Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
GRACE NAMBATYA KYEYUNE
ID:
A Phase IIa randomized double-blind, placebo-controlled clinical trial to determine the preliminary safety and efficacy of UBV-01N in adult patients infected with SARS-COV-2 (COVID-19) in Kampala, Uganda.
REFNo: HS1207ES

a) To evaluate the preliminary safety and of UBV-01N, in adult patients diagnosed with COVID-19 and treated with UBV-01N
b) To assess the preliminary efficacy of UBV-01N + standard of care, compared to UBV-01N placebo + standard of care, in adult patients diagnosed with COVID-19, in Kampala, Uganda.

Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
Health-related Quality of Life (HRQoL) of Ugandan children with Sickle Cell Disease (SCD): A comparative study of HRQoL outcomes in the Zinc for Infection Prevention (ZIPS) trial and at the Nalufenya Sickle Cell Clinic (NSCC)
REFNo: HS1069ES

This proposal is designed as a sub-study nested within the ‘Zinc for Infection Prevention in Sickle cell anemia (ZIPS) trial, and has 3 specific aims –

Aim 1: To determine, using a SCD-specific testing instrument, if HRQoL outcomes of children with SCD enrolled in a clinical trial (ZIPS) differ from children with SCD who receive standard of care at the Nalufenya Sickle Cell Clinic (NSCC) in Jinja, Uganda

Aim 2: To determine, using an SCD-specific testing instrument, if HRQoL of children with SCD in the ZIPS study differs between those on zinc supplementation vs. those on placebo

Aim 3: To document caregiver perceptions regarding factors influencing HRQoL of children with SCD in the ZIPS study (those on zinc supplementation vs. those on placebo) and those receiving standard of care at the Nalufenya Sickle Cell Clinic (NSCC) in Jinja, Uganda

Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
Evaluating the effect of private provider engagement on access to TB screening and diagnostic services in two large urban districts in Uganda: an observational study.
REFNo: HS1106ES

The overall aim of this study is to determine the effect of private health providers on access to TB diagnostic services in two large urban cities in Uganda.

The primary objective will be to:
1. To examine the effect of community pharmacies’ engagement on a) time to TB treatment and b) costs incurred while seeking care for TB by patients with bacteriologically confirmed TB in the PRES project in Kampala and Wakiso

The secondary objectives will be to
2. To understand community pharmacies’ perspectives towards provision of TB screening services and linkage to treatment.
3. To identity other infectious causes of cough among patients who are screened for TB at community pharmacies

Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
JUSTINE NAMWAGALA MUKOSE
ID:
Explorative investigation of the burden and risk factors of uvula infections and associated traditional uvulectomy practices in Luwero district and surrounding areas
REFNo: HS1167ES

OBJECTIVES


The overarching objective of this explorative research study is to investigate and document, in a scientifically sound manner, the condition called “akamiro”; determine the case definition, describe its general epidemiology including the beliefs and perceptions around it and the traditional surgical procedure, and commence etiological investigations.


Our proposed specific objectives are;

1. To determine the clinical case definition of the uvula infections called “akamiro” – general and age-specific case definitions for infants, children, adolescents and adults.
2. To investigate major risk factors of uvula infections /“akamiro”.
3. To determine the magnitude and associated factors of uvula infections /“akamiro”, and geo-map its spread.
4. To determine the prevalence of traditional uvulectomy and its outcomes and sequelae.

5. To establish the community beliefs, perceptions and practices associated with “akamiro”.

Uganda 2021-01-25 2024-01-25 Medical and Health Sciences Non-degree Award
Munshi Sulaiman
ID:
Women’s Leadership in Village Savings and Loan Associations (VSLAs) in Uganda
REFNo: SS685ES

The research has two key objectives. The first is to understand the current starus and barriers of women to take leadership roles in VSLA committees. The second objective is to identify possible interventions that can strengthen their leadership roles.
Bangladesh 2021-01-25 2024-01-25 Social Science and Humanities Non-degree Award
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