Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Agnes Nyabigambo
ID:
Effectiveness of clinic-based patient-led HPV DNA self-sampling among HIV-infected women in Uganda.
REFNo: HS2084ES

1. To assess the difference and associated factors of uptake of clinic-based compared to home-based HPV self-sampling approach among HIV infected women in rural Uganda. 2. To identify factors associated with the prevalence of HPV among HIV-infected women in rural Uganda. 3. To determine factors influencing sample viability HPV self-collected samples in clinic arm compared with home -based arm. 4. To explore the facilitators and barriers of clinic-based compared to home-based HPV self-sampling approaches among HIV-infected women in rural Uganda. 5. To estimate the cost-effectiveness of the clinic-based approach compared to the home-based HPV-DNA self-sampling among HIV-infected women in rural Uganda.
Uganda 2022-06-08 15:13:10 2025-06-08 Medical and Health Sciences Clinical Trial Degree Award
Lorraine Oriokot Amuyan Nabwire
ID:
The implementation of social Accountability in undergraduate medical education at Makerere University School of Medicine
REFNo: HS2203ES

1) To evaluate the implementation of social accountability in undergraduate medical education at Makerere University School of Medicine. 2) To explore the perceptions, attitudes, and experiences of stakeholders regarding social accountability at Makerere University School of Medicine. 3) To develop a competency-based teaching and learning framework for social accountability. 4) To evaluate the readiness to adopt the competency-based teaching and learning framework at Makerere University School of Medicine.
Uganda 2022-06-08 15:12:02 2025-06-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
The Pelvic Floor Disorders (PFD) Study: Validation of PFDI-20, PFIQ-7, and evaluation of pelvic floor disorders in parous Ugandan women.
REFNo: HS2236ES

To determine the prevalence of Pelvic Floor Disorders PFD among a cohort of

parous women and to translate/validate into Luganda the Pelvic Floor Distress Inventory (PFDI-20) and

Pelvic Floor Impact Questionnaire (PFIQ-7) for Ugandan women of reproductive age in Kampala, Uganda.

This study will also examine risk factors for the development of PFD in this cohort, specifically examining

the associations between physical activity and the development of PFD, depression and the presence of PFD.
Uganda 2022-06-08 14:38:25 2025-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine  Ssirimuzaawo
ID:
Attention Deficit Hyperactive Disorder and Academic Achievement in Selected Government Primary schools in Wakiso District , Uganda.
REFNo: HS2282ES

1. To develop an ADHD model that will be used to address academic achievement in Government lower primary schools in Uganda, 2. To explain the role school related factors play in the academic achievement of children in selected Government primary schools in Wakiso District, 3. To find out if school related factors have an influence on ADHD symptoms in selected Government primary schools in Wakiso District., 4.To examine the effect of impulsive behavior on academic achievement of children in selected Government lower primary schools in Wakiso District Uganda and develop a model to explain that effect. 5.To assess the extent to which concentration level of learners affect their academic achievement of children in selected lower primary Government schools in Wakiso District,
Uganda 2022-06-06 11:42:14 2025-06-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Jane Fieldhouse
ID:
One Health Timeliness Metrics: Stakeholder Experiences in Multisectoral Outbreak Reporting
REFNo: HS2255ES

The general objective of this proposal is to evaluate timeliness, or speed of detection and response, during multisectoral outbreak events in Uganda. Quantitative and qualitative analyses of One Health timeliness metrics will be used to make recommendations for a One Health outbreak reporting tool designed to monitor progress toward finding and responding to outbreaks faster.
USA 2022-06-06 11:39:24 2025-06-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Lian Thomas Francessca
ID: UNCST-2022-R010668
Value chain based Taenia solium control in Northern Uganda (Research activity being applied for: Rapid value chain scoping)
REFNo: SS1296ES

The overall goal is to develop and trial a locally acceptable and appropriate value chain-based control program against T. solium codesigned through an inclusive participatory approach and tailored for the project area. Specifically, the project has the following objectives of which Objective 1 is the subject of this application. 1. Assess, describe, and map the pig value chain and the context for the control of T. solium in four districts (Kitgum, Pader, Lamwo and Agago districts) in Northern Uganda. 2. Conduct social network analysis to map movement of pigs within the districts to understand where they (farmers, traders, transporters, pork joint operators, butchers) get pigs and where most of the pigs are slaughtered to enable proper targeting of the interventions especially those targeting pork joints and consumers. 3. To utilize social network analysis and ‘net-mapping’ techniques to identify stakeholders essential in the control of T. solium and understand their relationships, power-dynamics, motivations 4. In a participatory manner with the stakeholders, identify best bet interventions to control Taenia solium and improve the value chain 5. To conduct an ex-ante impact assessment to understand the impacts of the proposed interventions 6. To implement a set of locally acceptable control strategies against Taenia solium infections targeted at various nodes of the pig value chain including market-based incentives to support uptake. 7. Conduct an ex-post impact assessment of the intervention in reducing the burden of Taenia solium infections and improving profitability of pig enterprises The current application is for activities under objective 1 (Assess, describe, and map the pig value chain in four districts (Kitgum, Pader, Lamwo and Agago districts) in Northern Uganda). For the subsequent activities we will be making separate applications or amendments and attaching the necessary documents.
UK 2022-06-06 11:37:58 2025-06-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Alice  Emasu
ID: UNCST-2021-R013920
Profiles of patients with obstetric fistula and childbirth related morbidities in Uganda
REFNo: HS2114ES

