Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joseph  Olobo Okao Olobo
ID:
A multicentre observational study to assess immune response status in patients before and after treatment for visceral leishmaniasis
REFNo: HS1266ES

Primary Objective To assess systemic and skin immune responses and parasite load in patients before, and at end of treatment for visceral leishmaniasis
Secondary Objectives
1. To identify systemic and local immune correlates of treatment outcome.
2. To evaluate parasite genotype in relation to immune response characteristics
3. To compare immunology and parasitological data across each site and determine possible correlates of progression to PKDL


Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
Formative research to inform the design of a youth-led self-care intervention to increase uptake of voluntary family planning and reproductive health care services among adolescent girls (10-19 years) in Uganda
REFNo: HS1294ES

The overall objective of the study will be to explore adolescent girls perceptions towards provision of self-care FP services and stakeholders’ perceptions towards provision of voluntary FP and RHC information and services to adolescent girls aged 10-19 years by fellow adolescents in order to inform the design of a youth-led self-care intervention to improve uptake of voluntary FP and RHC services to adolescent girls aged 10-19 years in Uganda. Specifically, this study will aim to:
1. Determine differentials in teenage pregnancy rates and contraceptive use by socio-demographic and behavioural characteristics
2. Assess the association between modern contraceptive use and teenage pregnancy rates among adolescents (15-19 years) across the different demographic and health surveys.
3. Explore the FP and RHC information and service needs of the very young adolescent girls (10-14 years) and older adolescents (15-19 years).
4. Explore mechanisms through which adolescent girls (10-19 years) can be involved in the design and delivery of voluntary FP and RHC interventions for fellow adolescents.
5. Explore adolescent girls’ perceptions about self-care FP methods and whether or not self-care FP methods can help to reduce the barriers that adolescents face in accessing and utilizing FP services.
6. Explore key stakeholders’ perceptions towards: a) provision of self-care FP information and services to adolescents; and b) provision of voluntary FP and RHC information and services to adolescent girls aged 10-19 years by fellow adolescents.
7. Explore key stakeholders’ perceptions on the acceptability of an intervention that entails provision of FP and RHC information and services to adolescent girls (10-19 years) by fellow adolescent girls.
8. Explore the barriers to and facilitators of interventions that provide FP and RHC information and services to adolescent girls by adolescent girls in the target districts and how provision of such information and services to adolescent girls by fellow adolescent girls can be improved.
Uganda 2021-08-16 2024-08-16 Medical and Health Sciences Non-degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
Advancing the health of rural communities in Uganda through strong community health programs
REFNo: SS872ES

4.3 General Objective
To evaluate non-monetary incentive packages required for strengthening the community health workforce, which provides critical health services to the rural poor in Masindi District.

Specific objectives
i. To identify the priorities of the national government regarding compensation packages for the VHTs in Masindi District.
ii. To assess how the national government compensation packages align with the priorities of the VHTs in Masindi District.
iii. To identify the structure and group of incentives best suited to motivate VHTs, improve their performance in the delivery of services, and increase their retention in the health workforce in Masindi District.
iv. To identify the behavioural mechanism through which the new incentives may work or fail to work in Masindi District
v. To understand how changes in the national VHT program impact utilization of maternal and child health services, sanitary practices and perception of quality of health services at the community-level



Uganda 2021-08-16 2024-08-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Manjari Quintanar-Solares
ID:
MICROARRAY PATCH FOR PEDIATRIC ANTIRRETROVIRAL TREATMENT STAKEHOLDER INTERVIEWS IN UGANDA
REFNo: HS1359ES

To define the target product profile (TPP) and preferred user characteristics, identify stakeholder needs, and evaluate potential acceptability of a pediatric ARV MAP
Mexico 2021-08-16 2024-08-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eun Seok Kim
ID:
Cross-sectional prevalence study of schistosomiasis and soil-transmitted helminthiasis with nested open-label randomised controlled study of evaluating the impact of fatty meal co-administration and double-dosing on albendazole effectiveness against hookworm infection among school-aged children in Mayuge district: Implications for Mayuge NTDs Elimination (MANE) Project
REFNo: HS1411ES

Objective 1: To determine the effect of albendazole administration with a fatty meal such as avocado, versus albendazole administration without a fatty meal, on hookworm cure rate and egg reduction rate.

Objective 2: To determine the effectiveness of dual-dose (400mg/day, two consecutive days) versus single-dose (400mg) albendazole treatment regimens on hookworm cure rate and egg reduction rate.

Objective 3: To identify and evaluate environmental, social and cultural variables affecting hookworm infection, and cure rate and egg reduction rate of albendazole against hookworm.

South Korea 2021-08-16 2024-08-16 Medical and Health Sciences Clinical Trial Degree Award
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