Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Robert Ssekitoleko
ID: UNCST-2019-R001716
A Feasibility and Safety Study of the KeySuite Laparoscopic Devices for Cancer Diagnosis in Uganda
REFNo: SIR493ES

1. To evaluate potential safety issues associated with the use of the KeyScope in patients with intra-abdominal cancers or suspected cancers .
2. To determine the clinical performance of the KeyScope in viewing tissue masses in the abdomen.
3. To determine the clinical performance of the KeyLoop in retraction of the abdominal wall during laparoscopic surgery
4. To determine the acceptability of KeySuite laparoscopic devices in aiding to obtain laparoscopic biopsies

Uganda 2025-09-26 17:12:49 2028-09-26 Engineering and Technology Clinical Trial Non-degree Award
Martin Galiwango
ID: UNCST-2025-R017447
Image Classification in Dermatology: Real Time diagnosis of DCPA using edge computing
REFNo: SIR549ES

1. To identify the most optimal tier in the healthcare system where a DCPA diagnostic device would improve the diagnosis of DCPA based on health workers’ diagnostic accuracy and resource availability. 2. To train a deep learning model that can accurately diagnose DCPA. 3. To validate the deep learning model. 4. To implement the deep learning model on an edge-computing device that ensures data privacy.
Uganda 2025-09-26 16:31:26 2028-09-26 Engineering and Technology Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Focal mass drug administration for the prevention of malaria in pregnancy: a pilot randomized controlled trial.
REFNo: SS4303ES

1. Determine the feasibility and acceptability of a fMDA program with dihydroartemisinin-piperaquine (DP) as a novel component of the MiP prevention package. 2. Estimate the efficacy of fMDA to create a “safe zone” in the immediate home environment and ultimately prevent MiP. ,The scientific objective of this pilot study is to demonstrate the feasibility, acceptability, and preliminary effectiveness of a focal mass drug administration (fMDA) program for household members of pregnant women to protect against malaria in pregnancy (MiP).,
Uganda 2025-09-26 16:24:58 2028-09-26 Social Science and Humanities Non-degree Award
Abdullah Wailagala
ID: UNCST-2025-R019096
Anticipatory Action for Health Service Resilience and Detection (AHEAD) Discovery and Design Study
REFNo: HS6471ES

2) To understand the current and ideal approaches, practices, and perceptions of health workers regarding using risk data and/or information to trigger anticipatory actions.3) To collaboratively co-design, tools and frameworks for anticipatory epidemic risk monitoring and response, drawing on healthcare worker insights, existing workflows, and routine data systems at the primary health care level. 1) To assess the effectiveness and perceived impact of the cIDSR Ebola module released in response to the most recent Ebola outbreak in January 2025 in enhancing health facility readiness and response.
Uganda 2025-09-24 16:38:20 2028-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID  MUBIRU
ID: UNCST-2021-R013091
Epidemiology of Banana Bunchy Top Disease (BBTD) in Uganda: A recently discovered viral disease threatening banana production
REFNo: NS1028ES

1. To determine the genetic diversity of Banana Bunchy Top Virus variants in Uganda. 2. To screen for natural resistance of selected banana accessions against BBTV. 3. To compare the proteomic expression in the BBTV-infected banana in response to varying temperature and drought conditions.
Uganda 2025-09-24 16:36:26 2028-09-24 Natural Sciences Non-Clinical Trial Degree Award
Latim Emmanuel
ID: UNCST-2025-R019539
CONTINUOUS PROFESSIONAL DEVELOPMENT PROGRAMS, ORGANIZATIONAL LEARNING AND JOB PERFORMANCE OF REGISTERED ACCOUNTANTS IN UGANDA’S PUBLIC SECTOR
REFNo: SS4314ES

To examine the effect of workshops and seminars on the job performance of registered accountants in Uganda’s public sector.

To assess the effect of webinars on the job performance of registered accountants in Uganda’s public sector.

To evaluate the effect of mentoring and coaching on the job performance of registered accountants in Uganda’s public sector.

To evaluate the moderating effect of organizational learning on the job performance of registered accountants in Uganda’s public sector.

To advance a model necessary for improving the job performance of registered accountants in Uganda’s public sector.

