Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Emma Ndagire Tina
ID: UNCST-2022-R010041
Assessing the Feasibility of adopting an Acute Rheumatic Fever Diagnosis and Management Algorithm in Uganda
REFNo: HS2542ES

1. Determine how accurately frontline health care providers at selected health facilities in Wakiso district implement the ARF algorithm in Uganda.

2. To determine the factors that will influence the adoption of a novel ARF diagnostic and management algorithm by health care providers at selected community health facilities in Wakiso district.

Uganda 2022-11-23 12:42:36 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
Effectiveness of Intensive Adherence Counselling on Viral Load Suppression among Adolescents and Adults Living with HIV in Uganda
REFNo: HS2553ES

o explore the facilitators of and barriers to repeat VL suppression after IAC completion among adolescents and adults on ART with an initial VL ?1,000 copies/ml after ?6 months of ART in Kampala, Uganda using a qualitative case study design (Aim 3),To examine the risk factors for repeat VL persisting at ?1,000 copies/ml after completing IAC among adolescents and adults on ART with an initial VL ?1,000 copies/ml after ?6 months of ART in Kampala, Uganda using a nested case-control study design.,To evaluate the impact of IAC on VL suppression and all-cause mortality among adolescents and adults on ART with VL ?1,000 copies/ml after ?6 months of ART in Kampala, Uganda using a regression discontinuity design,
Uganda 2022-11-23 12:41:12 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muniirah Mbabazi
ID:
Gender dynamics in accessing and utilizing Nutrition and WASH services-An exploratory study.RefNO:2022-392
REFNo: HS2544ES

Document key recommendations for advocacy on gender, nutrition and WASH and local and national levels.,Examine how gender dynamics influence access and utilisation of nutrition and WASH services at household and community levels in Maracha and Bugweri districts,Undertake a document review to identify policy gaps in key policy documents on nutrition, WASH and gender in Uganda,To examine how gender dynamics shape access and utilisation of WASH and nutrition services in promoting women’s leadership, decision making, promoting equal and positive gender norms, improving access to resources as well as building contextual research evidence on local resilience, sustainability in Maracha and Bugweri districts in Uganda,
Uganda 2022-11-23 12:39:59 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Hope
ID:
Strengthening national capacity for tsetse control in Uganda
REFNo: SS1490ES

The primary aim of this study is to monitor and assess the implementation of the action plan to strengthen the capacity for implementing tsetse control at COCTU and in the Districts where tiny targets are deployed. This study will follow-up on the capacity strengthening action plan developed in 2017 with the aim to enable COCTU to implement tsetse control for gHAT independently of LSTM.
The aims will be achieved by the following objectives:
1. Conduct semi-structured interviews with key personnel at COCTU and the District level to fully understand the current level of execution of the action plan for strengthening the capacity to for implementing tsetse control in Uganda.

2. Conduct participatory meeting at the District level with COCTU and District staff to collaboratively assess the progress towards the establishment of a stronger and independent tsetse control system in Uganda (based on findings from objective 1).

UK 2022-11-23 12:38:07 2025-11-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Yunia Mayanja
ID:
Improving HIV Prevention among Adolescent Girls and Young Women in Uganda.
REFNo: HS2490ES

The purpose of the PhD project is to determine preferences for biomedical HIV prevention methods among 14-24-year-old adolescent girls and young women (AGYW) at risk of HIV infection and to evaluate a peer support intervention aimed at improving uptake of and adherence to oral pre-exposure prophylaxis (PrEP). Main Study Aims: i) To determine preferences for five biomedical HIV prevention methods among 14-24-year-old AGYW at risk of HIV infection in Kampala, Uganda including oral PrEP, injectable PrEP, vaginal ring, PrEP implant and HIV vaccine. ii) To evaluate a peer support intervention aimed at improving uptake of and adherence to oral pre-exposure prophylaxis (PrEP), the only currently available biomedical HIV prevention method in Uganda. Study Objectives: i. To determine preferences for five biomedical HIV prevention methods among 14-24-year-old AGYW in Kampala, Uganda, and determine factors associated with preference for oral PrEP. ii. To evaluate the effect of a peer support intervention on uptake of and adherence to oral PrEP among 14-24-year-old AGYW at risk of HIV infection in Kampala, Uganda. iii. To evaluate the effect of a peer support intervention aimed at improving oral PrEP uptake and adherence, on sexual behavior and reproductive health outcomes among AGYW in Kampala, Uganda. iv. To explore AGYW perceptions and experiences of the peer support intervention aimed at improving oral PrEP uptake and adherence.
Uganda 2022-11-23 12:36:50 2025-11-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Grace  Kentaro Maria
ID:
FEMININE IDENTITY IN ANTI-COLONIAL STRUGGLES: THE LEGACY OF MUHUMUZA OF NYABINGI MOVEMENT IN KIGEZI, UGANDA
REFNo: SS1144ES

