Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Confidence  Nkurunungi Asiimwe
ID: UNCST-2024-R015200
 Parent Alcohol Use, Harsh Parenting,Adolescent Alcohol Use and Mental Illness among Adolescents in Kabale District, Southwestern Uganda
REFNo: SS4070ES

1) To examine the association between parent alcohol use and harsh parenting.
2) To determine the association between parent alcohol use and adolescent mental illness.
3) To examine the association between harsh parenting and adolescent mental illness.
4) To find out the association between adolescent alcohol use and adolescent mental illness.
5) To find out whether adolescent alcohol use mediates the association between parent alcohol use, harsh parenting and mental illness.
6) To explore experiences of parents, teachers and opinion leaders in regard to parent alcohol use, harsh parenting, adolescent alcohol use and mental illness.

 Uganda 2025-07-22 15:41:23 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Marion Birungi
ID: UNCST-2024-R016519
 Barriers, Facilitators and Solutions towards Sustainability of Antimicrobial Stewardship Interventions in Selected Ugandan Hospitals. A multiple-methods study
REFNo: SS3741ES

1. To determine the AMS interventions implemented in six selected hospitals in Eastern and Central Uganda.
2. To explore barriers and facilitators of sustainability of AMS interventions in six selected hospitals in Eastern and Central Uganda.
3. To examine how attributes that contribute to sustainability were conceptualized and embedded in the implementation of AMS interventions in six selected hospitals in Eastern and Central Uganda.
4. To assess the sustainability capacity for AMS interventions in six selected hospitals in Eastern and Central Uganda.

 Uganda 2025-07-22 15:25:28 2028-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 EVALUATING HIV EARLY INFANT DIAGNOSIS PERFORMANCE FOR THE ALINITY M HIV-1 ASSAY
REFNo: HS6246ES

1. The primary objective of this protocol is to evaluate the concordance of the Alinity m HIV-1 assay with the cobas HIV-1/HIV-2 Qualitative nucleic acid test for use on the cobas 6800/8800 for early infant diagnosis. The percent agreement will be assessed.
2. The secondary objective is to validate the use of the investigational Alinity m DBS EID Supplement to Alinity m HIV-1 assay using. Specifically, the percent agreement compared to cobas HIV-1/HIV-2 Qualitative nucleic acid test for use on the cobas 6800/8800 will be determined.

 Uganda 2025-07-22 15:23:01 2028-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
bwesigye thaddeus
ID: UNCST-2025-R017892
 Anti-cancer activity of selected medicinal plant species in Kigezi Sub Region of Uganda used by Herbalists
REFNo: NS953ES

i. Identify the medicinal plants species in Kigezi used by herbalists for cancer management in order to document them. ii. Evaluate the effect of the medicinal plants’ extracts used by herbalists on human cancer cell lines in order to determine their cytotoxicity. iii. Evaluate the isolated phytochemical compounds from the anticancer medicinal plant extracts for antioxidant potential to determine their cytotoxic effect on human cancer cell lines. iv. Investigate the cytotoxic effect of phytochemical compounds from the anticancer medicinal plants on human cell lines so as to determine their mechanism of cell death.
Uganda 2025-07-22 15:08:53 2028-07-22 Natural Sciences Non-Clinical Trial Degree Award
LIVINGSTONE MAKANGA KYEGOMBE
ID: UNCST-2024-R015296
 Maternal and perinatal death surveillance and response: Analysis of the processes, factors and challenges of implementation in refugee-hosting districts of west Nile, Uganda
REFNo: HS5996ES

3) To explore the perceptions of stakeholders (including refugees and nationals) on the processes and challenges of implementing MPDSR in refugee-hosting districts of the west Nile region. ,2) To assess factors that influence the implementation of maternal death surveillance and response in Adjumani and Yumbe refugee-hosting districts of west Nile.,1) To assess the processes of implementation of maternal and perinatal death surveillance and response in Adjumani and Yumbe refugee-hosting districts of west Nile. ,To investigate the processes, factors, and challenges of implementation of maternal and perinatal death surveillance and response (MPDSR) in refugee-hosting districts of west -Nile,
 Uganda 2025-07-22 15:07:21 2028-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Joannah Nalwoga
ID: UNCST-2024-R002651
 PREVALENCE AND FACTORS ASSOCIATED WITH OFFERING POST-PARTUM CONTRACEPTION BY HEALTHCARE WORKERS IN KAYUNGA DISTRICT: A CROSS-SECTIONAL STUDY
REFNo: HS6011ES

