Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Nanfuka Kalule
ID:
MENTAL RESILIENCE IN THE FACE OF ANXIETY, DEPRESSION AND SUICIDAL IDEATION: A QUALITATIVE STUDY OF ADOLESCENTS LIVING WITH HIV IN UGANDA
REFNo: SS1307ES

Study Purpose
The study will examine mental resilience among ALHIV in Uganda in regard to how they manage psychosocial risk posed by anxiety, depression and suicidal ideation to realise what they consider a normal and full life for adolescents within their socio-cultural settings.

Specific objectives
1.To explore ALHIV’s conceptualisations of a normal and full adolescence within their socio-cultural settings.

2.To examine the psychosocial constraints that suffering from anxiety and/or, depression and suicidal ideation pose to the realisation of a normal and full life as defined by ALHIV in Uganda.

3.To examine the protective factors that enable ALHIV in Uganda to manage the psychosocial risk posed by the mental health conditions of anxiety and/or depression and suicidal ideation to realise a normal and full life within their socio-cultural context.

Uganda 2022-06-15 18:46:25 2025-06-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
Clare Kaijabwango
ID:
NON-GOVERNMENT ORGANISATIONS’ AID-FUNDED PROJECTS AND VALUE FOR MONEY IN UGANDA
REFNo: SS1305ES

To assess how effective NGO aid-funded projects have been in Uganda;
ii) To establish how relevant NGO aid-funded projects have been in Uganda;
iii) To examine the cost of NGO aid-funded projects in Uganda;
iv.) To assess how efficient NGO aid-funded projects have been in Uganda.

Uganda 2022-06-15 18:44:15 2025-06-15 Social Science and Humanities Non-Clinical Trial Degree Award
BRENDA GATI MIREMBE
ID: UNCST-2021-R013390
A cohort for evaluation of open-label PrEP delivery and PrEP preferences among African women. Protocol version 1.0 dated 02 February 2022
REFNo: HS2274ES

1. Estimate HIV incidence using the recency testing on samples from women who screen out due to HIV infection, as well as assess HIV incidence prospectively in the cohort.

2. Assess the characteristics of women who initiate PrEP compared to those who do not initiate PrEP.

3. Evaluate young women’s preferences for attributes of long-acting formulations of PrEP, using a discrete choice experiment.

4. Assess the acceptability of a patient-facing PrEP decision support tool to provide young women more informed choice about PrEP options.
Uganda 2022-06-15 18:42:27 2025-06-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SSEMBATYA RENNY
ID:
Quasi Experimental Study to Determine the Association Between the Provision of Prenatal Ultrasound and Neonatal and Maternal Outcomes in Rural Uganda
REFNo: HS1994ES

1) To assess the relationship between US program at rural Health Centers in an LMIC rand the need for neonatal resuscitation in the form of bag-mask ventilation at delivery.
2) To determine the relationship between an US program at rural Health Centers in an LMIC setting and the number of maternal hemorrhage cases.
3) To estimate the effect of an obstetric US program in a rural LMIC setting on stillbirth, neonatal mortality and maternal death within the first 28 days post-delivery.
4) To determine the relationship between an US program and referral and management decisions at rural Health Centers in an LMIC setting.
5) To compare the effect of an US program in the rural LMIC setting with the effect in a refugee camp setting.

Uganda 2022-06-15 18:39:46 2025-06-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kyazze Richard
ID:
Family Support Systems as Predictors for Alcohol Addiction Recovery Status in Uganda. A case of selected treatment facilities in Kampala and Wakiso Districts
REFNo: SS1281ES