Examine the clinical characteristics of childbirth injuries in this group of women and determine the distribution of injuries: obstetric fistula, perineal tears, or pelvic organExamine the clinical characteristics of childbirth injuries in this group of women and determine the distribution of injuries: obstetric fistula, perineal tears, or pelvic organ prolapse, or other morbidities.Determine the demographic characteristics of those birth-injured women from the selected regions of UgandaExamine the four delays as experienced by those birth-injured women from the selected regions of Uganda.
Uganda 2022-06-06 10:27:48 2025-06-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Carolyn Nakisige
ID: UNCST-2021-R012699
PREVENTION AND SCREENING INNOVATION PROJECT TOWARDS ELIMINATION OF CERVICAL CANCER
REFNo: HS2222ES

1. To measure cost-effectiveness of the enhanced screening protocol programme,1. To evaluate if artificial intelligence offers the healthcare worker (HCW) reliable management decision support in the interpretation of cervical lesions during screening with visual inspection with acetic acid.,1. To evaluate the impact of the enhanced screening module on the uptake and coverage of cervical cancer screening and on the uptake of early treatment of precancerous lesions in the target area,1. To measure health system related factors for availability and quality of the health system for the enhanced cervical screening programme (including hrHPV testing and AI-DSS systems).,1.1. To measure, client related factors for accessibility, acceptability as well as adherence to the enhanced cervical cancer screening programme among the target population eligible for cervical cancer screening,The overall objective of the PRESCRIP-TEC project is to enrich existing cervical cancer screening programmes with women-friendly and cost-effective tools, and test in field conditions whether and why they are effective in increasing participation in cervical cancer screening in vulnerable groups in Central and Eastern Europe and in low- and middle-income countries (LMICs). ,
Uganda 2022-06-06 10:26:06 2025-06-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank Muhereza Emmanuel
ID:
Uganda Livelihood Coping Strategies and Severity Ranking, 2022.
REFNo: SS1298ES

This study aims to identify LCS that best signal stressed, crisis, emergency, and catastrophe levels of acute food insecurity (IPC Phases 2–5) among households in the Uganda RFZ and the livelihood zone clusters in it. These ranked lists will be used to inform the full resilience module of forthcoming USAID-supported resilience and food security assessments in Uganda.
Uganda 2022-06-01 17:29:05 2025-06-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ponsiano Ocama
ID: UNCST-2019-R000440
Clinical responses and novel biomarkers of antiviral treatment for prevention of HBV- and HBV/HIV-associated hepatocellular carcinoma
REFNo: HS1782ES

1. To define the response to HBV antiviral treatment in terms of standard and novel viral biomarkers and stabilization or regression of liver fibrosis among HBV mono-infected and HBV/HIV coinfected persons.
2. To identify clinical and viral factors associated with break-through HCC despite guideline appropriate HBV treatment and HCC surveillance, and evaluate if HCC stage at presentation or survival is moderated.
3. To assess the human serum albumin (HSA) adductome biomarker profile and dosimetry associated with HBV treatment need and with ‘functional cure’ in response to HBV antiviral treatment among HBV mono-infected and HBV/HIV coinfected persons.

Uganda 2022-05-31 10:36:39 2025-05-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Holly Koogler
ID:
Social Relationships and Child Labor Migration from Karamoja, Uganda: An Exploratory Study
REFNo: SS1302ES

•Investigate the social risk factors related to child labor migration •Explore the nuances of the social lives of child labor migrants, including both strengths and negative aspects of social relationships •Propose policies and potential interventions that reflect the true structure and dynamics of social networks for preventing child labor migration, mitigating the most dangerous forms, and withdrawing migrant children from labor
USA 2022-05-30 17:20:41 2025-05-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
ALICE GITAU WANGARI
ID:
FACTORS ASSOCIATED WITH CUMULATIVE INCIDENCE OF GESTATIONAL RHINITIS, AND ITS EFFECTS ON QUALITY OF LIFE AMONG MOTHERS ATTENDING MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS2239ES

