Francis Omujal
ID: UNCST-2019-R000428
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INVITRO PROPAGATION, PHYTOCHEMICAL AND PHARMACOLOGICAL EVALUATION OF Prunus africana, Warburgia ugandensis, Leonotis nepetifolia AND Aspilia africana OF UGANDA
REFNo: NS130ES
1. To develop an efficient in vitro propagation protocol for P. africana, W. ugandensis, L. nepetifolia, and A. africana.
2. To conduct genetic fidelity assessment and also use Fourier Transform Near-Infrared (FT-NIR) Spectrometer and Soil-Plant Analyses Development (SPAD) to characterize and compare the chemical and chlorophyll content parameters respectively in vitro generated plants.
3. To analyze the phytochemicals in P. africana, W. ugandensis, L. nepetifolia, and A. africana.
4. To evaluate the in vitro and/or in vivo medicinal activities of the different parts of the plants (stem bark, roots, and leaves) on targeted disease conditions i.e. P. africana (prostate cancer and related disease conditions); W. ugandensis (malaria and other conditions including its anti-inflammatory); L. nepetifolia (Malaria), A. africana (Malaria, wound healing).
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Uganda |
2022-05-16 13:11:09 |
2025-05-16 |
Natural Sciences |
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Non-degree Award |
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Silver Bahendeka Karaireho
ID: UNCST-2019-R000876
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THE UGANDA NON-COMMUNICABLE DISEASE (NCD) RISK FACTORS SURVEY 2022
REFNo: HS2184ES
6. To examine the trends of NCD and associated risk factors in the Ugandan population in relation to the 2014 NCD Risk Factors Survey and in relation to interventions against NCD that were informed by results of the 2014 NCD Risk Factors Survey.,5. To assess preventive measures for selected non-communicable conditions namely cervical cancer screening.,4. To collect data on clinical parameters important in the control and management of NCDs: weight, waist circumference, height, blood pressure, heart rate. ,3. To collect data on socio-demographic characteristics important in the control and management of NCDs: age, gender, level of education, employment, income, marital status,2. To assess the magnitude of biochemical risk factors important in the management of NCDs: raised blood glucose and total cholesterol.,1. To assess the magnitude of the following behavioural risk factors for NCDs:- physical inactivity, tobacco use and harmful use of alcohol and unhealthy diet. ,To determine the magnitude and the associated risk factors of non-communicable diseases (NCDs) among the Ugandan population.,
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Uganda |
2022-05-16 10:36:32 |
2025-05-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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LWABI PETER SOLOMON
ID:
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Quality of Life in Ugandan Children and Young Adults with Repaired Congenital
Heart Disease: Mixed Methods Approach Research objectives
REFNo: HS2115ES
Primary Objective: Assess quality of life in Ugandan children and young adults who have undergone surgery or interventional catheterization for congenital heart disease (CHD).
Secondary Objective(s): Assess clinical and demographic factors that impact quality of life in CHD
population.
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Uganda |
2022-05-16 10:33:45 |
2025-05-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Timothy Muwonge Ronald
ID: UNCST-2020-R014680
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Pharmacy Delivery of PrEP and HIVST for Adolescent Girls and Young Women seeking Emergency Contraception at Community Pharmacies in Uganda: Formative Research
REFNo: HS2037ES
Aim 1: To assess the willingness of providing HIV self-testing and PrEP to AGYW seeking emergency contraception at community pharmacies.
Approach: Using the social-ecological model, fig 2, we will conduct surveys with AGYW approximately 130 seeking EC at community pharmacies within a radius of 45km from the Infectious Diseases Institute-Kasangati (IDI-K) research center, to evaluate knowledge of HIVST and PrEP and acceptability of accessing HIVST and PrEP through a pharmacy. In addition, we will purposefully select a subsample of up to 30 to undergo in-depth interviews (IDIs) to explore potential barriers and facilitators of HIVST and PrEP delivery at community pharmacies.
