Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Adoke Yeka
ID: UNCST-2021-R004300
 Randomised controlled trial to assess the efficacy of artemisinin combination therapies in a setting of emerging artemisinin resistance in Uganda.
REFNo: HS6327ES

To assess the 42-day clinical and parasitological efficacy of artemether-lumefantrine (AL) and pyronaridine-artesunate (PA) for the treatment of uncomplicated P. falciparum malaria in Uganda.
 Uganda 2025-09-09 16:41:47 2028-09-09 Medical and Health Sciences Clinical Trial Non-degree Award
Mike Mugude
ID: UNCST-2022-R010442
 FEASIBILITY AND ACCEPTABILITY OF USING THE LONG-ACTING CABOTEGRAVIR-RILPIVIRINE INJECTIONS AMONG HIV-INFECTED ADOLESCENTS ATTENDING BOARDING SCHOOLS IN KAMPALA CITY, UGANDA
REFNo: SS4300ES

Primary objective: To understand how the implementation of long-acting
injectable antiretroviral therapy programs can be carried out among
ALHIV who attending boarding school education in Kampala city”.
Secondary objectives:
I. To determine the willingness to use the LA-ART among ALHIV
in boarding schools in Kampala.
II. To determine the acceptability of the LA-ART among ALHIV in
boarding schools in Kampala.
III. To explore the lived experiences of ALHIV regarding the uptake of
oral ART and factors that may influence the use of the LA-ART
boarding schools.
 Uganda 2025-09-09 14:18:00 2028-09-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Deogratius Okengo
ID: UNCST-2025-R017738
 Youth Participation in Akiriket Activities: Pathways to Sustainable Peace in Kotido Municipality Karamoja Uganda.
REFNo: SS4252ES

i. To investigate the roles of youth within Akiriket assemblies in Kotido, Karamoja Uganda
ii. To examine the contributions of youth to sustainable peace by their participation in Akiriket
iii. To identify the challenges for youth to sustain their engagement in Akiriket peace activities

 Uganda 2025-09-09 14:06:52 2028-09-09 Social Science and Humanities Non-Clinical Trial Degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 EVALUATION OF COMMUNITY-BASED INTEGRATED SCREENING AND DIAGNOSIS OF TUBERCULOSIS, ASTHMA AND COPD, AND ITS IMPACT ON ANTIBIOTIC PRESCRIPTIONS IN SELECTED COMMUNITIES IN UGANDA
REFNo: HS6308ES

Sub – study one Primary objective 1. To evaluate the barriers and facilitators of integration of community-based TB, asthma and COPD screening and diagnosis in selected rural and urban communities of Masaka and Wakiso districts. Secondary objective 2. To describe the implementation outcomes of integrating community-based TB, asthma and COPD screening and diagnosis in selected communities of Masaka and Wakiso districts using the RE-AIM framework. Sub – study two Primary Objective 1. To determine the effect of referral of patients, through community screening initiatives, on antibiotics prescriptions patterns and practices in primary health care facilities. Secondary objectives 2. To identify factors influencing provider decisions to prescribe antibiotics to people who screen negative for TB at selected primary health facilities in Masaka, Wakiso and Rakai districts in Uganda. 3. To evaluate patients’ understanding of antibiotics prescription following a negative TB screen in selected communities in Masaka, Wakiso and Rakai districts in Uganda.
Uganda 2025-09-09 14:03:21 2028-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Akulume
ID: UNCST-2023-R005452
 THE USE OF MICRO-ENTREPRENEURSHIP TO STRENGTHEN THE COMMUNITY HEALTH WORKER PROGRAM IN RURAL UGANDA
REFNo: HS6368ES

To describe the access to health care services and products within the study districts To determine the factors that affect how CHEs execute their duties To map geographical information on access to healthcare providers and products in selected clusters. To determine how CHWs execute their work and the factors that affect them. To explore stakeholder�s perception regarding the contribution of community health entrepreneurship to the community health work program To estimate the frequency of use of CHE-services in general and for children <5 suffering from acute fever or diarrhoea To describe the role of CHEs in the care-trajectories for children suffering from acute fever or diarrhoea
Uganda 2025-09-09 14:02:05 2028-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Martha Naluwende
ID: UNCST-2025-R019681
 End Term Evaluation of the Make Way Programme in Uganda
REFNo: SS4114ES

