Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
SIMON ARUNGA
ID: UNCST-2021-R013498
 CAPACITY OF THE HEALTH SYSTEM IN MANAGEMENT OF GLAUCOMA IN SOUTHWESTERN UGANDA.
REFNo: HS2016ES

4. Explore the health provider-based barriers for glaucoma screening and treatment in Southwestern Uganda.,3. Describe the capacity of managing glaucoma at the regional referral hospitals in Southwestern Uganda.,2. Describe the capacity for glaucoma screening at the primary health centres in Southwestern Uganda.,1. Determine the proportion of glaucoma among patients presenting to primary health centres in Southwestern Uganda.,Conduct a baseline assessment to describe the capacity of the health system to manage glaucoma.,
 Uganda 2022-02-03 2025-02-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WILBROAD ARYATWIJUKA
ID:
Supply chain efficiency of relief operations in Uganda
REFNo: SS1037ES

To examine the relationship between stakeholder competencies and supply chain efficiency of relief aid organizations in Uganda.,To determine the mechanisms of improving supply chain efficiency of relief operations in Uganda during the crisis.,To examine the challenges of relief operations during covid19 pandemic Uganda.,To establish the factors that affect supply chain efficiency of relief operations in Uganda.,
 Uganda 2022-02-01 2025-02-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Emmy Okello
ID: UNCST-2020-R009792
 Remote Ischaemic Conditioning in STEMI patients in sub-Saharan AFRICA: The RIC-AFRICA trial
REFNo: HS1865ES

RIC will reduce the rates of all-cause death and early post-myocardial heart failure by approximately 25% when compared to sham control.,The RIC-AFRICA trial will investigate the effect of RIC in STEMI patients on the rates of all-cause death and early post-MI heart failure (pre-discharge HF and hospitalisation for HF at 30 days post-MI,) when compared to sham control,
 Uganda 2022-02-01 2025-02-01 Medical and Health Sciences Clinical Trial Non-degree Award
Lindrio Celestine
ID:
Alcohol Addiction and Recovery Interventions:A Case of Selected Rehabilitation Centers in Wakiso and Kampala Districts, Uganda.
REFNo: SS1026ES

1.To analyze the effect of alcohol addiction on recovery interventions used at Butabika and Serenity rehabilitation centers in Wakiso and Kampala districts, Uganda. 2.To examine the influence of alcohol addiction on recovery interventions at Butabika and Serenity rehabilitation centers in Wakiso and Kampala districts, Uganda. 3.To evaluate the effect of recovery interventions on alcohol addiction at Butabika and Serenity rehabilitation centers in Wakiso and Kampala districts, Uganda. 4.To establish the relationship between alcohol addiction and recovery interventions at Butabika and Serenity rehabilitation centers in Wakiso and Kampala districts, Uganda. 5.To develop a model that will help to address alcohol addiction in the rehabilitation centers in Uganda.
Uganda 2022-02-01 2025-02-01 Social Science and Humanities Non-Clinical Trial Degree Award
Rosta Asiimwe
ID:
IMPACT OF BLENDED LEARNING ON ACADEMIC PERFORMANCE IN EARLY CHILDHOOD EDUCATION IN UGANDA (A CASE STUDY OF PEAK KINDERGARTEN)
REFNo: SS1051ES

The purpose of this research is to determine the impact of blended learning on Kindergarten children’s academic performance, describe modifications in instructional strategies made by teachers to achieve the intended learning objectives and to document parents perceptions towards online learning during the COVID 19 pandemic.
 Uganda 2022-02-01 2025-02-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jonathan Kayondo
ID: UNCST-2021-R008325
 Target Malaria Protocol B1: Insectary facility readiness establishment of wild type and colour variant An. gambiae colonies in the ACL2 insectary, human capacity developments and support to field entomology, stakeholder engagement and regulatory activities
REFNo: HS1888ES

1. Establish and maintain a wild type An. gambiae colony in the ACL2 insectary. 2. Importing and/or local creation and maintaining of color variant mosquitoes. 3. Support to Field Entomology, stake holder engagement and Regulatory activities 4. Human capacity developments.
Uganda 2022-02-01 2025-02-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
REBECCA CLAIRE LUSOBYA
ID:
THE PERFOMANCE AND ACCEPTABILITY OF A LOW-COST ANTERIOR EYE EXAMINATION LOUPE (ARCLIGHT) COMPARED TO THE PORTABLE SLIT LAMP IN THE DIAGNOSIS OF ANTERIOR EYE DISEASES.
REFNo: HS2007ES

1. To assess the performance of the Arclight device in comparison to the portable slit lamp in assessing anterior eye diseases by primary eye care workers.
2. To determine the acceptability of using Arclight medical device in diagnosis of common anterior eye diseases.