1.To determine the cumulative incidence of gestational rhinitis in Mbarara Regional Referral Hospital
2.To determine the factors associated with gestational rhinitis among mothers attending Mbarara Regional Referral Hospital
3.To assess the quality of life among mothers with symptoms of gestational rhinitis attending Mbarara Regional Referral Hospital

Kenya 2022-05-30 17:17:54 2025-05-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Ahamya William
ID:
A Framework to Enhance Confidentiality and Privacy of Data in Motion.
REFNo: SIR102ES

Carryout a preliminary study to measure the effectiveness and efficiency of the designed framework.,To design a framework aimed at enhancing confidentiality and privacy of data in motion,To find out the weaknesses in the existing frameworks and establish requirements to improve the confidentiality and privacy of data in motion.,The main objective of this study will be to improve the existing frameworks by designing one with enhanced confidentiality and privacy of data in motion in car sensors.,
Uganda 2022-05-30 17:16:31 2025-05-30 Engineering and Technology Non-Clinical Trial Degree Award
George Mpanga Lutwama
ID:
Ugandan Veterans and the First World War
REFNo: SS1209ES

To identify the names of Ugandans who fought and died during the First World War.
Uganda 2022-05-30 17:14:58 2025-05-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kizito Muwonge
ID: UNCST-2022-R011250
Methicillin Resistant Staphylococcus aureus Carriage among selected livestock species in designated Districts in Uganda
REFNo: A187ES

1. Determine the burden of MRSA in cattle, goats, sheep and swine in the study districts
2. Determine the burden of MRSA in high - risk human categories in the study districts
3. Determine the knowledge, attitudes and practices of antimicrobial users towards antimicrobial resistance in the study districts
Uganda 2022-05-30 17:14:03 2025-05-30 Agricultural Sciences Non-Clinical Trial Degree Award
Joshua Muhumuza
ID:
Effect of chewing gum on duration of postoperative ileus following laparotomy for gastroduodenal perforations; a multi centre study.
REFNo: HS1665ES

i. To compare the time taken for post-operative ileus to resolve in the two groups. ii. To compare the duration of hospital stay in the two groups. iii. To determine other factors associated with the duration of post-operative ileus in the study population.
Uganda 2022-05-30 17:10:09 2025-05-30 Medical and Health Sciences Clinical Trial Degree Award
JUSTUS KIRABIRA
ID:
ASSOCIATION BETWEEN HIV SEROSTATUS AND PREMALIGNANT CERVICAL LESIONS AMONG WOMEN ATTENDING CERVICAL CANCER SCREENING CLINIC AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS2258ES

1. To determine the prevalence of HIV among women attending cervical cancer screening Clinic at MRRH
2. To determine the prevalence of premalignant cervical lesions among HIV positive and HIV negative women attending cervical cancer screening Clinic at MRRH
3. To establish the association between HIV and premalignant cervical lesions among women attending cervical cancer screening Clinic at MRRH.

Uganda 2022-05-27 19:02:21 2025-05-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Rukiya salim Abdillahi
ID:
Prevalence, clinical manifestations of pregnancy dermatoses and their effect on quality of life among women attending MRRH
REFNo: HS2238ES

To establish the prevalence of pregnancy dermatoses among women attending ANC clinic at MRRH.

To describe the clinical manifestations of pregnancy dermatoses among women attending ANC clinic at MRRH.
To assess the effect of pregnancy dermatoses on the quality of life of women attending ANC clinic at MRRH.

Kenya 2022-05-27 18:57:18 2025-05-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
African Surgical Outcomes Study in Paediatric patients (ASOS-Paeds)
REFNo: HS2179ES

In paediatric surgical patients < 18 years in Africa: To determine the association between pre-operative, intra-operative and facility factors with postoperative complications and death. ,In paediatric surgical patients < 18 years in Africa: To determine the incidence of intraoperative severe critical incidents,,In paediatric surgical patients < 18 years in Africa: To determine the in-hospital postoperative mortality rate up to 30 days post-surgery,,To determine the incidence of in-hospital postoperative complications up to 30 days post-surgery in paediatric surgical patients <18 years in Africa,
UK 2022-05-27 18:55:24 2025-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel  Arinaitwe
ID: UNCST-2021-R011754
Measuring imported infections and contributions to local transmission in Uganda and Zimbabwe: Uganda studies
REFNo: HS2048ES

To quantify and characterize imported malaria infections in two border sites in sub-Saharan Africa.

To determine the impact of importation on local transmission and identify appropriate targeted interventions in two border sites in sub-Saharan Africa

Uganda 2022-05-27 18:52:11 2025-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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