The study aims to evaluate the relevance, effectiveness, coherence, and sustainability of the Make Way programme in Uganda. It will assess how well the programme addressed the SRHR needs of marginalized youth, the impact of its advocacy and capacity-building efforts, and the strength of its partnerships—especially the implementation of the “Leading from the South” approach. Additionally, the study will document lessons learned and good practices to inform future SRHR programming and policy.
 Uganda 2025-09-09 13:59:55 2028-09-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
MARY MUGABEKAZI
ID: UNCST-2024-R002638
 Prevalence and Risk Factors Associated with Recent and Long-Term HIV Infections Among Newly Identified HIV Positive Clients in Kyenjojo District, Western-Uganda
REFNo: HS6381ES

To find out the prevalence and risk factors associated with recent & long-term HIV infections among newly identified HIV positive clients in Kyenjojo District, Western-Uganda.,
 Uganda 2025-09-09 13:48:40 2028-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Atuhaire Rosemary
ID: UNCST-2024-R003132
 Parenting Styles, Students’ Connectedness and Academic Adjustment among Pre- Service Teachers in Universities of South Western Uganda
REFNo: SS3370ES

7. To evaluate the mediating role of student connectedness in the associations between parenting styles and academic adjustment among pre-service teachers in universities in south western Uganda.,6. To investigate the relationship between student connectedness and academic adjustment among pre-service teachers in universities in south western Uganda.,5. To explore the correlation between parenting styles and student connectedness among pre-service teachers in universities in south western Uganda.,4. To examine the relationship between parenting styles and academic adjustment among pre-service teachers in universities in south western Uganda.,3. To assess the levels of academic adjustment among pre-service teachers in universities in south western Uganda.,2. To identify prevalent parenting styles among pre-service teachers in universities in south western Uganda.,1. To investigate how academic adjustment varies across demographic variables among pre-service teachers in universities in south western Uganda.,To investigate the associations between parenting styles, students\' connectedness, and academic adjustment among pre-service teachers in the universities of south western Uganda.,
 Uganda 2025-09-09 13:44:49 2028-09-09 Social Science and Humanities Non-Clinical Trial Degree Award
GRACE ANKUNDA
ID: UNCST-2025-R017443
 TEACHER COMPETENCE, MOTIVATION AND ACTIVE LEARNING OF PRE-PRIMARY SCHOOL CHILDREN IN UGANDA: A CASE OF KABALE DISTRICT
REFNo: SS3854ES

1) To examine the influence of teacher competence on active learning among pre-primary school children in Kabale district. 2) To analyse the effects of teacher motivation on active learning among pre-primary school children in Kabale district. 3) To assess the influence of teacher competence on teacher motivation in pre-primary schools in Kabale District. 4) To investigate the mediating role of teacher motivation in the relationship between teacher competence and active learning among pre-primary school children in Kabale district.
Uganda 2025-09-09 13:42:02 2028-09-09 Social Science and Humanities Non-Clinical Trial Degree Award
MARGARET AANYU
ID: UNCST-2023-R003677
 Adopting multidisciplinary approaches in genetic improvements, nutritional enhancements and climate change adaptation for improved production of Nile tilapia in Uganda
REFNo: A637ES

The main objective of the project is to breed Nile tilapia for improved growth and temperature resilience, and formulation of commercially competitive and environmentally safe fish feeds for sustainable production of Nile tilapia in Uganda. The specific objectives include to: 1. Study effects of elevated water temperature on the growth, survival and physiology of Nile tilapia strains from Ugandan lakes Victoria, Kyoga, Albert, and Edward 2. Select and breed Nile tilapia strains from Ugandan lakes Victoria, Albert, Edward for both improved growth and tolerance to elevated temperature. 3. Develop cost-effective and environmentally safe feeds for fast growing temperature-resilient Nile tilapia strains. 4. Popularising the fast growing Nile tilapia strain resilient to elevated water temperature and the allied feeding regimes.
 Uganda 2025-09-09 13:39:52 2028-09-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 STRIVE 002: An International Observational Study of Adults with Acute Infection
REFNo: HS6420ES

The general aim of this observational study is to is to understand more about what happens when adults are hospitalised with acute infectious diseases.
• Characterise and compare the clinical course and natural history of acute infections of interest
• Determine the percentage who die or develop other adverse outcomes during or following hospitalisation
• Identify host and pathogen risk factors for poor outcomes.
 Uganda 2025-09-09 13:38:25 2028-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AYESIGYE JUSTUS
ID: UNCST-2025-R020078
 SUSTAINABILITY DISCLOSURE INTEGRITY: A PROPOSED GUIDANCE FRAMEWORK FOR THE MANUFACTURING SECTOR IN UGANDA
REFNo: SS4214ES