Uganda 2022-02-01 2025-02-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 ‘STANDARD Q Syphilis Ab Test’ (Sample type comparison and part of the diagnostic sensitivity & diagnostic specificity)
REFNo: HS2039ES

- to establish the clinical performance of the STANDARD Q Syphilis Ab Test in accordance with the requirements of the Technical Specifications Series (TSS) for submission to WHO Prequalification – Diagnostic Assessment: TSS-6.,- to demonstrate the equivalence of serum, plasma (EDTA-K2), venous whole blood (EDTA-K2) and capillary (fingerpick) whole blood on the STANDARD Q Syphilis Ab Test.,
 Uganda 2022-02-01 2025-02-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrea Guariso
ID:
Bridging the Research-Policy Gap on COVID-19
REFNo: SS1069ES

Overall, with this project we seek to provide a mapping of the research that has been done on COVID-19, as well as to examine the relationship between researchers and decision-makers during this period with the goal of informing efforts to strengthen ties between research and policy in the future.
 Italy 2022-01-28 2025-01-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Maxine Atuheirwe
ID:
COVID-19 vaccine hesitancy: misinformation and perceptions of COVID-19 vaccine safety/uptake among health care workers versus general public in Uganda
REFNo: HS2013ES

d. To understand the impact of misinformation on COVID-19 vaccine up take,c. To compare vaccine acceptance among health care workers versus general public in Uganda ,b. To compare the attitudes and beliefs towards COVID-19 vaccine among health care workers versus general public in Uganda.,a. To assess knowledge of COVID-19 vaccine among health care workers versus general public in Uganda, and its correlation with intent to get vaccinated,The overall goal of the project is to understand the impact of misinformation on COVID-19 vaccine up take which will be addressed by three objectives; ,
 Uganda 2022-01-28 2025-01-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
 Peer-led HIV self-testing to improve HIV testing and linkage to HIV care among men in two fishing communities in rural Uganda: a pilot intervention (PEST4MEN)
REFNo: HS2034ES

1. Assess uptake of HIV testing and determine the factors associated with HIV testing uptake among men reached through peer-led HIV self-testing 2. Determine the proportion of HIV-positive men who link to HIV care and the factors associated with linkage to HIV care after peer-led HIV self-testing 3. Assess negative outcomes of peer-led HIV self-testing (e.g. intimate partner violence, marital disruption, suicidal ideations) and document the existing supporting mechanisms in the community 4. Explore the barriers to and facilitators of linkage to and retention in HIV care following peer-led HIV self-testing within a fishing community setting 5. Assess the potential for peer-led HIV self-testing as a novel strategy for reaching high-risk HIV-negative men in the fishing communities with appropriate HIV prevention services (including referral for medical male circumcision, condom promotion/supplies and PrEP)
Uganda 2022-01-28 2025-01-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Kirabira Raymond
ID:
Assessing the Role of Actors in Transitional Justice: The cases of Myanmar and Uganda
REFNo: SS1082ES

The project aims to examine the Transitional Justice(TJ) processes in Myanmar and Uganda. The goal is to examine whether, and to what extent, TJ is influenced by international actors? It asks two principal questions. First, how have the actors influenced the current TJ initiatives. Second, how has this affected the legitimacy of the TJ processes?
The project aims to recommend more effective ways of implementing TJ.
Uganda 2022-01-27 2025-01-27 Social Science and Humanities Non-Clinical Trial Degree Award
Neil Scolding
ID: UNCST-2021-R012864
 The clinical neurology of chronic Nodding Syndrome: a proposal for a secondary usage of clinical data for research
REFNo: HS1848ES

To analyse and publish our previously-obtained clinical and neurological information on NS, gained from clinical encounters with NS suffers
 UK 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bob Rich Mwecumi  Muhereza
ID:
DIGITAL MIGRATION AND COVERAGE OF DIGITAL TELEVISION SERVICES IN UGANDA
REFNo: SIR85ES

i. To establish the relationship between cost of digital infrastructure and coverage of digital TV services in Uganda.
ii. To establish the relationship between consumer awareness and coverage of digital TV services in Uganda.
iii. To assess the effect of subscription payments on coverage of digital TV services in Uganda.
iv. To investigate the effect of special interactive services on coverage of digital TV services in Uganda.

