Elias Kumbakumba
ID: UNCST-2022-R011183
|
Consortium to Reduce Infant Mortality in Uganda (CONRIM-U)
REFNo: HS6270ES
OBJECTIVES
The overall CONRIM objective is to contribute to the elimination of preventable Neural tube defects (NTDs), Neonatal Sepsis (NS) and the resultant Infectious Hydrocephalus in Uganda.
SURVEILLANCE OBJECTIVES
The study aims to investigate the burden of NS and NTDs within the Busoga subregion, their associated risk factors, the role of genomics in their causation, and the extent to which effective public health interventions and prevention policies can contribute to their reduction.
Specific objectives for the SURVEILLANCE ARM of the CONRIM Unified Protocol include:
1. To estimate the true burden of NTD and NS in Busoga region
In order to achieve this, we will
1.1 Establish comprehensive village level surveillance and build the community network and capacity for accurate routine surveillance on NS and NTDs.
1.2 Employ advanced methods of adaptive surveillance to optimize cost effective observation for NS and NTD at the community level. These can then be extrapolated to other important infant conditions like Malnutrition, and scaled up nationally
2. To determine genetic and environmental contribution to NTD and NS risk and prevention
In order to achieve this, we hope to
2.1 Identify populations or geographical areas that are at increased risk of NS and NTDs in Uganda, for targeted follow-on prevention measures, and policy formation
2.2 Determine whether ancestral genomics might separate different risk groups with similar folate levels. This will lead to optimization of folate for diverse African ancestries.
SAMPLING OBJECTIVES
The general objective of the Sampling Arm is to prospectively diagnose, treat and prevent infant paenibacillus infections.
Specific objectives for the SAMPLING ARM of the CONRIM Unified Protocol include:
3. To evaluate the ability to diagnose Paenibacillus infections at the hospitals.
In order to achieve this objective, we will
3.1 Set up real time qPCR sampling on site at specific sites treating these infants. This will enable the treating clinicians be able to diagnose this infection and plan treatment
3.2 Plan for Nanopore Same Day Sequencing for both Microbe Detection and Antibiotic Resistance determination
4. To determine the optimal treatment for infant paenibacillus infections and evaluate for outcomes.
In order to achieve this objective, we hope to
4.1 Start a prospective registry of infants diagnosed with this infection, focusing on observing treatments and outcomes.
4.2 Lay the foundational work for optimization of brain growth following treatment for infant infections and malnutrition.
5. To identify Sources and Routes of infection leading to infant Paenibacilliosis so as to Prevent these infections
In order to achieve this objective, we will
5.2 Identify potential environmental reservoirs of infant paenibacilliosis.
5.3 Assess for potential transmission routes of infection related to infant care and feeding practices. The consenting mothers whose infants underwent testing for Paenibacillus will be requested to complete a detailed structured interview designed to elucidate the possible pathways of infection stemming from infant care practices.
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Uganda |
2025-07-18 13:55:00 |
2028-07-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Caroline Birungi
ID: UNCST-2021-R012954
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EVALUATING THE EFFECTIVENESS OF INSTRUCTION IN RESPONSIBLE CONDUCT OF RESEARCH ON TRAINEES’ KNOWLEDGE, SKILLS, AND ATTITUDES FOR DECISION-MAKING IN RESEARCH AND PRACTICE IN SOUTHWESTERN UGANDA
REFNo: HS5771ES
1.3.1 General Objective
To evaluate the effectiveness of instruction in responsible conduct of research on trainees’ knowledge, skills, attitudes and behaviors towards decision making in research and practice among those who attended RCR training under the Mbarara University Research Ethics Education Program (MUREEP) from March 2019 to December 2023.
1.3.2 Specific objectives
1. To assess the effectiveness of instruction in RCR offered by MUREEP from March 2019 to December 2023 on trainees' knowledge of the core norms, principles, regulations, and rules governing the practice of research.
