Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Victor Musiime -
ID: UNCST-2021-R013794
 Building Resources to Assess Impaired Neurocognition in Children with HIV in Low and Middle Income Countries (BRAIN Child LMICs)
REFNo: HS2271ES

(1) Adapt NeuroScreen for Luganda-speaking children 5-12 years. (a) Through expert focus groups and multiple rounds of cognitive interviewing with children, determine necessary adaptations to make the NeuroScreen tests valid, acceptable and understandable to Luganda-speaking children, (b) implement
those adaptations in the app, (c) re-evaluate the adapted app with children, (d) examine its acceptability by clinical staff most likely to administer it, and (e) make further adaptations, as needed.

(2) Examine construct validity of the child version NeuroScreen tests. (a) Compare NeuroScreen test performance to gold standard neuropsychological test battery performance among Ugandan children 5-12 years with and without HIV, and (b) explore the relationship between performance on NeuroScreen and behavioral health.


 Uganda 2022-06-28 16:42:46 2025-06-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sophie Riddick
ID: UNCST-2022-R010576
 Decision-making and religious beliefs across cultures
REFNo: SS1336ES

study how children learn about religious beliefs and practices over development, gain an understanding of how children attend to normative information presented by a peer or by an adult
 UK 2022-06-28 14:39:43 2025-06-28 Social Science and Humanities Non-Clinical Trial Degree Award
ERICK SSEGUJJA
ID: UNCST-2021-R012964
 Donor transition and its effect on health coverage in Uganda
REFNo: HS2112ES

The aim of this study is to better understand how and why Uganda has (or not) been able to sustain effective coverage of health interventions after projects previously funded by donors ended and the enablers and barriers encountered in this,4. Identify health system adaptation strategies devised by (sub)national actors for sustaining coverage of the two selected interventions when donor projects ended from 2016-2017 to date.,3. Understand how the end of project funding affected the coverage of maternal health interventions and HIV services in case-study districts in 2016 and 2017 respectively.,2. Determine changes in (i) select maternal health indicators (ii) key HIV service indicators three years after the end of project funding between 2016 and 2017 in select donor- supported districts.,1. Explore the political, financing and health system factors that influenced whether coverage of maternal health interventions and HIV services were sustained once the projects funded by the donors ended between 2016 and 2017. ,
 Uganda 2022-06-27 8:45:40 2025-06-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 Implementation of Point of Care HIV Viral Load Monitoring to improve Viral Load Suppression among Children and Adolescents Living with HIV in East Africa.
REFNo: HS2025ES

14. Objectives of the research project:
Purpose: The purpose of EAPOC-VL project is to examine the feasibility, acceptability, and effectiveness of using point of care viral load (PoC VL) monitoring to improve viral load suppression among children and adolescents (age ?19 years) living with HIV in Kenya, Rwanda, Tanzania and Uganda.

Main Study Aims:
i) To determine the effectiveness of PoC VL monitoring in improving viral suppression among children and youth living with HIV in East Africa. ii) To evaluate feasibility and acceptability of using PoC VL monitoring among children and adolescents living with HIV in East Africa.

Objectives of Aim 1:
Primary objective
i. To estimate the effect of PoC VL monitoring on viral load suppression among children and adolescents living with HIV in East Africa at 6 and 12 months of followup.

Secondary objectives
i. To describe the effect of PoC VL monitoring on the proportion of children and adolescents living with HIV that experiences virological rebound after initial suppression within 6 and 12 months of follow-up.
ii. To describe the effect of PoC VL monitoring on time to initiation of intensive adherence counselling following virological failure among children and adolescents living with HIV.
iii. To estimate the effect of PoC VL monitoring on the proportion of children and adolescents living with HIV that experiences change of ART regimen within 6 and 12 months of follow-up.
iv. To determine the effect of PoC VL monitoring on the proportion of children and adolescents living with HIV that is retained in care at 6 and 12 months.

Objectives of Aim 2
i. To assess the acceptability of the implementation and scale-up of PoC VL testing and monitoring from the perspective of children, adolescents and their care givers. ii. To assess the critical determinants that may affect the implementation of PoC VL testing and monitoring from the perspective of healthcare workers and policy makers.
iii. To assess potential barriers and facilitators to implementation and scale-up of PoC VL testing and monitoring among children and adolescents living with HIV.
iv. To assess the incremental cost-effectiveness of PoC VL from a modified societal perspective using established models, with data collected alongside the implementation of the intervention combined with data estimated based on existing studies.