To assess the scope, quality, comparability, and regulatory alignment of sustainability disclosure practices among sampled Ugandan manufacturing firms in order to identify strengths, gaps, and priority improvement areas To explore the existing sustainability disclosure frameworks in the context of manufacturing sector in Uganda To examine the association between disclosure regime (mandatory vs. voluntary elements) and stakeholder-perceived trustworthiness of sustainability informationTo assess and evaluate existing research methodologies and propose the adoption of an appropriate methodology that addresses the research problem To ascertain the perceptions of sustainability disclosure integrity from professionals and regulators in the context of manufacturing organisations–fieldwork To recommend a proposed guidance framework for enhancing sustainability disclosure integrity in the Ugandan manufacturing sector To conclude the study by offering recommendations and identifying areas for future research
Uganda 2025-09-04 13:17:34 2028-09-04 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel  Obakiro Baker
ID: UNCST-2019-R000065
 ASSESSMENT OF THE PHARMACEUTICAL SYSTEM CAPABILITIES AND CAPACITY TO MANUFACTURE, PROCURE AND DISTRIBUTE ESSENTIAL MEDICINES IN UGANDA (MaPDeM)
REFNo: HS5670ES

To explore the experiences and perceptions of communities on the utilization of pharmaceutical information systems regarding essential medicines,To evaluate the distribution networks and mechanisms for effective delivery of essential medicines to health facilities in Uganda. ,To assess the enablers and barriers for local pharmaceutical manufacturing of essential medicines in Uganda. ,To assess the pharmaceutical system capabilities and capacity to manufacture, procure and distribute essential medicines in Uganda. ,
 Uganda 2025-09-04 12:54:38 2028-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tayebwa Bamwenda James
ID: UNCST-2021-R012825
 SOCIAL SAFEGUARDS IMPLEMENTATION EFFECTIVENESS FOR HYDRO-POWER PROJECTS IN THE NILE BASIN: A CASE OF UGANDA.
REFNo: SS4172ES

1. To analyze the performance indicators of social safeguards for international frameworks on hydro-power projects, identifying implementation gaps at the national level.
2. To assess the implementation process of social safeguards of hydro-power projects in protecting communities, focusing on livelihood restoration, land use, and displacement.
3. To analyze the enabling and hindering factors affecting the implementation of social safeguards in hydro-power projects across the Nile Basin
4. To assess the community coping mechanisms with social safeguards and hydro-power projects in the Nile Basin

Uganda 2025-09-04 12:05:39 2028-09-04 Social Science and Humanities Non-Clinical Trial Degree Award
Ben Broomfield Stuart
ID: UNCST-2025-R017589
 Understanding the evolutionary divergence and adaptation of Afrotropic Aedes (Stegomyia) zoonotic disease vectors using de-novo genome assemblies and comparative genomics
REFNo: NS1002ES

Objective 1- Generate de novo genomes for target Aedes (Stegomyia) species using freshly collected material

Objective 2- Reconstruct demographic history of Aedes mosquitos in African forests

Objective 3- Identify genomic introgression, if any, between closely related Aedes species

Objective 4- Identify genomic regions involved in adaptive divergence between closely related Aedes species

 UK 2025-09-04 12:03:37 2028-09-04 Natural Sciences Non-Clinical Trial Degree Award
Emmanuel Kyasanku
ID: UNCST-2022-R009112
 Seroepidemiology of dengue and other arboviruses and socio-demographic factors associated with seropositvity in Wakiso and Hoima Districts, Uganda.
REFNo: HS6326ES

1. To establish dengue and other arbovirus sero prevalence rates, by antibody detection assays and virus neutralization testing among residents of rural and urban communities, in a retrospective, longitudinal cohort study in Wakiso and Hoima Districts, Uganda, from 2018 through 2024. 2. To establish socio-demographic factors associated with seropositivity, among residents of rural and urban communities in Wakiso and Hoima Districts from 2018 through 2024. 3. To estimate anti-dengue and anti-arbovirus antibodies seroconversion rates among residents of rural and urban communities in Wakiso and Hoima Districts from 2018 through 2024.
 Uganda 2025-09-04 11:45:58 2028-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joanitah  Nalunjogi
ID: UNCST-2023-R008356
 Epidemiology of Household Energy use Burns in Selected Health Facilities in Uganda
REFNo: HS5879ES

