Joseph Baluku B
ID: UNCST-2019-R000612
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Mycobacterium tuberculosis infection and DNA damage in HIV-associated lung cancer in Uganda
REFNo: HS2328ES
STUDY AIM 1: To determine the association between Mycobacterium tuberculosis
infection and HIV-associated lung cancer in Uganda.
STUDY AIM 2: To compare the degree of DNA damage and methylation among people
with HIV-associated cancer with and without Mycobacterium tuberculosis infection.
SECONDARY AIM: To determine the effect of tuberculosis preventive therapy (TPT) on
the six-month survival of people with HIV-associated lung Cancer and LTBI in
Uganda
|
Uganda |
2022-07-18 14:31:31 |
2025-07-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Nelson Sewankambo K
ID: UNCST-2020-R014578
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Development and Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening (SIMCS)
REFNo: HS2333ES
1. To develop and evaluate a four module 3G or more cell phone app for a novel SCD screening information management and communication system (SIMCS)
2.To evaluate the impact of the SCD SIMCS on access to screening and care and outcomes of children with SCD.
|
Uganda |
2022-07-18 14:29:19 |
2025-07-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Andrew Obuku Ekii
ID: UNCST-2024-R002288
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IMMUNOLOGICAL AND VIROLOGICAL FACTORS ASSOCIATED WITH VIROLOGICAL CONTROL IN ACUTE AND EARLY HIV-I INFECTION.
REFNo: HS2264ES
• To characterize the earliest host factors associated with plasma viral load decline from peak viremia to viral setpoint.
a) To determine the functional and molecular profile of innate immune cells at each stage of acute and early HIV infection.
b) To determine the functional and molecular profile of adaptive immune cells at each stage of acute and early HIV-I infection.
c) To determine the impact of early cART treatment on:
l) Size of translational competent viral reservoirs
Il) Development of HIV specific immune responses
d) To determine HIV evolution in acute and early HIV1 infection
Specific objectives are:
1 . To determine the association of CD8 T cell subsets with plasma viral load and CD4 trajectories following acute and early HIV-I infection.
2. To determine the association of cell death mechanism with T cells following acute and early HIV-I infection.
3. To determine the viral replicative inhibitory properties of CD8 T cell subsets following acute and early HIV-I infection.
4. To determine the TCR and BCR of the cells with the highest viral inhibition potency.
5. Predict antigen that induced the TCR and BCR specificity in the cellular subsets with the highest viral inhibition potency.
6. To associate HIV specific B cell phenotypes with viremia in acute and early HIV infection.
7. To associate complement proteins with viremia and development of broadly neutralizing antibody in acute and early HIV-I infection.
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Uganda |
2022-07-18 14:27:23 |
2025-07-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Macdonald Isabel
ID:
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Do anonymous ratings build trust in mobile money agents? Evidence from Uganda
REFNo: SS1344ES
The goal of the research is to determine if mobile money users in Uganda trust anonymous customer ratings, and if these ratings would make users more willing to trust unknown agents. Furthermore, the research will explore the extent to which social stigmas restrict information sharing about agent trustworthiness.
Specific Objectives
Establish whether anonymous reviews increase trust, both in behavioral games and in unknown mobile money agents
Investigate if social stigmas restrict info sharing about agent trustworthiness
|
USA |
2022-07-15 15:59:49 |
2025-07-15 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Polycarp Omara
ID: UNCST-2022-R011110
|
CHILDREN’S EXPOSURE TO VIOLENCE IN REFUGEE EDUCATIONAL SETTINGS: MITIGATING THE EFFECTS ON EDUCATION AND SOCIAL WELLBEING IN WEST NILE, UGANDA
REFNo: SS1331ES
1. To analyse the various forms of VAC among the refugee children in Refugees Educational settings in West Nile.
2. To establish the common perpetrators of VAC in refugee education settings in West Nile.
3. To establish the effects of VAC in refugee education settings in West Nile.
4. To propose the strategies for preventing VACs in refugee education settings in West Nile.
|
Uganda |
2022-07-15 15:56:51 |
2025-07-15 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
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Performance evaluation of the Molbio Diagnostics Truenat™ MTB Plus/COVID-19 for TB and COVID-19 case detection using prospectively collected NP swabs and sputum samples from participants with symptoms suggestive of TB.