Hypothesis: AGYW seeking EC at community pharmacies will be willing to use HIVST and PrEP and will highlight potential barriers and facilitators to accessing PrEP at community pharmacies
Aim 2: To identify readiness of pharmacy providers regarding AGYW sexual health and specifically HIVST, emergency contraception, and PrEP
Approach: To assess the readiness, knowledge gaps, and training needs of community pharmacists to deliver HIVST and PrEP alongside EC, we will conduct up to 20 IDIs with providers (pharmacy technicians, nurses, and pharmacists) from private pharmacies who under the pharmaceutical society of Uganda have agreed to be included in the study.
Hypothesis: Addressing knowledge gaps of pharmacy providers will inform delivery of sexual health services to AGYW.
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Uganda |
2022-05-13 9:02:19 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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John Mukisa
ID:
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Host genetic variation and association with HIV disease progression among pediatric cohorts in Botswana and Uganda
REFNo: HS1841ES
1) To identify common host genetic variants associated with HIV disease progression among pediatric HIV cohorts from Botswana and Uganda. 2.) To evaluate the performance of genotype imputation methods with whole genome sequences as a gold standard for determining missing genotypes among samples from Botswana and Uganda. 3.) To identify and validate KIR genotypes among children with HIV in Botswana and Uganda. 4.) To determine the KIR haplotypes associated with HIV disease progression among children with HIV from Botswana, and Uganda.
|
Uganda |
2022-05-13 7:48:00 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Agnes Kiragga
ID:
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SARS-CoV-2 international biorepository and diagnostic test performance
REFNo: HS1808ES
Primary:
• To create a biorepository to test retrospectively the performance of investigational, emerging diagnostic technologies in the intended population or setting compared to a reference comparator for diagnosing SARS-CoV-2 infection using frozen samples.
Secondary
• To test prospectively the accuracy of investigational, emerging diagnostic technologies in the intended population or setting compared to a standard comparator for diagnosing SARS-CoV-2 infection
• To determine agreement between self-collected nasal swabs, saliva and clinician-collected nasopharyngeal swab samples for the diagnosis of SARS-CoV-2 using a reference test in Uganda.
• Determine the proportion of non-reportable results (unresolved, indeterminate and incomplete) and turn-around time compared to reference test.
• To assess acceptability of self-collected nasal swab tests and saliva for testing SARS-CoV-2 in both participants and healthcare workers in Uganda.
• To explore socio-demographic, behavioural and clinical factors associated with positive SARS-CoV-2 diagnosis.
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Uganda |
2022-05-13 7:45:44 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Kristina Roesel
ID:
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Boosting Uganda's investments in livestock development (BUILD)
REFNo: A139ES
The program is divided into four different components that will be aligned and integrated, especially on activities that involve national stakeholder engagement and capacity building.
Component 1 on Peste de petits ruminants (PPR) combines socio-economic studies, vaccine targeting and delivery, regional Pan-African networking activities (e.g. PENAPH, PPR alliance GPRA) and capacity development at the Biosciences eastern and Central Africa (BecA)-Hub at ILRI Nairobi:
Objective1: Develop a socio-economic framework to assess the impact of PPR interventions
Activities: Household survey in different livestock production systems; Longitudinal study-sentinel households; System dynamic modeling; Focus group discussions
Outputs: Livelihoods impacts of different PPR control options
Objective 2: Update the epidemiological status of PPR to allow assessment of control options
Activities: Cross-sectional survey in different livestock productions systems; Post vaccination sampling; Genetic characterization of PPRV isolates; Participatory disease search; Slaughter house surveillance; Develop PPR risk maps
Outputs: Updated risk map of PPR, circulating PPR genotypes, other important SR diseases
Objective 3: Capacity development
Activities: Support review of National PPR control strategy; Review of animal health services; Multi-stakeholder platform for AH service delivery to discuss gaps and define new mechanisms for control and surveillance; Strengthen passive surveillance system; Awareness creation of farmers; Post vaccination sampling
Outputs: Novel models of animal health service delivery, strengthened surveillance system, capacity enhanced
Component 2 on Rift Valley fever (RVF) includes the characterization of animal and human samples from outbreaks in 2016 and 2018, socio-economics, development of a risk and vulnerability map for Uganda as a decision-making tool
Objective 1: Improved knowledge on RVF epidemiology
Activities: Genotyping (RVF and other viruses); Serology (establish Gn/Gc distribution); Outbreak response; Entomological studies; Risk mapping
Objective 2: Socio-economic studies
Activities: Ex-ante analyses of control options; KAP questionnaire surveys; Gender assessments – exposure and constraints on uptake of interventions
Objective 3: Develop National action plans/policy work and extension
Activities: Contingency plans/decision support tools; Community trainings
Outputs: RVF risk map, genetic characterization of circulating strains (informs vaccine interventions), Improved RVF national action plans, Training and communication materials, capacity building, improved capacity on vector sampling/surveys and biological sampling; PhD/MSc training
Component 3 on Antimicrobial resistance (AMR) will contribute to the finalization of the National AMR action plan, describe and quantify the use of antimicrobials in the peri-urban poultry value chain.