1. To analyses the influence of family subsystems on alcohol addiction recovery among the relapse( case) and non- relapse (control) individuals in Kampala and Wakiso Districts Uganda.
2. To assess the effects of family communication on the alcohol addiction recovery status among the relapse (case) and non- relapse ( control) individuals in Kampala and Wakiso Districts Uganda.
3. To evaluate the mediating effect of recovery factors on family support systems and the alcohol addiction recovery status among individuals form the selected treatment facilities in Kampala and Wakiso Districts Uganda
Uganda 2022-06-14 15:11:17 2025-06-14 Social Science and Humanities Non-Clinical Trial Degree Award
Kizito Ndegeya
ID:
DETERMINANTS OF HOUSEHOLD FOOD SECURITY AND NUTRITIONAL STATUS OF CHILDREN AGED 24-59 MONTHS IN NAMUTUMBA DISTRICT
REFNo: HS2088ES

Main objective: Evaluate the relationship between household food security and nutritional status of children aged 24-29 months. Specific objectives: 1. Establish factors that affect food security status of households with children aged 24-59 months. 2. Assess the nutritional status of children aged 24-59 months. 3. Measure food security situation of households with children aged 24-59 months. 4. Determine the dietary diversity of children aged 24-59 months. 5. To assess the determinants of household food security and nutritional status of children aged 24-59 months in Namutumba District.,
Uganda 2022-06-14 11:29:47 2025-06-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Lynn Atuyambe Atuyambe
ID: UNCST-2021-R012602
DATA QUALITY ASSESSMENTS OF POST-ABORTION CARE RECORDS ACROSS 80 HEALTH FACILITIES IN UGANDA
REFNo: HS2260ES

GENERAL OBJECTIVE
To determine the data quality of post-abortion care records across randomly selected public health facilities in Uganda. This will help identify gaps to improve upon, as a means towards improving the quality of data and enable health planners develop appropriate interventions for improving womens health in Uganda.

Specific objectives

1. To determine the timeliness, accuracy, and completeness of post-abortion care data recorded across health facilities in Uganda.

2. To explore the roles and or perceptions of different stake holders in the quality of PAC data collected, synthesized and analysed at different levels in the health management information system.


Uganda 2022-06-14 11:16:46 2025-06-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizabeth Ekirapa
ID: UNCST-2020-R014390
MID TERM EVALUATION OF THE UGANDA HEALTH FINANCING STRATEGY (2015/16 -2024/25)
REFNo: HS2256ES

1. To track the progress of the implementation of the Uganda’s Health Financing Strategy 2015/16 -2024/25.
2. To identify bottlenecks hampering the implementation of Uganda’s Health Financing Strategy 2015/16 -2024/25.
3. To produce an addendum to Uganda’s Health Financing Strategy 2015/16 -2024/25 aimed at aligning the proposed interventions to the policy objectives of the NDP III, HSDP II and UHC Roadmap hence accelerating progress towards implementation of the recommendations outlined in the Health Financing Strategy 2015/16 -2024/25.
4. To develop an updated implementation plan/ Monitoring and Evaluation framework for Uganda’s Health Financing Strategy 2015/16 -2024/25 with detailed activities, related timelines and clear roles and responsibilities.
5. To update the health financing progress matrix for Uganda

Uganda 2022-06-14 11:07:50 2025-06-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Semitala Fred
ID: UNCST-2020-R014202
One-month of rifapentine-isoniazid (1HP) versus three-months of rifapentine-isoniazid (3HP) for tuberculosis prevention: preferences of people living with HIV in Kampala, Uganda
REFNo: HS2261ES

To understand preferences for current short-course TPT regimens (1HP vs. 3HP) among PLHIV receiving care at the Mulago Immune Suppression Syndrome (ISS) Clinic


To determine comparative preferences for attributes of future TPT regimens among PLHIV receiving care at the Mulago Immune Suppression Syndrome (ISS) Clinic.