1. To estimate the prevalence of household energy use burns in Jinja district, Uganda and factors associated.
2. To determine the relationship between the severity of burns and household energy sources used among patients managed at selected health facilities in Uganda.
3. To determine the factors associated with the eight-month physical, functional and mental outcomes of patients managed for household energy use burns in selected health facilities in Uganda.
4. To explore the experiences and perceptions of patients or caregivers on the causes, prevention and management of household energy use burns in Uganda

 Uganda 2025-09-03 5:14:06 2028-09-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Chris  Opesen C
ID: UNCST-2023-R006913
 Experiences of National Social Scientists in Outbreak Preparedness and Response in Uganda: Challenges and Opportunities for Participation"
REFNo: SS4003ES

1.3.1 General objective
The primary aim of this study is to understand the experiences of national social scientists in SSA and the challenges they have faced with integration during outbreak PPRR activities, with an aim to better integrating their expertise into future PPRR efforts and maximise the use of local human resources.
1.3.2 Specific Objectives
The study’s specific objectives are:
To identify and map the challenges and opportunities for national social scientists’ participation in PPRR, with a particular focus on their experiences in the recent Ebola, COVID-19, Anthrax, Marburg, Cholera, Malaria and Mpox responses.
To collaborate with national social scientists in co-creating evidence, including success stories, that advocates for their increased involvement in outbreak PPRR efforts.
To identify opportunities for providing actionable recommendations that enhance the integration of national social scientists into future outbreak PPRR activities, both within their country’s emergency response framework and internationally within the GOARN.
To contribute to the ongoing decolonisation of global health by amplifying national social scientists’ voices and co-developing strategies that empower social scientists in LMICs.
 Uganda 2025-09-03 5:11:57 2028-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
 Reducing short and long-term consequences of early stunted growth (MAGNUS-2).
REFNo: HS6274ES

To assess the associations between stunting and gut microbiota and function among 6-10-year-old previously stunted Ugandan children.,To assess the associations between stunting and growth, body composition, child development, haemoglobin, micronutrient status and organ size (liver, kidney, spleen) among 6-10-year-old previously stunted Ugandan children,To assess predictors of cardiometabolic risk markers among 6-10-year-old previously stunted Ugandan children,To assess the long-term effects of 3-months supplementation with large-quantity LNS among 1-5-year-old Ugandan stunted children on gut microbiota and function at age 6-10 years. ,To assess the long-term effects of 3-months supplementation with large-quantity LNS among 1-5-year-old Ugandan stunted children on growth, body composition, child development, haemoglobin, micronutrient status and organ size (liver, kidney, spleen) at age 6-10 years,To assess the association between stunting and cardiometabolic risk among 6-10-year-old Ugandan children,To assess the long term effects of 3-months supplementation with large-quantity LNS among 1-5-year old Ugandan stunted children on cardiometabolic risk markers at age 6-10 years.,To assess long-term effects of supplementation with large quantity LNS on child health,
 Uganda 2025-09-03 5:10:27 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Implementation of the International Guidelines for Skin-to-Skin in the First Hour After Birth: Expansion and Sustainability for a Ugandan Hospital in Masaka
REFNo: HS6282ES

To assess the impact of training and support regarding breastfeeding latch and infant feeding practices at around 6 weeks postpartum.,To assess the impact of a rapid change intervention with the staff on the the perineal tears and episiotomies during vaginal birth,To explore and understand the experience of the mothers who experience skin-to-skin contact after birth and their experience of breastfeeding in the postpartum period,To explore and understand the experience of the staff regarding the barriers and enablers to implementing breastfeeding assessment before discharge,To assess the breastfeeding latch and response to breast milk odour of the newborn before discharge with routine care in the first hour and after implementation of immediate, continuous SSC in the hospital,To explore and understand the experience of the staff regarding the barriers and enablers to implementing and sustaining the international guideline for skin-to-skin care in the first hour after birth, and the new recommendation of 90 minutes, and to identify and implement solutions,To understand the newborn\'s experience after birth, the practice change using video ethnography will be increased to 90 minutes and compared with current care practices following the initial introduction of immediate skin-to-skin contact.,To assess the long-term sustainability of uninterrupted skin-to-skin contact (SSC) in the first hour after birth and within 90 minutes after both vaginal and cesarean section. ,To evaluate the implementation, sustainability, and impact of uninterrupted skin-to-skin contact (SSC) in the first hour after birth and increase it for at least 90 minutes at Masaka Regional Referral Hospital, Uganda, focusing on newborn outcomes, maternal experiences, perineal outcomes, healthcare staff perspectives, and its influence on breastfeeding practices,
 Uganda 2025-09-03 5:08:35 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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