III. To establish the healthcare facility-related factors associated with using Postpartum contraception in Kayunga District,II. To document the individual-related factors (Knowledge, attitudes, practices) of healthcare workers associated with the use of Postpartum contraception among mothers in Kayunga District.,I. To determine the prevalence of the use of Postpartum contraception among mothers in Kayunga District.,
 Uganda 2025-07-22 15:05:22 2028-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sophia Nakitto
ID: UNCST-2024-R002921
 Prevalence and treatment outcomes of children below 15 years with severe malaria hemoglobinuria, a retrospective study at Kayunga regional referral hospital.
REFNo: HS6156ES

To determine the prevalence of severe malaria among children below 15 years admitted at Kayunga regional referral hospital. To determine the prevalence of severe malaria with hemoglobinuria among children below 15 years admitted at Kayunga regional referral hospital. To identify the factors associated with severe malaria with hemoglobinuria among children below15 years admitted with severe malaria at Kayunga regional referral hospital. To determine the immediate outcomes among children below 15 years managed for severe malaria with haemoglobinuria.
Uganda 2025-07-18 14:52:41 2028-07-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jimmy Haumba Hyuha
ID: UNCST-2024-R002430
 Fit Factors and Job Performance of Administrative Employees: Moderating Effect of Employee Resilience in Public Universities in Uganda
REFNo: SS3933ES

To determine the moderating effect of employee resilience on the relationship beween fit factors and job performance among administrative employees in public universities in Uganda.,To investigate the relationship between employee resilience and the job performance of administrative employees within public universities in Uganda,To examine the impact of fit factors on the job performance of administrative employees within public universities in Uganda,To investigate the moderating effect of employee resilience in relation to fit factors and the job performance of administrative employees within public universities in Uganda.,
 Uganda 2025-07-18 14:51:30 2028-07-18 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Munyangabo
ID: UNCST-2024-R015902
 FROM IN-KIND TO CASH AND VOUCHER ASSISTANCE (CVA): SOCIO-ECONOMIC IMPLICATIONS FOR WELFARE IN HUMANITARIAN ASSISTANCE IN UGANDA
REFNo: SS3896ES

The main objective of the study is to examine the socio-economic implications of the transition from in-kind to cash and voucher assistance on the welfare of refugees and host communities in Uganda.
The following are specific Objectives
1. To investigate enablers and barriers of CVA modality in Uganda.
2. To analyze the socio-economic effects of CVA on the welfare of refugees and host communities in Uganda.
3. To examine the challenges and opportunities in CVA implementation and their implications on humanitarian assistance in Uganda.
 Uganda 2025-07-18 14:50:18 2028-07-18 Social Science and Humanities Non-Clinical Trial Degree Award
Samara Toussaint
ID: UNCST-2025-R016798
 DISPLACED BUT NOT FORGOTTEN: EXPLORING AND ASSESSING INTERSECTIONAL STIGMA, HIV TESTING BEHAVIORS, AND THE ACCEPTABILITY OF HIV SELF-TESTING AMONG REFUGEE WOMEN IN WESTERN UGANDA.
REFNo: SS4001ES

1. Conduct an ethnographic study to explore the experiences and perceptions of HIV-related stigma among refugee women living in Nakivale, Uganda, and how these perceptions influence their HIV testing behaviors. 2. Draw upon principles of community-based participatory research (CBPR) to co-design an HIV self-testing intervention with refugee women residing in Nakivale, Uganda
 USA 2025-07-18 14:48:18 2028-07-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patience Tugume
ID: UNCST-2024-R002213
 KNOWLEDGE, ATTITUDES AND CONSERVATION OF COMMONLY TRADED MEDICINAL PLANTS IN A CLIMATE CHANGING ENVIRONMENT IN EASTERN UGANDA
REFNo: SS3825ES