Uganda 2025-09-24 16:35:28 2028-09-24 Social Science and Humanities Non-Clinical Trial Degree Award
Victoria Nzarubara Patricia
ID: UNCST-2024-R015837
Digital Transformation, Quality of Work Life, Subjective Well-Being and Coping strategies in the Uganda Police Force
REFNo: SS3574ES

7. To identify the most prevalent coping strategies adopted among police officers in the UPF.,6. To assess the perceptions of the police officers towards the digital transformation in the UPF.,5. To examine the experiences of the police officers in the UPF regarding their SWB. ,4. To determine whether coping strategies moderates the association between digital transformation and SWB among police officers in the UPF. ,3. To examine the association between digital transformation and SWB among police officers in the UPF.,2. To investigate the relationship between QWL and SWB among police officers in the UPF.,1. To assess the association between digital transformation and QWL among police officers in the UPF.,
Uganda 2025-09-24 16:30:15 2028-09-24 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Clinical Performance Evaluation of Alinity m HIV-1 Assay Using Plasma Separation Cards (PSC) versus Plasma Testing in Uganda
REFNo: HS6500ES

The primary objective of this protocol is to evaluate the performance, bias and correlation of quantitative measurement of HIV-1 RNA, of the investigational Alinity m HIV-1 assay viral load using PSC as compared with Alinity m HIV-1 assay viral load using plasma.
The secondary objective of this protocol is to evaluate the performance, bias and correlation of quantitative measurement of HIV-1 RNA, of the investigational Alinity m HIV-1 assay viral load using PSC as compared with cobas HIV-1 Quantitative nucleic acid test for use on cobas 6800/8800 systems using PSC samples.

Uganda 2025-09-23 11:10:47 2028-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Chidiebere  Adim Victor
ID: UNCST-2025-R018777
Borderless Hustle: Kinship, Trust, and Economic Dependency in African Refugee Entrepreneurship
REFNo: SS4082ES

This study addresses a critical gap by examining how African refugee entrepreneurs mobilize kinship networks to build trust, mitigate risk, and secure the resources necessary to navigate unfamiliar and frequently hostile entrepreneurial terrains.
Nigeria 2025-09-23 11:09:24 2028-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nakayiki Lilian Nyanzi
ID: UNCST-2025-R019152
Determinants of Indigenous Fruit and Vegetable Consumption among Adults in the Rwenzori Region, Uganda
REFNo: HS6387ES

Main Objective The study aims to assess the determinants (enablers and barriers) of indigenous fruit and vegetable consumption among adults in the Rwenzori region of Uganda. Specific Objectives include; 1. To assess the availability and diversity of Indigenous Fruits and Vegetables in food markets within the Rwenzori region. 2. To determine the total intake of fruit and vegetables (and other foods consumed) by adults (18 years and above) in the Rwenzori region. 3. To develop and validate a quantitative questionnaire for assessing the determinants (barriers and enablers) of indigenous fruit and vegetable consumption among adults. 4. To assess the barriers and enablers of indigenous fruit and vegetable consumption among adults in selected communities within the Rwenzori region using the questionnaire in objective 3.
Uganda 2025-09-23 11:07:15 2028-09-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
Is Healthcare a Common Good? Philosophical Perspectives and Clinical Practices in Boston and Kampala
REFNo: SS4184ES

1. To develop a philosophical framework for conceptualizing healthcare as a
common good by drawing on African and North Atlantic philosophical traditions.
2. Explore clinicians’ conceptions of health, the common good, and professional
practice.
3. To analyze how differing conceptions of healthcare affect experiences of burnout and moral injury.
Uganda 2025-09-23 10:58:51 2028-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Honoka Yokoyama
ID: UNCST-2024-R002478
A Study of the Educational Relationship between Teachers and Students in Ugandan Secondary Schools
REFNo: SS3639ES

The purpose of this study is to clarify how the educational relationship between teachers and students is constructed in diverse relationships under the respective rationales of teachers and students, focusing on situations such as daily student guidance and learning.
Japan 2025-09-23 10:52:39 2028-09-23 Social Science and Humanities Non-Clinical Trial Degree Award
Josephine Namatovu
ID: UNCST-2025-R017197
ASSOCIATION OF INFANT AND YOUNG CHILD FEEDING PRACTICES AND NUTRITION STATUS OF CHILDREN 6-23 MONTHS IN BIDIBIDI REFUGEE SETTLEMENT –YUMBE DISTRICT-UGANDA.
REFNo: HS6243ES

General Objective
To determine the association of Infant and young child feeding practices and nutrition status of children 6-23 months in Bidibidi refugee settlement-Yumbe District Uganda.
4.2Specific Objectives

I.To determine the nutrition status (Stunting, wasting, underweight) of children aged 6-23 months in Bidibidi refugee settlement.