Uganda 2022-06-27 16:03:08 2025-06-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mercy Nwankwo Chinenye
ID:
DEVELOPING A MODEL FOR COMMUNITY RESILIENCE AND RAPID RESPONSE TO HEALTH CHALLENGES OCCASIONED BY ENVIRONMENTAL AND CLIMATE CHANGE DISASTER
REFNo: HS2267ES

i. Explore common environmental and climate change disasters and their effects in Kigezi regions and effects.
ii. Assess community and institutional level preparedness to address and mitigate the impacts of environmental disasters.
iii. Develop a community disaster response capacity to tackle any future environmental disasters in the Kigezi region.

 Nigeria 2022-06-27 15:51:51 2025-06-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Racheal Naturinda
ID:
UNDERSTANDING THE RURAL COMMUNITY BELIEFS AND BARRIERS AFFECTING IN THE MANAGEMENT OF SNAKEBITE ENVENOMING IN YUMBE DISTRICT.
REFNo: HS2243ES

The main objective of the study is to understand the community belief and barriers affecting the management of snakebite envenoming in Yumbe district. Specific objectives of the study 1. To determine the current prevalence of snake bite envenoming in Yumbe district. 2. To explore the community beliefs related to the management of snake bite envenoming in Yumbe district Northern Uganda. 3. To explore the barriers affecting management of snake bite envenoming in Yumbe Northern Uganda.
Uganda 2022-06-27 14:48:19 2025-06-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Ssekamatte
ID: UNCST-2022-R010961
 Exploring stakeholders’ views on integrating secondary distribution of HIV self-testing by FSW, pre-exposure prophylaxis (PrEP) starter packs, and enhanced handoffs to promote PrEP uptake and persistence among high-risk men in Kampala, Uganda. A qualitative study
REFNo: HS2154ES

1. Explore the awareness, willingness, barriers and facilitators to PrEP uptake and persistence among FSW and male clients
2. Elicit feedback on the concept of a combined intervention engaging FSW to reach their male clients with HIV testing self-testing and subsequent linkage to PrEP or ART uptake and persistence.

 Uganda 2022-06-23 10:37:33 2025-06-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Asega Pam Charles Aggrey
ID:
Factors influencing utilization of routine health information for decision making among health workers at health facilities in Moyo District, Uganda.
REFNo: HS2147ES

Broad Objective
The “broad objective of the study will be to establish the factors influencing utilization of routine health information for decision making among health workers” at health facilities in Moyo District, Uganda.
Specific Objective
The study will be guided by the following objectives:
i. To “determine the level of utilization of health information for decision making among health workers at health facilities in Moyo District, Uganda”
ii. To “establish the influence of technical factors among health workers on utilization of routine health information for decision making at health facilities” in Moyo District, Uganda.
iii. To assess the influence of organizational factors among health workers “on utilization of routine health information for decision making at health facilities” in Moyo District, Uganda
iv. To examine the influence of behavioral factors among health workers “on utilization of routine health information for decision making at health facilities” in Moyo District, Uganda.


Uganda 2022-06-23 10:34:58 2025-06-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Florence Ayebare
ID:
Health care seeking among people living with HIV and hypertension during the first and second wave of the COVID 19 pandemic in Uganda: A qualitative study of experiences, patterns of resort, facilitators and barriers in Wakiso district
REFNo: HS2186ES

• Explore health care provider experiences of service provision to PLHIV with Hypertension during the first two waves of the Covid-19 pandemic in Uganda,• Gain understanding of patterns of resort, decision making and priority setting for care seeking during the first two waves of COVID-19 in Uganda,• Explore health care seeking experiences of PLHIV with Hypertension during the first two waves of the COVID-19 pandemic in Uganda,
 Uganda 2022-06-23 10:33:20 2025-06-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BARIYANGA Jean Damascene
ID:
TOXIN GENE PROFILING AND ANTIBIOTIC SUSCEPTIBILITY OF Bacillus cereus ISOLATED FROM RAW BOVINE MILK SOLD WITHIN KAMPALA CAPITAL CITY
REFNo: NS356ES