Main objective
To formulate and design evidence-based interventions to address the loss in medicinal plant diversity in Uganda.
Specific objectives
i.Document commonly traded medicinal plants in Eastern Uganda.
ii.Assess the conservation status of the most commonly traded medicinal plants in Eastern Uganda.
iii.Determine the demographic factors that influence community knowledge and attitudes towards conservation of commonly traded medicinal plants in Eastern Uganda.
iv.Examine the role of cultural beliefs in the sustainable utilization of commonly traded medicinal plants in Eastern Uganda.
v.To design evidence-based intervention that can support and promote sustainable utilization of commonly traded medicinal plants under climate changing conditions in Uganda.
 Uganda 2025-07-18 14:42:43 2028-07-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Alex Twinomuhwezi
ID: UNCST-2024-R016109
 EMPLOYABILITY SKILLS AS A MEDIATOR BETWEEN HUMAN AND STRUCTURAL CAPITAL AND GRADUATE EMPLOYABILITY: A STUDY OF PUBLIC UNIVERSITIES IN SOUTH-WESTERN UGANDA.
REFNo: SS3821ES

1. To examine the association between human capital and graduate employability in public universities in South-Western Uganda.
2. To examine the association between structural capital and graduate employability in public universities in South-Western Uganda.
3. To establish the relationship between employability skills and graduate employability in public universities in South-Western Uganda.
4. To establish whether employability skills mediate the relationship between human capital and graduate employability in public universities in South-Western Uganda.
5. To establish whether employability skills mediate the relationship between structural capital and graduate employability in public universities in South-Western Uganda.
6. To establish the interactive effect of human capital and structural capital on graduate employability.

 Uganda 2025-07-18 14:39:57 2028-07-18 Social Science and Humanities Non-Clinical Trial Degree Award
DICKSON TAYEBWA
ID: UNCST-2021-R012253
 ECOLOGY OF FREE-ROAMING DOGS AND THE CONTROL MEASURES TO ALLEVIATE THE ASSOCIATED PUBLIC HEALTH RISKS IN SELECTED DISTRICTS IN UGANDA
REFNo: HS5222ES

1. To determine the demographics and ecology of free-roaming dogs in Kampala metropolitan area
2. To assess the risk of dog bites and transmission of rabies that free-roaming dogs pose to the community in Kampala metropolitan area
3. To identify viruses of importance to human and animal health circulating in free-roaming dogs in Uganda across a gradient of contact with wildlife
4. To document the dog ownership practices that perpetuate free-roaming dogs in urban and rural settings in Uganda.
5. To assess the dog community sentiments towards free-roaming dogs in urban and rural settings in Uganda.
6. To assess the effectiveness of a sterilization community clinic in managing the population and the public health risks associated with free-roaming dogs

Uganda 2025-07-18 14:35:31 2028-07-18 Medical and Health Sciences Non-Clinical Trial Degree Award
SHAKILLAH  NAMATOVU
ID: UNCST-2022-R009404
 ASSESSMENT OF HUMAN PAPILLOMAVIRUS VACCINATION UPTAKE AND ITS PREDICTORS AMONG FEMALE ADOLESCENTS (10-14 YEARS) IN MBARARA DISTRICT
REFNo: HS6133ES

General Objective
This study aims to assess the level of uptake of the HPV vaccine and its predictors among female
adolescents (10-14 years) in mbarara district
4
1.3.2. Specific Objectives
(i). To assess the level of awareness of and uptake of HPV vaccination among females aged 10-14
years in mbarara district
(ii). To determine factors associated with the uptake of HPV vaccination among females aged 10-
14 years in mbarara distric
 Uganda 2025-07-18 14:30:06 2028-07-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paineto Masengere
ID: UNCST-2021-R013195
 Sustainability of Evidence-Based Interventions for Cardiovascular Disease Prevention in Mukono and Buikwe Districts, Uganda: A Post-Intervention Study
REFNo: HS6237ES

1. Examine the trends of CVD profiles and their determinants in Mukono and Buikwe districts over 10 years (2015-2024).
2. Evaluate the effectiveness of the interventions of the SPICES project for the prevention of CVDs in Mukono and Buikwe districts, Uganda.
3. Assess the sustainability of evidence-based interventions for the prevention of CVDs in Mukono and Buikwe districts, Uganda, three years post SPICES project implementation.
4. Explore the factors influencing the sustainability of evidence-based interventions for the prevention of CVDs in Mukono and Buikwe districts, Uganda.

