Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Stephen Gray Blair
ID: UNCST-2025-R019416
Understanding the Role of Play in Promoting Psychosocial Well-being and Learning Among Children in Refugee and Host Communities: A Contextual Study in Adjumani and Obongi Districts
REFNo: SS4275ES

Objectives of the Study This context study aims to generate evidence on how children, parents and guardians, and educators in Adjumani and Obongi districts understand, perceive, and practice play and its implications for education and psychosocial well-being. In particular, this study aims to: ● Understand the cultural and contextual meanings of play and well-being among children, parents and guardians, ECD caregivers and teachers, and community members in West Nile, ● Explore the perceptions of the role of play in supporting children’s psychosocial well-being and learning, ● Document existing practices and norms related to play and psychosocial well-being within families/at home, schools, and communities, and ●Identify barriers and enablers to using play-based learning to support children’s psychosocial well-being.
New Zealand 2025-09-26 18:28:13 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Maryvian Owomugisha
ID: UNCST-2025-R017422
Financial Inclusion, Investment Acumen, Government Interventions and Financial well-being of Ugandan women
REFNo: SS4428ES

1. To examine the extent at which specific financial services have influenced the Financial Well-being of women in Western Uganda.
2. To establish whether government interventions, significantly moderate the relationship between Financial Inclusion and financial well-being of women in Western Uganda.
3. To identify a mediating effect of Investment Acumen on the relationship between financial inclusion and financial well-being of women in western Uganda

Uganda 2025-09-26 18:25:37 2028-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Jackson Musiime Selwano
ID: UNCST-2025-R017885
Enhancing patient flow and quality of care among the edlerly within outpatient clinics of Kabale and Kitagata Hospitals in Southwestern Uganda
REFNo: HS6348ES

Research Questions 1.What are the strengths and weaknesses of the existing elderly patients’ flow management mechanisms in outpatient clinics? 2.How do elderly patients perceive their experiences within the current outpatient flow system? 3.What are the essential components of an optimized patient flow framework for elderly care? 4.How does the implementation of the new patient flow framework impact wait times, efficiency, and patient satisfaction in the pilot clinics?
Uganda 2025-09-26 18:24:27 2028-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Dorothy Akongo
ID: UNCST-2023-R007564
Impact of a Cascading Health Worker Mentorship Project on Pediatric Quality-of-Care in Busoga hospitals, Uganda – a Pre-Post Evaluation
REFNo: HS6427ES

To evaluate the perceptions from the role of mentors and mentees on the impact and sustainability of mentorship,To assess the impact of a structured mentorship program on the quality of pediatric care,To develop and evaluate a mentorship tool as a structure for quality care improvement,To assess the change in selected indicators for quality of pediatric care in six district hospitals in Uganda following the implementation of a structured and regular mentoring program ,
Uganda 2025-09-26 18:21:31 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Angella Mirembe Nanteza
ID: UNCST-2022-R008741
NEURODEVELOPMENTAL OUTCOMES AND ASSOCIATED FACTORS AMONG CHILDREN BORN TO MOTHERS LIVING WITH HIV IN UGANDA.
REFNo: HS6380ES

General objective: To determine the neurodevelopmental outcomes and associated factors among children born to MLHIV in Uganda.
Specific objectives
1. To determine the neurodevelopmental outcomes of children born to MLHIV in the first 18 months of life.
2. To determine the factors associated with neurodevelopmental outcomes of children born to MLHIV in the first 18 months of life.

Uganda 2025-09-26 18:15:44 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
Effect of consumption of cape gooseberries on blood glucose control among patients with type 2 diabetes mellitus in Kampala, Uganda
REFNo: HS6017ES

To evaluate patient adherence to dietary interventions involving gooseberries,To compare change in glycated hemoglobin (HbA1c) levels among T2DM patients consuming gooseberries regularly as part of their diet with those following a regular diet. ,To assess the effect of regular consumption of gooseberries on fasting blood glucose levels in T2DM patients.,To evaluate the effect of cape gooseberries on blood glucose control among patients with T2DM in Kampala, Uganda.,
Uganda 2025-09-26 18:13:11 2028-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Hawa Nalwoga
ID: UNCST-2021-R012081
Innovative Breast Cancer Screening to Increase Early Detection in Uganda Short title: BSESuG Research project
REFNo: HS6166ES

