Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
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Exposure-Response Evaluation of IV Artesunate in Children with Severe Malaria
REFNo: HS2027ES
Primary:
• To determine the relationship between dihydroartemisinin (DHA) exposures following intravenous dosing and markers of physiologic dysfunction associated with severe malaria
Secondary:
• To determine the relationship between DHA exposures and time to hospital discharge
• To determine the relationship between DHA exposures and parasite clearance associated with treatment of severe malaria.
Exploratory:
• To determine the relationship between DHA exposures and neurodevelopmental outcomes associated with treatment of severe malaria outcomes and explore predictors that may affect this relationship
• To evaluate the role of parasite clearance as a mediator of the relationship between DHA exposures and markers of physiologic dysfunction associated with severe malaria
• To develop a score comprised of markers of physiologic dysfunction and describe its relationship to clinical outcomes
• To assess P. falciparum infections for artemisinin resistance
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Tororo, central division
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Uganda |
2022-03-14 |
2025-03-14 |
100 |
Children with severe malaria who are 6 months to 14 years of age living in or near Tororo District, Uganda |
VTEU Contract HHSN2722013000221 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Joseph Ngonzi
ID: UNCST-2019-R001579
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Automated visual evaluation and geospatial mapping for cervical cancer screening optimization in sub-Saharan Africa (AVE-Map)
REFNo: HS2069ES
3. To use AVE and geospatial analysis to scale up cervical cancer screening in Uganda ,2. To determine access to cervical cancer screening and referral pathways in Uganda ,1. To validate and expand use of AVE for cervical cancer screening in SSA ,We aim to leverage and develop data science expertise at our sites to first optimize and then combine AVE-based screening by health workers at peripheral health facilities with geospatial-analysis and needs-driven assessment to inform scale-up of cervical cancer screening in Uganda ,
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,
Mbarara, Kakoba
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Uganda |
2022-02-28 |
2025-02-28 |
2000 |
Females aged 25 years and above |
NATIONAL INSTITUTE OF HEALTH |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Musa Sekikubo
ID: UNCST-2021-R014010
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A placebo controlled clinical trial investigating the safety and immunogenicity of GBS6 in pregnant women with and without human immunodeficiency virus (HIV) infection and their infants
REFNo: HS1991ES
1. To describe the safety and tolerability of GBS6 when administered at ? 27 0/7 to ? 35 6/7 weeks’ gestation to pregnant women, with and without HIV, aged ? 18 to ? 40 years of age and their infants..
2. To assess the safety of GBS6 in infants born to HIV positive and negative women who were vaccinated during pregnancy.
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Kampala, Kawempe
Kampala, Kisenyi
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Uganda |
2022-02-11 |
2025-02-11 |
300 |
pregnant women aged 18 to 40 years at gestation age of ? 27 0/7 to ?35 6/7 weeks. |
St George’s, University of London Cranmer Terrace SW17 0RE |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Aisha Nanyiti
ID: UNCST-2021-R013489
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A Randomized Control Trial (RCT) on the Adoption of Liquefied Petroleum Gas (LPG) Cooking Technology among Fast Food (Chapati) Vendors in Uganda
REFNo: SS1017ES
This study seeks to establish the impact of hire purchase schemes and health and safety information on adoption of LPG cookstoves by chapati vendors.
This study will achieve the following specific objectives:
1) The impact of learning from LPG use in grace period before purchase armotisation on adoption of LPG cookstoves by chapati vendors for their businesses and households.
2) The impact of hire purchase on adoption of LPG cookstoves by chapati vendors for their businesses and households.
3) The impact of information on safety and health benefits of LPG on adoption of LPG cookstoves by chapati vendors for their businesses and households.
4) The impact of peer learning from other vendors using LPG cookstoves on adoption of LPG cookstoves by chapati vendors for their businesses and households.
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Kampala,
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Uganda |
2022-02-10 |
2025-02-10 |
210 |
chapatti vendors; they are mainly males of age range in 18-45 years from all districts of Uganda. |
Environment for Development Initiative |
Social Science and Humanities |
Clinical Trial |
Non-degree Award |
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Robert Kalyesubula
ID:
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Effectiveness of a community health worker delivered care intervention for hypertension control in Uganda: a stepped wedge, cluster randomized control trial.
REFNo: HS1917ES
To assess the effectiveness of a CHW-delivered intervention for hypertension control in Uganda.,
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Nakaseke, Kigegge, Bulwadda, Mifunya, Kyamutakasa, Kasambya, Kasagga, North Ward. East Ward. Namilali, Kivule Central Ward
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Uganda |
2022-02-10 |
2025-02-10 |
900 |
Hypertensive patients, 18 years and above, attending Nakaseke hospital or Life Care NCD clinics, and residing either in Nakaseke town council, Nakaseke Subcounty or Kasangombe. |
Else Kroner Fresenius Stiftung |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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