Jef VanPuyenbroeck
ID: UNCST-2025-R017911
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Monitoring anthelmintic resistance in goats in Nwoya District, Uganda
REFNo: A617ES
Main objective:
To assess the efficacy of anthelmintics commonly used by goat farmers in Nwoya district.
Specific Objectives:
1. To determine the prevalence of GIN infesting goats in Nwoya district.
2. To determine nematode species infesting goats in Nwoya district, through coproculture and molecular speciation.
3. To compare the expenses to perform routine FECRT, with McMaster and Mini-FLOTAC, for monitoring anthelmintic resistance in Uganda.
4. To assess the efficiency of survey designs and fecal egg count methods to determine drug efficacy at a certain cost and endemicity.
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Nwoya, All
Nwoya, All
Nwoya, All
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Belgium |
2025-09-26 18:06:25 |
2028-09-26 |
383 |
All goat herds, kept for livelihood purposes, in Nwoya District will be considered to be included in this study.
|
Ghent University |
Agricultural Sciences |
Clinical Trial |
Degree Award |
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Adoke Yeka
ID: UNCST-2021-R004300
|
An open-label, randomised, controlled, non-inferiority trial to compare the efficacy, safety and tolerability of a fixed dose Triple Artemisinin-based Combination Therapy (TACT) artemether-lumefantrine-amodiaquine versus first-line Artemisinin-based Combination Therapies (ACTs) for the treatment of uncomplicated Plasmodium falciparum malaria
REFNo: HS6344ES
To compare the efficacy of ALAQ vs AL and ALAQ vs ASAQ as defined by the 28-day PCR corrected adequate clinical and parasitological response (ACPR).
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Tororo, Selected parishes
Busia, Selected parishes
|
Uganda |
2025-09-26 17:41:17 |
2028-09-26 |
1680 |
Male or female Participants with acute uncomplicated P. falciparum malaria |
University of Oxford |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Robert Ssekitoleko
ID: UNCST-2019-R001716
|
A Feasibility and Safety Study of the KeySuite Laparoscopic Devices for Cancer Diagnosis in Uganda
REFNo: SIR493ES
1. To evaluate potential safety issues associated with the use of the KeyScope in patients with intra-abdominal cancers or suspected cancers .
2. To determine the clinical performance of the KeyScope in viewing tissue masses in the abdomen.
3. To determine the clinical performance of the KeyLoop in retraction of the abdominal wall during laparoscopic surgery
4. To determine the acceptability of KeySuite laparoscopic devices in aiding to obtain laparoscopic biopsies
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Kampala, Mulago II
|
Uganda |
2025-09-26 17:12:49 |
2028-09-26 |
12 |
The study is targeting 12 adult patients with cancer advised for an intra-abdominal biopsy to be collected for confirmatory. The study will target patients aged between 18 and 60 years. |
National Institute of Health |
Engineering and Technology |
Clinical Trial |
Non-degree Award |
|
Catriona Waitt John
ID: UNCST-2019-R001068
|
Drug Optimisation for LMICs in Pregnant HIV mothers and their INfants: temporary switch to CAB/RPV long acting injections in postpartum period
REFNo: HS5982ES
To characterise drug exposure in breast milk, and drug transfer to infants through breastfeeding, as well as infant drug elimination.
To characterise the elimination of CAB/RPV by describing PK profiles of IM CAB/RPV LA after last injection between 48 and 96 weeks.
To establish strategies on how to safely re-establish oral ART after discontinuation of IM CAB/RPV LA at 48 weeks and switch back to daily oral ART.
To explore early postpartum PK of CAB/RPV in maternal plasma and breastmilk.
To demonstrate antiviral activity and impact on retention in HIV care of temporarily switching to CAB/RPV LA compared with continuation of daily oral ART over 48 weeks.,
|
Kampala, Kampala
|
UK |
2025-09-17 13:21:16 |
2028-09-17 |
309 |
Consenting pregnant women living with HIV |
University of CapeTown |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Ronald Bisegerwa
ID: UNCST-2022-R011022
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Accuracy of Pulse Oximeters with Profound Hypoxia
REFNo: HS6506ES
To generate two to three evidence-based recommendations to regulatory and procurement bodies within six months of study completion to guide pulse oximeter selection for diverse populations.,To collect and contribute data on pulse oximeter accuracy across diverse skin tones to an open-access device performance database by the study’s end, enabling manufacturers to refine pulse oximeter technology and ensure equitable performance across all skin tones, especially in low-resource settings.,To replicate the UCSF Hypoxia Lab in Uganda by establishing a fully equipped and operational facility within a year to evaluate pulse oximeter accuracy across diverse skin tones and hypoxia levels.,To evaluate the accuracy of pulse oximeters under controlled hypoxic conditions in a diverse population in Uganda, with a focus on understanding and addressing disparities in device performance related to skin pigmentation.,
|
Kampala, Kololo
|
Uganda |
2025-09-12 17:03:12 |
2028-09-12 |
432 |
This study will be done on healthy male or female participants between the ages of 18-50 years. |
Association of Anesthesiologists of Uganda |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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