1. To increase knowledge about breast self-examinations (BSE) and BSE practical skills and BSE practise among women in Buhanika subcounty, Hoima district Uganda by at least 50% over a 12-month period
2. To evaluate the effectiveness of the innovative Breast Self-Examination Support Groups (BSESuG) approach in increasing the rate of detecting breast anomalies among women in Buhanika subcounty, Hoima district of Uganda by at least 30% within a 12-month period.
3. To assess the acceptability of the innovative Breast Self-Examination Support Groups (BSESuG) approach for early detection of breast cancer among women in Buhanika subcounty, Hoima district
Uganda 2025-09-26 18:11:17 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CAROLYNE OLEO
ID: UNCST-2024-R003845
DETERMINANTS OF DELAYED HEALTHCARE SEEKING AMONG PATIENTS WITH ABDOMINAL SYMPTOMS AT KYABIRWA SURGICAL CENTER, UGANDA
REFNo: HS6014ES

Main objective/ purpose:
To assess factors influencing decision to seek care in a timely manner among patients presenting with abdominal symptoms at KSC, Budondo sub county

Specific objectives:
1. To determine the median time from symptom onset to presentation among patients presenting with abdominal symptoms to KSC, Budondo sub county
2. To identify factors influencing decision to seek care in a timely manner among patients presenting with abdominal symptoms at KSC, Budondo sub county
3. To understand consequences of delayed presentation, such as increased treatment complexity or cost

Uganda 2025-09-26 18:09:15 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Okema
ID: UNCST-2025-R019099
Insulin storage in low resource settings, impact on the glycated hemoglobin.
REFNo: HS6078ES

To determine the modalities of insulin storage in children and adolescents with T1D in low resource settings and the effects on their Hemoglobin A1C (HbA1C) in northern Uganda
Uganda 2025-09-26 18:07:55 2028-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Jef VanPuyenbroeck
ID: UNCST-2025-R017911
Monitoring anthelmintic resistance in goats in Nwoya District, Uganda
REFNo: A617ES

Main objective:
To assess the efficacy of anthelmintics commonly used by goat farmers in Nwoya district.
Specific Objectives:
1. To determine the prevalence of GIN infesting goats in Nwoya district.
2. To determine nematode species infesting goats in Nwoya district, through coproculture and molecular speciation.
3. To compare the expenses to perform routine FECRT, with McMaster and Mini-FLOTAC, for monitoring anthelmintic resistance in Uganda.
4. To assess the efficiency of survey designs and fecal egg count methods to determine drug efficacy at a certain cost and endemicity.
Belgium 2025-09-26 18:06:25 2028-09-26 Agricultural Sciences Clinical Trial Degree Award
Leah Goldmann
ID: UNCST-2024-R016618
Politicizing The Male Engagement Agenda in Feminist Movements to End Violence Against Women
REFNo: SS3930ES

This research project does not contest the strategy of engaging men in global efforts to EVAW, but rather seeks to investigate the implications of the shift in global emphasis to forwarding men as leaders, authorities, and key actors in efforts to prevent VAW in ways that could have unintended consequences for social justice movements, organizations and institutions that have been historically women-centered, women-led, and survivor-focused.

The research questions include:

Based on the gaps in the literature as described above, we propose the following

Primary Research Question:
What are the implications of the male engagement agenda on local organizations working to end violence against women in the Global South?
Secondary Research Questions:
a. Using women-led organizations working in Kampala, Uganda as a local case study, what are the impacts of the male engagement agenda on funding and programming for these organizations?
b. What is the extent of this impact? How have these organizations experienced this impact?
c. How have organizations navigated these impacts?
d. Using Men Engage Uganda as a comparative site, how and to what extent do members identify both opportunities and challenges in their relationship with feminist organizations?

USA 2025-09-26 18:05:35 2028-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
Digital Evidence Synthesis Tool Innovation Yielding Improvements in Climate and Health
REFNo: SS4343ES

To assess the impact of the evidence products generated using digital tools on climate-health decision-making in Uganda,To assess the use of digital tools in supporting climate-health evidence to policy processes in Uganda,To identify gaps within evidence synthesis processes that necessitate the development of digital tools,To profile the evidence needs of decision makers at the climate-health nexus in Uganda,To comprehensively investigate and enhance the integration of digital tools in climate-health evidence synthesis and decision-making processes in Uganda by profiling decision makers’ evidence needs, identifying gaps in current synthesis methods, evaluating the role of digital solutions, and assessing their impact on policy outcomes.,
Uganda 2025-09-26 18:04:12 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
Applying human-centered design to develop promising Hepatitis B Birth Dose vaccine delivery models for out-of-facility and facility deliveries in Uganda
REFNo: SS4277ES

(1) To develop optimal service delivery model prototypes that enable timely administration of the HepB BD vaccine for both facility and out-of-facility births, thereby increasing vaccination coverage
Uganda 2025-09-26 17:59:03 2028-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Denis Mpairwe
ID: UNCST-2021-R012444
Building inclusive knowledge sharing hubs (Livestock Cafés) for resilient pastoral livelihoods and rangeland restoration in East African drylands (Include2Restore)
REFNo: A621ES

