Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Zaina Nabirye Lubwama
ID: UNCST-2025-R022146
 The Persistance of Indian Built Heritage in Busoga, Eastern Uganda, 1903-2023.
REFNo: SS4509ES

1. To examine the evolution of Indian-built heritage in Busoga from 1903 to 1962.
2. To analyze how and why Indian-built heritage adapted and maintained its vitality from 1962 to 1979.
3. To examine the changes and continuities of Indian built heritage in Busoga from 1979 to 2023.

 Uganda 2025-11-21 14:58:05 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Sofia Fernandez
ID: UNCST-2025-R019676
 Investigating the lack of male involvement in community based agricultural education programs in Kamuli, Uganda
REFNo: SS4581ES

1. Examine the man's perception of their role in family nutrition and agriculture.
2. Identify the social and cultural barriers to involvement for men.
3. Collect ideas for solutions that could increase male participation.
 USA 2025-11-21 14:52:50 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ahimbisibwe
ID: UNCST-2025-R018434
 Co-ethnic Peers in Higher Education. Surname-ethnicity connection and validation exercise
REFNo: SS4575ES

1. This project will evaluate the effectiveness of using surname-based machine learning models in predicting identity with a focus on ethnic peer effects.

2. Also, we will evaluate how High-ability and co-ethnic peer networks may shape career opportunities and national identity and pride
 Uganda 2025-11-21 14:50:09 2028-11-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Micheal Ivan Lyazi Micheal Ivan
ID: UNCST-2025-R021640
 An Assessment of Gender Integration in Equity Accelerator Fund (EAF) Implementation in Uganda
REFNo: SS4547ES

1. 1. To describe the specific gender-related barriers to immunization access among Uganda’s zero-dose population archetypes. 2. 2. To assess the implementation of EAF gender integration strategies. 3. 3. To identify gaps in the implementation of EAF gender integration strategies. 4. 4. To explorer how gender integration influences the number of ZD/ under immunized cases across the different population architypes in the study Geographies.
 Uganda 2025-11-21 14:44:56 2028-11-21 Social Science and Humanities Non-degree Award
MALLON TUSUUBIRA
ID: UNCST-2025-R021850
 SURVEY ON PARATUBERCULOSIS IN SLAUGHTERED GOATS AT KAMPALA CITY ABATTIOR
REFNo: A654ES

General objective
To establish the prevalence of Mycobacterium avium subsp. paratuberculosis infection in goats
Specific Objectives
i. To determine the prevalence of the gross and microscopic lesions associated with paratuberculosis in the ileocecal junction and associated lymph nodes of goats slaughtered at Kampala city abattoir
ii. To establish the prevalence of Mycobacterium avium sub species paratuberculosis in suspected cases using polymerase chain reaction (PCR)

 Uganda 2025-11-21 14:36:09 2028-11-21 Agricultural Sciences Clinical Trial Degree Award
Martin Origa Jobson Ariel
ID: UNCST-2022-R010809
 Validation of cervical cancer screening methods in Uganda: The National Cancer Management and Capacity building Project in Uganda (CANCAP UG) experience.
REFNo: HS6635ES

To assess multiple screening methods: VIA, PAP smear, HPV, and colposcopy, plus or minus biopsy.,To evaluate the indicators of screening accuracy (sensitivity, specificity, positive predictive value, negative predictive value) of Visual Inspection with Acetic acid (VIA) test by comparing with the gold standard of disease status confirmed via histological results.,
 Uganda 2025-11-21 14:33:45 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
Etheldreda Nakimuli-Mpungu
ID: UNCST-2020-R014808
 Secondary Data Analyses of the Predictors of Depression Treatment Outcomes and Mechanisms of Group Support Psychotherapy in the SEEK-GSP Trial and Translating Findings Through an Upgraded Online Training
REFNo: HS6789ES

Objective 1: Identify predictors of early treatment non-response to depression therapy among people living with HIV (PLWH). Objective 2: Identify psychological and behavioral mechanisms mediating the effect of Group Support Psychotherapy on depression outcomes. Objective 3: Strengthen and upgrade the existing SEEKGSP Academy digital training portal to enhance mental health support for people living with HIV (PLWH).
 Uganda 2025-11-21 14:31:49 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KASIMU SENDAWULA
ID: UNCST-2025-R019643
 Industrial Symbiosis and Scalability of Smallholder Farms in Uganda
REFNo: SS4430ES

To explore the perception of the smallholder farmers regarding the concept of scalability in Uganda

To identify the industrial symbiotic practices being undertaken by smallholder farmers in Uganda.

