Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ismay Milford Milford
ID:
The ‘Information Sector’ in East Africa, 1950s-70s: The professionalisation of journalism, broadcasting and information officers
REFNo: SS730ES

This project is a history of the ‘information sector’ as it emerged in dialogue with global patterns over the period of decolonisation in East Africa (c. 1950s-70s). I understand information not as a given technology inevitable to the language of the developmentalist state in mid-twentieth century Africa, but as a culturally constructed and moulded idea through which we can access connections that East African people of various ‘information professions’ forged with the wider world. This is in some sense a pre-history of the global debates around information that resulted in the call for a ‘New World Information and Communication Order’ in the 1970s. It argues that East Africa played an important role in the disciplinary shift from ‘information science’ to ‘mass communication’, and in the understandings of knowledge production that informed postcolonial theory.
UK 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Pierre ABOMO
ID:
Strengthening national capacity for tsetse control in Uganda
REFNo: SS725ES

1) Conduct semi-structured interviews with key personnel at COCTU and the District level to fully understand the current level of execution of the action plan for strengthening the capacity to for implementing tsetse control in Uganda

2) Conduct participatory workshops at COCTU and the District level to collaboratively assess the progress towards the establishment of a stronger and independent tsetse control system in Uganda (based on findings from objective 1).
UK 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Eddie Wampande Mujjwiga
ID:
An evaluation of African swine fever presentation and distribution in Uganda
REFNo: NS266ES

i. Conduct a serologic, clinical, pathological, and molecular diagnostic survey of swine at a large slaughterhouse near Entebbe and Kampala, Uganda to understand the relationship between the disease status and the diagnostic status of the animals as related to Africa swine fever.
ii. Conduct a serologic analysis slaughterhouse swine to measure the immune response against exposure to the Ornithodoros moubata tick, the ASF reservoir vector in Africa.
iii. Conduct trace back to hotspots to evaluate biosecurity and conduct training of veterinarians and producers on the clinical and pathological signs of Africa swine fever.
iv. Sequence PCR positive samples to better characterize the ASF genotype and strain and its disease presentation.
v. Discuss the findings with the Ministry of Agriculture, Animal Industries, and Fisheries.

 Uganda 2021-07-13 2024-07-13 Natural Sciences Non-degree Award
Charles Batte
ID: UNCST-2021-R013587
 ASSESSING THE SOCIO-ECONOMIC IMPACT OF COVID-19 PANDEMIC ON SMALLHOLDER FARMERS’ HOUSEHOLDS AND SCHOOL-GOING CHILDREN IN BUDUDA DISTRICT, UGANDA.
REFNo: SS789ES

To assess the impact of the COVID-19 pandemic on school-going children in Bududa district.,To assess the socio-economic impact of the COVID-19 pandemic on smallholder farmers’ households in Bududa district.,
 Uganda 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
omia Obel Francis Patrick
ID:
MULTI-STAKEHOLDER PARTICIPATION IN NATIONAL BUDGETING IN UGANDA By Francis Patrick Omia
REFNo: SS870ES

The purpose of this study is to assess the effect of multi-stakeholder participation in national budget preparation
The specific objectives of the study are as follows;
1. To examine mechanisms for Multi-stakeholder participation in budget preparation planning.
2. To analyze Multi-stakeholder participation in budget deliberation.
3. To assess Multi-stakeholder participation in budget preparation outcomes.

Uganda 2021-07-13 2024-07-13 Social Science and Humanities Non-Clinical Trial Degree Award
Nitin Wadhwa
ID:
Investigating crop raiding and ranging of habituated mountain gorillas close to park boundaries in the Buhoma sector of Bwindi National Park, Uganda.
REFNo: NS263ES

1. In this proposed study, we will walk jungle trails taken by forest rangers in the Buhoma sector to find and map signs of gorilla presence and human related activity. 2. Based on the spatial mapping exercise and density of recorded signs in a particular area, we will identify areas of high gorilla movement and ascertain how close to park boundaries gorillas are venturing and also how high are disturbance factors like human activity along the boundaries of the park. 3. We will also walk and survey the approximately 10 kms of park boundary relevant to our study (See Figure 3 in Appendix) in the Buhoma sector to map land use and cropping pattern along the edges of park (upto 150 metres). 4. Based on the the survey excersise along the boundaries of the park, we will map the land use patters and crops planted along the boundaries to create a spatial map to understand human activities along the edge park. 5. We will use data obtained from previous objectives and extrapolating it in conjunction with already existing research, we will draw conclusions and give recommendations.
India 2021-07-13 2024-07-13 Natural Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Mapping service pathways across the cancer disease trajectory in Kampala; a retrospective cohort study of timing and access to services
REFNo: HS805ES