 Uganda 2025-07-18 14:22:43 2028-07-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Emmanuel Rukundo NSHAKIRA
ID: UNCST-2021-R012277
 Uncertainty and Frictions in Gig Work: Evidence via Conditional Income Guarantee Interventions
REFNo: SS3790ES

This study will identify how interventions designed to reduce uncertainty in earnings may affect labor supply and productivity in the informal gig economy in developing cities.
 Uganda 2025-07-18 14:17:44 2028-07-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Okello Kabagaju
ID: UNCST-2021-R011847
 Digitally Enabled Resilience Policy Innovations (DERPIn)
REFNo: SIR467ES

Main Objective
1. The objective of the proposed data collection is to enhance food system resilience in Uganda by increasing the availability of agricultural data and evidence which will be deployed in a customized AI platform for biophysical data analysis and crop modeling, enabling informed, gender-sensitive, and inclusive policymaking.

Specific Objectives
1. Build Capacity and Promote Knowledge Sharing: Conduct training sessions and outreach activities to empower stakeholders in utilizing the digital tools, data, and insights generated by the project for informed decision-making and policy formulation.
2. Launch a Customized AAgWa Platform: Deploy a user-friendly, interactive AAgWa platform tailored to the Ugandan context, providing data visualization, crop production forecasts, and decision-support tools for various stakeholders.
3. Create Crop Type Classification Maps: Utilize machine learning techniques and spectral signatures to generate high-resolution crop type maps for improved agricultural planning and resource management.
4. Develop and Calibrate Crop Models: Collect primary data on crop types and locations to train and calibrate the Africa Crop Production (AfCP) model for accurate yield forecast

 Uganda 2025-07-18 14:14:27 2028-07-18 Engineering and Technology Non-Clinical Trial Non-degree Award
WINFRED ARINAITWE
ID: UNCST-2024-R015869
 DEVELOPMENT OF A SECURITY FRAMEWORK FOR INFORMATION SHARING-ENABLED INTERNET OF MEDICAL THINGS IN SELECTED HEALTH INSTITUTIONS IN UGANDA
REFNo: SIR480ES

(i) To study existing security frameworks used in Information Sharing IoMT-compatible devices and applications.
(ii) To establish requirements for designing a security framework specific to the needs of Information Sharing-Enabled IoMT systems in selected Ugandan health institutions.
(iii) To develop a tailored security framework for Information Sharing-Enabled Internet of Medical Things.
(iv) To validate the developed Security Framework for Information Sharing-Enabled Internet of Medical Things.

 Uganda 2025-07-18 14:10:11 2028-07-18 Engineering and Technology Non-Clinical Trial Degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
 A Phase 2 Novel Antimicrobial Combination Therapy to Treat Tuberculous Meningitis
REFNo: HS5711ES

1. Assess the safety and efficacy of a novel anti-TB combination regimen with greater bactericidal activity than current standard of care (SOC) therapy
 Uganda 2025-07-18 14:05:06 2028-07-18 Medical and Health Sciences Clinical Trial Non-degree Award
Kiconco KerenHappuchBita
ID: UNCST-2024-R016072
 “TRAINER-TRAINEE MANAGEMENT PROCESSES IN INFORMAL VOCATION EDUCATION TRAINING ARRANGEMENTS IN UGANDA”
REFNo: SS3744ES

1.4 Objectives of the study
i) To find out the management processes engaged in the practice of IVET.
ii) To discover how the informal nature shapes the management processes.
iii) To establish potential factors influencing the trainer –trainee management process of IVET.
iv) To find out coping approaches and strategies utilized in IVET management.


Uganda 2025-07-18 13:58:51 2028-07-18 Social Science and Humanities Non-Clinical Trial Degree Award
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