Uganda 2022-06-14 11:05:00 2025-06-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violette Nabatte Nabatte
ID:
Prevalence of depression among adolescents living with HIV in care at Mildmay Uganda Hospital
REFNo: HS2289ES

1.To determine the prevalence of depression among adolescents living with HIV in care at Mildmay Uganda Hospital
2. To determine the factors associated with depression among adolescents living with HIV in care at Mildmay Uganda Hospital
Uganda 2022-06-14 10:48:53 2025-06-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Ngendo-Tshimba
ID:
Urban Refugees in Uganda: A rapid field-based study
REFNo: SS1309ES

The overarching objective of this study is to assess the widespread assumptions that the urban refugees are more self-reliant in Uganda than those who remain in rural-based refugee settlements.
Uganda 2022-06-14 10:41:23 2025-06-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sam Ononge
ID: UNCST-2020-R000328
Congo Red Test – Reducing Preeclampsia Morbidity and Mortality through Clinical Protocols Incorporating the Urine based Test
REFNo: HS2246ES

3) Map current diagnosis and care practices and referral patterns for the management of patients with suspected preeclampsia in order to better understand the impact of introducing the Congo Red Test in health services in the two countries.,2) Document the feasibility and acceptability to perform and interpret the CRD POC diagnostic test by health workers at selected health facilities. ,1) Describe the prevalence of urine congophilia among patients presenting for antenatal care and/or rule-out of suspected preeclampsia in selected health facilities.,Pilot study to test Identification of urine congophilia using the Congo Red Test will be acceptable and feasible for use in routine antenatal care services in Ethiopia and Uganda. ,
Uganda 2022-06-14 10:38:49 2025-06-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Racheal Ayanga Aida
ID:
Knowledge and access of sexual and reproductive health services for deaf adolescents in Uganda
REFNo: HS2250ES

1. To evaluate the sexual and reproductive health needs and knowledge for deaf adolescents through a community-based public health approach in Wakiso district, Uganda.
2.Determine the barriers to access of sexual and reproductive health services for deaf adolescents at government health facilities in Wakiso district, Uganda.
3. To seeking the opinions of community key informants on knowledge of and access of SRH services for deaf adolescents and how to improve knowledge and access of sexual and reproductive health services for deaf adolescents in Wakiso district.
Uganda 2022-06-14 10:35:34 2025-06-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eric Awich Ochen
ID: UNCST-2021-R013266
A Randomized Controlled Trial (RCT) Approach to Enhancing the Learning Experience for Pupils and Students in Schools in Kampala and Wakiso Districts, Uganda.
REFNo: SS1264ES

Study Purpose
The study aims at examining the effectiveness of school based social work in improving the safety of the learning environment, parental support and learner academic performance, psychosocial wellbeing and mental health in primary and secondary schools of Uganda

Specific Objectives
1. To examine the effectiveness of school based social work in reducing the experiences of VAC at home and school among learners in primary and secondary schools in Uganda
2. To examine the effectiveness of school based social work in increasing parental support towards the education of their children in primary and secondary schools of Uganda
3. To evaluate the effectiveness of school based social work in improving the psychosocial wellbeing of learners in primary and secondary schools of Uganda
4. To evaluate the effectiveness of school based social work in improving mental health outcomes among learners in primary and secondary schools of Uganda
5. To assess the effectiveness of school based social work in improving the academic performance of learners in primary and secondary schools of Uganda

Uganda 2022-06-13 15:24:18 2025-06-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Loic SEGALEN
ID: UNCST-2022-R011339
Uganda Palaeontology Expedition
REFNo: NS328ES

Study of the evolution of the past biodiversity (fossils), biostratigraphy and palaeoenvironments (palaeontology + geochemistry) during the Miocene and Pliocene (between 25 to 2.54 Million years ago) in Karamoja and in the West Nile. New fossils and field data are collected every year following standard field techniques during field surveys in association with the Palaeontogy Department of the Uganda Museum at Kampala
France 2022-06-13 15:22:39 2025-06-13 Natural Sciences Non-Clinical Trial Non-degree Award
Ben Lukubye
ID:
Epidemiological survey for Schistosoma hybrids in children in Packwach and Lango sub region, Uganda
REFNo: HS2284ES