Objective 1: Understand knowledge, attitude, practices, and incentives for AMU in poultry value chains in Uganda, and the role of formal and informal markets
Activities: Literature review on AMR and AMU in the poultry sector in Uganda; Gender sensitive rapid appraisal with AMUSE tool; Identify possible intervention entry points to improve AMU
Objective 2: Assess risks to humans from poultry-associated AMR: Research on AMR transmission risks at the human-animal-environmental interface in different poultry production systems (smallholder and commercial; rural and peri-urban) in Uganda
Activities: Map possible transmission pathways within the production system; Conduct AMR and residue prevalence surveys; In-depth AMR transmission studies that include environmental samples, and farm workers, and samples from other animal species potentially housed together with poultry; Outline risk pathways for human exposure to AMR from poultry production
Objective 3: Design and evaluate interventions to reduce AMU in poultry value chains in Uganda
Activities: Design interventions (co-design with poultry producers), closely monitor implementation over time to understand incentives to motivate change; Establish drug use monitoring system in poultry farms to allow M&E; Qualitative and quantitative analysis of intervention impact
Objective 4: Support evidence-based policy dialogue for antimicrobial surveillance and AMR strategies
Activities: Organise multi-stakeholder workshops to discuss feasibility, challenges, and constraints in implementing NAP in poultry sector, involve representatives from other countries and support continued review of NAP
Objective 5: Build capacity in value chain actors, implementers, researchers
Activities: Conduct capacity development need assessment; Develop capacity development plan for different stakeholder groups
Component 4 on Veterinary Public health (VPH) at the point of slaughter includes scaling of already piloted butcher training curricula and implementation of abattoir-based sentinel studies for animal disease surveillance
Objective 1: development of curriculum for capacity building of meat handlers on good hygienic practices (slaughter house personnel, butchers, meat transporters); meat inspectors on carcass inspection and mobile reporting; Public engagement of consumers; laboratory personnel (GLP and quality assurance)
Activities: Baseline assessment of meat handlers’ knowledge and practices; hygiene indicators, selected pathogens; Consolidation and adaptation of existing materials for training of butchers; assessment of suitability of consolidated training materials and delivery mode with stakeholders; delivery of the training; endline study to assess success of the intervention
Objective 2: proof-of-concept slaughterhouses as sentinels for zoonotic disease
Activities: Mapping slaughterhouses through key informants and GIS; grey and published literature review; prioritization of disease in slaughterhouses/ identification of critical control points – KII and FGD with vets, meat inspectors, public health staff; Ethnographic observation of slaughterhouses; biological survey in animals and humans
|
Germany |
2022-05-13 7:44:12 |
2025-05-13 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
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REBECCA CLAIRE LUSOBYA
ID:
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Knowledge, Attitudes and Practices of Pediatricians, Neonatal Nurses and Parents of Preterm Infants towards Retinopathy of Prematurity in Tertiary Hospitals Uganda.
