Emmanuel Musisi
ID: UNCST-2020-R004472
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IDENTIFICATION AND EVALUATION OF BIOMARKERS FOR MYCOBACTERIUM TUBERCULOSIS DETECTION AND MONITORING RESPONSE TO ANTI-TUBERCULOSIS THERAPY
REFNo: HS1378ES
(i) To measure the accuracy of TB-MBLA in detecting TB in sputum and non-sputum samples with reference to standard of care tests (Xpert MTB/ RIF/Ultra, sputum microscopy and culture)
(ii) To determine accuracy and utility of TB-MBLA in monitoring TB treatment response and predicting treatment outcomes in comparison with standard of care tests
(iii) To examine the correlation of TB-MBLA-measured sputum bacillary load and host gene markers for monitoring treatment response and outcome
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Uganda |
2022-05-10 18:22:50 |
2025-05-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Agnes Nakakawa
ID:
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Towards an ICT-driven Community-based Nutrition Education network for increasing awareness and knowledge transfer on Maternal Nutrition (NEMAT)
REFNo: SS1224ES
AIM:
The research aims at increasing community-level awareness on maternal nutrition and adoption of healthy nutrition practices among women of reproductive age, through establishing an ICT-driven community-based nutrition education network for supporting transfer of information/knowledge on maternal nutrition aspects.
SPECIFIC OBJECTIVES
Specifically, this research will:
1) Increase availability and accessibility of maternal nutrition information/knowledge, through developing an ICT platform for disseminating IEC materials on maternal nutrition.
2) Enable timely sharing of information/knowledge on challenges in maternal nutrition and solution/best practices, through supporting interactive dialogue between health and nutrition specialists and women at community level.
3) Enable contextual understanding of maternal nutrition aspects and required interventions, through prompting women to provide feedback on IEC materials and devising control measures for continuous improvement of IEC materials.
4) Ensure existence of an operational multidisciplinary and community-based stakeholder network, through leveraging on the role of community health extension workers to establish the network and continuously monitor its performance.
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Uganda |
2022-05-10 17:20:25 |
2025-05-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Samuel Okech George
ID:
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Assessing ethical conflicts and moral distress among veterinarians in Uganda.
REFNo: A177ES
1. Establish the awareness of veterinarians in Uganda about ethical dilemmas and moral distress
2. Determine causes, nature and extent of ethical dilemmas and the degree of moral distress they cause.
3. Determine coping mechanisms employed by veterinarians against ethical dilemmas and moral distress.
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Uganda |
2022-05-09 19:06:32 |
2025-05-09 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Angela Gallego Sala Victorina
ID:
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TroPeaCC: Tropical Peatlands and the Carbon Cycle
REFNo: NS310ES
Tropical peatlands are the most carbon-dense ecosystems in the world and they store the equivalent of ~10 years of global anthropogenic CO2 emissions. Despite their importance, crucial questions remain about carbon cycling in tropical peatlands and improving understanding is critical as they are at high risk from deforestation and drainage for oil palm cultivation.
TroPeaCC will provide a step-change gain in our understanding of tropical peatland functioning and in projecting their response to climate change.
PI Gallego-Sala will use her unique background that bridges peatland modelling and observations to deliver a novel interdisciplinary approach to tackle four outstanding questions about tropical peatlands:
Q1: What controls the geographical distribution of peatlands in the tropics? TASK1: To assess the tropical peatland extent using a combination of models
Q2: How large is the tropical peatland CO2 sink and what are its main climatic drivers? TASK2: To characterize the drivers of carbon accumulation rates in tropical peatlands using the palaeo-archive.
Q3: How large is the methane flux in tropical peatlands? What are the main controls at the intercontinental scale? TASK3: To determine the main controls on methane fluxes in tropical peatlands, using eddy covariance, chamber-based gas flux measurements, and ground penetrating radar.
Q4: What is the overall carbon balance of tropical peatlands and how will this change in the future? TASK4: To forecast future changes of the extent of tropical peatlands, of their carbon store and of methane emissions, using the results of tasks 1-3 to parameterise and evaluate a global dynamic vegetation model that includes tropical peatlands for the first time.
The interdisciplinary approach will lead to a comprehensive understanding of the role of tropical peatlands in the global carbon cycle, allowing their inclusion in earth system models, and improving their management to optimise provision of ecosystem services including carbon capture and storage.