1. To determine the number of patients accessing cancer services at Uganda Cancer Institute, Mulago Palliative care Unit, Kawempe Home Care and Hospice Africa Uganda from 2018 across 2019
2. To Identify source of referrals and target of onward referrals across these above services
3. To determine case mix across cancer services
4. To determine median number of days between referral to cancer care services and death for the study sample
5. To Identify variation in access to and referrals to cancer services by sex, age, ethnicity, diagnosis, and geographical location of residence
6. To Depict cancer pathway for patients from diagnosis to death in Kampala, Uganda

Uganda 2021-07-12 2024-07-12 Medical and Health Sciences Non-degree Award
Franklin Higenyi
ID:
Gender and Public Health Space:A case of Female Doctor's career progression in Uganda Public Medical Services
REFNo: SS732ES

The study will investigate the factors that determine FDs’ career progression in UPMS.
1.4.1. Specific Objectives
1.4.1.1. To assess gender differences in career progression of female and male doctors in UPMS.
1.4.1.2. To analyze the socio-cultural and institutional factors that influence career progression of FDs in UPMS space.
1.4.1.3. To asses lived experiences of those who have managed to have career progression.
 Uganda 2021-07-12 2024-07-12 Social Science and Humanities Degree Award
Cosmas Mwikirize
ID:
Efficacy of a Deep Learning-aided Platform for Diagnosis of Breast Cancer using Ultrasound Images in the Ugandan Population
REFNo: SIR57ES

General Objective: To develop and evaluate the efficacy of a deep learning-based computer-aided platform for screening of breast cancer in the Ugandan population. Specific Objectives: 1. To collect, and curate and label breast US data from ECUREI Radiology department. 2. To develop deep learning models for lesion detection and pixel-wise segmentation in breast US images. 3. To integrate the learned models in an offline computer-aided detection platform for breast cancer, and clinically evaluate its performance. 4. To develop and integrate learned models for breast cancer detection, in a real-time portable ultrasound imaging platform.
Uganda 2021-07-12 2024-07-12 Engineering and Technology Non-degree Award
Onesmus  Ahabwe Magezi
ID:
COMMON CAUSES OF ABNORMAL VAGINAL DISCHARGE AND ANTIBIOTIC SUSCEPTIBILITY AMONG WOMEN ATTENDING THE GYGAECOLOGICAL OUTPATIENT CLINIC OF MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1456ES

1.To determine the common bacterial isolates among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital.
2.To describe the antibiotic susceptibility patterns of bacterial isolates among women with abnormal vaginal discharge attending the gynecological clinic of Mbarara Regional Referral Hospital.
3.To identify the factors associated with antibiotic resistance to commonly used antibiotics among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital

 Uganda 2021-07-12 2024-07-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Josylin Ekochu Arimpa Bananuka
ID:
Corporate Governance Practices and Performance of Pharmaceutical Manufacturing Firms in Uganda
REFNo: SS571ES

i. To analyze the effect of corporate leadership on the performance of pharmaceutical manufacturing firms in Uganda
ii. To assess the effect of boards of directors on the performance of pharmaceutical manufacturing firms in Uganda
iii. To investigate the consequences internal control systems have on the performance of pharmaceutical manufacturing firms in Uganda

Uganda 2021-07-09 2024-07-09 Social Science and Humanities Degree Award
Francis Ocheng
ID:
Helichrysum odoratissimum: Isolation and identification of bioactive compounds and their effects on oral bacteria
REFNo: HS1441ES

2-To determine whether the isolated and purified compounds from Helichrysum odoratissimum maintain their antibacterial effects on oral bacteria,1-To isolate and identify the bioactive compounds in the plant Helichrysum odoratissimum plant extracts ,The general objective of the study is to isolate and identify the bioactive compounds in the Helichrysum odoratissimum plant extracts and also further investigate the effects of the isolated compounds on oral bacteria ,
 Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Implementation of a "bundle of care" to improve anticoagulation control in patients receiving warfarin in Uganda and South Africa
REFNo: HS1422ES

Primary objective is to evaluate whether implementation of warfarin bundle improves time in therapeutic range

Secondary objectives are:
-To evaluate whether implementation of the warfarin bundle improves time to achieving a therapeutic INR
-Whether implementation of the warfarin bundle affects the occurrence of adverse events(death, bleeding and thrombotic events)
-whether staff find the interventions contained in the bundle acceptable
-To explore patients' experiences and acceptability of the package of care, and
-Whether the bundle represents good value for money
 UK 2021-07-09 2024-07-09 Medical and Health Sciences Clinical Trial Non-degree Award
Maureen Ayikoru
ID:
REVISED PROPOSAL IN RESPONSE TO THE OUTCOME OF ROUND 1 OF COMMITTEE REVIEW OF THE PROJECT “INDIRECT IMPACTS OF COVID-19 ON HEALTHCARE SYSTEMS: A CASE STUDY OF UGANDA’S HEALTHCARE PROFESSIONALS”
REFNo: HS1524ES