To investigate the influence of industrial symbiosis on scalability of smallholder farmers in Uganda.

Uganda 2025-11-21 14:20:24 2028-11-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gladness Mtango E
ID: UNCST-2025-R017177
 The Nurses’ Perception of Their Immediate Supervisors’ Servant Leadership Behaviors and Their Sense of Work Effectiveness in Selected Ugandan Public Hospitals
REFNo: SS4419ES

•To explore the relationship between nurses’ perception of servant Leadership and their perceived access to work information such as willingness to share information.,•To determine the relationship between nurses’ perception of Servant Leadership and their perceived access to work resources such as needed equipment and materials.,•To explore the relationship between nurses’ perception of Servant Leadership and their perceived access to work opportunities such as challenging work and opportunities to learn new skills.,To explore if there are differences in job outcomes due to differences in the sizes of hospitals or the tenure of the nurse employee.,To survey and explore the perception of the nurses in the selected public hospitals in Uganda to determine if there is a relationship between their immediate supervisor’s servant leadership behavior and their job outcomes,
 USA 2025-11-21 14:16:50 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
BANGIRANA SEPHAS
ID: UNCST-2025-R020094
 USAGE OF PATIENT RECORDS MANAGEMENT SYSTEM, PSYCHOSOCIAL WORK ENVIRONMENT, WORK TEAM STABILITY, HEALTH CENTRE CHARACTERISTICS, AND QUALITY OF HEALTH CARE IN HEALTH CENTRE IVS IN SOUTH WESTERN UGANDA
REFNo: SS4395ES

General Objective
The aim of the study is to examine the relationship between usage of patient records management system, psychosocial work environment, work team stability, and the quality of health care in HC IVs in South Western Uganda, with health centre characteristics as a moderating variable.
Specific Objectives
i. To establish the relationship between usage of patient records management system usage and the quality of health care among the HC IVs in South-Western Uganda.
ii. To examine the relationship between psychosocial work environment and the quality of health care at HC IVs in South-Western Uganda.
iii. To assess the relationship between work team stability and the quality of health care HC IV in South-Western Uganda.
iv. To examine the combined effect of patient records management, psychosocial work environment, and team stability on the quality of health care at HC IVs in South-Western Uganda.
v. To assess the moderating effect of health centre characteristics in the relationship between psychosocial work environment and quality of health care in HC IVs in South Western Uganda.
 Uganda 2025-11-21 14:13:43 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
 Safety of COVIDEX™ Therapy in adults: in Uganda: A randomized controlled open- label phase 1 clinical trial.
REFNo: HS6540ES

Overall aim
To validate the safety of COVIDEX™ therapy in adult Ugandans.

Specific objectives
Primary objective
To evaluate and document adverse events associated with COVIDEX™ among adults
in Uganda.

Secondary objective:
To determine the plasma concentration of berberine in adults receiving COVIDEX™ at
three different dose levels.
Uganda 2025-11-21 14:11:01 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Candidate Clinical Correlate as Prognostic Outcome for TB (C3PO) Study
REFNo: HS6545ES

Our specific aims are: 1. To evaluate end-of-treatment (EOT) biomarkers as predictors of recurrent TB 2. To evaluate novel cough and activity biomarkers as predictors of post-TB lung health
 Uganda 2025-11-21 13:53:39 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Rubatsimbira Katangaza
ID: UNCST-2024-R004595
 Social economic determinants of energy poverty at household level in Uganda
REFNo: SS4062ES

To what extend do socioeconomic factors determine energy poverty?
What are the energy poverty hotspots in Uganda?
What are the socioeconomic conditions of the most vulnerable households to energy poverty?
 Uganda 2025-11-21 13:49:30 2028-11-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
DANIEL ELAMU
ID: UNCST-2025-R020928
 PREVALENCE OF MALARIA AND HIV IN UGANDAN CHILDREN WITH TRAUMATIC BRAIN INJURY; AN EARLY OUTCOME STUDY.
REFNo: HS6781ES

Primary objective: To determine the prevalence of malaria (by RDT and PCR) and HIV among children presenting with traumatic brain injury at Mulago National Referral Hospital in 8 months.
Secondary Objective: To assess the impact of malaria parasitemia and/or HIV co-infection on short-term functional recovery, measured by Health-Related Quality of Life (HRQoL) at one-month post-discharge.
Uganda 2025-11-21 13:47:46 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women
REFNo: HS6565ES

