Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Derry Taylor James
ID:
Learned social knowledge in chimpanzees
REFNo: NS269ES

To understand the nature of chimpanzee social knowledge and how it is acquired
 UK 2021-08-11 2024-08-11 Natural Sciences Non-Clinical Trial Non-degree Award
MOSES EGESA
ID: UNCST-2025-R015361
 Epitope mapping of schistosome tegument and alimentary tract proteins in humans
REFNo: HS1463ES

1. To determine the change in antibody reactivity profile of individuals of an endemic area to epitopes of tegument and alimentary tract proteins before and after PZQ treatment
2. To identify antibody reactivity to epitopes putatively associated with protection against reinfection


 Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 Field Performance Evaluation of the m-PIMA™ HIV-1/2 VL plasma assay in Uganda
REFNo: HS1606ES

Main objective
To evaluate the field performance of the m-PIMATM HIV-1/2 VL plasma VL in identifying virological failure (VF) in adults on ART. The performance will be compared to standard PCR assays used at UNHLs and UVRI.
2.3.2 Primary objectives
I). To evaluate the diagnostic accuracy using the sensitivity, specificity, NPV, PPV, FPR and FNR of the m-PIMA™ HIV-1/2 VL plasma assay in comparison to a reference assay of HIV-1 RNA PCR in identifying HIV-VF at the WHO recommended threshold of 1000 copies/ml for HIV-1 infected.
II). To determine the operational characteristics of the m-PIMA™ HIV-1/2 VL plasma assay, such as ease of-use of the assay using the standardized system usability scale (SUS) by laboratory and no laboratory personnel
III). To determine changes in turn-around time and ease of clinic workflow integration.
IV).To determine acceptability of the m-PIMA™ HIV-1/2 VL plasma assay by the study participants

 Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Clinical Trial Non-degree Award
Hiroyuki Takeshima
ID:
Introducing market-oriented horticulture farming in refugee hosting areas of Uganda: An intervention that builds resilience against emergency
REFNo: SS946ES

The objective of the proposed study is to introduce training programs to farmer groups in Northern Uganda, that aim to improve the market profitability of horticulture and thus increase incomes and employment for small farmers in these refugee-hosting regions in Uganda. Such investments are urgently needed to stabilize livelihoods in this region that has suffered through the combinations of challenges posed by the influx of refugees and other challenges including desert locust invasions, and health and economic risks caused by the COVID-19 pandemic. Specifically, the training program target fostering of lead farmers who will then further train other farmers within the community, and transform farmers’ mindset to “produce strategically to sell” rather than “produce and then sell”. Disseminating knowledge through lead farmers (also sometimes known as “model farmers” “village agents”) to a wider group of farmers has been considered an important way to reach and enhance the capacity and mindset of farmers at scale. The program will contribute to stabilizing and boosting farm incomes in vulnerable, refugee-hosting communities and will build the resilience of local livelihoods to COVID-19. The study then collects data on farmers’ market interaction activities and farm production practices before and after the training programs to assess the impacts of these training programs.
 Japan 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
HAPPY WALUSAGA.G. ANNET
ID:
Patients’ Perceptions and Factors Influencing Choice of differentiated service delivery (DSD) models of care in Kampala, Uganda: A Case Study of Immune Suppression Syndrome (ISS)-Clinic Mulago
REFNo: SS957ES

1.To determine the prevalence of utilization of Community clients Led ART model of care among HIV/AIDS clients at ISS clinic- Mulago
2.To determine the factors associated with patients choice of CCLAD model of care among HIV/AIDS clients at ISS clinic- Mulago
3.To explore patients’ perceptions regarding the HIV differentiated models of care

 Uganda 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
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