i. To determine the prevalence of B. cereus in raw bovine milk from the Kampala district
ii. To determine the antibiotic susceptibility patterns of B. cereus isolated from raw bovine milk from the Kampala district
iii. To detect selected toxin encoding genes harboured by B. cereus isolated from raw bovine milk from the Kampala District.
 Rwanda 2022-06-22 12:14:52 2025-06-22 Natural Sciences Non-Clinical Trial Degree Award
Caroline Fryns
ID:
Infant-directed vocalizations in Chimpanzees (Pan troglodytes)
REFNo: NS272ES

There is clear evidence that surrounding and directed vocalizations have a part in the development of the vocal competence of infants. What part each input plays in vocal development is, however, unclear. As such, the overall aim of this study is to investigate further on the presence and the roles of the different vocal inputs available during the vocal development of wild eastern chimpanzees (Pan troglodytes schweinfurthii). More precisely, the study sets out to identify infant-directed vocalizations and characterize its acoustic and structural properties as well as investigate on its function in respect to ISV on the three different levels of vocal acquisition (see Table 1 for a summary of the hypotheses): production, comprehension and usage (Seyfarth & Cheney, 2010).

This study is part of a wider initiative which sets out to understand the evolution of human language and consequently the evolution of the learning mechanisms set in place in parallel throughout closely related species.
France 2022-06-22 12:11:58 2025-06-22 Natural Sciences Non-Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Establishment of Quality Assured COVID 19 Specimen Repository to Support Research in Diagnosis, Prevention and Management of SARS CoV 2 in Uganda
REFNo: HS869ES

(i) Establish a biobank of well-annotated and well-characterized samples of various types, collected from positive COVID -19 patients, asymptomatic SARS CoV-2 individuals and suspects.
(ii) Perform SARS CoV-2 full genome sequencing to support molecular epidemiology, track genetic/antigenic diversity in comparison with first sequences deposited in databases
(iii) Conduct performance evaluations of the Xpert Xpress SARS CoV-2 Rapid Diagnostic Test for adoption and adaptation in Uganda.
(iv) Conduct performance evaluations of the select serological assays for adoption and adaptation in Uganda.
(v) Detect SARS CoV-2 RNA in patientsā€™ stool and urine and evaluate their utility as surrogate specimens for COVID-19 diagnosis
(vi) Study select SARS CoV-2 protein and nucleic acid as prognostic markers for COVID-19 severity and or response to treatment.
(vii) Investigate the relationship between levels of BCG vaccine-specific immune responses on the risk of SARS CoV-2 Infection among high-risk individuals, on immune responses against SARS CoV-2 and clinical outcomes of COVID-19 patients.

 Uganda 2022-06-21 8:43:52 2025-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark-Donald Mwesiga Bikosa
ID:
Describing the Current State of Palliative Care in Uganda
REFNo: HS1874ES

ā—¸ Determine nationwide palliative care coverage through mapping the availability of basic palliative care services in Uganda;
ā—¸ Identify districts/areas without palliative care for targeted intervention;
ā—¸ Describe differences in palliative care services in: government vs. private; facilities; rural vs. urban settings; and different geographic locations throughout Uganda;
ā—¸ Make recommendations for continued scale up and integration of the mHealth surveillance system in collaboration with the Ministry of Health;
ā—¸ Make recommendations at the policy and programmatic levels to continue to enhance palliative care development in Uganda.

 Uganda 2022-06-20 8:31:29 2025-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Namusobya Sarah
ID:
Prevalence of chronic respiratory symptoms and chronic obstructive pulmonary disease among post-TB patients in Uganda.
REFNo: HS2232ES

3. To determine factors associated with chronic respiratory symptoms and COPD after successful PTB treatment.,2. To determine the prevalence of COPD among participants with chronic respiratory symptoms after successful PTB treatment.,1. To determine the prevalence of chronic respiratory symptoms after successful PTB treatment. ,
 Uganda 2022-06-20 8:25:00 2025-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Lubwama Ntege
ID:
Inspection Approaches and Teacher Instructional Effectiveness in Uganda Government-Aided Primary Schools:Case of Mukono District.
REFNo: SS697ES