To determine the prevalence, intensity and introgression of Schistosoma hybrids in children in Pakwach and Lango sub- region, Uganda ,
Uganda 2022-06-08 15:25:58 2025-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Adroma
ID: UNCST-2019-R000360
CLINICAL CHARACTERISTICS AND OUTCOMES OF COVID-19 INFECTED PREGNANT WOMEN ADMITTED AT ENTEBBE REGIONAL REFERRAL HOSPITAL COVID-19 TREATMENT UNIT IN UGANDA: A RETROSPECTIVE ANALYSIS
REFNo: HS2198ES

To describe the pregnancy and clinical outcomes of COVID-19 infected pregnant women admitted at Entebbe Regional Referral Hospital. ,To describe the clinical characteristics of COVID-19 infected pregnant women admitted at Entebbe Regional Referral Hospital. ,To investigate the clinical characteristics and outcomes of COVID-19 infected pregnant women admitted at Entebbe Regional Referral Hospital in Uganda.,
Uganda 2022-06-08 15:22:54 2025-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abdulwahab Sessolo
ID: UNCST-2021-R012752
Evaluation of the Tuberculosis Molecular Bacterial Load Assay (TB-MBLA) Research Use Only (RUO) Kit for the Diagnosis and Monitoring of Treatment Response using Sputum of Symptomatic Adult Patients with Pulmonary TB
REFNo: HS2265ES

To determine the performance of the TB-MBLA with reference to the standard of care tuberculosis (TB) tests for diagnosis and monitoring of pulmonary TB (PTB) in symptomatic adults when performed in high TB burden countries,Assessment of utility of the TB-MBLA web portal for presentation of the TB-MBLA results to the clinical and research staff. ,Evaluation if a TB-MBLA quantitative range that corresponds with sputum culture conversion can be determined,assessment of whether the changes in the bacteriological response to anti-TB treatment can predict treatment outcome.,Evaluation of the ability of TB-MBLA for measuring bacteriological response to anti-TB therapy in comparison with standard-of-care tests (MGIT culture, Xpert MTB/RIF assay and smear microscopy). ,Assessment of the clinical performance of TB-MBLA to detect TB in suspected disease by estimating accuracy parameters such as specificity and sensitivity,
Uganda 2022-06-08 15:17:44 2025-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ruth Mpirirwe
ID: UNCST-2022-R011229
Development, Feasibility and Preliminary Effectiveness of an HIV PrEP delivery model for improved adherence and retention to PrEP care among Female Sex workers in Uganda
REFNo: SS1223ES

i) To assess PrEP uptake and retention among female sex workers in the context of different PrEP models in Sub Saharan Africa
ii) To explore how current PrEP delivery models facilitate or hinder FSW initiation and continuation on PrEP care in Uganda
iii) To develop a PrEP delivery model that promotes adherence and retention in PrEP care among FSW in Uganda using a DCE
iv) To determine the feasibility and preliminary effectiveness of the DCE informed model in improving adherence and retention in PrEP care among FSW in Uganda
Uganda 2022-06-08 15:16:01 2025-06-08 Social Science and Humanities Non-Clinical Trial Degree Award
Linda Adiru Atiku
ID:
Knowledge, Attitudes, and Practices of Livestock Raisers Regarding Disposal of Anthrax-Suspect Carcasses in West Nile,Uganda.
REFNo: HS2091ES

1) To determine the knowledge, attitudes and practices (KAP) regarding livestock
carcass disposal for anthrax prevention among cattle/goat/sheep raisers in West
Nile region, Uganda
.. 2) To describe the existing animal anthrax carcass disposal methods in the West Nile region, Uganda
3) To develop recommendations to improve carcass disposal methods in the West Nile region, Uganda
Uganda 2022-06-08 15:14:19 2025-06-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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