribute to enhanced school readiness and transition in ECDE and early grades of primary education in Uganda,
 Uganda 2022-02-04 2025-02-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Elizabeth namukwaya namukwaya
ID: UNCST-2021-R013177
 Exploring the needs and lived experiences of people with chronic disease among the refugee and host communities of Obongi district and the experiences of Village Health Teams workers in providing palliative care in Obongi and Adjumani districts
REFNo: HS1773ES

Primary Objective
1. To determine the prevalence of chronic illness and to understand the palliative care needs of refugee and host populations, their multidimensional experiences of living with chronic life limiting illnesses and VHTs experiences of caring for patients with chronic illnesses and offering mentorship support to other VHTs.
1.4.2 Specific Objectives:
1. To determine the prevalence of patients with chronic life limiting illnesses among people living within the villages served by selected VHTs in the refugee and host communities of Obongi and Adjumani district in Uganda
2. To determine and explore palliative care needs and multidimensional experiences of patients with chronic life limiting illnesses in Obongi district in Uganda
3. To Understand the experiences of VHTs in caring for those with palliative care needs and in offering mentorship to other VHTs to provide PC in Obongi and Adjumani districts.

 Uganda 2022-02-04 2025-02-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Ogwang Sam
ID: UNCST-2021-R013566
 OPTIMUM EFFORT AND SUSTAINABLE YIELD OF THE FISHERIES OF LAKE KWANIA USING CATCH AND EFFORT DATA
REFNo: NS316ES

2. Conduct a catch Assessment Survey to quantify the current level of fish catches (catch) from the lake,1. Conduct a frame survey to establish the number and characteristics of fishing effort (Boats and Gear) on Lake Kwania,Fit Schaefer & Fox models to catch and effort data to determine the biological Maximum Sustainable Yield (MSY) and the corresponding optimum fishing effort (fMSY) and stable population size (BMSY) for the fishery. ,Conduct a catch Assessment Survey to assess the current level of fish exploitation (catch) on the lake,Conduct a frame survey to assess the characteristics of fishing inputs (effort) on Lake Kwania,This research is designed to assess the level of fisheries exploitation and determine the optimum fishing effort and sustainable yield for the fisheries of Lake Kwania. ,
 Uganda 2022-02-04 2025-02-04 Natural Sciences Non-Clinical Trial Degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 M-Suubi: A Multi-Level Integrated Intervention to Reduce the Impact of HIV Stigma on HIV Treatment Outcomes among Adolescents Living with HIV in Uganda
REFNo: SS1166ES

Aim 1: Examine the impact of M-Suubi on HIV viral suppression (primary outcome); and adherence to HIV treatment (keeping appointments, pharmacy refills, pill counts), and retention in care (secondary outcome).

Aim 2: Examine the effect of M-Suubi on Stigma (internalized anticipated, and enacted), with secondary analyses to explore hypothesized mechanisms of change (e.g. depression) and intervention mediation.

Aim 3: Assess the cost and cost-effectiveness of each intervention condition.

Aim 4: Qualitatively examine: a) participants’ experiences with HIV stigma, HIV treatment adherence, and the intervention; and 2) educators’ attitudes towards ALHIV and experiences with GED-HIVSR, and program/policy implementation post-training.

Aim 5: Conduct formative work (focus group discussions) to understand the needs of depressed ALHIV.

 Uganda 2022-02-04 2025-02-04 Social Science and Humanities Clinical Trial Non-degree Award
Emmanuel Omony Otto
ID:
Social accountability as a mechanism for promoting family planning uptake in post conflict northern Uganda
REFNo: SS1169ES

Explore how social accountability can be strengthened to improve uptake of family planning services in Gulu and Pader Districts.,Explore the effects of social accountability on fertility preferences in post conflict Gulu and Pader districts.,Examine the influence of social accountability on the availability, demand and utilisation of family planning services in Gulu and Pader districts.,Explore the effects of conflict on institutions and governance structures of social accountability and; effects on the provision of family planning in post conflict districts of Gulu and Pader. ,
 Uganda 2022-02-04 2025-02-04 Social Science and Humanities Non-Clinical Trial Degree Award
Rhoune Ochako
ID:
MASS DRUG ADMINISTRATION COVERAGE EVALUATION SURVEY FOR NEGLECTED TROPICAL DISEASES
REFNo: SS1175ES