To assess the relationship between the directive inspection approach and teacher instructional effectiveness in government-aided primary schools in Uganda.
To investigate the relationship between the non-directive inspection approach and teacher instructional effectiveness in government-aided primary schools in Uganda.
To establish the relationship between the collaborative inspection approach and teacher instructional effectiveness in government-aided primary schools in Uganda.
 Uganda 2022-06-20 8:16:09 2025-06-20 Social Science and Humanities Degree Award
Harriet Aber
ID:
Child and Adolescent Substance Use in Mbale district, Uganda: prevalence, help seeking, facility readiness and Acceptability of CRAFFT screening
REFNo: HS2182ES

To examine the prevalence of substance, use and help-seeking among children and adolescents, facility readiness and the acceptability of CRAFFT screening for child and adolescent substance use in Mbale district.
 Uganda 2022-06-20 11:04:14 2025-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
ROSCO KASUJJA
ID: UNCST-2019-R000504
 PlayMatters: formative study to gain insight in child-caregiver interactions at home to better understand possible opportunities to strengthen readiness to engage in learning through play.
REFNo: SS1272ES

The primary objective of this study is to explore and describe child-caregiver interactions with a focus on play, identify caregiver, household and community-level influences on child-caregiver interactions, and describe barriers and opportunities for supportive interactions that will positively influence the holistic development of children in this context.,
 Uganda 2022-06-16 17:35:39 2025-06-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Leonie Eva Benker
ID:
On the emergence of a "post-postcolonial" political imaginary in Uganda
REFNo: SS1282ES

MAIN OBJECTIVES 1. Gain deeper insights into the role that historical-political narratives play in political and social transformation processes, 2. Achieve a better understanding of the transformative potential of political movements in terms of their concrete strategies, practices, and (media) performances, 3. Determine the extent to which the new political forces and developments in Uganda might indicate the emergence of a fundamentally new social and political formation characterized by a move away from a postcolonial and toward a "post-postcolonial" societal self-conception and political imaginary. SPECIFIC OBJECTIVES a) Provide a comprehensive account of which historical-political narratives are currently being (re)produced and disseminated in the education sector and which alternative narratives might appear in this context and could be of relevance to A-level and university students. b) Describe how youths and young adults in Uganda today (re)interpret, (re)evaluate and (re)classify events of their country's political past and present and how they might aim to utilize and apply these altered / newly constructed historical-political narratives in and for the formation of their identities as political actors and citizens of the Ugandan nation-state. c) Delineate how these newly emerging historical-political narratives possibly differ from the hitherto dominant narratives and explain how they might seek to provide an alternative to the hitherto dominant historical-political stories and to the current political status quo.
 Germany 2022-06-16 14:44:52 2025-06-16 Social Science and Humanities Non-Clinical Trial Degree Award
Jennifer Parkinson
ID: UNCST-2022-R010888
 Exploring Human Origins in the Albertine Rift Valley, Uganda
REFNo: SS1257ES

This project will conduct paleoanthropological research in central Africa, at fossil sites located near the shores of Lake Albert in the western branch of the Rift in western Uganda (Albertine Rift). Our goal is to investigate the diversity of adaptive challenges faced by early human ancestors, in order to better understand the forces driving human evolution. We will document the distribution and age of sites, collect and describe new fossil and archaeological evidence, and re-examine previous collections in the Uganda Museum. Drawing on the team’s expertise in innovative approaches in archaeology, paleoecology, and geochronology, we aim to renew human origins research in this underexplored region.
 USA 2022-06-16 14:43:10 2025-06-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gumisirizah Nicholus
ID: UNCST-2021-R011816
 Effect of problem based learning on students' academic achievement in physics at lower secondary school level in Sheema District
REFNo: SS1304ES

To compare the improvement in students' academic achievement in physics after implementation of Problem based learning instruction and those with traditional approach
To assess the improvement in students' critical thinking skills developed after the implementation of problem based learning instruction and those traditional approach
To assess the improvement in problem solving skills developed after implementation of problem based learning and those with traditional approach
To determine variations in students' academic achievement in physics for government and private lower secondary schools in Sheema
 Uganda 2022-06-15 18:47:56 2025-06-15 Social Science and Humanities Non-Clinical Trial Degree Award
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