2. To evaluate the effectiveness of instruction in RCR offered by MUREEP from March 2019 to December 2023 on trainees’ problem-solving skills for ethical conduct of research.
3. To examine the effectiveness of instruction in RCR offered by MUREEP from March 2019 to December 2023 on trainees’ attitudes and behaviors towards ethical decision-making in research
|
Uganda |
2025-07-18 13:52:09 |
2028-07-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Betty OKOT
ID: UNCST-2021-R013938
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Assessing the Feasibility of Introducing Playful Parenting Intervention for Enhancing School Readiness, Foundational Literacy and Numeracy in a Crisis Context in Uganda
REFNo: SS3839ES
Overall, the study aims to respond to the challenges of providing education in refugee and displacement contexts by assessing the feasibility of implementing a playful parenting intervention to promote school readiness, foundational literacy, and numeracy skills among refugee children.
Study objectives
The following objectives will guide the study:
1) To examine the level of caregivers’ and education stakeholders’ knowledge of playful parenting practices, policies and how they contribute to school readiness and early years education/learning
2) To determine the levels of foundational numeracy and literacy proficiency among children at baseline.
3) To assess the improvement in mean foundational numeracy and literacy levels over 24 months by comparing baseline and post-intervention proficiency scores using standardized assessments.
4) To examine whether interactive play and parental guidance could improve school readiness, foundational literacy and numeracy competencies, parent-child relationships, and socio-emotional skills and resilience in children.
5) To identify facilitators and barriers to playful parenting, school readiness, and foundational literacy and numeracy among refugee learners and recommend alleviating strategies.
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Uganda |
2025-07-18 13:48:28 |
2028-07-18 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
George GALIWANGO William Muwambi
ID: UNCST-2025-R017274
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Descriptive epidemiology of cleft lip and palate in Uganda
REFNo: HS5861ES
To determine the geographical distribution of cleft lip and or palate in Uganda.
To determine the distribution of the types of clefts in Uganda.
To determine the types, frequency and laterality of cleft lip, isolated cleft palate and cleft lip & palate patients in Uganda over the period 2002 to 2024.
To determine the demographics of Ugandans with cleft lip and palate patients who have had surgical repairs in the period 2002 to 2024.
|
Uganda |
2025-07-18 13:46:15 |
2028-07-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Naster Tumwebembeire
ID: UNCST-2023-R006864
|
Isomorphic Forces, Taxpayer Perception and Income Tax Compliance among Small and Medium Enterprises in South Western Uganda
REFNo: SS3828ES
v. To find out whether taxpayer behavior mediates the relationship between taxpayer perception and tax compliance of Small and Medium size Enterprises in Uganda.,iv. To establish whether taxpayer behavior mediates the relationship between isomorphic forces and tax compliance of Small and Medium size Enterprises in Uganda,iii. To determine the relationship between taxpayer behavior and tax compliance of Small and Medium size Enterprises in Uganda,ii. To establish the relationship between taxpayer perception and tax compliance of Small and Medium size Enterprises in Uganda,i. To establish the relationship between isomorphic forces and tax compliance of Small and Medium size Enterprises in Uganda,The study seeks to examine the relationship between isomorphic forces, taxpayer perception and tax compliance of small and medium size Enterprises in Uganda while considering the mediating role of taxpayer behavior in the relationship between isomorphic forces, taxpayer perception and tax compliance,
|
Uganda |
2025-07-18 13:44:31 |
2028-07-18 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Kalidi Rajab
ID: UNCST-2020-R014550
|
Development of a herbal antimalarial syrup from extracts of Cymbopogon citratus, Vernonia amygdalina, Azadirachita indica and Carica papaya
REFNo: HS5837ES