II.To assess the feeding practices (IYCF) (exclusive breastfeeding, continued breast feeding, introduction of solid foods, minimum dietary diversity, minimum meal frequency and minimum acceptable diet) in relation to nutrition status of children 6-23 months in Bidibidi refugee settlement.

III.To identify barriers and facilitators influencing infant and young child feeding practices of children 6-23 months in Bidibidi refugee settlement.

Uganda 2025-09-23 10:50:34 2028-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bambeiha Asiimwe Stephen
ID: UNCST-2024-R003555
A National Survey on Health Status, Risk Behaviors and Health-Related Policies and Practices in Primary and Secondary Schools in Uganda
REFNo: HS5927ES

1. To describe the current health status in terms of physical, social, and mental well-being, among students in primary and secondary schools in Uganda 2. To describe health-related knowledge, attitudes, and practices and evaluate behavioral risk and protective factors for health among students in primary and secondary schools in Uganda 3. To assess the quality and scope of school-based health services and evaluate for disparities in these services between rural versus urban schools and private versus public schools 4. To describe challenges and good practices in school-based health services and identify opportunities for improvement
Uganda 2025-09-23 10:45:31 2028-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAPHTAL BAGUMA
ID: UNCST-2025-R020055
CREATING AN EFFECTIVE CIVIL SOCIETY ECOSYSTEM AND BOARDROOM PROTOCOLS TO ENHANCE FINANCIAL SUSTAINABILITY OF UGANDAN NGOs
REFNo: SS4209ES

Specific Objectives 1. To investigate the relationship between civic space and the perceived financial sustainability of NGOs in Uganda 2. To investigate the relationship between funding strategies and the perceived financial sustainability of NGOs in Uganda. 3. To investigate the relationship between managing donor trust and the perceived financial sustainability of NGOs in Uganda 4. To investigate the relationship between incubation and acceleration activities and the perceived financial sustainability of NGOs in Uganda. 5. To investigate the relationship between the choice of location and events, on the one hand, and the perceived financial sustainability of NGOs in Uganda, on the other hand. 6. To investigate the relationship between talent management and the perceived financial sustainability of NGOs in Uganda. 7. To investigate the relationship between training and the perceived financial sustainability of NGOs in Uganda. 8. To investigate the relationship between access to government support and the perceived financial sustainability of NGOs in Uganda. 9. To investigate the relationship between technology usage and the perceived financial sustainability of NGOs in Uganda. 10. To investigate the relationship between the management of partnership and networks, on the one hand, and the perceived financial sustainability of NGOs in Uganda, on the other hand.
Uganda 2025-09-17 15:45:17 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
KYOMUGISHA AGATHA agathakyomugisha3@gmail.com
ID: UNCST-2025-R017288
TEACHING METHODS, PERSONALITY TRAITS MONITORING AND EVALUATION AND STUDENTS’ ACADEMIC PERFORMANCE AT NATIONAL TEACHERS COLLEGES IN UGANDA.
REFNo: SS4279ES

To examine how monitoring and evaluation practices mediate the relationship between personality traits and academic performance,To explore the mediating role of monitoring and evaluation practices in the relationship between teaching methods and academic performance,To evaluate the combined effect of monitoring and evaluation practices, personality traits, and teaching methods on academic performance in Uganda’s National Teacher Colleges.,To assess the impact of teaching methods on academic performance in Uganda’s National Teacher Colleges.,To investigate how personality traits influence academic performance in Uganda’s National Teacher Colleges.,To analyze the relationship between monitoring and evaluation practices and academic performance in Uganda’s National Teacher Colleges.,
Uganda 2025-09-17 15:43:55 2028-09-17 Social Science and Humanities Degree Award
Allan Kalungi
ID: UNCST-2022-R009843
Harnessing DNA Methylation Variation Between Populations to Understand Disease Discordance Across Ancestries
REFNo: HS6352ES

i. Create a comprehensive mQTL resource: We aim to expand the diversity of methylation quantitative trait loci (mQTL) resources by incorporating genetic data from underrepresented populations, including Africa. The study will compare genetic architecture and selection signatures across populations and use mQTLs as instruments to identify causal relationships between DNA methylation (DNAm), genome-wide association studies (GWAS), and epigenome-wide association studies (EWAS) signals.