REFNo: HS2228ES
To determine the attitudes and practice patterns regarding ROP and its risk factors among pediatricians, neonatal nurses and caregivers at Kawempe National Referral Hospital and Mulago Specialized Women’s and Neonatal Hospital.,2 To determine the level of knowledge of ROP and its risk factors among caregivers attending Kawempe National Referral Hospital and Mulago Specialized Women’s and Neonatal Hospital.,1. To determine the level of knowledge of ROP and its risk factors among pediatricians and neonatal nurses in Kawempe National Referral Hospital and Mulago Specialized Women’s and Neonatal Hospital.,To determine the knowledge, attitude and practice patterns regarding ROP among the pediatricians, neonatal nurses and the preterm caregivers at Kawempe National Referral Hospital and the Mulago Specialised Women’s and neonatal Hospital.,
|
Uganda |
2022-05-13 16:09:48 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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JUSTUS BARAGEINE KAFUNJO
ID: UNCST-2020-R014150
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Identifying Opportunities for Prevention of Adverse Outcomes Following Female Genital
Fistula Repair
REFNo: HS2033ES
Identify predictors of post-repair fistula breakdown and recurrence
Identify predictors and characteristics of post-repair incontinence
Identify feasible and acceptable strategies for modifying key risk factors of adverse
outcomes
|
Uganda |
2022-05-13 16:09:08 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Emmanuel Rukundo NSHAKIRA
ID: UNCST-2021-R012277
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COVID-19 Risk,Electoral Violence and Civic Participation in the 2020/2021 Ugandan General Elections
REFNo: SS1218ES
To establish the extent to which COVID-19 fear affected civic participation in the 2021 elections,Compare the level of fear of Covid-19 and fear of electoral and post-electoral violence on voter turn-out,Assess the effect or concern and fear of COVID-19 affect voter turnout,Assess the effect of COVID-19 on campaign rally participation and candidate interface,
|
Uganda |
2022-05-13 15:52:13 |
2025-05-13 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Jackson Orem
ID: UNCST-2021-R012016
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Factors that affect the timely diagnosis and treatment of neutropenic fever in Ugandan patients with cancer and HIV
REFNo: HS2175ES
1. To understand the current process of antibiotic initiation for patients with cancer and neutropenic fever at the UCI.
2. To identify factors that influence timely initiation of guideline-recommended antibiotics which can be addressed using targeted implementation strategies.
3. To identify the unique barriers to diagnosis and treatment of neutropenic fever for patients with HIV who are receiving treatment for cancer at UCI.
|
Uganda |
2022-05-13 10:09:59 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Charles Batte
ID: UNCST-2021-R013587
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Validation of the Chronic Obstructive Pulmonary Disease Assessment Tool (CAT) Among COPD patients in rural Uganda.
REFNo: HS2145ES
To validate CAT among COPD patients in Nakaseke, Uganda.
Specific objectives:
• To determine the validity of CAT in assessing quality of life among COPD patients in rural Uganda using Saint George Respiratory Questionnaire (SGRQ) as the gold standard
• To determine the internal reliability of the CAT in diagnosis of QOL among COPD patients in rural Uganda.
Secondary objective:
• To determine factors associated with poor QoL among patients with COPD in rural Uganda.
|
Uganda |
2022-05-13 10:05:27 |
2025-05-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Claude Raisaro
ID:
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Driving Behaviors, Monetary Incentives and Norms: Experimental Evidence from the Ugandan Transit Industry
REFNo: SS1217ES
• To better understanding the underlying mechanisms to understand and incentivize safe driving behaviors for bodaboda drivers
• Examine how financial incentives affect driving behavior and to which extent is road safety impacted on an individual basis?.
• To learn whether beliefs about safe driving change in the presence of financial incentives.
|
Italy |
2022-05-13 10:01:06 |
2025-05-13 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Travis Baseler Andreas
ID:
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The Effects of Voluntary Relocation and Forced Displacement by Natural Disasters: Evidence from Ugandan Landslides
REFNo: SS1263ES
We intend to study the economic effects of displacement following environmental disasters, with a focus on the displaced population. Our goal is to identify mechanisms behind economic outcomes for the displaced, to inform future adaptation policy and humanitarian responses. The setting of this study is landslide episodes in Eastern Uganda in 2010-2019, which have displaced nearly 10,000 people.