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Spain |
2022-05-09 19:05:30 |
2025-05-09 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Geoffrey Kachiko
ID:
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Pharmacognostic Analysis, Safety, and Effect of Immuno-Kachiks®, a Ugandan Herbal Product, on Liver Tumours, Macrophages, and Alpha-N-acetylgalactosaminidase in Wistar Rats
REFNo: HS1926ES
1. To identify the phytochemicals in the Immuno-Kachiks® herbal product.
2. To determine the acute and delayed toxicity of the Immuno-Kachiks® herbal product in male Wistar rats.
3. To determine the curative effect of the Immuno-Kachiks® herbal product against liver tumours induced in male Wistar rats.
4. To determine the effect of the Immuno-Kachiks® herbal product on serum alpha-nagalase in male Wistar rats with induced liver tumours.
5. To evaluate the effect of the Immuno-Kachiks® herbal product on the total and differential white blood cell count of male Wistar rats with induced liver tumours.
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Uganda |
2022-05-09 14:32:25 |
2025-05-09 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Mwijuka Julius Julius
ID: UNCST-2020-R014640
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Visual Art Therapy and Artistic Expression of Violence Expressed by Students in Selected Secondary Schools in Bundibugyo District
REFNo: SS825ES
2. To assess the relationship between therapeutic painting and artistic expression of sexual violence expressed by students in selected Secondary Schools in Bundibugyo District. ,1.To assess the relationship between therapeutic drawing and physical Violence expressed by students in selected Secondary Schools in Bundibugyo District.,The purpose of the study is to explore the relationship between Visual art therapy and artistic expression of violence expressed by students in selected Secondary Schools in Bundibugyo District.,
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Uganda |
2022-05-09 14:28:39 |
2025-05-09 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Alexandra Sacco
ID:
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Population Health in Endangered Red Colobus Monkeys in Kibale National Park
REFNo: NS336ES
1) Disentangle the impact of various factors on gut microbial community structure of female red colobus monkeys (Piliocolobus tephrosceles) that live in disturbed and old-growth areas across Kibale National Park, Uganda, and (2) characterize the interactions between gut microbes and female sex hormones over the reproductive cycle.
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USA |
2022-05-06 13:44:47 |
2025-05-06 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
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Andrew Mujugira
ID: UNCST-2019-R000871
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Peer led outreach to engage male partners of pregnant women in Uganda
REFNo: HS2206ES
Aim 1: To assess whether a male peer-delivered, status-neutral outreach to male partners of pregnant women increases the proportion of partners who test compared to the standard of care (invitation letters for fast-track testing and HIVST delivered by the pregnant woman).
Rationale: Innovations are needed to address the challenges associated with reaching male partners of pregnant women with HIV testing and linkage to ART or PrEP depending on their HIV serostatus.
Hypothesis: A male peer delivered, status-neutral approach to male partner engagement may overcome male partners reluctance to be tested for HIV and women’s reluctance to approach their male partners about HIV testing. Approach: We will randomize women 1:1 to the intervention or delayed arm and determine the proportion of male partners who test for HIV within 1 month after the female partner is randomized. The outcome will male partner testing based on male HIV testing in the two arms.
Aim 2: To determine the proportion of male partners who test HIV-negative and have an indication for PrEP who initiate PrEP and the proportion of partners who test HIV-positive who initiate ART compared to the SOC arm.
Rationale: Men who are HIV-negative are a priority for PrEP if they have a known HIV-positive partner or multiple partners, including during late pregnancy and postpartum when men are more likely to have sex with outside partners.
Hypothesis: Trained male peers will be effective in addressing men’s reluctance to link to ART or PrEP and facilitating linkage to care or prevention.
Approach: Men who test for HIV through either arm will be referred for ART (if HIV-positive) or PrEP (if HIV-negative and reports multiple partners or an HIV positive partner) through the trained male peer counselor in the intervention arm or health care provider in the SOC arm. We will evaluate linkage to PrEP or ART among men who test for HIV, by arm.
Aim 3: To qualitatively assess acceptability of peer-delivered, status-neutral outreach to promote HIV testing among male partners of pregnant women.
Rationale: Assessment of acceptability is a key component of evaluating any novel intervention. We will use qualitative methods to investigate acceptability and preferences for HIV testing services among male partners of pregnant women in the cohort.
Hypothesis: A peer delivered, status-neutral approach to male partner engagement will be acceptable to recipients.
Approach: We will conduct individual qualitative interviews with a randomly selected subsample of 20 male partners who received peer-delivered outreach to evaluate intervention acceptability.