To evaluate the efficacy of MK-8527 qm compared to FTC/TDF qd for the prevention of HIV-1 infection as assessed by the incidence rate per year of adjudicated HIV-1 infections To evaluate the safety and tolerability of MK-8527 qm compared to FTC/TDF qd.
 Uganda 2025-11-21 11:18:30 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
Francis Ssebiryo
ID: UNCST-2019-R001250
 Mid-Term Evaluation for the Stand Up for Sexual and Reproductive Health Rights Project
REFNo: SS4574ES

To establish a midline value for key performance indicators outlined in the project’s Performance Measurement Framework(PMF), allowing for a direct comparison with the baseline data. To assess progress toward the Outcome Indicators. To establish a midline value for tracking progress against these outcome indicators, as detailed in the project’s Performance Measurement Framework (PMF). To provide recommendations for strategic project improvements
 Uganda 2025-11-19 8:42:04 2028-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 MULTI-COUNTRY OPERATIONAL RESEARCH ON NEW AND EVOLVING FORMS OF VIOLENCE AGAINST WOMEN AND GIRLS LIVING WITH HIV IN UGANDA, KENYA AND TANZANIA
REFNo: SS4545ES

Aim
To conduct a multi-country operational research that examines how new and evolving forms of violence against WLHIV affect their participation in leadership and collective organising within feminist movements in Uganda, Kenya, and Tanzania.

Specific objectives
1.To assess the lived experiences of WLHIV regarding new and evolving forms of violence, and their impact on participation, leadership, and collective organising within feminist movements in Uganda, Kenya, and Tanzania.
2.To examine the experiences of WLHIV who seek or do not seek assistance after experiencing violence, including their access to shelters and support services, and how these factors influence movement-building participation and their advocacy.
3.To analyse, by root cause, how existing barriers hinder WLHIV from receiving assistance and participating meaningfully in coalition-building, advocacy spaces, and feminist leadership.
4.To generate feminist, practice-based evidence and approaches to strengthen inclusive coalitions, leadership pathways, and evidence-informed advocacy under the THRIVE Project at regional levels.
 Uganda 2025-11-19 16:37:11 2028-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mary Kaakyo
ID: UNCST-2025-R019146
 Impact of Differentiated Service Delivery (DSD) Approaches on Viral Suppression and Retention in Care among Adolescents Aged 10-19 Living with HIV in Masaka Region, Uganda
REFNo: HS6682ES

1.Determine the impact of the DSD approaches on viral suppression and retention in care among adolescents aged 10-19 living with HIV in the Masaka region. 2.Explore mechanisms and pathways through which DSD approaches have impacted (or not) viral suppression and retention in care among adolescents aged 10-19 years living with HIV in the Masaka region and the contextual factors that influence these pathways. 3.Estimate the incremental cost-effectiveness of DSD approaches on viral suppression and retention in care among adolescents aged 10-19 years living with HIV in Masaka region.
 Uganda 2025-11-13 17:13:46 2028-11-13 Medical and Health Sciences Non-Clinical Trial Degree Award
JULIET ANENA
ID: UNCST-2025-R022055
 Monitoring the Diversity and Metabolic Shift of Gut Microbes during Fermented Cassava Feeding in an in Vitro Human Colonic Model
REFNo: A667ES

i. To assess the microbial population dynamics during anaerobic fermentation of cassava tubers
ii. To analyse the physicochemical properties and nutrient bioavailability of anaerobically fermented cassava flour
iii. To evaluate the effect of fermented cassava on gut microbial population, diversity, and microbial metabolites

 Uganda 2025-11-13 17:10:56 2028-11-13 Agricultural Sciences Non-Clinical Trial Degree Award
Aisha Nanyiti
ID: UNCST-2021-R013489
 Exploring the option for co-existence of Mabira Forest and the booming economic activity
REFNo: SS4462ES

The main objective is to examine how informational programs can promote co-existence in forest management practices by evaluating their impact on forest community attitudes and conservation behaviors. Precisely.Specific objectives
1. Assess the influence of targeted awareness interventions on forest community members' knowledge of the benefits of optimal forest cover by measuring changes in awareness levels over a 12-month period.
2. Determine the impact of conservation information on the willingness of forest community members to engage in sustainable forest biomass care, quantified by changes in self-reported willingness and observed conservation actions within six months of intervention.
3. Evaluate the behavioral changes in conservation practices among the forest community, specifically tracking actions like reduced logging and increased forest maintenance over 18 months, to establish a direct link between informational programs and sustainable forest stewardship.

 Uganda 2025-11-13 17:08:30 2028-11-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
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