v. To determine the in vivo and in vitro safety a syrup formulated from the most active combination of the extracts of Cymbopogon citratus, Vernonia amygdalina, Azadirachita indica, and Carica papaya.,iv. To determine the in vivo anti-malarial activity of a syrup formulated from the most active combination of the extracts of Cymbopogon citratus, Vernonia amygdalina, Azadirachita indica, and Carica papaya in parasitised Swiss mice.,iii. To establish the quality control assessment parameters of the syrup formulated from the most active combination of the extracts of Cymbopogon citratus, Vernonia amygdalina, Azadirachita indica, and Carica papaya.,ii. To determine the most active combination of the extracts of Cymbopogon citratus, Vernonia amygdalina, Azadirachita indica, and Carica papaya against Plasmodium falciparum.,i. To validate the in vitro anti-plasmodial activity of the extracts of Cymbopogon citratus, Vernonia amygdalina, Azadirachita indica, and Carica papaya against Plasmodium falciparum.,To develop an anti-malarial formulation from extracts of Cymbopogon citratus, Vernonia amygdalina, Azadirachita indica, and Carica papaya.,
|
Uganda |
2025-07-18 13:42:39 |
2028-07-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Emma Steimle
ID: UNCST-2025-R017979
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Medicine, Plant Use, and Conservation in the Rwenzori Region of Uganda
REFNo: SS4042ES
Identify medicinal plants and their uses, understand local residents' health views, and understand the accessibility of medicinal plants
|
USA |
2025-07-14 15:59:38 |
2028-07-14 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
JACKSON TUHIRIRWE
ID: UNCST-2025-R018361
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SACCO PRACTICES AND PERFOMANCE OF SMEs in KABALE District
REFNo: SS4012ES
1) To examine the effect of credit policy by SACCOs and performance of SMEs in Kabale,
2) To establish the effect of Savings on performance the small and medium enterprises in Kabale District.
3) To assess the effect of credit extension on performance of SMEs in Kabale.
4) To establish the effect of financial literacy on performance of SMEs performance in Kabale.
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Uganda |
2025-07-14 15:56:17 |
2028-07-14 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Felix Wamono
ID: UNCST-2024-R003397
|
strengthening medical waste management system in Kampala City,Uganda
REFNo: HS6100ES
General objectives
to establish an efficient on-line automated medical waste management system that shall allow participation of the community and the regulator through the provision of the real time tracking of medical waste from point of generation, collection and disposal hence improving health and environment.
specific objectives
1. to examine the existing medical waste management processes for KCCA health facilities and private clinics within Kampala City
2.to develop an on-line and automated medical waste management system to track and monitor the medical waste management disposal process in KCCA public health facilities and private clinics in all the five divisions of Kampala city
3.to establish medical waste management focal persons in health care facilities.
|
Uganda |
2025-07-14 15:54:30 |
2028-07-14 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Seku Michael .
ID: UNCST-2024-R016404
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An Examination of Child Protection Mechanisms for School Going Children in Conflict-Affected Areas of Kasese District, Uganda
REFNo: SS3967ES
Main objective/ purpose
• To examine the child protection mechanisms for school going children in conflict areas of Kasese district.
Specific Objectives
1. To describe the experiences and perceptions of Community Development Officers regarding tools and techniques used to protect school going children during conflicts.
2. To understand how stakeholders perceive the responsiveness of the Child Protection Helpline in responding to incidents of alarm from school going children during conflicts.
3. To assess how Child Rights Clubs empower school going children to participate in their own protection before, during, and after conflicts.
4. To gather insights from stakeholders on the perceived impact of government programs in protecting school going children from violence, abuse, exploitation, and neglect during conflicts.