Population: 150 pregnant women and ?18 years of age, with male partners of unknown status, will be recruited from ANC programs in Kampala.
Study Site: The Infectious Diseases Institute (IDI) Kasangati and Kitebi Health Center III antenatal care (ANC) clinic in Kampala, Uganda
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Uganda |
2022-05-05 11:31:35 |
2025-05-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Betty NAKASIBA LINNET
ID:
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Food security and dietary diversity in urban settings of Wakiso District Central Uganda
REFNo: SS1271ES
(iii) Explore the socio-economic and demographic factors that have a bearing on household food security and diet diversity in Urban settings of Wakiso District.,(ii) Determine the dietary diversity of households in Urban settings of Wakiso district.,(i) Assess the household food security situation and related coping strategies in Urban settings of Wakiso District.,The general objective of the study will be to establish the food security situation and dietary diversity in Urban settings of Wakiso District. ,
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Uganda |
2022-05-05 11:25:49 |
2025-05-05 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Iacopo Bianchi
ID:
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Clustering at the Business Level: Micro-Firm Markets, Competitive Forces, and Innovation
REFNo: SS1259ES
Get insights into the market structure of clusters of informal micro business and understand the potential to promote growth through product experimentation,
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Italy |
2022-05-05 11:24:34 |
2025-05-05 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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ANTHONY NUWA
ID: UNCST-2022-R011102
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A hybrid effectiveness-implementation study to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda
REFNo: HS2212ES
5) To monitor the safety and torelabilty of DP as compared to SPAQ among children 6-59 months in Karamoja when used in SMC,4) To understand the SMC implementation model, determining process, costing and acceptability outcomes for the intervention,3) To investigate the presence and change of SPAQ and DP resistance markers over time as a result of SMC implementation ,2) To determine chemoprevention efficacy of SPAQ and DP when used for SMC in Karamoja region, Uganda, and the extent to which efficacy is impacted by drug resistance and/or drug concentrations. ,1) To determine the effectiveness of SMC with DP and SPAQ in terms of its reduction in incidence of malaria infection among children aged 3–59 months,Phase 2 of this study aims to test the feasibility, effectiveness and chemoprevention efficacy of SMC with SPAQ and DP in Karamoja region in Uganda, where malaria transmission is highly seasonal, and inform malaria policy in Uganda. Accelerated adoption and scale-up of SMC will support efforts to accelerate progress in malaria control in high-burden countries.,
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Uganda |
2022-05-05 11:23:22 |
2025-05-05 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Joeri Smits Smits
ID: UNCST-2021-R013841
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Increasing savings among low-income households in Uganda study
REFNo: SS922ES
This randomized field experiment seeks to evaluate the effectiveness of several account features/add-ons in mobilizing savings and helping individuals achieve their savings goals.
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Netherlands |
2022-05-05 11:02:58 |
2025-05-05 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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DANIEL MUHANGUZI
ID:
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A Collaborative Knowledge Management Framework for Enhancing Value of Agricultural Information in Smallholder Farming Systems
REFNo: SIR100ES
The main objective of this research is to develop a collaborative information and knowledge management approach that will enable smallholders extract more value from agricultural information.,To evaluate the framework for collaborative information and knowledge management.,To investigate the ability of collaborative knowledge management in enhancing value of agricultural information and adopt it to design a framework that will enhance smallholders capacity to extract value from agricultural information.,To determine the essential elements that are important in enabling smallholders extract more value from agricultural information and formulate a theory based on literature that explains these elements.,To investigate the challenges smallholders face in extracting value from agricultural information. This was done by reviewing existing literature and conducting an exploratory survey among smallholders. ,
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Uganda |
2022-05-04 18:38:35 |
2025-05-04 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
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MARY AJIKO MARGARET
ID:
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IMPACT OF COVID 19 ON ACCESS TO PAEDIATRIC SURGERY IN TESO SUB-REGION in Uganda: A Mixed methods study
REFNo: HS2205ES
2. Explore factors that are limiting and promoting the timely and safe management of children with surgical conditions in Eastern Uganda during the COVID-19 pandemic,1.1. Compare volume and types of surgical procedures performed in. children in all hospitals and HC IVs in the entire Teso-subregion before and during the Covid-19 pandemic , The overall objective is to assess the impact of the COVID-19 pandemic on paediatric surgical activity in Teso subregion in Eastern Uganda,
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Uganda |
2022-05-04 14:26:05 |
2025-05-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Isaac Ssewanyana
ID: UNCST-2020-R014336
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Performance evaluation of an improved point-of-care test (dual target) SAMBA HIV-1 qualitative test for early infant diagnosis of HIV-1 infection in resource-poor healthcare settings
REFNo: HS2219ES
To verify the field performance (sensitivity and specificity) of the improved, dual-target SAMBA II HIV-1 Qual Test against routine Cobas Ampliprep/Taqman HIV-1 Qualitative Test Version 2.0 (DBS)- for early diagnosis of HIV-1 in exposed infants and adults. In addition, discrepant results will be analysed using Cepheid Xpert HIV-1 Qual ,
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Uganda |
2022-05-04 11:32:24 |
2025-05-04 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Peter Jackson Durham
ID: UNCST-2022-R010933
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Investigation of Serologic and Pulmonary Mediators of post-Tuberculosis Lung Fibrosis in a Ugandan cohort
REFNo: HS2172ES
Primary objective:
-To analyze the levels of cytokines and SPM’s in the blood and exhaled breath of patients with pulmonary TB at diagnosis, 6 months and one year to determine if there are differences in cytokine and SPM expression among patients who develop PTLI and those who do not.
