Namulema Edith
ID:
|
Effectiveness of the ‘LeVe CPAP’ against the standard AIRVO CPAP among Covid-19 patients with Acute Hypoxemic Respiratory Failure at Mengo Hospital Kampala Uganda: A Cross-Over Randomised Trial.
REFNo: HS1647ES
The main objective of the trial is to compare the clinical effectiveness of the LeVe CPAP device to the standard AIRVO CPAP in the delivery and maintaining continuous positive airway pressures among patients diagnosed with AHRF at Mengo Hospital Uganda.
|
Kampala, mengo
|
Uganda |
2021-10-28 |
2024-10-28 |
40 |
Male and Female Adult patients with evidence of acute hypoxaemic respiratory failure admitted at the CTU. Any Tribe. |
Leeds Teaching Hospital National Health Service Trust in the UK |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Khamisi Musanje
ID: UNCST-2021-R012863
|
Acceptability, Feasibility and Effectiveness of a Mindfulness based Intervention to Promote Adherence to Antiretroviral Therapy among Adolescents in Kampala.
REFNo: HS1656ES
1. To adapt and explore acceptability of ACT-DNA-v among users (ALWHA) and providers (HCPs).
2. To measure feasibility of the adapted ACT-DNA-v for use with ALWHA.
3. To examine the impact of ACT-DNA-v on reducing proximal psychosocial barriers to medication adherence (depression, anxiety and stigma) among ALWHA.
4. To measure effectiveness of a mindfulness based intervention (ACT-DNA-v) on self-reported adherence among ALWHA in Kampala, and ascertain its impact on viral load reduction via analysis of data from medical records
|
Kampala, Mutundwe
Kampala, Central
|
Uganda |
2021-10-20 |
2024-10-20 |
116 |
Study will be conducted among older adolescents 14-19 years living with HIV attending care at either Kisenyi or Kitebi health centers. Both male and female will be considered. |
Behavioral social science research grant |
Medical and Health Sciences |
Clinical Trial |
Degree Award |
|
Damalie Nalwanga
ID: UNCST-2021-R013217
|
SEVERE PNEUMONIA IN CHILDREN: THE ABILITY OF BODY COMPOSITION TO PREDICT SURVIVAL, AND THE EFFECT OF NUTRITIONAL SUPPLEMENTATION ON OUTCOMES
REFNo: HS1719ES
4. To determine the effect of a nutritional intervention (RUTF) on clinical outcomes (post discharge mortality, re-admission, and occurrence of severe acute malnutrition) of children hospitalized for severe pneumonia.,3. To determine the effect of a nutritional intervention (RUTF) on fat and muscle mass in children hospitalised for severe pneumonia.,2. To compare the ability of various muscle and fat mass indices to predict survival in children hospitalised for severe pneumonia.,1. To describe the role of nutritional status on outcomes following hospitalization for severe pneumonia among children.,To describe the relationship between muscle and fat mass and survival, and determine the role of nutritional supplementation on fat and muscle mass, and on treatment outcomes of children hospitalized for severe pneumonia,
|
,
Jinja,
Mbale,
Soroti,
|
Uganda |
2021-10-20 |
2024-10-20 |
450 |
Children aged 6 months to 12 years hospitalized for severe pneumonia. |
Self Sponsored |
Medical and Health Sciences |
Clinical Trial |
Degree Award |
|
Susan Adakun
ID:
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Comparing adherence to MDR-TB treatment among patients on self-administered therapy and those on Directly Observed Therapy: Non Inferiority Randomized Controlled Trial
REFNo: HS1796ES
Primary Objectives
1. To determine if adherence to MDR-TB treatment among patients on self-administered therapy (measured by Medication Events Monitoring System (MEMS) technology) is non-inferior to that among patients on Directly Observed Therapy (DOT)
Secondary objectives
1. To determine the correlation between serum MDR-TB drug concentrations and adherence as measured by MEMS technology
2. To compare treatment outcomes between MDR-TB patients on self-administered therapy and DOT
|
Kampala, Mulago
Lira,
Mbarara,
|
Uganda |
2021-10-20 |
2024-10-20 |
164 |
Age of study Population: 8 years and above
Gender of study population: Both male and female
Persons of any and all tribes are eligible for study participation as long as they fit the eligibility criteria |
Janssen Global Public Health, a division of Janssen Pharmaceutica NV, under grant number 1550786 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
|
Uganda Paediatric and Adolescent HIV Cohort on Antiretroviral Therapy: Study Protocol (UP-ART)
REFNo: HS1699ES
The objectives of this study are to:
1) Describe the characteristics of children and adolescents living with HIV receiving paediatric care in the participating centres and coverage of ART
2) Describe the uptake of new antiretroviral drugs such as DTG across age groups and regions
3) Assess the effectiveness and safety of new antiretroviral drugs such as DTG, including viral suppression, incidence of adverse events, serious adverse events and discontinuation of drug
4) Assess broader clinical outcomes including retention in care, mortality, disease progression, immune response, viral suppression, overall and by age and treatment regimen/treatment history
5) Assess (i) the prevalence of HIV drug resistance among children/adolescents start of treatment and the impact on treatment response, and (ii) among those who experiencing virological failure on DTG to describe the risk of accumulation of drug resistance (see sub-study Section 4).
|
Hoima, Kahora Division
Lira, Lira
Wakiso, Wakiso
|
Uganda |
2021-10-14 |
2024-10-14 |
3000 |
All children/adolescents attending HIV care at the participating clinics will be invited to join the study |
the International AIDS Society, the World Health Organisation, University College London capacity strengthening grant and UNICEF (grant and in-kind support). |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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