1. To trace the origins of the Nyabingi Movement to 1900 and its goals in the history of Kigezi
2. To assess the contribution of Nyabingi movement in the anti-colonial struggles
3. To examine the contribution of Muhumuza in anti-colonial struggle as a role model in demonstrating women leadership to other women in other struggles
4. To examine the role of oral history in portraying women’s and men’s roles in anti-colonial struggles

Uganda 2022-11-23 12:32:43 2025-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
JOSEPH MWESIGWA SAMUEL
ID:
THE SELECTION OF TECHNICAL AND VOCATIONAL EDUCATION AND TRAINING OPTION BY SECONDARY SCHOOL CANDIDATES IN UGANDA
REFNo: SIR99ES

To establish the awareness of parents of students in secondary schools in Uganda about the TVET option as a career choice for their children.,To investigate the method of course selection by TVET college students in Uganda.,To determine the perception of secondary school teachers in Uganda on TVET as a career choice by the candidates.,To investigate the availability of career guidance information to secondary school candidates on TVET courses in Uganda.,The main objective of the study will be to establish the factors influencing the selection of TVET option by secondary school candidates in Uganda. ,
Uganda 2022-11-23 12:29:54 2025-11-23 Engineering and Technology Non-Clinical Trial Degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
Community-based Alternative Learning Environments for Parenting and Pregnant Teens: A Response to Uganda’s Increased Prevalence Due to the Impact of the COVID-19 Global Pandemic
REFNo: SS1487ES

This research aims to conduct a participatory assessment of factors that enhance adoption of alternative education environments for parenting and pregnant teens by involving communities in reflecting on and defining special needs for school re-entry and providing for second-chance education after pregnancy in Uganda.,To comprehensively disseminate the recommendations and guidelines for policy uptake,To co-create policy recommendations for community-based alternative education environments for parenting and pregnant teens,To conduct participatory multi-level needs assessment and policy pecommendations ,
Uganda 2022-11-23 12:28:32 2025-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
Accelerating Delivery of rheUmatic heart disease preventive iNterventions in Uganda (ADUNU)
REFNo: HS2470ES

Objective 1: Demonstrate the impact of ADUNU, using the RE-AIM framework to assess program Reach,
Effectiveness, Adoption, Implementation, and Maintenance. Objective 1 has five sub-objectives:
a) Reach – Use echocardiography to increase the proportion of individuals with RHD who are detected, including identification of sub-groups not reached (target: 50% Kitgum district] or 25% [Amuru district] detected).


b) Effectiveness – Achieve goals in (1) registry enrollment (target: 90% of those diagnosed by RHD testing), (2) retention (target: 90% of those enrolled), and (3) adherence (target: 90% of those retained).

c) Adoption – Assess the proportion of healthcare facilities and providers that adopt ADUNU and understand barriers and facilitators to adoption success.

d) Implementation – Assess the proportion of healthcare providers and facilities demonstrating high fidelity to the relevant ADUNU components and protocols in which they have been trained and reasons for suboptimal performance.

e) Maintenance – Understand the (1) proportion of facilities and providers continuing to implement ADUNU as designed, and (2) sustainment of retention and adherence levels among individuals enrolled in the registry at 24 months post-introduction

Objective 2: Estimate the cost-effectiveness and budget impact of ADUNU. This objective will build on the first objective and will use standard methods for economic evaluation of health programmes.