The objective of Include2Restore project is to investigate how rangeland restoration can become sustainable: not only ecologically, but also socially and economically.
The project targets four main objectives:
(1) co-identify rangeland management and restoration practices that will safeguard inclusive and equitable restoration long-term on household and community levels;
(2) co-identify ways to realize new financial returns from rangeland restoration that will safeguard and promote inclusive restoration outcomes long-term;
(3) support and strengthen identified practices within local management structures by integrating them into the Livestock Cafés;
(4) co-test the potential of inclusive, rangeland restoration and sustainable management to build peace through scaling identified best practices by innovating Next Generation Livestock Cafés.
Uganda 2025-09-26 17:52:38 2028-09-26 Agricultural Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
An open-label, randomised, controlled, non-inferiority trial to compare the efficacy, safety and tolerability of a fixed dose Triple Artemisinin-based Combination Therapy (TACT) artemether-lumefantrine-amodiaquine versus first-line Artemisinin-based Combination Therapies (ACTs) for the treatment of uncomplicated Plasmodium falciparum malaria
REFNo: HS6344ES

To compare the efficacy of ALAQ vs AL and ALAQ vs ASAQ as defined by the 28-day PCR corrected adequate clinical and parasitological response (ACPR).
Uganda 2025-09-26 17:41:17 2028-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
A Feasibility and Safety Study of the KeySuite Laparoscopic Devices for Cancer Diagnosis in Uganda
REFNo: SIR493ES

1. To evaluate potential safety issues associated with the use of the KeyScope in patients with intra-abdominal cancers or suspected cancers .
2. To determine the clinical performance of the KeyScope in viewing tissue masses in the abdomen.
3. To determine the clinical performance of the KeyLoop in retraction of the abdominal wall during laparoscopic surgery
4. To determine the acceptability of KeySuite laparoscopic devices in aiding to obtain laparoscopic biopsies

Uganda 2025-09-26 17:12:49 2028-09-26 Engineering and Technology Clinical Trial Non-degree Award
Martin Galiwango
ID: UNCST-2025-R017447
Image Classification in Dermatology: Real Time diagnosis of DCPA using edge computing
REFNo: SIR549ES

1. To identify the most optimal tier in the healthcare system where a DCPA diagnostic device would improve the diagnosis of DCPA based on health workers’ diagnostic accuracy and resource availability. 2. To train a deep learning model that can accurately diagnose DCPA. 3. To validate the deep learning model. 4. To implement the deep learning model on an edge-computing device that ensures data privacy.
Uganda 2025-09-26 16:31:26 2028-09-26 Engineering and Technology Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Focal mass drug administration for the prevention of malaria in pregnancy: a pilot randomized controlled trial.
REFNo: SS4303ES

1. Determine the feasibility and acceptability of a fMDA program with dihydroartemisinin-piperaquine (DP) as a novel component of the MiP prevention package. 2. Estimate the efficacy of fMDA to create a “safe zone” in the immediate home environment and ultimately prevent MiP. ,The scientific objective of this pilot study is to demonstrate the feasibility, acceptability, and preliminary effectiveness of a focal mass drug administration (fMDA) program for household members of pregnant women to protect against malaria in pregnancy (MiP).,
Uganda 2025-09-26 16:24:58 2028-09-26 Social Science and Humanities Non-degree Award
Abdullah Wailagala
ID: UNCST-2025-R019096
Anticipatory Action for Health Service Resilience and Detection (AHEAD) Discovery and Design Study
REFNo: HS6471ES

2) To understand the current and ideal approaches, practices, and perceptions of health workers regarding using risk data and/or information to trigger anticipatory actions.3) To collaboratively co-design, tools and frameworks for anticipatory epidemic risk monitoring and response, drawing on healthcare worker insights, existing workflows, and routine data systems at the primary health care level. 1) To assess the effectiveness and perceived impact of the cIDSR Ebola module released in response to the most recent Ebola outbreak in January 2025 in enhancing health facility readiness and response.
Uganda 2025-09-24 16:38:20 2028-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID  MUBIRU
ID: UNCST-2021-R013091
Epidemiology of Banana Bunchy Top Disease (BBTD) in Uganda: A recently discovered viral disease threatening banana production
REFNo: NS1028ES

1. To determine the genetic diversity of Banana Bunchy Top Virus variants in Uganda. 2. To screen for natural resistance of selected banana accessions against BBTV. 3. To compare the proteomic expression in the BBTV-infected banana in response to varying temperature and drought conditions.
Uganda 2025-09-24 16:36:26 2028-09-24 Natural Sciences Non-Clinical Trial Degree Award
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