To document what lessons can be learnt from Uganda’s response to COVID-19,To analyse the impact of information and communication technologies and the media, including digital, print and broadcast media in containing the COVID-19 pandemic in Uganda.,To analyse what if any, political economy factors influence misinformation, resource reallocation and prioritisation during the ongoing pandemic and to document the perceived effects on the entire healthcare system including those most vulnerable,To identify what threats COVID-19 has had on physical, psychosocial, and overall well being of HCPs and to assess what if any formal and informal coping mechanisms have so far been available to them,To generate empirical evidence on the indirect impacts of Uganda’s response to COVID-19, focusing on the healthcare professionals.,
 Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
 Efficacy and safety of artemether-lumefantrine, pyronaridine-artesunate, artesunate-amodiaquine and dihydroartemisinin – piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda.
REFNo: HS1363ES

The general objective of this study is to assess the therapeutic efficacy and safety of artemether-lumefantrine (AL), pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP) for the treatment of uncomplicated P. falciparum malaria in three sentinel sites in Uganda.
The primary objectives are:
• to measure the clinical and parasitological efficacy of 4 artemisinin-based combination therapies (ACT), artemether-lumefantrine (AL) Pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP).
• to differentiate recrudescence from new infection of Plasmodium falciparum by molecular techniques.
The secondary objectives are:
• to evaluate the incidence of adverse events; and
• to determine the polymorphism of molecular markers mediating resistance for Artemsinin, Pyronaridine, Piperaquine and Lumefantrine resistance.
• to determine the blood concentration of Lumefantrine after treatment with Artemether- Lumefantrine .


 Uganda 2021-07-08 2024-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aubryn Sidle Allyn
ID:
Emplacing Agency in Girls' Education Practice: An Evaluation of Impact
REFNo: SS651ES

1. To evaluate the impact of CDOs’ programs on girls' Agency outcomes.
2. To understand how and why programs influence agency in adolescent girls, and what aspects of program design impede or speed this development.
3. To understand the relationship between girls’ agency and educational outcomes.
4. To evaluate the relationship between girls’ agency and teenage pregnancy incidence and determine what effect, if any, increased agency has on teenage pregnancy.
 USA 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
Angelique Murorunkwere
ID:
DIAGNOSTIC DELAY AND ITS CAUSES AMONG PEDIATRIC CANCER PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL CANCER UNIT
REFNo: SS857ES

1. To determine the average time between onset
of symptoms and diagnosis among children
with cancer at MRRH
2. To outline caregiver self-reported reasons
for delayed diagnosis among children with
cancer at MRRH
3. To establish the correlates of delayed
diagnosis among children with cancer at
MRRH

 Rwanda 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
Roseline Katusiime
ID:
Detecting and analysing micronutrient gaps in dietary patterns in Western Uganda: A comparison of different methods
REFNo: A122ES

1. To compare the 24-hour recall method with direct observation and weighing of food portions, so as to generate knowledge on their accuracy and make expert recommendations by the end of 2021.
2. To use the CIMI to identify nutrient deficiencies in particular gaps of Vitamin A, Zinc and Iron and generate CIMI based recommendations and suggestions on improved diets for the research participants at the end of June 2021.
3. To calculate the costs of improved diets and develop recommendations on affordable nutrient adequate diets for study participants by the end of 2021
4. To assess the advantages and disadvantages of different strategies used by development organizations in western Uganda in encouraging communities to embrace affordable nutrient adequate diets and feeding practices by June 2021

Uganda 2021-07-07 2024-07-07 Agricultural Sciences Degree Award
Deborah  Ojiambo
ID:
Efficacy of Group Activity Adherence Counselling (GAAC) for Adolescents with Unsuppressed HIV viral load at three large HIV clinics in Uganda: Randomized controlled trial
REFNo: SS805ES

1.To examine the barriers such as behavior problems and mental health problems to adherence experienced by adolescents living with HIV.
2.To evaluate the efficacy of GAAC in addressing barriers to adherence among adolescents living with HIV.

3.To assess whether GAAC is associated with viral load suppression, among adolescents living with HIV compared to Standard Service Provision (SSP)
 Uganda 2021-07-07 2024-07-07 Social Science and Humanities Clinical Trial Non-degree Award
Omony Geoffrey
ID:
Safeguarding the war-affected community in Gulu district in Northern Uganda
REFNo: SS830ES

1) To explore and document the impact of research and projects on former child soldiers, both the benefits and the harms, and capture how future projects which focus on the war-affected community can benefit them and what they require for their empowerment
2) to contribute new evidence on the impacts, both direct and indirect, of COVID-19, on persons with disabilities, led by persons with disabilities, with a focus on war-related disabilities in Northern Uganda. This evidence and data will include solutions for disability-inclusive pandemic recovery informed by persons with disabilities
3) to contribute towards the evidence and literature on safeguarding war-affected and post-conflict communities, and create outputs which are accessible to various audiences, including policymakers, academics, journalists, NGOs, and general public
4) to build the esteem of ex-child soldiers, persons with disabilities, and other war-affected groups in Northern Uganda, through involving them in participatory-action research, the design of outputs, and dissemination activities to foster confidence-building, inclusion, and empowerment
Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
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