Uganda 2022-11-23 12:26:29 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Filippo Grisolia
ID:
One for all and all for cash? An inquiry into social network and collective action effects of cash transfers in rural Uganda
REFNo: SS1467ES

Focus on social capital, agency and collective action measures,Focus on climate change adaptation and mitigation patterns,Investigate CT effects,
Italy 2022-11-17 3:55:31 2025-11-17 Social Science and Humanities Non-Clinical Trial Degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
EFFICACY AND SAFETY OF DIHYDROARTEMISININ-PIPERAQUINE (EURARTESIM) FOR TREATMENT OF UNCOMPLICATED P. FALCIPARUM MALARIA IN ADULT PATIENTS WITH COVID-19 CO-INFECTION: AN OPEN LABEL RANDOMISED PILOT CLINICAL TRIAL (EMCOS CLINICAL TRIAL)
REFNo: HS2563ES

To evaluate the incidence of adverse events in adult participants with uncomplicated P. falciparum malaria and COVID-19 coinfection receiving DHA/PPQ treatment or Artemether – lumefantrine treatment. ,To determine the efficacy of DHA-PPQ in treatment of adult patients suffering from uncomplicated P. falciparum malaria with COVID-19 coinfection.,To assess the therapeutic efficacy and safety of DHA-PPQ for the treatment of uncomplicated P. falciparum malaria- COVID-19 co-infection.
Uganda 2022-11-17 18:12:26 2025-11-17 Medical and Health Sciences Clinical Trial Non-degree Award
TWAHA NAJJA -
ID:
“Performance of Mergers of mobile telecommunication operators in Uganda.: Does the management of employees’ expectations matter in influencing performance.” Ref No. MUST-2022-614
REFNo: SS1493ES

The general objective of this study is to examine the extent to which the management of a combination of employee communication and employee participation, herein referred to as employees’ expectations, influence post-merger and acquisition performance of mobile telecommunication operators in Uganda.
Specific objectives of the study
1. To determine the effect of management of employee communication on post- merger and acquisition performance of mobile telecommunication operators in Uganda.
2. To determine the effect of management of employee participation on post- merger and acquisition performance of mobile telecommunication operators in Uganda.
3. To establish the extent to which employee satisfaction affects the relationship between management of employee communication and post-merger and acquisition performance of mobile telecommunication operators in Uganda.
4. To establish the extent to which employee satisfaction affects the relationship between management of employee participation and post-merger and acquisition performance of the mobile telecommunication operators in Uganda.


Uganda 2022-11-17 18:03:32 2025-11-17 Social Science and Humanities Non-Clinical Trial Degree Award
MOSES EGESA
ID: UNCST-2025-R015361
Characterization of protein and glycan epitopes recognised following controlled human infection with Schistosoma mansoni in an endemic population (SmCHI-Epitope)
REFNo: HS2072ES

The aim is to identify candidate molecules (proteins and peptide or glycans) associated with protection against controlled human infection with Schistosoma mansoni in an endemic population. This study will investigate
1. antibody responses to whole recombinant proteins and peptide epitopes of surface- exposed and secreted proteins of S. mansoni after CHI-S and relate this to whether volunteers get infected or not following exposure to CHI-S
2. specific anti-glycan antibody responses after CHI-S and relate this to whether they get infected or not following exposure to CHI-S

Uganda 2022-11-17 17:58:46 2025-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michiel De Haas Alexander
ID: UNCST-2022-R009315
Mapping the Cotton Boom in Eastern Uganda c 1910-1970: Temporal and Spatial Patterns and Economic Legacies
REFNo: SS1514ES

Main objective: the creation of a geocoded database of cotton ginneries in Uganda from the establishment of the first ginnery in 1904 until today



Specific objectives:

1. map the spatial distribution and characteristics of cotton ginneries in Uganda over the period 1904 until 2022 Delete

2. Link geographical variables such as soil quality, terrain ruggedness, rainfall patterns, cotton suitability, and suitability for other crops, tsetse prevalence and distance to waterbodies to the spread of ginneries, conceptualized as the likelihood that a grid-cell with specific characteristics is ‘treated’ with the appearance and disappearance of a ginnery. Delete