ii. Conduct multi-ancestry epigenetic analyses: We aim to explore disease discordance mechanisms between populations by conducting multi-ancestry EWAS with a focus on cardiometabolic and blood cell phenotypes. This will include cell-type-specific EWAS and variance EWAS analyses to understand differences across global populations.

iii. Improve disease and exposure prediction models: We will refine existing predictors of disease risk or exposure (such as smoking and alcohol use) by including data from multi-ancestry participants. This approach will help develop predictive models that are either generalizable across populations or optimized for specific ancestries.

iv. Form equitable partnerships: The study will foster global collaboration through co-developed training resources and shared analytical tools, ensuring that the research benefits a wide range of stakeholders across various regions

Uganda 2025-09-17 15:40:49 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AKANKWASA ALEX
ID: UNCST-2025-R018808
INTERNAL CONTROL SYSTEMS AND LOCAL GOVERNMENTS’ PERFORMANCE IN UGANDA; RUBANDA DISTRICT LOCAL GOVERNMENT
REFNo: SS4182ES

To examine the effect of financial controls on financial performance of Rubanda District Local Government.
(ii) To determine the influence of human resource controls on the staff satisfaction in Rubanda District Local Government.
(iii) To explore the relationship between systems control on the levels of customer satisfaction in Rubanda District Local Government.
(iv) To evaluate the moderating effect of staff retention on internal control systems and Performance of Rubanda District Local Government.

Uganda 2025-09-17 15:37:56 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
LYDIA NAKIGANDA
ID: UNCST-2025-R016917
A Qualitative Study Exploring the Role of Peer Navigators in Supporting PrEP Adherence and Retention Among Female Sex Workers in South-Western Uganda.
REFNo: HS6339ES

i. To examine the roles, characteristics, and relationship-building qualities of peer navigators in supporting FSW and integrating into health systems.
ii. To investigate the mechanisms and activities of peer navigation in community and healthcare settings that enhance retention and adherence to PrEP care among FSW.
iii. To explore the lived experiences of peer navigators as they balance community-based and professional identities in delivering healthcare services.
iv. To understand the socio-ecological factors that facilitate or hinder the success of peer navigation programs in supporting PrEP care for FSW.

Uganda 2025-09-17 15:35:04 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Obadia Mugabirwe
ID: UNCST-2024-R002359
CREATIVITY, INNOVATION, SKILLS DEVELOPMENT, AND YOUTH EMPLOYABILITY AMONG VOCATIONAL TRAINEES. A CASE OF VOCATIONAL AND SKILLS TRAINING INITIATIVES IN UGANDA (WESTERN REGION)
REFNo: SS3587ES

The main objective of this study is to assess the impact of creativity, innovation, and skills development on youth employability in Western Uganda, focusing on how vocational training programs can enhance employability outcomes by enhancing technical and soft skills, promoting career adaptability, and aligning training with labor market demands to improve job readiness and long-term career success. Specific Objectives 1. To assess the role of vocational training in enhancing the creativity of youth in Western Uganda and its contribution to employability. 2. To examine how vocational training influences the innovation capabilities of youth and their ability to adapt to evolving job market demands. 3. To evaluate the effectiveness of vocational training in equipping youth with both technical skills and essential soft skills such as communication, teamwork, and problem-solving. 4. To analyze how skills development mediates the relationship between creativity, innovation, and youth employability in Western Uganda. 5. To identify and measure key employability indicators—such as career adaptability, job search skills, career identity, and career proactivity—among vocational training graduates in Western Uganda. 6. To investigate barriers faced by vocational training graduates in transitioning to meaningful employment and propose strategies to enhance job placement and employability outcomes.
Uganda 2025-09-17 15:28:06 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
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