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Uganda |
2025-07-14 15:51:51 |
2028-07-14 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
SSEBAGALA CYPRIAN
ID: UNCST-2024-R002071
|
TALENT MANAGEMENT PRACTICES AND EMPLOYEE TURNOVER IN SELECTED HIGHER INSTITUTIONS OF LEARNING IN UGANDA
REFNo: SS3742ES
(i) To examine the effect of Competency Mapping on Employee turnover in higher institution of learning in Uganda
(ii) To assess how Succession management affects Employee turnover in higher institution of learning in Uganda
(iii) To evaluate the effect of Career management on Employee turnover in higher institution of learning in Uganda
(iv) To examine the contributing role of talent management practices on employee turnover in higher institution of learning in Uganda
(v) To evaluate how Workplace Environment moderates the effect of Talent Management Practices on Employee turnover in higher institution of learning in Uganda
|
Uganda |
2025-07-14 15:50:47 |
2028-07-14 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Brian Kibirige
ID: UNCST-2023-R007728
|
The Impact of School-Based Agriculture Education programs on Positive Youth Development in Uganda: A Comparative study.
REFNo: SS3954ES
To develop a comprehensive model that integrates key aspects of positive youth development within Ugandan SBAE programs for secondary school students. ,To measure students’ perceptions of the impact of PYD training within school-based agricultural education (SBAE) programs. ,To compare the Positive Youth Outcomes of Ugandan secondary school students in SBAE programs with YoFFA and those without YoFFA. ,To determine the extent of PYD training integration within school-based agricultural education (SBAE) programs. ,To investigate specific activities of positive youth development within Ugandan school-based agricultural education (SBAE) programs. ,To explore how school-based agriculture education programs in Uganda foster positive youth development among secondary school students.,
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Uganda |
2025-07-14 12:47:20 |
2028-07-14 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Geoffrey Tabo Olok
ID: UNCST-2023-R005911
|
Leveraging ICT affordances to control online abuse of children at home in Gulu City, Northern Uganda
REFNo: SIR509ES
General Objective
The main objective is to develop a dedicated application that offers a multifaceted control of harmful/inappropriate contents at home or outside school environment to minimize children vulnerability during online learning, drawing on insights from psychology (child development), computer science (management of information flow) for education.
Specific Objectives
i. To determine the prevalence of uncontrolled inappropriate and harmful information to learners
ii. To assess knowledge, attitude and practices of parents and teachers towards children protection during online learning
iii. To develop an application to filter inappropriate and harmful information during online learning
iv. To test and validate the effectiveness of the developed application by deploying it on selected devices against which we can verify the filtering capability.
|
Uganda |
2025-07-14 12:43:25 |
2028-07-14 |
Engineering and Technology |
Non-Clinical Trial |
Non-degree Award |
|
Catherine Atahigwa
ID: UNCST-2024-R005083
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Socio-cultural factors and fertility preferences in Southwestern Uganda: A case study of Rubirizi district.
REFNo: SS2907ES
1. To examine how cultural norms and beliefs influence individuals’ attitudes towards
family size and childbearing among women and men in the Rubirizi district.
2. To explore how gender roles and power dynamics within relationships influence
reproductive decision-making among women and men in the Rubirizi district.
3. To investigate how gender and economic status intersect to influence fertility
preferences among men and women in the Rubirizi district.
|
Uganda |
2025-07-14 12:14:00 |
2028-07-14 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Eumu Benard
ID: UNCST-2024-R016554
|
THE IMPLIMENTATION OF THE NATIONAL ENVIRONMENTAL MANAGEMENT POLICY ON SOLID WASTE MANAGEMENT IN UGANDA: A CASE OF URBAN CENTRES IN EASTERN UGANDA
REFNo: SS3555ES
1.4.1 General Objective
The major aim of the study is to assess the implementation of National Environment Management Policy on solid waste management in urban centres in Eastern Uganda.
1.4.2 Specific Objectives
1. To assess the effectiveness of the National Environmental Management Policy implementation mechanisms on Solid Waste Management in Urban centres in eastern Uganda.
2. To establish the extent to which stakeholders are engaged in the implementation of the National Environmental Management Policy towards Solid Waste Management in Urban centres.
