Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Charity Okaba
ID:
Addressing barriers to HIV self-testing in the Private sector among young sexually active females and males in Uganda: A human centred design framework to developing private sector HIVST demand creation, distribution, and linkage models
REFNo: SS955ES

PSI and the Busara Center for Behavioral Economics will conduct qualitative market research that will use targeted questions to gather opinions on barriers and enablers of HIV self-testing in the private sector to uncover insights, opportunities, motivators, and unmet needs. Specifically, the research will employ in-depth interviews and focus group discussions to gather insights on both demand and supply aspects of HIVST as these relate to sexually active females and males of ages 18- 29.

Focus group discussions and in-depth interviews shall be conducted among potential beneficiaries, sexually active females and males of 18 – 29 years to better understand the perceptions and attitudes, barriers and motivators of these groups towards HIV self-testing and responding to the questions with regards to the design of interventions, including delving into the issues or experiences that exacerbate behavioral biases, thereby affecting uptake of HIVST by these populations. The focus group discussions shall consider individuals with experience of using HIV self-test kits and those without experience.
We will also conduct in-depth interviews with private pharmacists, pharmaceutical technologists, and retailers of community drug shops for an understanding of the service provider perspective in selling HIV self-test kits to the target population. In addition, we will also conduct in-depth interviews with manufacturers and distributors of HIV self-test kits to understand supply side barriers and interventions that may hinder or facilitate uptake of HIVST by the target population. Further, we will conduct in-depth interviews with Ministry of Health officials in charge of managing the national HIVST programs including regulatory mechanisms to understand policy and regulatory side barriers and interventions for rolling out HIVST in the private sector.
Uganda 2021-08-10 2024-08-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older
REFNo: HS1638ES

1. To assess, in participants who are SARS-CoV-2 naïve, the
clinical efficacy of the CoV2 preS dTM-AS03 vaccines for
the prevention of symptomatic COVID-19 occurring ≥ 14
days after the second injection.

2. To assess the safety of the CoV2 preS dTM-AS03 vaccines
compared to placebo throughout the study.
Uganda 2021-08-10 2024-08-10 Medical and Health Sciences Clinical Trial Non-degree Award
Twalib Aliku Olega
ID: UNCST-2019-R000474
Uganda Heart Institute Cardiac Catheterization Registry: Patient profile, procedural complications and long-term outcomes
REFNo: HS1081ES

1) to determine the clinical and demographic profile of patients undergoing cardiac catheterization at the UHI
2) to describe complications associated with adult and pediatric cardiac catheterization procedures performed at the UHI and
3) to describe the immediate and intermediate outcomes of patients undergoing adult and pediatric interventional cardiac catheterization at the UHI

Uganda 2021-08-09 2024-08-09 Medical and Health Sciences Non-degree Award
Stephen Sabiiti
ID:
CLINICAL AND HEMATOLOGICAL OUTCOMES OF CHILDREN WITH SICKLE CELL ANEMIA TREATED WITH LOW FIXED-DOSE HYDROXYUREA AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1314ES

1. To describe the clinical and hematological
features of children with sickle cell
anemia at initiation of low fixed-dose
hydroxyurea at MRRH.
2. To describe the changes in hematological
indices after initiation of low fixed dose
hydroxyurea among children with sickle
cell disease at MRRH.
3. To describe the incidence of sickle cell
anemia related clinical events among
children with sickle cell disease treated
with low fixed-dose hydroxyurea at MRRH.
4. To identify factors associated with the
changes in hemoglobin level among children
with sickle cell anemia treated with
low fixed-dose hydroxyurea at MRRH.
Rwanda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Kemigisha Kemigisha
ID:
Adolescents’ Perspectives of sexual wellbeing and consent MUST-2021-37
REFNo: HS1438ES

1) To contribute to the understanding about how local and contextual factors such as predominant religion, socially acceptable norms, cultural practices and political sentiment can influence sexual wellbeing of adolescents (10 to 24 year olds) in LMIC’s, 2) To explore adolescents’ understanding of, and perspectives on, sexual wellbeing, capturing different aspects of sexuality development during adolescence, including the evolving capacity to sexual consent,
Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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