|
USA |
2022-05-12 8:00:58 |
2025-05-12 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Stella Neema
ID: UNCST-2019-R000814
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Knowledge, acceptability and Perception of Schistosomiasis and its treatment in Pre-school aged Children in Uganda
REFNo: SS1269ES
To ascertain knowledge on and perception of (pediatric) Schistosomiasis and acceptability of its treatment in PSAC on different levels
To identify the demand of health education to inform the social mobilization and advocacy WP2
To analyse facilitators and barriers towards implementation of L-PZQ distribution for PSAC on different levels
To inform planned interventions of the subsequent work packages on advocacy, social mobilization and communication strategies for the L-PZQ rollout based on the above-mentioned outcomes and assess L-PZQ implementations in the study sites
|
Uganda |
2022-05-12 7:59:47 |
2025-05-12 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Femke Bannink Mbazzi Bannink
ID: UNCST-2023-R008308
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YOUNG AFRICA WORKS: DISABILITY INCLUSION RESEARCH PARTNERSHIP.
REFNo: SS1195ES
• To examine the policy environment and available programmes related to employment, education of youth with disabilities
• To explore the lived experiences around inclusion in education and employment from the perspective of youth with disabilities
• To identify key challenges, facilitators, gaps and opportunities relating to inclusion in education and employment for youth with disabilities
|
Netherlands |
2022-05-10 9:21:32 |
2025-05-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Herbert Kayiga Kayiga
ID:
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EFFECTIVENESS, ACCEPTABILITY AND UPTAKE OF EARLY VERSUS STANDARD INTRAUTERINE CONTRACEPTION FOLLOWING PROVISION OF FIRST TRIMESTER MEDICAL POST ABORTION CARE IN CENTRAL UGANDA
REFNo: HS2111ES
1. To determine the proportion of women who take up IUC after mPAC for 1st trimester incomplete abortion.
2. To compare the expulsion rates at six months between early versus standard IUC insertions post mPAC treatment for first trimester incomplete abortion.
3. To compare the IUC continuation rates at six months between early versus standard IUC insertion post mPAC treatment for first trimester incomplete abortion.
4. To explore the women and their spouses' perception on Long Acting Reversible Contraceptives (LARC) and IUC following mPAC treatment.
5. To explore the Healthcare providers' perception on LARC and IUC following mPAC treatment.
|
Uganda |
2022-05-10 9:21:09 |
2025-05-10 |
Medical and Health Sciences |
Clinical Trial |
Degree Award |
|
Kizito Omona
ID: UNCST-2022-R011106
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Exploring Child-based Strategies in addressing Child-to-Child Violence in Primary Schools in Kitgum District, Northern Uganda
REFNo: SS1277ES
3) To find out how children use formal peer group-based strategies to overcome child-to-child violence in primary schools in Kitgum district.,To investigate how children involve their teachers and counsellors to overcome child-to-child violence in primary schools in Kitgum district.,To find out how children use formal peer group-based strategies to overcome child-to-child violence in primary schools in Kitgum district,To establish how children apply informal peer group-based strategies to overcome child-to-child violence in primary schools in Kitgum district.,To find out the individual child-based strategies used to overcome child-to-child violence in primary schools in Kitgum district,The general objective is to explore child-based Strategies in addressing child-to-child violence in Primary Schools in Kitgum District. ,
|
Uganda |
2022-05-10 9:19:59 |
2025-05-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Toke Wolff Moldrup
ID:
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CERTIZENS: Certifications of Citizenship in Africa
REFNo: SS958ES
CERTIZENS is concerned with the ways in which states and citizens respectively get made, remade or unmade through inter-related systems, policies and practices associated with citizen classification, identification and certification.
|
Denmark |
2022-05-10 9:14:40 |
2025-05-10 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Victoria Nankabirwa
ID: UNCST-2021-R011871
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A multi-country, epidemiologic study to assess the interferon gamma release assay (IGRA) positivity, and to build capacity to conduct a tuberculosis (TB) vaccine efficacy study, in populations with a high TB disease burden
REFNo: HS2187ES
•To describe the proportion of IGRA positivity by site.
•To assess the association of age with proportion of IGRA positivity, by site.
•To describe the overall incidence of suspected and laboratory-confirmed pulmonary TB (disease).
•To describe changes in the proportion of IGRA positivity, by site.
•To describe the association between IGRA interferon gamma (IFN???concentration at screening and progression to pulmonary TB.
|
Uganda |
2022-05-10 9:13:30 |
2025-05-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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