3. To examine the influence of policy environment on the implementation of national environmental management policy on Solid Waste Management in Urban centres in Eastern Uganda.
|
Uganda |
2025-07-11 18:03:42 |
2028-07-11 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Felix Magala
ID: UNCST-2024-R016043
|
Incidence of Post-Operative Sore Throat Among Patients Undergoing Open Abdominal Surgery: A Randomized Control Trial Comparing Video and Direct Laryngoscopy
REFNo: HS5685ES
To compare the incidence of POST, and recovery from POST following intubation using Video laryngoscopy or Direct laryngoscopy during general anaesthesia among general surgery patients undergoing laparotomy at MRRH
1. To determine the incidence of POST in the first 24 hours following intubation with either Video-laryngoscopy or Direct-laryngoscopy for patients undergoing open abdominal surgery at MRRH
2. To determine the recovery time from POST among patients intubated with Video laryngoscopy compared to Direct-laryngoscopy.
3. To describe the symptoms associated with POST amongst patients intubated for open abdominal surgery
|
Uganda |
2025-07-11 18:00:56 |
2028-07-11 |
Medical and Health Sciences |
Clinical Trial |
Degree Award |
|
Josephine Tumuhamye NONE
ID: UNCST-2024-R015885
|
Rapid detection of neonatal bloodstream infections using next generation sequencing in Uganda
REFNo: HS5942ES
1. To estimate the proportion of neonates with a possible bloodstream infection with culture-negative sepsis in whom (a) pathogen(s) is identified using NGS
2. To compare the proportion of neonates with a positive blood culture test versus the proportion of neonates with a positive next-generation sequencing test.
3. To compare the sensitivity and specificity of Blood Culture and NGS in identifying (a) pathogen(s) of possible bloodstream infection compared to a composite reference standard (consisting of all microbiological tests and clinical adjudication)
|
Uganda |
2025-07-11 17:59:54 |
2028-07-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Opiyo Solomon
ID: UNCST-2025-R018201
|
Role of Public Libraries in Smart Cities in Uganda
REFNo: SS3927ES
1) Examine the extent to which public libraries are integrated into the technological infrastructure of Smart Cities.
2) Investigate how public libraries support/engage with the Community to foster innovative participation/interaction with Smart City Initiatives.
3) Determine whether public libraries\' involvement in smart city development is significant.
4) Develop recommendations for enhancing the role of public libraries in developing Smart Cities.
|
Uganda |
2025-07-11 17:56:57 |
2028-07-11 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
MUWANGUZI MOSES
ID: UNCST-2021-R013695
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Early childhood adversities, resilience and HIV care outcomes among adolescents and young adults living with HIV in rural Uganda
REFNo: HS6168ES
1) To determine relationship between ACEs and HIV treatment outcomes (ART adherence and
retention in HIV care) among AYLHIV at the HIV adolescent clinic in southwestern Uganda.
2) To determine the mediating role of resilience on the relationship between ACEs and HIV treatment outcomes (ART adherence and retention in HIV care) among AYLHIV at the HIV adolescent clinic in southwestern Uganda.
|
Uganda |
2025-07-11 17:55:44 |
2028-07-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Adrian Kakinda Ivan
ID: UNCST-2024-R015907
|
Exploring Perceived Barriers and Facilitators to Formal and Informal Mental Health Help-Seeking Behaviours of School-Going Adolescents in Uganda.
REFNo: SS4060ES
General Objective
To explore the perceived barriers and facilitators of formal and informal mental health help-seeking behaviours among school-going adolescents in Uganda.
Specific Objectives
1.To identify common MHPs affecting school-going adolescents in Uganda and their impact on their daily functioning.
2.To examine the perceived barriers to formal and informal mental health help-seeking behaviours among school-going adolescents.
3.To explore the facilitators that encourage mental health help-seeking behaviours among school-going adolescents.
4.To assess the role of mental health literacy and stigma in influencing adolescents' help-seeking behaviours.
|
Uganda |
2025-07-11 17:53:17 |
2028-07-11 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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