REFNo: HS2346ES
To assess the feasibility and ease of use of self-sampled tongue swab,To determine the prevalence of COVID-19 (by RT-PCR) among patients identified as having TB by MRS,To determine the prevalence of COVID-19 (by RT-PCR) among presumptive TB patients investigated for COVID-19,To determine the diagnostic accuracy of Truenat™ MTB Plus/COVID-19 multiplex for TB detection compared to GeneXpert Ultra among presumptive TB patients using a MRS,To determine the diagnostic accuracy of Truenat™ MTB Plus/COVID-19 for COVID-19 detection among presumptive TB patients using a country-approved RT-PCR COVID-19 assay,To determine the diagnostic accuracy of Truenat™ MTB Plus/COVID-19 multiplex for TB detection among presumptive TB patients using a Microbiological reference standard (MRS),
|
Uganda |
2022-07-14 12:36:25 |
2025-07-14 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Martin Hasselmann
ID:
|
The molecular mechanisms underlying local adaptation to high elevation habitats in the honey bee Apis mellifera
REFNo: NS350ES
The overall objective is to obtain a better understanding of the molecular mechanisms that have driven the local adaption of mountain honey bees.
The research plan is divided into a sequence of different complementary approaches that will
1.) Unravel the evolutionary history of chromosomal rearranged regions contributing to the genetic differentiation of mountain honeybees,
2.) Gain insight into key regulators and gene networks underlying the local adaption of honeybees,
3.) Specifically analyze the role of octopamine ? receptors and further candidate genes as key players for local adaptation to elevation (mainly temperature) in honey bees.
|
Germany |
2022-07-14 12:35:17 |
2025-07-14 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
Katungi Ninsiima Remmy Brian
ID:
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Assessment of Alternative Rites of Passage Interventions implemented by UNFPA/UNICEF Joint Programme on the Elimination of Female Genital Mutilation in Uganda
REFNo: SS1352ES
Specific objective 4: Assess the impact and sustainability of ARPs in fostering FGM abandonment and promoting egalitarian gender norms, attitudes, and behaviours among community members, by: a) assessing whether previous ARP cohorts have sustained any changes b) assessing whether communities who have undergone or are undergoing ARPs have the commitment and capacity to continue ARPs (rather than FGM) c)identifying lessons for replication/scaling up of ARP interventions (including, for example, what needs to be in place for particular ARPs to be implemented in future or in other contexts),Specific objective 3: Assess the effectiveness of ARPs in achieving positive outcomes, including: a) increasing girls’ knowledge of FGM-related issues including sexual and reproductive health, prevention of gender-based violence, and child marriage b) Promoting positive attitudes and behaviours among girls in relation to FGM and sexual and reproductive health, gender-based violence and child marriage. c) promoting social norm change within communities, including promoting egalitarian gender norms among girls, boys, parents, elders and community leaders,Specific objective 2: Assess the coherence (in terms of compatibility) of ARPs with other interventions to end FGM by implementing partners or other stakeholders in the geographical region, including by: a) identifying synergies and interlinkages between ARPs and other interventions to end FGM that are either carried out within or are expected to affect the same communities b) analysing the extent to which other interventions (including, for example, policy advocacy) support or undermine ARPs, and vice versa c )assess the consistency of the intervention with other interventions in/affecting the same contexts, including coordination with others, and the extent to which the intervention is adding value while avoiding duplication of effort,Specific objective 1: Assess the relevance of ARPs to the aim of eliminating FGM, by: a) describing the context of ARP interventions, with specific attention paid to the significance and symbolic meaning within communities of girls’ initiation rites or coming of age ceremonies b) identifying the intervention models (operating structure and procedures) of ARPs, and the roles of various community institutions and actors (such as parents, and religious and community leaders) engaged in ARPs c) analyzing if (and why/why not) specific ARPs meet community needs and are a relevant approach to include in programming to eliminate FGM d) analyzing the extent to which framing interventions as an ARP bring added value, over and above delivering the intervention under non-ARP rubric (including, for example, exploring whether framing life skills courses with graduation ceremonies as ARPs brings added value, or whether it introduces extra risk of the intervention being rejected),The primary objective of this evaluation is to provide an assessment of whether ARPs ‘work’ has been successful in promoting FGM abandonment, based on evidence of their relevance, coherence, effectiveness, impact and sustainability.,
|
Uganda |
2022-07-13 17:13:28 |
2025-07-13 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Moffat Nyirenda Joha
ID: UNCST-2020-R019333
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Development and Evaluation of an Integrated Community-based Management Model for HIV, Diabetes, and Hypertension in Tanzania and Uganda (The INTE-COMM study)
REFNo: HS2278ES
To determine the effectiveness of community-based integrated management of HIV, diabetes, and hypertension in comparison to clinic-based integrated management of these conditions in terms of patient outcomes, acceptability, and potential cost-effectiveness.