The goal of the coverage survey is to verify Mass Drug Administration (MDA) coverage by survey areas (e.g., district, Implementation Unit (IU)). Specifically, the survey will address the following objectives:

a) To understand the reasons for non-compliance among those who reported no treatment

b) To assess the status of the behaviour change communication (BCC) activities in the program

c) To estimate the cost to treat an individual

d) To approximate the cost of verifying whether an individual has been treated
 Kenya 2022-02-04 2025-02-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
 Violence Against Children and Youth Surveys (VACS) Cognitive Testing of Gender Attitude and Norm Measures Among Youths in Uganda
REFNo: SS1170ES

To understand the processes participants (13-24 years) go through and the meanings they derive from the new gender measures to be included in the VACS core questionnaire.

1. To evaluate participants' interpretation of the gender measures, consider and weigh relevant aspects of their lives and formulate a response based on those considerations.
2. To test and refine gender measures that are understandable to 13-24-year-old study participants for inclusion in the core VACS questionnaire and future VACS administration.
3. To identify context specific relevance of proposed gender measures in the administration of VACS in Uganda.
 Uganda 2022-02-04 2025-02-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Kanyerezi
ID:
Characterizing microbial diversity and resistome in urban sewage using shotgun metagenomics in Kampala, Uganda
REFNo: HS1832ES

Primary objective: To characterize the microbial diversity and resistome in urban sewage using shotgun metagenomics in Kampala, Uganda Secondary objectives: 1. To identify and characterize antibiotic-resistant bacteria in urban sewage in Kampala 2. To determine the urban sewage resistome
 Uganda 2022-02-03 2025-02-03 Medical and Health Sciences Non-Clinical Trial Degree Award
SIMON ARUNGA
ID: UNCST-2021-R013498
 CAPACITY OF THE HEALTH SYSTEM IN MANAGEMENT OF GLAUCOMA IN SOUTHWESTERN UGANDA.
REFNo: HS2016ES

4. Explore the health provider-based barriers for glaucoma screening and treatment in Southwestern Uganda.,3. Describe the capacity of managing glaucoma at the regional referral hospitals in Southwestern Uganda.,2. Describe the capacity for glaucoma screening at the primary health centres in Southwestern Uganda.,1. Determine the proportion of glaucoma among patients presenting to primary health centres in Southwestern Uganda.,Conduct a baseline assessment to describe the capacity of the health system to manage glaucoma.,
 Uganda 2022-02-03 2025-02-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WILBROAD ARYATWIJUKA
ID:
Supply chain efficiency of relief operations in Uganda
REFNo: SS1037ES

To examine the relationship between stakeholder competencies and supply chain efficiency of relief aid organizations in Uganda.,To determine the mechanisms of improving supply chain efficiency of relief operations in Uganda during the crisis.,To examine the challenges of relief operations during covid19 pandemic Uganda.,To establish the factors that affect supply chain efficiency of relief operations in Uganda.,
 Uganda 2022-02-01 2025-02-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Emmy Okello
ID: UNCST-2020-R009792
 Remote Ischaemic Conditioning in STEMI patients in sub-Saharan AFRICA: The RIC-AFRICA trial
REFNo: HS1865ES

RIC will reduce the rates of all-cause death and early post-myocardial heart failure by approximately 25% when compared to sham control.,The RIC-AFRICA trial will investigate the effect of RIC in STEMI patients on the rates of all-cause death and early post-MI heart failure (pre-discharge HF and hospitalisation for HF at 30 days post-MI,) when compared to sham control,
 Uganda 2022-02-01 2025-02-01 Medical and Health Sciences Clinical Trial Non-degree Award
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