 Uganda 2022-01-27 2025-01-27 Engineering and Technology Non-Clinical Trial Degree Award
Robert Newton Edward
ID: UNCST-2023-R006537
 International Prevalence Surveys of Helicobacter pylori in High and Low Risk Areas for Stomach Cancer Epidemiological iNvestigatIon of Gastric Malignancies – ENIGMA
REFNo: HS1891ES

Objectives of the research project: i. To estimate the age-specific prevalence of Helicobacter pylori infection as predictor of Gastric Cancer trends. ii. To investigate bacterial, host and environmental factors associated with differences between high and low Gastric Cancer risk areas. iii. To measure H. pylori antibiotic resistance to Metronidazole and Clarithromycin in the different geographic regions. iv. To further explore the association between H. pylori infection and child growth
UK 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Field Performance Evaluation of the Xpert® HIV-1 Viral Load assay for Viral Load (VL) monitoring in Uganda
REFNo: HS1977ES

To determine acceptability of the the Xpert® HIV-1 Viral Load assay by the study participants.,To determine changes in turn-around time and ease of clinic workflow integration,To determine the operational characteristics of the Xpert® HIV-1 Viral Load assay, such as ease of-use of the assay using the standardized system usability scale (SUS) by laboratory and no laboratory personnel ,To evaluate the diagnostic accuracy using the sensitivity, specificity, NPV, PPV, FPR and FNR of the Xpert® HIV-1 Viral Load assay in comparison to a reference assay, Roche COBAS 8800 in identifying HIV-VF at the WHO recommended threshold of 1000 copies/ml for HIV-1 infected. ,To evaluate the field performance of the Xpert® HIV-1 Viral Load assay in identifying virological failure (VF) in adults on ART. The performance will be compared to the reference assay, the Roche COBAS 8800 used at UNHLS. ,
 Uganda 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Designing an intervention to increase HIV self-testing uptake and clinic linkage among men in Uganda: A Discrete Choice Experiment
REFNo: HS1061ES

Aim 1: To pilot test two HIVST Discrete Choice Experiments on 1) distribution strategies and 2) linkage strategies to assess how well participants understand the questionnaire and inform final design.

Aim 2: To conduct a DCE to determine men’s preferred HIVST distribution strategy to increase uptake. We will assess men’s preference for mode of HIVST distribution (e.g. pharmacy, drug shop, clinic, partner, friend), pre-test support, and post-test support.

Aim 3: To conduct a DCE to determine men’s preferred intervention to increase clinic linkage for HIV care and prevention after HIVST. We will assess the potential of financial incentives, screening for other diseases, fast-track services, and peer navigators to motivate men to link to care.
 Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Non-degree Award
Samuel Meyerson
ID:
From the Kraals to the Markets: A Pastoral World Beyond the State in East Africa
REFNo: SS1045ES

1. To analyze the transnational networks that have connected Ateker communities in East Africa from the precolonial era to the present day. 2. To examine the historical relationships between Ateker communities and state structures in East African countries during the colonial and post-independence periods. 3. To use historical analysis to identify ways of fostering national integration and sustainable development in Karamoja.
Canada 2022-01-25 2025-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
FREDRICK MAKUMBI
ID:
Assessment of the Scale, Reach, Quality, and Cost of Service Delivery High Impact Practices in Family Planning in Uganda
REFNo: HS2005ES

To estimate the costs of implementing and sustaining service delivery, and identify the cost drivers, and efficiencies for selected HIPs in Uganda ,To assess the quality of services for selected service delivery HIPs, including policy-level intention and readiness of services to offer the HIP in Uganda ,To measure the current reach of selected service delivery HIPs to sub-populations by age, urban/rural location of service delivery points, and, if applicable, new FP users in Uganda,To measure the current horizontal and vertical scale of implementation of 3 service delivery HIPs in Uganda,The goal of this assessment is to develop and apply a replicable approach that measures the scale, reach, quality, and cost of HIPs, information which will help Uganda and other countries to critically analyze and maximize their investments in comprehensive FP strategies. ,
 Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
 Safety and Efficacy of COVIDEX™ Therapy in Management of adult Covid-19 Patients in Uganda: A randomized double-blind placebo controlled adaptive phase 2 B clinical trial.
REFNo: HS2041ES

3. To determine the plasma concentration of berberine in COVID-19 patients receiving COVIDEX. ,2. To determine the efficacy of COVIDEXTm for treatment of COVID-19 among adults in Uganda.,To determine the efficacy of COVIDEXTm for treatment of COVID-19 among adults in Uganda.,To validate the safety and determine the efficacy of COVIDEXTm therapy for treatment of COVID-19 in adult Ugandans. ,
 Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Clinical Trial Non-degree Award
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