|
Malawi |
2022-07-13 16:33:33 |
2025-07-13 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Jackson Mukonzo
ID: UNCST-2021-R013916
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Ivermectin-artemisinin Combination Therapy for Eradication of Malaria
REFNo: HS2081ES
Main Objective:
1. To investigate the effect of ivermectin adjunct therapy on household transmissibility of malaria from malaria-infected patients receiving artemether /lumefantrine
Specific objectives
1. To determine the household malaria transmissibility within one month of IVN and
artemether / lumefantrine therapy.
2. To determine the structural similarity of the nanopore plasmodium sequences between
infecting plasmodium species isolated from the index patient and other household malaria
positive patients.
3. To assess the safety of ivermectin-artemether/lumefantrine in malaria-infected patients.
|
Uganda |
2022-07-13 16:29:55 |
2025-07-13 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Eleanor Brown Lucy
ID:
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A sex and gender-based analysis of access to Vitamin A programmes in four sites in Uganda
REFNo: HS2320ES
The overall objective of the SGBA is to identify gender inequalities and inequities, as well as associated barriers and needs, which affect access and uptake of Vitamin A supplementation programmes. The SGBA will also identify strengths and opportunities and provide recommendations to make VAS programmes more gender responsive.
1. To identify the gender equality issues that influence access to preventative health and nutrition services for child survival, and the quality of services provided.
2. To assess the level of gender mainstreaming in the design of preventative health nutrition services for child survival such as VAS, their implementation and MEAL system and indicators.
3. To identify potential opportunities and enablers and provide recommendations to increase the level of gender responsiveness in preventative health and nutrition services for child survival programming models such as the VAS programme.
4. To explore how COVID-19 affected access to and use of preventative health and nutrition services for child survival programme areas, including VAS programmes, and to provide recommendations for gender-sensitive support to both programme beneficiaries and key services providers and promoters at health facility and community levels.
|
UK |
2022-07-13 10:48:27 |
2025-07-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
|
Translation and validation of the Perinatal Grief Intensity Scale in Kenya and Uganda
REFNo: HS2296ES
1. To perform a culturally sensitive translation and adaptation of the Perinatal Grief Intensity Scale in Kiswahili and Luganda
2. To assess validity and reliability via face, content and construct validity and internal consistency
3. To obtain statistical estimates pertaining to the use of the tool
|
Uganda |
2022-07-13 10:47:29 |
2025-07-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Mohammed Lamorde
ID: UNCST-2019-R001293
|
Sentinel Surveillance of Acute Febrile Illness (AFI) in Regional Referral and District Hospitals in Uganda
REFNo: HS2277ES
Identify etiologies and define the epidemiology of AFI among children, adolescents and adults attending referral hospitals in Uganda.
Build and strengthen sustainable surveillance, laboratory, and information systems to improve epidemic intelligence across multiple priority outbreak-prone febrile illness in Uganda.
|
Nigeria |
2022-07-13 10:45:57 |
2025-07-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Maureen Sylvia Kusiima
ID:
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Multisectoral maternal and child healthcare financing in Uganda
REFNo: SS1355ES
To develop a multisectoral MCH financing policy framework that can enable adequate funding for MCH programmes and interventions aimed at improving the MCH services and reducing maternal and child mortality by 2030.,To analyse the major determinants of enrolment of women and children for CBHIs to enable policymakers to adopt the best strategies for increasing enrolment and raise adequate MCH funds. ,To examine the relationship between Uganda’s healthcare financing strategy and access to MCH services that will inform decision making in MCH financing in Uganda.,To explore international best practices regarding multisectoral MCH financing strategies to gain knowledge and inform the development of a multisectoral MCH financing policy framework for Uganda.,
|
Uganda |
2022-07-13 10:42:17 |
2025-07-13 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Moses Joloba
ID:
|
Improving the TB/HIV Clinic-Laboratory Interface in Uganda
REFNo: HS2162ES
The overall goals of this project include: (1) Improve TB case finding and TB treatment among eligible persons in Uganda (2) Improve time-to-TB diagnosis and time-to-TB therapy or treatment initiation among HIV-positive and HIV-negative persons with presumptive or confirmed TB in Uganda.