Secondary objectives
-To identify socio-demographic and clinical risk factors associated with PTLI development and investigate associations of these characteristics with specific PTLI phenotypes.
-To document the quality of life among patients who develop PTLI. ? To develop a biobank of EBC and serum samples from subjects with PTLI and those with resolution of their lung impairment at diagnosis, conclusion of treatment and at one year from diagnosis.
|
USA |
2022-05-04 11:28:09 |
2025-05-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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JOYCE SHOMI ANDREW
ID:
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FACTORS AFFECTING ADHERENCE TO ANTIHYPERTENSIVE MEDICATION AMONG HYPERTENSIVE PATIENTS IN WAKISO PUBLIC HOSPITALS.
REFNo: HS2163ES
I. To determine the level of adherence to antihypertensive medication among hypertensive patient in Wakiso and Kasangati public health facilities.
II. To determine patient related factors affecting adherence to antihypertensive medication in Wakiso and Kasangati public health facilities.
III. To determine clinical related factors affecting adherence to antihypertensive medication in Wakiso and Kasangati public health facilities.
IV. To determine medication related factors affecting adherence to antihypertensive medication in Wakiso and Kasangati public health facilities.
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Tanzania |
2022-05-03 14:26:47 |
2025-05-03 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Hedwig Acham
ID: UNCST-2022-R011459
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Developing a photographic Figure-Rating Scale to reduce malnutrition among infants and young children of mothers with a low level of literacy in Buyende district
REFNo: HS2137ES
1) To develop an innovative photographic figure-rating rating scale, for use at local level to assess nutritional status of children at 9 months
2) To determine accuracy, perception and satisfaction of mothers with use of the tool for predicting the nutritional status of their children.
|
Uganda |
2022-05-03 13:39:52 |
2025-05-03 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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MILTON NUWABIMPA RWIITA
ID:
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THE QUALITY OF HIGHER EDUCATION AND EMPLOYABILITY OF GRADUATES FROM SELECTED UNIVERSITIES IN SOUTH WESTERN UGANDA
REFNo: SS1275ES
1. To determine the relationship between the quality of curriculum and the employability of graduates from selected Universities in South Western Uganda.
2. To establish the relationship between the quality of students enrolled in the University and the employability of graduates from selected Universities in South Western Uganda.
3. To establish the relationship between the quality of teaching and the employability of graduates from selected Universities in South Western Uganda.
|
Uganda |
2022-05-03 13:06:09 |
2025-05-03 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Emmanuel Sendaula
ID: UNCST-2020-R014767
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Utility of the interRAI Check-Up Comprehensive Geriatric Assessment (CGA) Tool: Evaluating Check-Up Acceptability in Assessing Frailty and Care Needs of Older Adults with Human Immunodeficiency Virus (HIV) in Kampala District of Uganda
REFNo: HS2229ES
- determine the acceptability and perceptions of using a standardized instrument for assessment and care planning for older persons living with HIV,- identify specific care needs of older adults living with HIV,- estimate the association between HIV status and (i) one primary outcome; activities of daily living, and (ii) two secondary outcomes; health stability and cognitive function in older persons,- characterize the sociodemographic, clinical, neuropsychiatric, and functional characteristics of older persons living with and without HIV,
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Uganda |
2022-05-03 13:04:16 |
2025-05-03 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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