3. Link ‘treatment’ with ginneries to contemporary living standards and livelihood strategies today: did historical proximity to a cotton ginnery have long-term effects on the level of income, the sources of income (agricultural and non-agricultural) and agricultural productivity?
Netherlands 2022-11-16 10:57:10 2025-11-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
STANDARD™ Q Covid-19 Ag Home Test Laymen Study including Usability." Clinical Performance Study Plan - CPSP nr. BSS-CPH 22-040"
REFNo: HS2536ES

The objective of this laymen study is to establish the usability of the STANDARD Q COVID-19 Ag Home Test in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
Uganda 2022-11-16 10:56:01 2025-11-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
Evaluation of “Inclusive Playful Parenting for a Brighter Childhood” in Uganda – a Quasi-experimental study.
REFNo: SS1498ES

• To conduct a baseline and final evaluation to document the current status and the change in: child development in motor (fine, gross), language, cognitive, social-emotional domains; parenting practices in responsive caregiving, early learning, safety security; and caregiver mental well-being scores;
• Compare and understand the impacts of high, medium, and low dose of integrated Playful Parenting interventions on caregiver and child level outcomes;
• Learn about the efficiency, feasibility of engaging different community actors, workforces to reach, influence, and support parents in communities, sustainability drivers to promote and sustain Playful Parenting;

Uganda 2022-11-16 10:54:43 2025-11-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
CLARE KYOMUHENDO
ID:
The Burden of Prenatal and Postpartum Depression among Women Living with HIV in Kampala and Wakiso, Uganda
REFNo: SS1488ES

1. Examine the prevalence of prenatal and postpartum depression in women living with HIV in Kampala and Wakiso, Uganda.
2. Assess the knowledge of prenatal and postpartum depression of women living with HIV in Kampala and Wakiso, Uganda.
3. Explore the prenatal and postpartum experiences of Women Living with HIV in Kampala and Wakiso, Uganda.
4. Investigate the relationship between perinatal status and depression among Women Living with HIV in Kampala and Wakiso, Uganda.
5. Examine the determinants of prenatal and postpartum depression among women living with HIV in Kampala and Wakiso, Uganda.
Uganda 2022-11-16 10:49:34 2025-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
Rikke Fischer Horne
ID:
Availability of Reproductive Healthcare Among Women in Gulu
REFNo: SS1513ES

Gain insight into women's experience of reproductive health care at the health units,Share knowledge with health workers and other interested parties,Enhance knowledge of reproductive healthcare availability.
Denmark 2022-11-16 10:46:38 2025-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
Mateusz Krawczyk Marek
ID:
Patterns of refugees' hybrid identity in perspective of their subjective ability to rebuild the living conditions. A case study of Nakivale Refugee Settlement in Uganda
REFNo: SS1481ES

1. develop, based on empirical research and adopted explanatory procedures, an integral theory of the hybrid identity of refugees
2. define and assess the cognitive, emotional, and volitional abilities of a human being, which enable them to undertake causative actions
3. Assessment of the extent to which aid organizations respond to the needs of refugees
Poland 2022-11-16 10:42:20 2025-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
Lukwago Ismail
ID:
A THEORETICAL MODEL FOR ADOPTION OF E-LEARNING IN HIGHER INSTITUTIONS OF LEARNING: A PERSPECTIVE OF SELECTED PRIVATE UNIVERSITIES IN UGANDA
REFNo: SIR150ES

i. To identify the adoption drivers of e-learning systems in private universities in Uganda.
ii. To investigate the extent to which ICT facilities are in use by the students in private universities in Uganda.
iii. To develop a theoretical model for adoption drivers of e-learning systems in private universities in Uganda.
iv. To validate the developed theoretical model for adoption drivers of e-learning systems in private universities in Uganda.

Uganda 2022-11-15 3:46:00 2025-11-15 Engineering and Technology Non-Clinical Trial Degree Award
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"A prosperous Science and Technology Led Ugandan Society."