To achieve the above goals, CLICQ! – ECHO implementation has four major objectives:
1. LAB TESTING SERVICES
Increase the number and proportion of HIV-positive and HIV-negative persons with presumptive TB that receive TB laboratory testing services and/or accurate test results in a timely manner.
2. INITIATE APPROPRIATE TREATMENT
Increase the number and proportion of HIV-positive and HIV-negative TB patients that initiate appropriate (drug-sensitive or drug-resistant) TB treatment.
3. TURNAROUND TIMES
Reduce turnaround times associated with TB laboratory receipt of specimens for testing, lab-confirmation of TB disease, and return of TB laboratory test results and/ or initiation of appropriate TB therapy.
4. DiCE ASSESSMENTS ALONE VERSUS DiCE ASSESSMENTS WITH CQI TRAINING
Quantify the value of providing sites DiCE assessments alone versus providing sites DiCE assessments plus 2 learning sessions that are strengthened with weekly, ECHO-based, mentorship as well as ad hoc consultations via WhatsApp.
|
Uganda |
2022-07-13 10:41:00 |
2025-07-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Judith Owokuhaisa
ID: UNCST-2022-R011528
|
Transfer of care from hospital to outpatient and community settings for older people with diabetes mellitus/hypertension( DM/HTN) in south western Uganda
REFNo: HS2304ES
To explore experiences of older people with DM/HTN and their caregivers about transition of care to the community and self-management of health problems after discharge.,To explore the barriers and facilitators to discharge planning and transition of care for older people with DM/HTN.,General objective To describe the transfer of care from hospital to outpatient and community settings for older people with diabetes mellitus/ hypertension( DM/HTN) in south western Uganda.,
|
Uganda |
2022-07-12 12:37:00 |
2025-07-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Robert Opiro
ID:
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Exploration of Simulium microbiomes as a novel vector control-based approach against Onchocerciasis
REFNo: HS2291ES
4. Determine the Onchocerca infection status of S. damnosum s.l. in northern Uganda and, if possible, correlate this with microbiome structure,3. Determine S. damnosum s.l. microbiomes for symbionts of potential value in biological vector control,2. Quantify the extent of variation in adult S. damnosum s.l. microbiomes and the determinants of this variation,1. Determine the gut microbiome of adult Simulium damnosum sensu lato (s.l.), the most abundant vector of O. volvulus in northern Uganda,To generate baseline data for further important and therefore eminently fundable research on exploration of innovative Simulium-borne disease-control strategies aimed to reduce vectorial capacity and/or inhibiting pathogen transmission,
|
Uganda |
2022-07-12 12:33:56 |
2025-07-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
MATTHEW TUMUSIIME TUGUME
ID:
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PREVALENCE AND FACTORS ASSOCIATED WITH INFERTILITY AMONG WOMEN ATTENDING GYNECOLOGY OUTPATIENT DEPARTMENT AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1365ES
1) To establish the prevalence of infertility among women attending gynecology outpatient department at MRRH.
2) To identify factors associated with infertility among women attending gynecology outpatient department at MRRH.
|
Uganda |
2022-07-12 12:32:19 |
2025-07-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Monica Swahn H
ID: UNCST-2021-R012004
|
The Onward Project On Well-being and Adversity (“TOPOWA”): Focus Groups and Photovoice
REFNo: SS1347ES
To identify AGYW’s perceptions of proximal social and environmental stressors and their role in mental health outcomes. This study will focus on answering this objective focus groups discussions and the Photovoice to collect perspectives of AGYW who are 18-24 years and older.
|
USA |
2022-07-12 12:31:26 |
2025-07-12 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
MOSES KALANZI
ID:
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Assessing drowning prevention Interventions in Uganda. Baseline survey of landing sites in Mayuge District on L. Victoria
REFNo: SS1349ES
Main Objective;
To assess drowning prevention interventions on landing sites in Mayuge Districts
Specific objectives of the study include:
To assess community knowledge, attitude and beliefs on drowning and drowning prevention interventions
To equip youth in Mayuge with water safety and survival swimming skills
To impact drowning prevention on the national and international level through research and dissemination
|
Uganda |
2022-07-12 12:30:22 |
2025-07-12 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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